1XTNA

Crystal structure of cisk-px domain with sulfates
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
111
structure length
111
Chain Sequence
ESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Serine/threonine-protein kinase Sgk3
total genus 30
structure length 111
sequence length 111
chains with identical sequence B
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2004-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 1xtnA00
2AR5A 3IQ2A 1H6HA 1XTNA 1O7KA 3LUIA 3HPCX 4IKBB 4PQOA 1KQ6A 2WWEA 4IKDA 4AKVA 2I4KA 4PZGA 4HASA 2RAKA 1GD5A 3FOGA 2DYBA 2IWLX 1OCUA 2YPSA 2RAIA 2RAJA 4OXWA 4P2IA 4P2JA 2L73A 2CZOA 3P0CA 4IKBA 4ON3A 2V6VA 1XTEA 3DYTA 2REAA 2V14A 2ETTA 2CSKA 4PQPA 4BGJA 1OCSA 2REDA 1KMDA 4AZ9A 3HPBA
chains in the Genus database with same CATH superfamily
2AR5A 3IQ2A 1H6HA 1XTNA 1O7KA 3LUIA 3HPCX 4IKBB 4PQOA 1KQ6A 2WWEA 4IKDA 4AKVA 2I4KA 4PZGA 4HASA 2RAKA 1GD5A 3FOGA 2DYBA 2IWLX 1OCUA 2YPSA 2RAIA 2RAJA 4OXWA 4P2IA 4P2JA 2L73A 2CZOA 3P0CA 4IKBA 4ON3A 2V6VA 1XTEA 3DYTA 2REAA 2V14A 2ETTA 2CSKA 4PQPA 4BGJA 1OCSA 2REDA 1KMDA 4AZ9A 3HPBA
chains in the Genus database with same CATH topology
2AR5A 3IQ2A 1H6HA 1XTNA 1O7KA 3LUIA 3HPCX 4IKBB 4PQOA 1KQ6A 2WWEA 4IKDA 4AKVA 2I4KA 4PZGA 4HASA 2RAKA 1GD5A 3FOGA 2DYBA 2IWLX 1OCUA 2YPSA 2RAIA 2RAJA 4OXWA 4P2IA 4P2JA 2L73A 2CZOA 3P0CA 4IKBA 4ON3A 2V6VA 1XTEA 3DYTA 2REAA 2V14A 2ETTA 2CSKA 4PQPA 4BGJA 1OCSA 2REDA 1KMDA 4AZ9A 3HPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AR5 A;  3IQ2 A;  1H6H A;  1XTN A;  1O7K A;  3LUI A;  3HPC X;  4IKB B;  4PQO A;  1KQ6 A;  2WWE A;  4IKD A;  4AKV A;  2I4K A;  4PZG A;  4HAS A;  2RAK A;  1GD5 A;  3FOG A;  2DYB A;  2IWL X;  1OCU A;  2YPS A;  2RAI A;  2RAJ A;  4OXW A;  4P2I A;  4P2J A;  2L73 A;  2CZO A;  3P0C A;  4IKB A;  4ON3 A;  2V6V A;  1XTE A;  3DYT A;  2REA A;  2V14 A;  2ETT A;  2CSK A;  4PQP A;  4BGJ A;  1OCS A;  2RED A;  1KMD A;  4AZ9 A;  3HPB A; 
#chains in the Genus database with same CATH topology
 2AR5 A;  3IQ2 A;  1H6H A;  1XTN A;  1O7K A;  3LUI A;  3HPC X;  4IKB B;  4PQO A;  1KQ6 A;  2WWE A;  4IKD A;  4AKV A;  2I4K A;  4PZG A;  4HAS A;  2RAK A;  1GD5 A;  3FOG A;  2DYB A;  2IWL X;  1OCU A;  2YPS A;  2RAI A;  2RAJ A;  4OXW A;  4P2I A;  4P2J A;  2L73 A;  2CZO A;  3P0C A;  4IKB A;  4ON3 A;  2V6V A;  1XTE A;  3DYT A;  2REA A;  2V14 A;  2ETT A;  2CSK A;  4PQP A;  4BGJ A;  1OCS A;  2RED A;  1KMD A;  4AZ9 A;  3HPB A; 
#chains in the Genus database with same CATH homology
 2AR5 A;  3IQ2 A;  1H6H A;  1XTN A;  1O7K A;  3LUI A;  3HPC X;  4IKB B;  4PQO A;  1KQ6 A;  2WWE A;  4IKD A;  4AKV A;  2I4K A;  4PZG A;  4HAS A;  2RAK A;  1GD5 A;  3FOG A;  2DYB A;  2IWL X;  1OCU A;  2YPS A;  2RAI A;  2RAJ A;  4OXW A;  4P2I A;  4P2J A;  2L73 A;  2CZO A;  3P0C A;  4IKB A;  4ON3 A;  2V6V A;  1XTE A;  3DYT A;  2REA A;  2V14 A;  2ETT A;  2CSK A;  4PQP A;  4BGJ A;  1OCS A;  2RED A;  1KMD A;  4AZ9 A;  3HPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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