1FWMA

Crystal structure of the thymidylate synthase r166q mutant
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
263
structure length
263
Chain Sequence
KQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQQSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Escherichia coli
publication title Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity.
pubmed doi rcsb
molecule keywords THYMIDYLATE SYNTHASE
total genus 83
structure length 263
sequence length 263
chains with identical sequence B
ec nomenclature ec 2.1.1.45: Thymidylate synthase.
pdb deposition date 2000-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00303 Thymidylat_synt Thymidylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase; Chain A Thymidylate synthase/dCMP hydroxymethylase domain 1fwmA00
1F4BA 3ED7A 3HJ3A 1F28A 1JUJA 1TSZA 3N5GA 1KZJA 3BHRA 1TSXA 3GG5A 3BFIA 2RD8B 1NJDA 3DG8C 4E5OA 4ISKA 4O7UA 4GYHA 1TSNA 3C0AA 1NJBA 1BJGA 1BP0A 3IRNA 3HB8A 3GH0A 3K2HA 1JMFA 2H2QA 1JMHA 1I00A 3UM5A 2TSRA 4O1XD 3BGXA 4DPHA 2A9WA 5BY6A 4PSGA 1DDUA 1F4DA 1B5EA 4DPDA 3IK0A 1F4GA 2G89A 2G8XA 1JTQA 4KY4A 1BSPA 3EDWX 1J3JC 4FOXA 4E28A 3UWLA 3OB7A 1TSLA 1VZCA 2FTNA 2G8AA 1BIDA 1BPJA 1JMGA 1TISA 2KCEA 3HBBA 1QZFA 1TDAA 1LCBA 1DNAA 1NJEA 1QQQA 3EAWX 3KGBA 4KY8A 1TDUA 2AAZA 1TRGA 3JSUA 1ZPRA 3N5EA 3EHIX 1BQ2A 1TJSA 1EVGA 5H38A 3B5BA 4EZ8A 1NJCA 3BHLA 3IJZA 1BO7A 2RDAA 1BDUA 2OIPA 4UP1A 1HZWA 3BZ0A 3KJRA 3DL6A 3EBUA 1EVFA 3V8HA 1BP6A 1KZIA 2RD8A 1LCEA 1TVWA 5WRNA 2TDDA 4GEVA 3IX6A 4KPWA 3QG2A 4LRRA 1JMIA 2TDMA 3IRMA 4FGTA 1AXWA 4GD7A 5HS3A 5J7WA 1JU6A 2FTOX 3EJLA 3UM6A 1TLSA 1HW4A 5H39A 3IK1A 4IQBA 1KCEA 4IQQA 1B49A 1JUTA 1TDBA 3DL5A 2G86A 3BYXA 4XSCA 4JEFA 5H3AA 3TMSA 1TSMA 3CL9A 3B9HA 1NJAA 1LCAA 1AOBA 1B02A 1F4EA 1TLCA 1BKOA 2BBQA 4F2VA 2FTQA 3QGTA 3INVA 1AJMA 4G2OX 1NCEA 4TMSA 4FOAA 4H0UA 3UM8A 1FFLA 3N5EB 1TSDA 2VETA 1TVUA 3QJ7A 3DGAC 1F4FA 1SEJA 3H9KA 4FOGA 3EGYX 2G8DA 4FQSA 4H0RA 4O1XA 5FCTA 1FWMA 1SYNA 1TSWA 1BO8A 1RTSA 1CI7A 1JTUA 1TVVA 4ISWA 4Q0DA 4DQ1A 4EILA 3BNZA 3IHIA 2TSCA 1VZBA 3C06A 4XSEA 1VZAA 1AN5A 1TSYA 1BKPA 1TSVA 3EF9A 4G6WX 1THYA 3IROA 1J3IC 1B5DA 1AIQA 3UWLB 4H1IA 4EB4A 1EV5A 1HVYA 3NRRA 4ECKA 4Q0EA 4KNZA 1TDCA 1YPVA 4XSDA 4O1UA 1JG0A 2ONBA 1EV8A 4IRRA 4DP3A 1HW3A 1J3KC 4EINA 1BSFA 1F4CA 1VZEA 2VF0A 3CLBA 3GH2X 3KJSA 4KYAA 1VZDA 3I3RA 1TYSA 1BQ1A
chains in the Genus database with same CATH superfamily
1F4BA 3ED7A 3HJ3A 1F28A 1JUJA 1TSZA 3N5GA 1KZJA 3BHRA 1TSXA 3GG5A 3BFIA 2RD8B 1NJDA 3DG8C 4E5OA 4ISKA 4O7UA 4GYHA 1TSNA 3C0AA 1NJBA 1BJGA 1BP0A 3IRNA 3HB8A 3GH0A 3K2HA 1JMFA 2H2QA 1JMHA 1I00A 3UM5A 2TSRA 4O1XD 3BGXA 4DPHA 2A9WA 5BY6A 4PSGA 1DDUA 1F4DA 1B5EA 4DPDA 3IK0A 1F4GA 2G89A 2G8XA 1JTQA 4KY4A 1BSPA 3EDWX 1J3JC 4FOXA 4E28A 3UWLA 3OB7A 1TSLA 1VZCA 2FTNA 2G8AA 1BIDA 1BPJA 1JMGA 1TISA 2KCEA 3HBBA 1QZFA 1TDAA 1LCBA 1DNAA 1NJEA 1QQQA 3EAWX 3KGBA 4KY8A 1TDUA 2AAZA 1TRGA 3JSUA 1ZPRA 3N5EA 3EHIX 1BQ2A 1TJSA 1EVGA 5H38A 3B5BA 4EZ8A 1NJCA 3BHLA 3IJZA 1BO7A 2RDAA 1BDUA 2OIPA 4UP1A 1HZWA 3BZ0A 3KJRA 3DL6A 3EBUA 1EVFA 3V8HA 1BP6A 1KZIA 2RD8A 1LCEA 1TVWA 5WRNA 2TDDA 4GEVA 3IX6A 4KPWA 3QG2A 4LRRA 1JMIA 2TDMA 3IRMA 4FGTA 1AXWA 4GD7A 5HS3A 5J7WA 1JU6A 2FTOX 3EJLA 3UM6A 1TLSA 1HW4A 5H39A 3IK1A 4IQBA 1KCEA 4IQQA 1B49A 1JUTA 1TDBA 3DL5A 2G86A 3BYXA 4XSCA 4JEFA 5H3AA 3TMSA 1TSMA 3CL9A 3B9HA 1NJAA 1LCAA 1AOBA 1B02A 1F4EA 1TLCA 1BKOA 2BBQA 4F2VA 2FTQA 3QGTA 3INVA 1AJMA 4G2OX 1NCEA 4TMSA 4FOAA 4H0UA 3UM8A 1FFLA 3N5EB 1TSDA 2VETA 1TVUA 3QJ7A 3DGAC 1F4FA 1SEJA 3H9KA 4FOGA 3EGYX 2G8DA 4FQSA 4H0RA 4O1XA 5FCTA 1FWMA 1SYNA 1TSWA 1BO8A 1RTSA 1CI7A 1JTUA 1TVVA 4ISWA 4Q0DA 4DQ1A 4EILA 3BNZA 3IHIA 2TSCA 1VZBA 3C06A 4XSEA 1VZAA 1AN5A 1TSYA 1BKPA 1TSVA 3EF9A 4G6WX 1THYA 3IROA 1J3IC 1B5DA 1AIQA 3UWLB 4H1IA 4EB4A 1EV5A 1HVYA 3NRRA 4ECKA 4Q0EA 4KNZA 1TDCA 1YPVA 4XSDA 4O1UA 1JG0A 2ONBA 1EV8A 4IRRA 4DP3A 1HW3A 1J3KC 4EINA 1BSFA 1F4CA 1VZEA 2VF0A 3CLBA 3GH2X 3KJSA 4KYAA 1VZDA 3I3RA 1TYSA 1BQ1A
chains in the Genus database with same CATH topology
1F4BA 3ED7A 3HJ3A 1F28A 1JUJA 1TSZA 3N5GA 1KZJA 3BHRA 1TSXA 3GG5A 3BFIA 2RD8B 1NJDA 3DG8C 4E5OA 4ISKA 4O7UA 4GYHA 1TSNA 3C0AA 1NJBA 1BJGA 1BP0A 3IRNA 3HB8A 3GH0A 3K2HA 1JMFA 2H2QA 1JMHA 1I00A 3UM5A 2TSRA 4O1XD 3BGXA 4DPHA 2A9WA 5BY6A 4PSGA 1DDUA 1F4DA 1B5EA 4DPDA 3IK0A 1F4GA 2G89A 2G8XA 1JTQA 4KY4A 1BSPA 3EDWX 1J3JC 4FOXA 4E28A 3UWLA 3OB7A 1TSLA 1VZCA 2FTNA 2G8AA 1BIDA 1BPJA 1JMGA 1TISA 2KCEA 3HBBA 1QZFA 1TDAA 1LCBA 1DNAA 1NJEA 1QQQA 3EAWX 3KGBA 4KY8A 1TDUA 2AAZA 1TRGA 3JSUA 1ZPRA 3N5EA 3EHIX 1BQ2A 1TJSA 1EVGA 5H38A 3B5BA 4EZ8A 1NJCA 3BHLA 3IJZA 1BO7A 2RDAA 1BDUA 2OIPA 4UP1A 1HZWA 3BZ0A 3KJRA 3DL6A 3EBUA 1EVFA 3V8HA 1BP6A 1KZIA 2RD8A 1LCEA 1TVWA 5WRNA 2TDDA 4GEVA 3IX6A 4KPWA 3QG2A 4LRRA 1JMIA 2TDMA 3IRMA 4FGTA 1AXWA 4GD7A 5HS3A 5J7WA 1JU6A 2FTOX 3EJLA 3UM6A 1TLSA 1HW4A 5H39A 3IK1A 4IQBA 1KCEA 4IQQA 1B49A 1JUTA 1TDBA 3DL5A 2G86A 3BYXA 4XSCA 4JEFA 5H3AA 3TMSA 1TSMA 3CL9A 3B9HA 1NJAA 1LCAA 1AOBA 1B02A 1F4EA 1TLCA 1BKOA 2BBQA 4F2VA 2FTQA 3QGTA 3INVA 1AJMA 4G2OX 1NCEA 4TMSA 4FOAA 4H0UA 3UM8A 1FFLA 3N5EB 1TSDA 2VETA 1TVUA 3QJ7A 3DGAC 1F4FA 1SEJA 3H9KA 4FOGA 3EGYX 2G8DA 4FQSA 4H0RA 4O1XA 5FCTA 1FWMA 1SYNA 1TSWA 1BO8A 1RTSA 1CI7A 1JTUA 1TVVA 4ISWA 4Q0DA 4DQ1A 4EILA 3BNZA 3IHIA 2TSCA 1VZBA 3C06A 4XSEA 1VZAA 1AN5A 1TSYA 1BKPA 1TSVA 3EF9A 4G6WX 1THYA 3IROA 1J3IC 1B5DA 1AIQA 3UWLB 4H1IA 4EB4A 1EV5A 1HVYA 3NRRA 4ECKA 4Q0EA 4KNZA 1TDCA 1YPVA 4XSDA 4O1UA 1JG0A 2ONBA 1EV8A 4IRRA 4DP3A 1HW3A 1J3KC 4EINA 1BSFA 1F4CA 1VZEA 2VF0A 3CLBA 3GH2X 3KJSA 4KYAA 1VZDA 3I3RA 1TYSA 1BQ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F4B A;  3ED7 A;  3HJ3 A;  1F28 A;  1JUJ A;  1TSZ A;  3N5G A;  1KZJ A;  3BHR A;  1TSX A;  3GG5 A;  3BFI A;  2RD8 B;  1NJD A;  3DG8 C;  4E5O A;  4ISK A;  4O7U A;  4GYH A;  1TSN A;  3C0A A;  1NJB A;  1BJG A;  1BP0 A;  3IRN A;  3HB8 A;  3GH0 A;  3K2H A;  1JMF A;  2H2Q A;  1JMH A;  1I00 A;  3UM5 A;  2TSR A;  4O1X D;  3BGX A;  4DPH A;  2A9W A;  5BY6 A;  4PSG A;  1DDU A;  1F4D A;  1B5E A;  4DPD A;  3IK0 A;  1F4G A;  2G89 A;  2G8X A;  1JTQ A;  4KY4 A;  1BSP A;  3EDW X;  1J3J C;  4FOX A;  4E28 A;  3UWL A;  3OB7 A;  1TSL A;  1VZC A;  2FTN A;  2G8A A;  1BID A;  1BPJ A;  1JMG A;  1TIS A;  2KCE A;  3HBB A;  1QZF A;  1TDA A;  1LCB A;  1DNA A;  1NJE A;  1QQQ A;  3EAW X;  3KGB A;  4KY8 A;  1TDU A;  2AAZ A;  1TRG A;  3JSU A;  1ZPR A;  3N5E A;  3EHI X;  1BQ2 A;  1TJS A;  1EVG A;  5H38 A;  3B5B A;  4EZ8 A;  1NJC A;  3BHL A;  3IJZ A;  1BO7 A;  2RDA A;  1BDU A;  2OIP A;  4UP1 A;  1HZW A;  3BZ0 A;  3KJR A;  3DL6 A;  3EBU A;  1EVF A;  3V8H A;  1BP6 A;  1KZI A;  2RD8 A;  1LCE A;  1TVW A;  5WRN A;  2TDD A;  4GEV A;  3IX6 A;  4KPW A;  3QG2 A;  4LRR A;  1JMI A;  2TDM A;  3IRM A;  4FGT A;  1AXW A;  4GD7 A;  5HS3 A;  5J7W A;  1JU6 A;  2FTO X;  3EJL A;  3UM6 A;  1TLS A;  1HW4 A;  5H39 A;  3IK1 A;  4IQB A;  1KCE A;  4IQQ A;  1B49 A;  1JUT A;  1TDB A;  3DL5 A;  2G86 A;  3BYX A;  4XSC A;  4JEF A;  5H3A A;  3TMS A;  1TSM A;  3CL9 A;  3B9H A;  1NJA A;  1LCA A;  1AOB A;  1B02 A;  1F4E A;  1TLC A;  1BKO A;  2BBQ A;  4F2V A;  2FTQ A;  3QGT A;  3INV A;  1AJM A;  4G2O X;  1NCE A;  4TMS A;  4FOA A;  4H0U A;  3UM8 A;  1FFL A;  3N5E B;  1TSD A;  2VET A;  1TVU A;  3QJ7 A;  3DGA C;  1F4F A;  1SEJ A;  3H9K A;  4FOG A;  3EGY X;  2G8D A;  4FQS A;  4H0R A;  4O1X A;  5FCT A;  1FWM A;  1SYN A;  1TSW A;  1BO8 A;  1RTS A;  1CI7 A;  1JTU A;  1TVV A;  4ISW A;  4Q0D A;  4DQ1 A;  4EIL A;  3BNZ A;  3IHI A;  2TSC A;  1VZB A;  3C06 A;  4XSE A;  1VZA A;  1AN5 A;  1TSY A;  1BKP A;  1TSV A;  3EF9 A;  4G6W X;  1THY A;  3IRO A;  1J3I C;  1B5D A;  1AIQ A;  3UWL B;  4H1I A;  4EB4 A;  1EV5 A;  1HVY A;  3NRR A;  4ECK A;  4Q0E A;  4KNZ A;  1TDC A;  1YPV A;  4XSD A;  4O1U A;  1JG0 A;  2ONB A;  1EV8 A;  4IRR A;  4DP3 A;  1HW3 A;  1J3K C;  4EIN A;  1BSF A;  1F4C A;  1VZE A;  2VF0 A;  3CLB A;  3GH2 X;  3KJS A;  4KYA A;  1VZD A;  3I3R A;  1TYS A;  1BQ1 A; 
#chains in the Genus database with same CATH topology
 1F4B A;  3ED7 A;  3HJ3 A;  1F28 A;  1JUJ A;  1TSZ A;  3N5G A;  1KZJ A;  3BHR A;  1TSX A;  3GG5 A;  3BFI A;  2RD8 B;  1NJD A;  3DG8 C;  4E5O A;  4ISK A;  4O7U A;  4GYH A;  1TSN A;  3C0A A;  1NJB A;  1BJG A;  1BP0 A;  3IRN A;  3HB8 A;  3GH0 A;  3K2H A;  1JMF A;  2H2Q A;  1JMH A;  1I00 A;  3UM5 A;  2TSR A;  4O1X D;  3BGX A;  4DPH A;  2A9W A;  5BY6 A;  4PSG A;  1DDU A;  1F4D A;  1B5E A;  4DPD A;  3IK0 A;  1F4G A;  2G89 A;  2G8X A;  1JTQ A;  4KY4 A;  1BSP A;  3EDW X;  1J3J C;  4FOX A;  4E28 A;  3UWL A;  3OB7 