1EOF | Genus

Total Genus 35

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	35
sequence length	100
structure length	100
Chain Sequence	ERVVINVSGLRFETQLKTLNQFPDTLLGNPQKRNRYYDPLRNEYFFDRNRPSFDAILYFYQSGGRLRRPVAVPLDVFSEEIKFYELGENAFERYREDEGF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Membrane protein
source organism	Aplysia californica
publication title	Voltage dependent activation of potassium channels is coupled to T1 domain structure. pubmed doi rcsb
molecule keywords	POTASSIUM CHANNEL KV1.1
total genus	35
structure length	100
sequence length	100
ec nomenclature
pdb deposition date	2000-03-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02214	BTB_2	BTB/POZ domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	1eofA00

2IZVC 2R9RB 4U2MA 1A68A 3L2OA 1EOFA 4JTAB 4B9KB 4U77A 3KVTA 3V7DA 3B84A 1EXBE 2OVQA 1QDVA 4APFA 4BGCA 3ZUNB 4JGHC 1FS2B 5BXDA 1P22B 2NN2A 1T1DA 5A6RA 3DCGB 4W9IB 3FKCA 1LQBB 4W9KB 3E4UA 3HTMA 4EOZA 5JH5B 2MA9C 3ZTCB 3LBZA 4W9LB 2OVPA 2IHCA 5DADA 3HQIA 2P1QA 3DRZA 4W9HH 4CXTA 4W9HB 3M52A 1VCBB 3OHUA 4JTCB 4W9GB 3HVEA 1NEXA 3M8VA 4U2NA 5BXHA 3ZRFB 3MKSA 3M4TA 4AJYC 1LM8C 2E32B 1S1GA 2I2RA 1BUOA 5HYWB 4UYIA 1QDWA 4W9EB 5H7GA 5BXBA 4J8ZA 3ZNGB 4HXIA 1HV2A 5EUPA 5HZGC 2YY9A 2ASTA 2E31B 4WQOC 2JZ3C 2Z8HA 3BIMA 4W9FB 1EOEA 2VKPA 1R2BA 5BO4C 4ZOUA 3OHVA 2IF5A 2P1MA 3GA1A 4B9KE 2OVRA 2P1OA 3C6PA 4W9JB 5FTAA 2C9WC 2Q81A 2VPKA 3I3NA 1DSXA 4W9DB 1LDKD 2ASSA 4JTDB 2PPIA 1CS3A 3C6NA 3OGKA 4CRHA 5A15A 3ZKJB 4CP3A 4CXIA 1NN7A 3HVEB 3M5BA 3HU6A 1EODA 3OGMA 1FQVB 2A79B 3LUTB 3ZRCB 4BKSB 4UIJA 1R29A 2P1PA 4N9F5 4AP2A 5IBKA 3ZTDB 5H7HA 1FS1B 3LNMB 4W9CB 2NZ0B 4AWJB 1R28A 2FNJC 4CXJA 5LLIB 4BKTB 5DAFA 3C6OA 3WSOB 4I6JC 3OGLA 2P1NA 4B95B
chains in the Genus database with same CATH superfamily

2IZVC 2R9RB 4U2MA 1A68A 3L2OA 1EOFA 4JTAB 4B9KB 4U77A 3KVTA 3V7DA 3B84A 3DRYA 1EXBE 2OVQA 1QDVA 4APFA 4BGCA 3ZUNB 4JGHC 1FS2B 5BXDA 1P22B 2NN2A 1T1DA 5A6RA 3DCGB 4W9IB 3FKCA 1LQBB 4W9KB 3E4UA 3HTMA 4EOZA 5JH5B 2MA9C 3ZTCB 3LBZA 4W9LB 2OVPA 2IHCA 5DADA 3HQIA 2P1QA 3DRZA 4W9HH 4CXTA 4W9HB 3M52A 1VCBB 3OHUA 4JTCB 4W9GB 3HVEA 1NEXA 3M8VA 4U2NA 5BXHA 3ZRFB 3MKSA 3M4TA 4AJYC 1LM8C 2E32B 1S1GA 2I2RA 1BUOA 5HYWB 4UYIA 1QDWA 4W9EB 5H7GA 5BXBA 4J8ZA 3ZNGB 3DRXA 4HXIA 1HV2A 5EUPA 5HZGC 2YY9A 2ASTA 2E31B 4WQOC 2JZ3C 2Z8HA 3BIMA 4W9FB 1EOEA 2VKPA 1R2BA 5BO4C 4ZOUA 3OHVA 2IF5A 2P1MA 4YY8A 3GA1A 4B9KE 2OVRA 2P1OA 3C6PA 4W9JB 5FTAA 4ZGCA 2C9WC 2Q81A 2VPKA 3I3NA 1DSXA 4W9DB 1LDKD 2ASSA 4JTDB 2PPIA 1CS3A 3C6NA 3OGKA 4CRHA 5A15A 3ZKJB 4CP3A 4CXIA 1NN7A 3HVEB 3M5BA 3HU6A 1EODA 3OGMA 1FQVB 2A79B 3LUTB 3ZRCB 4BKSB 4UIJA 1R29A 2P1PA 4N9F5 4AP2A 5IBKA 3ZTDB 5H7HA 1FS1B 3LNMB 4W9CB 2NZ0B 4AWJB 1R28A 2FNJC 4CXJA 5LLIB 4BKTB 5DAFA 3C6OA 3WSOB 4I6JC 3OGLA 2P1NA 4B95B
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2IZV C;  2R9R B;  4U2M A;  1A68 A;  3L2O A;  1EOF A;  4JTA B;  4B9K B;  4U77 A;  3KVT A;  3V7D A;  3B84 A;  1EXB E;  2OVQ A;  1QDV A;  4APF A;  4BGC A;  3ZUN B;  4JGH C;  1FS2 B;  5BXD A;  1P22 B;  2NN2 A;  1T1D A;  5A6R A;  3DCG B;  4W9I B;  3FKC A;  1LQB B;  4W9K B;  3E4U A;  3HTM A;  4EOZ A;  5JH5 B;  2MA9 C;  3ZTC B;  3LBZ A;  4W9L B;  2OVP A;  2IHC A;  5DAD A;  3HQI A;  2P1Q A;  3DRZ A;  4W9H H;  4CXT A;  4W9H B;  3M52 A;  1VCB B;  3OHU A;  4JTC B;  4W9G B;  3HVE A;  1NEX A;  3M8V A;  4U2N A;  5BXH A;  3ZRF B;  3MKS A;  3M4T A;  4AJY C;  1LM8 C;  2E32 B;  1S1G A;  2I2R A;  1BUO A;  5HYW B;  4UYI A;  1QDW A;  4W9E B;  5H7G A;  5BXB A;  4J8Z A;  3ZNG B;  4HXI A;  1HV2 A;  5EUP A;  5HZG C;  2YY9 A;  2AST A;  2E31 B;  4WQO C;  2JZ3 C;  2Z8H A;  3BIM A;  4W9F B;  1EOE A;  2VKP A;  1R2B A;  5BO4 C;  4ZOU A;  3OHV A;  2IF5 A;  2P1M A;  3GA1 A;  4B9K E;  2OVR A;  2P1O A;  3C6P A;  4W9J B;  5FTA A;  2C9W C;  2Q81 A;  2VPK A;  3I3N A;  1DSX A;  4W9D B;  1LDK D;  2ASS A;  4JTD B;  2PPI A;  1CS3 A;  3C6N A;  3OGK A;  4CRH A;  5A15 A;  3ZKJ B;  4CP3 A;  4CXI A;  1NN7 A;  3HVE B;  3M5B A;  3HU6 A;  1EOD A;  3OGM A;  1FQV B;  2A79 B;  3LUT B;  3ZRC B;  4BKS B;  4UIJ A;  1R29 A;  2P1P A;  4N9F 5;  4AP2 A;  5IBK A;  3ZTD B;  5H7H A;  1FS1 B;  3LNM B;  4W9C B;  2NZ0 B;  4AWJ B;  1R28 A;  2FNJ C;  4CXJ A;  5LLI B;  4BKT B;  5DAF A;  3C6O A;  3WSO B;  4I6J C;  3OGL A;  2P1N A;  4B95 B; 
#chains in the Genus database with same CATH topology
 2IZV C;  2R9R B;  4U2M A;  1A68 A;  3L2O A;  1EOF A;  4JTA B;  4B9K B;  4U77 A;  3KVT A;  3V7D A;  3B84 A;  3DRY A;  1EXB E;  2OVQ A;  1QDV A;  4APF A;  4BGC A;  3ZUN B;  4JGH C;  1FS2 B;  5BXD A;  1P22 B;  2NN2 A;  1T1D A;  5A6R A;  3DCG B;  4W9I B;  3FKC A;  1LQB B;  4W9K B;  3E4U A;  3HTM A;  4EOZ A;  5JH5 B;  2MA9 C;  3ZTC B;  3LBZ A;  4W9L B;  2OVP A;  2IHC A;  5DAD A;  3HQI A;  2P1Q A;  3DRZ A;  4W9H H;  4CXT A;  4W9H B;  3M52 A;  1VCB B;  3OHU A;  4JTC B;  4W9G B;  3HVE A;  1NEX A;  3M8V A;  4U2N A;  5BXH A;  3ZRF B;  3MKS A;  3M4T A;  4AJY C;  1LM8 C;  2E32 B;  1S1G A;  2I2R A;  1BUO A;  5HYW B;  4UYI A;  1QDW A;  4W9E B;  5H7G A;  5BXB A;  4J8Z A;  3ZNG B;  3DRX A;  4HXI A;  1HV2 A;  5EUP A;  5HZG C;  2YY9 A;  2AST A;  2E31 B;  4WQO C;  2JZ3 C;  2Z8H A;  3BIM A;  4W9F B;  1EOE A;  2VKP A;  1R2B A;  5BO4 C;  4ZOU A;  3OHV A;  2IF5 A;  2P1M A;  4YY8 A;  3GA1 A;  4B9K E;  2OVR A;  2P1O A;  3C6P A;  4W9J B;  5FTA A;  4ZGC A;  2C9W C;  2Q81 A;  2VPK A;  3I3N A;  1DSX A;  4W9D B;  1LDK D;  2ASS A;  4JTD B;  2PPI A;  1CS3 A;  3C6N A;  3OGK A;  4CRH A;  5A15 A;  3ZKJ B;  4CP3 A;  4CXI A;  1NN7 A;  3HVE B;  3M5B A;  3HU6 A;  1EOD A;  3OGM A;  1FQV B;  2A79 B;  3LUT B;  3ZRC B;  4BKS B;  4UIJ A;  1R29 A;  2P1P A;  4N9F 5;  4AP2 A;  5IBK A;  3ZTD B;  5H7H A;  1FS1 B;  3LNM B;  4W9C B;  2NZ0 B;  4AWJ B;  1R28 A;  2FNJ C;  4CXJ A;  5LLI B;  4BKT B;  5DAF A;  3C6O A;  3WSO B;  4I6J C;  3OGL A;  2P1N A;  4B95 B; 
#chains in the Genus database with same CATH homology
 2IZV C;  2R9R B;  4U2M A;  1A68 A;  3L2O A;  1EOF A;  4JTA B;  4B9K B;  4U77 A;  3KVT A;  3V7D A;  3B84 A;  3DRY A;  1EXB E;  2OVQ A;  1QDV A;  4APF A;  4BGC A;  3ZUN B;  4JGH C;  1FS2 B;  5BXD A;  1P22 B;  2NN2 A;  1T1D A;  5A6R A;  3DCG B;  4W9I B;  3FKC A;  1LQB B;  4W9K B;  3E4U A;  3HTM A;  4EOZ A;  5JH5 B;  2MA9 C;  3ZTC B;  3LBZ A;  4W9L B;  2OVP A;  2IHC A;  5DAD A;  3HQI A;  2P1Q A;  3DRZ A;  4W9H H;  4CXT A;  4W9H B;  3M52 A;  1VCB B;  3OHU A;  4JTC B;  4W9G B;  3HVE A;  1NEX A;  3M8V A;  4U2N A;  5BXH A;  3ZRF B;  3MKS A;  3M4T A;  4AJY C;  1LM8 C;  2E32 B;  1S1G A;  2I2R A;  1BUO A;  5HYW B;  4UYI A;  1QDW A;  4W9E B;  5H7G A;  5BXB A;  4J8Z A;  3ZNG B;  3DRX A;  4HXI A;  1HV2 A;  5EUP A;  5HZG C;  2YY9 A;  2AST A;  2E31 B;  4WQO C;  2JZ3 C;  2Z8H A;  3BIM A;  4W9F B;  1EOE A;  2VKP A;  1R2B A;  5BO4 C;  4ZOU A;  3OHV A;  2IF5 A;  2P1M A;  4YY8 A;  3GA1 A;  4B9K E;  2OVR A;  2P1O A;  3C6P A;  4W9J B;  5FTA A;  4ZGC A;  2C9W C;  2Q81 A;  2VPK A;  3I3N A;  1DSX A;  4W9D B;  1LDK D;  2ASS A;  4JTD B;  2PPI A;  1CS3 A;  3C6N A;  3OGK A;  4CRH A;  5A15 A;  3ZKJ B;  4CP3 A;  4CXI A;  1NN7 A;  3HVE B;  3M5B A;  3HU6 A;  1EOD A;  3OGM A;  1FQV B;  2A79 B;  3LUT B;  3ZRC B;  4BKS B;  4UIJ A;  1R29 A;  2P1P A;  4N9F 5;  4AP2 A;  5IBK A;  3ZTD B;  5H7H A;  1FS1 B;  3LNM B;  4W9C B;  2NZ0 B;  4AWJ B;  1R28 A;  2FNJ C;  4CXJ A;  5LLI B;  4BKT B;  5DAF A;  3C6O A;  3WSO B;  4I6J C;  3OGL A;  2P1N A;  4B95 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1EOFA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations