2RFKA

Substrate rna positioning in the archaeal h/aca ribonucleoprotein complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
334
structure length
334
Chain Sequence
EVRRILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLAPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWEKRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex.
pubmed doi rcsb
molecule tags Isomerase/rna
source organism Pyrococcus furiosus
molecule keywords guide RNA 1
total genus 73
structure length 334
sequence length 334
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2007-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2rfkA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2rfkA02
2AB4A 3DH3A 3U28A 1KSLA 1K8WA 2EY4A 1R3EA 2HVYA 3LWPA 3HAXA 4LGTA 1KSKA 3HJYA 3LWRA 1QYUA 1V9KA 3UAIA 2ISTA 4LABA 2I82A 1PRZA 2APOA 3ZV0C 2AUSA 1ZE2A 3MQKA 1ZE1A 1SGVA 1ZL3A 3LWOA 1V9FA 3LWVA 2RFKA 1R3FA 3LWQA 3HJWA 1KSVA 1XPIA
chains in the Genus database with same CATH superfamily
4TZ4C 4CI3B 1XNEA 1SQWA 3U28A 2DP9A 3LWPA 1T5YA 2CWWA 4LGTA 3M65A 3M6XA 3LWRA 4Q1TA 1WXWA 2I82A 3LDFA 2J5VA 1WK2A 4CI2B 1J2BA 3D79A 3LWVA 3LWQA 3C0KA 2EY4A 1R3EA 1WXXA 3HAXA 1ZS7A 1KSKA 4CI1B 1Z2ZA 1IT7A 1V9KA 4LABA 3ZV0C 2AUSA 2P38A 1IQ8A 1ZE1A 1ZL3A 3MQKA 3IUWA 2FRXA 3M4XA 1KSVA 1XPIA 1Q7HA 3LJCA 2AB4A 3DH3A 1K8WA 2J5TA 2ANEA 1UOYA 3M6UA 2HVYA 2B78A 2E5OA 3UAIA 1ZBOA 2ISTA 1PRZA 3LWOA 1V9FA 1SZWA 1SB7A 1R3FA 2RFKA 2AS0A 3M6WA 2Z0TA 2CX0A 1KSLA 3M6VA 2Q07A 2KKUA 1S04A 3HJYA 1QYUA 1TE7A 2APOA 1ZE2A 2CX1A 3VSEA 1SGVA 4DMGA 1SI7A 1IT8A 3HJWA
chains in the Genus database with same CATH topology
2AB4A 3DH3A 3U28A 1KSLA 1K8WA 2EY4A 3M6VA 1R3EA 1UOYA 3M6UA 2HVYA 3LWPA 3HAXA 4LGTA 1KSKA 3M6XA 3HJYA 1Z2ZA 3LWRA 1QYUA 1V9KA 3UAIA 3HJWA 2ISTA 4LABA 2I82A 1PRZA 2APOA 3ZV0C 2AUSA 1ZE2A 3MQKA 1ZE1A 1SGVA 1ZL3A 3LWOA 1V9FA 1SI7A 1SZWA 1SB7A 3LWVA 2RFKA 2FRXA 3LWQA 1R3FA 3M6WA 3M4XA 1KSVA 1XPIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AB4 A;  3DH3 A;  3U28 A;  1KSL A;  1K8W A;  2EY4 A;  1R3E A;  2HVY A;  3LWP A;  3HAX A;  4LGT A;  1KSK A;  3HJY A;  3LWR A;  1QYU A;  1V9K A;  3UAI A;  2IST A;  4LAB A;  2I82 A;  1PRZ A;  2APO A;  3ZV0 C;  2AUS A;  1ZE2 A;  3MQK A;  1ZE1 A;  1SGV A;  1ZL3 A;  3LWO A;  1V9F A;  3LWV A;  2RFK A;  1R3F A;  3LWQ A;  3HJW A;  1KSV A;  1XPI A; 
#chains in the Genus database with same CATH topology
 4TZ4 C;  4CI3 B;  1XNE A;  1SQW A;  3U28 A;  2DP9 A;  3LWP A;  1T5Y A;  2CWW A;  4LGT A;  3M65 A;  3M6X A;  3LWR A;  4Q1T A;  1WXW A;  2I82 A;  3LDF A;  2J5V A;  1WK2 A;  4CI2 B;  1J2B A;  3D79 A;  3LWV A;  3LWQ A;  3C0K A;  2EY4 A;  1R3E A;  1WXX A;  3HAX A;  1ZS7 A;  1KSK A;  4CI1 B;  1Z2Z A;  1IT7 A;  1V9K A;  4LAB A;  3ZV0 C;  2AUS A;  2P38 A;  1IQ8 A;  1ZE1 A;  1ZL3 A;  3MQK A;  3IUW A;  2FRX A;  3M4X A;  1KSV A;  1XPI A;  1Q7H A;  3LJC A;  2AB4 A;  3DH3 A;  1K8W A;  2J5T A;  2ANE A;  1UOY A;  3M6U A;  2HVY A;  2B78 A;  2E5O A;  3UAI A;  1ZBO A;  2IST A;  1PRZ A;  3LWO A;  1V9F A;  1SZW A;  1SB7 A;  1R3F A;  2RFK A;  2AS0 A;  3M6W A;  2Z0T A;  2CX0 A;  1KSL A;  3M6V A;  2Q07 A;  2KKU A;  1S04 A;  3HJY A;  1QYU A;  1TE7 A;  2APO A;  1ZE2 A;  2CX1 A;  3VSE A;  1SGV A;  4DMG A;  1SI7 A;  1IT8 A;  3HJW A; 
#chains in the Genus database with same CATH homology
 2AB4 A;  3DH3 A;  3U28 A;  1KSL A;  1K8W A;  2EY4 A;  3M6V A;  1R3E A;  1UOY A;  3M6U A;  2HVY A;  3LWP A;  3HAX A;  4LGT A;  1KSK A;  3M6X A;  3HJY A;  1Z2Z A;  3LWR A;  1QYU A;  1V9K A;  3UAI A;  3HJW A;  2IST A;  4LAB A;  2I82 A;  1PRZ A;  2APO A;  3ZV0 C;  2AUS A;  1ZE2 A;  3MQK A;  1ZE1 A;  1SGV A;  1ZL3 A;  3LWO A;  1V9F A;  1SI7 A;  1SZW A;  1SB7 A;  3LWV A;  2RFK A;  2FRX A;  3LWQ A;  1R3F A;  3M6W A;  3M4X A;  1KSV A;  1XPI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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