1NFHA

Structure of a sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of dna-binding
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
86
structure length
86
Chain Sequence
HVVYVGNKPVMNYVLATLTQLNEGADEVVIKARGRAISRAVDVAEIVRNRFMPGVKVKEIKIDTEELESEQGRRSNVSTIEIVLAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA-binding
pubmed doi rcsb
molecule tags Gene regulation
source organism Archaeoglobus fulgidus
molecule keywords conserved hypothetical protein AF1956
total genus 20
structure length 86
sequence length 86
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01918 Alba Alba
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.110.20 Alpha Beta 2-Layer Sandwich Translation Initiation Factor IF3 Alba-like domain 1nfhA00
2EH1A 1NFHA 2A2YA 2Z7CA 1NH9A 3WBMA 2Q3VA 1H0YA 1UDVA 1H0XA 2BKYX 4Z9EA 1NFJA 3TOEA 1Y9XA 2EK0A 2H9UA 1VM0A 3IABA 3IABB 3U6YA
chains in the Genus database with same CATH superfamily
4NCXA 1NFHA 1HC7A 3TSQA 2Q3VA 1NJ1A 2P9BA 1XEZA 2BKYX 1H4TA 3DSCA 2CRQA 2EK0A 4FCXA 1JDQA 4HVZA 4HD0A 1H4QA 3DSDA 3IALA 1H4SA 1NJ2A 4K88A 4YKEA 3ZIHA 2A2YA 2Z7CA 1H0YA 2GTCA 3LVKB 2L8YA 1UDVA 4FBKA 3T1IA 2M71A 3P04A 4Z9EA 1NFJA 1RQ8A 1VM0A 1Y9XA 4OLFA 3TSPA 4YDQA 1Y2IA 4NZTM 4WI1A 2EH1A 1II7A 3TTFA 1NH9A 1S8EA 2IFEA 4FBQA 3LVJC 2LXRA 1TIGA 4K86A 3TTCA 3TTDA 1DCJA 2Y1BA 3TOEA 1NJ6A 2H9UA 1NJ8A 3IABA 3U6YA 3VTHA 3ZIIA 4NZRM 3WBMA 3HZ7A 3QKBA 1LN4A 3ZIGA 1H0XA 1NJ5A 4EO0A 3ZIEA 4HVCA 3VTIA 4FBWA 1VR4A 4K87A 1JO0A 4TWAA 3TSUA 1PAVA 4Q15A 2LN3A 3IABB 1JE3A
chains in the Genus database with same CATH topology
2EH1A 1NFHA 2A2YA 2Z7CA 1NH9A 3WBMA 2Q3VA 1H0YA 1UDVA 1H0XA 2BKYX 4Z9EA 1NFJA 3TOEA 1Y9XA 2EK0A 2H9UA 1VM0A 3IABA 3IABB 3U6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EH1 A;  1NFH A;  2A2Y A;  2Z7C A;  1NH9 A;  3WBM A;  2Q3V A;  1H0Y A;  1UDV A;  1H0X A;  2BKY X;  4Z9E A;  1NFJ A;  3TOE A;  1Y9X A;  2EK0 A;  2H9U A;  1VM0 A;  3IAB A;  3IAB B;  3U6Y A; 
#chains in the Genus database with same CATH topology
 4NCX A;  1NFH A;  1HC7 A;  3TSQ A;  2Q3V A;  1NJ1 A;  2P9B A;  1XEZ A;  2BKY X;  1H4T A;  3DSC A;  2CRQ A;  2EK0 A;  4FCX A;  1JDQ A;  4HVZ A;  4HD0 A;  1H4Q A;  3DSD A;  3IAL A;  1H4S A;  1NJ2 A;  4K88 A;  4YKE A;  3ZIH A;  2A2Y A;  2Z7C A;  1H0Y A;  2GTC A;  3LVK B;  2L8Y A;  1UDV A;  4FBK A;  3T1I A;  2M71 A;  3P04 A;  4Z9E A;  1NFJ A;  1RQ8 A;  1VM0 A;  1Y9X A;  4OLF A;  3TSP A;  4YDQ A;  1Y2I A;  4NZT M;  4WI1 A;  2EH1 A;  1II7 A;  3TTF A;  1NH9 A;  1S8E A;  2IFE A;  4FBQ A;  3LVJ C;  2LXR A;  1TIG A;  4K86 A;  3TTC A;  3TTD A;  1DCJ A;  2Y1B A;  3TOE A;  1NJ6 A;  2H9U A;  1NJ8 A;  3IAB A;  3U6Y A;  3VTH A;  3ZII A;  4NZR M;  3WBM A;  3HZ7 A;  3QKB A;  1LN4 A;  3ZIG A;  1H0X A;  1NJ5 A;  4EO0 A;  3ZIE A;  4HVC A;  3VTI A;  4FBW A;  1VR4 A;  4K87 A;  1JO0 A;  4TWA A;  3TSU A;  1PAV A;  4Q15 A;  2LN3 A;  3IAB B;  1JE3 A; 
#chains in the Genus database with same CATH homology
 2EH1 A;  1NFH A;  2A2Y A;  2Z7C A;  1NH9 A;  3WBM A;  2Q3V A;  1H0Y A;  1UDV A;  1H0X A;  2BKY X;  4Z9E A;  1NFJ A;  3TOE A;  1Y9X A;  2EK0 A;  2H9U A;  1VM0 A;  3IAB A;  3IAB B;  3U6Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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