4FGTA

Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
283
structure length
265
Chain Sequence
GELQYLGQIQHILRCGVRADDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPHALQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
publication title Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
pubmed doi rcsb
molecule keywords Thymidylate synthase
total genus 84
structure length 265
sequence length 283
ec nomenclature ec 2.1.1.45: Thymidylate synthase.
pdb deposition date 2012-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00303 Thymidylat_synt Thymidylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase; Chain A Thymidylate synthase/dCMP hydroxymethylase domain 4fgtA00
2RDAA 4Q0DA 4TMSA 3HB8A 1NJDA 4KY4A 3UM5A 1JTQA 2BBQA 3KJSA 4H1IA 4O1XD 3CL9A 3EF9A 4DPHA 4E28A 3QGTA 3N5EB 1EV8A 1I00A 3EHIX 3IROA 1BQ2A 1J3KC 1JMHA 4GYHA 1AXWA 1HVYA 5HS3A 3DGAC 3B5BA 4DPDA 4KPWA 1FWMA 1TVVA 1TYSA 5H39A 1TSZA 1TSMA 2FTOX 3N5EA 1VZAA 1QZFA 4EILA 1BKOA 1BQ1A 4GD7A 1LCBA 1LCEA 3GG5A 4FGTA 3EJLA 1TSLA 2TSRA 3N5GA 3ED7A 4F2VA 3IK0A 1TDUA 1TLSA 2TDDA 1BSPA 1NJEA 4UP1A 3INVA 1F4GA 4ISKA 3IK1A 4DQ1A 4KNZA 2A9WA 1DNAA 3C0AA 1J3IC 3IRMA 1BDUA 4IQQA 1BJGA 1HZWA 3OB7A 4IQBA 1KZIA 1TVWA 1NCEA 4IRRA 2FTNA 1TDAA 1THYA 2FTQA 3B9HA 1F4EA 1F4FA 1TRGA 3EDWX 5BY6A 3DL6A 4G6WX 2H2QA 2OIPA 4FOAA 1AN5A 1TISA 4FOXA 3BYXA 1BKPA 1BO7A 3DG8C 1TDBA 3GH0A 3QG2A 5H3AA 4O1XA 1DDUA 1BSFA 3BNZA 5FCTA 1TSYA 1LCAA 3HBBA 4EZ8A 1CI7A 3CLBA 2ONBA 4H0RA 1TDCA 1KZJA 4E5OA 1TVUA 5WRNA 1QQQA 1VZEA 3BHRA 3KJRA 2G89A 1B5DA 3BHLA 1SEJA 3KGBA 4XSEA 5J7WA 1B49A 3IJZA 1RTSA 3EAWX 1F4BA 3BGXA 5H38A 3NRRA 4FQSA 2AAZA 2G8XA 3V8HA 3UM8A 2RD8B 4Q0EA 1HW4A 1F4CA 4KYAA 4EB4A 3TMSA 1JMFA 3EBUA 2G8AA 3BZ0A 1AOBA 2RD8A 1EVFA 1F28A 1J3JC 4O7UA 1FFLA 3JSUA 4PSGA 2VETA 1F4DA 1JU6A 1BIDA 1AIQA 1TSWA 1NJBA 1EV5A 1JUTA 3IHIA 4XSDA 1BPJA 1TSVA 2G86A 1KCEA 3GH2X 3K2HA 1JMGA 3QJ7A 3C06A 3BFIA 4G2OX 1TJSA 2G8DA 1HW3A 4ISWA 1B02A 1BP6A 1JMIA 1YPVA 1ZPRA 3DL5A 3EGYX 1TSNA 3IRNA 3IX6A 1TSDA 3HJ3A 1VZBA 3UM6A 1BP0A 4KY8A 1SYNA 1AJMA 1BO8A 4FOGA 2TSCA 3UWLB 1TLCA 4ECKA 1TSXA 4JEFA 1EVGA 2VF0A 3H9KA 1VZCA 3UWLA 4EINA 4DP3A 3I3RA 4LRRA 1JG0A 1JTUA 2KCEA 4H0UA 1JUJA 1B5EA 1NJAA 4O1UA 4XSCA 2TDMA 1VZDA 4GEVA 1NJCA
