1XTEA

Crystal structure of cisk-px domain
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
116
structure length
116
Chain Sequence
KESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPRHQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Serine/threonine-protein kinase Sgk3
total genus 27
structure length 116
sequence length 116
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2004-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 1xteA00
1XTNA 4OXWA 4PQOA 4AZ9A 4HASA 1KMDA 3FOGA 3P0CA 4IKDA 4P2IA 4P2JA 2CZOA 2AR5A 2ETTA 2REAA 3LUIA 4AKVA 2CSKA 1XTEA 2I4KA 4IKBB 3DYTA 1GD5A 2YPSA 1OCUA 4ON3A 3HPCX 2L73A 2WWEA 1OCSA 2V6VA 4BGJA 4PZGA 2RAIA 2DYBA 2REDA 3HPBA 3IQ2A 1O7KA 4PQPA 4IKBA 1H6HA 2RAKA 2IWLX 1KQ6A 2RAJA 2V14A
chains in the Genus database with same CATH superfamily
1XTNA 4OXWA 4PQOA 4AZ9A 4HASA 1KMDA 3FOGA 3P0CA 4IKDA 4P2IA 4P2JA 2CZOA 2AR5A 2ETTA 2REAA 3LUIA 4AKVA 2CSKA 1XTEA 2I4KA 4IKBB 3DYTA 1GD5A 2YPSA 1OCUA 4ON3A 3HPCX 2L73A 2WWEA 1OCSA 2V6VA 4BGJA 4PZGA 2RAIA 2DYBA 2REDA 3HPBA 3IQ2A 1O7KA 4PQPA 4IKBA 1H6HA 2RAKA 2IWLX 1KQ6A 2RAJA 2V14A
chains in the Genus database with same CATH topology
1XTNA 4OXWA 4PQOA 4AZ9A 4HASA 1KMDA 3FOGA 3P0CA 4IKDA 4P2IA 4P2JA 2CZOA 2AR5A 2ETTA 2REAA 3LUIA 4AKVA 2CSKA 1XTEA 2I4KA 4IKBB 3DYTA 1GD5A 2YPSA 1OCUA 4ON3A 3HPCX 2L73A 2WWEA 1OCSA 2V6VA 4BGJA 4PZGA 2RAIA 2DYBA 2REDA 3HPBA 3IQ2A 1O7KA 4PQPA 4IKBA 1H6HA 2RAKA 2IWLX 1KQ6A 2RAJA 2V14A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XTN A;  4OXW A;  4PQO A;  4AZ9 A;  4HAS A;  1KMD A;  3FOG A;  3P0C A;  4IKD A;  4P2I A;  4P2J A;  2CZO A;  2AR5 A;  2ETT A;  2REA A;  3LUI A;  4AKV A;  2CSK A;  1XTE A;  2I4K A;  4IKB B;  3DYT A;  1GD5 A;  2YPS A;  1OCU A;  4ON3 A;  3HPC X;  2L73 A;  2WWE A;  1OCS A;  2V6V A;  4BGJ A;  4PZG A;  2RAI A;  2DYB A;  2RED A;  3HPB A;  3IQ2 A;  1O7K A;  4PQP A;  4IKB A;  1H6H A;  2RAK A;  2IWL X;  1KQ6 A;  2RAJ A;  2V14 A; 
#chains in the Genus database with same CATH topology
 1XTN A;  4OXW A;  4PQO A;  4AZ9 A;  4HAS A;  1KMD A;  3FOG A;  3P0C A;  4IKD A;  4P2I A;  4P2J A;  2CZO A;  2AR5 A;  2ETT A;  2REA A;  3LUI A;  4AKV A;  2CSK A;  1XTE A;  2I4K A;  4IKB B;  3DYT A;  1GD5 A;  2YPS A;  1OCU A;  4ON3 A;  3HPC X;  2L73 A;  2WWE A;  1OCS A;  2V6V A;  4BGJ A;  4PZG A;  2RAI A;  2DYB A;  2RED A;  3HPB A;  3IQ2 A;  1O7K A;  4PQP A;  4IKB A;  1H6H A;  2RAK A;  2IWL X;  1KQ6 A;  2RAJ A;  2V14 A; 
#chains in the Genus database with same CATH homology
 1XTN A;  4OXW A;  4PQO A;  4AZ9 A;  4HAS A;  1KMD A;  3FOG A;  3P0C A;  4IKD A;  4P2I A;  4P2J A;  2CZO A;  2AR5 A;  2ETT A;  2REA A;  3LUI A;  4AKV A;  2CSK A;  1XTE A;  2I4K A;  4IKB B;  3DYT A;  1GD5 A;  2YPS A;  1OCU A;  4ON3 A;  3HPC X;  2L73 A;  2WWE A;  1OCS A;  2V6V A;  4BGJ A;  4PZG A;  2RAI A;  2DYB A;  2RED A;  3HPB A;  3IQ2 A;  1O7K A;  4PQP A;  4IKB A;  1H6H A;  2RAK A;  2IWL X;  1KQ6 A;  2RAJ A;  2V14 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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