1ZE2A

Conformational change of pseudouridine 55 synthase upon its association with rna substrate
Total Genus 75
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
308
structure length
300
Chain Sequence
MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFRQERVLTLRKVFQT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords 5'-R(*GP*GP*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP
publication title Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase/rna
total genus 75
structure length 300
sequence length 308
chains with identical sequence B
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1ze2A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1ze2A01
3HJWA 3LWPA 1WXXA 2AS0A 1XPIA 4DMGA 3C0KA 3LWQA 2J5TA 2I82A 3DH3A 1IT8A 1QYUA 1ZE1A 3UAIA 1R3FA 3LWVA 1WXWA 1J2BA 2AUSA 1KSKA 1V9KA 1ZE2A 2J5VA 3LWOA 3LWRA 3LDFA 1KSVA 4Q1TA 1T5YA 1ZS7A 2RFKA 1IQ8A 2P38A 1SQWA 1K8WA 3VSEA 2ISTA 3HAXA 2HVYA 1V9FA 4LGTA 3D79A 3U28A 1IT7A 2CX1A 2AB4A 1PRZA 3HJYA 2CX0A 2B78A 2CWWA 1R3EA 1KSLA 2EY4A 3MQKA 2APOA 4LABA 1SGVA 1ZL3A 2Q07A 1Q7HA
chains in the Genus database with same CATH superfamily
2AS0A 2J5TA 1SZWA 1QYUA 1ZE1A 3M65A 3LWVA 1V9KA 1KSVA 1SI7A 2FRXA 3ZV0C 3HAXA 2HVYA 2CX1A 4TZ4C 2CX0A 3LJCA 2B78A 2KKUA 2EY4A 3MQKA 3M6WA 3LDFA 1ZL3A 3M6VA 3HJWA 2E5OA 2DP9A 1ZE2A 2J5VA 2P38A 4CI2B 3VSEA 2ISTA 1V9FA 1IT7A 4CI3B 2AB4A 3HJYA 1XNEA 1R3EA 1UOYA 2Q07A 3LWPA 1XPIA 4DMGA 3C0KA 3M6XA 2Z0TA 2I82A 3DH3A 3IUWA 1IT8A 3UAIA 1WXWA 1J2BA 1S04A 1KSKA 3LWOA 3LWRA 1Z2ZA 4Q1TA 1T5YA 2ANEA 1ZS7A 2RFKA 3M4XA 4LGTA 3D79A 1PRZA 1WK2A 2CWWA 1ZBOA 1KSLA 2APOA 4LABA 1Q7HA 1WXXA 3LWQA 4CI1B 1R3FA 2AUSA 1TE7A 1SB7A 1IQ8A 1SQWA 1K8WA 3U28A 3M6UA 1SGVA
chains in the Genus database with same CATH topology
3HJWA 3LWPA 1WXXA 2AS0A 1XPIA 4DMGA 3C0KA 3LWQA 2J5TA 1SZWA 2I82A 3DH3A 1IT8A 1QYUA 1ZE1A 3UAIA 1R3FA 3LWVA 1WXWA 1J2BA 2AUSA 1KSKA 1SB7A 1V9KA 1ZE2A 2J5VA 3LWOA 3LWRA 3LDFA 1KSVA 1Z2ZA 4Q1TA 1SI7A 1T5YA 1ZS7A 2RFKA 1IQ8A 2P38A 1SQWA 1K8WA 3VSEA 2ISTA 3HAXA 2HVYA 1V9FA 4LGTA 3D79A 3U28A 1IT7A 2CX1A 2AB4A 1PRZA 3HJYA 2CX0A 2B78A 2CWWA 1R3EA 1KSLA 2EY4A 3MQKA 2APOA 4LABA 1SGVA 1ZL3A 2Q07A 1Q7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HJW A;  3LWP A;  1WXX A;  2AS0 A;  1XPI A;  4DMG A;  3C0K A;  3LWQ A;  2J5T A;  2I82 A;  3DH3 A;  1IT8 A;  1QYU A;  1ZE1 A;  3UAI A;  1R3F A;  3LWV A;  1WXW A;  1J2B A;  2AUS A;  1KSK A;  1V9K A;  1ZE2 A;  2J5V A;  3LWO A;  3LWR A;  3LDF A;  1KSV A;  4Q1T A;  1T5Y A;  1ZS7 A;  2RFK A;  1IQ8 A;  2P38 A;  1SQW A;  1K8W A;  3VSE A;  2IST A;  3HAX A;  2HVY A;  1V9F A;  4LGT A;  3D79 A;  3U28 A;  1IT7 A;  2CX1 A;  2AB4 A;  1PRZ A;  3HJY A;  2CX0 A;  2B78 A;  2CWW A;  1R3E A;  1KSL A;  2EY4 A;  3MQK A;  2APO A;  4LAB A;  1SGV A;  1ZL3 A;  2Q07 A;  1Q7H A; 
#chains in the Genus database with same CATH topology
 2AS0 A;  2J5T A;  1SZW A;  1QYU A;  1ZE1 A;  3M65 A;  3LWV A;  1V9K A;  1KSV A;  1SI7 A;  2FRX A;  3ZV0 C;  3HAX A;  2HVY A;  2CX1 A;  4TZ4 C;  2CX0 A;  3LJC A;  2B78 A;  2KKU A;  2EY4 A;  3MQK A;  3M6W A;  3LDF A;  1ZL3 A;  3M6V A;  3HJW A;  2E5O A;  2DP9 A;  1ZE2 A;  2J5V A;  2P38 A;  4CI2 B;  3VSE A;  2IST A;  1V9F A;  1IT7 A;  4CI3 B;  2AB4 A;  3HJY A;  1XNE A;  1R3E A;  1UOY A;  2Q07 A;  3LWP A;  1XPI A;  4DMG A;  3C0K A;  3M6X A;  2Z0T A;  2I82 A;  3DH3 A;  3IUW A;  1IT8 A;  3UAI A;  1WXW A;  1J2B A;  1S04 A;  1KSK A;  3LWO A;  3LWR A;  1Z2Z A;  4Q1T A;  1T5Y A;  2ANE A;  1ZS7 A;  2RFK A;  3M4X A;  4LGT A;  3D79 A;  1PRZ A;  1WK2 A;  2CWW A;  1ZBO A;  1KSL A;  2APO A;  4LAB A;  1Q7H A;  1WXX A;  3LWQ A;  4CI1 B;  1R3F A;  2AUS A;  1TE7 A;  1SB7 A;  1IQ8 A;  1SQW A;  1K8W A;  3U28 A;  3M6U A;  1SGV A; 
#chains in the Genus database with same CATH homology
 3HJW A;  3LWP A;  1WXX A;  2AS0 A;  1XPI A;  4DMG A;  3C0K A;  3LWQ A;  2J5T A;  1SZW A;  2I82 A;  3DH3 A;  1IT8 A;  1QYU A;  1ZE1 A;  3UAI A;  1R3F A;  3LWV A;  1WXW A;  1J2B A;  2AUS A;  1KSK A;  1SB7 A;  1V9K A;  1ZE2 A;  2J5V A;  3LWO A;  3LWR A;  3LDF A;  1KSV A;  1Z2Z A;  4Q1T A;  1SI7 A;  1T5Y A;  1ZS7 A;  2RFK A;  1IQ8 A;  2P38 A;  1SQW A;  1K8W A;  3VSE A;  2IST A;  3HAX A;  2HVY A;  1V9F A;  4LGT A;  3D79 A;  3U28 A;  1IT7 A;  2CX1 A;  2AB4 A;  1PRZ A;  3HJY A;  2CX0 A;  2B78 A;  2CWW A;  1R3E A;  1KSL A;  2EY4 A;  3MQK A;  2APO A;  4LAB A;  1SGV A;  1ZL3 A;  2Q07 A;  1Q7H A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...