4P2I | Genus

Total Genus 32

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	32
sequence length	133
structure length	117
Chain Sequence	PVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 117 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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117 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Mus musculus
publication title	Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. pubmed doi rcsb
molecule keywords	MKIAA0254 protein
total genus	32
structure length	117
sequence length	133
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-03-04

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00787	PX	PX domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1520.10	Alpha Beta	2-Layer Sandwich	PX Domain	Phox-like domain	4p2iA00

2ETTA 2WWEA 3LUIA 4P2JA 1KMDA 3FOGA 2REDA 2CSKA 2L73A 3HPBA 4IKBA 4AKVA 1H6HA 4BGJA 4OXWA 1GD5A 2IWLX 1OCSA 3HPCX 4P2IA 4IKDA 4AZ9A 2YPSA 2RAKA 3P0CA 4IKBB 2RAIA 1OCUA 1XTNA 1O7KA 3DYTA 4PQOA 2RAJA 4PZGA 4ON3A 2I4KA 2CZOA 2DYBA 2V6VA 3IQ2A 4PQPA 2REAA 4HASA 1KQ6A 2V14A 2AR5A 1XTEA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2ETT A;  2WWE A;  3LUI A;  4P2J A;  1KMD A;  3FOG A;  2RED A;  2CSK A;  2L73 A;  3HPB A;  4IKB A;  4AKV A;  1H6H A;  4BGJ A;  4OXW A;  1GD5 A;  2IWL X;  1OCS A;  3HPC X;  4P2I A;  4IKD A;  4AZ9 A;  2YPS A;  2RAK A;  3P0C A;  4IKB B;  2RAI A;  1OCU A;  1XTN A;  1O7K A;  3DYT A;  4PQO A;  2RAJ A;  4PZG A;  4ON3 A;  2I4K A;  2CZO A;  2DYB A;  2V6V A;  3IQ2 A;  4PQP A;  2REA A;  4HAS A;  1KQ6 A;  2V14 A;  2AR5 A;  1XTE A; 
#chains in the Genus database with same CATH topology
 2ETT A;  2WWE A;  3LUI A;  4P2J A;  1KMD A;  3FOG A;  2RED A;  2CSK A;  2L73 A;  3HPB A;  4IKB A;  4AKV A;  1H6H A;  4BGJ A;  4OXW A;  1GD5 A;  2IWL X;  1OCS A;  3HPC X;  4P2I A;  4IKD A;  4AZ9 A;  2YPS A;  2RAK A;  3P0C A;  4IKB B;  2RAI A;  1OCU A;  1XTN A;  1O7K A;  3DYT A;  4PQO A;  2RAJ A;  4PZG A;  4ON3 A;  2I4K A;  2CZO A;  2DYB A;  2V6V A;  3IQ2 A;  4PQP A;  2REA A;  4HAS A;  1KQ6 A;  2V14 A;  2AR5 A;  1XTE A; 
#chains in the Genus database with same CATH homology
 2ETT A;  2WWE A;  3LUI A;  4P2J A;  1KMD A;  3FOG A;  2RED A;  2CSK A;  2L73 A;  3HPB A;  4IKB A;  4AKV A;  1H6H A;  4BGJ A;  4OXW A;  1GD5 A;  2IWL X;  1OCS A;  3HPC X;  4P2I A;  4IKD A;  4AZ9 A;  2YPS A;  2RAK A;  3P0C A;  4IKB B;  2RAI A;  1OCU A;  1XTN A;  1O7K A;  3DYT A;  4PQO A;  2RAJ A;  4PZG A;  4ON3 A;  2I4K A;  2CZO A;  2DYB A;  2V6V A;  3IQ2 A;  4PQP A;  2REA A;  4HAS A;  1KQ6 A;  2V14 A;  2AR5 A;  1XTE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4P2IA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations