3HWIA

Crystal structure of probable thiosulfate sulfurtransferase cysa2 (rhodanese-like protein) from mycobacterium tuberculosis
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
275
structure length
267
Chain Sequence
RCDVLVSADWAESNLHAPKVVFVEVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDEFSGKILAPQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCRIGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIELGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Mycobacterium tuberculosis
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule keywords Thiosulfate sulfurtransferase
total genus 95
structure length 267
sequence length 275
chains with identical sequence B
ec nomenclature ec 2.8.1.1: Thiosulfate sulfurtransferase.
pdb deposition date 2009-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00581 Rhodanese Rhodanese-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.250.10 Alpha Beta 3-Layer(aba) Sandwich Oxidized Rhodanese; domain 1 Rhodanese-like domain 3hwiA02
3.40.250.10 Alpha Beta 3-Layer(aba) Sandwich Oxidized Rhodanese; domain 1 Rhodanese-like domain 3hwiA01
2EG3A 3TG1B 1BOIA 4OCGA 2UZQA 3AAXA 5LAMA 1URHA 3K9RA 5HPAA 4WH9A 2WLRA 2WLXA 3GK5A 1T3KA 3NTAA 3FLHA 3ICSA 3FNJA 3G5JA 1RHDA 1CWTA 3R2UA 1C25A 2FSXA 2MOIA 3IPOA 1GMXA 2JTQA 3FOJA 5HBPA 3NHVA 1YS0A 1TQ1A 2K0ZA 3OLHA 1ORBA 3D1PA 1UARA 2MRMA 2OUCA 3NTDA 5HBOA 1WHBA 3FS5A 1H4KX 3HZUA 1CWRA 1OKGA 2HHGA 3HWIA 5HBQA 1HZMA 2ORAA 3MZZA 1YM9A 1RHSA 3AAYA 3UTNX 1VEEA 2MOLA 3IPPA 1YMLA 3NT6A 1YT8A 2IFVA 4F67A 3ICRA 3ILMA 5LAOA 1H4MX 1CWSA 1E0CA 2EG4B 2JTSA 2GWFA 2EG4A 3P3AA 2DCQA 3O3WA 4JGTA 1QB0A 1QXNA 3TP9A 3ICTA 5HBLA 2A2KA 2J6PA 2KL3A 1DP2A 1YMDA 3OP3A 3TG3A 2VSWA 1BOHA 1YMKA 3HIXA 3I3UA 1GN0A 4WH7A 3F4AA 3I2VA 2JTRA 1WV9A 2IFDA 3IWHA
chains in the Genus database with same CATH superfamily
2EG3A 3TG1B 1BOIA 4OCGA 2UZQA 3AAXA 5LAMA 1URHA 3K9RA 5HPAA 4WH9A 2WLRA 2WLXA 3GK5A 1T3KA 3NTAA 3FLHA 3ICSA 3FNJA 2Q82A 3G5JA 1RHDA 1CWTA 3R2UA 1C25A 2FSXA 2MOIA 3IPOA 1GMXA 2JTQA 3FOJA 5HBPA 3NHVA 1YS0A 1TQ1A 2K0ZA 3OLHA 1ORBA 3D1PA 1UARA 2MRMA 2OUCA 3NTDA 5HBOA 1WHBA 3FS5A 1H4KX 3HZUA 1CWRA 1OKGA 2HHGA 3HWIA 5HBQA 1HZMA 2ORAA 3MZZA 1YM9A 1RHSA 3AAYA 3UTNX 1VEEA 2MOLA 3IPPA 1YMLA 3NT6A 1YT8A 2IFVA 4F67A 3ICRA 3ILMA 5LAOA 1H4MX 1CWSA 1E0CA 2EG4B 2JTSA 2GWFA 2EG4A 3P3AA 2DCQA 3O3WA 4JGTA 1QB0A 1QXNA 3TP9A 3ICTA 5HBLA 2A2KA 2J6PA 2KL3A 1DP2A 1YMDA 3OP3A 3TG3A 2VSWA 1BOHA 1YMKA 3HIXA 3I3UA 1GN0A 4WH7A 3F4AA 3I2VA 2JTRA 1WV9A 2IFDA 3IWHA
chains in the Genus database with same CATH topology
2EG3A 3TG1B 1BOIA 4OCGA 2UZQA 3AAXA 5LAMA 1URHA 3K9RA 5HPAA 4WH9A 2WLRA 2WLXA 3GK5A 1T3KA 3NTAA 3FLHA 3ICSA 3FNJA 3G5JA 1RHDA 1CWTA 3R2UA 1C25A 2FSXA 2MOIA 3IPOA 1GMXA 2JTQA 3FOJA 5HBPA 3NHVA 1YS0A 1TQ1A 2K0ZA 3OLHA 1ORBA 3D1PA 1UARA 2MRMA 2OUCA 3NTDA 5HBOA 1WHBA 3FS5A 1H4KX 3HZUA 1CWRA 1OKGA 2HHGA 3HWIA 5HBQA 1HZMA 2ORAA 3MZZA 1YM9A 1RHSA 3AAYA 3UTNX 1VEEA 2MOLA 3IPPA 1YMLA 3NT6A 1YT8A 2IFVA 4F67A 3ICRA 3ILMA 5LAOA 1H4MX 1CWSA 1E0CA 2EG4B 2JTSA 2GWFA 2EG4A 3P3AA 2DCQA 3O3WA 4JGTA 1QB0A 1QXNA 3TP9A 3ICTA 5HBLA 2A2KA 2J6PA 2KL3A 1DP2A 1YMDA 3OP3A 3TG3A 2VSWA 1BOHA 1YMKA 3HIXA 3I3UA 1GN0A 4WH7A 3F4AA 3I2VA 2JTRA 1WV9A 2IFDA 3IWHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EG3 A;  3TG1 B;  1BOI A;  4OCG A;  2UZQ A;  3AAX A;  5LAM A;  1URH A;  3K9R A;  5HPA A;  4WH9 A;  2WLR A;  2WLX A;  3GK5 A;  1T3K A;  3NTA A;  3FLH A;  3ICS A;  3FNJ A;  3G5J A;  1RHD A;  1CWT A;  3R2U A;  1C25 A;  2FSX A;  2MOI A;  3IPO A;  1GMX A;  2JTQ A;  3FOJ A;  5HBP A;  3NHV A;  1YS0 A;  1TQ1 A;  2K0Z A;  3OLH A;  1ORB A;  3D1P A;  1UAR A;  2MRM A;  2OUC A;  3NTD A;  5HBO A;  1WHB A;  3FS5 A;  1H4K X;  3HZU A;  1CWR A;  1OKG A;  2HHG A;  3HWI A;  5HBQ A;  1HZM A;  2ORA A;  3MZZ A;  1YM9 A;  1RHS A;  3AAY A;  3UTN X;  1VEE A;  2MOL A;  3IPP A;  1YML A;  3NT6 A;  1YT8 A;  2IFV A;  4F67 A;  3ICR A;  3ILM A;  5LAO A;  1H4M X;  1CWS A;  1E0C A;  2EG4 B;  2JTS A;  2GWF A;  2EG4 A;  3P3A A;  2DCQ A;  3O3W A;  4JGT A;  1QB0 A;  1QXN A;  3TP9 A;  3ICT A;  5HBL A;  2A2K A;  2J6P A;  2KL3 A;  1DP2 A;  1YMD A;  3OP3 A;  3TG3 A;  2VSW A;  1BOH A;  1YMK A;  3HIX A;  3I3U A;  1GN0 A;  4WH7 A;  3F4A A;  3I2V A;  2JTR A;  1WV9 A;  2IFD A;  3IWH A; 
#chains in the Genus database with same CATH topology
