1JUJA

Human thymidylate synthase bound to dump and ly231514, a pyrrolo(2,3-d)pyrimidine-based antifolate
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
286
structure length
286
Chain Sequence
HGELQYLGQIQHILRCGVEKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases.
pubmed doi rcsb
molecule keywords THYMIDYLATE SYNTHASE
total genus 83
structure length 286
sequence length 286
chains with identical sequence B, C, D
ec nomenclature ec 2.1.1.45: Thymidylate synthase.
pdb deposition date 2001-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00303 Thymidylat_synt Thymidylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase; Chain A Thymidylate synthase/dCMP hydroxymethylase domain 1jujA00
1ZPRA 1VZBA 3DL6A 2BBQA 3C0AA 2A9WA 1BQ2A 4DPDA 4EB4A 1TDCA 1LCBA 3TMSA 1I00A 3HB8A 1SEJA 3ED7A 3GG5A 4KY8A 1VZEA 3INVA 3IX6A 3JSUA 1F4EA 1KZJA 2FTNA 3BZ0A 3DL5A 1TSWA 3I3RA 1NJAA 4G6WX 3BYXA 4KY4A 5FCTA 1TDUA 1TLSA 2FTQA 3IROA 3EAWX 4O7UA 1F28A 1KCEA 1TSDA 1TVVA 2G8DA 4E28A 2VETA 1BPJA 1B49A 1F4DA 1HZWA 2G89A 3H9KA 1RTSA 1BO7A 3HJ3A 3KJRA 4LRRA 1JMGA 3V8HA 1LCEA 1J3KC 1BSPA 3KGBA 3EHIX 1BDUA 3NRRA 3EGYX 4KYAA 2H2QA 1NCEA 1TSMA 1F4CA 3BGXA 1TVUA 1B02A 2TSCA 1FFLA 3HBBA 3IJZA 3EBUA 1NJEA 3GH0A 4GD7A 1FWMA 3BHLA 4XSEA 3UM8A 1EV5A 1BJGA 4XSCA 2FTOX 1TSYA 4EILA 4H1IA 1NJDA 5BY6A 4ECKA 1TSLA 1TVWA 4EZ8A 1THYA 1JU6A 3IRMA 4PSGA 3UWLB 1BP0A 4JEFA 1AIQA 2TDDA 4FQSA 1JG0A 4O1XD 2G86A 5WRNA 1TSXA 1TDAA 3QG2A 2ONBA 4DQ1A 1BSFA 1EVFA 3IHIA 4O1UA 1BIDA 1KZIA 1VZCA 1EV8A 1VZDA 1AJMA 1F4BA 1JUJA 1JMFA 4KNZA 3EDWX 1BP6A 5H39A 1F4GA 2RD8B 4IQBA 4FOXA 3QJ7A 1BKPA 1F4FA 4UP1A 1NJBA 3QGTA 2TDMA 4ISWA 1LCAA 1QQQA 2OIPA 4EINA 1TSNA 3OB7A 1JTUA 4DP3A 5HS3A 3B9HA 4F2VA 1BQ1A 1B5DA 1TRGA 2G8AA 3EJLA 3N5EB 5H38A 1VZAA 1HVYA 1TDBA 1JTQA 4GEVA 1DNAA 3K2HA 1HW3A 3DGAC 3KJSA 1BKOA 3UWLA 1JMIA 1BO8A 1TJSA 3EF9A 4FOGA 1AOBA 2RDAA 4FOAA 3GH2X 1B5EA 2KCEA 2VF0A 4TMSA 1J3IC 1TSVA 3CLBA 1DDUA 1J3JC 1QZFA 3DG8C 4FGTA 4IRRA 4KPWA 5J7WA 3C06A 1TLCA 1NJCA 1EVGA 3CL9A 1JUTA 1TISA 4IQQA 3BFIA 1SYNA 2RD8A 3IRNA 4Q0EA 4DPHA 1TYSA 3IK0A 1CI7A 3IK1A 4ISKA 2TSRA 4G2OX 1HW4A 3B5BA 3BNZA 4H0RA 4XSDA 2G8XA 1AXWA 4E5OA 5H3AA 4GYHA 3N5GA 1TSZA 1YPVA 2AAZA 3UM6A 1AN5A 1JMHA 3N5EA 4H0UA 4O1XA 4Q0DA 3BHRA 3UM5A
chains in the Genus database with same CATH superfamily
1ZPRA 1VZBA 3DL6A 2BBQA 3C0AA 2A9WA 1BQ2A 4DPDA 4EB4A 1TDCA 1LCBA 3TMSA 1I00A 3HB8A 1SEJA 3ED7A 3GG5A 4KY8A 1VZEA 3INVA 3IX6A 3JSUA 1F4EA 1KZJA 2FTNA 3BZ0A 3DL5A 1TSWA 3I3RA 1NJAA 4G6WX 3BYXA 4KY4A 5FCTA 1TDUA 1TLSA 2FTQA 3IROA 3EAWX 4O7UA 1F28A 1KCEA 1TSDA 1TVVA 2G8DA 4E28A 2VETA 1BPJA 1B49A 1F4DA 1HZWA 2G89A 3H9KA 1RTSA 1BO7A 3HJ3A 3KJRA 4LRRA 1JMGA 3V8HA 1LCEA 1J3KC 1BSPA 3KGBA 3EHIX 1BDUA 3NRRA 3EGYX 4KYAA 2H2QA 1NCEA 1TSMA 1F4CA 3BGXA 1TVUA 1B02A 2TSCA 1FFLA 3HBBA 3IJZA 3EBUA 1NJEA 3GH0A 4GD7A 1FWMA 3BHLA 4XSEA 3UM8A 1EV5A 1BJGA 4XSCA 2FTOX 1TSYA 4EILA 4H1IA 1NJDA 5BY6A 4ECKA 1TSLA 1TVWA 4EZ8A 1THYA 1JU6A 3IRMA 4PSGA 3UWLB 1BP0A 4JEFA 1AIQA 2TDDA 4FQSA 1JG0A 4O1XD 2G86A 5WRNA 1TSXA 1TDAA 3QG2A 2ONBA 4DQ1A 1BSFA 1EVFA 3IHIA 4O1UA 1BIDA 1KZIA 1VZCA 1EV8A 1VZDA 1AJMA 1F4BA 1JUJA 1JMFA 4KNZA 3EDWX 1BP6A 5H39A 1F4GA 2RD8B 4IQBA 4FOXA 3QJ7A 1BKPA 1F4FA 4UP1A 1NJBA 3QGTA 2TDMA 4ISWA 1LCAA 1QQQA 2OIPA 4EINA 1TSNA 3OB7A 1JTUA 4DP3A 5HS3A 3B9HA 4F2VA 1BQ1A 1B5DA 1TRGA 2G8AA 3EJLA 3N5EB 5H38A 1VZAA 1HVYA 1TDBA 1JTQA 4GEVA 1DNAA 3K2HA 1HW3A 3DGAC 3KJSA 1BKOA 3UWLA 1JMIA 1BO8A 1TJSA 3EF9A 4FOGA 1AOBA 2RDAA 4FOAA 3GH2X 1B5EA 2KCEA 2VF0A 4TMSA 1J3IC 1TSVA 3CLBA 1DDUA 1J3JC 1QZFA 3DG8C 4FGTA 4IRRA 4KPWA 5J7WA 3C06A 1TLCA 1NJCA 1EVGA 3CL9A 1JUTA 1TISA 4IQQA 3BFIA 1SYNA 2RD8A 3IRNA 4Q0EA 4DPHA 1TYSA 3IK0A 1CI7A 3IK1A 4ISKA 2TSRA 4G2OX 1HW4A 3B5BA 3BNZA 4H0RA 4XSDA 2G8XA 1AXWA 4E5OA 5H3AA 4GYHA 3N5GA 1TSZA 1YPVA 2AAZA 3UM6A 1AN5A 1JMHA 3N5EA 4H0UA 4O1XA 4Q0DA 3BHRA 3UM5A
chains in the Genus database with same CATH topology
1ZPRA 1VZBA 3DL6A 2BBQA 3C0AA 2A9WA 1BQ2A 4DPDA 4EB4A 1TDCA 1LCBA 3TMSA 1I00A 3HB8A 1SEJA 3ED7A 3GG5A 4KY8A 1VZEA 3INVA 3IX6A 3JSUA 1F4EA 1KZJA 2FTNA 3BZ0A 3DL5A 1TSWA 3I3RA 1NJAA 4G6WX 3BYXA 4KY4A 5FCTA 1TDUA 1TLSA 2FTQA 3IROA 3EAWX 4O7UA 1F28A 1KCEA 1TSDA 1TVVA 2G8DA 4E28A 2VETA 1BPJA 1B49A 1F4DA 1HZWA 2G89A 3H9KA 1RTSA 1BO7A 3HJ3A 3KJRA 4LRRA 1JMGA 3V8HA 1LCEA 1J3KC 1BSPA 3KGBA 3EHIX 1BDUA 3NRRA 3EGYX 4KYAA 2H2QA 1NCEA 1TSMA 1F4CA 3BGXA 1TVUA 1B02A 2TSCA 1FFLA 3HBBA 3IJZA 3EBUA 1NJEA 3GH0A 4GD7A 1FWMA 3BHLA 4XSEA 3UM8A 1EV5A 1BJGA 4XSCA 2FTOX 1TSYA 4EILA 4H1IA 1NJDA 5BY6A 4ECKA 1TSLA 1TVWA 4EZ8A 1THYA 1JU6A 3IRMA 4PSGA 3UWLB 1BP0A 4JEFA 1AIQA 2TDDA 4FQSA 1JG0A 4O1XD 2G86A 5WRNA 1TSXA 1TDAA 3QG2A 2ONBA 4DQ1A 1BSFA 1EVFA 3IHIA 4O1UA 1BIDA 1KZIA 1VZCA 1EV8A 1VZDA 1AJMA 1F4BA 1JUJA 1JMFA 4KNZA 3EDWX 1BP6A 5H39A 1F4GA 2RD8B 4IQBA 4FOXA 3QJ7A 1BKPA 1F4FA 4UP1A 1NJBA 3QGTA 2TDMA 4ISWA 1LCAA 1QQQA 2OIPA 4EINA 1TSNA 3OB7A 1JTUA 4DP3A 5HS3A 3B9HA 4F2VA 1BQ1A 1B5DA 1TRGA 2G8AA 3EJLA 3N5EB 5H38A 1VZAA 1HVYA 1TDBA 1JTQA 4GEVA 1DNAA 3K2HA 1HW3A 3DGAC 3KJSA 1BKOA 3UWLA 1JMIA 1BO8A 1TJSA 3EF9A 4FOGA 1AOBA 2RDAA 4FOAA 3GH2X 1B5EA 2KCEA 2VF0A 4TMSA 1J3IC 1TSVA 3CLBA 1DDUA 1J3JC 1QZFA 3DG8C 4FGTA 4IRRA 4KPWA 5J7WA 3C06A 1TLCA 1NJCA 1EVGA 3CL9A 1JUTA 1TISA 4IQQA 3BFIA 1SYNA 2RD8A 3IRNA 4Q0EA 4DPHA 1TYSA 3IK0A 1CI7A 3IK1A 4ISKA 2TSRA 4G2OX 1HW4A 3B5BA 3BNZA 4H0RA 4XSDA 2G8XA 1AXWA 4E5OA 5H3AA 4GYHA 3N5GA 1TSZA 1YPVA 2AAZA 3UM6A 1AN5A 1JMHA 3N5EA 4H0UA 4O1XA 4Q0DA 3BHRA 3UM5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZPR A;  1VZB A;  3DL6 A;  2BBQ A;  3C0A A;  2A9W A;  1BQ2 A;  4DPD A;  4EB4 A;  1TDC A;  1LCB A;  3TMS A;  1I00 A;  3HB8 A;  1SEJ A;  3ED7 A;  3GG5 A;  4KY8 A;  1VZE A;  3INV A;  3IX6 A;  3JSU A;  1F4E A;  1KZJ A;  2FTN A;  3BZ0 A;  3DL5 A;  1TSW A;  3I3R A;  1NJA A;  4G6W X;  3BYX A;  4KY4 A;  5FCT A;  1TDU A;  1TLS A;  2FTQ A;  3IRO A;  3EAW X;  4O7U A;  1F28 A;  1KCE A;  1TSD A;  1TVV A;  2G8D A;  4E28 A;  2VET A;  1BPJ A;  1B49 A;  1F4D A;  1HZW A;  2G89 A;  3H9K A;  1RTS A;  1BO7 A;  3HJ3 A;  3KJR A;  4LRR A;  1JMG A;  3V8H A;  1LCE A;  1J3K C;  1BSP A;  3KGB A;  3EHI X;  1BDU A;  3NRR A;  3EGY X;  4KYA A;  2H2Q A;  1NCE A;  1TSM A;  1F4C A;  3BGX A;  1TVU A;  1B02 A;  2TSC A;  1FFL A;  3HBB A;  3IJZ A;  3EBU A;  1NJE A;  3GH0 A;  4GD7 A;  1FWM A;  3BHL A;  4XSE A;  3UM8 A;  1EV5 A;  1BJG A;  4XSC A;  2FTO X;  1TSY A;  4EIL A;  4H1I A;  1NJD A;  5BY6 A;  4ECK A;  1TSL A;  1TVW A;  4EZ8 A;  1THY A;  1JU6 A;  3IRM A;  4PSG A;  3UWL B;  1BP0 A;  4JEF A;  1AIQ A;  2TDD A;  4FQS A;  1JG0 A;  4O1X D;  2G86 A;  5WRN A;  1TSX A;  1TDA A;  3QG2 A;  2ONB A;  4DQ1 A;  1BSF A;  1EVF A;  3IHI A;  4O1U A;  1BID A;  1KZI A;  1VZC A;  1EV8 A;  1VZD A;  1AJM A;  1F4B A;  1JUJ A;  1JMF A;  4KNZ A;  3EDW X;  1BP6 A;  5H39 A;  1F4G A;  2RD8 B;  4IQB A;  4FOX A;  3QJ7 A;  1BKP A;  1F4F A;  4UP1 A;  1NJB A;  3QGT A;  2TDM A;  4ISW A;  1LCA A;  1QQQ A;  2OIP A;  4EIN A;  1TSN A;  3OB7 A;  1JTU A;  4DP3 A;  5HS3 A;  3B9H A;  4F2V A;  1BQ1 A;  1B5D A;  1TRG A;  2G8A A;  3EJL A;  3N5E B;  5H38 A;  1VZA A;  1HVY A;  1TDB A;  1JTQ A;  4GEV A;  1DNA A;  3K2H A;  1HW3 A;  3DGA C;  3KJS A;  1BKO A;  3UWL A;  1JMI A;  1BO8 A;  1TJS A;  3EF9 A;  4FOG A;  1AOB A;  2RDA A;  4FOA A;  3GH2 X;  1B5E A;  2KCE A;  2VF0 A;  4TMS A;  1J3I C;  1TSV A;  3CLB A;  1DDU A;  1J3J C;  1QZF A;  3DG8 C;  4FGT A;  4IRR A;  4KPW A;  5J7W A;  3C06 A;  1TLC A;  1NJC A;  1EVG A;  3CL9 A;  1JUT A;  1TIS A;  4IQQ A;  3BFI A;  1SYN A;  2RD8 A;  3IRN A;  4Q0E A;  4DPH A;  1TYS A;  3IK0 A;  1CI7 A;  3IK1 A;  4ISK A;  2TSR A;  4G2O X;  1HW4 A;  3B5B A;  3BNZ A;  4H0R A;  4XSD A;  2G8X A;  1AXW A;  4E5O A;  5H3A A;  4GYH A;  3N5G A;  1TSZ A;  1YPV A;  2AAZ A;  3UM6 A;  1AN5 A;  1JMH A;  3N5E A;  4H0U A;  4O1X A;  4Q0D A;  3BHR A;  3UM5 A; 
#chains in the Genus database with same CATH topology
 1ZPR A;  1VZB A;  3DL6 A;  2BBQ A;  3C0A A;  2A9W A;  1BQ2 A;  4DPD A;  4EB4 A;  1TDC A;  1LCB A;  3TMS A;  1I00 A;  3HB8 A;  1SEJ A;  3ED7 A;  3GG5 A;  4KY8 A;  1VZE A;  3INV A;  3IX6 A;  3JSU A;  1F4E A;  1KZJ A;  2FTN A;  3BZ0 A;  3DL5 A;  1TSW A;  3I3R A;  1NJA A;  4G6W X;  3BYX A;  4KY4 A;  5FCT A;  1TDU A;  1TLS A;  2FTQ A;  3IRO A;  3EAW X;  4O7U A;  1F28 A;  1KCE A;  1TSD A;  1TVV A;  2G8D A;  4E28 A;  2VET A;  1BPJ A;  1B49 A;  1F4D A;  1HZW A;  2G89 A;  3H9K A;  1RTS A;  1BO7 A;  3HJ3 A;  3KJR A;  4LRR A;  1JMG A;  3V8H A;  1LCE A;  1J3K C;  1BSP A;  3KGB A;  3EHI X;  1BDU A;  3NRR A;  3EGY X;  4KYA A;  2H2Q A;  1NCE A;  1TSM A;  1F4C A;  3BGX A;  1TVU A;  1B02 A;  2TSC A;  1FFL A;  3HBB A;  3IJZ A;  3EBU A;  1NJE A;  3GH0 A;  4GD7 A;  1FWM A;  3BHL A;  4XSE A;  3UM8 A;  1EV5 A;  1BJG A;  4XSC A;  2FTO X;  1TSY A;  4EIL A;  4H1I A;  1NJD A;  5BY6 A;  4ECK A;  1TSL A;  1TVW A;  4EZ8 A;  1THY A;  1JU6 A;  3IRM A;  4PSG A;  3UWL B;  1BP0 A;  4JEF A;  1AIQ A;  2TDD A;  4FQS A;  1JG0 A;  4O1X D;  2G86 A;  5WRN A;  1TSX A;  1TDA A;  3QG2 A;  2ONB A;  4DQ1 A;  1BSF A;  1EVF A;  3IHI A;  4O1U A;  1BID A;  1KZI A;  1VZC A;  1EV8 A;  1VZD A;  1AJM A;  1F4B A;  1JUJ A;  1JMF A;  4KNZ A;  3EDW X;  1BP6 A;  5H39 A;  1F4G A;  2RD8 B;  4IQB A;  4FOX A;  3QJ7 A;  1BKP A;  1F4F A;  4UP1 A;  1NJB A;  3QGT A;  2TDM A;  4ISW A;  1LCA A;  1QQQ A;  2OIP A;  4EIN A;  1TSN A;  3OB7 A;  1JTU A;  4DP3 A;  5HS3 A;  3B9H A;  4F2V A;  1BQ1 A;  1B5D A;  1TRG A;  2G8A A;  3EJL A;  3N5E B;  5H38 A;  1VZA A;  1HVY A;  1TDB A;  1JTQ A;  4GEV A;  1DNA A;  3K2H A;  1HW3 A;  3DGA C;  3KJS A;  1BKO A;  3UWL A;  1JMI A;  1BO8 A;  1TJS A;  3EF9 A;  4FOG A;  1AOB A;  2RDA A;  4FOA A;  3GH2 X;  1B5E A;  2KCE A;  2VF0 A;  4TMS A;  1J3I C;  1TSV A;  3CLB A;  1DDU A;  1J3J C;  1QZF A;  3DG8 C;  4FGT A;  4IRR A;  4KPW A;  5J7W A;  3C06 A;  1TLC A;  1NJC A;  1EVG A;  3CL9 A;  1JUT A;  1TIS A;  4IQQ A;  3BFI A;  1SYN A;  2RD8 A;  3IRN A;  4Q0E A;  4DPH A;  1TYS A;  3IK0 A;  1CI7 A;  3IK1 A;  4ISK A;  2TSR A;  4G2O X;  1HW4 A;  3B5B A;  3BNZ A;  4H0R A;  4XSD A;  2G8X A;  1AXW A;  4E5O A;  5H3A A;  4GYH A;  3N5G A;  1TSZ A;  1YPV A;  2AAZ A;  3UM6 A;  1AN5 A;  1JMH A;  3N5E A;  4H0U A;  4O1X A;  4Q0D A;  3BHR A;  3UM5 A; 
#chains in the Genus database with same CATH homology