chains in the Genus database with same CATH superfamily
2RDAA 4Q0DA 4TMSA 3HB8A 1NJDA 4KY4A 3UM5A 1JTQA 2BBQA 3KJSA 4H1IA 4O1XD 3CL9A 3EF9A 4DPHA 4E28A 3QGTA 3N5EB 1EV8A 1I00A 3EHIX 3IROA 1BQ2A 1J3KC 1JMHA 4GYHA 1AXWA 1HVYA 5HS3A 3DGAC 3B5BA 4DPDA 4KPWA 1FWMA 1TVVA 1TYSA 5H39A 1TSZA 1TSMA 2FTOX 3N5EA 1VZAA 1QZFA 4EILA 1BKOA 1BQ1A 4GD7A 1LCBA 1LCEA 3GG5A 4FGTA 3EJLA 1TSLA 2TSRA 3N5GA 3ED7A 4F2VA 3IK0A 1TDUA 1TLSA 2TDDA 1BSPA 1NJEA 4UP1A 3INVA 1F4GA 4ISKA 3IK1A 4DQ1A 4KNZA 2A9WA 1DNAA 3C0AA 1J3IC 3IRMA 1BDUA 4IQQA 1BJGA 1HZWA 3OB7A 4IQBA 1KZIA 1TVWA 1NCEA 4IRRA 2FTNA 1TDAA 1THYA 2FTQA 3B9HA 1F4EA 1F4FA 1TRGA 3EDWX 5BY6A 3DL6A 4G6WX 2H2QA 2OIPA 4FOAA 1AN5A 1TISA 4FOXA 3BYXA 1BKPA 1BO7A 3DG8C 1TDBA 3GH0A 3QG2A 5H3AA 4O1XA 1DDUA 1BSFA 3BNZA 5FCTA 1TSYA 1LCAA 3HBBA 4EZ8A 1CI7A 3CLBA 2ONBA 4H0RA 1TDCA 1KZJA 4E5OA 1TVUA 5WRNA 1QQQA 1VZEA 3BHRA 3KJRA 2G89A 1B5DA 3BHLA 1SEJA 3KGBA 4XSEA 5J7WA 1B49A 3IJZA 1RTSA 3EAWX 1F4BA 3BGXA 5H38A 3NRRA 4FQSA 2AAZA 2G8XA 3V8HA 3UM8A 2RD8B 4Q0EA 1HW4A 1F4CA 4KYAA 4EB4A 3TMSA 1JMFA 3EBUA 2G8AA 3BZ0A 1AOBA 2RD8A 1EVFA 1F28A 1J3JC 4O7UA 1FFLA 3JSUA 4PSGA 2VETA 1F4DA 1JU6A 1BIDA 1AIQA 1TSWA 1NJBA 1EV5A 1JUTA 3IHIA 4XSDA 1BPJA 1TSVA 2G86A 1KCEA 3GH2X 3K2HA 1JMGA 3QJ7A 3C06A 3BFIA 4G2OX 1TJSA 2G8DA 1HW3A 4ISWA 1B02A 1BP6A 1JMIA 1YPVA 1ZPRA 3DL5A 3EGYX 1TSNA 3IRNA 3IX6A 1TSDA 3HJ3A 1VZBA 3UM6A 1BP0A 4KY8A 1SYNA 1AJMA 1BO8A 4FOGA 2TSCA 3UWLB 1TLCA 4ECKA 1TSXA 4JEFA 1EVGA 2VF0A 3H9KA 1VZCA 3UWLA 4EINA 4DP3A 3I3RA 4LRRA 1JG0A 1JTUA 2KCEA 4H0UA 1JUJA 1B5EA 1NJAA 4O1UA 4XSCA 2TDMA 1VZDA 4GEVA 1NJCA
chains in the Genus database with same CATH topology