 2EG3 A;  3TG1 B;  1BOI A;  4OCG A;  2UZQ A;  3AAX A;  5LAM A;  1URH A;  3K9R A;  5HPA A;  4WH9 A;  2WLR A;  2WLX A;  3GK5 A;  1T3K A;  3NTA A;  3FLH A;  3ICS A;  3FNJ A;  2Q82 A;  3G5J A;  1RHD A;  1CWT A;  3R2U A;  1C25 A;  2FSX A;  2MOI A;  3IPO A;  1GMX A;  2JTQ A;  3FOJ A;  5HBP A;  3NHV A;  1YS0 A;  1TQ1 A;  2K0Z A;  3OLH A;  1ORB A;  3D1P A;  1UAR A;  2MRM A;  2OUC A;  3NTD A;  5HBO A;  1WHB A;  3FS5 A;  1H4K X;  3HZU A;  1CWR A;  1OKG A;  2HHG A;  3HWI A;  5HBQ A;  1HZM A;  2ORA A;  3MZZ A;  1YM9 A;  1RHS A;  3AAY A;  3UTN X;  1VEE A;  2MOL A;  3IPP A;  1YML A;  3NT6 A;  1YT8 A;  2IFV A;  4F67 A;  3ICR A;  3ILM A;  5LAO A;  1H4M X;  1CWS A;  1E0C A;  2EG4 B;  2JTS A;  2GWF A;  2EG4 A;  3P3A A;  2DCQ A;  3O3W A;  4JGT A;  1QB0 A;  1QXN A;  3TP9 A;  3ICT A;  5HBL A;  2A2K A;  2J6P A;  2KL3 A;  1DP2 A;  1YMD A;  3OP3 A;  3TG3 A;  2VSW A;  1BOH A;  1YMK A;  3HIX A;  3I3U A;  1GN0 A;  4WH7 A;  3F4A A;  3I2V A;  2JTR A;  1WV9 A;  2IFD A;  3IWH A; 
#chains in the Genus database with same CATH homology
 2EG3 A;  3TG1 B;  1BOI A;  4OCG A;  2UZQ A;  3AAX A;  5LAM A;  1URH A;  3K9R A;  5HPA A;  4WH9 A;  2WLR A;  2WLX A;  3GK5 A;  1T3K A;  3NTA A;  3FLH A;  3ICS A;  3FNJ A;  3G5J A;  1RHD A;  1CWT A;  3R2U A;  1C25 A;  2FSX A;  2MOI A;  3IPO A;  1GMX A;  2JTQ A;  3FOJ A;  5HBP A;  3NHV A;  1YS0 A;  1TQ1 A;  2K0Z A;  3OLH A;  1ORB A;  3D1P A;  1UAR A;  2MRM A;  2OUC A;  3NTD A;  5HBO A;  1WHB A;  3FS5 A;  1H4K X;  3HZU A;  1CWR A;  1OKG A;  2HHG A;  3HWI A;  5HBQ A;  1HZM A;  2ORA A;  3MZZ A;  1YM9 A;  1RHS A;  3AAY A;  3UTN X;  1VEE A;  2MOL A;  3IPP A;  1YML A;  3NT6 A;  1YT8 A;  2IFV A;  4F67 A;  3ICR A;  3ILM A;  5LAO A;  1H4M X;  1CWS A;  1E0C A;  2EG4 B;  2JTS A;  2GWF A;  2EG4 A;  3P3A A;  2DCQ A;  3O3W A;  4JGT A;  1QB0 A;  1QXN A;  3TP9 A;  3ICT A;  5HBL A;  2A2K A;  2J6P A;  2KL3 A;  1DP2 A;  1YMD A;  3OP3 A;  3TG3 A;  2VSW A;  1BOH A;  1YMK A;  3HIX A;  3I3U A;  1GN0 A;  4WH7 A;  3F4A A;  3I2V A;  2JTR A;  1WV9 A;  2IFD A;  3IWH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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