1LM8C

Structure of a hif-1a-pvhl-elonginb-elonginc complex
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
96
structure length
88
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords ELONGIN B
total genus 29
structure length 88
sequence length 96
ec nomenclature
pdb deposition date 2002-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 1lm8C00
3OHUA 3M5BA 3HVEA 2C9WC 1DSXA 3KVTA 2OVRA 3V7DA 4CXTA 5LLIB 5JH5B 4AP2A 1FS2B 1VCBB 3OGLA 4W9LB 5IBKA 3M52A 3HQIA 1LQBB 3ZRFB 2P1OA 2ASSA 3MKSA 3E4UA 3HTMA 3WSOB 2NZ0B 1R2BA 5BXDA 4B9KB 3C6PA 5H7GA 5A15A 1T1DA 4U2MA 5HYWB 3ZNGB 2A79B 1LM8C 2P1QA 1QDWA 2IHCA 3ZTDB 5FTAA 4WQOC 4U77A 2IF5A 2MA9C 4JTDB 4B95B 3C6OA 4AWJB 4CXJA 4BGCA 3C6NA 2OVQA 1FQVB 4W9EB 2P1MA 1HV2A 4JTAB 2NN2A 4U2NA 1BUOA 5BO4C 2JZ3C 3M4TA 4AJYC 2YY9A 4W9HH 2VPKA 4I6JC 2OVPA 1A68A 1R28A 2E31B 1FS1B 1P22B 5H7HA 3GA1A 4W9GB 2Z8HA 4J8ZA 4UYIA 3ZRCB 2R9RB 4CXIA 3I3NA 4N9F5 3L2OA 5BXBA 3DCGB 4W9JB 4UIJA 3OGKA 3B84A 4W9IB 1LDKD 3ZKJB 1S1GA 3LUTB 4JTCB 4W9KB 4APFA 4CRHA 2VKPA 2E32B 4CP3A 2PPIA 2Q81A 5EUPA 1R29A 1CS3A 3BIMA 3ZTCB 5BXHA 1EOEA 4W9FB 2FNJC 4B9KE 3LBZA 3OGMA 3ZUNB 3HVEB 4BKSB 5DADA 5A6RA 1NEXA 1EOFA 4W9HB 4ZOUA 3OHVA 2P1PA 3HU6A 1QDVA 3FKCA 4BKTB 3LNMB 3DRZA 4JGHC 2IZVC 5DAFA 1EXBE 2I2RA 4W9DB 1EODA 2ASTA 2P1NA 4EOZA 5HZGC 4HXIA 4W9CB 3M8VA 1NN7A
chains in the Genus database with same CATH superfamily
3OHUA 3M5BA 3HVEA 2C9WC 1DSXA 3KVTA 2OVRA 3V7DA 4CXTA 5LLIB 5JH5B 4AP2A 1FS2B 1VCBB 3OGLA 4W9LB 5IBKA 3M52A 3HQIA 1LQBB 3ZRFB 4ZGCA 2P1OA 2ASSA 3MKSA 3E4UA 3HTMA 3WSOB 2NZ0B 1R2BA 5BXDA 4B9KB 3C6PA 5H7GA 5A15A 1T1DA 4U2MA 5HYWB 3ZNGB 2A79B 1LM8C 2P1QA 1QDWA 2IHCA 3ZTDB 5FTAA 4WQOC 4U77A 2IF5A 2MA9C 4JTDB 4B95B 3C6OA 4AWJB 4CXJA 4BGCA 3C6NA 4YY8A 2OVQA 1FQVB 4W9EB 2P1MA 1HV2A 4JTAB 2NN2A 4U2NA 1BUOA 5BO4C 2JZ3C 3M4TA 4AJYC 2YY9A 4W9HH 2VPKA 4I6JC 2OVPA 1A68A 1R28A 2E31B 1FS1B 1P22B 5H7HA 3GA1A 4W9GB 2Z8HA 4J8ZA 4UYIA 3ZRCB 2R9RB 4CXIA 3I3NA 4N9F5 3L2OA 5BXBA 3DCGB 3DRXA 4W9JB 4UIJA 3OGKA 3B84A 4W9IB 1LDKD 3ZKJB 1S1GA 3LUTB 4JTCB 4W9KB 4APFA 4CRHA 2VKPA 2E32B 4CP3A 2PPIA 2Q81A 5EUPA 1R29A 1CS3A 3BIMA 3ZTCB 5BXHA 1EOEA 4W9FB 2FNJC 4B9KE 3LBZA 3OGMA 3ZUNB 3HVEB 4BKSB 5DADA 5A6RA 1NEXA 1EOFA 4W9HB 4ZOUA 3OHVA 2P1PA 3HU6A 1QDVA 3FKCA 4BKTB 3LNMB 3DRZA 4JGHC 2IZVC 3DRYA 5DAFA 1EXBE 2I2RA 4W9DB 1EODA 2ASTA 2P1NA 4EOZA 5HZGC 4HXIA 4W9CB 3M8VA 1NN7A
chains in the Genus database with same CATH topology
3OHUA 3M5BA 3HVEA 2C9WC 1DSXA 3KVTA 2OVRA 3V7DA 4CXTA 5LLIB 5JH5B 4AP2A 1FS2B 1VCBB 3OGLA 4W9LB 5IBKA 3M52A 3HQIA 1LQBB 3ZRFB 4ZGCA 2P1OA 2ASSA 3MKSA 3E4UA 3HTMA 3WSOB 2NZ0B 1R2BA 5BXDA 4B9KB 3C6PA 5H7GA 5A15A 1T1DA 4U2MA 5HYWB 3ZNGB 2A79B 1LM8C 2P1QA 1QDWA 2IHCA 3ZTDB 5FTAA 4WQOC 4U77A 2IF5A 2MA9C 4JTDB 4B95B 3C6OA 4AWJB 4CXJA 4BGCA 3C6NA 4YY8A 2OVQA 1FQVB 4W9EB 2P1MA 1HV2A 4JTAB 2NN2A 4U2NA 1BUOA 5BO4C 2JZ3C 3M4TA 4AJYC 2YY9A 4W9HH 2VPKA 4I6JC 2OVPA 1A68A 1R28A 2E31B 1FS1B 1P22B 5H7HA 3GA1A 4W9GB 2Z8HA 4J8ZA 4UYIA 3ZRCB 2R9RB 4CXIA 3I3NA 4N9F5 3L2OA 5BXBA 3DCGB 3DRXA 4W9JB 4UIJA 3OGKA 3B84A 4W9IB 1LDKD 3ZKJB 1S1GA 3LUTB 4JTCB 4W9KB 4APFA 4CRHA 2VKPA 2E32B 4CP3A 2PPIA 2Q81A 5EUPA 1R29A 1CS3A 3BIMA 3ZTCB 5BXHA 1EOEA 4W9FB 2FNJC 4B9KE 3LBZA 3OGMA 3ZUNB 3HVEB 4BKSB 5DADA 5A6RA 1NEXA 1EOFA 4W9HB 4ZOUA 3OHVA 2P1PA 3HU6A 1QDVA 3FKCA 4BKTB 3LNMB 3DRZA 4JGHC 2IZVC 3DRYA 5DAFA 1EXBE 2I2RA 4W9DB 1EODA 2ASTA 2P1NA 4EOZA 5HZGC 4HXIA 4W9CB 3M8VA 1NN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OHU A;  3M5B A;  3HVE A;  2C9W C;  1DSX A;  3KVT A;  2OVR A;  3V7D A;  4CXT A;  5LLI B;  5JH5 B;  4AP2 A;  1FS2 B;  1VCB B;  3OGL A;  4W9L B;  5IBK A;  3M52 A;  3HQI A;  1LQB B;  3ZRF B;  2P1O A;  2ASS A;  3MKS A;  3E4U A;  3HTM A;  3WSO B;  2NZ0 B;  1R2B A;  5BXD A;  4B9K B;  3C6P A;  5H7G A;  5A15 A;  1T1D A;  4U2M A;  5HYW B;  3ZNG B;  2A79 B;  1LM8 C;  2P1Q A;  1QDW A;  2IHC A;  3ZTD B;  5FTA A;  4WQO C;  4U77 A;  2IF5 A;  2MA9 C;  4JTD B;  4B95 B;  3C6O A;  4AWJ B;  4CXJ A;  4BGC A;  3C6N A;  2OVQ A;  1FQV B;  4W9E B;  2P1M A;  1HV2 A;  4JTA B;  2NN2 A;  4U2N A;  1BUO A;  5BO4 C;  2JZ3 C;  3M4T A;  4AJY C;  2YY9 A;  4W9H H;  2VPK A;  4I6J C;  2OVP A;  1A68 A;  1R28 A;  2E31 B;  1FS1 B;  1P22 B;  5H7H A;  3GA1 A;  4W9G B;  2Z8H A;  4J8Z A;  4UYI A;  3ZRC B;  2R9R B;  4CXI A;  3I3N A;  4N9F 5;  3L2O A;  5BXB A;  3DCG B;  4W9J B;  4UIJ A;  3OGK A;  3B84 A;  4W9I B;  1LDK D;  3ZKJ B;  1S1G A;  3LUT B;  4JTC B;  4W9K B;  4APF A;  4CRH A;  2VKP A;  2E32 B;  4CP3 A;  2PPI A;  2Q81 A;  5EUP A;  1R29 A;  1CS3 A;  3BIM A;  3ZTC B;  5BXH A;  1EOE A;  4W9F B;  2FNJ C;  4B9K E;  3LBZ A;  3OGM A;  3ZUN B;  3HVE B;  4BKS B;  5DAD A;  5A6R A;  1NEX A;  1EOF A;  4W9H B;  4ZOU A;  3OHV A;  2P1P A;  3HU6 A;  1QDV A;  3FKC A;  4BKT B;  3LNM B;  3DRZ A;  4JGH C;  2IZV C;  5DAF A;  1EXB E;  2I2R A;  4W9D B;  1EOD A;  2AST A;  2P1N A;  4EOZ A;  5HZG C;  4HXI A;  4W9C B;  3M8V A;  1NN7 A; 
#chains in the Genus database with same CATH topology
 3OHU A;  3M5B A;  3HVE A;  2C9W C;  1DSX A;  3KVT A;  2OVR A;  3V7D A;  4CXT A;  5LLI B;  5JH5 B;  4AP2 A;  1FS2 B;  1VCB B;  3OGL A;  4W9L B;  5IBK A;  3M52 A;  3HQI A;  1LQB B;  3ZRF B;  4ZGC A;  2P1O A;  2ASS A;  3MKS A;  3E4U A;  3HTM A;  3WSO B;  2NZ0 B;  1R2B A;  5BXD A;  4B9K B;  3C6P A;  5H7G A;  5A15 A;  1T1D A;  4U2M A;  5HYW B;  3ZNG B;  2A79 B;  1LM8 C;  2P1Q A;  1QDW A;  2IHC A;  3ZTD B;  5FTA A;  4WQO C;  4U77 A;  2IF5 A;  2MA9 C;  4JTD B;  4B95 B;  3C6O A;  4AWJ B;  4CXJ A;  4BGC A;  3C6N A;  4YY8 A;  2OVQ A;  1FQV B;  4W9E B;  2P1M A;  1HV2 A;  4JTA B;  2NN2 A;  4U2N A;  1BUO A;  5BO4 C;  2JZ3 C;  3M4T A;  4AJY C;  2YY9 A;  4W9H H;  2VPK A;  4I6J C;  2OVP A;  1A68 A;  1R28 A;  2E31 B;  1FS1 B;  1P22 B;  5H7H A;  3GA1 A;  4W9G B;  2Z8H A;  4J8Z A;  4UYI A;  3ZRC B;  2R9R B;  4CXI A;  3I3N A;  4N9F 5;  3L2O A;  5BXB A;  3DCG B;  3DRX A;  4W9J B;  4UIJ A;  3OGK A;  3B84 A;  4W9I B;  1LDK D;  3ZKJ B;  1S1G A;  3LUT B;  4JTC B;  4W9K B;  4APF A;  4CRH A;  2VKP A;  2E32 B;  4CP3 A;  2PPI A;  2Q81 A;  5EUP A;  1R29 A;  1CS3 A;  3BIM A;  3ZTC B;  5BXH A;  1EOE A;  4W9F B;  2FNJ C;  4B9K E;  3LBZ A;  3OGM A;  3ZUN B;  3HVE B;  4BKS B;  5DAD A;  5A6R A;  1NEX A;  1EOF A;  4W9H B;  4ZOU A;  3OHV A;  2P1P A;  3HU6 A;  1QDV A;  3FKC A;  4BKT B;  3LNM B;  3DRZ A;  4JGH C;  2IZV C;  3DRY A;  5DAF A;  1EXB E;  2I2R A;  4W9D B;  1EOD A;  2AST A;  2P1N A;  4EOZ A;  5HZG C;  4HXI A;  4W9C B;  3M8V A;  1NN7 A; 
#chains in the Genus database with same CATH homology
 3OHU A;  3M5B A;  3HVE A;  2C9W C;  1DSX A;  3KVT A;  2OVR A;  3V7D A;  4CXT A;  5LLI B;  5JH5 B;  4AP2 A;  1FS2 B;  1VCB B;  3OGL A;  4W9L B;  5IBK A;  3M52 A;  3HQI A;  1LQB B;  3ZRF B;  4ZGC A;  2P1O A;  2ASS A;  3MKS A;  3E4U A;  3HTM A;  3WSO B;  2NZ0 B;  1R2B A;  5BXD A;  4B9K B;  3C6P A;  5H7G A;  5A15 A;  1T1D A;  4U2M A;  5HYW B;  3ZNG B;  2A79 B;  1LM8 C;  2P1Q A;  1QDW A;  2IHC A;  3ZTD B;  5FTA A;  4WQO C;  4U77 A;  2IF5 A;  2MA9 C;  4JTD B;  4B95 B;  3C6O A;  4AWJ B;  4CXJ A;  4BGC A;  3C6N A;  4YY8 A;  2OVQ A;  1FQV B;  4W9E B;  2P1M A;  1HV2 A;  4JTA B;  2NN2 A;  4U2N A;  1BUO A;  5BO4 C;  2JZ3 C;  3M4T A;  4AJY C;  2YY9 A;  4W9H H;  2VPK A;  4I6J C;  2OVP A;  1A68 A;  1R28 A;  2E31 B;  1FS1 B;  1P22 B;  5H7H A;  3GA1 A;  4W9G B;  2Z8H A;  4J8Z A;  4UYI A;  3ZRC B;  2R9R B;  4CXI A;  3I3N A;  4N9F 5;  3L2O A;  5BXB A;  3DCG B;  3DRX A;  4W9J B;  4UIJ A;  3OGK A;  3B84 A;  4W9I B;  1LDK D;  3ZKJ B;  1S1G A;  3LUT B;  4JTC B;  4W9K B;  4APF A;  4CRH A;  2VKP A;  2E32 B;  4CP3 A;  2PPI A;  2Q81 A;  5EUP A;  1R29 A;  1CS3 A;  3BIM A;  3ZTC B;  5BXH A;  1EOE A;  4W9F B;  2FNJ C;  4B9K E;  3LBZ A;  3OGM A;  3ZUN B;  3HVE B;  4BKS B;  5DAD A;  5A6R A;  1NEX A;  1EOF A;  4W9H B;  4ZOU A;  3OHV A;  2P1P A;  3HU6 A;  1QDV A;  3FKC A;  4BKT B;  3LNM B;  3DRZ A;  4JGH C;  2IZV C;  3DRY A;  5DAF A;  1EXB E;  2I2R A;  4W9D B;  1EOD A;  2AST A;  2P1N A;  4EOZ A;  5HZG C;  4HXI A;  4W9C B;  3M8V A;  1NN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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