1LM8C

Structure of a hif-1a-pvhl-elonginb-elonginc complex
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
96
structure length
88
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords ELONGIN B
total genus 29
structure length 88
sequence length 96
ec nomenclature
pdb deposition date 2002-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 1lm8C00
3ZRCB 1EOEA 1QDWA 3HU6A 4AJYC 2ASTA 2IHCA 4CXJA 3OHVA 4BKTB 1FS2B 5JH5B 3LNMB 4JTAB 5DADA 5IBKA 5DAFA 1R2BA 1LQBB 5LLIB 1A68A 2R9RB 1R29A 4CRHA 2YY9A 4W9FB 2NN2A 4W9EB 5H7GA 4CXTA 3M4TA 3OGKA 4AWJB 1EOFA 4JTDB 4B9KE 2Z8HA 1FQVB 2NZ0B 2VPKA 1DSXA 3E4UA 1NN7A 3V7DA 3L2OA 3DRZA 4WQOC 2PPIA 1QDVA 5H7HA 3C6OA 3ZNGB 3MKSA 1EODA 2I2RA 3ZKJB 1LM8C 2OVRA 3OGLA 4UIJA 2Q81A 4B95B 5FTAA 1HV2A 1T1DA 2FNJC 4W9HH 1P22B 2C9WC 4ZOUA 3C6PA 5BXBA 3WSOB 4CP3A 4BGCA 1CS3A 3OHUA 4N9F5 5HYWB 2VKPA 3ZUNB 3HVEA 4UYIA 3GA1A 2A79B 4W9KB 2ASSA 2OVPA 5BXDA 4U2MA 4W9CB 1NEXA 5BO4C 4W9IB 3ZTCB 5EUPA 3LUTB 3BIMA 2E31B 1BUOA 3FKCA 4CXIA 1LDKD 5BXHA 4HXIA 4U2NA 3OGMA 4W9DB 3ZRFB 4W9HB 3KVTA 1R28A 1EXBE 4JTCB 3M5BA 2P1OA 2E32B 4AP2A 3M52A 1S1GA 5A15A 4APFA 3ZTDB 4EOZA 2P1PA 4BKSB 3HVEB 2P1QA 1VCBB 2IF5A 3HQIA 3B84A 2P1NA 2JZ3C 4U77A 3I3NA 4W9LB 3DCGB 3C6NA 4I6JC 4J8ZA 3LBZA 5A6RA 2IZVC 2P1MA 4W9GB 3HTMA 4W9JB 1FS1B 3M8VA 4JGHC 4B9KB 2MA9C 2OVQA 5HZGC
chains in the Genus database with same CATH superfamily
3ZRCB 1EOEA 1QDWA 3HU6A 3DRXA 4AJYC 2ASTA 2IHCA 4CXJA 3OHVA 4BKTB 1FS2B 5JH5B 3LNMB 4JTAB 5DADA 5IBKA 5DAFA 1R2BA 1LQBB 5LLIB 1A68A 2R9RB 1R29A 4CRHA 2YY9A 4W9FB 2NN2A 4W9EB 5H7GA 4CXTA 3M4TA 3OGKA 4AWJB 1EOFA 4JTDB 4B9KE 2Z8HA 1FQVB 2NZ0B 2VPKA 1DSXA 3E4UA 1NN7A 3V7DA 3L2OA 3DRZA 4WQOC 2PPIA 1QDVA 5H7HA 3C6OA 3ZNGB 3MKSA 1EODA 2I2RA 3ZKJB 1LM8C 2OVRA 3OGLA 4UIJA 2Q81A 4B95B 5FTAA 1HV2A 1T1DA 2FNJC 4W9HH 1P22B 2C9WC 4ZOUA 3C6PA 5BXBA 3WSOB 4CP3A 4BGCA 1CS3A 3OHUA 4N9F5 5HYWB 2VKPA 3ZUNB 3HVEA 4UYIA 3GA1A 2A79B 4W9KB 2ASSA 2OVPA 5BXDA 4U2MA 4W9CB 1NEXA 5BO4C 4W9IB 3ZTCB 5EUPA 3LUTB 3BIMA 2E31B 1BUOA 3FKCA 4ZGCA 4CXIA 3DRYA 1LDKD 5BXHA 4HXIA 4U2NA 3OGMA 4W9DB 3ZRFB 4W9HB 3KVTA 1R28A 1EXBE 4JTCB 3M5BA 2P1OA 2E32B 4AP2A 3M52A 1S1GA 5A15A 4APFA 3ZTDB 4EOZA 2P1PA 4BKSB 3HVEB 2P1QA 1VCBB 2IF5A 3HQIA 3B84A 2P1NA 2JZ3C 4U77A 3I3NA 4W9LB 3DCGB 3C6NA 4I6JC 4J8ZA 3LBZA 5A6RA 2IZVC 2P1MA 4W9GB 3HTMA 4W9JB 1FS1B 3M8VA 4JGHC 4B9KB 4YY8A 2MA9C 2OVQA 5HZGC
chains in the Genus database with same CATH topology
3ZRCB 1EOEA 1QDWA 3HU6A 3DRXA 4AJYC 2ASTA 2IHCA 4CXJA 3OHVA 4BKTB 1FS2B 5JH5B 3LNMB 4JTAB 5DADA 5IBKA 5DAFA 1R2BA 1LQBB 5LLIB 1A68A 2R9RB 1R29A 4CRHA 2YY9A 4W9FB 2NN2A 4W9EB 5H7GA 4CXTA 3M4TA 3OGKA 4AWJB 1EOFA 4JTDB 4B9KE 2Z8HA 1FQVB 2NZ0B 2VPKA 1DSXA 3E4UA 1NN7A 3V7DA 3L2OA 3DRZA 4WQOC 2PPIA 1QDVA 5H7HA 3C6OA 3ZNGB 3MKSA 1EODA 2I2RA 3ZKJB 1LM8C 2OVRA 3OGLA 4UIJA 2Q81A 4B95B 5FTAA 1HV2A 1T1DA 2FNJC 4W9HH 1P22B 2C9WC 4ZOUA 3C6PA 5BXBA 3WSOB 4CP3A 4BGCA 1CS3A 3OHUA 4N9F5 5HYWB 2VKPA 3ZUNB 3HVEA 4UYIA 3GA1A 2A79B 4W9KB 2ASSA 2OVPA 5BXDA 4U2MA 4W9CB 1NEXA 5BO4C 4W9IB 3ZTCB 5EUPA 3LUTB 3BIMA 2E31B 1BUOA 3FKCA 4ZGCA 4CXIA 3DRYA 1LDKD 5BXHA 4HXIA 4U2NA 3OGMA 4W9DB 3ZRFB 4W9HB 3KVTA 1R28A 1EXBE 4JTCB 3M5BA 2P1OA 2E32B 4AP2A 3M52A 1S1GA 5A15A 4APFA 3ZTDB 4EOZA 2P1PA 4BKSB 3HVEB 2P1QA 1VCBB 2IF5A 3HQIA 3B84A 2P1NA 2JZ3C 4U77A 3I3NA 4W9LB 3DCGB 3C6NA 4I6JC 4J8ZA 3LBZA 5A6RA 2IZVC 2P1MA 4W9GB 3HTMA 4W9JB 1FS1B 3M8VA 4JGHC 4B9KB 4YY8A 2MA9C 2OVQA 5HZGC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZRC B;  1EOE A;  1QDW A;  3HU6 A;  4AJY C;  2AST A;  2IHC A;  4CXJ A;  3OHV A;  4BKT B;  1FS2 B;  5JH5 B;  3LNM B;  4JTA B;  5DAD A;  5IBK A;  5DAF A;  1R2B A;  1LQB B;  5LLI B;  1A68 A;  2R9R B;  1R29 A;  4CRH A;  2YY9 A;  4W9F B;  2NN2 A;  4W9E B;  5H7G A;  4CXT A;  3M4T A;  3OGK A;  4AWJ B;  1EOF A;  4JTD B;  4B9K E;  2Z8H A;  1FQV B;  2NZ0 B;  2VPK A;  1DSX A;  3E4U A;  1NN7 A;  3V7D A;  3L2O A;  3DRZ A;  4WQO C;  2PPI A;  1QDV A;  5H7H A;  3C6O A;  3ZNG B;  3MKS A;  1EOD A;  2I2R A;  3ZKJ B;  1LM8 C;  2OVR A;  3OGL A;  4UIJ A;  2Q81 A;  4B95 