2I82A

Crystal structure of pseudouridine synthase rlua: indirect sequence readout through protein-induced rna structure
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
217
structure length
217
Chain Sequence
MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
pubmed doi rcsb
molecule keywords 5'-R(*GP*AP*GP*GP*GP*GP*AP*UP*UP*GP*AP*AP*AP*AP*UP*CP*CP*CP*
molecule tags Lyase/rna
source organism Escherichia coli
total genus 54
structure length 217
sequence length 217
chains with identical sequence B, C, D
ec nomenclature ec 5.4.99.28: tRNA pseudouridine(32) synthase.
pdb deposition date 2006-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2i82A00
3HJWA 1V9KA 3U28A 3LWOA 1SGVA 1ZL3A 3LWQA 3LWRA 1QYUA 1KSLA 2RFKA 4LABA 3MQKA 3HJYA 1ZE2A 1KSVA 4LGTA 2HVYA 1V9FA 3DH3A 3LWVA 2APOA 1R3EA 1PRZA 3UAIA 1ZE1A 1XPIA 2AB4A 1R3FA 2EY4A 2I82A 3LWPA 1KSKA 1K8WA 2ISTA 2AUSA 3HAXA
chains in the Genus database with same CATH superfamily
3HJWA 1V9KA 3U28A 3LWOA 1SGVA 1ZL3A 3LWQA 1SB7A 3LWRA 1QYUA 1SI7A 1KSLA 2RFKA 4LABA 3MQKA 3HJYA 1ZE2A 1KSVA 4LGTA 2HVYA 1V9FA 3DH3A 3LWVA 2APOA 1R3EA 1PRZA 1SZWA 3UAIA 1ZE1A 1Z2ZA 1XPIA 2AB4A 1R3FA 2EY4A 2I82A 3LWPA 1KSKA 1K8WA 2ISTA 2AUSA 3HAXA
chains in the Genus database with same CATH topology
3HJWA 1V9KA 3U28A 3LWOA 1SGVA 1ZL3A 3LWQA 1SB7A 3LWRA 1QYUA 1SI7A 1KSLA 2RFKA 4LABA 3MQKA 3HJYA 1ZE2A 1KSVA 4LGTA 2HVYA 1V9FA 3DH3A 3LWVA 2APOA 1R3EA 1PRZA 1SZWA 3UAIA 1ZE1A 1Z2ZA 1XPIA 2AB4A 1R3FA 2EY4A 2I82A 3LWPA 1KSKA 1K8WA 2ISTA 2AUSA 3HAXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HJW A;  1V9K A;  3U28 A;  3LWO A;  1SGV A;  1ZL3 A;  3LWQ A;  3LWR A;  1QYU A;  1KSL A;  2RFK A;  4LAB A;  3MQK A;  3HJY A;  1ZE2 A;  1KSV A;  4LGT A;  2HVY A;  1V9F A;  3DH3 A;  3LWV A;  2APO A;  1R3E A;  1PRZ A;  3UAI A;  1ZE1 A;  1XPI A;  2AB4 A;  1R3F A;  2EY4 A;  2I82 A;  3LWP A;  1KSK A;  1K8W A;  2IST A;  2AUS A;  3HAX A; 
#chains in the Genus database with same CATH topology
 3HJW A;  1V9K A;  3U28 A;  3LWO A;  1SGV A;  1ZL3 A;  3LWQ A;  1SB7 A;  3LWR A;  1QYU A;  1SI7 A;  1KSL A;  2RFK A;  4LAB A;  3MQK A;  3HJY A;  1ZE2 A;  1KSV A;  4LGT A;  2HVY A;  1V9F A;  3DH3 A;  3LWV A;  2APO A;  1R3E A;  1PRZ A;  1SZW A;  3UAI A;  1ZE1 A;  1Z2Z A;  1XPI A;  2AB4 A;  1R3F A;  2EY4 A;  2I82 A;  3LWP A;  1KSK A;  1K8W A;  2IST A;  2AUS A;  3HAX A; 
#chains in the Genus database with same CATH homology
 3HJW A;  1V9K A;  3U28 A;  3LWO A;  1SGV A;  1ZL3 A;  3LWQ A;  1SB7 A;  3LWR A;  1QYU A;  1SI7 A;  1KSL A;  2RFK A;  4LAB A;  3MQK A;  3HJY A;  1ZE2 A;  1KSV A;  4LGT A;  2HVY A;  1V9F A;  3DH3 A;  3LWV A;  2APO A;  1R3E A;  1PRZ A;  1SZW A;  3UAI A;  1ZE1 A;  1Z2Z A;  1XPI A;  2AB4 A;  1R3F A;  2EY4 A;  2I82 A;  3LWP A;  1KSK A;  1K8W A;  2IST A;  2AUS A;  3HAX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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