1LQBB

Crystal structure of a hydroxylated hif-1 alpha peptide bound to the pvhl/elongin-c/elongin-b complex
Total Genus 26

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
96
structure length
88
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTVIII1 (37-40)S1 (18-22)TI1 (23-26)S2 (28-32)AH2 (40-46)AH3 (67-83)TII1 (83-86)S3 (59-61)AH1 (33-37)Updating...
connected with : NaN
molecule tags Gene regulation
source organism Homo sapiens
publication title Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
pubmed doi rcsb
molecule keywords Elongin B
total genus 26
structure length 88
sequence length 96
ec nomenclature
pdb deposition date 2002-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 1lqbB00
2PPIA 2VKPA 4W9KB 1FS1B 3M8VA 4BKTB 4W9HB 2VPKA 1A68A 2P1OA 3LNMB 2E31B 3LUTB 2ASTA 2P1NA 3V7DA 1FQVB 4CXTA 3HVEA 3HVEB 5H7GA 2MA9C 3OGLA 3KVTA 1LQBB 5BXDA 4AWJB 4J8ZA 1DSXA 1CS3A 4CXJA 3L2OA 3WSOB 4B9KB 3FKCA 4UIJA 3HU6A 2IF5A 5BXHA 1BUOA 4W9LB 4HXIA 4W9HH 4U2NA 5LLIB 3LBZA 1NEXA 5A6RA 5EUPA 5BO4C 4W9JB 2Q81A 3C6PA 3I3NA 3ZTDB 3ZTCB 4U2MA 4W9DB 1LM8C 1EXBE 3C6NA 4APFA 4B95B 1R28A 2P1PA 4ZOUA 2IZVC 2P1MA 3ZRFB 5IBKA 1HV2A 4CRHA 1T1DA 1EOFA 4W9CB 2IHCA 5DAFA 5BXBA 1VCBB 3OHUA 3BIMA 4JTDB 5JH5B 3OGMA 4W9FB 2R9RB 3DCGB 4AJYC 3OHVA 4N9F5 2P1QA 5FTAA 1EOEA 2E32B 3B84A 3C6OA 3ZRCB 5HZGC 1LDKD 4W9EB 1QDVA 2JZ3C 1P22B 1NN7A 3M5BA 4W9IB 2A79B 3ZUNB 4W9GB 4BGCA 1QDWA 4UYIA 3HQIA 4CP3A 4JTCB 4CXIA 2YY9A 3ZNGB 2OVRA 3MKSA 2OVPA 1EODA 3M4TA 1S1GA 3HTMA 4WQOC 3M52A 3OGKA 5DADA 2Z8HA 4AP2A 5H7HA 4U77A 2I2RA 3ZKJB 3E4UA 4B9KE 3DRZA 4JTAB 4JGHC 2NN2A 3GA1A 1FS2B 4EOZA 2ASSA 2C9WC 2FNJC 4BKSB 2OVQA 5A15A 2NZ0B 4I6JC 5HYWB 1R29A 1R2BA
chains in the Genus database with same CATH superfamily
2PPIA 2VKPA 4W9KB 1FS1B 3M8VA 4BKTB 4W9HB 2VPKA 1A68A 2P1OA 3LNMB 2E31B 3LUTB 2ASTA 2P1NA 3V7DA 3DRYA 1FQVB 4CXTA 3HVEA 3HVEB 5H7GA 2MA9C 3OGLA 3KVTA 1LQBB 5BXDA 4AWJB 4J8ZA 1DSXA 1CS3A 4CXJA 3L2OA 3WSOB 4B9KB 3FKCA 4UIJA 3HU6A 2IF5A 3DRXA 5BXHA 1BUOA 4W9LB 4HXIA 4ZGCA 4W9HH 4U2NA 5LLIB 3LBZA 1NEXA 5A6RA 5EUPA 5BO4C 4W9JB 2Q81A 3C6PA 3I3NA 