2OVPA

Structure of the skp1-fbw7 complex
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
144
structure length
134
Chain Sequence
PSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDPVPLPNVNAAILKKVIQWCTHHDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
pubmed doi rcsb
molecule tags Transcription/cell cycle
source organism Homo sapiens
molecule keywords S-phase kinase-associated protein 1A
total genus 45
structure length 134
sequence length 144
ec nomenclature
pdb deposition date 2007-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01466 Skp1 Skp1 family, dimerisation domain
A PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 2ovpA00
1S1GA 1EOFA 1LM8C 1QDWA 1T1DA 3HTMA 3C6NA 1EODA 3B84A 4B9KE 4BKTB 1FS2B 2NZ0B 4B9KB 3HVEA 3M5BA 4AJYC 5BXHA 5H7GA 4W9IB 3ZRCB 5BO4C 4JTAB 2IZVC 3C6OA 2C9WC 1FQVB 4W9EB 3HQIA 4W9HB 4I6JC 4ZOUA 4BGCA 1FS1B 1R2BA 4W9LB 2VPKA 2YY9A 4BKSB 1R29A 4UYIA 5DAFA 3ZUNB 2ASSA 4J8ZA 4U77A 2P1PA 4N9F5 4CXTA 4U2MA 4W9GB 3V7DA 3ZNGB 5BXDA 1QDVA 3M8VA 3E4UA 1VCBB 2P1MA 3ZRFB 2P1OA 2NN2A 4AP2A 1EXBE 2E31B 3BIMA 3DRZA 1LQBB 2IHCA 5FTAA 2OVQA 3GA1A 5EUPA 3HVEB 5JH5B 3LNMB 1A68A 2R9RB 3ZTCB 1EOEA 3LBZA 4HXIA 4U2NA 4JTCB 2P1QA 2PPIA 2VKPA 2E32B 2IF5A 4CXIA 1CS3A 5HYWB 4JGHC 5BXBA 2FNJC 3HU6A 4B95B 1HV2A 2I2RA 3OGLA 5H7HA 4W9KB 2JZ3C 3ZTDB 2ASTA 2OVPA 1LDKD 3OGKA 2P1NA 1DSXA 3KVTA 1BUOA 3L2OA 3ZKJB 4APFA 5A6RA 2OVRA 3MKSA 4EOZA 3M52A 4W9HH 1NEXA 4AWJB 1R28A 3OHUA 3C6PA 4W9JB 3DCGB 3FKCA 4CP3A 1P22B 3M4TA 4CXJA 4WQOC 5LLIB 2A79B 5HZGC 3I3NA 5DADA 4CRHA 4W9FB 4W9DB 2MA9C 4JTDB 3OHVA 5A15A 2Z8HA 1NN7A 4W9CB 2Q81A 3LUTB 3OGMA 4UIJA 3WSOB 5IBKA
chains in the Genus database with same CATH superfamily
1S1GA 1EOFA 1LM8C 1QDWA 1T1DA 3HTMA 3C6NA 1EODA 3B84A 4B9KE 4BKTB 1FS2B 2NZ0B 4B9KB 3HVEA 3M5BA 4AJYC 5BXHA 5H7GA 4W9IB 3ZRCB 4ZGCA 5BO4C 4JTAB 2IZVC 3C6OA 2C9WC 1FQVB 4W9EB 3HQIA 4W9HB 4I6JC 4ZOUA 4BGCA 1FS1B 1R2BA 4W9LB 2VPKA 2YY9A 4BKSB 1R29A 4UYIA 5DAFA 3ZUNB 2ASSA 4J8ZA 4U77A 2P1PA 4N9F5 4CXTA 4U2MA 4W9GB 3V7DA 3ZNGB 5BXDA 1QDVA 3M8VA 3E4UA 1VCBB 2P1MA 3ZRFB 3DRXA 2P1OA 2NN2A 4AP2A 1EXBE 2E31B 3BIMA 3DRZA 1LQBB 2IHCA 5FTAA 2OVQA 3GA1A 5EUPA 3HVEB 5JH5B 3LNMB 1A68A 2R9RB 3ZTCB 1EOEA 3LBZA 4HXIA 4U2NA 4JTCB 2P1QA 2PPIA 2VKPA 2E32B 2IF5A 4CXIA 1CS3A 5HYWB 4JGHC 5BXBA 2FNJC 3HU6A 4B95B 1HV2A 2I2RA 3OGLA 5H7HA 4W9KB 2JZ3C 3ZTDB 4YY8A 2ASTA 2OVPA 1LDKD 3OGKA 2P1NA 1DSXA 3KVTA 1BUOA 3L2OA 3ZKJB 4APFA 5A6RA 2OVRA 3MKSA 4EOZA 3M52A 3DRYA 4W9HH 1NEXA 4AWJB 1R28A 3OHUA 3C6PA 4W9JB 3DCGB 3FKCA 4CP3A 1P22B 3M4TA 4CXJA 4WQOC 5LLIB 2A79B 5HZGC 3I3NA 5DADA 4CRHA 4W9FB 4W9DB 2MA9C 4JTDB 3OHVA 5A15A 2Z8HA 1NN7A 4W9CB 2Q81A 3LUTB 3OGMA 4UIJA 3WSOB 5IBKA
chains in the Genus database with same CATH topology
1S1GA 1EOFA 1LM8C 1QDWA 1T1DA 3HTMA 3C6NA 1EODA 3B84A 4B9KE 4BKTB 1FS2B 2NZ0B 4B9KB 3HVEA 3M5BA 4AJYC 5BXHA 5H7GA 4W9IB 3ZRCB 4ZGCA 5BO4C 4JTAB 2IZVC 3C6OA 2C9WC 1FQVB 4W9EB 3HQIA 4W9HB 4I6JC 4ZOUA 4BGCA 1FS1B 1R2BA 4W9LB 2VPKA 2YY9A 4BKSB 1R29A 4UYIA 5DAFA 3ZUNB 2ASSA 4J8ZA 4U77A 2P1PA 4N9F5 4CXTA 4U2MA 4W9GB 3V7DA 3ZNGB 5BXDA 1QDVA 3M8VA 3E4UA 1VCBB 2P1MA 3ZRFB 3DRXA 2P1OA 2NN2A 4AP2A 1EXBE 2E31B 3BIMA 3DRZA 1LQBB 2IHCA 5FTAA 2OVQA 3GA1A 5EUPA 3HVEB 5JH5B 3LNMB 1A68A 2R9RB 3ZTCB 1EOEA 3LBZA 4HXIA 4U2NA 4JTCB 2P1QA 2PPIA 2VKPA 2E32B 2IF5A 4CXIA 1CS3A 5HYWB 4JGHC 5BXBA 2FNJC 3HU6A 4B95B 1HV2A 2I2RA 3OGLA 5H7HA 4W9KB 2JZ3C 3ZTDB 4YY8A 2ASTA 2OVPA 1LDKD 3OGKA 2P1NA 1DSXA 3KVTA 1BUOA 3L2OA 3ZKJB 4APFA 5A6RA 2OVRA 3MKSA 4EOZA 3M52A 3DRYA 4W9HH 1NEXA 4AWJB 1R28A 3OHUA 3C6PA 4W9JB 3DCGB 3FKCA 4CP3A 1P22B 3M4TA 4CXJA 4WQOC 5LLIB 2A79B 5HZGC 3I3NA 5DADA 4CRHA 4W9FB 4W9DB 2MA9C 4JTDB 3OHVA 5A15A 2Z8HA 1NN7A 4W9CB 2Q81A 3LUTB 3OGMA 4UIJA 3WSOB 5IBKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S1G A;  1EOF A;  1LM8 C;  1QDW A;  1T1D A;  3HTM A;  3C6N A;  1EOD A;  3B84 A;  4B9K E;  4BKT B;  1FS2 B;  2NZ0 B;  4B9K B;  3HVE A;  3M5B A;  4AJY C;  5BXH A;  5H7G A;  4W9I B;  3ZRC B;  5BO4 C;  4JTA B;  2IZV C;  3C6O A;  2C9W C;  1FQV B;  4W9E B;  3HQI A;  4W9H B;  4I6J C;  4ZOU A;  4BGC A;  1FS1 B;  1R2B A;  4W9L B;  2VPK A;  2YY9 A;  4BKS B;  1R29 A;  4UYI A;  5DAF A;  3ZUN B;  2ASS A;  4J8Z A;  4U77 A;  2P1P A;  4N9F 5;  4CXT A;  4U2M A;  4W9G B;  3V7D A;  3ZNG B;  5BXD A;  1QDV A;  3M8V A;  3E4U A;  1VCB B;  2P1M A;  3ZRF B;  2P1O A;  2NN2 A;  4AP2 A;  1EXB E;  2E31 B;  3BIM A;  3DRZ A;  1LQB B;  2IHC A;  5FTA A;  2OVQ A;  3GA1 A;  5EUP A;  3HVE B;  5JH5 B;  3LNM B;  1A68 A;  2R9R B;  3ZTC B;  1EOE A;  3LBZ A;  4HXI A;  4U2N A;  4JTC B;  2P1Q A;  2PPI A;  2VKP A;  2E32 B;  2IF5 A;  4CXI A;  1CS3 A;  5HYW B;  4JGH C;  5BXB A;  2FNJ C;  3HU6 A;  4B95 B;  1HV2 A;  2I2R A;  3OGL A;  5H7H A;  4W9K B;  2JZ3 C;  3ZTD B;  2AST A;  2OVP A;  1LDK D;  3OGK A;  2P1N A;  1DSX A;  3KVT A;  1BUO A;  3L2O A;  3ZKJ B;  4APF A;  5A6R A;  2OVR A;  3MKS A;  4EOZ A;  3M52 A;  4W9H H;  1NEX A;  4AWJ B;  1R28 A;  3OHU A;  3C6P A;  4W9J B;  3DCG B;  3FKC A;  4CP3 A;  1P22 B;  3M4T A;  4CXJ A;  4WQO C;  5LLI B;  2A79 B;  5HZG C;  3I3N A;  5DAD A;  4CRH A;  4W9F B;  4W9D B;  2MA9 C;  4JTD B;  3OHV A;  5A15 A;  2Z8H A;  1NN7 A;  4W9C B;  2Q81 A;  3LUT B;  3OGM A;  4UIJ A;  3WSO B;  5IBK A; 
#chains in the Genus database with same CATH topology
 1S1G A;  1EOF A;  1LM8 C;  1QDW A;  1T1D A;  3HTM A;  3C6N A;  1EOD A;  3B84 A;  4B9K E;  4BKT B;  1FS2 B;  2NZ0 B;  4B9K B;  3HVE A;  3M5B A;  4AJY C;  5BXH A;  5H7G A;  4W9I B;  3ZRC B;  4ZGC A;  5BO4 C;  4JTA B;  2IZV C;  3C6O A;  2C9W C;  1FQV B;  4W9E B;  3HQI A;  4W9H B;  4I6J C;  4ZOU A;  4BGC A;  1FS1 B;  1R2B A;  4W9L B;  2VPK A;  2YY9 A;  4BKS B;  1R29 A;  4UYI A;  5DAF A;  3ZUN B;  2ASS A;  4J8Z A;  4U77 A;  2P1P A;  4N9F 5;  4CXT A;  4U2M A;  4W9G B;  3V7D A;  3ZNG B;  5BXD A;  1QDV A;  3M8V A;  3E4U A;  1VCB B;  2P1M A;  3ZRF B;  3DRX A;  2P1O A;  2NN2 A;  4AP2 A;  1EXB E;  2E31 B;  3BIM A;  3DRZ A;  1LQB B;  2IHC A;  5FTA A;  2OVQ A;  3GA1 A;  5EUP A;  3HVE B;  5JH5 B;  3LNM B;  1A68 A;  2R9R B;  3ZTC B;  1EOE A;  3LBZ A;  4HXI A;  4U2N A;  4JTC B;  2P1Q A;  2PPI A;  2VKP A;  2E32 B;  2IF5 A;  4CXI A;  1CS3 A;  5HYW B;  4JGH C;  5BXB A;  2FNJ C;  3HU6 A;  4B95 B;  1HV2 A;  2I2R A;  3OGL A;  5H7H A;  4W9K B;  2JZ3 C;  3ZTD B;  4YY8 A;  2AST A;  2OVP A;  1LDK D;  3OGK A;  2P1N A;  1DSX A;  3KVT A;  1BUO A;  3L2O A;  3ZKJ B;  4APF A;  5A6R A;  2OVR A;  3MKS A;  4EOZ A;  3M52 A;  3DRY A;  4W9H H;  1NEX A;  4AWJ B;  1R28 A;  3OHU A;  3C6P A;  4W9J B;  3DCG B;  3FKC A;  4CP3 A;  1P22 B;  3M4T A;  4CXJ A;  4WQO C;  5LLI B;  2A79 B;  5HZG C;  3I3N A;  5DAD A;  4CRH A;  4W9F B;  4W9D B;  2MA9 C;  4JTD B;  3OHV A;  5A15 A;  2Z8H A;  1NN7 A;  4W9C B;  2Q81 A;  3LUT B;  3OGM A;  4UIJ A;  3WSO B;  5IBK A; 
#chains in the Genus database with same CATH homology
 1S1G A;  1EOF A;  1LM8 C;  1QDW A;  1T1D A;  3HTM A;  3C6N A;  1EOD A;  3B84 A;  4B9K E;  4BKT B;  1FS2 B;  2NZ0 B;  4B9K B;  3HVE A;  3M5B A;  4AJY C;  5BXH A;  5H7G A;  4W9I B;  3ZRC B;  4ZGC A;  5BO4 C;  4JTA B;  2IZV C;  3C6O A;  2C9W C;  1FQV B;  4W9E B;  3HQI A;  4W9H B;  4I6J C;  4ZOU A;  4BGC A;  1FS1 B;  1R2B A;  4W9L B;  2VPK A;  2YY9 A;  4BKS B;  1R29 A;  4UYI A;  5DAF A;  3ZUN B;  2ASS A;  4J8Z A;  4U77 A;  2P1P A;  4N9F 5;  4CXT A;  4U2M A;  4W9G B;  3V7D A;  3ZNG B;  5BXD A;  1QDV A;  3M8V A;  3E4U A;  1VCB B;  2P1M A;  3ZRF B;  3DRX A;  2P1O A;  2NN2 A;  4AP2 A;  1EXB E;  2E31 B;  3BIM A;  3DRZ A;  1LQB B;  2IHC A;  5FTA A;  2OVQ A;  3GA1 A;  5EUP A;  3HVE B;  5JH5 B;  3LNM B;  1A68 A;  2R9R B;  3ZTC B;  1EOE A;  3LBZ A;  4HXI A;  4U2N A;  4JTC B;  2P1Q A;  2PPI A;  2VKP A;  2E32 B;  2IF5 A;  4CXI A;  1CS3 A;  5HYW B;  4JGH C;  5BXB A;  2FNJ C;  3HU6 A;  4B95 B;  1HV2 A;  2I2R A;  3OGL A;  5H7H A;  4W9K B;  2JZ3 C;  3ZTD B;  4YY8 A;  2AST A;  2OVP A;  1LDK D;  3OGK A;  2P1N A;  1DSX A;  3KVT A;  1BUO A;  3L2O A;  3ZKJ B;  4APF A;  5A6R A;  2OVR A;  3MKS A;  4EOZ A;  3M52 A;  3DRY A;  4W9H H;  1NEX A;  4AWJ B;  1R28 A;  3OHU A;  3C6P A;  4W9J B;  3DCG B;  3FKC A;  4CP3 A;  1P22 B;  3M4T A;  4CXJ A;  4WQO C;  5LLI B;  2A79 B;  5HZG C;  3I3N A;  5DAD A;  4CRH A;  4W9F B;  4W9D B;  2MA9 C;  4JTD B;  3OHV A;  5A15 A;  2Z8H A;  1NN7 A;  4W9C B;  2Q81 A;  3LUT B;  3OGM A;  4UIJ A;  3WSO B;  5IBK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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