4EOZA

Crystal structure of the spop btb domain complexed with the cul3 n-terminal domain
Total Genus 35

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
114
structure length
114
Chain Sequence
VKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Protein binding
source organism Homo sapiens
publication title Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.
pubmed doi rcsb
molecule keywords Speckle-type POZ protein
total genus 35
structure length 114
sequence length 114
chains with identical sequence C
ec nomenclature
pdb deposition date 2012-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 4eozA00
4ZOUA 4APFA 4J8ZA 5LLIB 2ASTA 3OGLA 4UYIA 3MKSA 1EOFA 2P1OA 5H7GA 4CP3A 1FS2B 3DCGB 2FNJC 1EXBE 3ZNGB 5EUPA 4B95B 3ZRCB 3GA1A 4WQOC 2R9RB 2P1QA 4JTDB 4CXIA 4AJYC 2IF5A 2PPIA 4U2MA 4B9KE 3I3NA 1BUOA 2E32B 5HZGC 2E31B 3E4UA 4W9KB 3B84A 2I2RA 4AWJB 3LNMB 3OGMA 4I6JC 4W9IB 4EOZA 3OHUA 1VCBB 4AP2A 3HVEB 4U2NA 1CS3A 3FKCA 1FQVB 5A15A 1T1DA 4W9LB 1P22B 5BXHA 4UIJA 1R29A 2OVRA 5A6RA 2P1NA 3ZTCB 1R28A 2A79B 5BXBA 4W9HB 3L2OA 2P1PA 3C6PA 3KVTA 2Q81A 2JZ3C 4CXTA 2OVPA 3ZRFB 2YY9A 3HTMA 5JH5B 1DSXA 5DAFA 4N9F5 2ASSA 1LQBB 1EOEA 1HV2A 1QDWA 1NEXA 4BGCA 4W9FB 3LBZA 4CRHA 4U77A 1R2BA 1NN7A 2Z8HA 3HVEA 3M52A 4JGHC 3WSOB 2C9WC 4JTAB 4BKSB 3DRZA 4HXIA 2MA9C 2VPKA 5HYWB 4W9JB 4W9CB 5DADA 4CXJA 1FS1B 1A68A 4BKTB 1QDVA 4W9EB 3HU6A 3HQIA 1LM8C 1S1GA 2NN2A 3OHVA 1EODA 3LUTB 3BIMA 3C6OA 5FTAA 4JTCB 5BO4C 3C6NA 2OVQA 4W9DB 3ZKJB 2IZVC 3ZTDB 4W9HH 5H7HA 3V7DA 4W9GB 2IHCA 2NZ0B 1LDKD 5IBKA 2P1MA 3ZUNB 4B9KB 5BXDA 3M8VA 2VKPA 3M5BA 3OGKA 3M4TA
chains in the Genus database with same CATH superfamily
4ZOUA 4APFA 4J8ZA 5LLIB 2ASTA 3OGLA 4UYIA 3MKSA 1EOFA 2P1OA 5H7GA 4CP3A 1FS2B 3DCGB 2FNJC 1EXBE 3ZNGB 3DRXA 5EUPA 4B95B 3ZRCB 3GA1A 4WQOC 2R9RB 2P1QA 4JTDB 4CXIA 4AJYC 2IF5A 2PPIA 4U2MA 4B9KE 3I3NA 1BUOA 2E32B 5HZGC 2E31B 3E4UA 4W9KB 3B84A 2I2RA 4AWJB 3LNMB 3OGMA 4I6JC 4W9IB 4EOZA 3OHUA 1VCBB 4AP2A 3HVEB 4U2NA 1CS3A 3FKCA 1FQVB 5A15A 1T1DA 4W9LB 1P22B 5BXHA 4UIJA 1R29A 2OVRA 5A6RA 4ZGCA 2P1NA 3ZTCB 1R28A 2A79B 5BXBA 4W9HB 3L2OA 2P1PA 3C6PA 3KVTA 2Q81A 2JZ3C 4CXTA 2OVPA 3ZRFB 2YY9A 3HTMA 5JH5B 3DRYA 1DSXA 5DAFA 4N9F5 2ASSA 1LQBB 1EOEA 1HV2A 1QDWA 1NEXA 4BGCA 4W9FB 3LBZA 4CRHA 4U77A 1R2BA 1NN7A 2Z8HA 3HVEA 3M52A 4JGHC 3WSOB 2C9WC 4JTAB 4BKSB 3DRZA 4HXIA 4YY8A 2MA9C 2VPKA 5HYWB 4W9JB 4W9CB 5DADA 4CXJA 1FS1B 1A68A 4BKTB 1QDVA 4W9EB 3HU6A 3HQIA 1LM8C 1S1GA 2NN2A 3OHVA 1EODA 3LUTB 3BIMA 3C6OA 5FTAA 4JTCB 5BO4C 3C6NA 2OVQA 4W9DB 3ZKJB 2IZVC 3ZTDB 4W9HH 5H7HA 3V7DA 4W9GB 2IHCA 2NZ0B 1LDKD 5IBKA 2P1MA 3ZUNB 4B9KB 5BXDA 3M8VA 2VKPA 3M5BA 3OGKA 3M4TA
chains in the Genus database with same CATH topology
4ZOUA 4APFA 4J8ZA 5LLIB 2ASTA 3OGLA 4UYIA 3MKSA 1EOFA 2P1OA 5H7GA 4CP3A 1FS2B 3DCGB 2FNJC 1EXBE 3ZNGB 3DRXA 5EUPA 4B95B 3ZRCB 3GA1A 4WQOC 2R9RB 2P1QA 4JTDB 4CXIA 4AJYC 2IF5A 2PPIA 4U2MA 4B9KE 3I3NA 1BUOA 2E32B 5HZGC 2E31B 3E4UA 4W9KB 3B84A 2I2RA 4AWJB 3LNMB 3OGMA 4I6JC 4W9IB 4EOZA 3OHUA 1VCBB 4AP2A 3HVEB 4U2NA 1CS3A 3FKCA 1FQVB 5A15A 1T1DA 4W9LB 1P22B 5BXHA 4UIJA 1R29A 2OVRA 5A6RA 4ZGCA 2P1NA 3ZTCB 1R28A 2A79B 5BXBA 4W9HB 3L2OA 2P1PA 3C6PA 3KVTA 2Q81A 2JZ3C 4CXTA 2OVPA 3ZRFB 2YY9A 3HTMA 5JH5B 3DRYA 1DSXA 5DAFA 4N9F5 2ASSA 1LQBB 1EOEA 1HV2A 1QDWA 1NEXA 4BGCA 4W9FB 3LBZA 4CRHA 4U77A 1R2BA 1NN7A 2Z8HA 3HVEA 3M52A 4JGHC 3WSOB 2C9WC 4JTAB 4BKSB 3DRZA 4HXIA 4YY8A 2MA9C 2VPKA 5HYWB 4W9JB 4W9CB 5DADA 4CXJA 1FS1B 1A68A 4BKTB 1QDVA 4W9EB 3HU6A 3HQIA 1LM8C 1S1GA 2NN2A 3OHVA 1EODA 3LUTB 3BIMA 3C6OA 5FTAA 4JTCB 5BO4C 3C6NA 2OVQA 4W9DB 3ZKJB 2IZVC 3ZTDB 4W9HH 5H7HA 3V7DA 4W9GB 2IHCA 2NZ0B 1LDKD 5IBKA 2P1MA 3ZUNB 4B9KB 5BXDA 3M8VA 2VKPA 3M5BA 3OGKA 3M4TA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4ZOU A;  4APF A;  4J8Z A;  5LLI B;  2AST A;  3OGL A;  4UYI A;  3MKS A;  1EOF A;  2P1O A;  5H7G A;  4CP3 A;  1FS2 B;  3DCG B;  2FNJ C;  1EXB E;  3ZNG B;  5EUP A;  4B95 B;  3ZRC B;  3GA1 A;  4WQO C;  2R9R B;  2P1Q A;  4JTD B;  4CXI A;  4AJY C;  2IF5 A;  2PPI A;  4U2M A;  4B9K E;  3I3N A;  1BUO A;  2E32 B;  5HZG C;  2E31 B;  3E4U A;  4W9K B;  3B84 A;  2I2R A;  4AWJ B;  3LNM B;  3OGM A;  4I6J C;  4W9I B;  4EOZ A;  3OHU A;  1VCB B;  4AP2 A;  3HVE B;  4U2N A;  1CS3 A;  3FKC A;  1FQV B;  5A15 A;  1T1D A;  4W9L B;  1P22 B;  5BXH A;  4UIJ A;  1R29 A;  2OVR A;  5A6R A;  2P1N A;  3ZTC B;  1R28 A;  2A79 B;  5BXB A;  4W9H B;  3L2O A;  2P1P A;  3C6P A;  3KVT A;  2Q81 A;  2JZ3 C;  4CXT A;  2OVP A;  3ZRF B;  2YY9 A;  3HTM A;  5JH5 B;  1DSX A;  5DAF A;  4N9F 5;  2ASS A;  1LQB B;  1EOE A;  1HV2 A;  1QDW A;  1NEX A;  4BGC A;  4W9F B;  3LBZ A;  4CRH A;  4U77 A;  1R2B A;  1NN7 A;  2Z8H A;  3HVE A;  3M52 A;  4JGH C;  3WSO B;  2C9W C;  4JTA B;  4BKS B;  3DRZ A;  4HXI A;  2MA9 C;  2VPK A;  5HYW B;  4W9J B;  4W9C B;  5DAD A;  4CXJ A;  1FS1 B;  1A68 A;  4BKT B;  1QDV A;  4W9E B;  3HU6 A;  3HQI A;  1LM8 C;  1S1G A;  2NN2 A;  3OHV A;  1EOD A;  3LUT B;  3BIM A;  3C6O A;  5FTA A;  4JTC B;  5BO4 C;  3C6N A;  2OVQ A;  4W9D B;  3ZKJ B;  2IZV C;  3ZTD B;  4W9H H;  5H7H A;  3V7D A;  4W9G B;  2IHC A;  2NZ0 B;  1LDK D;  5IBK A;  2P1M A;  3ZUN B;  4B9K B;  5BXD A;  3M8V A;  2VKP A;  3M5B A;  3OGK A;  3M4T A; 
#chains in the Genus database with same CATH topology
 4ZOU A;  4APF A;  4J8Z A;  5LLI B;  2AST A;  3OGL A;  4UYI A;  3MKS A;  1EOF A;  2P1O A;  5H7G A;  4CP3 A;  1FS2 B;  3DCG B;  2FNJ C;  1EXB E;  3ZNG B;  3DRX A;  5EUP A;  4B95 B;  3ZRC B;  3GA1 A;  4WQO C;  2R9R B;  2P1Q A;  4JTD B;  4CXI A;  4AJY C;  2IF5 A;  2PPI A;  4U2M A;  4B9K E;  3I3N A;  1BUO A;  2E32 B;  5HZG C;  2E31 B;  3E4U A;  4W9K B;  3B84 A;  2I2R A;  4AWJ B;  3LNM B;  3OGM A;  4I6J C;  4W9I B;  4EOZ A;  3OHU A;  1VCB B;  4AP2 A;  3HVE B;  4U2N A;  1CS3 A;  3FKC A;  1FQV B;  5A15 A;  1T1D A;  4W9L B;  1P22 B;  5BXH A;  4UIJ A;  1R29 A;  2OVR A;  5A6R A;  4ZGC A;  2P1N A;  3ZTC B;  1R28 A;  2A79 B;  5BXB A;  4W9H B;  3L2O A;  2P1P A;  3C6P A;  3KVT A;  2Q81 A;  2JZ3 C;  4CXT A;  2OVP A;  3ZRF B;  2YY9 A;  3HTM A;  5JH5 B;  3DRY A;  1DSX A;  5DAF A;  4N9F 5;  2ASS A;  1LQB B;  1EOE A;  1HV2 A;  1QDW A;  1NEX A;  4BGC A;  4W9F B;  3LBZ A;  4CRH A;  4U77 A;  1R2B A;  1NN7 A;  2Z8H A;  3HVE A;  3M52 A;  4JGH C;  3WSO B;  2C9W C;  4JTA B;  4BKS B;  3DRZ A;  4HXI A;  4YY8 A;  2MA9 C;  2VPK A;  5HYW B;  4W9J B;  4W9C B;  5DAD A;  4CXJ A;  1FS1 B;  1A68 A;  4BKT B;  1QDV A;  4W9E B;  3HU6 A;  3HQI A;  1LM8 C;  1S1G A;  2NN2 A;  3OHV A;  1EOD A;  3LUT B;  3BIM A;  3C6O A;  5FTA A;  4JTC B;  5BO4 C;  3C6N A;  2OVQ A;  4W9D B;  3ZKJ B;  2IZV C;  3ZTD B;  4W9H H;  5H7H A;  3V7D A;  4W9G B;  2IHC A;  2NZ0 B;  1LDK D;  5IBK A;  2P1M A;  3ZUN B;  4B9K B;  5BXD A;  3M8V A;  2VKP A;  3M5B A;  3OGK A;  3M4T A; 
#chains in the Genus database with same CATH homology
 4ZOU A;  4APF A;  4J8Z A;  5LLI B;  2AST A;  3OGL A;  4UYI A;  3MKS A;  1EOF A;  2P1O A;  5H7G A;  4CP3 A;  1FS2 B;  3DCG B;  2FNJ C;  1EXB E;  3ZNG B;  3DRX A;  5EUP A;  4B95 B;  3ZRC B;  3GA1 A;  4WQO C;  2R9R B;  2P1Q A;  4JTD B;  4CXI A;  4AJY C;  2IF5 A;  2PPI A;  4U2M A;  4B9K E;  3I3N A;  1BUO A;  2E32 B;  5HZG C;  2E31 B;  3E4U A;  4W9K B;  3B84 A;  2I2R A;  4AWJ B;  3LNM B;  3OGM A;  4I6J C;  4W9I B;  4EOZ A;  3OHU A;  1VCB B;  4AP2 A;  3HVE B;  4U2N A;  1CS3 A;  3FKC A;  1FQV B;  5A15 A;  1T1D A;  4W9L B;  1P22 B;  5BXH A;  4UIJ A;  1R29 A;  2OVR A;  5A6R A;  4ZGC A;  2P1N A;  3ZTC B;  1R28 A;  2A79 B;  5BXB A;  4W9H B;  3L2O A;  2P1P A;  3C6P A;  3KVT A;  2Q81 A;  2JZ3 C;  4CXT A;  2OVP A;  3ZRF B;  2YY9 A;  3HTM A;  5JH5 B;  3DRY A;  1DSX A;  5DAF A;  4N9F 5;  2ASS A;  1LQB B;  1EOE A;  1HV2 A;  1QDW A;  1NEX A;  4BGC A;  4W9F B;  3LBZ A;  4CRH A;  4U77 A;  1R2B A;  1NN7 A;  2Z8H A;  3HVE A;  3M52 A;  4JGH C;  3WSO B;  2C9W C;  4JTA B;  4BKS B;  3DRZ A;  4HXI A;  4YY8 A;  2MA9 C;  2VPK A;  5HYW B;  4W9J B;  4W9C B;  5DAD A;  4CXJ A;  1FS1 B;  1A68 A;  4BKT B;  1QDV A;  4W9E B;  3HU6 A;  3HQI A;  1LM8 C;  1S1G A;  2NN2 A;  3OHV A;  1EOD A;  3LUT B;  3BIM A;  3C6O A;  5FTA A;  4JTC B;  5BO4 C;  3C6N A;  2OVQ A;  4W9D B;  3ZKJ B;  2IZV C;  3ZTD B;  4W9H H;  5H7H A;  3V7D A;  4W9G B;  2IHC A;  2NZ0 B;  1LDK D;  5IBK A;  2P1M A;  3ZUN B;  4B9K B;  5BXD A;  3M8V A;  2VKP A;  3M5B A;  3OGK A;  3M4T A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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