1ZL3A

Coupling of active site motions and rna binding
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
302
structure length
302
Chain Sequence
MDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALNPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase/rna
molecule keywords 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*
publication title Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
pubmed doi rcsb
source organism Escherichia coli
total genus 80
structure length 302
sequence length 302
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF09157 TruB-C_2 Pseudouridine synthase II TruB, C-terminal
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1zl3A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1zl3A01
2RFKA 2HVYA 1XPIA 3HJWA 3MQKA 1ZE2A 1KSLA 4DMGA 1KSVA 2J5TA 2P38A 2CX1A 1R3EA 3C0KA 2APOA 2I82A 3LWRA 1KSKA 1J2BA 1ZS7A 3VSEA 1IT8A 1K8WA 1Q7HA 3U28A 2AS0A 1IQ8A 1ZE1A 2J5VA 3D79A 1V9KA 2AUSA 3DH3A 3LWPA 3UAIA 2Q07A 1QYUA 4LGTA 1WXXA 2B78A 1T5YA 2CWWA 2AB4A 2EY4A 1WXWA 4LABA 3LDFA 4Q1TA 2ISTA 3LWOA 3LWQA 1SGVA 1IT7A 3HAXA 3HJYA 2CX0A 1PRZA 1V9FA 1SQWA 1ZL3A 3LWVA 1R3FA
chains in the Genus database with same CATH superfamily
3HJWA 1KSVA 1TE7A 2CX1A 3M4XA 2Q07A 1QYUA 3M6VA 4CI2B 3M6XA 1SI7A 1UOYA 3LWVA 3MQKA 1ZE2A 2Z0TA 1KSLA 1R3EA 1WK2A 3VSEA 2ANEA 1Q7HA 2J5VA 3UAIA 1WXXA 2AB4A 3IUWA 3LDFA 2ISTA 1IT7A 4CI3B 3HAXA 1Z2ZA 1SQWA 1ZL3A 1R3FA 2RFKA 4DMGA 2J5TA 2P38A 1XNEA 3C0KA 2I82A 3LWRA 3M6UA 1ZBOA 1J2BA 1ZS7A 1IT8A 1K8WA 3U28A 2AUSA 1V9KA 3LWPA 2DP9A 2E5OA 2B78A 2CWWA 1SZWA 4Q1TA 3LWOA 3HJYA 3LWQA 1SGVA 2CX0A 1PRZA 1S04A 2HVYA 1XPIA 2KKUA 2APOA 1KSKA 3M6WA 2AS0A 1IQ8A 3M65A 1ZE1A 3D79A 4CI1B 3DH3A 3LJCA 3ZV0C 4TZ4C 4LGTA 1T5YA 2EY4A 1SB7A 1WXWA 2FRXA 4LABA 1V9FA
chains in the Genus database with same CATH topology
2RFKA 2HVYA 1XPIA 3HJWA 3MQKA 1ZE2A 1KSLA 4DMGA 1KSVA 2J5TA 2P38A 2CX1A 1R3EA 3C0KA 2APOA 2I82A 3LWRA 1KSKA 1J2BA 1ZS7A 3VSEA 1IT8A 1K8WA 1Q7HA 3U28A 2AS0A 1IQ8A 1ZE1A 2J5VA 3D79A 1V9KA 2AUSA 3DH3A 3LWPA 3UAIA 2Q07A 1QYUA 4LGTA 1WXXA 2B78A 1T5YA 2CWWA 2AB4A 1SB7A 2EY4A 1WXWA 1SZWA 4LABA 3LDFA 4Q1TA 2ISTA 3LWOA 3LWQA 1SGVA 1IT7A 3HAXA 1SI7A 2CX0A 3HJYA 1PRZA 1V9FA 1Z2ZA 1SQWA 1ZL3A 3LWVA 