4N3PA

Crystal structure of de novo designed serine hydrolase osh18, northeast structural genomics consortium (nesg) target or396
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
428
structure length
424
Chain Sequence
MKLKTNIRHLHGIIRVPGDSSISVLSIIFGSLAEGETKVYDILRGEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGASIVAISGVLAGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHYELPIASNSVKSALMFAALQAKGESVIIEKEYTSNHTEDMLQQFGGHLSVDGKKITVQGPQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGIEETLTGIIDVIRAMGGKLEITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAEELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAIAALLVADGEVELDRAEAIPSFFDDLESLIHGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396
rcsb
molecule tags Hydrolase
source organism Synthetic construct
molecule keywords Serine Hydrolase OSH18
total genus 113
structure length 424
sequence length 428
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-10-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 4n3pA02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 4n3pA01
2Z2CA 3UPKA 3KQJA 1P88A 1RF4A 1RYWA 3ZH4A 1X8RA 1YBGA 2PQCA 4E7DA 4E7GA 2O0BA 1Q3GA 2O0XA 3RMTA 1EJDA 1G6TA 3SG1A 3SWQA 2YVWA 3SWDA 3SPBA 3SWAA 3SWEA 4GFPA 3V5VA 3R38A 3FJZA 1Q36A 3ISSA 2QFQA 4EGRA 1EYNA 4E7EA 1EJCA 3KR6A 3LTHA 2AA9A 1UAEA 2O0ZA 1RF5A 4ZNDA 1RF6A 2PQ9A 3SWGA 3KQAA 2O0EA 4E7BA 4E7FA 3ZH3A 3TI2A 2PQDA 2QFSA 5BUFA 4R7UA 4E7CA 4N3PA 3SWIA 3TR1A 1DLGA 3SLHA 4EIIA 1A2NA 2O15A 3FK1A 2BJBA 1MI4A 2PQBA 2RL2A 5BS5A 3FJXA 5BQ2A 3FK0A 2QFTA 2GGDA 2O0DA 3VCYA 3NVSA 1X8TA 1P89A 3SU9A 3V4TA 2RL1A 2GG6A 2AAYA 1NAWA 2QFUA 2GG4A 3ROIA 4FQDA 2GGAA 5U4HA 1G6SA
chains in the Genus database with same CATH superfamily
2Z2CA 3UPKA 3KQJA 1P88A 1RF4A 1RYWA 4CLQA 3ZH4A 1X8RA 3KGDA 1YBGA 3TW3A 2PQCA 4E7DA 4E7GA 2O0BA 1Q3GA 2O0XA 3RMTA 1EJDA 1G6TA 3TUXA 4O89A 3TV1A 3SG1A 3SWQA 2YVWA 3SWDA 3SPBA 3SWAA 3SWEA 4GFPA 3V5VA 3R38A 3FJZA 1Q36A 3ISSA 2QFQA 4EGRA 1EYNA 4E7EA 1EJCA 3KR6A 3LTHA 2AA9A 1UAEA 2O0ZA 1RF5A 4ZNDA 1RF6A 2PQ9A 3SWGA 3KQAA 2O0EA 4E7BA 4E7FA 3ZH3A 3TI2A 2PQDA 2QFSA 5BUFA 4R7UA 4E7CA 4N3PA 3SWIA 3TR1A 1DLGA 3SLHA 4EIIA 1A2NA 2O15A 3FK1A 2BJBA 1MI4A 2PQBA 2RL2A 1QMHA 5BS5A 3FJXA 5BQ2A 4O8JA 3FK0A 2QFTA 1QMIA 3TUTA 2GGDA 2O0DA 3VCYA 3NVSA 1X8TA 1P89A 3SU9A 3V4TA 2RL1A 2GG6A 2AAYA 1NAWA 2QFUA 2GG4A 3ROIA 4FQDA 2GGAA 3PQVA 5U4HA 1G6SA
chains in the Genus database with same CATH topology
2Z2CA 3UPKA 3KQJA 1P88A 1RF4A 1RYWA 3ZH4A 1X8RA 1YBGA 2PQCA 4E7DA 4E7GA 2O0BA 1Q3GA 2O0XA 3RMTA 1EJDA 1G6TA 3SG1A 3SWQA 2YVWA 3SWDA 3SPBA 3SWAA 3SWEA 4GFPA 3V5VA 3R38A 3FJZA 1Q36A 3ISSA 2QFQA 4EGRA 1EYNA 4E7EA 1EJCA 3KR6A 3LTHA 2AA9A 1UAEA 2O0ZA 1RF5A 4ZNDA 1RF6A 2PQ9A 3SWGA 3KQAA 2O0EA 4E7BA 4E7FA 3ZH3A 3TI2A 2PQDA 2QFSA 5BUFA 4R7UA 4E7CA 4N3PA 3SWIA 3TR1A 1DLGA 3SLHA 4EIIA 1A2NA 2O15A 3FK1A 2BJBA 1MI4A 2PQBA 2RL2A 5BS5A 3FJXA 5BQ2A 3FK0A 2QFTA 2GGDA 2O0DA 3VCYA 3NVSA 1X8TA 1P89A 3SU9A 3V4TA 2RL1A 2GG6A 2AAYA 1NAWA 2QFUA 2GG4A 3ROIA 4FQDA 2GGAA 5U4HA 1G6SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z2C A;  3UPK A;  3KQJ A;  1P88 A;  1RF4 A;  1RYW A;  3ZH4 A;  1X8R A;  1YBG A;  2PQC A;  4E7D A;  4E7G A;  2O0B A;  1Q3G A;  2O0X A;  3RMT A;  1EJD A;  1G6T A;  3SG1 A;  3SWQ A;  2YVW A;  3SWD A;  3SPB A;  3SWA A;  3SWE A;  4GFP A;  3V5V A;  3R38 A;  3FJZ A;  1Q36 A;  3ISS A;  2QFQ A;  4EGR A;  1EYN A;  4E7E A;  1EJC A;  3KR6 A;  3LTH A;  2AA9 A;  1UAE A;  2O0Z A;  1RF5 A;  4ZND A;  1RF6 A;  2PQ9 A;  3SWG A;  3KQA A;  2O0E A;  4E7B A;  4E7F A;  3ZH3 A;  3TI2 A;  2PQD A;  2QFS A;  5BUF A;  4R7U A;  4E7C A;  4N3P A;  3SWI A;  3TR1 A;  1DLG A;  3SLH A;  4EII A;  1A2N A;  2O15 A;  3FK1 A;  2BJB A;  1MI4 A;  2PQB A;  2RL2 A;  5BS5 A;  3FJX A;  5BQ2 A;  3FK0 A;  2QFT A;  2GGD A;  2O0D A;  3VCY A;  3NVS A;  1X8T A;  1P89 A;  3SU9 A;  3V4T A;  2RL1 A;  2GG6 A;  2AAY A;  1NAW A;  2QFU A;  2GG4 A;  3ROI A;  4FQD A;  2GGA A;  5U4H A;  1G6S A; 
#chains in the Genus database with same CATH topology
 2Z2C A;  3UPK A;  3KQJ A;  1P88 A;  1RF4 A;  1RYW A;  4CLQ A;  3ZH4 A;  1X8R A;  3KGD A;  1YBG A;  3TW3 A;  2PQC A;  4E7D A;  4E7G A;  2O0B A;  1Q3G A;  2O0X A;  3RMT A;  1EJD A;  1G6T A;  3TUX A;  4O89 A;  3TV1 A;  3SG1 A;  3SWQ A;  2YVW A;  3SWD A;  3SPB A;  3SWA A;  3SWE A;  4GFP A;  3V5V A;  3R38 A;  3FJZ A;  1Q36 A;  3ISS A;  2QFQ A;  4EGR A;  1EYN A;  4E7E A;  1EJC A;  3KR6 A;  3LTH A;  2AA9 A;  1UAE A;  2O0Z A;  1RF5 A;  4ZND A;  1RF6 A;  2PQ9 A;  3SWG A;  3KQA A;  2O0E A;  4E7B A;  4E7F A;  3ZH3 A;  3TI2 A;  2PQD A;  2QFS A;  5BUF A;  4R7U A;  4E7C A;  4N3P A;  3SWI A;  3TR1 A;  1DLG A;  3SLH A;  4EII A;  1A2N A;  2O15 A;  3FK1 A;  2BJB A;  1MI4 A;  2PQB A;  2RL2 A;  1QMH A;  5BS5 A;  3FJX A;  5BQ2 A;  4O8J A;  3FK0 A;  2QFT A;  1QMI A;  3TUT A;  2GGD A;  2O0D A;  3VCY A;  3NVS A;  1X8T A;  1P89 A;  3SU9 A;  3V4T A;  2RL1 A;  2GG6 A;  2AAY A;  1NAW A;  2QFU A;  2GG4 A;  3ROI A;  4FQD A;  2GGA A;  3PQV A;  5U4H A;  1G6S A; 
#chains in the Genus database with same CATH homology
 2Z2C A;  3UPK A;  3KQJ A;  1P88 A;  1RF4 A;  1RYW A;  3ZH4 A;  1X8R A;  1YBG A;  2PQC A;  4E7D A;  4E7G A;  2O0B A;  1Q3G A;  2O0X A;  3RMT A;  1EJD A;  1G6T A;  3SG1 A;  3SWQ A;  2YVW A;  3SWD A;  3SPB A;  3SWA A;  3SWE A;  4GFP A;  3V5V A;  3R38 A;  3FJZ A;  1Q36 A;  3ISS A;  2QFQ A;  4EGR A;  1EYN A;  4E7E A;  1EJC A;  3KR6 A;  3LTH A;  2AA9 A;  1UAE A;  2O0Z A;  1RF5 A;  4ZND A;  1RF6 A;  2PQ9 A;  3SWG A;  3KQA A;  2O0E A;  4E7B A;  4E7F A;  3ZH3 A;  3TI2 A;  2PQD A;  2QFS A;  5BUF A;  4R7U A;  4E7C A;  4N3P A;  3SWI A;  3TR1 A;  1DLG A;  3SLH A;  4EII A;  1A2N A;  2O15 A;  3FK1 A;  2BJB A;  1MI4 A;  2PQB A;  2RL2 A;  5BS5 A;  3FJX A;  5BQ2 A;  3FK0 A;  2QFT A;  2GGD A;  2O0D A;  3VCY A;  3NVS A;  1X8T A;  1P89 A;  3SU9 A;  3V4T A;  2RL1 A;  2GG6 A;  2AAY A;  1NAW A;  2QFU A;  2GG4 A;  3ROI A;  4FQD A;  2GGA A;  5U4H A;  1G6S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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