1QB0A

Human cdc25b catalytic domain
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
177
structure length
177
Chain Sequence
DHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN (M-PHASE INDUCER PHOSPHATASE 2 (CDC25B))
total genus 61
structure length 177
sequence length 177
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 1999-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00581 Rhodanese Rhodanese-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.250.10 Alpha Beta 3-Layer(aba) Sandwich Oxidized Rhodanese; domain 1 Rhodanese-like domain 1qb0A00
3IPOA 3P3AA 1TQ1A 3MZZA 4JGTA 1YM9A 2JTSA 3D1PA 1YS0A 1OKGA 2IFVA 2MRMA 3NTDA 3NHVA 1BOHA 1URHA 3G5JA 5HBQA 5LAMA 2EG4A 3NT6A 2MOLA 3I3UA 3UTNX 3TG1B 1C25A 1GMXA 1ORBA 3HIXA 3AAXA 5LAOA 2EG4B 1YT8A 3OLHA 2FSXA 1YMKA 2HHGA 2JTRA 2MOIA 1DP2A 3O3WA 2VSWA 2JTQA 2IFDA 1VEEA 1H4KX 3IPPA 1E0CA 3ILMA 1H4MX 3AAYA 2EG3A 1WV9A 3FLHA 3FOJA 2DCQA 3I2VA 2ORAA 1RHDA 3R2UA 3TG3A 3GK5A 4OCGA 5HBLA 2KL3A 1UARA 1BOIA 1QB0A 2A2KA 4F67A 3OP3A 1YMDA 3F4AA 3NTAA 1T3KA 2WLXA 3FS5A 2K0ZA 1HZMA 2OUCA 2J6PA 3FNJA 3K9RA 1WHBA 2WLRA 4WH7A 1CWTA 5HBOA 2GWFA 3ICRA 3ICTA 1YMLA 3ICSA 3TP9A 1CWSA 1QXNA 1CWRA 4WH9A 5HPAA 5HBPA 3HZUA 3IWHA 1GN0A 3HWIA 1RHSA 2UZQA
chains in the Genus database with same CATH superfamily
3IPOA 3P3AA 1TQ1A 3MZZA 4JGTA 1YM9A 2JTSA 3D1PA 1YS0A 1OKGA 2IFVA 2MRMA 3NTDA 2Q82A 3NHVA 1BOHA 1URHA 3G5JA 5HBQA 5LAMA 2EG4A 3NT6A 2MOLA 3I3UA 3UTNX 3TG1B 1C25A 1GMXA 1ORBA 3HIXA 3AAXA 5LAOA 2EG4B 1YT8A 3OLHA 2FSXA 1YMKA 2HHGA 2JTRA 2MOIA 1DP2A 3O3WA 2VSWA 2JTQA 2IFDA 1VEEA 1H4KX 3IPPA 1E0CA 3ILMA 1H4MX 3AAYA 2EG3A 1WV9A 3FLHA 3FOJA 2DCQA 3I2VA 2ORAA 1RHDA 3R2UA 3TG3A 3GK5A 4OCGA 5HBLA 2KL3A 1UARA 1BOIA 1QB0A 2A2KA 4F67A 3OP3A 1YMDA 3F4AA 3NTAA 1T3KA 2WLXA 3FS5A 2K0ZA 1HZMA 2OUCA 2J6PA 3FNJA 3K9RA 1WHBA 2WLRA 4WH7A 1CWTA 5HBOA 2GWFA 3ICRA 3ICTA 1YMLA 3ICSA 3TP9A 1CWSA 1QXNA 1CWRA 4WH9A 5HPAA 5HBPA 3HZUA 3IWHA 1GN0A 3HWIA 1RHSA 2UZQA
chains in the Genus database with same CATH topology
3IPOA 3P3AA 1TQ1A 3MZZA 4JGTA 1YM9A 2JTSA 3D1PA 1YS0A 1OKGA 2IFVA 2MRMA 3NTDA 3NHVA 1BOHA 1URHA 3G5JA 5HBQA 5LAMA 2EG4A 3NT6A 2MOLA 3I3UA 3UTNX 3TG1B 1C25A 1GMXA 1ORBA 3HIXA 3AAXA 5LAOA 2EG4B 1YT8A 3OLHA 2FSXA 1YMKA 2HHGA 2JTRA 2MOIA 1DP2A 3O3WA 2VSWA 2JTQA 2IFDA 1VEEA 1H4KX 3IPPA 1E0CA 3ILMA 1H4MX 3AAYA 2EG3A 1WV9A 3FLHA 3FOJA 2DCQA 3I2VA 2ORAA 1RHDA 3R2UA 3TG3A 3GK5A 4OCGA 5HBLA 2KL3A 1UARA 1BOIA 1QB0A 2A2KA 4F67A 3OP3A 1YMDA 3F4AA 3NTAA 1T3KA 2WLXA 3FS5A 2K0ZA 1HZMA 2OUCA 2J6PA 3FNJA 3K9RA 1WHBA 2WLRA 4WH7A 1CWTA 5HBOA 2GWFA 3ICRA 3ICTA 1YMLA 3ICSA 3TP9A 1CWSA 1QXNA 1CWRA 4WH9A 5HPAA 5HBPA 3HZUA 3IWHA 1GN0A 3HWIA 1RHSA 2UZQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IPO A;  3P3A A;  1TQ1 A;  3MZZ A;  4JGT A;  1YM9 A;  2JTS A;  3D1P A;  1YS0 A;  1OKG A;  2IFV A;  2MRM A;  3NTD A;  3NHV A;  1BOH A;  1URH A;  3G5J A;  5HBQ A;  5LAM A;  2EG4 A;  3NT6 A;  2MOL A;  3I3U A;  3UTN X;  3TG1 B;  1C25 A;  1GMX A;  1ORB A;  3HIX A;  3AAX A;  5LAO A;  2EG4 B;  1YT8 A;  3OLH A;  2FSX A;  1YMK A;  2HHG A;  2JTR A;  2MOI A;  1DP2 A;  3O3W A;  2VSW A;  2JTQ A;  2IFD A;  1VEE A;  1H4K X;  3IPP A;  1E0C A;  3ILM A;  1H4M X;  3AAY A;  2EG3 A;  1WV9 A;  3FLH A;  3FOJ A;  2DCQ A;  3I2V A;  2ORA A;  1RHD A;  3R2U A;  3TG3 A;  3GK5 A;  4OCG A;  5HBL A;  2KL3 A;  1UAR A;  1BOI A;  1QB0 A;  2A2K A;  4F67 A;  3OP3 A;  1YMD A;  3F4A A;  3NTA A;  1T3K A;  2WLX A;  3FS5 A;  2K0Z A;  1HZM A;  2OUC A;  2J6P A;  3FNJ A;  3K9R A;  1WHB A;  2WLR A;  4WH7 A;  1CWT A;  5HBO A;  2GWF A;  3ICR A;  3ICT A;  1YML A;  3ICS A;  3TP9 A;  1CWS A;  1QXN A;  1CWR A;  4WH9 A;  5HPA A;  5HBP A;  3HZU A;  3IWH A;  1GN0 A;  3HWI A;  1RHS A;  2UZQ A; 
#chains in the Genus database with same CATH topology
 3IPO A;  3P3A A;  1TQ1 A;  3MZZ A;  4JGT A;  1YM9 A;  2JTS A;  3D1P A;  1YS0 A;  1OKG A;  2IFV A;  2MRM A;  3NTD A;  2Q82 A;  3NHV A;  1BOH A;  1URH A;  3G5J A;  5HBQ A;  5LAM A;  2EG4 A;  3NT6 A;  2MOL A;  3I3U A;  3UTN X;  3TG1 B;  1C25 A;  1GMX A;  1ORB A;  3HIX A;  3AAX A;  5LAO A;  2EG4 B;  1YT8 A;  3OLH A;  2FSX A;  1YMK A;  2HHG A;  2JTR A;  2MOI A;  1DP2 A;  3O3W A;  2VSW A;  2JTQ A;  2IFD A;  1VEE A;  1H4K X;  3IPP A;  1E0C A;  3ILM A;  1H4M X;  3AAY A;  2EG3 A;  1WV9 A;  3FLH A;  3FOJ A;  2DCQ A;  3I2V A;  2ORA A;  1RHD A;  3R2U A;  3TG3 A;  3GK5 A;  4OCG A;  5HBL A;  2KL3 A;  1UAR A;  1BOI A;  1QB0 A;  2A2K A;  4F67 A;  3OP3 A;  1YMD A;  3F4A A;  3NTA A;  1T3K A;  2WLX A;  3FS5 A;  2K0Z A;  1HZM A;  2OUC A;  2J6P A;  3FNJ A;  3K9R A;  1WHB A;  2WLR A;  4WH7 A;  1CWT A;  5HBO A;  2GWF A;  3ICR A;  3ICT A;  1YML A;  3ICS A;  3TP9 A;  1CWS A;  1QXN A;  1CWR A;  4WH9 A;  5HPA A;  5HBP A;  3HZU A;  3IWH A;  1GN0 A;  3HWI A;  1RHS A;  2UZQ A; 
#chains in the Genus database with same CATH homology
 3IPO A;  3P3A A;  1TQ1 A;  3MZZ A;  4JGT A;  1YM9 A;  2JTS A;  3D1P A;  1YS0 A;  1OKG A;  2IFV A;  2MRM A;  3NTD A;  3NHV A;  1BOH A;  1URH A;  3G5J A;  5HBQ A;  5LAM A;  2EG4 A;  3NT6 A;  2MOL A;  3I3U A;  3UTN X;  3TG1 B;  1C25 A;  1GMX A;  1ORB A;  3HIX A;  3AAX A;  5LAO A;  2EG4 B;  1YT8 A;  3OLH A;  2FSX A;  1YMK A;  2HHG A;  2JTR A;  2MOI A;  1DP2 A;  3O3W A;  2VSW A;  2JTQ A;  2IFD A;  1VEE A;  1H4K X;  3IPP A;  1E0C A;  3ILM A;  1H4M X;  3AAY A;  2EG3 A;  1WV9 A;  3FLH A;  3FOJ A;  2DCQ A;  3I2V A;  2ORA A;  1RHD A;  3R2U A;  3TG3 A;  3GK5 A;  4OCG A;  5HBL A;  2KL3 A;  1UAR A;  1BOI A;  1QB0 A;  2A2K A;  4F67 A;  3OP3 A;  1YMD A;  3F4A A;  3NTA A;  1T3K A;  2WLX A;  3FS5 A;  2K0Z A;  1HZM A;  2OUC A;  2J6P A;  3FNJ A;  3K9R A;  1WHB A;  2WLR A;  4WH7 A;  1CWT A;  5HBO A;  2GWF A;  3ICR A;  3ICT A;  1YML A;  3ICS A;  3TP9 A;  1CWS A;  1QXN A;  1CWR A;  4WH9 A;  5HPA A;  5HBP A;  3HZU A;  3IWH A;  1GN0 A;  3HWI A;  1RHS A;  2UZQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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