2OVPA

Structure of the skp1-fbw7 complex
Total Genus 45

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
144
structure length
134
Chain Sequence
PSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDPVPLPNVNAAILKKVIQWCTHHDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Transcription/cell cycle
source organism Homo sapiens
publication title Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
pubmed doi rcsb
molecule keywords S-phase kinase-associated protein 1A
total genus 45
structure length 134
sequence length 144
ec nomenclature
pdb deposition date 2007-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01466 Skp1 Skp1 family, dimerisation domain
A PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 2ovpA00
4JTAB 2P1NA 4JTDB 2ASSA 2VPKA 3C6OA 4N9F5 5IBKA 2E31B 3OGLA 2C9WC 2OVQA 3LUTB 1HV2A 3ZTCB 4CRHA 4CXJA 4U2NA 2P1QA 4W9HH 3HU6A 1DSXA 5HZGC 5A15A 3C6NA 5BXDA 3ZKJB 1P22B 3ZTDB 1EODA 1EXBE 3E4UA 2PPIA 3C6PA 2NN2A 4WQOC 2YY9A 3M4TA 1EOEA 3V7DA 1R2BA 2IF5A 2P1OA 2OVPA 4EOZA 4JTCB 5EUPA 4AWJB 1EOFA 1FQVB 3KVTA 3WSOB 4APFA 2IHCA 3DRZA 3HVEA 5A6RA 1T1DA 3M8VA 3B84A 4W9LB 1S1GA 4J8ZA 2OVRA 4W9KB 4AJYC 2P1PA 3OHUA 4HXIA 1QDVA 1NEXA 3FKCA 4U77A 4BKTB 5DAFA 4CXIA 3M5BA 4W9FB 4CXTA 4I6JC 5H7HA 3I3NA 1NN7A 1VCBB 5JH5B 3HQIA 2JZ3C 2A79B 1FS2B 4W9DB 2R9RB 4W9EB 3LNMB 3BIMA 3ZUNB 4BGCA 2Q81A 4JGHC 2VKPA 4UYIA 3OGKA 3M52A 2IZVC 4W9HB 4W9CB 3L2OA 1A68A 5HYWB 4W9JB 4BKSB 2E32B 4W9GB 1QDWA 5BO4C 2MA9C 4B9KE 1CS3A 4B95B 1R28A 1BUOA 4CP3A 2FNJC 4UIJA 4ZOUA 1LM8C 2Z8HA 5FTAA 3LBZA 1LQBB 4B9KB 3OGMA 4AP2A 3ZNGB 3HVEB 5LLIB 3OHVA 3ZRCB 5DADA 1LDKD 2ASTA 2I2RA 2NZ0B 3DCGB 3GA1A 4W9IB 3ZRFB 1R29A 5BXBA 3HTMA 2P1MA 5H7GA 4U2MA 1FS1B 5BXHA 3MKSA
chains in the Genus database with same CATH superfamily
4JTAB 2P1NA 4JTDB 2ASSA 2VPKA 3C6OA 4N9F5 5IBKA 2E31B 3OGLA 2C9WC 2OVQA 3LUTB 1HV2A 3ZTCB 4CRHA 4CXJA 4U2NA 2P1QA 4W9HH 3HU6A 1DSXA 5HZGC 5A15A 3C6NA 5BXDA 3ZKJB 1P22B 3ZTDB 1EODA 1EXBE 3E4UA 2PPIA 3C6PA 2NN2A 4WQOC 2YY9A 3M4TA 1EOEA 3V7DA 1R2BA 2IF5A 2P1OA 2OVPA 4EOZA 4JTCB 5EUPA 4AWJB 1EOFA 1FQVB 3KVTA 3WSOB 4APFA 2IHCA 3DRZA 3HVEA 5A6RA 4YY8A 1T1DA 3M8VA 3B84A 4W9LB 1S1GA 4J8ZA 4ZGCA 2OVRA 4W9KB 4AJYC 2P1PA 3OHUA 4HXIA 1QDVA 1NEXA 3FKCA 4U77A 4BKTB 5DAFA 4CXIA 3M5BA 4W9FB 4CXTA 4I6JC 5H7HA 3I3NA 1NN7A 1VCBB 5JH5B 3HQIA 2JZ3C 2A79B 1FS2B 4W9DB 2R9RB 4W9EB 3LNMB 3BIMA 3ZUNB 3DRYA 4BGCA 2Q81A 4JGHC 2VKPA 4UYIA 3OGKA 3M52A 2IZVC 4W9HB 4W9CB 3L2OA 1A68A 5HYWB 4W9JB 4BKSB 2E32B 4W9GB 1QDWA 5BO4C 2MA9C 4B9KE 1CS3A 4B95B 1R28A 1BUOA 4CP3A 2FNJC 4UIJA 4ZOUA 1LM8C 2Z8HA 5FTAA 3LBZA 1LQBB 4B9KB 3OGMA 4AP2A 3ZNGB 3HVEB 5LLIB 3OHVA 3ZRCB 5DADA 1LDKD 2ASTA 2I2RA 2NZ0B 3DCGB 3GA1A 4W9IB 3ZRFB 1R29A 5BXBA 3DRXA 3HTMA 2P1MA 5H7GA 4U2MA 1FS1B 5BXHA 3MKSA
chains in the Genus database with same CATH topology
4JTAB 2P1NA 4JTDB 2ASSA 2VPKA 3C6OA 4N9F5 5IBKA 2E31B 3OGLA 2C9WC 2OVQA 3LUTB 1HV2A 3ZTCB 4CRHA 4CXJA 4U2NA 2P1QA 4W9HH 3HU6A 1DSXA 5HZGC 5A15A 3C6NA 5BXDA 3ZKJB 1P22B 3ZTDB 1EODA 1EXBE 3E4UA 2PPIA 3C6PA 2NN2A 4WQOC 2YY9A 3M4TA 1EOEA 3V7DA 1R2BA 2IF5A 2P1OA 2OVPA 4EOZA 4JTCB 5EUPA 4AWJB 1EOFA 1FQVB 3KVTA 3WSOB 4APFA 2IHCA 3DRZA 3HVEA 5A6RA 4YY8A 1T1DA 3M8VA 3B84A 4W9LB 1S1GA 4J8ZA 4ZGCA 2OVRA 4W9KB 4AJYC 2P1PA 3OHUA 4HXIA 1QDVA 1NEXA 3FKCA 4U77A 4BKTB 5DAFA 4CXIA 3M5BA 4W9FB 4CXTA 4I6JC 5H7HA 3I3NA 1NN7A 1VCBB 5JH5B 3HQIA 2JZ3C 2A79B 1FS2B 4W9DB 2R9RB 4W9EB 3LNMB 3BIMA 3ZUNB 3DRYA 4BGCA 2Q81A 4JGHC 2VKPA 4UYIA 3OGKA 3M52A 2IZVC 4W9HB 4W9CB 3L2OA 1A68A 5HYWB 4W9JB 4BKSB 2E32B 4W9GB 1QDWA 5BO4C 2MA9C 4B9KE 1CS3A 4B95B 1R28A 1BUOA 4CP3A 2FNJC 4UIJA 4ZOUA 1LM8C 2Z8HA 5FTAA 3LBZA 1LQBB 4B9KB 3OGMA 4AP2A 3ZNGB 3HVEB 5LLIB 3OHVA 3ZRCB 5DADA 1LDKD 2ASTA 2I2RA 2NZ0B 3DCGB 3GA1A 4W9IB 3ZRFB 1R29A 5BXBA 3DRXA 3HTMA 2P1MA 5H7GA 4U2MA 1FS1B 5BXHA 3MKSA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4JTA B;  2P1N A;  4JTD B;  2ASS A;  2VPK A;  3C6O A;  4N9F 5;  5IBK A;  2E31 B;  3OGL A;  2C9W C;  2OVQ A;  3LUT B;  1HV2 A;  3ZTC B;  4CRH A;  4CXJ A;  4U2N A;  2P1Q A;  4W9H H;  3HU6 A;  1DSX A;  5HZG C;  5A15 A;  3C6N A;  5BXD A;  3ZKJ B;  1P22 B;  3ZTD B;  1EOD A;  1EXB E;  3E4U A;  2PPI A;  3C6P A;  2NN2 A;  4WQO C;  2YY9 A;  3M4T A;  1EOE A;  3V7D A;  1R2B A;  2IF5 A;  2P1O A;  2OVP A;  4EOZ A;  4JTC B;  5EUP A;  4AWJ B;  1EOF A;  1FQV B;  3KVT A;  3WSO B;  4APF A;  2IHC A;  3DRZ A;  3HVE A;  5A6R A;  1T1D A;  3M8V A;  3B84 A;  4W9L B;  1S1G A;  4J8Z A;  2OVR A;  4W9K B;  4AJY C;  2P1P A;  3OHU A;  4HXI A;  1QDV A;  1NEX A;  3FKC A;  4U77 A;  4BKT B;  5DAF A;  4CXI A;  3M5B A;  4W9F B;  4CXT A;  4I6J C;  5H7H A;  3I3N A;  1NN7 A;  1VCB B;  5JH5 B;  3HQI A;  2JZ3 C;  2A79 B;  1FS2 B;  4W9D B;  2R9R B;  4W9E B;  3LNM B;  3BIM A;  3ZUN B;  4BGC A;  2Q81 A;  4JGH C;  2VKP A;  4UYI A;  3OGK A;  3M52 A;  2IZV C;  4W9H B;  4W9C B;  3L2O A;  1A68 A;  5HYW B;  4W9J B;  4BKS B;  2E32 B;  4W9G B;  1QDW A;  5BO4 C;  2MA9 C;  4B9K E;  1CS3 A;  4B95 B;  1R28 A;  1BUO A;  4CP3 A;  2FNJ C;  4UIJ A;  4ZOU A;  1LM8 C;  2Z8H A;  5FTA A;  3LBZ A;  1LQB B;  4B9K B;  3OGM A;  4AP2 A;  3ZNG B;  3HVE B;  5LLI B;  3OHV A;  3ZRC B;  5DAD A;  1LDK D;  2AST A;  2I2R A;  2NZ0 B;  3DCG B;  3GA1 A;  4W9I B;  3ZRF B;  1R29 A;  5BXB A;  3HTM A;  2P1M A;  5H7G A;  4U2M A;  1FS1 B;  5BXH A;  3MKS A; 
#chains in the Genus database with same CATH topology
 4JTA B;  2P1N A;  4JTD B;  2ASS A;  2VPK A;  3C6O A;  4N9F 5;  5IBK A;  2E31 B;  3OGL A;  2C9W C;  2OVQ A;  3LUT B;  1HV2 A;  3ZTC B;  4CRH A;  4CXJ A;  4U2N A;  2P1Q A;  4W9H H;  3HU6 A;  1DSX A;  5HZG C;  5A15 A;  3C6N A;  5BXD A;  3ZKJ B;  1P22 B;  3ZTD B;  1EOD A;  1EXB E;  3E4U A;  2PPI A;  3C6P A;  2NN2 A;  4WQO C;  2YY9 A;  3M4T A;  1EOE A;  3V7D A;  1R2B A;  2IF5 A;  2P1O A;  2OVP A;  4EOZ A;  4JTC B;  5EUP A;  4AWJ B;  1EOF A;  1FQV B;  3KVT A;  3WSO B;  4APF A;  2IHC A;  3DRZ A;  3HVE A;  5A6R A;  4YY8 A;  1T1D A;  3M8V A;  3B84 A;  4W9L B;  1S1G A;  4J8Z A;  4ZGC A;  2OVR A;  4W9K B;  4AJY C;  2P1P A;  3OHU A;  4HXI A;  1QDV A;  1NEX A;  3FKC A;  4U77 A;  4BKT B;  5DAF A;  4CXI A;  3M5B A;  4W9F B;  4CXT A;  4I6J C;  5H7H A;  3I3N A;  1NN7 A;  1VCB B;  5JH5 B;  3HQI A;  2JZ3 C;  2A79 B;  1FS2 B;  4W9D B;  2R9R B;  4W9E B;  3LNM B;  3BIM A;  3ZUN B;  3DRY A;  4BGC A;  2Q81 A;  4JGH C;  2VKP A;  4UYI A;  3OGK A;  3M52 A;  2IZV C;  4W9H B;  4W9C