2AR5 | Genus

Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	27
sequence length	117
structure length	117
Chain Sequence	MDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVAAKRKIELNSYLQSLMNASTDVAECDLVCTFFHGSHH

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Homo sapiens
publication title	Ligand-binding specificity of PI3Kinase C2alpha PX domain. rcsb
molecule keywords	Phosphoinositide 3-kinase
total genus	27
structure length	117
sequence length	117
ec nomenclature	ec 2.7.1.154: Phosphatidylinositol-4-phosphate 3-kinase.
pdb deposition date	2005-08-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00787	PX	PX domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1520.10	Alpha Beta	2-Layer Sandwich	PX Domain	Phox-like domain	2ar5A00

2WWEA 4IKDA 1H6HA 2IWLX 2V14A 4PQPA 3HPBA 4PZGA 2V6VA 2L73A 4OXWA 4PQOA 3P0CA 2YPSA 4HASA 4P2IA 4BGJA 1OCSA 2DYBA 3DYTA 2I4KA 4AZ9A 3IQ2A 3FOGA 4P2JA 2REDA 2AR5A 4IKBB 3LUIA 2CSKA 1O7KA 1GD5A 2REAA 2CZOA 4ON3A 1XTEA 4IKBA 1XTNA 2RAIA 2RAJA 1KQ6A 2RAKA 4AKVA 1KMDA 3HPCX 2ETTA 1OCUA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2WWE A;  4IKD A;  1H6H A;  2IWL X;  2V14 A;  4PQP A;  3HPB A;  4PZG A;  2V6V A;  2L73 A;  4OXW A;  4PQO A;  3P0C A;  2YPS A;  4HAS A;  4P2I A;  4BGJ A;  1OCS A;  2DYB A;  3DYT A;  2I4K A;  4AZ9 A;  3IQ2 A;  3FOG A;  4P2J A;  2RED A;  2AR5 A;  4IKB B;  3LUI A;  2CSK A;  1O7K A;  1GD5 A;  2REA A;  2CZO A;  4ON3 A;  1XTE A;  4IKB A;  1XTN A;  2RAI A;  2RAJ A;  1KQ6 A;  2RAK A;  4AKV A;  1KMD A;  3HPC X;  2ETT A;  1OCU A; 
#chains in the Genus database with same CATH topology
 2WWE A;  4IKD A;  1H6H A;  2IWL X;  2V14 A;  4PQP A;  3HPB A;  4PZG A;  2V6V A;  2L73 A;  4OXW A;  4PQO A;  3P0C A;  2YPS A;  4HAS A;  4P2I A;  4BGJ A;  1OCS A;  2DYB A;  3DYT A;  2I4K A;  4AZ9 A;  3IQ2 A;  3FOG A;  4P2J A;  2RED A;  2AR5 A;  4IKB B;  3LUI A;  2CSK A;  1O7K A;  1GD5 A;  2REA A;  2CZO A;  4ON3 A;  1XTE A;  4IKB A;  1XTN A;  2RAI A;  2RAJ A;  1KQ6 A;  2RAK A;  4AKV A;  1KMD A;  3HPC X;  2ETT A;  1OCU A; 
#chains in the Genus database with same CATH homology
 2WWE A;  4IKD A;  1H6H A;  2IWL X;  2V14 A;  4PQP A;  3HPB A;  4PZG A;  2V6V A;  2L73 A;  4OXW A;  4PQO A;  3P0C A;  2YPS A;  4HAS A;  4P2I A;  4BGJ A;  1OCS A;  2DYB A;  3DYT A;  2I4K A;  4AZ9 A;  3IQ2 A;  3FOG A;  4P2J A;  2RED A;  2AR5 A;  4IKB B;  3LUI A;  2CSK A;  1O7K A;  1GD5 A;  2REA A;  2CZO A;  4ON3 A;  1XTE A;  4IKB A;  1XTN A;  2RAI A;  2RAJ A;  1KQ6 A;  2RAK A;  4AKV A;  1KMD A;  3HPC X;  2ETT A;  1OCU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2AR5A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations