1ZL3A

Coupling of active site motions and rna binding
Total Genus 80
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
302
structure length
302
Chain Sequence
MDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALNPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*
publication title Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase/rna
total genus 80
structure length 302
sequence length 302
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF09157 TruB-C_2 Pseudouridine synthase II TruB, C-terminal
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1zl3A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1zl3A01
1IT7A 4DMGA 1J2BA 1Q7HA 3LWPA 1V9KA 2ISTA 1IQ8A 2CX0A 1PRZA 3LWVA 3C0KA 1ZE2A 3UAIA 3U28A 1ZS7A 2P38A 3LDFA 1SGVA 2AS0A 1T5YA 3LWOA 2Q07A 2CX1A 2AUSA 1R3EA 2J5VA 2AB4A 2CWWA 3D79A 3LWRA 4LGTA 2B78A 4LABA 1V9FA 3MQKA 3HAXA 2RFKA 4Q1TA 1KSVA 2I82A 1IT8A 2J5TA 1WXWA 1WXXA 3VSEA 3HJYA 3LWQA 2EY4A 1SQWA 1KSKA 1KSLA 1ZE1A 1R3FA 1K8WA 1QYUA 1XPIA 2HVYA 2APOA 3DH3A 3HJWA 1ZL3A
chains in the Genus database with same CATH superfamily
4DMGA 1J2BA 1V9KA 2ANEA 3IUWA 3ZV0C 2Z0TA 3LJCA 1Z2ZA 2CX1A 1R3EA 2J5VA 2CWWA 3LWRA 3MQKA 3M6WA 1SB7A 1QYUA 3M6VA 1XPIA 3HJWA 1IT7A 3LWPA 1PRZA 3UAIA 4CI2B 1S04A 2P38A 3LDFA 4TZ4C 1UOYA 4LGTA 4LABA 1KSVA 3VSEA 3HJYA 3LWQA 2EY4A 1SQWA 4CI1B 1R3FA 1K8WA 3DH3A 1SI7A 2E5OA 1Q7HA 2CX0A 3LWVA 3C0KA 3U28A 4CI3B 2AS0A 2Q07A 2FRXA 2KKUA 3HAXA 2RFKA 4Q1TA 2J5TA 1SZWA 3M4XA 1KSLA 2HVYA 2APOA 1TE7A 2AUSA 2ISTA 1IQ8A 3M6UA 1XNEA 1ZE2A 3M6XA 1ZS7A 1SGVA 1T5YA 3LWOA 2AB4A 3D79A 2B78A 1V9FA 1WK2A 1ZBOA 2I82A 1IT8A 1WXWA 1WXXA 2DP9A 3M65A 1KSKA 1ZE1A 1ZL3A
chains in the Genus database with same CATH topology
1IT7A 4DMGA 1J2BA 1Q7HA 3LWPA 3HJWA 1V9KA 2ISTA 1IQ8A 2CX0A 1PRZA 3LWVA 3C0KA 1ZE2A 3UAIA 3U28A 1ZS7A 2P38A 3LDFA 1SGVA 2AS0A 1T5YA 3LWOA 2Q07A 2CX1A 1Z2ZA 2AUSA 1R3EA 2J5VA 2AB4A 2CWWA 3D79A 3LWRA 4LGTA 2B78A 4LABA 1V9FA 3MQKA 3HAXA 2RFKA 4Q1TA 1KSVA 2I82A 1IT8A 2J5TA 1WXWA 1WXXA 3VSEA 3HJYA 3LWQA 2EY4A 1SQWA 1KSKA 1KSLA 1SZWA 1SB7A 1ZE1A 1R3FA 1K8WA 1QYUA 1XPIA 2HVYA 2APOA 3DH3A 1SI7A 1ZL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IT7 A;  4DMG A;  1J2B A;  1Q7H A;  3LWP A;  1V9K A;  2IST A;  1IQ8 A;  2CX0 A;  1PRZ A;  3LWV A;  3C0K A;  1ZE2 A;  3UAI A;  3U28 A;  1ZS7 A;  2P38 A;  3LDF A;  1SGV A;  2AS0 A;  1T5Y A;  3LWO A;  2Q07 A;  2CX1 A;  2AUS A;  1R3E A;  2J5V A;  2AB4 A;  2CWW A;  3D79 A;  3LWR A;  4LGT A;  2B78 A;  4LAB A;  1V9F A;  3MQK A;  3HAX A;  2RFK A;  4Q1T A;  1KSV A;  2I82 A;  1IT8 A;  2J5T A;  1WXW A;  1WXX A;  3VSE A;  3HJY A;  3LWQ A;  2EY4 A;  1SQW A;  1KSK A;  1KSL A;  1ZE1 A;  1R3F A;  1K8W A;  1QYU A;  1XPI A;  2HVY A;  2APO A;  3DH3 A;  3HJW A;  1ZL3 A; 
#chains in the Genus database with same CATH topology
 4DMG A;  1J2B A;  1V9K A;  2ANE A;  3IUW A;  3ZV0 C;  2Z0T A;  3LJC A;  1Z2Z A;  2CX1 A;  1R3E A;  2J5V A;  2CWW A;  3LWR A;  3MQK A;  3M6W A;  1SB7 A;  1QYU A;  3M6V A;  1XPI A;  3HJW A;  1IT7 A;  3LWP A;  1PRZ A;  3UAI A;  4CI2 B;  1S04 A;  2P38 A;  3LDF A;  4TZ4 C;  1UOY A;  4LGT A;  4LAB A;  1KSV A;  3VSE A;  3HJY A;  3LWQ A;  2EY4 A;  1SQW A;  4CI1 B;  1R3F A;  1K8W A;  3DH3 A;  1SI7 A;  2E5O A;  1Q7H A;  2CX0 A;  3LWV A;  3C0K A;  3U28 A;  4CI3 B;  2AS0 A;  2Q07 A;  2FRX A;  2KKU A;  3HAX A;  2RFK A;  4Q1T A;  2J5T A;  1SZW A;  3M4X A;  1KSL A;  2HVY A;  2APO A;  1TE7 A;  2AUS A;  2IST A;  1IQ8 A;  3M6U A;  1XNE A;  1ZE2 A;  3M6X A;  1ZS7 A;  1SGV A;  1T5Y A;  3LWO A;  2AB4 A;  3D79 A;  2B78 A;  1V9F A;  1WK2 A;  1ZBO A;  2I82 A;  1IT8 A;  1WXW A;  1WXX A;  2DP9 A;  3M65 A;  1KSK A;  1ZE1 A;  1ZL3 A; 
#chains in the Genus database with same CATH homology
 1IT7 A;  4DMG A;  1J2B A;  1Q7H A;  3LWP A;  3HJW A;  1V9K A;  2IST A;  1IQ8 A;  2CX0 A;  1PRZ A;  3LWV A;  3C0K A;  1ZE2 A;  3UAI A;  3U28 A;  1ZS7 A;  2P38 A;  3LDF A;  1SGV A;  2AS0 A;  1T5Y A;  3LWO A;  2Q07 A;  2CX1 A;  1Z2Z A;  2AUS A;  1R3E A;  2J5V A;  2AB4 A;  2CWW A;  3D79 A;  3LWR A;  4LGT A;  2B78 A;  4LAB A;  1V9F A;  3MQK A;  3HAX A;  2RFK A;  4Q1T A;  1KSV A;  2I82 A;  1IT8 A;  2J5T A;  1WXW A;  1WXX A;  3VSE A;  3HJY A;  3LWQ A;  2EY4 A;  1SQW A;  1KSK A;  1KSL A;  1SZW A;  1SB7 A;  1ZE1 A;  1R3F A;  1K8W A;  1QYU A;  1XPI A;  2HVY A;  2APO A;  3DH3 A;  1SI7 A;  1ZL3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...