4PQOA

Structure of the human snx14 px domain in space group i41
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
125
structure length
105
Chain Sequence
LAAWKISIPYVDFFEDIPVFCIDVERPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
pubmed doi rcsb
molecule tags Protein transport
source organism Homo sapiens
molecule keywords Sorting nexin-14
total genus 23
structure length 105
sequence length 125
ec nomenclature
pdb deposition date 2014-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4pqoA00
2ETTA 2REAA 2CZOA 4AKVA 3IQ2A 4P2IA 4IKDA 1XTEA 1XTNA 2DYBA 2V6VA 1H6HA 4PZGA 4IKBA 2RAJA 2RAIA 4ON3A 4P2JA 4BGJA 2IWLX 3HPCX 3P0CA 2I4KA 2CSKA 4AZ9A 2REDA 2RAKA 1KQ6A 3DYTA 1OCUA 3HPBA 3LUIA 2WWEA 4PQPA 2YPSA 1OCSA 2V14A 4IKBB 4PQOA 1KMDA 1O7KA 2L73A 2AR5A 3FOGA 4HASA 1GD5A 4OXWA
chains in the Genus database with same CATH superfamily
2ETTA 2REAA 2CZOA 4AKVA 3IQ2A 4P2IA 4IKDA 1XTEA 1XTNA 2DYBA 2V6VA 1H6HA 4PZGA 4IKBA 2RAJA 2RAIA 4ON3A 4P2JA 4BGJA 2IWLX 3HPCX 3P0CA 2I4KA 2CSKA 4AZ9A 2REDA 2RAKA 1KQ6A 3DYTA 1OCUA 3HPBA 3LUIA 2WWEA 4PQPA 2YPSA 1OCSA 2V14A 4IKBB 4PQOA 1KMDA 1O7KA 2L73A 2AR5A 3FOGA 4HASA 1GD5A 4OXWA
chains in the Genus database with same CATH topology
2ETTA 2REAA 2CZOA 4AKVA 3IQ2A 4P2IA 4IKDA 1XTEA 1XTNA 2DYBA 2V6VA 1H6HA 4PZGA 4IKBA 2RAJA 2RAIA 4ON3A 4P2JA 4BGJA 2IWLX 3HPCX 3P0CA 2I4KA 2CSKA 4AZ9A 2REDA 2RAKA 1KQ6A 3DYTA 1OCUA 3HPBA 3LUIA 2WWEA 4PQPA 2YPSA 1OCSA 2V14A 4IKBB 4PQOA 1KMDA 1O7KA 2L73A 2AR5A 3FOGA 4HASA 1GD5A 4OXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ETT A;  2REA A;  2CZO A;  4AKV A;  3IQ2 A;  4P2I A;  4IKD A;  1XTE A;  1XTN A;  2DYB A;  2V6V A;  1H6H A;  4PZG A;  4IKB A;  2RAJ A;  2RAI A;  4ON3 A;  4P2J A;  4BGJ A;  2IWL X;  3HPC X;  3P0C A;  2I4K A;  2CSK A;  4AZ9 A;  2RED A;  2RAK A;  1KQ6 A;  3DYT A;  1OCU A;  3HPB A;  3LUI A;  2WWE A;  4PQP A;  2YPS A;  1OCS A;  2V14 A;  4IKB B;  4PQO A;  1KMD A;  1O7K A;  2L73 A;  2AR5 A;  3FOG A;  4HAS A;  1GD5 A;  4OXW A; 
#chains in the Genus database with same CATH topology
 2ETT A;  2REA A;  2CZO A;  4AKV A;  3IQ2 A;  4P2I A;  4IKD A;  1XTE A;  1XTN A;  2DYB A;  2V6V A;  1H6H A;  4PZG A;  4IKB A;  2RAJ A;  2RAI A;  4ON3 A;  4P2J A;  4BGJ A;  2IWL X;  3HPC X;  3P0C A;  2I4K A;  2CSK A;  4AZ9 A;  2RED A;  2RAK A;  1KQ6 A;  3DYT A;  1OCU A;  3HPB A;  3LUI A;  2WWE A;  4PQP A;  2YPS A;  1OCS A;  2V14 A;  4IKB B;  4PQO A;  1KMD A;  1O7K A;  2L73 A;  2AR5 A;  3FOG A;  4HAS A;  1GD5 A;  4OXW A; 
#chains in the Genus database with same CATH homology
 2ETT A;  2REA A;  2CZO A;  4AKV A;  3IQ2 A;  4P2I A;  4IKD A;  1XTE A;  1XTN A;  2DYB A;  2V6V A;  1H6H A;  4PZG A;  4IKB A;  2RAJ A;  2RAI A;  4ON3 A;  4P2J A;  4BGJ A;  2IWL X;  3HPC X;  3P0C A;  2I4K A;  2CSK A;  4AZ9 A;  2RED A;  2RAK A;  1KQ6 A;  3DYT A;  1OCU A;  3HPB A;  3LUI A;  2WWE A;  4PQP A;  2YPS A;  1OCS A;  2V14 A;  4IKB B;  4PQO A;  1KMD A;  1O7K A;  2L73 A;  2AR5 A;  3FOG A;  4HAS A;  1GD5 A;  4OXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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