B;  5FTA A;  1HV2 A;  1T1D A;  2FNJ C;  4W9H H;  1P22 B;  2C9W C;  4ZOU A;  3C6P A;  5BXB A;  3WSO B;  4CP3 A;  4BGC A;  1CS3 A;  3OHU A;  4N9F 5;  5HYW B;  2VKP A;  3ZUN B;  3HVE A;  4UYI A;  3GA1 A;  2A79 B;  4W9K B;  2ASS A;  2OVP A;  5BXD A;  4U2M A;  4W9C B;  1NEX A;  5BO4 C;  4W9I B;  3ZTC B;  5EUP A;  3LUT B;  3BIM A;  2E31 B;  1BUO A;  3FKC A;  4CXI A;  1LDK D;  5BXH A;  4HXI A;  4U2N A;  3OGM A;  4W9D B;  3ZRF B;  4W9H B;  3KVT A;  1R28 A;  1EXB E;  4JTC B;  3M5B A;  2P1O A;  2E32 B;  4AP2 A;  3M52 A;  1S1G A;  5A15 A;  4APF A;  3ZTD B;  4EOZ A;  2P1P A;  4BKS B;  3HVE B;  2P1Q A;  1VCB B;  2IF5 A;  3HQI A;  3B84 A;  2P1N A;  2JZ3 C;  4U77 A;  3I3N A;  4W9L B;  3DCG B;  3C6N A;  4I6J C;  4J8Z A;  3LBZ A;  5A6R A;  2IZV C;  2P1M A;  4W9G B;  3HTM A;  4W9J B;  1FS1 B;  3M8V A;  4JGH C;  4B9K B;  2MA9 C;  2OVQ A;  5HZG C; 
#chains in the Genus database with same CATH topology
 3ZRC B;  1EOE A;  1QDW A;  3HU6 A;  3DRX A;  4AJY C;  2AST A;  2IHC A;  4CXJ A;  3OHV A;  4BKT B;  1FS2 B;  5JH5 B;  3LNM B;  4JTA B;  5DAD A;  5IBK A;  5DAF A;  1R2B A;  1LQB B;  5LLI B;  1A68 A;  2R9R B;  1R29 A;  4CRH A;  2YY9 A;  4W9F B;  2NN2 A;  4W9E B;  5H7G A;  4CXT A;  3M4T A;  3OGK A;  4AWJ B;  1EOF A;  4JTD B;  4B9K E;  2Z8H A;  1FQV B;  2NZ0 B;  2VPK A;  1DSX A;  3E4U A;  1NN7 A;  3V7D A;  3L2O A;  3DRZ A;  4WQO C;  2PPI A;  1QDV A;  5H7H A;  3C6O A;  3ZNG B;  3MKS A;  1EOD A;  2I2R A;  3ZKJ B;  1LM8 C;  2OVR A;  3OGL A;  4UIJ A;  2Q81 A;  4B95 B;  5FTA A;  1HV2 A;  1T1D A;  2FNJ C;  4W9H H;  1P22 B;  2C9W C;  4ZOU A;  3C6P A;  5BXB A;  3WSO B;  4CP3 A;  4BGC A;  1CS3 A;  3OHU A;  4N9F 5;  5HYW B;  2VKP A;  3ZUN B;  3HVE A;  4UYI A;  3GA1 A;  2A79 B;  4W9K B;  2ASS A;  2OVP A;  5BXD A;  4U2M A;  4W9C B;  1NEX A;  5BO4 C;  4W9I B;  3ZTC B;  5EUP A;  3LUT B;  3BIM A;  2E31 B;  1BUO A;  3FKC A;  4ZGC A;  4CXI A;  3DRY A;  1LDK D;  5BXH A;  4HXI A;  4U2N A;  3OGM A;  4W9D B;  3ZRF B;  4W9H B;  3KVT A;  1R28 A;  1EXB E;  4JTC B;  3M5B A;  2P1O A;  2E32 B;  4AP2 A;  3M52 A;  1S1G A;  5A15 A;  4APF A;  3ZTD B;  4EOZ A;  2P1P A;  4BKS B;  3HVE B;  2P1Q A;  1VCB B;  2IF5 A;  3HQI A;  3B84 A;  2P1N A;  2JZ3 C;  4U77 A;  3I3N A;  4W9L B;  3DCG B;  3C6N A;  4I6J C;  4J8Z A;  3LBZ A;  5A6R A;  2IZV C;  2P1M A;  4W9G B;  3HTM A;  4W9J B;  1FS1 B;  3M8V A;  4JGH C;  4B9K B;  4YY8 A;  2MA9 C;  2OVQ A;  5HZG C; 
#chains in the Genus database with same CATH homology
 3ZRC B;  1EOE A;  1QDW A;  3HU6 A;  3DRX A;  4AJY C;  2AST A;  2IHC A;  4CXJ A;  3OHV A;  4BKT B;  1FS2 B;  5JH5 B;  3LNM B;  4JTA B;  5DAD A;  5IBK A;  5DAF A;  1R2B A;  1LQB B;  5LLI B;  1A68 A;  2R9R B;  1R29 A;  4CRH A;  2YY9 A;  4W9F B;  2NN2 A;  4W9E B;  5H7G A;  4CXT A;  3M4T A;  3OGK A;  4AWJ B;  1EOF A;  4JTD B;  4B9K E;  2Z8H A;  1FQV B;  2NZ0 B;  2VPK A;  1DSX A;  3E4U A;  1NN7 A;  3V7D A;  3L2O A;  3DRZ A;  4WQO C;  2PPI A;  1QDV A;  5H7H A;  3C6O A;  3ZNG B;  3MKS A;  1EOD A;  2I2R A;  3ZKJ B;  1LM8 C;  2OVR A;  3OGL A;  4UIJ A;  2Q81 A;  4B95 B;  5FTA A;  1HV2 A;  1T1D A;  2FNJ C;  4W9H H;  1P22 B;  2C9W C;  4ZOU A;  3C6P A;  5BXB A;  3WSO B;  4CP3 A;  4BGC A;  1CS3 A;  3OHU A;  4N9F 5;  5HYW B;  2VKP A;  3ZUN B;  3HVE A;  4UYI A;  3GA1 A;  2A79 B;  4W9K B;  2ASS A;  2OVP A;  5BXD A;  4U2M A;  4W9C B;  1NEX A;  5BO4 C;  4W9I B;  3ZTC B;  5EUP A;  3LUT B;  3BIM A;  2E31 B;  1BUO A;  3FKC A;  4ZGC A;  4CXI A;  3DRY A;  1LDK D;  5BXH A;  4HXI A;  4U2N A;  3OGM A;  4W9D B;  3ZRF B;  4W9H B;  3KVT A;  1R28 A;  1EXB E;  4JTC B;  3M5B A;  2P1O A;  2E32 B;  4AP2 A;  3M52 A;  1S1G A;  5A15 A;  4APF A;  3ZTD B;  4EOZ A;  2P1P A;  4BKS B;  3HVE B;  2P1Q A;  1VCB B;  2IF5 A;  3HQI A;  3B84 A;  2P1N A;  2JZ3 C;  4U77 A;  3I3N A;  4W9L B;  3DCG B;  3C6N A;  4I6J C;  4J8Z A;  3LBZ A;  5A6R A;  2IZV C;  2P1M A;  4W9G B;  3HTM A;  4W9J B;  1FS1 B;  3M8V A;  4JGH C;  4B9K B;  4YY8 A;  2MA9 C;  2OVQ A;  5HZG C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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