A;  1TSL A;  1VZC A;  2FTN A;  2G8A A;  1BID A;  1BPJ A;  1JMG A;  1TIS A;  2KCE A;  3HBB A;  1QZF A;  1TDA A;  1LCB A;  1DNA A;  1NJE A;  1QQQ A;  3EAW X;  3KGB A;  4KY8 A;  1TDU A;  2AAZ A;  1TRG A;  3JSU A;  1ZPR A;  3N5E A;  3EHI X;  1BQ2 A;  1TJS A;  1EVG A;  5H38 A;  3B5B A;  4EZ8 A;  1NJC A;  3BHL A;  3IJZ A;  1BO7 A;  2RDA A;  1BDU A;  2OIP A;  4UP1 A;  1HZW A;  3BZ0 A;  3KJR A;  3DL6 A;  3EBU A;  1EVF A;  3V8H A;  1BP6 A;  1KZI A;  2RD8 A;  1LCE A;  1TVW A;  5WRN A;  2TDD A;  4GEV A;  3IX6 A;  4KPW A;  3QG2 A;  4LRR A;  1JMI A;  2TDM A;  3IRM A;  4FGT A;  1AXW A;  4GD7 A;  5HS3 A;  5J7W A;  1JU6 A;  2FTO X;  3EJL A;  3UM6 A;  1TLS A;  1HW4 A;  5H39 A;  3IK1 A;  4IQB A;  1KCE A;  4IQQ A;  1B49 A;  1JUT A;  1TDB A;  3DL5 A;  2G86 A;  3BYX A;  4XSC A;  4JEF A;  5H3A A;  3TMS A;  1TSM A;  3CL9 A;  3B9H A;  1NJA A;  1LCA A;  1AOB A;  1B02 A;  1F4E A;  1TLC A;  1BKO A;  2BBQ A;  4F2V A;  2FTQ A;  3QGT A;  3INV A;  1AJM A;  4G2O X;  1NCE A;  4TMS A;  4FOA A;  4H0U A;  3UM8 A;  1FFL A;  3N5E B;  1TSD A;  2VET A;  1TVU A;  3QJ7 A;  3DGA C;  1F4F A;  1SEJ A;  3H9K A;  4FOG A;  3EGY X;  2G8D A;  4FQS A;  4H0R A;  4O1X A;  5FCT A;  1FWM A;  1SYN A;  1TSW A;  1BO8 A;  1RTS A;  1CI7 A;  1JTU A;  1TVV A;  4ISW A;  4Q0D A;  4DQ1 A;  4EIL A;  3BNZ A;  3IHI A;  2TSC A;  1VZB A;  3C06 A;  4XSE A;  1VZA A;  1AN5 A;  1TSY A;  1BKP A;  1TSV A;  3EF9 A;  4G6W X;  1THY A;  3IRO A;  1J3I C;  1B5D A;  1AIQ A;  3UWL B;  4H1I A;  4EB4 A;  1EV5 A;  1HVY A;  3NRR A;  4ECK A;  4Q0E A;  4KNZ A;  1TDC A;  1YPV A;  4XSD A;  4O1U A;  1JG0 A;  2ONB A;  1EV8 A;  4IRR A;  4DP3 A;  1HW3 A;  1J3K C;  4EIN A;  1BSF A;  1F4C A;  1VZE A;  2VF0 A;  3CLB A;  3GH2 X;  3KJS A;  4KYA A;  1VZD A;  3I3R A;  1TYS A;  1BQ1 A; 
#chains in the Genus database with same CATH homology
