4JGHC

Structure of the socs2-elongin bc complex bound to an n-terminal fragment of cullin5
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
96
structure length
96
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIPLELLMAANFLDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Suppressor of cytokine signaling 2
total genus 25
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2013-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 4jghC00
3ZKJB 2YY9A 4AWJB 3V7DA 4U77A 1FS2B 4UIJA 1R28A 1VCBB 5H7HA 4U2NA 2P1OA 2VKPA 4W9DB 3KVTA 3M4TA 3WSOB 1A68A 4WQOC 3DCGB 3GA1A 4W9EB 4HXIA 4CXIA 3ZTCB 3E4UA 4APFA 3MKSA 4BKSB 1R2BA 4W9HH 4ZOUA 2IZVC 1LQBB 3HTMA 1FQVB 2MA9C 1T1DA 3HU6A 5BXHA 4W9CB 5BXBA 1LM8C 2P1MA 3OGLA 4JTDB 4W9LB 3LUTB 3HQIA 2OVPA 3C6OA 2R9RB 4W9GB 3ZRCB 5H7GA 1HV2A 4W9HB 3HVEA 5DADA 5FTAA 2P1QA 2Q81A 4U2MA 3B84A 4CXTA 4JGHC 2NN2A 1NN7A 4UYIA 4JTCB 3I3NA 2E32B 3ZTDB 4CRHA 5BO4C 3ZNGB 2JZ3C 1EXBE 1EOFA 4B95B 2IF5A 3ZUNB 4EOZA 1EODA 5IBKA 5A6RA 3FKCA 1DSXA 4I6JC 1CS3A 2E31B 4CXJA 4CP3A 3OGKA 3LBZA 4B9KB 3C6PA 1P22B 4AJYC 3OHUA 1EOEA 5LLIB 2PPIA 4JTAB 3OHVA 5BXDA 2FNJC 1NEXA 2P1PA 1QDWA 1BUOA 5JH5B 2Z8HA 3BIMA 1FS1B 1LDKD 3LNMB 5EUPA 4B9KE 4W9IB 3M52A 4W9FB 2ASTA 4J8ZA 2NZ0B 2OVQA 2A79B 5HZGC 2P1NA 3HVEB 5DAFA 3DRZA 2ASSA 1S1GA 4W9JB 4N9F5 3M5BA 1QDVA 3ZRFB 4BKTB 3L2OA 4W9KB 2VPKA 2IHCA 3OGMA 2OVRA 3M8VA 5A15A 2C9WC 1R29A 4AP2A 5HYWB 2I2RA 3C6NA 4BGCA
chains in the Genus database with same CATH superfamily
3ZKJB 2YY9A 4AWJB 3V7DA 4U77A 1FS2B 4UIJA 1R28A 1VCBB 5H7HA 4U2NA 2P1OA 2VKPA 4W9DB 3KVTA 3M4TA 3WSOB 1A68A 4WQOC 3DCGB 3GA1A 4W9EB 4HXIA 4CXIA 3ZTCB 3E4UA 4APFA 3MKSA 4BKSB 1R2BA 4W9HH 4ZOUA 2IZVC 3HTMA 1LQBB 1FQVB 2MA9C 1T1DA 3HU6A 5BXHA 4W9CB 5BXBA 1LM8C 2P1MA 3OGLA 4JTDB 4W9LB 3LUTB 3HQIA 2OVPA 3C6OA 2R9RB 4W9GB 3ZRCB 5H7GA 1HV2A 4W9HB 3HVEA 5DADA 5FTAA 2P1QA 2Q81A 4U2MA 3B84A 4CXTA 4JGHC 2NN2A 1NN7A 4UYIA 4JTCB 3I3NA 2E32B 3ZTDB 4CRHA 4YY8A 5BO4C 3ZNGB 4ZGCA 2JZ3C 1EXBE 1EOFA 4B95B 2IF5A 3ZUNB 4EOZA 1EODA 5IBKA 5A6RA 3FKCA 1DSXA 4I6JC 1CS3A 2E31B 4CXJA 4CP3A 3OGKA 3LBZA 4B9KB 3C6PA 1P22B 4AJYC 3OHUA 1EOEA 5LLIB 2PPIA 4JTAB 3OHVA 5BXDA 2FNJC 1NEXA 2P1PA 1QDWA 1BUOA 5JH5B 2Z8HA 3DRXA 3BIMA 1FS1B 1LDKD 3LNMB 5EUPA 4B9KE 4W9IB 3M52A 4W9FB 2ASTA 4J8ZA 2NZ0B 2OVQA 2A79B 5HZGC 2P1NA 3HVEB 5DAFA 3DRZA 2ASSA 1S1GA 4W9JB 4N9F5 3M5BA 1QDVA 3ZRFB 4BKTB 3L2OA 4W9KB 2VPKA 2IHCA 3OGMA 2OVRA 3M8VA 5A15A 2C9WC 1R29A 4AP2A 5HYWB 3DRYA 2I2RA 3C6NA 4BGCA
chains in the Genus database with same CATH topology
3ZKJB 2YY9A 4AWJB 3V7DA 4U77A 1FS2B 4UIJA 1R28A 1VCBB 5H7HA 4U2NA 2P1OA 2VKPA 4W9DB 3KVTA 3M4TA 3WSOB 1A68A 4WQOC 3DCGB 3GA1A 4W9EB 4HXIA 4CXIA 3ZTCB 3E4UA 4APFA 3MKSA 4BKSB 1R2BA 4W9HH 4ZOUA 2IZVC 3HTMA 1LQBB 1FQVB 2MA9C 1T1DA 3HU6A 5BXHA 4W9CB 5BXBA 1LM8C 2P1MA 3OGLA 4JTDB 4W9LB 3LUTB 3HQIA 2OVPA 3C6OA 2R9RB 4W9GB 3ZRCB 5H7GA 1HV2A 4W9HB 3HVEA 5DADA 5FTAA 2P1QA 2Q81A 4U2MA 3B84A 4CXTA 4JGHC 2NN2A 1NN7A 4UYIA 4JTCB 3I3NA 2E32B 3ZTDB 4CRHA 4YY8A 5BO4C 3ZNGB 4ZGCA 2JZ3C 1EXBE 1EOFA 4B95B 2IF5A 3ZUNB 4EOZA 1EODA 5IBKA 5A6RA 3FKCA 1DSXA 4I6JC 1CS3A 2E31B 4CXJA 4CP3A 3OGKA 3LBZA 4B9KB 3C6PA 1P22B 4AJYC 3OHUA 1EOEA 5LLIB 2PPIA 4JTAB 3OHVA 5BXDA 2FNJC 1NEXA 2P1PA 1QDWA 1BUOA 5JH5B 2Z8HA 3DRXA 3BIMA 1FS1B 1LDKD 3LNMB 5EUPA 4B9KE 4W9IB 3M52A 4W9FB 2ASTA 4J8ZA 2NZ0B 2OVQA 2A79B 5HZGC 2P1NA 3HVEB 5DAFA 3DRZA 2ASSA 1S1GA 4W9JB 4N9F5 3M5BA 1QDVA 3ZRFB 4BKTB 3L2OA 4W9KB 2VPKA 2IHCA 3OGMA 2OVRA 3M8VA 5A15A 2C9WC 1R29A 4AP2A 5HYWB 3DRYA 2I2RA 3C6NA 4BGCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZKJ B;  2YY9 A;  4AWJ B;  3V7D A;  4U77 A;  1FS2 B;  4UIJ A;  1R28 A;  1VCB B;  5H7H A;  4U2N A;  2P1O A;  2VKP A;  4W9D B;  3KVT A;  3M4T A;  3WSO B;  1A68 A;  4WQO C;  3DCG B;  3GA1 A;  4W9E B;  4HXI A;  4CXI A;  3ZTC B;  3E4U A;  4APF A;  3MKS A;  4BKS B;  1R2B A;  4W9H H;  4ZOU A;  2IZV C;  1LQB B;  3HTM A;  1FQV B;  2MA9 C;  1T1D A;  3HU6 A;  5BXH A;  4W9C B;  5BXB A;  1LM8 C;  2P1M A;  3OGL A;  4JTD B;  4W9L B;  3LUT B;  3HQI A;  2OVP A;  3C6O A;  2R9R B;  4W9G B;  3ZRC B;  5H7G A;  1HV2 A;  4W9H B;  3HVE A;  5DAD A;  5FTA A;  2P1Q A;  2Q81 A;  4U2M A;  3B84 A;  4CXT A;  4JGH C;  2NN2 A;  1NN7 A;  4UYI A;  4JTC B;  3I3N A;  2E32 B;  3ZTD B;  4CRH A;  5BO4 C;  3ZNG B;  2JZ3 C;  1EXB E;  1EOF A;  4B95 B;  2IF5 A;  3ZUN B;  4EOZ A;  1EOD A;  5IBK A;  5A6R A;  3FKC A;  1DSX A;  4I6J C;  1CS3 A;  2E31 B;  4CXJ A;  4CP3 A;  3OGK A;  3LBZ A;  4B9K B;  3C6P A;  1P22 B;  4AJY C;  3OHU A;  1EOE A;  5LLI B;  2PPI A;  4JTA B;  3OHV A;  5BXD A;  2FNJ C;  1NEX A;  2P1P A;  1QDW A;  1BUO A;  5JH5 B;  2Z8H A;  3BIM A;  1FS1 B;  1LDK D;  3LNM B;  5EUP A;  4B9K E;  4W9I B;  3M52 A;  4W9F B;  2AST A;  4J8Z A;  2NZ0 B;  2OVQ A;  2A79 B;  5HZG C;  2P1N A;  3HVE B;  5DAF A;  3DRZ A;  2ASS A;  1S1G A;  4W9J B;  4N9F 5;  3M5B A;  1QDV A;  3ZRF B;  4BKT B;  3L2O A;  4W9K B;  2VPK A;  2IHC A;  3OGM A;  2OVR A;  3M8V A;  5A15 A;  2C9W C;  1R29 A;  4AP2 A;  5HYW B;  2I2R A;  3C6N A;  4BGC A; 
#chains in the Genus database with same CATH topology
 3ZKJ B;  2YY9 A;  4AWJ B;  3V7D A;  4U77 A;  1FS2 B;  4UIJ A;  1R28 A;  1VCB B;  5H7H A;  4U2N A;  2P1O A;  2VKP A;  4W9D B;  3KVT A;  3M4T A;  3WSO B;  1A68 A;  4WQO C;  3DCG B;  3GA1 A;  4W9E B;  4HXI A;  4CXI A;  3ZTC B;  3E4U A;  4APF A;  3MKS A;  4BKS B;  1R2B A;  4W9H H;  4ZOU A;  2IZV C;  3HTM A;  1LQB B;  1FQV B;  2MA9 C;  1T1D A;  3HU6 A;  5BXH A;  4W9C B;  5BXB A;  1LM8 C;  2P1M A;  3OGL A;  4JTD B;  4W9L B;  3LUT B;  3HQI A;  2OVP A;  3C6O A;  2R9R B;  4W9G B;  3ZRC B;  5H7G A;  1HV2 A;  4W9H B;  3HVE A;  5DAD A;  5FTA A;  2P1Q A;  2Q81 A;  4U2M A;  3B84 A;  4CXT A;  4JGH C;  2NN2 A;  1NN7 A;  4UYI A;  4JTC B;  3I3N A;  2E32 B;  3ZTD B;  4CRH A;  4YY8 A;  5BO4 C;  3ZNG B;  4ZGC A;  2JZ3 C;  1EXB E;  1EOF A;  4B95 B;  2IF5 A;  3ZUN B;  4EOZ A;  1EOD A;  5IBK A;  5A6R A;  3FKC A;  1DSX A;  4I6J C;  1CS3 A;  2E31 B;  4CXJ A;  4CP3 A;  3OGK A;  3LBZ A;  4B9K B;  3C6P A;  1P22 B;  4AJY C;  3OHU A;  1EOE A;  5LLI B;  2PPI A;  4JTA B;  3OHV A;  5BXD A;  2FNJ C;  1NEX A;  2P1P A;  1QDW A;  1BUO A;  5JH5 B;  2Z8H A;  3DRX A;  3BIM A;  1FS1 B;  1LDK D;  3LNM B;  5EUP A;  4B9K E;  4W9I B;  3M52 A;  4W9F B;  2AST A;  4J8Z A;  2NZ0 B;  2OVQ A;  2A79 B;  5HZG C;  2P1N A;  3HVE B;  5DAF A;  3DRZ A;  2ASS A;  1S1G A;  4W9J B;  4N9F 5;  3M5B A;  1QDV A;  3ZRF B;  4BKT B;  3L2O A;  4W9K B;  2VPK A;  2IHC A;  3OGM A;  2OVR A;  3M8V A;  5A15 A;  2C9W C;  1R29 A;  4AP2 A;  5HYW B;  3DRY A;  2I2R A;  3C6N A;  4BGC A; 
#chains in the Genus database with same CATH homology
 3ZKJ B;  2YY9 A;  4AWJ B;  3V7D A;  4U77 A;  1FS2 B;  4UIJ A;  1R28 A;  1VCB B;  5H7H A;  4U2N A;  2P1O A;  2VKP A;  4W9D B;  3KVT A;  3M4T A;  3WSO B;  1A68 A;  4WQO C;  3DCG B;  3GA1 A;  4W9E B;  4HXI A;  4CXI A;  3ZTC B;  3E4U A;  4APF A;  3MKS A;  4BKS B;  1R2B A;  4W9H H;  4ZOU A;  2IZV C;  3HTM A;  1LQB B;  1FQV B;  2MA9 C;  1T1D A;  3HU6 A;  5BXH A;  4W9C B;  5BXB A;  1LM8 C;  2P1M A;  3OGL A;  4JTD B;  4W9L B;  3LUT B;  3HQI A;  2OVP A;  3C6O A;  2R9R B;  4W9G B;  3ZRC B;  5H7G A;  1HV2 A;  4W9H B;  3HVE A;  5DAD A;  5FTA A;  2P1Q A;  2Q81 A;  4U2M A;  3B84 A;  4CXT A;  4JGH C;  2NN2 A;  1NN7 A;  4UYI A;  4JTC B;  3I3N A;  2E32 B;  3ZTD B;  4CRH A;  4YY8 A;  5BO4 C;  3ZNG B;  4ZGC A;  2JZ3 C;  1EXB E;  1EOF A;  4B95 B;  2IF5 A;  3ZUN B;  4EOZ A;  1EOD A;  5IBK A;  5A6R A;  3FKC A;  1DSX A;  4I6J C;  1CS3 A;  2E31 B;  4CXJ A;  4CP3 A;  3OGK A;  3LBZ A;  4B9K B;  3C6P A;  1P22 B;  4AJY C;  3OHU A;  1EOE A;  5LLI B;  2PPI A;  4JTA B;  3OHV A;  5BXD A;  2FNJ C;  1NEX A;  2P1P A;  1QDW A;  1BUO A;  5JH5 B;  2Z8H A;  3DRX A;  3BIM A;  1FS1 B;  1LDK D;  3LNM B;  5EUP A;  4B9K E;  4W9I B;  3M52 A;  4W9F B;  2AST A;  4J8Z A;  2NZ0 B;  2OVQ A;  2A79 B;  5HZG C;  2P1N A;  3HVE B;  5DAF A;  3DRZ A;  2ASS A;  1S1G A;  4W9J B;  4N9F 5;  3M5B A;  1QDV A;  3ZRF B;  4BKT B;  3L2O A;  4W9K B;  2VPK A;  2IHC A;  3OGM A;  2OVR A;  3M8V A;  5A15 A;  2C9W C;  1R29 A;  4AP2 A;  5HYW B;  3DRY A;  2I2R A;  3C6N A;  4BGC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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