4CXT | Genus

Total Genus 40

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	40
sequence length	132
structure length	132
Chain Sequence	NRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACADFLVQQLD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__396914330597568__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__396914330597568__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4CXT/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__396914330597568__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"396914330597568","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4CXT/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__396914330597568__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/file/5d03a50ec73955f4e0c6ba0c/pdb.gz

Viewer cachePut https://genus.fuw.edu.pl/file/5d03a50ec73955f4e0c6ba0c/pdb.gz

FileManager.getAtomSetCollectionFromFile(/file/5d03a50ec73955f4e0c6ba0c/pdb.gz)

loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d03a50ec73955f4e0c6ba0c/pdb.gz): 565 ms

reading 132 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

132 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 18 ms

Adding embedded #jmolscript: select ({0:131});backbone only;select *;

platformSpeed = 8

cartoonsFancy = true

sheetSmoothing = 1.0

traceAlpha = true

loadScript /static/js/j2s/core/corescriptcmd.z.js

specularPower = 9

ambientPercent = 20

antialiasDisplay = true

Script completed

Jmol script terminated

loadScript /static/js/j2s/J/g3d/HermiteRenderer.js

loadScript /static/js/j2s/J/renderbio/BioMeshRenderer.js

loadScript /static/js/j2s/J/render/MeshRenderer.js

loadScript /static/js/j2s/J/shape/Mesh.js

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo. pubmed doi rcsb
molecule keywords	KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
total genus	40
structure length	132
sequence length	132
ec nomenclature
pdb deposition date	2014-04-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00651	BTB	BTB/POZ domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	4cxtA00

1LQBB 4N9F5 4AJYC 3B84A 1QDVA 4CXIA 2E32B 3I3NA 4WQOC 1NEXA 3HVEA 4CRHA 1EODA 4W9DB 5FTAA 3M8VA 3L2OA 2P1MA 1LDKD 4B9KE 4W9FB 5A6RA 1QDWA 4CXTA 1EOEA 4UIJA 5IBKA 5H7GA 3KVTA 2VKPA 2IF5A 5BXDA 2OVPA 4W9LB 1A68A 4I6JC 1R2BA 4ZOUA 2I2RA 1P22B 4W9CB 3ZRCB 3OGMA 4J8ZA 5EUPA 5LLIB 1NN7A 3M4TA 5A15A 4AP2A 3OHUA 1EOFA 3M52A 3E4UA 4BGCA 4APFA 4JTDB 4JTCB 4W9HH 3LBZA 5JH5B 3BIMA 3OGKA 4EOZA 2YY9A 2E31B 2ASSA 3LNMB 1FS2B 4CXJA 3DCGB 5DAFA 1R29A 2FNJC 4U77A 1S1GA 2VPKA 4CP3A 3C6NA 3ZRFB 2A79B 5DADA 4U2MA 2ASTA 4W9GB 5H7HA 3ZUNB 1T1DA 3HU6A 3C6OA 3OGLA 3ZKJB 3ZTCB 1R28A 4JGHC 3HVEB 4W9IB 1CS3A 2P1PA 5BO4C 2P1QA 1DSXA 3OHVA 1FQVB 3M5BA 5BXHA 3HQIA 4W9JB 3LUTB 4W9HB 1LM8C 3DRZA 2R9RB 3C6PA 2C9WC 2P1OA 4B95B 1VCBB 3MKSA 2OVRA 2NZ0B 2OVQA 4W9KB 5HZGC 3FKCA 3ZNGB 5BXBA 2Q81A 4U2NA 3WSOB 4AWJB 2Z8HA 4BKSB 3V7DA 2MA9C 3GA1A 5HYWB 1BUOA 2NN2A 2PPIA 2JZ3C 3HTMA 1EXBE 4B9KB 4JTAB 2P1NA 4HXIA 4UYIA 1FS1B 4BKTB 1HV2A 3ZTDB 2IHCA 2IZVC 4W9EB
chains in the Genus database with same CATH superfamily

1LQBB 4YY8A 4N9F5 4AJYC 3B84A 1QDVA 4CXIA 2E32B 3I3NA 4WQOC 1NEXA 3HVEA 4CRHA 1EODA 4W9DB 5FTAA 3M8VA 3L2OA 2P1MA 1LDKD 4B9KE 4W9FB 5A6RA 1QDWA 4CXTA 1EOEA 4UIJA 5IBKA 5H7GA 3KVTA 3DRYA 2VKPA 2IF5A 5BXDA 2OVPA 4W9LB 1A68A 4I6JC 1R2BA 4ZOUA 2I2RA 1P22B 4W9CB 3ZRCB 3OGMA 4J8ZA 5EUPA 5LLIB 1NN7A 3M4TA 5A15A 4AP2A 3OHUA 1EOFA 3M52A 3E4UA 4BGCA 4APFA 4JTDB 4JTCB 4W9HH 3LBZA 5JH5B 3BIMA 3OGKA 4EOZA 2YY9A 2E31B 2ASSA 3LNMB 1FS2B 4CXJA 3DCGB 5DAFA 1R29A 2FNJC 4U77A 1S1GA 2VPKA 4CP3A 3C6NA 3ZRFB 2A79B 5DADA 4U2MA 2ASTA 4W9GB 5H7HA 3ZUNB 1T1DA 3HU6A 3C6OA 3OGLA 3ZKJB 3ZTCB 1R28A 4JGHC 3HVEB 4W9IB 1CS3A 2P1PA 5BO4C 2P1QA 3DRXA 1DSXA 3OHVA 1FQVB 3M5BA 5BXHA 3HQIA 4W9JB 3LUTB 4W9HB 1LM8C 3DRZA 2R9RB 3C6PA 2C9WC 2P1OA 4B95B 1VCBB 3MKSA 2OVRA 2NZ0B 2OVQA 4W9KB 5HZGC 3FKCA 3ZNGB 5BXBA 2Q81A 4U2NA 3WSOB 4AWJB 2Z8HA 4BKSB 3V7DA 2MA9C 3GA1A 5HYWB 1BUOA 2NN2A 2PPIA 2JZ3C 3HTMA 1EXBE 4B9KB 4JTAB 2P1NA 4HXIA 4UYIA 1FS1B 4BKTB 1HV2A 3ZTDB 2IHCA 4ZGCA 2IZVC 4W9EB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1LQB B;  4N9F 5;  4AJY C;  3B84 A;  1QDV A;  4CXI A;  2E32 B;  3I3N A;  4WQO C;  1NEX A;  3HVE A;  4CRH A;  1EOD A;  4W9D B;  5FTA A;  3M8V A;  3L2O A;  2P1M A;  1LDK D;  4B9K E;  4W9F B;  5A6R A;  1QDW A;  4CXT A;  1EOE A;  4UIJ A;  5IBK A;  5H7G A;  3KVT A;  2VKP A;  2IF5 A;  5BXD A;  2OVP A;  4W9L B;  1A68 A;  4I6J C;  1R2B A;  4ZOU A;  2I2R A;  1P22 B;  4W9C B;  3ZRC B;  3OGM A;  4J8Z A;  5EUP A;  5LLI B;  1NN7 A;  3M4T A;  5A15 A;  4AP2 A;  3OHU A;  1EOF A;  3M52 A;  3E4U A;  4BGC A;  4APF A;  4JTD B;  4JTC B;  4W9H H;  3LBZ A;  5JH5 B;  3BIM A;  3OGK A;  4EOZ A;  2YY9 A;  2E31 B;  2ASS A;  3LNM B;  1FS2 B;  4CXJ A;  3DCG B;  5DAF A;  1R29 A;  2FNJ C;  4U77 A;  1S1G A;  2VPK A;  4CP3 A;  3C6N A;  3ZRF B;  2A79 B;  5DAD A;  4U2M A;  2AST A;  4W9G B;  5H7H A;  3ZUN B;  1T1D A;  3HU6 A;  3C6O A;  3OGL A;  3ZKJ B;  3ZTC B;  1R28 A;  4JGH C;  3HVE B;  4W9I B;  1CS3 A;  2P1P A;  5BO4 C;  2P1Q A;  1DSX A;  3OHV A;  1FQV B;  3M5B A;  5BXH A;  3HQI A;  4W9J B;  3LUT B;  4W9H B;  1LM8 C;  3DRZ A;  2R9R B;  3C6P A;  2C9W C;  2P1O A;  4B95 B;  1VCB B;  3MKS A;  2OVR A;  2NZ0 B;  2OVQ A;  4W9K B;  5HZG C;  3FKC A;  3ZNG B;  5BXB A;  2Q81 A;  4U2N A;  3WSO B;  4AWJ B;  2Z8H A;  4BKS B;  3V7D A;  2MA9 C;  3GA1 A;  5HYW B;  1BUO A;  2NN2 A;  2PPI A;  2JZ3 C;  3HTM A;  1EXB E;  4B9K B;  4JTA B;  2P1N A;  4HXI A;  4UYI A;  1FS1 B;  4BKT B;  1HV2 A;  3ZTD B;  2IHC A;  2IZV C;  4W9E B; 
#chains in the Genus database with same CATH topology
 1LQB B;  4YY8 A;  4N9F 5;  4AJY C;  3B84 A;  1QDV A;  4CXI A;  2E32 B;  3I3N A;  4WQO C;  1NEX A;  3HVE A;  4CRH A;  1EOD A;  4W9D B;  5FTA A;  3M8V A;  3L2O A;  2P1M A;  1LDK D;  4B9K E;  4W9F B;  5A6R A;  1QDW A;  4CXT A;  1EOE A;  4UIJ A;  5IBK A;  5H7G A;  3KVT A;  3DRY A;  2VKP A;  2IF5 A;  5BXD A;  2OVP A;  4W9L B;  1A68 A;  4I6J C;  1R2B A;  4ZOU A;  2I2R A;  1P22 B;  4W9C B;  3ZRC B;  3OGM A;  4J8Z A;  5EUP A;  5LLI B;  1NN7 A;  3M4T A;  5A15 A;  4AP2 A;  3OHU A;  1EOF A;  3M52 A;  3E4U A;  4BGC A;  4APF A;  4JTD B;  4JTC B;  4W9H H;  3LBZ A;  5JH5 B;  3BIM A;  3OGK A;  4EOZ A;  2YY9 A;  2E31 B;  2ASS A;  3LNM B;  1FS2 B;  4CXJ A;  3DCG B;  5DAF A;  1R29 A;  2FNJ C;  4U77 A;  1S1G A;  2VPK A;  4CP3 A;  3C6N A;  3ZRF B;  2A79 B;  5DAD A;  4U2M A;  2AST A;  4W9G B;  5H7H A;  3ZUN B;  1T1D A;  3HU6 A;  3C6O A;  3OGL A;  3ZKJ B;  3ZTC B;  1R28 A;  4JGH C;  3HVE B;  4W9I B;  1CS3 A;  2P1P A;  5BO4 C;  2P1Q A;  3DRX A;  1DSX A;  3OHV A;  1FQV B;  3M5B A;  5BXH A;  3HQI A;  4W9J B;  3LUT B;  4W9H B;  1LM8 C;  3DRZ A;  2R9R B;  3C6P A;  2C9W C;  2P1O A;  4B95 B;  1VCB B;  3MKS A;  2OVR A;  2NZ0 B;  2OVQ A;  4W9K B;  5HZG C;  3FKC A;  3ZNG B;  5BXB A;  2Q81 A;  4U2N A;  3WSO B;  4AWJ B;  2Z8H A;  4BKS B;  3V7D A;  2MA9 C;  3GA1 A;  5HYW B;  1BUO A;  2NN2 A;  2PPI A;  2JZ3 C;  3HTM A;  1EXB E;  4B9K B;  4JTA B;  2P1N A;  4HXI A;  4UYI A;  1FS1 B;  4BKT B;  1HV2 A;  3ZTD B;  2IHC A;  4ZGC A;  2IZV C;  4W9E B; 
#chains in the Genus database with same CATH homology
 1LQB B;  4YY8 A;  4N9F 5;  4AJY C;  3B84 A;  1QDV A;  4CXI A;  2E32 B;  3I3N A;  4WQO C;  1NEX A;  3HVE A;  4CRH A;  1EOD A;  4W9D B;  5FTA A;  3M8V A;  3L2O A;  2P1M A;  1LDK D;  4B9K E;  4W9F B;  5A6R A;  1QDW A;  4CXT A;  1EOE A;  4UIJ A;  5IBK A;  5H7G A;  3KVT A;  3DRY A;  2VKP A;  2IF5 A;  5BXD A;  2OVP A;  4W9L B;  1A68 A;  4I6J C;  1R2B A;  4ZOU A;  2I2R A;  1P22 B;  4W9C B;  3ZRC B;  3OGM A;  4J8Z A;  5EUP A;  5LLI B;  1NN7 A;  3M4T A;  5A15 A;  4AP2 A;  3OHU A;  1EOF A;  3M52 A;  3E4U A;  4BGC A;  4APF A;  4JTD B;  4JTC B;  4W9H H;  3LBZ A;  5JH5 B;  3BIM A;  3OGK A;  4EOZ A;  2YY9 A;  2E31 B;  2ASS A;  3LNM B;  1FS2 B;  4CXJ A;  3DCG B;  5DAF A;  1R29 A;  2FNJ C;  4U77 A;  1S1G A;  2VPK A;  4CP3 A;  3C6N A;  3ZRF B;  2A79 B;  5DAD A;  4U2M A;  2AST A;  4W9G B;  5H7H A;  3ZUN B;  1T1D A;  3HU6 A;  3C6O A;  3OGL A;  3ZKJ B;  3ZTC B;  1R28 A;  4JGH C;  3HVE B;  4W9I B;  1CS3 A;  2P1P A;  5BO4 C;  2P1Q A;  3DRX A;  1DSX A;  3OHV A;  1FQV B;  3M5B A;  5BXH A;  3HQI A;  4W9J B;  3LUT B;  4W9H B;  1LM8 C;  3DRZ A;  2R9R B;  3C6P A;  2C9W C;  2P1O A;  4B95 B;  1VCB B;  3MKS A;  2OVR A;  2NZ0 B;  2OVQ A;  4W9K B;  5HZG C;  3FKC A;  3ZNG B;  5BXB A;  2Q81 A;  4U2N A;  3WSO B;  4AWJ B;  2Z8H A;  4BKS B;  3V7D A;  2MA9 C;  3GA1 A;  5HYW B;  1BUO A;  2NN2 A;  2PPI A;  2JZ3 C;  3HTM A;  1EXB E;  4B9K B;  4JTA B;  2P1N A;  4HXI A;  4UYI A;  1FS1 B;  4BKT B;  1HV2 A;  3ZTD B;  2IHC A;  4ZGC A;  2IZV C;  4W9E B;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4CXTA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations