3GH2X

Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
Knots found
sequence length
304
structure length
275
Chain Sequence
ELPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
pubmed doi rcsb
molecule keywords Thymidylate synthase
total genus 81
structure length 275
sequence length 304
other databases KnotProt 2.0: Artifct K +31
ec nomenclature ec 2.1.1.45: Thymidylate synthase.
pdb deposition date 2009-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00303 Thymidylat_synt Thymidylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase; Chain A Thymidylate synthase/dCMP hydroxymethylase domain 3gh2X00
4O1XA 1JUJA 3BHLA 4H0RA 4JEFA 1TLSA 1KZIA 3IX6A 4FOXA 3IHIA 1QQQA 1RTSA 1YPVA 3IROA 1F28A 1EVFA 3KJRA 1B5DA 1BIDA 1JTUA 4KPWA 1TVVA 1SYNA 3BYXA 3QJ7A 1JMGA 1BJGA 4KY4A 4E28A 3EF9A 3C0AA 4KYAA 4EZ8A 4EINA 1AXWA 3IK0A 4KNZA 2FTNA 3HJ3A 1EV5A 1TDBA 3TMSA 4IRRA 1KCEA 3GH0A 3UWLB 2G89A 2VF0A 4KY8A 1B49A 3EBUA 4H0UA 3UWLA 1AN5A 1BP6A 1J3JC 1SEJA 1TRGA 1JTQA 1AJMA 2FTOX 3BFIA 1DNAA 3UM6A 1DDUA 1TSNA 4GYHA 2OIPA 1BKPA 4ISKA 3DG8C 1ZPRA 3BHRA 5FCTA 1NJAA 3H9KA 4XSCA 1KZJA 1JU6A 1TSWA 4O1XD 4XSDA 1LCBA 1BSFA 3I3RA 1J3KC 3KJSA 1F4EA 1TVWA 3BNZA 4G6WX 1BO7A 5H38A 4DPHA 1BKOA 2TDMA 3C06A 3IJZA 1F4DA 1TSYA 4IQBA 4LRRA 1J3IC 4ECKA 4FOGA 4FOAA 1TSXA 1JMIA 2G8DA 1HZWA 1TVUA 1BQ1A 3CLBA 1F4GA 1BO8A 2A9WA 1F4CA 1F4FA 3EAWX 3GH2X 2ONBA 3UM8A 4PSGA 4XSEA 3UM5A 4DQ1A 3BZ0A 1FFLA 1JMHA 3HBBA 3K2HA 3QG2A 3GG5A 2H2QA 3NRRA 3EJLA 4E5OA 2TSCA 1TDCA 1VZAA 3DGAC 4O1UA 5H39A 4DP3A 2RDAA 2TSRA 1CI7A 1I00A 1NJEA 3EDWX 1JMFA 1TDAA 3EGYX 4TMSA 3KGBA 1THYA 3B5BA 2FTQA 1LCEA 3QGTA 1NJCA 5WRNA 4FGTA 2RD8B 5J7WA 1EVGA 3HB8A 1TSVA 1QZFA 4DPDA 1BP0A 1VZBA 1TSMA 2KCEA 5BY6A 2G86A 3EHIX 1JUTA 1TYSA 3ED7A 4IQQA 1VZDA 4G2OX 3N5GA 1NJBA 2VETA 1TSZA 3JSUA 1TISA 1TSLA 4Q0DA 3V8HA 1AIQA 4UP1A 4ISWA 1TJSA 3CL9A 1BSPA 2BBQA 2G8XA 3N5EB 1JG0A 3OB7A 3N5EA 1HW3A 3IRNA 3B9HA 4EB4A 1BPJA 2TDDA 1TDUA 4EILA 4H1IA 1F4BA 2G8AA 1B5EA 1BQ2A 1LCAA 1VZCA 3DL6A 4O7UA 4F2VA 2AAZA 5H3AA 3BGXA 1NCEA 4Q0EA 1AOBA 1B02A 1HVYA 1FWMA 1NJDA 5HS3A 3DL5A 1HW4A 1VZEA 3INVA 1TLCA 3IK1A 3IRMA 4FQSA 4GEVA 1TSDA 2RD8A 1EV8A 1BDUA 4GD7A
chains in the Genus database with same CATH superfamily
4O1XA 1JUJA 3BHLA 4H0RA 4JEFA 1TLSA 1KZIA 3IX6A 4FOXA 3IHIA 1QQQA 1RTSA 1YPVA 3IROA 1F28A 1EVFA 3KJRA 1B5DA 1BIDA 1JTUA 4KPWA 1TVVA 1SYNA 3BYXA 3QJ7A 1JMGA 1BJGA 4KY4A 4E28A 3EF9A 3C0AA 4KYAA 4EZ8A 4EINA 1AXWA 3IK0A 4KNZA 2FTNA 3HJ3A 1EV5A 1TDBA 3TMSA 4IRRA 1KCEA 3GH0A 3UWLB 2G89A 2VF0A 4KY8A 1B49A 3EBUA 4H0UA 3UWLA 1AN5A 1BP6A 1J3JC 1SEJA 1TRGA 1JTQA 1AJMA 2FTOX 3BFIA 1DNAA 3UM6A 1DDUA 1TSNA 4GYHA 2OIPA 1BKPA 4ISKA 3DG8C 1ZPRA 3BHRA 5FCTA 1NJAA 3H9KA 4XSCA 1KZJA 1JU6A 1TSWA 4O1XD 4XSDA 1LCBA 1BSFA 3I3RA 1J3KC 3KJSA 1F4EA 1TVWA 3BNZA 4G6WX 1BO7A 5H38A 4DPHA 1BKOA 2TDMA 3C06A 3IJZA 1F4DA 1TSYA 4IQBA 4LRRA 1J3IC 4ECKA 4FOGA 4FOAA 1TSXA 1JMIA 2G8DA 1HZWA 1TVUA 1BQ1A 3CLBA 1F4GA 1BO8A 2A9WA 1F4CA 1F4FA 3EAWX 3GH2X 2ONBA 3UM8A 4PSGA 4XSEA 3UM5A 4DQ1A 3BZ0A 1FFLA 1JMHA 3HBBA 3K2HA 3QG2A 3GG5A 2H2QA 3NRRA 3EJLA 4E5OA 2TSCA 1TDCA 1VZAA 3DGAC 4O1UA 5H39A 4DP3A 2RDAA 2TSRA 1CI7A 1I00A 1NJEA 3EDWX 1JMFA 1TDAA 3EGYX 4TMSA 3KGBA 1THYA 3B5BA 2FTQA 1LCEA 3QGTA 1NJCA 5WRNA 4FGTA 2RD8B 5J7WA 1EVGA 3HB8A 1TSVA 1QZFA 4DPDA 1BP0A 1VZBA 1TSMA 2KCEA 5BY6A 2G86A 3EHIX 1JUTA 1TYSA 3ED7A 4IQQA 1VZDA 4G2OX 3N5GA 1NJBA 2VETA 1TSZA 3JSUA 1TISA 1TSLA 4Q0DA 3V8HA 1AIQA 4UP1A 4ISWA 1TJSA 3CL9A 1BSPA 2BBQA 2G8XA 3N5EB 1JG0A 3OB7A 3N5EA 1HW3A 3IRNA 3B9HA 4EB4A 1BPJA 2TDDA 1TDUA 4EILA 4H1IA 1F4BA 2G8AA 1B5EA 1BQ2A 1LCAA 1VZCA 3DL6A 4O7UA 4F2VA 2AAZA 5H3AA 3BGXA 1NCEA 4Q0EA 1AOBA 1B02A 1HVYA 1FWMA 1NJDA 5HS3A 3DL5A 1HW4A 1VZEA 3INVA 1TLCA 3IK1A 3IRMA 4FQSA 4GEVA 1TSDA 2RD8A 1EV8A 1BDUA 4GD7A
chains in the Genus database with same CATH topology
4O1XA 1JUJA 3BHLA 4H0RA 4JEFA 1TLSA 1KZIA 3IX6A 4FOXA 3IHIA 1QQQA 1RTSA 1YPVA 3IROA 1F28A 1EVFA 3KJRA 1B5DA 1BIDA 1JTUA 4KPWA 1TVVA 1SYNA 3BYXA 3QJ7A 1JMGA 1BJGA 4KY4A 4E28A 3EF9A 3C0AA 4KYAA 4EZ8A 4EINA 1AXWA 3IK0A 4KNZA 2FTNA 3HJ3A 1EV5A 1TDBA 3TMSA 4IRRA 1KCEA 3GH0A 3UWLB 2G89A 2VF0A 4KY8A 1B49A 3EBUA 4H0UA 3UWLA 1AN5A 1BP6A 1J3JC 1SEJA 1TRGA 1JTQA 1AJMA 2FTOX 3BFIA 1DNAA 3UM6A 1DDUA 1TSNA 4GYHA 2OIPA 1BKPA 4ISKA 3DG8C 1ZPRA 3BHRA 5FCTA 1NJAA 3H9KA 4XSCA 1KZJA 1JU6A 1TSWA 4O1XD 4XSDA 1LCBA 1BSFA 3I3RA 1J3KC 3KJSA 1F4EA 1TVWA 3BNZA 4G6WX 1BO7A 5H38A 4DPHA 1BKOA 2TDMA 3C06A 3IJZA 1F4DA 1TSYA 4IQBA 4LRRA 1J3IC 4ECKA 4FOGA 4FOAA 1TSXA 1JMIA 2G8DA 1HZWA 1TVUA 1BQ1A 3CLBA 1F4GA 1BO8A 2A9WA 1F4CA 1F4FA 3EAWX 3GH2X 2ONBA 3UM8A 4PSGA 4XSEA 3UM5A 4DQ1A 3BZ0A 1FFLA 1JMHA 3HBBA 3K2HA 3QG2A 3GG5A 2H2QA 3NRRA 3EJLA 4E5OA 2TSCA 1TDCA 1VZAA 3DGAC 4O1UA 5H39A 4DP3A 2RDAA 2TSRA 1CI7A 1I00A 1NJEA 3EDWX 1JMFA 1TDAA 3EGYX 4TMSA 3KGBA 1THYA 3B5BA 2FTQA 1LCEA 3QGTA 1NJCA 5WRNA 4FGTA 2RD8B 5J7WA 1EVGA 3HB8A 1TSVA 1QZFA 4DPDA 1BP0A 1VZBA 1TSMA 2KCEA 5BY6A 2G86A 3EHIX 1JUTA 1TYSA 3ED7A 4IQQA 1VZDA 4G2OX 3N5GA 1NJBA 2VETA 1TSZA 3JSUA 1TISA 1TSLA 4Q0DA 3V8HA 1AIQA 4UP1A 4ISWA 1TJSA 3CL9A 1BSPA 2BBQA 2G8XA 3N5EB 1JG0A 3OB7A 3N5EA 1HW3A 3IRNA 3B9HA 4EB4A 1BPJA 2TDDA 1TDUA 4EILA 4H1IA 1F4BA 2G8AA 1B5EA 1BQ2A 1LCAA 1VZCA 3DL6A 4O7UA 4F2VA 2AAZA 5H3AA 3BGXA 1NCEA 4Q0EA 1AOBA 1B02A 1HVYA 1FWMA 1NJDA 5HS3A 3DL5A 1HW4A 1VZEA 3INVA 1TLCA 3IK1A 3IRMA 4FQSA 4GEVA 1TSDA 2RD8A 1EV8A 1BDUA 4GD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O1X A;  1JUJ A;  3BHL A;  4H0R A;  4JEF A;  1TLS A;  1KZI A;  3IX6 A;  4FOX A;  3IHI A;  1QQQ A;  1RTS A;  1YPV A;  3IRO A;  1F28 A;  1EVF A;  3KJR A;  1B5D A;  1BID A;  1JTU A;  4KPW A;  1TVV A;  1SYN A;  3BYX A;  3QJ7 A;  1JMG A;  1BJG A;  4KY4 A;  4E28 A;  3EF9 A;  3C0A A;  4KYA A;  4EZ8 A;  4EIN A;  1AXW A;  3IK0 A;  4KNZ A;  2FTN A;  3HJ3 A;  1EV5 A;  1TDB A;  3TMS A;  4IRR A;  1KCE A;  3GH0 A;  3UWL B;  2G89 A;  2VF0 A;  4KY8 A;  1B49 A;  3EBU A;  4H0U A;  3UWL A;  1AN5 A;  1BP6 A;  1J3J C;  1SEJ A;  1TRG A;  1JTQ A;  1AJM A;  2FTO X;  3BFI A;  1DNA A;  3UM6 A;  1DDU A;  1TSN A;  4GYH A;  2OIP A;  1BKP A;  4ISK A;  3DG8 C;  1ZPR A;  3BHR A;  5FCT A;  1NJA A;  3H9K A;  4XSC A;  1KZJ A;  1JU6 A;  1TSW A;  4O1X D;  4XSD A;  1LCB A;  1BSF A;  3I3R A;  1J3K C;  3KJS A;  1F4E A;  1TVW A;  3BNZ A;  4G6W X;  1BO7 A;  5H38 A;  4DPH A;  1BKO A;  2TDM A;  3C06 A;  3IJZ A;  1F4D A;  1TSY A;  4IQB A;  4LRR A;  1J3I C;  4ECK A;  4FOG A;  4FOA A;  1TSX A;  1JMI A;  2G8D A;  1HZW A;  1TVU A;  1BQ1 A;  3CLB A;  1F4G A;  1BO8 A;  2A9W A;  1F4C A;  1F4F A;  3EAW X;  3GH2 X;  2ONB A;  3UM8 A;  4PSG A;  4XSE A;  3UM5 A;  4DQ1 A;  3BZ0 A;  1FFL A;  1JMH A;  3HBB A;  3K2H A;  3QG2 A;  3GG5 A;  2H2Q A;  3NRR A;  3EJL A;  4E5O A;  2TSC A;  1TDC A;  1VZA A;  3DGA C;  4O1U A;  5H39 A;  4DP3 A;  2RDA A;  2TSR A;  1CI7 A;  1I00 A;  1NJE A;  3EDW X;  1JMF A;  1TDA A;  3EGY X;  4TMS A;  3KGB A;  1THY A;  3B5B A;  2FTQ A;  1LCE A;  3QGT A;  1NJC A;  5WRN A;  4FGT A;  2RD8 B;  5J7W A;  1EVG A;  3HB8 A;  1TSV A;  1QZF A;  4DPD A;  1BP0 A;  1VZB A;  1TSM A;  2KCE A;  5BY6 A;  2G86 A;  3EHI X;  1JUT A;  1TYS A;  3ED7 A;  4IQQ A;  1VZD A;  4G2O X;  3N5G A;  1NJB A;  2VET A;  1TSZ A;  3JSU A;  1TIS A;  1TSL A;  4Q0D A;  3V8H A;  1AIQ A;  4UP1 A;  4ISW A;  1TJS A;  3CL9 A;  1BSP A;  2BBQ A;  2G8X A;  3N5E B;  1JG0 A;  3OB7 A;  3N5E A;  1HW3 A;  3IRN A;  3B9H A;  4EB4 A;  1BPJ A;  2TDD A;  1TDU A;  4EIL A;  4H1I A;  1F4B A;  2G8A A;  1B5E A;  1BQ2 A;  1LCA A;  1VZC A;  3DL6 A;  4O7U A;  4F2V A;  2AAZ A;  5H3A A;  3BGX A;  1NCE A;  4Q0E A;  1AOB A;  1B02 A;  1HVY A;  1FWM A;  1NJD A;  5HS3 A;  3DL5 A;  1HW4 A;  1VZE A;  3INV A;  1TLC A;  3IK1 A;  3IRM A;  4FQS A;  4GEV A;  1TSD A;  2RD8 A;  1EV8 A;  1BDU A;  4GD7 A; 
#chains in the Genus database with same CATH topology
 4O1X A;  1JUJ A;  3BHL A;  4H0R A;  4JEF A;  1TLS A;  1KZI A;  3IX6 A;  4FOX A;  3IHI A;  1QQQ A;  1RTS A;  1YPV A;  3IRO A;  1F28 A;  1EVF A;  3KJR A;  1B5D A;  1BID A;  1JTU A;  4KPW A;  1TVV A;  1SYN A;  3BYX A;  3QJ7 A;  1JMG A;  1BJG A;  4KY4 A;  4E28 A;  3EF9 A;  3C0A A;  4KYA A;  4EZ8 A;  4EIN A;  1AXW A;  3IK0 A;  4KNZ A;  2FTN A;  3HJ3 A;  1EV5 A;  1TDB A;  3TMS A;  4IRR A;  1KCE A;  3GH0 A;  3UWL B;  2G89 A;  2VF0 A;  4KY8 A;  1B49 A;  3EBU A;  4H0U A;  3UWL A;  1AN5 A;  1BP6 A;  1J3J C;  1SEJ A;  1TRG A;  1JTQ A;  1AJM A;  2FTO X;  3BFI A;  1DNA A;  3UM6 A;  1DDU A;  1TSN A;  4GYH A;  2OIP A;  1BKP A;  4ISK A;  3DG8 C;  1ZPR A;  3BHR A;  5FCT A;  1NJA A;  3H9K A;  4XSC A;  1KZJ A;  1JU6 A;  1TSW A;  4O1X D;  4XSD A;  1LCB A;  1BSF A;  3I3R A;  1J3K C;  3KJS A;  1F4E A;  1TVW A;  3BNZ A;  4G6W X;  1BO7 A;  5H38 A;  4DPH A;  1BKO A;  2TDM A;  3C06 A;  3IJZ A;  1F4D A;  1TSY A;  4IQB A;  4LRR A;  1J3I C;  4ECK A;  4FOG A;  4FOA A;  1TSX A;  1JMI A;  2G8D A;  1HZW A;  1TVU A;  1BQ1 A;  3CLB A;  1F4G A;  1BO8 A;  2A9W A;  1F4C A;  1F4F A;  3EAW X;  3GH2 X;  2ONB A;  3UM8 A;  4PSG A;  4XSE A;  3UM5 A;  4DQ1 A;  3BZ0 A;  1FFL A;  1JMH A;  3HBB A;  3K2H A;  3QG2 A;  3GG5 A;  2H2Q A;  3NRR A;  3EJL A;  4E5O A;  2TSC A;  1TDC A;  1VZA A;  3DGA C;  4O1U A;  5H39 A;  4DP3 A;  2RDA A;  2TSR A;  1CI7 A;  1I00 A;  1NJE A;  3EDW X;  1JMF A;  1TDA A;  3EGY X;  4TMS A;  3KGB A;  1THY A;  3B5B A;  2FTQ A;  1LCE A;  3QGT A;  1NJC A;  5WRN A;  4FGT A;  2RD8 B;  5J7W A;  1EVG A;  3HB8 A;  1TSV A;  1QZF A;  4DPD A;  1BP0 A;  1VZB A;  1TSM A;  2KCE A;  5BY6 A;  2G86 A;  3EHI X;  1JUT A;  1TYS A;  3ED7 A;  4IQQ A;  1VZD A;  4G2O X;  3N5G A;  1NJB A;  2VET A;  1TSZ A;  3JSU A;  1TIS A;  1TSL A;  4Q0D A;  3V8H A;  1AIQ A;  4UP1 A;  4ISW A;  1TJS A;  3CL9 A;  1BSP A;  2BBQ A;  2G8X A;  3N5E B;  1JG0 A;  3OB7 A;  3N5E A;  1HW3 A;  3IRN A;  3B9H A;  4EB4 A;  1BPJ A;  2TDD A;  1TDU A;  4EIL A;  4H1I A;  1F4B A;  2G8A A;  1B5E A;  1BQ2 A;  1LCA A;  1VZC A;  3DL6 A;  4O7U A;  4F2V A;  2AAZ A;  5H3A A;  3BGX A;  1NCE A;  4Q0E A;  1AOB A;  1B02 A;  1HVY A;  1FWM A;  1NJD A;  5HS3 A;  3DL5 A;  1HW4 A;  1VZE A;  3INV A;  1TLC A;  3IK1 A;  3IRM A;  4FQS A;  4GEV A;  1TSD A;  2RD8 A;  1EV8 A;  1BDU A;  4GD7 A; 
#chains in the Genus database with same CATH homology
 4O1X A;  1JUJ A;  3BHL A;  4H0R A;  4JEF A;  1TLS A;  1KZI A;  3IX6 A;  4FOX A;  3IHI A;  1QQQ A;  1RTS A;  1YPV A;  3IRO A;  1F28 A;  1EVF A;  3KJR A;  1B5D A;  1BID A;  1JTU A;  4KPW A;  1TVV A;  1SYN A;  3BYX A;  3QJ7 A;  1JMG A;  1BJG A;  4KY4 A;  4E28 A;  3EF9 A;  3C0A A;  4KYA A;  4EZ8 A;  4EIN A;  