4P2IA

Crystal structure of the mouse snx19 px domain
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
133
structure length
117
Chain Sequence
PVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords MKIAA0254 protein
total genus 32
structure length 117
sequence length 133
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4p2iA00
1O7KA 2DYBA 1XTNA 2L73A 2WWEA 2V6VA 4HASA 4BGJA 4ON3A 1GD5A 4PZGA 2AR5A 2CSKA 3LUIA 2ETTA 2REDA 2CZOA 4P2IA 3DYTA 3IQ2A 4IKBB 3FOGA 4OXWA 1XTEA 1KQ6A 4P2JA 2IWLX 4PQOA 4AKVA 1OCUA 1KMDA 3HPCX 4IKBA 4IKDA 3P0CA 3HPBA 2REAA 1H6HA 2V14A 2RAIA 2RAKA 2RAJA 4AZ9A 2YPSA 1OCSA 4PQPA 2I4KA
chains in the Genus database with same CATH superfamily
1O7KA 2DYBA 1XTNA 2L73A 2WWEA 2V6VA 4HASA 4BGJA 4ON3A 1GD5A 4PZGA 2AR5A 2CSKA 3LUIA 2ETTA 2REDA 2CZOA 4P2IA 3DYTA 3IQ2A 4IKBB 3FOGA 4OXWA 1XTEA 1KQ6A 4P2JA 2IWLX 4PQOA 4AKVA 1OCUA 1KMDA 3HPCX 4IKBA 4IKDA 3P0CA 3HPBA 2REAA 1H6HA 2V14A 2RAIA 2RAKA 2RAJA 4AZ9A 2YPSA 1OCSA 4PQPA 2I4KA
chains in the Genus database with same CATH topology
1O7KA 2DYBA 1XTNA 2L73A 2WWEA 2V6VA 4HASA 4BGJA 4ON3A 1GD5A 4PZGA 2AR5A 2CSKA 3LUIA 2ETTA 2REDA 2CZOA 4P2IA 3DYTA 3IQ2A 4IKBB 3FOGA 4OXWA 1XTEA 1KQ6A 4P2JA 2IWLX 4PQOA 4AKVA 1OCUA 1KMDA 3HPCX 4IKBA 4IKDA 3P0CA 3HPBA 2REAA 1H6HA 2V14A 2RAIA 2RAKA 2RAJA 4AZ9A 2YPSA 1OCSA 4PQPA 2I4KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O7K A;  2DYB A;  1XTN A;  2L73 A;  2WWE A;  2V6V A;  4HAS A;  4BGJ A;  4ON3 A;  1GD5 A;  4PZG A;  2AR5 A;  2CSK A;  3LUI A;  2ETT A;  2RED A;  2CZO A;  4P2I A;  3DYT A;  3IQ2 A;  4IKB B;  3FOG A;  4OXW A;  1XTE A;  1KQ6 A;  4P2J A;  2IWL X;  4PQO A;  4AKV A;  1OCU A;  1KMD A;  3HPC X;  4IKB A;  4IKD A;  3P0C A;  3HPB A;  2REA A;  1H6H A;  2V14 A;  2RAI A;  2RAK A;  2RAJ A;  4AZ9 A;  2YPS A;  1OCS A;  4PQP A;  2I4K A; 
#chains in the Genus database with same CATH topology
 1O7K A;  2DYB A;  1XTN A;  2L73 A;  2WWE A;  2V6V A;  4HAS A;  4BGJ A;  4ON3 A;  1GD5 A;  4PZG A;  2AR5 A;  2CSK A;  3LUI A;  2ETT A;  2RED A;  2CZO A;  4P2I A;  3DYT A;  3IQ2 A;  4IKB B;  3FOG A;  4OXW A;  1XTE A;  1KQ6 A;  4P2J A;  2IWL X;  4PQO A;  4AKV A;  1OCU A;  1KMD A;  3HPC X;  4IKB A;  4IKD A;  3P0C A;  3HPB A;  2REA A;  1H6H A;  2V14 A;  2RAI A;  2RAK A;  2RAJ A;  4AZ9 A;  2YPS A;  1OCS A;  4PQP A;  2I4K A; 
#chains in the Genus database with same CATH homology
 1O7K A;  2DYB A;  1XTN A;  2L73 A;  2WWE A;  2V6V A;  4HAS A;  4BGJ A;  4ON3 A;  1GD5 A;  4PZG A;  2AR5 A;  2CSK A;  3LUI A;  2ETT A;  2RED A;  2CZO A;  4P2I A;  3DYT A;  3IQ2 A;  4IKB B;  3FOG A;  4OXW A;  1XTE A;  1KQ6 A;  4P2J A;  2IWL X;  4PQO A;  4AKV A;  1OCU A;  1KMD A;  3HPC X;  4IKB A;  4IKD A;  3P0C A;  3HPB A;  2REA A;  1H6H A;  2V14 A;  2RAI A;  2RAK A;  2RAJ A;  4AZ9 A;  2YPS A;  1OCS A;  4PQP A;  2I4K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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