3ZTDB 3ZTCB 4U2MA 4W9DB 1LM8C 1EXBE 3C6NA 4APFA 4B95B 1R28A 2P1PA 4ZOUA 2IZVC 2P1MA 3ZRFB 5IBKA 1HV2A 4CRHA 1T1DA 1EOFA 4W9CB 2IHCA 5DAFA 5BXBA 1VCBB 3OHUA 3BIMA 4JTDB 5JH5B 3OGMA 4W9FB 2R9RB 3DCGB 4AJYC 3OHVA 4N9F5 2P1QA 5FTAA 1EOEA 2E32B 3B84A 3C6OA 3ZRCB 5HZGC 1LDKD 4W9EB 1QDVA 2JZ3C 1P22B 1NN7A 3M5BA 4W9IB 2A79B 3ZUNB 4W9GB 4BGCA 1QDWA 4UYIA 3HQIA 4CP3A 4JTCB 4CXIA 2YY9A 3ZNGB 2OVRA 4YY8A 3MKSA 2OVPA 1EODA 3M4TA 1S1GA 3HTMA 4WQOC 3M52A 3OGKA 5DADA 2Z8HA 4AP2A 5H7HA 4U77A 2I2RA 3ZKJB 3E4UA 4B9KE 3DRZA 4JTAB 4JGHC 2NN2A 3GA1A 1FS2B 4EOZA 2ASSA 2C9WC 2FNJC 4BKSB 2OVQA 5A15A 2NZ0B 4I6JC 5HYWB 1R29A 1R2BA
chains in the Genus database with same CATH topology
2PPIA 2VKPA 4W9KB 1FS1B 3M8VA 4BKTB 4W9HB 2VPKA 1A68A 2P1OA 3LNMB 2E31B 3LUTB 2ASTA 2P1NA 3V7DA 3DRYA 1FQVB 4CXTA 3HVEA 3HVEB 5H7GA 2MA9C 3OGLA 3KVTA 1LQBB 5BXDA 4AWJB 4J8ZA 1DSXA 1CS3A 4CXJA 3L2OA 3WSOB 4B9KB 3FKCA 4UIJA 3HU6A 2IF5A 3DRXA 5BXHA 1BUOA 4W9LB 4HXIA 4ZGCA 4W9HH 4U2NA 5LLIB 3LBZA 1NEXA 5A6RA 5EUPA 5BO4C 4W9JB 2Q81A 3C6PA 3I3NA 3ZTDB 3ZTCB 4U2MA 4W9DB 1LM8C 1EXBE 3C6NA 4APFA 4B95B 1R28A 2P1PA 4ZOUA 2IZVC 2P1MA 3ZRFB 5IBKA 1HV2A 4CRHA 1T1DA 1EOFA 4W9CB 2IHCA 5DAFA 5BXBA 1VCBB 3OHUA 3BIMA 4JTDB 5JH5B 3OGMA 4W9FB 2R9RB 3DCGB 4AJYC 3OHVA 4N9F5 2P1QA 5FTAA 1EOEA 2E32B 3B84A 3C6OA 3ZRCB 5HZGC 1LDKD 4W9EB 1QDVA 2JZ3C 1P22B 1NN7A 3M5BA 4W9IB 2A79B 3ZUNB 4W9GB 4BGCA 1QDWA 4UYIA 3HQIA 4CP3A 4JTCB 4CXIA 2YY9A 3ZNGB 2OVRA 4YY8A 3MKSA 2OVPA 1EODA 3M4TA 1S1GA 3HTMA 4WQOC 3M52A 3OGKA 5DADA 2Z8HA 4AP2A 5H7HA 4U77A 2I2RA 3ZKJB 3E4UA 4B9KE 3DRZA 4JTAB 4JGHC 2NN2A 3GA1A 1FS2B 4EOZA 2ASSA 2C9WC 2FNJC 4BKSB 2OVQA 5A15A 2NZ0B 4I6JC 5HYWB 1R29A 1R2BA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2PPI A;  2VKP A;  4W9K B;  1FS1 B;  3M8V A;  4BKT B;  4W9H B;  2VPK A;  1A68 A;  2P1O A;  3LNM B;  2E31 B;  3LUT B;  2AST A;  2P1N A;  3V7D A;  1FQV B;  4CXT A;  3HVE A;  3HVE B;  5H7G A;  2MA9 C;  3OGL A;  3KVT A;  1LQB B;  5BXD A;  4AWJ B;  4J8Z A;  1DSX A;  1CS3 A;  4CXJ A;  3L2O A;  3WSO B;  4B9K B;  3FKC A;  4UIJ A;  3HU6 A;  2IF5 A;  5BXH A;  1BUO A;  4W9L B;  4HXI A;  4W9H H;  4U2N A;  5LLI B;  3LBZ A;  1NEX A;  5A6R A;  5EUP A;  5BO4 C;  4W9J B;  2Q81 A;  3C6P A;  3I3N A;  3ZTD B;  3ZTC B;  4U2M A;  4W9D B;  1LM8 C;  1EXB E;  3C6N A;  4APF A;  4B95 B;  1R28 A;  2P1P A;  4ZOU A;  2IZV C;  2P1M A;  3ZRF B;  5IBK A;  1HV2 A;  4CRH A;  1T1D A;  1EOF A;  4W9C B;  2IHC A;  5DAF A;  5BXB A;  1VCB B;  3OHU A;  3BIM A;  4JTD B;  5JH5 B;  3OGM A;  4W9F B;  2R9R B;  3DCG B;  4AJY C;  3OHV A;  4N9F 5;  2P1Q A;  5FTA A;  1EOE A;  2E32 B;  3B84 A;  3C6O A;  3ZRC B;  5HZG C;  1LDK D;  4W9E B;  1QDV A;  2JZ3 C;  1P22 B;  1NN7 A;  3M5B A;  4W9I B;  2A79 B;  3ZUN B;  4W9G B;  4BGC A;  1QDW A;  4UYI A;  3HQI A;  4CP3 A;  4JTC B;  4CXI A;  2YY9 A;  3ZNG B;  2OVR A;  3MKS A;  2OVP A;  1EOD A;  3M4T A;  1S1G A;  3HTM A;  4WQO C;  3M52 A;  3OGK A;  5DAD A;  2Z8H A;  4AP2 A;  5H7H A;  4U77 A;  2I2R A;  3ZKJ B;  3E4U A;  4B9K E;  3DRZ A;  4JTA B;  4JGH C;  2NN2 A;  3GA1 A;  1FS2 B;  4EOZ A;  2ASS A;  2C9W C;  2FNJ C;  4BKS B;  2OVQ A;  5A15 A;  2NZ0 B;  4I6J C;  5HYW B;  1R29 A;  1R2B A; 
#chains in the Genus database with same CATH topology
 2PPI A;  2VKP A;  4W9K B;  1FS1 B;  3M8V A;  4BKT B;  4W9H B;  2VPK A;  1A68 A;  2P1O A;  3LNM B;  2E31 B;  3LUT B;  2AST A;  2P1N A;  3V7D A;  3DRY A;  1FQV B;  4CXT A;  3HVE A;  3HVE B;  5H7G A;  2MA9 C;  3OGL A;  3KVT A;  1LQB B;  5BXD A;  4AWJ B;  4J8Z A;  1DSX A;  1CS3 A;  4CXJ A;  3L2O A;  3WSO B;  4B9K B;  3FKC A;  4UIJ A;  3HU6 A;  2IF5 A;  3DRX A;  5BXH A;  1BUO A;  4W9L B;  4HXI A;  4ZGC A;  4W9H H;  4U2N A;  5LLI B;  3LBZ A;  1NEX A;  5A6R A;  5EUP A;  5BO4 C;  4W9J B;  2Q81 A;  3C6P A;  3I3N A;  3ZTD B;  3ZTC B;  4U2M A;  4W9D B;  1LM8 C;  1EXB E;  3C6N A;  4APF A;  4B95 B;  1R28 A;  2P1P A;  4ZOU A;  2IZV C;  2P1M A;  3ZRF B;  5IBK A;  1HV2 A;  4CRH A;  1T1D A;  1EOF A;  4W9C B;  2IHC A;  5DAF A;  5BXB A;  1VCB B;  3OHU A;  3BIM A;  4JTD B;  5JH5 B;  3OGM A;  4W9F B;  2R9R B;  3DCG B;  4AJY C;  3OHV A;  4N9F 5;  2P1Q A;  5FTA A;  1EOE A;  2E32 B;  3B84 A;  3C6O A;  3ZRC B;  5HZG C;  1LDK D;  4W9E B;  1QDV A;  2JZ3 C;  1P22 B;  1NN7 A;  3M5B A;  4W9I B;  2A79 B;  3ZUN B;  4W9G B;  4BGC A;  1QDW A;  4UYI A;  3HQI A;  4CP3 A;  4JTC B;  4CXI A;  2YY9 A;  3ZNG B;  2OVR A;  4YY8 A;  3MKS A;  2OVP A;  1EOD A;  3M4T A;  1S1G A;  3HTM A;  4WQO C;  3M52 A;  3OGK A;  5DAD A;  2Z8H A;  4AP2 A;  5H7H A;  4U77 A;  2I2R A;  3ZKJ B;  3E4U A;  4B9K E;  3DRZ A;  4JTA B;  4JGH C;  2NN2 A;  3GA1 A;  1FS2 B;  4EOZ A;  2ASS A;  2C9W C;  2FNJ C;  4BKS B;  2OVQ A;  5A15 A;  2NZ0 B;  4I6J C;  5HYW B;  1R29 A;  1R2B A; 
#chains in the Genus database with same CATH homology
 2PPI A;  2VKP A;  4W9K B;  1FS1 B;  3M8V A;  4BKT B;  4W9H B;  2VPK A;  1A68 A;  2P1O A;  3LNM B;  2E31 B;  3LUT B;  2AST A;  2P1N A;  3V7D A;  3DRY A;  1FQV B;  4CXT A;  3HVE A;  3HVE B;  5H7G A;  2MA9 C;  3OGL A;  3KVT A;  1LQB B;  5BXD A;  4AWJ B;  4J8Z A;  1DSX A;  1CS3 A;  4CXJ A;  3L2O A;  3WSO B;  4B9K B;  3FKC A;  4UIJ A;  3HU6 A;  2IF5 A;  3DRX A;  5BXH A;  1BUO A;  4W9L B;  4HXI A;  4ZGC A;  4W9H H;  4U2N A;  5LLI B;  3LBZ A;  1NEX A;  5A6R A;  5EUP A;  5BO4 C;  4W9J B;  2Q81 A;  3C6P A;  3I3N A;  3ZTD B;  3ZTC B;  4U2M A;  4W9D B;  1LM8 C;  1EXB E;  3C6N A;  4APF A;  4B95 B;  1R28 A;  2P1P A;  4ZOU A;  2IZV C;  2P1M A;  3ZRF B;  5IBK A;  1HV2 A;  4CRH A;  1T1D A;  1EOF A;  4W9C B;  2IHC A;  5DAF A;  5BXB A;  1VCB B;  3OHU A;  3BIM A;  4JTD B;  5JH5 B;  3OGM A;  4W9F B;  2R9R B;  3DCG B;  4AJY C;  3OHV A;  4N9F 5;  2P1Q A;  5FTA A;  1EOE A;  2E32 B;  3B84 A;  3C6O A;  3ZRC B;  5HZG C;  1LDK D;  4W9E B;  1QDV A;  2JZ3 C;  1P22 B;  1NN7 A;  3M5B A;  4W9I B;  2A79 B;  3ZUN B;  4W9G B;  4BGC A;  1QDW A;  4UYI A;  3HQI A;  4CP3 A;  4JTC B;  4CXI A;  2YY9 A;  3ZNG B;  2OVR A;  4YY8 A;  3MKS A;  2OVP A;  1EOD A;  3M4T A;  1S1G A;  3HTM A;  4WQO C;  3M52 A;  3OGK A;  5DAD A;  2Z8H A;  4AP2 A;  5H7H A;  4U77 A;  2I2R A;  3ZKJ B;  3E4U A;  4B9K E;  3DRZ A;  4JTA B;  4JGH C;  2NN2 A;  3GA1 A;  1FS2 B;  4EOZ A;  2ASS A;  2C9W C;  2FNJ C;  4BKS B;  2OVQ A;  5A15 A;  2NZ0 B;  4I6J C;  5HYW B;  1R29 A;  1R2B A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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