 1ZPR A;  1VZB A;  3DL6 A;  2BBQ A;  3C0A A;  2A9W A;  1BQ2 A;  4DPD A;  4EB4 A;  1TDC A;  1LCB A;  3TMS A;  1I00 A;  3HB8 A;  1SEJ A;  3ED7 A;  3GG5 A;  4KY8 A;  1VZE A;  3INV A;  3IX6 A;  3JSU A;  1F4E A;  1KZJ A;  2FTN A;  3BZ0 A;  3DL5 A;  1TSW A;  3I3R A;  1NJA A;  4G6W X;  3BYX A;  4KY4 A;  5FCT A;  1TDU A;  1TLS A;  2FTQ A;  3IRO A;  3EAW X;  4O7U A;  1F28 A;  1KCE A;  1TSD A;  1TVV A;  2G8D A;  4E28 A;  2VET A;  1BPJ A;  1B49 A;  1F4D A;  1HZW A;  2G89 A;  3H9K A;  1RTS A;  1BO7 A;  3HJ3 A;  3KJR A;  4LRR A;  1JMG A;  3V8H A;  1LCE A;  1J3K C;  1BSP A;  3KGB A;  3EHI X;  1BDU A;  3NRR A;  3EGY X;  4KYA A;  2H2Q A;  1NCE A;  1TSM A;  1F4C A;  3BGX A;  1TVU A;  1B02 A;  2TSC A;  1FFL A;  3HBB A;  3IJZ A;  3EBU A;  1NJE A;  3GH0 A;  4GD7 A;  1FWM A;  3BHL A;  4XSE A;  3UM8 A;  1EV5 A;  1BJG A;  4XSC A;  2FTO X;  1TSY A;  4EIL A;  4H1I A;  1NJD A;  5BY6 A;  4ECK A;  1TSL A;  1TVW A;  4EZ8 A;  1THY A;  1JU6 A;  3IRM A;  4PSG A;  3UWL B;  1BP0 A;  4JEF A;  1AIQ A;  2TDD A;  4FQS A;  1JG0 A;  4O1X D;  2G86 A;  5WRN A;  1TSX A;  1TDA A;  3QG2 A;  2ONB A;  4DQ1 A;  1BSF A;  1EVF A;  3IHI A;  4O1U A;  1BID A;  1KZI A;  1VZC A;  1EV8 A;  1VZD A;  1AJM A;  1F4B A;  1JUJ A;  1JMF A;  4KNZ A;  3EDW X;  1BP6 A;  5H39 A;  1F4G A;  2RD8 B;  4IQB A;  4FOX A;  3QJ7 A;  1BKP A;  1F4F A;  4UP1 A;  1NJB A;  3QGT A;  2TDM A;  4ISW A;  1LCA A;  1QQQ A;  2OIP A;  4EIN A;  1TSN A;  3OB7 A;  1JTU A;  4DP3 A;  5HS3 A;  3B9H A;  4F2V A;  1BQ1 A;  1B5D A;  1TRG A;  2G8A A;  3EJL A;  3N5E B;  5H38 A;  1VZA A;  1HVY A;  1TDB A;  1JTQ A;  4GEV A;  1DNA A;  3K2H A;  1HW3 A;  3DGA C;  3KJS A;  1BKO A;  3UWL A;  1JMI A;  1BO8 A;  1TJS A;  3EF9 A;  4FOG A;  1AOB A;  2RDA A;  4FOA A;  3GH2 X;  1B5E A;  2KCE A;  2VF0 A;  4TMS A;  1J3I C;  1TSV A;  3CLB A;  1DDU A;  1J3J C;  1QZF A;  3DG8 C;  4FGT A;  4IRR A;  4KPW A;  5J7W A;  3C06 A;  1TLC A;  1NJC A;  1EVG A;  3CL9 A;  1JUT A;  1TIS A;  4IQQ A;  3BFI A;  1SYN A;  2RD8 A;  3IRN A;  4Q0E A;  4DPH A;  1TYS A;  3IK0 A;  1CI7 A;  3IK1 A;  4ISK A;  2TSR A;  4G2O X;  1HW4 A;  3B5B A;  3BNZ A;  4H0R A;  4XSD A;  2G8X A;  1AXW A;  4E5O A;  5H3A A;  4GYH A;  3N5G A;  1TSZ A;  1YPV A;  2AAZ A;  3UM6 A;  1AN5 A;  1JMH A;  3N5E A;  4H0U A;  4O1X A;  4Q0D A;  3BHR A;  3UM5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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