1R3FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RFK A;  2HVY A;  1XPI A;  3HJW A;  3MQK A;  1ZE2 A;  1KSL A;  4DMG A;  1KSV A;  2J5T A;  2P38 A;  2CX1 A;  1R3E A;  3C0K A;  2APO A;  2I82 A;  3LWR A;  1KSK A;  1J2B A;  1ZS7 A;  3VSE A;  1IT8 A;  1K8W A;  1Q7H A;  3U28 A;  2AS0 A;  1IQ8 A;  1ZE1 A;  2J5V A;  3D79 A;  1V9K A;  2AUS A;  3DH3 A;  3LWP A;  3UAI A;  2Q07 A;  1QYU A;  4LGT A;  1WXX A;  2B78 A;  1T5Y A;  2CWW A;  2AB4 A;  2EY4 A;  1WXW A;  4LAB A;  3LDF A;  4Q1T A;  2IST A;  3LWO A;  3LWQ A;  1SGV A;  1IT7 A;  3HAX A;  3HJY A;  2CX0 A;  1PRZ A;  1V9F A;  1SQW A;  1ZL3 A;  3LWV A;  1R3F A; 
#chains in the Genus database with same CATH topology
 3HJW A;  1KSV A;  1TE7 A;  2CX1 A;  3M4X A;  2Q07 A;  1QYU A;  3M6V A;  4CI2 B;  3M6X A;  1SI7 A;  1UOY A;  3LWV A;  3MQK A;  1ZE2 A;  2Z0T A;  1KSL A;  1R3E A;  1WK2 A;  3VSE A;  2ANE A;  1Q7H A;  2J5V A;  3UAI A;  1WXX A;  2AB4 A;  3IUW A;  3LDF A;  2IST A;  1IT7 A;  4CI3 B;  3HAX A;  1Z2Z A;  1SQW A;  1ZL3 A;  1R3F A;  2RFK A;  4DMG A;  2J5T A;  2P38 A;  1XNE A;  3C0K A;  2I82 A;  3LWR A;  3M6U A;  1ZBO A;  1J2B A;  1ZS7 A;  1IT8 A;  1K8W A;  3U28 A;  2AUS A;  1V9K A;  3LWP A;  2DP9 A;  2E5O A;  2B78 A;  2CWW A;  1SZW A;  4Q1T A;  3LWO A;  3HJY A;  3LWQ A;  1SGV A;  2CX0 A;  1PRZ A;  1S04 A;  2HVY A;  1XPI A;  2KKU A;  2APO A;  1KSK A;  3M6W A;  2AS0 A;  1IQ8 A;  3M65 A;  1ZE1 A;  3D79 A;  4CI1 B;  3DH3 A;  3LJC A;  3ZV0 C;  4TZ4 C;  4LGT A;  1T5Y A;  2EY4 A;  1SB7 A;  1WXW A;  2FRX A;  4LAB A;  1V9F A; 
#chains in the Genus database with same CATH homology
 2RFK A;  2HVY A;  1XPI A;  3HJW A;  3MQK A;  1ZE2 A;  1KSL A;  4DMG A;  1KSV A;  2J5T A;  2P38 A;  2CX1 A;  1R3E A;  3C0K A;  2APO A;  2I82 A;  3LWR A;  1KSK A;  1J2B A;  1ZS7 A;  3VSE A;  1IT8 A;  1K8W A;  1Q7H A;  3U28 A;  2AS0 A;  1IQ8 A;  1ZE1 A;  2J5V A;  3D79 A;  1V9K A;  2AUS A;  3DH3 A;  3LWP A;  3UAI A;  2Q07 A;  1QYU A;  4LGT A;  1WXX A;  2B78 A;  1T5Y A;  2CWW A;  2AB4 A;  1SB7 A;  2EY4 A;  1WXW A;  1SZW A;  4LAB A;  3LDF A;  4Q1T A;  2IST A;  3LWO A;  3LWQ A;  1SGV A;  1IT7 A;  3HAX A;  1SI7 A;  2CX0 A;  3HJY A;  1PRZ A;  1V9F A;  1Z2Z A;  1SQW A;  1ZL3 A;  3LWV A;  1R3F A; 
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