2C9WC

Crystal structure of socs-2 in complex with elongin-b and elongin-c at 1.9a resolution
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
96
structure length
80
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMNEVNFREIPSHVLSKVCMYFTYKVRYTEIPEFPIAPEIALELLMAANFLDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
pubmed doi rcsb
molecule tags Transcription regulation
source organism Homo sapiens
molecule keywords SUPPRESSOR OF CYTOKINE SIGNALING 2
total genus 24
structure length 80
sequence length 96
ec nomenclature
pdb deposition date 2005-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 2c9wC00
4U2MA 2ASTA 2YY9A 3ZUNB 3MKSA 4CP3A 5DADA 2VPKA 2P1QA 1LQBB 1BUOA 3ZTCB 4W9KB 3V7DA 5HYWB 1QDVA 2OVQA 2E32B 2A79B 1QDWA 3HVEA 5EUPA 4U2NA 4W9FB 4JTDB 2IZVC 5FTAA 1NN7A 1DSXA 4AJYC 1NEXA 2R9RB 1EOFA 3B84A 3FKCA 3ZNGB 4W9CB 5IBKA 3OGKA 4N9F5 3M52A 4ZOUA 5HZGC 2IF5A 3ZKJB 4BGCA 5A15A 4W9HB 4BKTB 4JTAB 4EOZA 4CXIA 4APFA 3HTMA 5BXDA 4HXIA 2NN2A 5DAFA 1P22B 1EXBE 4B95B 2PPIA 3OGMA 2NZ0B 2IHCA 3DCGB 3ZRCB 1HV2A 5BXBA 1CS3A 1FS2B 3OHVA 3LNMB 3WSOB 4WQOC 1FQVB 3KVTA 3ZTDB 4W9IB 5LLIB 5H7GA 3OHUA 1T1DA 4W9LB 4W9DB 3I3NA 2FNJC 4AWJB 3BIMA 2JZ3C 4UYIA 1VCBB 2P1MA 3E4UA 4B9KE 4B9KB 3C6NA 3M8VA 4CXTA 5H7HA 1EODA 1A68A 4W9GB 1FS1B 5A6RA 3HU6A 4BKSB 4W9EB 2Z8HA 5BO4C 3LBZA 3ZRFB 4U77A 4UIJA 4J8ZA 1LM8C 1R2BA 2I2RA 3HQIA 2P1PA 3C6OA 4W9HH 4CXJA 2ASSA 2Q81A 3L2OA 2C9WC 2P1OA 4W9JB 1R28A 2E31B 1S1GA 3DRZA 3M4TA 4I6JC 2VKPA 5JH5B 1R29A 4JGHC 3GA1A 3LUTB 4JTCB 5BXHA 1LDKD 3OGLA 3HVEB 4AP2A 3M5BA 2OVRA 1EOEA 3C6PA 4CRHA 2MA9C 2P1NA 2OVPA
chains in the Genus database with same CATH superfamily
4U2MA 2ASTA 2YY9A 3ZUNB 3MKSA 4CP3A 5DADA 2VPKA 2P1QA 1LQBB 1BUOA 3ZTCB 4W9KB 3V7DA 5HYWB 1QDVA 2OVQA 2E32B 2A79B 1QDWA 3HVEA 5EUPA 4U2NA 4W9FB 4JTDB 2IZVC 5FTAA 1NN7A 1DSXA 4AJYC 1NEXA 2R9RB 1EOFA 3B84A 3FKCA 3ZNGB 4W9CB 5IBKA 3OGKA 4YY8A 4N9F5 3M52A 4ZOUA 5HZGC 2IF5A 3ZKJB 4BGCA 5A15A 4W9HB 4BKTB 4JTAB 4EOZA 4CXIA 4APFA 3HTMA 3DRYA 5BXDA 4HXIA 2NN2A 5DAFA 1P22B 3DRXA 1EXBE 4B95B 2PPIA 3OGMA 2NZ0B 2IHCA 3DCGB 3ZRCB 1HV2A 5BXBA 1CS3A 1FS2B 3OHVA 3LNMB 3WSOB 4WQOC 1FQVB 3KVTA 3ZTDB 4W9IB 5LLIB 5H7GA 3OHUA 1T1DA 4W9LB 4W9DB 3I3NA 2FNJC 4AWJB 3BIMA 2JZ3C 4UYIA 1VCBB 2P1MA 3E4UA 4B9KE 4B9KB 3C6NA 3M8VA 4CXTA 5H7HA 1EODA 1A68A 4W9GB 1FS1B 5A6RA 3HU6A 4BKSB 4W9EB 2Z8HA 5BO4C 3LBZA 3ZRFB 4U77A 4UIJA 4J8ZA 1LM8C 1R2BA 2I2RA 3HQIA 2P1PA 3C6OA 4W9HH 4CXJA 2ASSA 2Q81A 3L2OA 2C9WC 2P1OA 4W9JB 1R28A 2E31B 1S1GA 3DRZA 3M4TA 4I6JC 2VKPA 5JH5B 1R29A 4JGHC 3GA1A 3LUTB 4JTCB 5BXHA 1LDKD 3OGLA 3HVEB 4AP2A 3M5BA 2OVRA 1EOEA 3C6PA 4CRHA 2MA9C 2P1NA 2OVPA 4ZGCA
chains in the Genus database with same CATH topology
4U2MA 2ASTA 2YY9A 3ZUNB 3MKSA 4CP3A 5DADA 2VPKA 2P1QA 1LQBB 1BUOA 3ZTCB 4W9KB 3V7DA 5HYWB 1QDVA 2OVQA 2E32B 2A79B 1QDWA 3HVEA 5EUPA 4U2NA 4W9FB 4JTDB 2IZVC 5FTAA 1NN7A 1DSXA 4AJYC 1NEXA 2R9RB 1EOFA 3B84A 3FKCA 3ZNGB 4W9CB 5IBKA 3OGKA 4YY8A 4N9F5 3M52A 4ZOUA 5HZGC 2IF5A 3ZKJB 4BGCA 5A15A 4W9HB 4BKTB 4JTAB 4EOZA 4CXIA 4APFA 3HTMA 3DRYA 5BXDA 4HXIA 2NN2A 5DAFA 1P22B 3DRXA 1EXBE 4B95B 2PPIA 3OGMA 2NZ0B 2IHCA 3DCGB 3ZRCB 1HV2A 5BXBA 1CS3A 1FS2B 3OHVA 3LNMB 3WSOB 4WQOC 1FQVB 3KVTA 3ZTDB 4W9IB 5LLIB 5H7GA 3OHUA 1T1DA 4W9LB 4W9DB 3I3NA 2FNJC 4AWJB 3BIMA 2JZ3C 4UYIA 1VCBB 2P1MA 3E4UA 4B9KE 4B9KB 3C6NA 3M8VA 4CXTA 5H7HA 1EODA 1A68A 4W9GB 1FS1B 5A6RA 3HU6A 4BKSB 4W9EB 2Z8HA 5BO4C 3LBZA 3ZRFB 4U77A 4UIJA 4J8ZA 1LM8C 1R2BA 2I2RA 3HQIA 2P1PA 3C6OA 4W9HH 4CXJA 2ASSA 2Q81A 3L2OA 2C9WC 2P1OA 4W9JB 1R28A 2E31B 1S1GA 3DRZA 3M4TA 4I6JC 2VKPA 5JH5B 1R29A 4JGHC 3GA1A 3LUTB 4JTCB 5BXHA 1LDKD 3OGLA 3HVEB 4AP2A 3M5BA 2OVRA 1EOEA 3C6PA 4CRHA 2MA9C 2P1NA 2OVPA 4ZGCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U2M A;  2AST A;  2YY9 A;  3ZUN B;  3MKS A;  4CP3 A;  5DAD A;  2VPK A;  2P1Q A;  1LQB B;  1BUO A;  3ZTC B;  4W9K B;  3V7D A;  5HYW B;  1QDV A;  2OVQ A;  2E32 B;  2A79 B;  1QDW A;  3HVE A;  5EUP A;  4U2N A;  4W9F B;  4JTD B;  2IZV C;  5FTA A;  1NN7 A;  1DSX A;  4AJY C;  1NEX A;  2R9R B;  1EOF A;  3B84 A;  3FKC A;  3ZNG B;  4W9C B;  5IBK A;  3OGK A;  4N9F 5;  3M52 A;  4ZOU A;  5HZG C;  2IF5 A;  3ZKJ B;  4BGC A;  5A15 A;  4W9H B;  4BKT B;  4JTA B;  4EOZ A;  4CXI A;  4APF A;  3HTM A;  5BXD A;  4HXI A;  2NN2 A;  5DAF A;  1P22 B;  1EXB E;  4B95 B;  2PPI A;  3OGM A;  2NZ0 B;  2IHC A;  3DCG B;  3ZRC B;  1HV2 A;  5BXB A;  1CS3 A;  1FS2 B;  3OHV A;  3LNM B;  3WSO B;  4WQO C;  1FQV B;  3KVT A;  3ZTD B;  4W9I B;  5LLI B;  5H7G A;  3OHU A;  1T1D A;  4W9L B;  4W9D B;  3I3N A;  2FNJ C;  4AWJ B;  3BIM A;  2JZ3 C;  4UYI A;  1VCB B;  2P1M A;  3E4U A;  4B9K E;  4B9K B;  3C6N A;  3M8V A;  4CXT A;  5H7H A;  1EOD A;  1A68 A;  4W9G B;  1FS1 B;  5A6R A;  3HU6 A;  4BKS B;  4W9E B;  2Z8H A;  5BO4 C;  3LBZ A;  3ZRF B;  4U77 A;  4UIJ A;  4J8Z A;  1LM8 C;  1R2B A;  2I2R A;  3HQI A;  2P1P A;  3C6O A;  4W9H H;  4CXJ A;  2ASS A;  2Q81 A;  3L2O A;  2C9W C;  2P1O A;  4W9J B;  1R28 A;  2E31 B;  1S1G A;  3DRZ A;  3M4T A;  4I6J C;  2VKP A;  5JH5 B;  1R29 A;  4JGH C;  3GA1 A;  3LUT B;  4JTC B;  5BXH A;  1LDK D;  3OGL A;  3HVE B;  4AP2 A;  3M5B A;  2OVR A;  1EOE A;  3C6P A;  4CRH A;  2MA9 C;  2P1N A;  2OVP A; 
#chains in the Genus database with same CATH topology
 4U2M A;  2AST A;  2YY9 A;  3ZUN B;  3MKS A;  4CP3 A;  5DAD A;  2VPK A;  2P1Q A;  1LQB B;  1BUO A;  3ZTC B;  4W9K B;  3V7D A;  5HYW B;  1QDV A;  2OVQ A;  2E32 B;  2A79 B;  1QDW A;  3HVE A;  5EUP A;  4U2N A;  4W9F B;  4JTD B;  2IZV C;  5FTA A;  1NN7 A;  1DSX A;  4AJY C;  1NEX A;  2R9R B;  1EOF A;  3B84 A;  3FKC A;  3ZNG B;  4W9C B;  5IBK A;  3OGK A;  4YY8 A;  4N9F 5;  3M52 A;  4ZOU A;  5HZG C;  2IF5 A;  3ZKJ B;  4BGC A;  5A15 A;  4W9H B;  4BKT B;  4JTA B;  4EOZ A;  4CXI A;  4APF A;  3HTM A;  3DRY A;  5BXD A;  4HXI A;  2NN2 A;  5DAF A;  1P22 B;  3DRX A;  1EXB E;  4B95 B;  2PPI A;  3OGM A;  2NZ0 B;  2IHC A;  3DCG B;  3ZRC B;  1HV2 A;  5BXB A;  1CS3 A;  1FS2 B;  3OHV A;  3LNM B;  3WSO B;  4WQO C;  1FQV B;  3KVT A;  3ZTD B;  4W9I B;  5LLI B;  5H7G A;  3OHU A;  1T1D A;  4W9L B;  4W9D B;  3I3N A;  2FNJ C;  4AWJ B;  3BIM A;  2JZ3 C;  4UYI A;  1VCB B;  2P1M A;  3E4U A;  4B9K E;  4B9K B;  3C6N A;  3M8V A;  4CXT A;  5H7H A;  1EOD A;  1A68 A;  4W9G B;  1FS1 B;  5A6R A;  3HU6 A;  4BKS B;  4W9E B;  2Z8H A;  5BO4 C;  3LBZ A;  3ZRF B;  4U77 A;  4UIJ A;  4J8Z A;  1LM8 C;  1R2B A;  2I2R A;  3HQI A;  2P1P A;  3C6O A;  4W9H H;  4CXJ A;  2ASS A;  2Q81 A;  3L2O A;  2C9W C;  2P1O A;  4W9J B;  1R28 A;  2E31 B;  1S1G A;  3DRZ A;  3M4T A;  4I6J C;  2VKP A;  5JH5 B;  1R29 A;  4JGH C;  3GA1 A;  3LUT B;  4JTC B;  5BXH A;  1LDK D;  3OGL A;  3HVE B;  4AP2 A;  3M5B A;  2OVR A;  1EOE A;  3C6P A;  4CRH A;  2MA9 C;  2P1N A;  2OVP A;  4ZGC A; 
#chains in the Genus database with same CATH homology
 4U2M A;  2AST A;  2YY9 A;  3ZUN B;  3MKS A;  4CP3 A;  5DAD A;  2VPK A;  2P1Q A;  1LQB B;  1BUO A;  3ZTC B;  4W9K B;  3V7D A;  5HYW B;  1QDV A;  2OVQ A;  2E32 B;  2A79 B;  1QDW A;  3HVE A;  5EUP A;  4U2N A;  4W9F B;  4JTD B;  2IZV C;  5FTA A;  1NN7 A;  1DSX A;  4AJY C;  1NEX A;  2R9R B;  1EOF A;  3B84 A;  3FKC A;  3ZNG B;  4W9C B;  5IBK A;  3OGK A;  4YY8 A;  4N9F 5;  3M52 A;  4ZOU A;  5HZG C;  2IF5 A;  3ZKJ B;  4BGC A;  5A15 A;  4W9H B;  4BKT B;  4JTA B;  4EOZ A;  4CXI A;  4APF A;  3HTM A;  3DRY A;  5BXD A;  4HXI A;  2NN2 A;  5DAF A;  1P22 B;  3DRX A;  1EXB E;  4B95 B;  2PPI A;  3OGM A;  2NZ0 B;  2IHC A;  3DCG B;  3ZRC B;  1HV2 A;  5BXB A;  1CS3 A;  1FS2 B;  3OHV A;  3LNM B;  3WSO B;  4WQO C;  1FQV B;  3KVT A;  3ZTD B;  4W9I B;  5LLI B;  5H7G A;  3OHU A;  1T1D A;  4W9L B;  4W9D B;  3I3N A;  2FNJ C;  4AWJ B;  3BIM A;  2JZ3 C;  4UYI A;  1VCB B;  2P1M A;  3E4U A;  4B9K E;  4B9K B;  3C6N A;  3M8V A;  4CXT A;  5H7H A;  1EOD A;  1A68 A;  4W9G B;  1FS1 B;  5A6R A;  3HU6 A;  4BKS B;  4W9E B;  2Z8H A;  5BO4 C;  3LBZ A;  3ZRF B;  4U77 A;  4UIJ A;  4J8Z A;  1LM8 C;  1R2B A;  2I2R A;  3HQI A;  2P1P A;  3C6O A;  4W9H H;  4CXJ A;  2ASS A;  2Q81 A;  3L2O A;  2C9W C;  2P1O A;  4W9J B;  1R28 A;  2E31 B;  1S1G A;  3DRZ A;  3M4T A;  4I6J C;  2VKP A;  5JH5 B;  1R29 A;  4JGH C;  3GA1 A;  3LUT B;  4JTC B;  5BXH A;  1LDK D;  3OGL A;  3HVE B;  4AP2 A;  3M5B A;  2OVR A;  1EOE A;  3C6P A;  4CRH A;  2MA9 C;  2P1N A;  2OVP A;  4ZGC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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