B;  3L2O A;  1A68 A;  5HYW B;  4W9J B;  4BKS B;  2E32 B;  4W9G B;  1QDW A;  5BO4 C;  2MA9 C;  4B9K E;  1CS3 A;  4B95 B;  1R28 A;  1BUO A;  4CP3 A;  2FNJ C;  4UIJ A;  4ZOU A;  1LM8 C;  2Z8H A;  5FTA A;  3LBZ A;  1LQB B;  4B9K B;  3OGM A;  4AP2 A;  3ZNG B;  3HVE B;  5LLI B;  3OHV A;  3ZRC B;  5DAD A;  1LDK D;  2AST A;  2I2R A;  2NZ0 B;  3DCG B;  3GA1 A;  4W9I B;  3ZRF B;  1R29 A;  5BXB A;  3DRX A;  3HTM A;  2P1M A;  5H7G A;  4U2M A;  1FS1 B;  5BXH A;  3MKS A; 
#chains in the Genus database with same CATH homology
 4JTA B;  2P1N A;  4JTD B;  2ASS A;  2VPK A;  3C6O A;  4N9F 5;  5IBK A;  2E31 B;  3OGL A;  2C9W C;  2OVQ A;  3LUT B;  1HV2 A;  3ZTC B;  4CRH A;  4CXJ A;  4U2N A;  2P1Q A;  4W9H H;  3HU6 A;  1DSX A;  5HZG C;  5A15 A;  3C6N A;  5BXD A;  3ZKJ B;  1P22 B;  3ZTD B;  1EOD A;  1EXB E;  3E4U A;  2PPI A;  3C6P A;  2NN2 A;  4WQO C;  2YY9 A;  3M4T A;  1EOE A;  3V7D A;  1R2B A;  2IF5 A;  2P1O A;  2OVP A;  4EOZ A;  4JTC B;  5EUP A;  4AWJ B;  1EOF A;  1FQV B;  3KVT A;  3WSO B;  4APF A;  2IHC A;  3DRZ A;  3HVE A;  5A6R A;  4YY8 A;  1T1D A;  3M8V A;  3B84 A;  4W9L B;  1S1G A;  4J8Z A;  4ZGC A;  2OVR A;  4W9K B;  4AJY C;  2P1P A;  3OHU A;  4HXI A;  1QDV A;  1NEX A;  3FKC A;  4U77 A;  4BKT B;  5DAF A;  4CXI A;  3M5B A;  4W9F B;  4CXT A;  4I6J C;  5H7H A;  3I3N A;  1NN7 A;  1VCB B;  5JH5 B;  3HQI A;  2JZ3 C;  2A79 B;  1FS2 B;  4W9D B;  2R9R B;  4W9E B;  3LNM B;  3BIM A;  3ZUN B;  3DRY A;  4BGC A;  2Q81 A;  4JGH C;  2VKP A;  4UYI A;  3OGK A;  3M52 A;  2IZV C;  4W9H B;  4W9C B;  3L2O A;  1A68 A;  5HYW B;  4W9J B;  4BKS B;  2E32 B;  4W9G B;  1QDW A;  5BO4 C;  2MA9 C;  4B9K E;  1CS3 A;  4B95 B;  1R28 A;  1BUO A;  4CP3 A;  2FNJ C;  4UIJ A;  4ZOU A;  1LM8 C;  2Z8H A;  5FTA A;  3LBZ A;  1LQB B;  4B9K B;  3OGM A;  4AP2 A;  3ZNG B;  3HVE B;  5LLI B;  3OHV A;  3ZRC B;  5DAD A;  1LDK D;  2AST A;  2I2R A;  2NZ0 B;  3DCG B;  3GA1 A;  4W9I B;  3ZRF B;  1R29 A;  5BXB A;  3DRX A;  3HTM A;  2P1M A;  5H7G A;  4U2M A;  1FS1 B;  5BXH A;  3MKS A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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