4P2J | Genus

Total Genus 31

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	31
sequence length	133
structure length	117
Chain Sequence	PVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 117 atoms

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117 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Mus musculus
publication title	Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. pubmed doi rcsb
molecule keywords	MKIAA0254 protein
total genus	31
structure length	117
sequence length	133
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-03-04

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00787	PX	PX domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1520.10	Alpha Beta	2-Layer Sandwich	PX Domain	Phox-like domain	4p2jA00

1GD5A 4IKBA 2L73A 4PQPA 2RAIA 2REAA 2RAJA 3P0CA 3LUIA 4PQOA 3HPCX 4OXWA 1OCUA 2YPSA 1XTEA 4P2JA 2CZOA 3IQ2A 2WWEA 1OCSA 2RAKA 4BGJA 4ON3A 2REDA 3FOGA 4P2IA 1KMDA 4AZ9A 2IWLX 2V6VA 1XTNA 1O7KA 4PZGA 2I4KA 3HPBA 2ETTA 4HASA 2AR5A 2CSKA 2V14A 1KQ6A 2DYBA 4AKVA 4IKBB 3DYTA 4IKDA 1H6HA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1GD5 A;  4IKB A;  2L73 A;  4PQP A;  2RAI A;  2REA A;  2RAJ A;  3P0C A;  3LUI A;  4PQO A;  3HPC X;  4OXW A;  1OCU A;  2YPS A;  1XTE A;  4P2J A;  2CZO A;  3IQ2 A;  2WWE A;  1OCS A;  2RAK A;  4BGJ A;  4ON3 A;  2RED A;  3FOG A;  4P2I A;  1KMD A;  4AZ9 A;  2IWL X;  2V6V A;  1XTN A;  1O7K A;  4PZG A;  2I4K A;  3HPB A;  2ETT A;  4HAS A;  2AR5 A;  2CSK A;  2V14 A;  1KQ6 A;  2DYB A;  4AKV A;  4IKB B;  3DYT A;  4IKD A;  1H6H A; 
#chains in the Genus database with same CATH topology
 1GD5 A;  4IKB A;  2L73 A;  4PQP A;  2RAI A;  2REA A;  2RAJ A;  3P0C A;  3LUI A;  4PQO A;  3HPC X;  4OXW A;  1OCU A;  2YPS A;  1XTE A;  4P2J A;  2CZO A;  3IQ2 A;  2WWE A;  1OCS A;  2RAK A;  4BGJ A;  4ON3 A;  2RED A;  3FOG A;  4P2I A;  1KMD A;  4AZ9 A;  2IWL X;  2V6V A;  1XTN A;  1O7K A;  4PZG A;  2I4K A;  3HPB A;  2ETT A;  4HAS A;  2AR5 A;  2CSK A;  2V14 A;  1KQ6 A;  2DYB A;  4AKV A;  4IKB B;  3DYT A;  4IKD A;  1H6H A; 
#chains in the Genus database with same CATH homology
 1GD5 A;  4IKB A;  2L73 A;  4PQP A;  2RAI A;  2REA A;  2RAJ A;  3P0C A;  3LUI A;  4PQO A;  3HPC X;  4OXW A;  1OCU A;  2YPS A;  1XTE A;  4P2J A;  2CZO A;  3IQ2 A;  2WWE A;  1OCS A;  2RAK A;  4BGJ A;  4ON3 A;  2RED A;  3FOG A;  4P2I A;  1KMD A;  4AZ9 A;  2IWL X;  2V6V A;  1XTN A;  1O7K A;  4PZG A;  2I4K A;  3HPB A;  2ETT A;  4HAS A;  2AR5 A;  2CSK A;  2V14 A;  1KQ6 A;  2DYB A;  4AKV A;  4IKB B;  3DYT A;  4IKD A;  1H6H A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4P2JA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations