1XTNA

Crystal structure of cisk-px domain with sulfates
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
111
structure length
111
Chain Sequence
ESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Serine/threonine-protein kinase Sgk3
total genus 30
structure length 111
sequence length 111
chains with identical sequence B
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2004-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 1xtnA00
2REAA 2WWEA 2V6VA 1KMDA 4AZ9A 4P2JA 2L73A 4IKDA 4P2IA 1OCUA 1O7KA 4PZGA 2CSKA 3DYTA 1OCSA 4HASA 4OXWA 2I4KA 3HPCX 3FOGA 4IKBB 1KQ6A 4BGJA 2RAIA 2REDA 2ETTA 4ON3A 4AKVA 2V14A 4IKBA 4PQOA 1H6HA 3LUIA 2AR5A 1GD5A 2CZOA 2IWLX 3P0CA 2RAKA 4PQPA 2YPSA 3IQ2A 3HPBA 1XTEA 2DYBA 1XTNA 2RAJA
chains in the Genus database with same CATH superfamily
2REAA 2WWEA 2V6VA 1KMDA 4AZ9A 4P2JA 2L73A 4IKDA 4P2IA 1OCUA 1O7KA 4PZGA 2CSKA 3DYTA 1OCSA 4HASA 4OXWA 2I4KA 3HPCX 3FOGA 4IKBB 1KQ6A 4BGJA 2RAIA 2REDA 2ETTA 4ON3A 4AKVA 2V14A 4IKBA 4PQOA 1H6HA 3LUIA 2AR5A 1GD5A 2CZOA 2IWLX 3P0CA 2RAKA 4PQPA 2YPSA 3IQ2A 3HPBA 1XTEA 2DYBA 1XTNA 2RAJA
chains in the Genus database with same CATH topology
2REAA 2WWEA 2V6VA 1KMDA 4AZ9A 4P2JA 2L73A 4IKDA 4P2IA 1OCUA 1O7KA 4PZGA 2CSKA 3DYTA 1OCSA 4HASA 4OXWA 2I4KA 3HPCX 3FOGA 4IKBB 1KQ6A 4BGJA 2RAIA 2REDA 2ETTA 4ON3A 4AKVA 2V14A 4IKBA 4PQOA 1H6HA 3LUIA 2AR5A 1GD5A 2CZOA 2IWLX 3P0CA 2RAKA 4PQPA 2YPSA 3IQ2A 3HPBA 1XTEA 2DYBA 1XTNA 2RAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2REA A;  2WWE A;  2V6V A;  1KMD A;  4AZ9 A;  4P2J A;  2L73 A;  4IKD A;  4P2I A;  1OCU A;  1O7K A;  4PZG A;  2CSK A;  3DYT A;  1OCS A;  4HAS A;  4OXW A;  2I4K A;  3HPC X;  3FOG A;  4IKB B;  1KQ6 A;  4BGJ A;  2RAI A;  2RED A;  2ETT A;  4ON3 A;  4AKV A;  2V14 A;  4IKB A;  4PQO A;  1H6H A;  3LUI A;  2AR5 A;  1GD5 A;  2CZO A;  2IWL X;  3P0C A;  2RAK A;  4PQP A;  2YPS A;  3IQ2 A;  3HPB A;  1XTE A;  2DYB A;  1XTN A;  2RAJ A; 
#chains in the Genus database with same CATH topology
 2REA A;  2WWE A;  2V6V A;  1KMD A;  4AZ9 A;  4P2J A;  2L73 A;  4IKD A;  4P2I A;  1OCU A;  1O7K A;  4PZG A;  2CSK A;  3DYT A;  1OCS A;  4HAS A;  4OXW A;  2I4K A;  3HPC X;  3FOG A;  4IKB B;  1KQ6 A;  4BGJ A;  2RAI A;  2RED A;  2ETT A;  4ON3 A;  4AKV A;  2V14 A;  4IKB A;  4PQO A;  1H6H A;  3LUI A;  2AR5 A;  1GD5 A;  2CZO A;  2IWL X;  3P0C A;  2RAK A;  4PQP A;  2YPS A;  3IQ2 A;  3HPB A;  1XTE A;  2DYB A;  1XTN A;  2RAJ A; 
#chains in the Genus database with same CATH homology
 2REA A;  2WWE A;  2V6V A;  1KMD A;  4AZ9 A;  4P2J A;  2L73 A;  4IKD A;  4P2I A;  1OCU A;  1O7K A;  4PZG A;  2CSK A;  3DYT A;  1OCS A;  4HAS A;  4OXW A;  2I4K A;  3HPC X;  3FOG A;  4IKB B;  1KQ6 A;  4BGJ A;  2RAI A;  2RED A;  2ETT A;  4ON3 A;  4AKV A;  2V14 A;  4IKB A;  4PQO A;  1H6H A;  3LUI A;  2AR5 A;  1GD5 A;  2CZO A;  2IWL X;  3P0C A;  2RAK A;  4PQP A;  2YPS A;  3IQ2 A;  3HPB A;  1XTE A;  2DYB A;  1XTN A;  2RAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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