4B9K | Genus

Total Genus 25

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	25
sequence length	97
structure length	88
Chain Sequence	MMYVKLISSDGHEFIVKREHALTSGTIKAMLSTNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 88 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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88 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ligase
source organism	Homo sapiens
publication title	Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha pubmed doi rcsb
molecule keywords	TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2
total genus	25
structure length	88
sequence length	97
chains with identical sequence	H, K
ec nomenclature
pdb deposition date	2012-09-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF03931	Skp1_POZ	Skp1 family, tetramerisation domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	4b9kB00

5A15A 4AJYC 2R9RB 4I6JC 3B84A 1S1GA 2E31B 3GA1A 5H7HA 3LBZA 4BKSB 1LM8C 3M8VA 5DAFA 2C9WC 1FQVB 5H7GA 3HTMA 4U2MA 1R28A 1T1DA 2ASTA 4AWJB 2OVRA 2Z8HA 4W9GB 3OHUA 5JH5B 3C6PA 4CXIA 2JZ3C 4W9EB 3M4TA 3ZRCB 3BIMA 3LUTB 1CS3A 1EODA 4W9IB 4N9F5 5BO4C 4HXIA 2IZVC 1HV2A 3HQIA 3ZUNB 2E32B 4ZOUA 4W9JB 4BGCA 3ZTDB 4JTDB 1VCBB 1P22B 3KVTA 1LQBB 3M5BA 2OVQA 3I3NA 3OHVA 4W9HB 4WQOC 3ZKJB 5BXBA 4JTCB 1R29A 2FNJC 2ASSA 3ZTCB 4W9FB 2P1MA 1EXBE 4W9KB 5FTAA 4UYIA 3LNMB 4UIJA 1DSXA 4W9HH 2NZ0B 2Q81A 4BKTB 4AP2A 3HU6A 5HYWB 3OGMA 1FS2B 5IBKA 2IF5A 3M52A 1QDVA 4B9KB 3L2OA 3C6OA 5A6RA 3HVEA 4U2NA 5DADA 4U77A 1EOFA 1QDWA 3HVEB 4JGHC 2IHCA 5BXHA 2NN2A 2P1NA 2VKPA 2VPKA 1NN7A 2MA9C 4W9LB 3FKCA 3C6NA 3DCGB 4CP3A 3OGLA 3ZRFB 1BUOA 1R2BA 3DRZA 2YY9A 2OVPA 4JTAB 4B95B 2PPIA 3WSOB 3OGKA 5EUPA 3V7DA 2P1PA 4W9DB 4CXTA 3E4UA 4J8ZA 5HZGC 4W9CB 4CRHA 2P1OA 4B9KE 1NEXA 3MKSA 1LDKD 2A79B 2P1QA 3ZNGB 1A68A 4APFA 4EOZA 5LLIB 2I2RA 1EOEA 1FS1B 4CXJA 5BXDA
chains in the Genus database with same CATH superfamily

4YY8A 4AJYC 5A15A 2R9RB 4I6JC 3B84A 1S1GA 2E31B 3GA1A 5H7HA 3LBZA 3DRXA 4BKSB 1LM8C 3M8VA 5DAFA 2C9WC 1FQVB 5H7GA 3HTMA 4U2MA 1R28A 1T1DA 2ASTA 4AWJB 2OVRA 2Z8HA 4W9GB 3OHUA 5JH5B 3C6PA 4CXIA 2JZ3C 4W9EB 3M4TA 3ZRCB 3BIMA 3LUTB 1CS3A 1EODA 4W9IB 4N9F5 5BO4C 4HXIA 2IZVC 1HV2A 3HQIA 3ZUNB 2E32B 4ZOUA 4W9JB 4BGCA 3ZTDB 4JTDB 1VCBB 1P22B 3KVTA 1LQBB 3M5BA 2OVQA 3I3NA 3OHVA 4W9HB 4WQOC 3ZKJB 5BXBA 4JTCB 1R29A 2FNJC 2ASSA 3ZTCB 4W9FB 3DRYA 2P1MA 1EXBE 4W9KB 5FTAA 4UYIA 3LNMB 4UIJA 1DSXA 4W9HH 2NZ0B 2Q81A 4BKTB 4AP2A 3HU6A 5HYWB 3OGMA 1FS2B 5IBKA 2IF5A 3M52A 1QDVA 4B9KB 3L2OA 3C6OA 5A6RA 3HVEA 4U2NA 5DADA 4U77A 1EOFA 1QDWA 3HVEB 4JGHC 2IHCA 5BXHA 2NN2A 2P1NA 2VKPA 2VPKA 1NN7A 2MA9C 4W9LB 3FKCA 3C6NA 3DCGB 4CP3A 3OGLA 3ZRFB 1BUOA 1R2BA 3DRZA 2YY9A 2OVPA 4JTAB 4B95B 2PPIA 3WSOB 3OGKA 5EUPA 3V7DA 2P1PA 4W9DB 4CXTA 3E4UA 4J8ZA 5HZGC 4W9CB 4CRHA 4ZGCA 2P1OA 4B9KE 1NEXA 3MKSA 1LDKD 2A79B 2P1QA 3ZNGB 1A68A 4APFA 4EOZA 5LLIB 2I2RA 1EOEA 1FS1B 4CXJA 5BXDA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5A15 A;  4AJY C;  2R9R B;  4I6J C;  3B84 A;  1S1G A;  2E31 B;  3GA1 A;  5H7H A;  3LBZ A;  4BKS B;  1LM8 C;  3M8V A;  5DAF A;  2C9W C;  1FQV B;  5H7G A;  3HTM A;  4U2M A;  1R28 A;  1T1D A;  2AST A;  4AWJ B;  2OVR A;  2Z8H A;  4W9G B;  3OHU A;  5JH5 B;  3C6P A;  4CXI A;  2JZ3 C;  4W9E B;  3M4T A;  3ZRC B;  3BIM A;  3LUT B;  1CS3 A;  1EOD A;  4W9I B;  4N9F 5;  5BO4 C;  4HXI A;  2IZV C;  1HV2 A;  3HQI A;  3ZUN B;  2E32 B;  4ZOU A;  4W9J B;  4BGC A;  3ZTD B;  4JTD B;  1VCB B;  1P22 B;  3KVT A;  1LQB B;  3M5B A;  2OVQ A;  3I3N A;  3OHV A;  4W9H B;  4WQO C;  3ZKJ B;  5BXB A;  4JTC B;  1R29 A;  2FNJ C;  2ASS A;  3ZTC B;  4W9F B;  2P1M A;  1EXB E;  4W9K B;  5FTA A;  4UYI A;  3LNM B;  4UIJ A;  1DSX A;  4W9H H;  2NZ0 B;  2Q81 A;  4BKT B;  4AP2 A;  3HU6 A;  5HYW B;  3OGM A;  1FS2 B;  5IBK A;  2IF5 A;  3M52 A;  1QDV A;  4B9K B;  3L2O A;  3C6O A;  5A6R A;  3HVE A;  4U2N A;  5DAD A;  4U77 A;  1EOF A;  1QDW A;  3HVE B;  4JGH C;  2IHC A;  5BXH A;  2NN2 A;  2P1N A;  2VKP A;  2VPK A;  1NN7 A;  2MA9 C;  4W9L B;  3FKC A;  3C6N A;  3DCG B;  4CP3 A;  3OGL A;  3ZRF B;  1BUO A;  1R2B A;  3DRZ A;  2YY9 A;  2OVP A;  4JTA B;  4B95 B;  2PPI A;  3WSO B;  3OGK A;  5EUP A;  3V7D A;  2P1P A;  4W9D B;  4CXT A;  3E4U A;  4J8Z A;  5HZG C;  4W9C B;  4CRH A;  2P1O A;  4B9K E;  1NEX A;  3MKS A;  1LDK D;  2A79 B;  2P1Q A;  3ZNG B;  1A68 A;  4APF A;  4EOZ A;  5LLI B;  2I2R A;  1EOE A;  1FS1 B;  4CXJ A;  5BXD A; 
#chains in the Genus database with same CATH topology
 4YY8 A;  4AJY C;  5A15 A;  2R9R B;  4I6J C;  3B84 A;  1S1G A;  2E31 B;  3GA1 A;  5H7H A;  3LBZ A;  3DRX A;  4BKS B;  1LM8 C;  3M8V A;  5DAF A;  2C9W C;  1FQV B;  5H7G A;  3HTM A;  4U2M A;  1R28 A;  1T1D A;  2AST A;  4AWJ B;  2OVR A;  2Z8H A;  4W9G B;  3OHU A;  5JH5 B;  3C6P A;  4CXI A;  2JZ3 C;  4W9E B;  3M4T A;  3ZRC B;  3BIM A;  3LUT B;  1CS3 A;  1EOD A;  4W9I B;  4N9F 5;  5BO4 C;  4HXI A;  2IZV C;  1HV2 A;  3HQI A;  3ZUN B;  2E32 B;  4ZOU A;  4W9J B;  4BGC A;  3ZTD B;  4JTD B;  1VCB B;  1P22 B;  3KVT A;  1LQB B;  3M5B A;  2OVQ A;  3I3N A;  3OHV A;  4W9H B;  4WQO C;  3ZKJ B;  5BXB A;  4JTC B;  1R29 A;  2FNJ C;  2ASS A;  3ZTC B;  4W9F B;  3DRY A;  2P1M A;  1EXB E;  4W9K B;  5FTA A;  4UYI A;  3LNM B;  4UIJ A;  1DSX A;  4W9H H;  2NZ0 B;  2Q81 A;  4BKT B;  4AP2 A;  3HU6 A;  5HYW B;  3OGM A;  1FS2 B;  5IBK A;  2IF5 A;  3M52 A;  1QDV A;  4B9K B;  3L2O A;  3C6O A;  5A6R A;  3HVE A;  4U2N A;  5DAD A;  4U77 A;  1EOF A;  1QDW A;  3HVE B;  4JGH C;  2IHC A;  5BXH A;  2NN2 A;  2P1N A;  2VKP A;  2VPK A;  1NN7 A;  2MA9 C;  4W9L B;  3FKC A;  3C6N A;  3DCG B;  4CP3 A;  3OGL A;  3ZRF B;  1BUO A;  1R2B A;  3DRZ A;  2YY9 A;  2OVP A;  4JTA B;  4B95 B;  2PPI A;  3WSO B;  3OGK A;  5EUP A;  3V7D A;  2P1P A;  4W9D B;  4CXT A;  3E4U A;  4J8Z A;  5HZG C;  4W9C B;  4CRH A;  4ZGC A;  2P1O A;  4B9K E;  1NEX A;  3MKS A;  1LDK D;  2A79 B;  2P1Q A;  3ZNG B;  1A68 A;  4APF A;  4EOZ A;  5LLI B;  2I2R A;  1EOE A;  1FS1 B;  4CXJ A;  5BXD A; 
#chains in the Genus database with same CATH homology
 4YY8 A;  4AJY C;  5A15 A;  2R9R B;  4I6J C;  3B84 A;  1S1G A;  2E31 B;  3GA1 A;  5H7H A;  3LBZ A;  3DRX A;  4BKS B;  1LM8 C;  3M8V A;  5DAF A;  2C9W C;  1FQV B;  5H7G A;  3HTM A;  4U2M A;  1R28 A;  1T1D A;  2AST A;  4AWJ B;  2OVR A;  2Z8H A;  4W9G B;  3OHU A;  5JH5 B;  3C6P A;  4CXI A;  2JZ3 C;  4W9E B;  3M4T A;  3ZRC B;  3BIM A;  3LUT B;  1CS3 A;  1EOD A;  4W9I B;  4N9F 5;  5BO4 C;  4HXI A;  2IZV C;  1HV2 A;  3HQI A;  3ZUN B;  2E32 B;  4ZOU A;  4W9J B;  4BGC A;  3ZTD B;  4JTD B;  1VCB B;  1P22 B;  3KVT A;  1LQB B;  3M5B A;  2OVQ A;  3I3N A;  3OHV A;  4W9H B;  4WQO C;  3ZKJ B;  5BXB A;  4JTC B;  1R29 A;  2FNJ C;  2ASS A;  3ZTC B;  4W9F B;  3DRY A;  2P1M A;  1EXB E;  4W9K B;  5FTA A;  4UYI A;  3LNM B;  4UIJ A;  1DSX A;  4W9H H;  2NZ0 B;  2Q81 A;  4BKT B;  4AP2 A;  3HU6 A;  5HYW B;  3OGM A;  1FS2 B;  5IBK A;  2IF5 A;  3M52 A;  1QDV A;  4B9K B;  3L2O A;  3C6O A;  5A6R A;  3HVE A;  4U2N A;  5DAD A;  4U77 A;  1EOF A;  1QDW A;  3HVE B;  4JGH C;  2IHC A;  5BXH A;  2NN2 A;  2P1N A;  2VKP A;  2VPK A;  1NN7 A;  2MA9 C;  4W9L B;  3FKC A;  3C6N A;  3DCG B;  4CP3 A;  3OGL A;  3ZRF B;  1BUO A;  1R2B A;  3DRZ A;  2YY9 A;  2OVP A;  4JTA B;  4B95 B;  2PPI A;  3WSO B;  3OGK A;  5EUP A;  3V7D A;  2P1P A;  4W9D B;  4CXT A;  3E4U A;  4J8Z A;  5HZG C;  4W9C B;  4CRH A;  4ZGC A;  2P1O A;  4B9K E;  1NEX A;  3MKS A;  1LDK D;  2A79 B;  2P1Q A;  3ZNG B;  1A68 A;  4APF A;  4EOZ A;  5LLI B;  2I2R A;  1EOE A;  1FS1 B;  4CXJ A;  5BXD A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4B9KB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations