4AJY | Genus

Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	27
sequence length	96
structure length	88
Chain Sequence	MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transcription
source organism	Homo sapiens
publication title	Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. pubmed doi rcsb
molecule keywords	TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2
total genus	27
structure length	88
sequence length	96
ec nomenclature
pdb deposition date	2012-02-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF03931	Skp1_POZ	Skp1 family, tetramerisation domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	4ajyC00

2E32B 2JZ3C 2FNJC 3HU6A 3ZRFB 4N9F5 2P1OA 4J8ZA 3E4UA 4EOZA 4U2NA 3C6NA 3ZNGB 4W9HH 5A6RA 2OVRA 3OGMA 3LNMB 4W9GB 4CP3A 3M52A 2NN2A 1EXBE 1FS1B 4AP2A 2MA9C 5EUPA 5H7GA 4WQOC 3HVEB 5HYWB 5BXDA 2OVPA 5DAFA 1R29A 3KVTA 1A68A 3OHVA 1BUOA 1FS2B 2C9WC 4B9KE 4BKTB 2PPIA 4AJYC 4W9HB 4JTAB 3C6OA 1VCBB 3HVEA 5BO4C 2VPKA 4UIJA 3LBZA 4W9DB 3ZRCB 3L2OA 5BXBA 2E31B 1NEXA 4I6JC 2P1MA 4W9EB 4CXTA 4HXIA 2P1PA 3OGLA 2ASSA 4CXJA 2NZ0B 2ASTA 5LLIB 3FKCA 2YY9A 1LM8C 1LQBB 1T1DA 3LUTB 3M8VA 4JTDB 4UYIA 1NN7A 3DRZA 4B95B 1CS3A 4JTCB 3HQIA 3OHUA 3WSOB 5IBKA 4W9JB 1QDVA 3GA1A 2R9RB 4BGCA 2A79B 3MKSA 2OVQA 3DCGB 5BXHA 4CRHA 3BIMA 4B9KB 5H7HA 1EOEA 2P1QA 5DADA 4U2MA 4CXIA 5HZGC 1QDWA 3ZUNB 1P22B 2Q81A 4W9KB 4JGHC 3ZTCB 4ZOUA 4APFA 1LDKD 2IF5A 1EOFA 4W9FB 1DSXA 3M5BA 1R28A 5JH5B 4U77A 2IZVC 3ZKJB 2IHCA 3C6PA 2Z8HA 5FTAA 3V7DA 3HTMA 4W9CB 1FQVB 4AWJB 3B84A 4W9LB 3I3NA 3ZTDB 1R2BA 2P1NA 3OGKA 2I2RA 3M4TA 2VKPA 1EODA 4W9IB 4BKSB 5A15A 1S1GA 1HV2A
chains in the Genus database with same CATH superfamily

2E32B 2JZ3C 2FNJC 3HU6A 3ZRFB 4N9F5 2P1OA 4J8ZA 3E4UA 4EOZA 4U2NA 3C6NA 3ZNGB 4W9HH 5A6RA 2OVRA 3OGMA 3LNMB 4W9GB 4CP3A 3M52A 2NN2A 1EXBE 1FS1B 4AP2A 2MA9C 5EUPA 5H7GA 4WQOC 3HVEB 5HYWB 5BXDA 2OVPA 5DAFA 1R29A 3KVTA 1A68A 3OHVA 1BUOA 1FS2B 2C9WC 4B9KE 4BKTB 2PPIA 4AJYC 4W9HB 4JTAB 3C6OA 1VCBB 3HVEA 5BO4C 2VPKA 4UIJA 3LBZA 4W9DB 3ZRCB 3L2OA 5BXBA 2E31B 1NEXA 4I6JC 2P1MA 4W9EB 4CXTA 4HXIA 2P1PA 3OGLA 2ASSA 4CXJA 2NZ0B 2ASTA 5LLIB 3FKCA 2YY9A 1LM8C 1LQBB 1T1DA 3LUTB 3M8VA 4JTDB 3DRXA 4UYIA 1NN7A 3DRZA 4B95B 1CS3A 4JTCB 3HQIA 3OHUA 3WSOB 5IBKA 4W9JB 3DRYA 1QDVA 3GA1A 2R9RB 4YY8A 4BGCA 2A79B 3MKSA 2OVQA 3DCGB 5BXHA 4CRHA 3BIMA 4B9KB 5H7HA 1EOEA 2P1QA 5DADA 4U2MA 4CXIA 5HZGC 1QDWA 3ZUNB 1P22B 2Q81A 4W9KB 4JGHC 3ZTCB 4ZOUA 4APFA 1LDKD 2IF5A 1EOFA 4W9FB 1DSXA 3M5BA 1R28A 5JH5B 4U77A 2IZVC 3ZKJB 2IHCA 3C6PA 2Z8HA 5FTAA 3V7DA 3HTMA 4W9CB 1FQVB 4AWJB 3B84A 4W9LB 3I3NA 3ZTDB 1R2BA 2P1NA 3OGKA 2I2RA 3M4TA 2VKPA 1EODA 4W9IB 4BKSB 5A15A 1S1GA 1HV2A 4ZGCA
chains in the Genus database with same CATH topology

2E32B 2JZ3C 2FNJC 3HU6A 3ZRFB 4N9F5 2P1OA 4J8ZA 3E4UA 4EOZA 4U2NA 3C6NA 3ZNGB 4W9HH 5A6RA 2OVRA 3OGMA 3LNMB 4W9GB 4CP3A 3M52A 2NN2A 1EXBE 1FS1B 4AP2A 2MA9C 5EUPA 5H7GA 4WQOC 3HVEB 5HYWB 5BXDA 2OVPA 5DAFA 1R29A 3KVTA 1A68A 3OHVA 1BUOA 1FS2B 2C9WC 4B9KE 4BKTB 2PPIA 4AJYC 4W9HB 4JTAB 3C6OA 1VCBB 3HVEA 5BO4C 2VPKA 4UIJA 3LBZA 4W9DB 3ZRCB 3L2OA 5BXBA 2E31B 1NEXA 4I6JC 2P1MA 4W9EB 4CXTA 4HXIA 2P1PA 3OGLA 2ASSA 4CXJA 2NZ0B 2ASTA 5LLIB 3FKCA 2YY9A 1LM8C 1LQBB 1T1DA 3LUTB 3M8VA 4JTDB 3DRXA 4UYIA 1NN7A 3DRZA 4B95B 1CS3A 4JTCB 3HQIA 3OHUA 3WSOB 5IBKA 4W9JB 3DRYA 1QDVA 3GA1A 2R9RB 4YY8A 4BGCA 2A79B 3MKSA 2OVQA 3DCGB 5BXHA 4CRHA 3BIMA 4B9KB 5H7HA 1EOEA 2P1QA 5DADA 4U2MA 4CXIA 5HZGC 1QDWA 3ZUNB 1P22B 2Q81A 4W9KB 4JGHC 3ZTCB 4ZOUA 4APFA 1LDKD 2IF5A 1EOFA 4W9FB 1DSXA 3M5BA 1R28A 5JH5B 4U77A 2IZVC 3ZKJB 2IHCA 3C6PA 2Z8HA 5FTAA 3V7DA 3HTMA 4W9CB 1FQVB 4AWJB 3B84A 4W9LB 3I3NA 3ZTDB 1R2BA 2P1NA 3OGKA 2I2RA 3M4TA 2VKPA 1EODA 4W9IB 4BKSB 5A15A 1S1GA 1HV2A 4ZGCA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2E32 B;  2JZ3 C;  2FNJ C;  3HU6 A;  3ZRF B;  4N9F 5;  2P1O A;  4J8Z A;  3E4U A;  4EOZ A;  4U2N A;  3C6N A;  3ZNG B;  4W9H H;  5A6R A;  2OVR A;  3OGM A;  3LNM B;  4W9G B;  4CP3 A;  3M52 A;  2NN2 A;  1EXB E;  1FS1 B;  4AP2 A;  2MA9 C;  5EUP A;  5H7G A;  4WQO C;  3HVE B;  5HYW B;  5BXD A;  2OVP A;  5DAF A;  1R29 A;  3KVT A;  1A68 A;  3OHV A;  1BUO A;  1FS2 B;  2C9W C;  4B9K E;  4BKT B;  2PPI A;  4AJY C;  4W9H B;  4JTA B;  3C6O A;  1VCB B;  3HVE A;  5BO4 C;  2VPK A;  4UIJ A;  3LBZ A;  4W9D B;  3ZRC B;  3L2O A;  5BXB A;  2E31 B;  1NEX A;  4I6J C;  2P1M A;  4W9E B;  4CXT A;  4HXI A;  2P1P A;  3OGL A;  2ASS A;  4CXJ A;  2NZ0 B;  2AST A;  5LLI B;  3FKC A;  2YY9 A;  1LM8 C;  1LQB B;  1T1D A;  3LUT B;  3M8V A;  4JTD B;  4UYI A;  1NN7 A;  3DRZ A;  4B95 B;  1CS3 A;  4JTC B;  3HQI A;  3OHU A;  3WSO B;  5IBK A;  4W9J B;  1QDV A;  3GA1 A;  2R9R B;  4BGC A;  2A79 B;  3MKS A;  2OVQ A;  3DCG B;  5BXH A;  4CRH A;  3BIM A;  4B9K B;  5H7H A;  1EOE A;  2P1Q A;  5DAD A;  4U2M A;  4CXI A;  5HZG C;  1QDW A;  3ZUN B;  1P22 B;  2Q81 A;  4W9K B;  4JGH C;  3ZTC B;  4ZOU A;  4APF A;  1LDK D;  2IF5 A;  1EOF A;  4W9F B;  1DSX A;  3M5B A;  1R28 A;  5JH5 B;  4U77 A;  2IZV C;  3ZKJ B;  2IHC A;  3C6P A;  2Z8H A;  5FTA A;  3V7D A;  3HTM A;  4W9C B;  1FQV B;  4AWJ B;  3B84 A;  4W9L B;  3I3N A;  3ZTD B;  1R2B A;  2P1N A;  3OGK A;  2I2R A;  3M4T A;  2VKP A;  1EOD A;  4W9I B;  4BKS B;  5A15 A;  1S1G A;  1HV2 A; 
#chains in the Genus database with same CATH topology
 2E32 B;  2JZ3 C;  2FNJ C;  3HU6 A;  3ZRF B;  4N9F 5;  2P1O A;  4J8Z A;  3E4U A;  4EOZ A;  4U2N A;  3C6N A;  3ZNG B;  4W9H H;  5A6R A;  2OVR A;  3OGM A;  3LNM B;  4W9G B;  4CP3 A;  3M52 A;  2NN2 A;  1EXB E;  1FS1 B;  4AP2 A;  2MA9 C;  5EUP A;  5H7G A;  4WQO C;  3HVE B;  5HYW B;  5BXD A;  2OVP A;  5DAF A;  1R29 A;  3KVT A;  1A68 A;  3OHV A;  1BUO A;  1FS2 B;  2C9W C;  4B9K E;  4BKT B;  2PPI A;  4AJY C;  4W9H B;  4JTA B;  3C6O A;  1VCB B;  3HVE A;  5BO4 C;  2VPK A;  4UIJ A;  3LBZ A;  4W9D B;  3ZRC B;  3L2O A;  5BXB A;  2E31 B;  1NEX A;  4I6J C;  2P1M A;  4W9E B;  4CXT A;  4HXI A;  2P1P A;  3OGL A;  2ASS A;  4CXJ A;  2NZ0 B;  2AST A;  5LLI B;  3FKC A;  2YY9 A;  1LM8 C;  1LQB B;  1T1D A;  3LUT B;  3M8V A;  4JTD B;  3DRX A;  4UYI A;  1NN7 A;  3DRZ A;  4B95 B;  1CS3 A;  4JTC B;  3HQI A;  3OHU A;  3WSO B;  5IBK A;  4W9J B;  3DRY A;  1QDV A;  3GA1 A;  2R9R B;  4YY8 A;  4BGC A;  2A79 B;  3MKS A;  2OVQ A;  3DCG B;  5BXH A;  4CRH A;  3BIM A;  4B9K B;  5H7H A;  1EOE A;  2P1Q A;  5DAD A;  4U2M A;  4CXI A;  5HZG C;  1QDW A;  3ZUN B;  1P22 B;  2Q81 A;  4W9K B;  4JGH C;  3ZTC B;  4ZOU A;  4APF A;  1LDK D;  2IF5 A;  1EOF A;  4W9F B;  1DSX A;  3M5B A;  1R28 A;  5JH5 B;  4U77 A;  2IZV C;  3ZKJ B;  2IHC A;  3C6P A;  2Z8H A;  5FTA A;  3V7D A;  3HTM A;  4W9C B;  1FQV B;  4AWJ B;  3B84 A;  4W9L B;  3I3N A;  3ZTD B;  1R2B A;  2P1N A;  3OGK A;  2I2R A;  3M4T A;  2VKP A;  1EOD A;  4W9I B;  4BKS B;  5A15 A;  1S1G A;  1HV2 A;  4ZGC A; 
#chains in the Genus database with same CATH homology
 2E32 B;  2JZ3 C;  2FNJ C;  3HU6 A;  3ZRF B;  4N9F 5;  2P1O A;  4J8Z A;  3E4U A;  4EOZ A;  4U2N A;  3C6N A;  3ZNG B;  4W9H H;  5A6R A;  2OVR A;  3OGM A;  3LNM B;  4W9G B;  4CP3 A;  3M52 A;  2NN2 A;  1EXB E;  1FS1 B;  4AP2 A;  2MA9 C;  5EUP A;  5H7G A;  4WQO C;  3HVE B;  5HYW B;  5BXD A;  2OVP A;  5DAF A;  1R29 A;  3KVT A;  1A68 A;  3OHV A;  1BUO A;  1FS2 B;  2C9W C;  4B9K E;  4BKT B;  2PPI A;  4AJY C;  4W9H B;  4JTA B;  3C6O A;  1VCB B;  3HVE A;  5BO4 C;  2VPK A;  4UIJ A;  3LBZ A;  4W9D B;  3ZRC B;  3L2O A;  5BXB A;  2E31 B;  1NEX A;  4I6J C;  2P1M A;  4W9E B;  4CXT A;  4HXI A;  2P1P A;  3OGL A;  2ASS A;  4CXJ A;  2NZ0 B;  2AST A;  5LLI B;  3FKC A;  2YY9 A;  1LM8 C;  1LQB B;  1T1D A;  3LUT B;  3M8V A;  4JTD B;  3DRX A;  4UYI A;  1NN7 A;  3DRZ A;  4B95 B;  1CS3 A;  4JTC B;  3HQI A;  3OHU A;  3WSO B;  5IBK A;  4W9J B;  3DRY A;  1QDV A;  3GA1 A;  2R9R B;  4YY8 A;  4BGC A;  2A79 B;  3MKS A;  2OVQ A;  3DCG B;  5BXH A;  4CRH A;  3BIM A;  4B9K B;  5H7H A;  1EOE A;  2P1Q A;  5DAD A;  4U2M A;  4CXI A;  5HZG C;  1QDW A;  3ZUN B;  1P22 B;  2Q81 A;  4W9K B;  4JGH C;  3ZTC B;  4ZOU A;  4APF A;  1LDK D;  2IF5 A;  1EOF A;  4W9F B;  1DSX A;  3M5B A;  1R28 A;  5JH5 B;  4U77 A;  2IZV C;  3ZKJ B;  2IHC A;  3C6P A;  2Z8H A;  5FTA A;  3V7D A;  3HTM A;  4W9C B;  1FQV B;  4AWJ B;  3B84 A;  4W9L B;  3I3N A;  3ZTD B;  1R2B A;  2P1N A;  3OGK A;  2I2R A;  3M4T A;  2VKP A;  1EOD A;  4W9I B;  4BKS B;  5A15 A;  1S1G A;  1HV2 A;  4ZGC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4AJYC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations