4CP3A

The structure of bcl6 btb (poz) domain in complex with the ansamycin antibiotic rifabutin.
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
122
structure length
122
Chain Sequence
ASQIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKRNLSVINLDPEINPEGFNILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords B-CELL LYMPHOMA 6 PROTEIN
total genus 40
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 4cp3A00
5IBKA 3LNMB 3V7DA 2NN2A 4B95B 3OGKA 4W9CB 4W9LB 3ZKJB 4W9DB 2JZ3C 3KVTA 1LM8C 1EOEA 3C6NA 5A15A 5DADA 3OGMA 3WSOB 1QDVA 4W9GB 1FQVB 1R29A 3LUTB 4W9KB 5JH5B 5BXBA 1LDKD 3FKCA 3LBZA 2VKPA 2IZVC 1R2BA 4BGCA 3ZRCB 2IHCA 4CRHA 4CP3A 1T1DA 4U2NA 1EXBE 3M52A 2I2RA 3HTMA 5HZGC 4W9FB 4WQOC 1A68A 2A79B 3ZTCB 5H7HA 5FTAA 2OVPA 2YY9A 5A6RA 4W9JB 1R28A 4JTDB 3BIMA 4U2MA 4I6JC 4W9HB 1VCBB 2FNJC 3MKSA 4B9KB 1LQBB 4BKTB 5BXDA 4ZOUA 4JGHC 3M4TA 1QDWA 3C6OA 2MA9C 1DSXA 2ASTA 4HXIA 3OGLA 5BO4C 4EOZA 5LLIB 5EUPA 2P1OA 1NEXA 2C9WC 1HV2A 3M8VA 2NZ0B 3I3NA 3ZTDB 5BXHA 1NN7A 4N9F5 3HVEB 4W9EB 4UYIA 4CXIA 1EODA 3E4UA 3HU6A 4W9IB 1FS1B 4U77A 4APFA 2P1QA 4J8ZA 4UIJA 3HQIA 3ZRFB 3OHVA 3C6PA 3GA1A 5H7GA 1BUOA 4W9HH 3B84A 1CS3A 1P22B 4B9KE 2IF5A 1S1GA 2OVRA 2OVQA 4AP2A 2P1MA 5DAFA 2P1NA 4BKSB 2E31B 1EOFA 2Q81A 2VPKA 3DCGB 4AWJB 4CXJA 4JTCB 3DRZA 2E32B 2PPIA 4JTAB 2Z8HA 3L2OA 3OHUA 3ZUNB 5HYWB 3M5BA 2P1PA 3ZNGB 2ASSA 4AJYC 4CXTA 3HVEA 1FS2B 2R9RB
chains in the Genus database with same CATH superfamily
5IBKA 3LNMB 3V7DA 2NN2A 4B95B 3OGKA 4W9CB 4W9LB 3DRXA 3ZKJB 4W9DB 2JZ3C 3KVTA 1LM8C 1EOEA 3C6NA 5A15A 5DADA 3OGMA 3WSOB 4ZGCA 1QDVA 4W9GB 1FQVB 1R29A 3LUTB 4W9KB 3DRYA 5JH5B 5BXBA 1LDKD 3FKCA 3LBZA 2VKPA 2IZVC 1R2BA 4BGCA 3ZRCB 2IHCA 4CRHA 4CP3A 1T1DA 4U2NA 1EXBE 3M52A 2I2RA 3HTMA 5HZGC 4W9FB 4WQOC 1A68A 2A79B 3ZTCB 5H7HA 5FTAA 2OVPA 2YY9A 5A6RA 4W9JB 1R28A 4JTDB 3BIMA 4U2MA 4I6JC 4W9HB 1VCBB 2FNJC 3MKSA 4B9KB 1LQBB 4BKTB 5BXDA 4ZOUA 4JGHC 3M4TA 1QDWA 3C6OA 2MA9C 1DSXA 2ASTA 4HXIA 3OGLA 5BO4C 4EOZA 5LLIB 5EUPA 2P1OA 1NEXA 2C9WC 1HV2A 3M8VA 2NZ0B 3I3NA 3ZTDB 5BXHA 1NN7A 4N9F5 3HVEB 4W9EB 4UYIA 4CXIA 1EODA 3E4UA 3HU6A 4W9IB 1FS1B 4U77A 4APFA 2P1QA 4J8ZA 4UIJA 3HQIA 3ZRFB 3OHVA 3C6PA 3GA1A 5H7GA 1BUOA 4W9HH 3B84A 1CS3A 1P22B 4B9KE 4YY8A 2IF5A 1S1GA 2OVRA 2OVQA 4AP2A 2P1MA 5DAFA 2P1NA 4BKSB 2E31B 1EOFA 2Q81A 2VPKA 3DCGB 4AWJB 4CXJA 4JTCB 3DRZA 2E32B 2PPIA 4JTAB 2Z8HA 3L2OA 3OHUA 3ZUNB 5HYWB 3M5BA 2P1PA 3ZNGB 2ASSA 4AJYC 4CXTA 3HVEA 1FS2B 2R9RB
chains in the Genus database with same CATH topology
5IBKA 3LNMB 3V7DA 2NN2A 4B95B 3OGKA 4W9CB 4W9LB 3DRXA 3ZKJB 4W9DB 2JZ3C 3KVTA 1LM8C 1EOEA 3C6NA 5A15A 5DADA 3OGMA 3WSOB 4ZGCA 1QDVA 4W9GB 1FQVB 1R29A 3LUTB 4W9KB 3DRYA 5JH5B 5BXBA 1LDKD 3FKCA 3LBZA 2VKPA 2IZVC 1R2BA 4BGCA 3ZRCB 2IHCA 4CRHA 4CP3A 1T1DA 4U2NA 1EXBE 3M52A 2I2RA 3HTMA 5HZGC 4W9FB 4WQOC 1A68A 2A79B 3ZTCB 5H7HA 5FTAA 2OVPA 2YY9A 5A6RA 4W9JB 1R28A 4JTDB 3BIMA 4U2MA 4I6JC 4W9HB 1VCBB 2FNJC 3MKSA 4B9KB 1LQBB 4BKTB 5BXDA 4ZOUA 4JGHC 3M4TA 1QDWA 3C6OA 2MA9C 1DSXA 2ASTA 4HXIA 3OGLA 5BO4C 4EOZA 5LLIB 5EUPA 2P1OA 1NEXA 2C9WC 1HV2A 3M8VA 2NZ0B 3I3NA 3ZTDB 5BXHA 1NN7A 4N9F5 3HVEB 4W9EB 4UYIA 4CXIA 1EODA 3E4UA 3HU6A 4W9IB 1FS1B 4U77A 4APFA 2P1QA 4J8ZA 4UIJA 3HQIA 3ZRFB 3OHVA 3C6PA 3GA1A 5H7GA 1BUOA 4W9HH 3B84A 1CS3A 1P22B 4B9KE 4YY8A 2IF5A 1S1GA 2OVRA 2OVQA 4AP2A 2P1MA 5DAFA 2P1NA 4BKSB 2E31B 1EOFA 2Q81A 2VPKA 3DCGB 4AWJB 4CXJA 4JTCB 3DRZA 2E32B 2PPIA 4JTAB 2Z8HA 3L2OA 3OHUA 3ZUNB 5HYWB 3M5BA 2P1PA 3ZNGB 2ASSA 4AJYC 4CXTA 3HVEA 1FS2B 2R9RB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IBK A;  3LNM B;  3V7D A;  2NN2 A;  4B95 B;  3OGK A;  4W9C B;  4W9L B;  3ZKJ B;  4W9D B;  2JZ3 C;  3KVT A;  1LM8 C;  1EOE A;  3C6N A;  5A15 A;  5DAD A;  3OGM A;  3WSO B;  1QDV A;  4W9G B;  1FQV B;  1R29 A;  3LUT B;  4W9K B;  5JH5 B;  5BXB A;  1LDK D;  3FKC A;  3LBZ A;  2VKP A;  2IZV C;  1R2B A;  4BGC A;  3ZRC B;  2IHC A;  4CRH A;  4CP3 A;  1T1D A;  4U2N A;  1EXB E;  3M52 A;  2I2R A;  3HTM A;  5HZG C;  4W9F B;  4WQO C;  1A68 A;  2A79 B;  3ZTC B;  5H7H A;  5FTA A;  2OVP A;  2YY9 A;  5A6R A;  4W9J B;  1R28 A;  4JTD B;  3BIM A;  4U2M A;  4I6J C;  4W9H B;  1VCB B;  2FNJ C;  3MKS A;  4B9K B;  1LQB B;  4BKT B;  5BXD A;  4ZOU A;  4JGH C;  3M4T A;  1QDW A;  3C6O A;  2MA9 C;  1DSX A;  2AST A;  4HXI A;  3OGL A;  5BO4 C;  4EOZ A;  5LLI B;  5EUP A;  2P1O A;  1NEX A;  2C9W C;  1HV2 A;  3M8V A;  2NZ0 B;  3I3N A;  3ZTD B;  5BXH A;  1NN7 A;  4N9F 5;  3HVE B;  4W9E B;  4UYI A;  4CXI A;  1EOD A;  3E4U A;  3HU6 A;  4W9I B;  1FS1 B;  4U77 A;  4APF A;  2P1Q A;  4J8Z A;  4UIJ A;  3HQI A;  3ZRF B;  3OHV A;  3C6P A;  3GA1 A;  5H7G A;  1BUO A;  4W9H H;  3B84 A;  1CS3 A;  1P22 B;  4B9K E;  2IF5 A;  1S1G A;  2OVR A;  2OVQ A;  4AP2 A;  2P1M A;  5DAF A;  2P1N A;  4BKS B;  2E31 B;  1EOF A;  2Q81 A;  2VPK A;  3DCG B;  4AWJ B;  4CXJ A;  4JTC B;  3DRZ A;  2E32 B;  2PPI A;  4JTA B;  2Z8H A;  3L2O A;  3OHU A;  3ZUN B;  5HYW B;  3M5B A;  2P1P A;  3ZNG B;  2ASS A;  4AJY C;  4CXT A;  3HVE A;  1FS2 B;  2R9R B; 
#chains in the Genus database with same CATH topology
 5IBK A;  3LNM B;  3V7D A;  2NN2 A;  4B95 B;  3OGK A;  4W9C B;  4W9L B;  3DRX A;  3ZKJ B;  4W9D B;  2JZ3 C;  3KVT A;  1LM8 C;  1EOE A;  3C6N A;  5A15 A;  5DAD A;  3OGM A;  3WSO B;  4ZGC A;  1QDV A;  4W9G B;  1FQV B;  1R29 A;  3LUT B;  4W9K B;  3DRY A;  5JH5 B;  5BXB A;  1LDK D;  3FKC A;  3LBZ A;  2VKP A;  2IZV C;  1R2B A;  4BGC A;  3ZRC B;  2IHC A;  4CRH A;  4CP3 A;  1T1D A;  4U2N A;  1EXB E;  3M52 A;  2I2R A;  3HTM A;  5HZG C;  4W9F B;  4WQO C;  1A68 A;  2A79 B;  3ZTC B;  5H7H A;  5FTA A;  2OVP A;  2YY9 A;  5A6R A;  4W9J B;  1R28 A;  4JTD B;  3BIM A;  4U2M A;  4I6J C;  4W9H B;  1VCB B;  2FNJ C;  3MKS A;  4B9K B;  1LQB B;  4BKT B;  5BXD A;  4ZOU A;  4JGH C;  3M4T A;  1QDW A;  3C6O A;  2MA9 C;  1DSX A;  2AST A;  4HXI A;  3OGL A;  5BO4 C;  4EOZ A;  5LLI B;  5EUP A;  2P1O A;  1NEX A;  2C9W C;  1HV2 A;  3M8V A;  2NZ0 B;  3I3N A;  3ZTD B;  5BXH A;  1NN7 A;  4N9F 5;  3HVE B;  4W9E B;  4UYI A;  4CXI A;  1EOD A;  3E4U A;  3HU6 A;  4W9I B;  1FS1 B;  4U77 A;  4APF A;  2P1Q A;  4J8Z A;  4UIJ A;  3HQI A;  3ZRF B;  3OHV A;  3C6P A;  3GA1 A;  5H7G A;  1BUO A;  4W9H H;  3B84 A;  1CS3 A;  1P22 B;  4B9K E;  4YY8 A;  2IF5 A;  1S1G A;  2OVR A;  2OVQ A;  4AP2 A;  2P1M A;  5DAF A;  2P1N A;  4BKS B;  2E31 B;  1EOF A;  2Q81 A;  2VPK A;  3DCG B;  4AWJ B;  4CXJ A;  4JTC B;  3DRZ A;  2E32 B;  2PPI A;  4JTA B;  2Z8H A;  3L2O A;  3OHU A;  3ZUN B;  5HYW B;  3M5B A;  2P1P A;  3ZNG B;  2ASS A;  4AJY C;  4CXT A;  3HVE A;  1FS2 B;  2R9R B; 
#chains in the Genus database with same CATH homology
 5IBK A;  3LNM B;  3V7D A;  2NN2 A;  4B95 B;  3OGK A;  4W9C B;  4W9L B;  3DRX A;  3ZKJ B;  4W9D B;  2JZ3 C;  3KVT A;  1LM8 C;  1EOE A;  3C6N A;  5A15 A;  5DAD A;  3OGM A;  3WSO B;  4ZGC A;  1QDV A;  4W9G B;  1FQV B;  1R29 A;  3LUT B;  4W9K B;  3DRY A;  5JH5 B;  5BXB A;  1LDK D;  3FKC A;  3LBZ A;  2VKP A;  2IZV C;  1R2B A;  4BGC A;  3ZRC B;  2IHC A;  4CRH A;  4CP3 A;  1T1D A;  4U2N A;  1EXB E;  3M52 A;  2I2R A;  3HTM A;  5HZG C;  4W9F B;  4WQO C;  1A68 A;  2A79 B;  3ZTC B;  5H7H A;  5FTA A;  2OVP A;  2YY9 A;  5A6R A;  4W9J B;  1R28 A;  4JTD B;  3BIM A;  4U2M A;  4I6J C;  4W9H B;  1VCB B;  2FNJ C;  3MKS A;  4B9K B;  1LQB B;  4BKT B;  5BXD A;  4ZOU A;  4JGH C;  3M4T A;  1QDW A;  3C6O A;  2MA9 C;  1DSX A;  2AST A;  4HXI A;  3OGL A;  5BO4 C;  4EOZ A;  5LLI B;  5EUP A;  2P1O A;  1NEX A;  2C9W C;  1HV2 A;  3M8V A;  2NZ0 B;  3I3N A;  3ZTD B;  5BXH A;  1NN7 A;  4N9F 5;  3HVE B;  4W9E B;  4UYI A;  4CXI A;  1EOD A;  3E4U A;  3HU6 A;  4W9I B;  1FS1 B;  4U77 A;  4APF A;  2P1Q A;  4J8Z A;  4UIJ A;  3HQI A;  3ZRF B;  3OHV A;  3C6P A;  3GA1 A;  5H7G A;  1BUO A;  4W9H H;  3B84 A;  1CS3 A;  1P22 B;  4B9K E;  4YY8 A;  2IF5 A;  1S1G A;  2OVR A;  2OVQ A;  4AP2 A;  2P1M A;  5DAF A;  2P1N A;  4BKS B;  2E31 B;  1EOF A;  2Q81 A;  2VPK A;  3DCG B;  4AWJ B;  4CXJ A;  4JTC B;  3DRZ A;  2E32 B;  2PPI A;  4JTA B;  2Z8H A;  3L2O A;  3OHU A;  3ZUN B;  5HYW B;  3M5B A;  2P1P A;  3ZNG B;  2ASS A;  4AJY C;  4CXT A;  3HVE A;  1FS2 B;  2R9R B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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