4WQOC

Structure of vhl-elob-eloc-cul2
Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
96
structure length
96
Chain Sequence
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTIV1 (47-50)TIV2 (48-51)S1 (18-22)TI1 (23-26)S2 (28-32)AH2 (40-46)TVIII1 (37-40)TIV3 (50-53)TIV4 (52-55)TII1 (83-86)S3 (59-61)AH3 (67-83)TI2 (62-65)Updating...
connected with : NaN
molecule tags Transcription
source organism Homo sapiens
publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
molecule keywords Von Hippel-Lindau disease tumor suppressor
total genus 27
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2014-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03931 Skp1_POZ Skp1 family, tetramerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 4wqoC00
2NZ0B 1QDWA 5BXBA 3M52A 3DRZA 1A68A 4APFA 2P1NA 4W9LB 5FTAA 1T1DA 3LBZA 3B84A 3LUTB 2VKPA 2ASSA 4CP3A 1NEXA 3HU6A 2Z8HA 2P1MA 5LLIB 2PPIA 5HZGC 2P1PA 2ASTA 4W9GB 3BIMA 4U2NA 3ZRFB 4AP2A 1EODA 1VCBB 4I6JC 5HYWB 1S1GA 4J8ZA 4AJYC 2VPKA 1LDKD 3HVEA 3KVTA 1FQVB 4UIJA 4BGCA 2NN2A 3V7DA 2MA9C 3HQIA 3OGKA 3ZTCB 4U77A 2OVRA 5H7HA 2YY9A 3I3NA 5EUPA 3ZKJB 3ZTDB 4W9HB 5JH5B 4B95B 4WQOC 1R29A 3ZUNB 5BXHA 4U2MA 2I2RA 2A79B 2IHCA 3OGLA 2FNJC 3C6PA 4ZOUA 5A15A 3OHVA 3OGMA 3FKCA 3WSOB 2C9WC 3M4TA 2E31B 2IZVC 1LQBB 3ZNGB 4JGHC 4HXIA 4W9EB 1R28A 3C6OA 3DCGB 4W9DB 3HTMA 2OVPA 1FS2B 4CXTA 2R9RB 1FS1B 5A6RA 4EOZA 4JTAB 3C6NA 2P1OA 5BO4C 3L2OA 1EOFA 2IF5A 3OHUA 1LM8C 4W9IB 4UYIA 4CXIA 4W9CB 2JZ3C 3E4UA 4W9HH 1EOEA 4B9KE 4B9KB 4JTCB 3LNMB 3M8VA 3MKSA 4AWJB 5DADA 3ZRCB 5BXDA 2P1QA 2OVQA 4W9JB 5DAFA 1CS3A 3GA1A 5IBKA 1DSXA 3M5BA 1EXBE 4W9KB 1P22B 4BKSB 4BKTB 1R2BA 3HVEB 4JTDB 1QDVA 1BUOA 4CRHA 1NN7A 4W9FB 2E32B 2Q81A 4CXJA 1HV2A 5H7GA 4N9F5
chains in the Genus database with same CATH superfamily
2NZ0B 1QDWA 5BXBA 3M52A 3DRZA 4YY8A 1A68A 4APFA 2P1NA 4W9LB 5FTAA 1T1DA 3LBZA 3B84A 3LUTB 2VKPA 2ASSA 4CP3A 1NEXA 3HU6A 2Z8HA 2P1MA 5LLIB 2PPIA 5HZGC 2P1PA 2ASTA 4W9GB 3BIMA 4U2NA 3ZRFB 4AP2A 1EODA 1VCBB 4I6JC 5HYWB 1S1GA 4J8ZA 4AJYC 2VPKA 1LDKD 3HVEA 3KVTA 1FQVB 4UIJA 4BGCA 2NN2A 3V7DA 2MA9C 3HQIA 3DRXA 3OGKA 3ZTCB 4U77A 2OVRA 5H7HA 2YY9A 3I3NA 5EUPA 3ZKJB 3ZTDB 4W9HB 5JH5B 4B95B 4WQOC 1R29A 3ZUNB 5BXHA 4U2MA 2I2RA 2A79B 2IHCA 3OGLA 2FNJC 3C6PA 4ZOUA 5A15A 3OHVA 3OGMA 3FKCA 3WSOB 2C9WC 3M4TA 2E31B 2IZVC 1LQBB 3ZNGB 4JGHC 4HXIA 4W9EB 1R28A 3C6OA 3DCGB 4W9DB 3HTMA 2OVPA 1FS2B 4CXTA 2R9RB 1FS1B 5A6RA 4EOZA 4JTAB 3C6NA 2P1OA 5BO4C 3L2OA 1EOFA 2IF5A 3OHUA 1LM8C 4W9IB 4UYIA 4CXIA 4W9CB 2JZ3C 3E4UA 4W9HH 1EOEA 4B9KE 4B9KB 4JTCB 3LNMB 3M8VA 3MKSA 4AWJB 5DADA 3ZRCB 5BXDA 3DRYA 4ZGCA 2P1QA 2OVQA 4W9JB 5DAFA 1CS3A 3GA1A 5IBKA 1DSXA 3M5BA 1EXBE 4W9KB 1P22B 4BKSB 4BKTB 1R2BA 3HVEB 4JTDB 1QDVA 1BUOA 4CRHA 1NN7A 4W9FB 2E32B 2Q81A 4CXJA 1HV2A 5H7GA 4N9F5
chains in the Genus database with same CATH topology
2NZ0B 1QDWA 5BXBA 3M52A 3DRZA 4YY8A 1A68A 4APFA 2P1NA 4W9LB 5FTAA 1T1DA 3LBZA 3B84A 3LUTB 2VKPA 2ASSA 4CP3A 1NEXA 3HU6A 2Z8HA 2P1MA 5LLIB 2PPIA 5HZGC 2P1PA 2ASTA 4W9GB 3BIMA 4U2NA 3ZRFB 4AP2A 1EODA 1VCBB 4I6JC 5HYWB 1S1GA 4J8ZA 4AJYC 2VPKA 1LDKD 3HVEA 3KVTA 1FQVB 4UIJA 4BGCA 2NN2A 3V7DA 2MA9C 3HQIA 3DRXA 3OGKA 3ZTCB 4U77A 2OVRA 5H7HA 2YY9A 3I3NA 5EUPA 3ZKJB 3ZTDB 4W9HB 5JH5B 4B95B 4WQOC 1R29A 3ZUNB 5BXHA 4U2MA 2I2RA 2A79B 2IHCA 3OGLA 2FNJC 3C6PA 4ZOUA 5A15A 3OHVA 3OGMA 3FKCA 3WSOB 2C9WC 3M4TA 2E31B 2IZVC 1LQBB 3ZNGB 4JGHC 4HXIA 4W9EB 1R28A 3C6OA 3DCGB 4W9DB 3HTMA 2OVPA 1FS2B 4CXTA 2R9RB 1FS1B 5A6RA 4EOZA 4JTAB 3C6NA 2P1OA 5BO4C 3L2OA 1EOFA 2IF5A 3OHUA 1LM8C 4W9IB 4UYIA 4CXIA 4W9CB 2JZ3C 3E4UA 4W9HH 1EOEA 4B9KE 4B9KB 4JTCB 3LNMB 3M8VA 3MKSA 4AWJB 5DADA 3ZRCB 5BXDA 3DRYA 4ZGCA 2P1QA 2OVQA 4W9JB 5DAFA 1CS3A 3GA1A 5IBKA 1DSXA 3M5BA 1EXBE 4W9KB 1P22B 4BKSB 4BKTB 1R2BA 3HVEB 4JTDB 1QDVA 1BUOA 4CRHA 1NN7A 4W9FB 2E32B 2Q81A 4CXJA 1HV2A 5H7GA 4N9F5
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2NZ0 B;  1QDW A;  5BXB A;  3M52 A;  3DRZ A;  1A68 A;  4APF A;  2P1N A;  4W9L B;  5FTA A;  1T1D A;  3LBZ A;  3B84 A;  3LUT B;  2VKP A;  2ASS A;  4CP3 A;  1NEX A;  3HU6 A;  2Z8H A;  2P1M A;  5LLI B;  2PPI A;  5HZG C;  2P1P A;  2AST A;  4W9G B;  3BIM A;  4U2N A;  3ZRF B;  4AP2 A;  1EOD A;  1VCB B;  4I6J C;  5HYW B;  1S1G A;  4J8Z A;  4AJY C;  2VPK A;  1LDK D;  3HVE A;  3KVT A;  1FQV B;  4UIJ A;  4BGC A;  2NN2 A;  3V7D A;  2MA9 C;  3HQI A;  3OGK A;  3ZTC B;  4U77 A;  2OVR A;  5H7H A;  2YY9 A;  3I3N A;  5EUP A;  3ZKJ B;  3ZTD B;  4W9H B;  5JH5 B;  4B95 B;  4WQO C;  1R29 A;  3ZUN B;  5BXH A;  4U2M A;  2I2R A;  2A79 B;  2IHC A;  3OGL A;  2FNJ C;  3C6P A;  4ZOU A;  5A15 A;  3OHV A;  3OGM A;  3FKC A;  3WSO B;  2C9W C;  3M4T A;  2E31 B;  2IZV C;  1LQB B;  3ZNG B;  4JGH C;  4HXI A;  4W9E B;  1R28 A;  3C6O A;  3DCG B;  4W9D B;  3HTM A;  2OVP A;  1FS2 B;  4CXT A;  2R9R B;  1FS1 B;  5A6R A;  4EOZ A;  4JTA B;  3C6N A;  2P1O A;  5BO4 C;  3L2O A;  1EOF A;  2IF5 A;  3OHU A;  1LM8 C;  4W9I B;  4UYI A;  4CXI A;  4W9C B;  2JZ3 C;  3E4U A;  4W9H H;  1EOE A;  4B9K E;  4B9K B;  4JTC B;  3LNM B;  3M8V A;  3MKS A;  4AWJ B;  5DAD A;  3ZRC B;  5BXD A;  2P1Q A;  2OVQ A;  4W9J B;  5DAF A;  1CS3 A;  3GA1 A;  5IBK A;  1DSX A;  3M5B A;  1EXB E;  4W9K B;  1P22 B;  4BKS B;  4BKT B;  1R2B A;  3HVE B;  4JTD B;  1QDV A;  1BUO A;  4CRH A;  1NN7 A;  4W9F B;  2E32 B;  2Q81 A;  4CXJ A;  1HV2 A;  5H7G A;  4N9F 5; 
#chains in the Genus database with same CATH topology
 2NZ0 B;  1QDW A;  5BXB A;  3M52 A;  3DRZ A;  4YY8 A;  1A68 A;  4APF A;  2P1N A;  4W9L B;  5FTA A;  1T1D A;  3LBZ A;  3B84 A;  3LUT B;  2VKP A;  2ASS A;  4CP3 A;  1NEX A;  3HU6 A;  2Z8H A;  2P1M A;  5LLI B;  2PPI A;  5HZG C;  2P1P A;  2AST A;  4W9G B;  3BIM A;  4U2N A;  3ZRF B;  4AP2 A;  1EOD A;  1VCB B;  4I6J C;  5HYW B;  1S1G A;  4J8Z A;  4AJY C;  2VPK A;  1LDK D;  3HVE A;  3KVT A;  1FQV B;  4UIJ A;  4BGC A;  2NN2 A;  3V7D A;  2MA9 C;  3HQI A;  3DRX A;  3OGK A;  3ZTC B;  4U77 A;  2OVR A;  5H7H A;  2YY9 A;  3I3N A;  5EUP A;  3ZKJ B;  3ZTD B;  4W9H B;  5JH5 B;  4B95 B;  4WQO C;  1R29 A;  3ZUN B;  5BXH A;  4U2M A;  2I2R A;  2A79 B;  2IHC A;  3OGL A;  2FNJ C;  3C6P A;  4ZOU A;  5A15 A;  3OHV A;  3OGM A;  3FKC A;  3WSO B;  2C9W C;  3M4T A;  2E31 B;  2IZV C;  1LQB B;  3ZNG B;  4JGH C;  4HXI A;  4W9E B;  1R28 A;  3C6O A;  3DCG B;  4W9D B;  3HTM A;  2OVP A;  1FS2 B;  4CXT A;  2R9R B;  1FS1 B;  5A6R A;  4EOZ A;  4JTA B;  3C6N A;  2P1O A;  5BO4 C;  3L2O A;  1EOF A;  2IF5 A;  3OHU A;  1LM8 C;  4W9I B;  4UYI A;  4CXI A;  4W9C B;  2JZ3 C;  3E4U A;  4W9H H;  1EOE A;  4B9K E;  4B9K B;  4JTC B;  3LNM B;  3M8V A;  3MKS A;  4AWJ B;  5DAD A;  3ZRC B;  5BXD A;  3DRY A;  4ZGC A;  2P1Q A;  2OVQ A;  4W9J B;  5DAF A;  1CS3 A;  3GA1 A;  5IBK A;  1DSX A;  3M5B A;  1EXB E;  4W9K B;  1P22 B;  4BKS B;  4BKT B;  1R2B A;  3HVE B;  4JTD B;  1QDV A;  1BUO A;  4CRH A;  1NN7 A;  4W9F B;  2E32 B;  2Q81 A;  4CXJ A;  1HV2 A;  5H7G A;  4N9F 5; 
#chains in the Genus database with same CATH homology
 2NZ0 B;  1QDW A;  5BXB A;  3M52 A;  3DRZ A;  4YY8 A;  1A68 A;  4APF A;  2P1N A;  4W9L B;  5FTA A;  1T1D A;  3LBZ A;  3B84 A;  3LUT B;  2VKP A;  2ASS A;  4CP3 A;  1NEX A;  3HU6 A;  2Z8H A;  2P1M A;  5LLI B;  2PPI A;  5HZG C;  2P1P A;  2AST A;  4W9G B;  3BIM A;  4U2N A;  3ZRF B;  4AP2 A;  1EOD A;  1VCB B;  4I6J C;  5HYW B;  1S1G A;  4J8Z A;  4AJY C;  2VPK A;  1LDK D;  3HVE A;  3KVT A;  1FQV B;  4UIJ A;  4BGC A;  2NN2 A;  3V7D A;  2MA9 C;  3HQI A;  3DRX A;  3OGK A;  3ZTC B;  4U77 A;  2OVR A;  5H7H A;  2YY9 A;  3I3N A;  5EUP A;  3ZKJ B;  3ZTD B;  4W9H B;  5JH5 B;  4B95 B;  4WQO C;  1R29 A;  3ZUN B;  5BXH A;  4U2M A;  2I2R A;  2A79 B;  2IHC A;  3OGL A;  2FNJ C;  3C6P A;  4ZOU A;  5A15 A;  3OHV A;  3OGM A;  3FKC A;  3WSO B;  2C9W C;  3M4T A;  2E31 B;  2IZV C;  1LQB B;  3ZNG B;  4JGH C;  4HXI A;  4W9E B;  1R28 A;  3C6O A;  3DCG B;  4W9D B;  3HTM A;  2OVP A;  1FS2 B;  4CXT A;  2R9R B;  1FS1 B;  5A6R A;  4EOZ A;  4JTA B;  3C6N A;  2P1O A;  5BO4 C;  3L2O A;  1EOF A;  2IF5 A;  3OHU A;  1LM8 C;  4W9I B;  4UYI A;  4CXI A;  4W9C B;  2JZ3 C;  3E4U A;  4W9H H;  1EOE A;  4B9K E;  4B9K B;  4JTC B;  3LNM B;  3M8V A;  3MKS A;  4AWJ B;  5DAD A;  3ZRC B;  5BXD A;  3DRY A;  4ZGC A;  2P1Q A;  2OVQ A;  4W9J B;  5DAF A;  1CS3 A;  3GA1 A;  5IBK A;  1DSX A;  3M5B A;  1EXB E;  4W9K B;  1P22 B;  4BKS B;  4BKT B;  1R2B A;  3HVE B;  4JTD B;  1QDV A;  1BUO A;  4CRH A;  1NN7 A;  4W9F B;  2E32 B;  2Q81 A;  4CXJ A;  1HV2 A;  5H7G A;  4N9F 5;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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