4BKSB

Von hippel lindau protein:elonginb:elonginc complex, in complex with (2s,4r)-1-ethanoyl-n-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide
Total Genus 25

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
96
structure length
87
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSTNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
S1 (18-22)TI1 (23-26)EMPTYS2 (28-32)AH1 (33-37)AH2 (40-47)S3 (59-61)TI2 (62-65)AH3 (67-83)TII1 (83-86)Updating...
connected with : NaN
molecule tags Protein transport
source organism Homo sapiens
publication title Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
pubmed doi rcsb
molecule keywords TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2
total genus 25
structure length 87
sequence length 96
chains with identical sequence E, H, K
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 4bksB00
1VCBB 2P1PA 1DSXA 2FNJC 2I2RA 5IBKA 4U2MA 4JTDB 1QDVA 1EOFA 2NN2A 3I3NA 3ZNGB 3C6OA 3GA1A 4W9EB 1EOEA 1FS2B 5A15A 4CXIA 5BO4C 4CP3A 4JTAB 2R9RB 1CS3A 1EODA 3LUTB 1R28A 3M8VA 3OHUA 4AJYC 3M4TA 4AP2A 1S1GA 3LNMB 4BKTB 4CRHA 3V7DA 2OVPA 3HTMA 3ZKJB 5BXBA 3E4UA 4B9KE 4CXTA 1EXBE 3OHVA 4B95B 3B84A 3DRZA 3KVTA 4CXJA 1HV2A 2IHCA 3HU6A 3DCGB 3OGMA 2P1QA 4W9HB 4W9GB 3ZUNB 2PPIA 3ZRFB 3L2OA 1BUOA 3M52A 2C9WC 4EOZA 2P1MA 1NN7A 5JH5B 1T1DA 3C6NA 2E31B 5HYWB 2OVQA 3BIMA 4UYIA 4U2NA 2A79B 5H7GA 4UIJA 2YY9A 2VKPA 2Z8HA 1QDWA 4HXIA 1A68A 2MA9C 4JGHC 1NEXA 5A6RA 4WQOC 2P1OA 1R29A 5HZGC 2NZ0B 4N9F5 3FKCA 1FS1B 4B9KB 4W9IB 4BKSB 2IZVC 3C6PA 3HQIA 2P1NA 3WSOB 3LBZA 5H7HA 4APFA 4W9CB 4W9FB 1FQVB 4JTCB 3ZTDB 4U77A 2Q81A 1LQBB 4W9DB 5DAFA 3HVEA 4BGCA 4AWJB 3M5BA 3OGKA 3HVEB 4W9LB 5BXDA 5BXHA 5LLIB 4W9HH 5FTAA 3ZRCB 1R2BA 4ZOUA 3ZTCB 3OGLA 2ASTA 2JZ3C 1P22B 4W9JB 1LDKD 5DADA 4J8ZA 5EUPA 2E32B 2OVRA 4I6JC 2ASSA 2IF5A 3MKSA 2VPKA 4W9KB 1LM8C
chains in the Genus database with same CATH superfamily
1VCBB 2P1PA 1DSXA 2FNJC 2I2RA 5IBKA 4U2MA 4JTDB 1QDVA 1EOFA 2NN2A 3I3NA 3ZNGB 4YY8A 3C6OA 3GA1A 4W9EB 1EOEA 1FS2B 5A15A 4CXIA 5BO4C 4CP3A 4JTAB 2R9RB 1CS3A 1EODA 3LUTB 1R28A 3M8VA 3OHUA 4AJYC 3M4TA 4AP2A 1S1GA 3LNMB 4BKTB 4CRHA 3V7DA 2OVPA 3HTMA 3ZKJB 5BXBA 3E4UA 4B9KE 4CXTA 1EXBE 3OHVA 4B95B 3B84A 3DRZA 3KVTA 4CXJA 1HV2A 2IHCA 3HU6A 3DCGB 3OGMA 2P1QA 4W9HB 4W9GB 3ZUNB 2PPIA 3ZRFB 3L2OA 1BUOA 3M52A 2C9WC 4EOZA 2P1MA 1NN7A 5JH5B 1T1DA 3C6NA 2E31B 5HYWB 2OVQA 3BIMA 4UYIA 4U2NA 2A79B 5H7GA 4UIJA 2YY9A 2VKPA 2Z8HA 1QDWA 4HXIA 1A68A 2MA9C 4JGHC 1NEXA 5A6RA 4WQOC 2P1OA 1R29A 3DRXA 5HZGC 2NZ0B 4N9F5 3FKCA 1FS1B 4B9KB 4W9IB 4BKSB 2IZVC 3C6PA 3HQIA 2P1NA 3WSOB 3LBZA 5H7HA 4APFA 4W9CB 4W9FB 1FQVB 4JTCB 3ZTDB 4U77A 2Q81A 1LQBB 4W9DB 5DAFA 3HVEA 4BGCA 4AWJB 3M5BA 4ZGCA 3OGKA 3HVEB 4W9LB 5BXDA 5BXHA 5LLIB 4W9HH 5FTAA 3ZRCB 1R2BA 3DRYA 4ZOUA 3ZTCB 3OGLA 2ASTA 2JZ3C 1P22B 4W9JB 1LDKD 5DADA 4J8ZA 5EUPA 2E32B 2OVRA 4I6JC 2ASSA 2IF5A 3MKSA 2VPKA 4W9KB 1LM8C
chains in the Genus database with same CATH topology
1VCBB 2P1PA 1DSXA 2FNJC 2I2RA 5IBKA 4U2MA 4JTDB 1QDVA 1EOFA 2NN2A 3I3NA 3ZNGB 4YY8A 3C6OA 3GA1A 4W9EB 1EOEA 1FS2B 5A15A 4CXIA 5BO4C 4CP3A 4JTAB 2R9RB 1CS3A 1EODA 3LUTB 1R28A 3M8VA 3OHUA 4AJYC 3M4TA 4AP2A 1S1GA 3LNMB 4BKTB 4CRHA 3V7DA 2OVPA 3HTMA 3ZKJB 5BXBA 3E4UA 4B9KE 4CXTA 1EXBE 3OHVA 4B95B 3B84A 3DRZA 3KVTA 4CXJA 1HV2A 2IHCA 3HU6A 3DCGB 3OGMA 2P1QA 4W9HB 4W9GB 3ZUNB 2PPIA 3ZRFB 3L2OA 1BUOA 3M52A 2C9WC 4EOZA 2P1MA 1NN7A 5JH5B 1T1DA 3C6NA 2E31B 5HYWB 2OVQA 3BIMA 4UYIA 4U2NA 2A79B 5H7GA 4UIJA 2YY9A 2VKPA 2Z8HA 1QDWA 4HXIA 1A68A 2MA9C 4JGHC 1NEXA 5A6RA 4WQOC 2P1OA 1R29A 3DRXA 5HZGC 2NZ0B 4N9F5 3FKCA 1FS1B 4B9KB 4W9IB 4BKSB 2IZVC 3C6PA 3HQIA 2P1NA 3WSOB 3LBZA 5H7HA 4APFA 4W9CB 4W9FB 1FQVB 4JTCB 3ZTDB 4U77A 2Q81A 1LQBB 4W9DB 5DAFA 3HVEA 4BGCA 4AWJB 3M5BA 4ZGCA 3OGKA 3HVEB 4W9LB 5BXDA 5BXHA 5LLIB 4W9HH 5FTAA 3ZRCB 1R2BA 3DRYA 4ZOUA 3ZTCB 3OGLA 2ASTA 2JZ3C 1P22B 4W9JB 1LDKD 5DADA 4J8ZA 5EUPA 2E32B 2OVRA 4I6JC 2ASSA 2IF5A 3MKSA 2VPKA 4W9KB 1LM8C
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1VCB B;  2P1P A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1QDV A;  1EOF A;  2NN2 A;  3I3N A;  3ZNG B;  3C6O A;  3GA1 A;  4W9E B;  1EOE A;  1FS2 B;  5A15 A;  4CXI A;  5BO4 C;  4CP3 A;  4JTA B;  2R9R B;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  4CRH A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  3E4U A;  4B9K E;  4CXT A;  1EXB E;  3OHV A;  4B95 B;  3B84 A;  3DRZ A;  3KVT A;  4CXJ A;  1HV2 A;  2IHC A;  3HU6 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  4W9G B;  3ZUN B;  2PPI A;  3ZRF B;  3L2O A;  1BUO A;  3M52 A;  2C9W C;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  4WQO C;  2P1O A;  1R29 A;  5HZG C;  2NZ0 B;  4N9F 5;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3C6P A;  3HQI A;  2P1N A;  3WSO B;  3LBZ A;  5H7H A;  4APF A;  4W9C B;  4W9F B;  1FQV B;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  4W9D B;  5DAF A;  3HVE A;  4BGC A;  4AWJ B;  3M5B A;  3OGK A;  3HVE B;  4W9L B;  5BXD A;  5BXH A;  5LLI B;  4W9H H;  5FTA A;  3ZRC B;  1R2B A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  5EUP A;  2E32 B;  2OVR A;  4I6J C;  2ASS A;  2IF5 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C; 
#chains in the Genus database with same CATH topology
 1VCB B;  2P1P A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1QDV A;  1EOF A;  2NN2 A;  3I3N A;  3ZNG B;  4YY8 A;  3C6O A;  3GA1 A;  4W9E B;  1EOE A;  1FS2 B;  5A15 A;  4CXI A;  5BO4 C;  4CP3 A;  4JTA B;  2R9R B;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  4CRH A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  3E4U A;  4B9K E;  4CXT A;  1EXB E;  3OHV A;  4B95 B;  3B84 A;  3DRZ A;  3KVT A;  4CXJ A;  1HV2 A;  2IHC A;  3HU6 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  4W9G B;  3ZUN B;  2PPI A;  3ZRF B;  3L2O A;  1BUO A;  3M52 A;  2C9W C;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  4WQO C;  2P1O A;  1R29 A;  3DRX A;  5HZG C;  2NZ0 B;  4N9F 5;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3C6P A;  3HQI A;  2P1N A;  3WSO B;  3LBZ A;  5H7H A;  4APF A;  4W9C B;  4W9F B;  1FQV B;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  4W9D B;  5DAF A;  3HVE A;  4BGC A;  4AWJ B;  3M5B A;  4ZGC A;  3OGK A;  3HVE B;  4W9L B;  5BXD A;  5BXH A;  5LLI B;  4W9H H;  5FTA A;  3ZRC B;  1R2B A;  3DRY A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  5EUP A;  2E32 B;  2OVR A;  4I6J C;  2ASS A;  2IF5 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C; 
#chains in the Genus database with same CATH homology
 1VCB B;  2P1P A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1QDV A;  1EOF A;  2NN2 A;  3I3N A;  3ZNG B;  4YY8 A;  3C6O A;  3GA1 A;  4W9E B;  1EOE A;  1FS2 B;  5A15 A;  4CXI A;  5BO4 C;  4CP3 A;  4JTA B;  2R9R B;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  4CRH A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  3E4U A;  4B9K E;  4CXT A;  1EXB E;  3OHV A;  4B95 B;  3B84 A;  3DRZ A;  3KVT A;  4CXJ A;  1HV2 A;  2IHC A;  3HU6 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  4W9G B;  3ZUN B;  2PPI A;  3ZRF B;  3L2O A;  1BUO A;  3M52 A;  2C9W C;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  4WQO C;  2P1O A;  1R29 A;  3DRX A;  5HZG C;  2NZ0 B;  4N9F 5;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3C6P A;  3HQI A;  2P1N A;  3WSO B;  3LBZ A;  5H7H A;  4APF A;  4W9C B;  4W9F B;  1FQV B;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  4W9D B;  5DAF A;  3HVE A;  4BGC A;  4AWJ B;  3M5B A;  4ZGC A;  3OGK A;  3HVE B;  4W9L B;  5BXD A;  5BXH A;  5LLI B;  4W9H H;  5FTA A;  3ZRC B;  1R2B A;  3DRY A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  5EUP A;  2E32 B;  2OVR A;  4I6J C;  2ASS A;  2IF5 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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