2RDAA 4Q0DA 4TMSA 3HB8A 1NJDA 4KY4A 3UM5A 1JTQA 2BBQA 3KJSA 4H1IA 4O1XD 3CL9A 3EF9A 4DPHA 4E28A 3QGTA 3N5EB 1EV8A 1I00A 3EHIX 3IROA 1BQ2A 1J3KC 1JMHA 4GYHA 1AXWA 1HVYA 5HS3A 3DGAC 3B5BA 4DPDA 4KPWA 1FWMA 1TVVA 1TYSA 5H39A 1TSZA 1TSMA 2FTOX 3N5EA 1VZAA 1QZFA 4EILA 1BKOA 1BQ1A 4GD7A 1LCBA 1LCEA 3GG5A 4FGTA 3EJLA 1TSLA 2TSRA 3N5GA 3ED7A 4F2VA 3IK0A 1TDUA 1TLSA 2TDDA 1BSPA 1NJEA 4UP1A 3INVA 1F4GA 4ISKA 3IK1A 4DQ1A 4KNZA 2A9WA 1DNAA 3C0AA 1J3IC 3IRMA 1BDUA 4IQQA 1BJGA 1HZWA 3OB7A 4IQBA 1KZIA 1TVWA 1NCEA 4IRRA 2FTNA 1TDAA 1THYA 2FTQA 3B9HA 1F4EA 1F4FA 1TRGA 3EDWX 5BY6A 3DL6A 4G6WX 2H2QA 2OIPA 4FOAA 1AN5A 1TISA 4FOXA 3BYXA 1BKPA 1BO7A 3DG8C 1TDBA 3GH0A 3QG2A 5H3AA 4O1XA 1DDUA 1BSFA 3BNZA 5FCTA 1TSYA 1LCAA 3HBBA 4EZ8A 1CI7A 3CLBA 2ONBA 4H0RA 1TDCA 1KZJA 4E5OA 1TVUA 5WRNA 1QQQA 1VZEA 3BHRA 3KJRA 2G89A 1B5DA 3BHLA 1SEJA 3KGBA 4XSEA 5J7WA 1B49A 3IJZA 1RTSA 3EAWX 1F4BA 3BGXA 5H38A 3NRRA 4FQSA 2AAZA 2G8XA 3V8HA 3UM8A 2RD8B 4Q0EA 1HW4A 1F4CA 4KYAA 4EB4A 3TMSA 1JMFA 3EBUA 2G8AA 3BZ0A 1AOBA 2RD8A 1EVFA 1F28A 1J3JC 4O7UA 1FFLA 3JSUA 4PSGA 2VETA 1F4DA 1JU6A 1BIDA 1AIQA 1TSWA 1NJBA 1EV5A 1JUTA 3IHIA 4XSDA 1BPJA 1TSVA 2G86A 1KCEA 3GH2X 3K2HA 1JMGA 3QJ7A 3C06A 3BFIA 4G2OX 1TJSA 2G8DA 1HW3A 4ISWA 1B02A 1BP6A 1JMIA 1YPVA 1ZPRA 3DL5A 3EGYX 1TSNA 3IRNA 3IX6A 1TSDA 3HJ3A 1VZBA 3UM6A 1BP0A 4KY8A 1SYNA 1AJMA 1BO8A 4FOGA 2TSCA 3UWLB 1TLCA 4ECKA 1TSXA 4JEFA 1EVGA 2VF0A 3H9KA 1VZCA 3UWLA 4EINA 4DP3A 3I3RA 4LRRA 1JG0A 1JTUA 2KCEA 4H0UA 1JUJA 1B5EA 1NJAA 4O1UA 4XSCA 2TDMA 1VZDA 4GEVA 1NJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RDA A;  4Q0D A;  4TMS A;  3HB8 A;  1NJD A;  4KY4 A;  3UM5 A;  1JTQ A;  2BBQ A;  3KJS A;  4H1I A;  4O1X D;  3CL9 A;  3EF9 A;  4DPH A;  4E28 A;  3QGT A;  3N5E B;  1EV8 A;  1I00 A;  3EHI X;  3IRO A;  1BQ2 A;  1J3K C;  1JMH A;  4GYH A;  1AXW A;  1HVY A;  5HS3 A;  3DGA C;  3B5B A;  4DPD A;  4KPW A;  1FWM A;  1TVV A;  1TYS A;  5H39 A;  1TSZ A;  1TSM A;  2FTO X;  3N5E A;  1VZA A;  1QZF A;  4EIL A;  1BKO A;  1BQ1 A;  4GD7 A;  1LCB A;  1LCE A;  3GG5 A;  4FGT A;  3EJL A;  1TSL A;  2TSR A;  3N5G A;  3ED7 A;  4F2V A;  3IK0 A;  1TDU A;  1TLS A;  2TDD A;  1BSP A;  1NJE A;  4UP1 A;  3INV A;  1F4G A;  4ISK A;  3IK1 A;  4DQ1 A;  4KNZ A;  2A9W A;  1DNA A;  3C0A A;  1J3I C;  3IRM A;  1BDU A;  4IQQ A;  1BJG A;  1HZW A;  3OB7 A;  4IQB A;  1KZI A;  1TVW A;  1NCE A;  4IRR A;  2FTN A;  1TDA A;  1THY A;  2FTQ A;  3B9H A;  1F4E A;  1F4F A;  1TRG A;  3EDW X;  5BY6 A;  3DL6 A;  4G6W X;  2H2Q A;  2OIP A;  4FOA A;  1AN5 A;  1TIS A;  4FOX A;  3BYX A;  1BKP A;  1BO7 A;  3DG8 C;  1TDB A;  3GH0 A;  3QG2 A;  5H3A A;  4O1X A;  1DDU A;  1BSF A;  3BNZ A;  5FCT A;  1TSY A;  1LCA A;  3HBB A;  4EZ8 A;  1CI7 A;  3CLB A;  2ONB A;  4H0R A;  1TDC A;  1KZJ A;  4E5O A;  1TVU A;  5WRN A;  1QQQ A;  1VZE A;  3BHR A;  3KJR A;  2G89 A;  1B5D A;  3BHL A;  1SEJ A;  3KGB A;  4XSE A;  5J7W A;  1B49 A;  3IJZ A;  1RTS A;  3EAW X;  1F4B A;  3BGX A;  5H38 A;  3NRR A;  4FQS A;  2AAZ A;  2G8X A;  3V8H A;  3UM8 A;  2RD8 B;  4Q0E A;  1HW4 A;  1F4C A;  4KYA A;  4EB4 A;  3TMS A;  1JMF A;  3EBU A;  2G8A A;  3BZ0 A;  1AOB A;  2RD8 A;  1EVF A;  1F28 A;  1J3J C;  4O7U A;  1FFL A;  3JSU A;  4PSG A;  2VET A;  1F4D A;  1JU6 A;  1BID A;  1AIQ A;  1TSW A;  1NJB A;  1EV5 A;  1JUT A;  3IHI A;  4XSD A;  1BPJ A;  1TSV A;  2G86 A;  1KCE A;  3GH2 X;  3K2H A;  1JMG A;  3QJ7 A;  3C06 A;  3BFI A;  4G2O X;  1TJS A;  2G8D A;  1HW3 A;  4ISW A;  1B02 A;  1BP6 A;  1JMI A;  1YPV A;  1ZPR A;  3DL5 A;  3EGY X;  1TSN A;  3IRN A;  3IX6 A;  1TSD A;  3HJ3 A;  1VZB A;  3UM6 A;  1BP0 A;  4KY8 A;  1SYN A;  1AJM A;  1BO8 A;  4FOG A;  2TSC A;  3UWL B;  1TLC A;  4ECK A;  1TSX A;  4JEF A;  1EVG A;  2VF0 A;  3H9K A;  1VZC A;  3UWL A;  4EIN A;  4DP3 A;  3I3R A;  4LRR A;  1JG0 A;  1JTU A;  2KCE A;  4H0U A;  1JUJ A;  1B5E A;  1NJA A;  4O1U A;  4XSC A;  2TDM A;  1VZD A;  4GEV A;  1NJC A; 
#chains in the Genus database with same CATH topology
 2RDA A;  4Q0D A;  4TMS A;  3HB8 A;  1NJD A;  4KY4 A;  3UM5 A;  1JTQ A;  2BBQ A;  3KJS A;  4H1I A;  4O1X D;  3CL9 A;  3EF9 A;  4DPH A;  4E28 A;  3QGT A;  3N5E B;  1EV8 A;  1I00 A;  3EHI X;  3IRO A;  1BQ2 A;  1J3K C;  1JMH A;  4GYH A;  1AXW A;  1HVY A;  5HS3 A;  3DGA C;  3B5B A;  4DPD A;  4KPW A;  1FWM A;  1TVV A;  1TYS A;  5H39 A;  1TSZ A;  1TSM A;  2FTO X;  3N5E A;  1VZA A;  1QZF A;  4EIL A;  1BKO A;  1BQ1 A;  4GD7 A;  1LCB A;  1LCE A;  3GG5 A;  4FGT A;  3EJL A;  1TSL A;  2TSR A;  3N5G A;  3ED7 A;  4F2V A;  3IK0 A;  1TDU A;  1TLS A;  2TDD A;  1BSP A;  1NJE A;  4UP1 A;  3INV A;  1F4G A;  4ISK A;  3IK1 A;  4DQ1 A;  4KNZ A;  2A9W A;  1DNA A;  3C0A A;  1J3I C;  3IRM A;  1BDU A;  4IQQ A;  1BJG A;  1HZW A;  3OB7 A;  4IQB A;  1KZI A;  1TVW A;  1NCE A;  4IRR A;  2FTN A;  1TDA A;  1THY A;  2FTQ A;  3B9H A;  1F4E A;  1F4F A;  1TRG A;  3EDW X;  5BY6 A;  3DL6 A;  4G6W X;  2H2Q A;  2OIP A;  4FOA A;  1AN5 A;  1TIS A;  4FOX A;  3BYX A;  1BKP A;  1BO7 A;  3DG8 C;  1TDB A;  3GH0 A;  3QG2 A;  5H3A A;  4O1X A;  1DDU A;  1BSF A;  3BNZ A;  5FCT A;  1TSY A;  1LCA A;  3HBB A;  4EZ8 A;  1CI7 A;  3CLB A;  2ONB A;  4H0R A;  1TDC A;  1KZJ A;  4E5O A;  1TVU A;  5WRN A;  1QQQ A;  1VZE A;  3BHR A;  3KJR A;  2G89 A;  1B5D A;  3BHL A;  1SEJ A;  3KGB A;  4XSE A;  5J7W A;  1B49 A;  3IJZ A;  1RTS A;  3EAW X;  1F4B A;  3BGX A;  5H38 A;  3NRR A;  4FQS A;  2AAZ A;  2G8X A;  3V8H A;  3UM8 A;  2RD8 B;  4Q0E A;  1HW4 A;  1F4C A;  4KYA A;  4EB4 A;  3TMS A;  1JMF A;  3EBU A;  2G8A A;  3BZ0 A;  1AOB A;  2RD8 A;  1EVF A;  1F28 A;  1J3J C;  4O7U A;  1FFL A;  3JSU A;  4PSG A;  2VET A;  1F4D A;  1JU6 A;  1BID A;  1AIQ A;  1TSW A;  1NJB A;  1EV5 A;  1JUT A;  3IHI A;  4XSD A;  1BPJ A;  1TSV A;  2G86 A;  1KCE A;  3GH2 X;  3K2H A;  1JMG A;  3QJ7 A;  3C06 A;  3BFI A;  4G2O X;  1TJS A;  2G8D A;  1HW3 A;  4ISW A;  1B02 A;  1BP6 A;  1JMI A;  1YPV A;  1ZPR A;  3DL5 A;  3EGY X;  1TSN A;  3IRN A;  3IX6 A;  1TSD A;  3HJ3 A;  1VZB A;  3UM6 A;  1BP0 A;  4KY8 A;  1SYN A;  1AJM A;  1BO8 A;  4FOG A;  2TSC A;  3UWL B;  1TLC A;  4ECK A;  1TSX A;  4JEF A;  1EVG A;  2VF0 A;  3H9K A;  1VZC A;  3UWL A;  4EIN A;  4DP3 A;  3I3R A;  4LRR A;  1JG0 A;  1JTU A;  2KCE A;  4H0U A;  1JUJ A;  1B5E A;  1NJA A;  4O1U A;  4XSC A;  2TDM A;  1VZD A;  4GEV A;  1NJC A; 
#chains in the Genus database with same CATH homology
 2RDA A;  4Q0D A;  4TMS A;  3HB8 A;  1NJD A;  4KY4 A;  3UM5 A;  1JTQ A;  2BBQ A;  3KJS A;  4H1I A;  4O1X D;  3CL9 A;  3EF9 A;  4DPH A;  4E28 A;  3QGT A;  3N5E B;  1EV8 A;  1I00 A;  3EHI X;  3IRO A;  1BQ2 A;  1J3K C;  1JMH A;  4GYH A;  1AXW A;  1HVY A;  5HS3 A;  3DGA C;  3B5B A;  4DPD A;  4KPW A;  1FWM A;  1TVV A;  1TYS A;  5H39 A;  1TSZ A;  1TSM A;  2FTO X;  3N5E A;  1VZA A;  1QZF A;  4EIL A;  1BKO A;  1BQ1 A;  4GD7 A;  1LCB A;  1LCE A;  3GG5 A;  4FGT A;  3EJL A;  1TSL A;  2TSR A;  3N5G A;  3ED7 A;  4F2V A;  3IK0 A;  1TDU A;  1TLS A;  2TDD A;  1BSP A;  1NJE A;  4UP1 A;  3INV A;  1F4G A;  4ISK A;  3IK1 A;  4DQ1 A;  4KNZ A;  2A9W A;  1DNA A;  3C0A A;  1J3I C;  3IRM A;  1BDU A;  4IQQ A;  1BJG A;  1HZW A;  3OB7 A;  4IQB A;  1KZI A;  1TVW A;  1NCE A;  4IRR A;  2FTN A;  1TDA A;  1THY A;  2FTQ A;  3B9H A;  1F4E A;  1F4F A;  1TRG A;  3EDW X;  5BY6 A;  3DL6 A;  4G6W X;  2H2Q A;  2OIP A;  4FOA A;  1AN5 A;  1TIS A;  4FOX A;  3BYX A;  1BKP A;  1BO7 A;  3DG8 C;  1TDB A;  3GH0 A;  3QG2 A;  5H3A A;  4O1X A;  1DDU A;  1BSF A;  3BNZ A;  5FCT A;  1TSY A;  1LCA A;  3HBB A;  4EZ8 A;  1CI7 A;  3CLB A;  2ONB A;  4H0R A;  1TDC A;  1KZJ A;  4E5O A;  1TVU A;  5WRN A;  1QQQ A;  1VZE A;  3BHR A;  3KJR A;  2G89 A;  1B5D A;  3BHL A;  1SEJ A;  3KGB A;  4XSE A;  5J7W A;  1B49 A;  3IJZ A;  1RTS A;  3EAW X;  1F4B A;  3BGX A;  5H38 A;  3NRR A;  4FQS A;  2AAZ A;  2G8X A;  3V8H A;  3UM8 A;  2RD8 B;  4Q0E A;  1HW4 A;  1F4C A;  4KYA A;  4EB4 A;  3TMS A;  1JMF A;  3EBU A;  2G8A A;  3BZ0 A;  1AOB A;  2RD8 A;  1EVF A;  1F28 A;  1J3J C;  4O7U A;  1FFL A;  3JSU A;  4PSG A;  2VET A;  1F4D A;  1JU6 A;  1BID A;  1AIQ A;  1TSW A;  1NJB A;  1EV5 A;  1JUT A;  3IHI A;  4XSD A;  1BPJ A;  1TSV A;  2G86 A;  1KCE A;  3GH2 X;  3K2H A;  1JMG A;  3QJ7 A;  3C06 A;  3BFI A;  4G2O X;  1TJS A;  2G8D A;  1HW3 A;  4ISW A;  1B02 A;  1BP6 A;  1JMI A;  1YPV A;  1ZPR A;  3DL5 A;  3EGY X;  1TSN A;  3IRN A;  3IX6 A;  1TSD A;  3HJ3 A;  1VZB A;  3UM6 A;  1BP0 A;  4KY8 A;  1SYN A;  1AJM A;  1BO8 A;  4FOG A;  2TSC A;  3UWL B;  1TLC A;  4ECK A;  1TSX A;  4JEF A;  1EVG A;  2VF0 A;  3H9K A;  1VZC A;  3UWL A;  4EIN A;  4DP3 A;  3I3R A;  4LRR A;  1JG0 A;  1JTU A;  2KCE A;  4H0U A;  1JUJ A;  1B5E A;  1NJA A;  4O1U A;  4XSC A;  2TDM A;  1VZD A;  4GEV A;  1NJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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