1AXW A;  3IK0 A;  4KNZ A;  2FTN A;  3HJ3 A;  1EV5 A;  1TDB A;  3TMS A;  4IRR A;  1KCE A;  3GH0 A;  3UWL B;  2G89 A;  2VF0 A;  4KY8 A;  1B49 A;  3EBU A;  4H0U A;  3UWL A;  1AN5 A;  1BP6 A;  1J3J C;  1SEJ A;  1TRG A;  1JTQ A;  1AJM A;  2FTO X;  3BFI A;  1DNA A;  3UM6 A;  1DDU A;  1TSN A;  4GYH A;  2OIP A;  1BKP A;  4ISK A;  3DG8 C;  1ZPR A;  3BHR A;  5FCT A;  1NJA A;  3H9K A;  4XSC A;  1KZJ A;  1JU6 A;  1TSW A;  4O1X D;  4XSD A;  1LCB A;  1BSF A;  3I3R A;  1J3K C;  3KJS A;  1F4E A;  1TVW A;  3BNZ A;  4G6W X;  1BO7 A;  5H38 A;  4DPH A;  1BKO A;  2TDM A;  3C06 A;  3IJZ A;  1F4D A;  1TSY A;  4IQB A;  4LRR A;  1J3I C;  4ECK A;  4FOG A;  4FOA A;  1TSX A;  1JMI A;  2G8D A;  1HZW A;  1TVU A;  1BQ1 A;  3CLB A;  1F4G A;  1BO8 A;  2A9W A;  1F4C A;  1F4F A;  3EAW X;  3GH2 X;  2ONB A;  3UM8 A;  4PSG A;  4XSE A;  3UM5 A;  4DQ1 A;  3BZ0 A;  1FFL A;  1JMH A;  3HBB A;  3K2H A;  3QG2 A;  3GG5 A;  2H2Q A;  3NRR A;  3EJL A;  4E5O A;  2TSC A;  1TDC A;  1VZA A;  3DGA C;  4O1U A;  5H39 A;  4DP3 A;  2RDA A;  2TSR A;  1CI7 A;  1I00 A;  1NJE A;  3EDW X;  1JMF A;  1TDA A;  3EGY X;  4TMS A;  3KGB A;  1THY A;  3B5B A;  2FTQ A;  1LCE A;  3QGT A;  1NJC A;  5WRN A;  4FGT A;  2RD8 B;  5J7W A;  1EVG A;  3HB8 A;  1TSV A;  1QZF A;  4DPD A;  1BP0 A;  1VZB A;  1TSM A;  2KCE A;  5BY6 A;  2G86 A;  3EHI X;  1JUT A;  1TYS A;  3ED7 A;  4IQQ A;  1VZD A;  4G2O X;  3N5G A;  1NJB A;  2VET A;  1TSZ A;  3JSU A;  1TIS A;  1TSL A;  4Q0D A;  3V8H A;  1AIQ A;  4UP1 A;  4ISW A;  1TJS A;  3CL9 A;  1BSP A;  2BBQ A;  2G8X A;  3N5E B;  1JG0 A;  3OB7 A;  3N5E A;  1HW3 A;  3IRN A;  3B9H A;  4EB4 A;  1BPJ A;  2TDD A;  1TDU A;  4EIL A;  4H1I A;  1F4B A;  2G8A A;  1B5E A;  1BQ2 A;  1LCA A;  1VZC A;  3DL6 A;  4O7U A;  4F2V A;  2AAZ A;  5H3A A;  3BGX A;  1NCE A;  4Q0E A;  1AOB A;  1B02 A;  1HVY A;  1FWM A;  1NJD A;  5HS3 A;  3DL5 A;  1HW4 A;  1VZE A;  3INV A;  1TLC A;  3IK1 A;  3IRM A;  4FQS A;  4GEV A;  1TSD A;  2RD8 A;  1EV8 A;  1BDU A;  4GD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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