 1F4B A;  3ED7 A;  3HJ3 A;  1F28 A;  1JUJ A;  1TSZ A;  3N5G A;  1KZJ A;  3BHR A;  1TSX A;  3GG5 A;  3BFI A;  2RD8 B;  1NJD A;  3DG8 C;  4E5O A;  4ISK A;  4O7U A;  4GYH A;  1TSN A;  3C0A A;  1NJB A;  1BJG A;  1BP0 A;  3IRN A;  3HB8 A;  3GH0 A;  3K2H A;  1JMF A;  2H2Q A;  1JMH A;  1I00 A;  3UM5 A;  2TSR A;  4O1X D;  3BGX A;  4DPH A;  2A9W A;  5BY6 A;  4PSG A;  1DDU A;  1F4D A;  1B5E A;  4DPD A;  3IK0 A;  1F4G A;  2G89 A;  2G8X A;  1JTQ A;  4KY4 A;  1BSP A;  3EDW X;  1J3J C;  4FOX A;  4E28 A;  3UWL A;  3OB7 A;  1TSL A;  1VZC A;  2FTN A;  2G8A A;  1BID A;  1BPJ A;  1JMG A;  1TIS A;  2KCE A;  3HBB A;  1QZF A;  1TDA A;  1LCB A;  1DNA A;  1NJE A;  1QQQ A;  3EAW X;  3KGB A;  4KY8 A;  1TDU A;  2AAZ A;  1TRG A;  3JSU A;  1ZPR A;  3N5E A;  3EHI X;  1BQ2 A;  1TJS A;  1EVG A;  5H38 A;  3B5B A;  4EZ8 A;  1NJC A;  3BHL A;  3IJZ A;  1BO7 A;  2RDA A;  1BDU A;  2OIP A;  4UP1 A;  1HZW A;  3BZ0 A;  3KJR A;  3DL6 A;  3EBU A;  1EVF A;  3V8H A;  1BP6 A;  1KZI A;  2RD8 A;  1LCE A;  1TVW A;  5WRN A;  2TDD A;  4GEV A;  3IX6 A;  4KPW A;  3QG2 A;  4LRR A;  1JMI A;  2TDM A;  3IRM A;  4FGT A;  1AXW A;  4GD7 A;  5HS3 A;  5J7W A;  1JU6 A;  2FTO X;  3EJL A;  3UM6 A;  1TLS A;  1HW4 A;  5H39 A;  3IK1 A;  4IQB A;  1KCE A;  4IQQ A;  1B49 A;  1JUT A;  1TDB A;  3DL5 A;  2G86 A;  3BYX A;  4XSC A;  4JEF A;  5H3A A;  3TMS A;  1TSM A;  3CL9 A;  3B9H A;  1NJA A;  1LCA A;  1AOB A;  1B02 A;  1F4E A;  1TLC A;  1BKO A;  2BBQ A;  4F2V A;  2FTQ A;  3QGT A;  3INV A;  1AJM A;  4G2O X;  1NCE A;  4TMS A;  4FOA A;  4H0U A;  3UM8 A;  1FFL A;  3N5E B;  1TSD A;  2VET A;  1TVU A;  3QJ7 A;  3DGA C;  1F4F A;  1SEJ A;  3H9K A;  4FOG A;  3EGY X;  2G8D A;  4FQS A;  4H0R A;  4O1X A;  5FCT A;  1FWM A;  1SYN A;  1TSW A;  1BO8 A;  1RTS A;  1CI7 A;  1JTU A;  1TVV A;  4ISW A;  4Q0D A;  4DQ1 A;  4EIL A;  3BNZ A;  3IHI A;  2TSC A;  1VZB A;  3C06 A;  4XSE A;  1VZA A;  1AN5 A;  1TSY A;  1BKP A;  1TSV A;  3EF9 A;  4G6W X;  1THY A;  3IRO A;  1J3I C;  1B5D A;  1AIQ A;  3UWL B;  4H1I A;  4EB4 A;  1EV5 A;  1HVY A;  3NRR A;  4ECK A;  4Q0E A;  4KNZ A;  1TDC A;  1YPV A;  4XSD A;  4O1U A;  1JG0 A;  2ONB A;  1EV8 A;  4IRR A;  4DP3 A;  1HW3 A;  1J3K C;  4EIN A;  1BSF A;  1F4C A;  1VZE A;  2VF0 A;  3CLB A;  3GH2 X;  3KJS A;  4KYA A;  1VZD A;  3I3R A;  1TYS A;  1BQ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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