1H6HA

Structure of the px domain from p40phox bound to phosphatidylinositol 3-phosphate
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
143
structure length
143
Chain Sequence
AVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPYDSEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
pubmed doi rcsb
molecule tags Px domain
source organism Homo sapiens
molecule keywords NEUTROPHIL CYTOSOL FACTOR 4
total genus 44
structure length 143
sequence length 143
ec nomenclature
pdb deposition date 2001-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 1h6hA00
4IKBA 2WWEA 4AZ9A 2IWLX 2RAJA 2I4KA 4PZGA 4ON3A 4PQOA 3HPBA 1KQ6A 4HASA 2ETTA 4AKVA 3DYTA 4BGJA 1GD5A 1O7KA 2YPSA 4OXWA 4PQPA 2AR5A 3HPCX 3P0CA 2RAIA 3LUIA 4P2JA 2V14A 2CSKA 1XTEA 2DYBA 2REAA 3FOGA 2RAKA 2CZOA 4IKDA 1OCUA 4P2IA 1OCSA 2REDA 1KMDA 2L73A 1XTNA 4IKBB 3IQ2A 2V6VA 1H6HA
chains in the Genus database with same CATH superfamily
4IKBA 2WWEA 4AZ9A 2IWLX 2RAJA 2I4KA 4PZGA 4ON3A 4PQOA 3HPBA 1KQ6A 4HASA 2ETTA 4AKVA 3DYTA 4BGJA 1GD5A 1O7KA 2YPSA 4OXWA 4PQPA 2AR5A 3HPCX 3P0CA 2RAIA 3LUIA 4P2JA 2V14A 2CSKA 1XTEA 2DYBA 2REAA 3FOGA 2RAKA 2CZOA 4IKDA 1OCUA 4P2IA 1OCSA 2REDA 1KMDA 2L73A 1XTNA 4IKBB 3IQ2A 2V6VA 1H6HA
chains in the Genus database with same CATH topology
4IKBA 2WWEA 4AZ9A 2IWLX 2RAJA 2I4KA 4PZGA 4ON3A 4PQOA 3HPBA 1KQ6A 4HASA 2ETTA 4AKVA 3DYTA 4BGJA 1GD5A 1O7KA 2YPSA 4OXWA 4PQPA 2AR5A 3HPCX 3P0CA 2RAIA 3LUIA 4P2JA 2V14A 2CSKA 1XTEA 2DYBA 2REAA 3FOGA 2RAKA 2CZOA 4IKDA 1OCUA 4P2IA 1OCSA 2REDA 1KMDA 2L73A 1XTNA 4IKBB 3IQ2A 2V6VA 1H6HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKB A;  2WWE A;  4AZ9 A;  2IWL X;  2RAJ A;  2I4K A;  4PZG A;  4ON3 A;  4PQO A;  3HPB A;  1KQ6 A;  4HAS A;  2ETT A;  4AKV A;  3DYT A;  4BGJ A;  1GD5 A;  1O7K A;  2YPS A;  4OXW A;  4PQP A;  2AR5 A;  3HPC X;  3P0C A;  2RAI A;  3LUI A;  4P2J A;  2V14 A;  2CSK A;  1XTE A;  2DYB A;  2REA A;  3FOG A;  2RAK A;  2CZO A;  4IKD A;  1OCU A;  4P2I A;  1OCS A;  2RED A;  1KMD A;  2L73 A;  1XTN A;  4IKB B;  3IQ2 A;  2V6V A;  1H6H A; 
#chains in the Genus database with same CATH topology
 4IKB A;  2WWE A;  4AZ9 A;  2IWL X;  2RAJ A;  2I4K A;  4PZG A;  4ON3 A;  4PQO A;  3HPB A;  1KQ6 A;  4HAS A;  2ETT A;  4AKV A;  3DYT A;  4BGJ A;  1GD5 A;  1O7K A;  2YPS A;  4OXW A;  4PQP A;  2AR5 A;  3HPC X;  3P0C A;  2RAI A;  3LUI A;  4P2J A;  2V14 A;  2CSK A;  1XTE A;  2DYB A;  2REA A;  3FOG A;  2RAK A;  2CZO A;  4IKD A;  1OCU A;  4P2I A;  1OCS A;  2RED A;  1KMD A;  2L73 A;  1XTN A;  4IKB B;  3IQ2 A;  2V6V A;  1H6H A; 
#chains in the Genus database with same CATH homology
 4IKB A;  2WWE A;  4AZ9 A;  2IWL X;  2RAJ A;  2I4K A;  4PZG A;  4ON3 A;  4PQO A;  3HPB A;  1KQ6 A;  4HAS A;  2ETT A;  4AKV A;  3DYT A;  4BGJ A;  1GD5 A;  1O7K A;  2YPS A;  4OXW A;  4PQP A;  2AR5 A;  3HPC X;  3P0C A;  2RAI A;  3LUI A;  4P2J A;  2V14 A;  2CSK A;  1XTE A;  2DYB A;  2REA A;  3FOG A;  2RAK A;  2CZO A;  4IKD A;  1OCU A;  4P2I A;  1OCS A;  2RED A;  1KMD A;  2L73 A;  1XTN A;  4IKB B;  3IQ2 A;  2V6V A;  1H6H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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