2I4KA

Solution structure of the px domain of sorting nexin 1
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
128
structure length
128
Chain Sequence
QFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Determinants of the Endosomal Localization of Sorting Nexin 1
pubmed doi rcsb
molecule tags Protein transport
source organism Homo sapiens
molecule keywords Sorting nexin-1
total genus 18
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2006-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 2i4kA00
1XTEA 2V6VA 3IQ2A 4P2IA 4BGJA 2AR5A 2L73A 3FOGA 1OCUA 3DYTA 2I4KA 4IKBB 1OCSA 2RAIA 1H6HA 4P2JA 4PZGA 4OXWA 2IWLX 2REDA 4IKBA 3LUIA 1KMDA 2YPSA 4AZ9A 4HASA 4PQPA 2ETTA 2RAJA 2V14A 2DYBA 1XTNA 1O7KA 2CSKA 4PQOA 3HPBA 2WWEA 1KQ6A 2REAA 3HPCX 4AKVA 1GD5A 2CZOA 4ON3A 2RAKA 4IKDA 3P0CA
chains in the Genus database with same CATH superfamily
1XTEA 2V6VA 3IQ2A 4P2IA 4BGJA 2AR5A 2L73A 3FOGA 1OCUA 3DYTA 2I4KA 4IKBB 1OCSA 2RAIA 1H6HA 4P2JA 4PZGA 4OXWA 2IWLX 2REDA 4IKBA 3LUIA 1KMDA 2YPSA 4AZ9A 4HASA 4PQPA 2ETTA 2RAJA 2V14A 2DYBA 1XTNA 1O7KA 2CSKA 4PQOA 3HPBA 2WWEA 1KQ6A 2REAA 3HPCX 4AKVA 1GD5A 2CZOA 4ON3A 2RAKA 4IKDA 3P0CA
chains in the Genus database with same CATH topology
1XTEA 2V6VA 3IQ2A 4P2IA 4BGJA 2AR5A 2L73A 3FOGA 1OCUA 3DYTA 2I4KA 4IKBB 1OCSA 2RAIA 1H6HA 4P2JA 4PZGA 4OXWA 2IWLX 2REDA 4IKBA 3LUIA 1KMDA 2YPSA 4AZ9A 4HASA 4PQPA 2ETTA 2RAJA 2V14A 2DYBA 1XTNA 1O7KA 2CSKA 4PQOA 3HPBA 2WWEA 1KQ6A 2REAA 3HPCX 4AKVA 1GD5A 2CZOA 4ON3A 2RAKA 4IKDA 3P0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XTE A;  2V6V A;  3IQ2 A;  4P2I A;  4BGJ A;  2AR5 A;  2L73 A;  3FOG A;  1OCU A;  3DYT A;  2I4K A;  4IKB B;  1OCS A;  2RAI A;  1H6H A;  4P2J A;  4PZG A;  4OXW A;  2IWL X;  2RED A;  4IKB A;  3LUI A;  1KMD A;  2YPS A;  4AZ9 A;  4HAS A;  4PQP A;  2ETT A;  2RAJ A;  2V14 A;  2DYB A;  1XTN A;  1O7K A;  2CSK A;  4PQO A;  3HPB A;  2WWE A;  1KQ6 A;  2REA A;  3HPC X;  4AKV A;  1GD5 A;  2CZO A;  4ON3 A;  2RAK A;  4IKD A;  3P0C A; 
#chains in the Genus database with same CATH topology
 1XTE A;  2V6V A;  3IQ2 A;  4P2I A;  4BGJ A;  2AR5 A;  2L73 A;  3FOG A;  1OCU A;  3DYT A;  2I4K A;  4IKB B;  1OCS A;  2RAI A;  1H6H A;  4P2J A;  4PZG A;  4OXW A;  2IWL X;  2RED A;  4IKB A;  3LUI A;  1KMD A;  2YPS A;  4AZ9 A;  4HAS A;  4PQP A;  2ETT A;  2RAJ A;  2V14 A;  2DYB A;  1XTN A;  1O7K A;  2CSK A;  4PQO A;  3HPB A;  2WWE A;  1KQ6 A;  2REA A;  3HPC X;  4AKV A;  1GD5 A;  2CZO A;  4ON3 A;  2RAK A;  4IKD A;  3P0C A; 
#chains in the Genus database with same CATH homology
 1XTE A;  2V6V A;  3IQ2 A;  4P2I A;  4BGJ A;  2AR5 A;  2L73 A;  3FOG A;  1OCU A;  3DYT A;  2I4K A;  4IKB B;  1OCS A;  2RAI A;  1H6H A;  4P2J A;  4PZG A;  4OXW A;  2IWL X;  2RED A;  4IKB A;  3LUI A;  1KMD A;  2YPS A;  4AZ9 A;  4HAS A;  4PQP A;  2ETT A;  2RAJ A;  2V14 A;  2DYB A;  1XTN A;  1O7K A;  2CSK A;  4PQO A;  3HPB A;  2WWE A;  1KQ6 A;  2REA A;  3HPC X;  4AKV A;  1GD5 A;  2CZO A;  4ON3 A;  2RAK A;  4IKD A;  3P0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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