4PQO | Genus

Total Genus 23

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	23
sequence length	125
structure length	105
Chain Sequence	LAAWKISIPYVDFFEDIPVFCIDVERPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__911612696339609__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__911612696339609__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4PQO/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__911612696339609__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"911612696339609","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4PQO/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__911612696339609__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Protein transport
source organism	Homo sapiens
publication title	Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. pubmed doi rcsb
molecule keywords	Sorting nexin-14
total genus	23
structure length	105
sequence length	125
ec nomenclature
pdb deposition date	2014-03-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00787	PX	PX domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1520.10	Alpha Beta	2-Layer Sandwich	PX Domain	Phox-like domain	4pqoA00

3HPBA 4IKBA 1H6HA 2L73A 2RAKA 4PZGA 2WWEA 4ON3A 2REDA 4P2JA 4PQPA 2REAA 2I4KA 3P0CA 1XTEA 2YPSA 2IWLX 2RAIA 1GD5A 4P2IA 2DYBA 4AKVA 2RAJA 2ETTA 1KMDA 3HPCX 4AZ9A 3LUIA 1OCUA 4IKBB 4IKDA 2V14A 4PQOA 4BGJA 2V6VA 1OCSA 1O7KA 3IQ2A 1KQ6A 3DYTA 3FOGA 2CSKA 4OXWA 2CZOA 2AR5A 4HASA 1XTNA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3HPB A;  4IKB A;  1H6H A;  2L73 A;  2RAK A;  4PZG A;  2WWE A;  4ON3 A;  2RED A;  4P2J A;  4PQP A;  2REA A;  2I4K A;  3P0C A;  1XTE A;  2YPS A;  2IWL X;  2RAI A;  1GD5 A;  4P2I A;  2DYB A;  4AKV A;  2RAJ A;  2ETT A;  1KMD A;  3HPC X;  4AZ9 A;  3LUI A;  1OCU A;  4IKB B;  4IKD A;  2V14 A;  4PQO A;  4BGJ A;  2V6V A;  1OCS A;  1O7K A;  3IQ2 A;  1KQ6 A;  3DYT A;  3FOG A;  2CSK A;  4OXW A;  2CZO A;  2AR5 A;  4HAS A;  1XTN A; 
#chains in the Genus database with same CATH topology
 3HPB A;  4IKB A;  1H6H A;  2L73 A;  2RAK A;  4PZG A;  2WWE A;  4ON3 A;  2RED A;  4P2J A;  4PQP A;  2REA A;  2I4K A;  3P0C A;  1XTE A;  2YPS A;  2IWL X;  2RAI A;  1GD5 A;  4P2I A;  2DYB A;  4AKV A;  2RAJ A;  2ETT A;  1KMD A;  3HPC X;  4AZ9 A;  3LUI A;  1OCU A;  4IKB B;  4IKD A;  2V14 A;  4PQO A;  4BGJ A;  2V6V A;  1OCS A;  1O7K A;  3IQ2 A;  1KQ6 A;  3DYT A;  3FOG A;  2CSK A;  4OXW A;  2CZO A;  2AR5 A;  4HAS A;  1XTN A; 
#chains in the Genus database with same CATH homology
 3HPB A;  4IKB A;  1H6H A;  2L73 A;  2RAK A;  4PZG A;  2WWE A;  4ON3 A;  2RED A;  4P2J A;  4PQP A;  2REA A;  2I4K A;  3P0C A;  1XTE A;  2YPS A;  2IWL X;  2RAI A;  1GD5 A;  4P2I A;  2DYB A;  4AKV A;  2RAJ A;  2ETT A;  1KMD A;  3HPC X;  4AZ9 A;  3LUI A;  1OCU A;  4IKB B;  4IKD A;  2V14 A;  4PQO A;  4BGJ A;  2V6V A;  1OCS A;  1O7K A;  3IQ2 A;  1KQ6 A;  3DYT A;  3FOG A;  2CSK A;  4OXW A;  2CZO A;  2AR5 A;  4HAS A;  1XTN A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4PQOA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations