2UZQA

Protein phosphatase, new crystal form
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
171
structure length
171
Chain Sequence
GILELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title New Crystal Form of Protein Phosphatase Cdc25B Triggered by Guanidinium Chloride as an Additive
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords M-PHASE INDUCER PHOSPHATASE 2
total genus 57
structure length 171
sequence length 171
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2007-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00581 Rhodanese Rhodanese-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.250.10 Alpha Beta 3-Layer(aba) Sandwich Oxidized Rhodanese; domain 1 Rhodanese-like domain 2uzqA00
3I3UA 3IWHA 2JTQA 4F67A 2DCQA 4WH9A 3HWIA 5HBPA 2OUCA 4WH7A 3AAXA 4JGTA 3TG1B 2JTRA 2JTSA 2EG4A 2WLXA 1H4MX 3D1PA 3F4AA 1GMXA 1RHSA 3ICSA 1HZMA 1BOIA 5LAOA 2EG3A 3ILMA 2HHGA 1T3KA 1BOHA 1QB0A 5HPAA 3UTNX 4OCGA 1CWSA 3ICTA 1WV9A 3NT6A 2K0ZA 3K9RA 2GWFA 1QXNA 3IPOA 2FSXA 1GN0A 2UZQA 1DP2A 1RHDA 2MOLA 3HIXA 2WLRA 3TP9A 3MZZA 1CWRA 1ORBA 3FLHA 1WHBA 1OKGA 1YMDA 3NTDA 1YM9A 3IPPA 1H4KX 5LAMA 2IFDA 3G5JA 5HBQA 1E0CA 1VEEA 2A2KA 3NHVA 1YMKA 3FOJA 2J6PA 2MOIA 3FS5A 3P3AA 5HBOA 3ICRA 3I2VA 5HBLA 2MRMA 3O3WA 1UARA 3TG3A 2VSWA 1CWTA 1YMLA 1YT8A 1C25A 3HZUA 3FNJA 2ORAA 3OLHA 2IFVA 3NTAA 3OP3A 3GK5A 1YS0A 2EG4B 1URHA 2KL3A 1TQ1A 3AAYA 3R2UA
chains in the Genus database with same CATH superfamily
3I3UA 3IWHA 2JTQA 4F67A 2DCQA 4WH9A 3HWIA 5HBPA 2OUCA 4WH7A 3AAXA 4JGTA 3TG1B 2JTRA 2JTSA 2EG4A 2WLXA 1H4MX 3D1PA 3F4AA 1GMXA 1RHSA 3ICSA 1HZMA 1BOIA 5LAOA 2EG3A 3ILMA 2HHGA 1T3KA 1BOHA 1QB0A 5HPAA 3UTNX 4OCGA 1CWSA 3ICTA 1WV9A 3NT6A 2K0ZA 3K9RA 2GWFA 1QXNA 2Q82A 3IPOA 2FSXA 1GN0A 2UZQA 1DP2A 1RHDA 2MOLA 3HIXA 2WLRA 3TP9A 3MZZA 1CWRA 1ORBA 3FLHA 1WHBA 1OKGA 1YMDA 3NTDA 1YM9A 3IPPA 1H4KX 5LAMA 2IFDA 3G5JA 5HBQA 1E0CA 1VEEA 2A2KA 3NHVA 1YMKA 3FOJA 2J6PA 2MOIA 3FS5A 3P3AA 5HBOA 3ICRA 3I2VA 5HBLA 2MRMA 3O3WA 1UARA 3TG3A 2VSWA 1CWTA 1YMLA 1YT8A 1C25A 3HZUA 3FNJA 2ORAA 3OLHA 2IFVA 3NTAA 3OP3A 3GK5A 1YS0A 2EG4B 1URHA 2KL3A 1TQ1A 3AAYA 3R2UA
chains in the Genus database with same CATH topology
3I3UA 3IWHA 2JTQA 4F67A 2DCQA 4WH9A 3HWIA 5HBPA 2OUCA 4WH7A 3AAXA 4JGTA 3TG1B 2JTRA 2JTSA 2EG4A 2WLXA 1H4MX 3D1PA 3F4AA 1GMXA 1RHSA 3ICSA 1HZMA 1BOIA 5LAOA 2EG3A 3ILMA 2HHGA 1T3KA 1BOHA 1QB0A 5HPAA 3UTNX 4OCGA 1CWSA 3ICTA 1WV9A 3NT6A 2K0ZA 3K9RA 2GWFA 1QXNA 3IPOA 2FSXA 1GN0A 2UZQA 1DP2A 1RHDA 2MOLA 3HIXA 2WLRA 3TP9A 3MZZA 1CWRA 1ORBA 3FLHA 1WHBA 1OKGA 1YMDA 3NTDA 1YM9A 3IPPA 1H4KX 5LAMA 2IFDA 3G5JA 5HBQA 1E0CA 1VEEA 2A2KA 3NHVA 1YMKA 3FOJA 2J6PA 2MOIA 3FS5A 3P3AA 5HBOA 3ICRA 3I2VA 5HBLA 2MRMA 3O3WA 1UARA 3TG3A 2VSWA 1CWTA 1YMLA 1YT8A 1C25A 3HZUA 3FNJA 2ORAA 3OLHA 2IFVA 3NTAA 3OP3A 3GK5A 1YS0A 2EG4B 1URHA 2KL3A 1TQ1A 3AAYA 3R2UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I3U A;  3IWH A;  2JTQ A;  4F67 A;  2DCQ A;  4WH9 A;  3HWI A;  5HBP A;  2OUC A;  4WH7 A;  3AAX A;  4JGT A;  3TG1 B;  2JTR A;  2JTS A;  2EG4 A;  2WLX A;  1H4M X;  3D1P A;  3F4A A;  1GMX A;  1RHS A;  3ICS A;  1HZM A;  1BOI A;  5LAO A;  2EG3 A;  3ILM A;  2HHG A;  1T3K A;  1BOH A;  1QB0 A;  5HPA A;  3UTN X;  4OCG A;  1CWS A;  3ICT A;  1WV9 A;  3NT6 A;  2K0Z A;  3K9R A;  2GWF A;  1QXN A;  3IPO A;  2FSX A;  1GN0 A;  2UZQ A;  1DP2 A;  1RHD A;  2MOL A;  3HIX A;  2WLR A;  3TP9 A;  3MZZ A;  1CWR A;  1ORB A;  3FLH A;  1WHB A;  1OKG A;  1YMD A;  3NTD A;  1YM9 A;  3IPP A;  1H4K X;  5LAM A;  2IFD A;  3G5J A;  5HBQ A;  1E0C A;  1VEE A;  2A2K A;  3NHV A;  1YMK A;  3FOJ A;  2J6P A;  2MOI A;  3FS5 A;  3P3A A;  5HBO A;  3ICR A;  3I2V A;  5HBL A;  2MRM A;  3O3W A;  1UAR A;  3TG3 A;  2VSW A;  1CWT A;  1YML A;  1YT8 A;  1C25 A;  3HZU A;  3FNJ A;  2ORA A;  3OLH A;  2IFV A;  3NTA A;  3OP3 A;  3GK5 A;  1YS0 A;  2EG4 B;  1URH A;  2KL3 A;  1TQ1 A;  3AAY A;  3R2U A; 
#chains in the Genus database with same CATH topology
 3I3U A;  3IWH A;  2JTQ A;  4F67 A;  2DCQ A;  4WH9 A;  3HWI A;  5HBP A;  2OUC A;  4WH7 A;  3AAX A;  4JGT A;  3TG1 B;  2JTR A;  2JTS A;  2EG4 A;  2WLX A;  1H4M X;  3D1P A;  3F4A A;  1GMX A;  1RHS A;  3ICS A;  1HZM A;  1BOI A;  5LAO A;  2EG3 A;  3ILM A;  2HHG A;  1T3K A;  1BOH A;  1QB0 A;  5HPA A;  3UTN X;  4OCG A;  1CWS A;  3ICT A;  1WV9 A;  3NT6 A;  2K0Z A;  3K9R A;  2GWF A;  1QXN A;  2Q82 A;  3IPO A;  2FSX A;  1GN0 A;  2UZQ A;  1DP2 A;  1RHD A;  2MOL A;  3HIX A;  2WLR A;  3TP9 A;  3MZZ A;  1CWR A;  1ORB A;  3FLH A;  1WHB A;  1OKG A;  1YMD A;  3NTD A;  1YM9 A;  3IPP A;  1H4K X;  5LAM A;  2IFD A;  3G5J A;  5HBQ A;  1E0C A;  1VEE A;  2A2K A;  3NHV A;  1YMK A;  3FOJ A;  2J6P A;  2MOI A;  3FS5 A;  3P3A A;  5HBO A;  3ICR A;  3I2V A;  5HBL A;  2MRM A;  3O3W A;  1UAR A;  3TG3 A;  2VSW A;  1CWT A;  1YML A;  1YT8 A;  1C25 A;  3HZU A;  3FNJ A;  2ORA A;  3OLH A;  2IFV A;  3NTA A;  3OP3 A;  3GK5 A;  1YS0 A;  2EG4 B;  1URH A;  2KL3 A;  1TQ1 A;  3AAY A;  3R2U A; 
#chains in the Genus database with same CATH homology
 3I3U A;  3IWH A;  2JTQ A;  4F67 A;  2DCQ A;  4WH9 A;  3HWI A;  5HBP A;  2OUC A;  4WH7 A;  3AAX A;  4JGT A;  3TG1 B;  2JTR A;  2JTS A;  2EG4 A;  2WLX A;  1H4M X;  3D1P A;  3F4A A;  1GMX A;  1RHS A;  3ICS A;  1HZM A;  1BOI A;  5LAO A;  2EG3 A;  3ILM A;  2HHG A;  1T3K A;  1BOH A;  1QB0 A;  5HPA A;  3UTN X;  4OCG A;  1CWS A;  3ICT A;  1WV9 A;  3NT6 A;  2K0Z A;  3K9R A;  2GWF A;  1QXN A;  3IPO A;  2FSX A;  1GN0 A;  2UZQ A;  1DP2 A;  1RHD A;  2MOL A;  3HIX A;  2WLR A;  3TP9 A;  3MZZ A;  1CWR A;  1ORB A;  3FLH A;  1WHB A;  1OKG A;  1YMD A;  3NTD A;  1YM9 A;  3IPP A;  1H4K X;  5LAM A;  2IFD A;  3G5J A;  5HBQ A;  1E0C A;  1VEE A;  2A2K A;  3NHV A;  1YMK A;  3FOJ A;  2J6P A;  2MOI A;  3FS5 A;  3P3A A;  5HBO A;  3ICR A;  3I2V A;  5HBL A;  2MRM A;  3O3W A;  1UAR A;  3TG3 A;  2VSW A;  1CWT A;  1YML A;  1YT8 A;  1C25 A;  3HZU A;  3FNJ A;  2ORA A;  3OLH A;  2IFV A;  3NTA A;  3OP3 A;  3GK5 A;  1YS0 A;  2EG4 B;  1URH A;  2KL3 A;  1TQ1 A;  3AAY A;  3R2U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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