5DAD | Genus

Total Genus 36

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	36
sequence length	130
structure length	123
Chain Sequence	RTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transcription
source organism	Homo sapiens
publication title	Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding. pubmed doi rcsb
molecule keywords	Kelch-like ECH-associated protein 1
total genus	36
structure length	123
sequence length	130
ec nomenclature
pdb deposition date	2015-08-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00651	BTB	BTB/POZ domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	5dadA00

1FS1B 1BUOA 2NZ0B 3C6NA 4W9LB 1QDWA 4BKSB 3FKCA 5EUPA 3HU6A 1EOFA 2E31B 2I2RA 3ZRFB 5LLIB 1FS2B 3ZTDB 3MKSA 1R28A 2Q81A 2PPIA 3BIMA 4JTAB 2IZVC 4W9GB 5A15A 1HV2A 5H7GA 4AJYC 1FQVB 3OGMA 1DSXA 5BXBA 2VKPA 2Z8HA 4CRHA 3LBZA 4APFA 2IHCA 1NEXA 4EOZA 1R2BA 1QDVA 4W9IB 5HZGC 2NN2A 3HVEA 4W9EB 3HVEB 4CXJA 2JZ3C 1EXBE 3M52A 3C6PA 3DRZA 4JTCB 3GA1A 4JGHC 5FTAA 4W9DB 2C9WC 2P1OA 4AP2A 1T1DA 1S1GA 3ZRCB 3ZKJB 4B95B 4JTDB 4U77A 4N9F5 3OHVA 1LM8C 4CXTA 2P1NA 3WSOB 4CP3A 5BXHA 4W9HH 2R9RB 4UIJA 3ZUNB 5BXDA 2FNJC 5JH5B 2P1MA 2ASTA 4W9JB 1EODA 3V7DA 4BGCA 2A79B 2OVPA 1P22B 3HQIA 3C6OA 3M5BA 4W9KB 1LDKD 1LQBB 3E4UA 3OHUA 5BO4C 4W9CB 4AWJB 5HYWB 3M8VA 1R29A 4BKTB 3M4TA 3OGLA 4W9HB 1NN7A 5IBKA 1VCBB 2E32B 3OGKA 4B9KE 5H7HA 2P1QA 1CS3A 4J8ZA 2IF5A 4W9FB 5DAFA 3KVTA 2ASSA 3DCGB 3I3NA 3ZTCB 3ZNGB 4B9KB 4WQOC 4U2NA 2MA9C 5A6RA 4UYIA 3LUTB 2OVRA 2OVQA 4ZOUA 3L2OA 3LNMB 5DADA 4HXIA 1A68A 2YY9A 4CXIA 1EOEA 3B84A 2VPKA 2P1PA 3HTMA 4I6JC 4U2MA
chains in the Genus database with same CATH superfamily

1FS1B 1BUOA 4ZGCA 2NZ0B 3C6NA 4W9LB 1QDWA 4BKSB 3FKCA 5EUPA 3HU6A 1EOFA 2E31B 2I2RA 3ZRFB 5LLIB 1FS2B 3ZTDB 3MKSA 1R28A 2Q81A 2PPIA 3BIMA 4JTAB 2IZVC 4W9GB 5A15A 1HV2A 5H7GA 4AJYC 1FQVB 3OGMA 1DSXA 5BXBA 2VKPA 2Z8HA 4CRHA 3LBZA 4APFA 2IHCA 1NEXA 4EOZA 1R2BA 1QDVA 4W9IB 5HZGC 2NN2A 3HVEA 4W9EB 3HVEB 4CXJA 2JZ3C 1EXBE 3M52A 3C6PA 3DRZA 4JTCB 3GA1A 4JGHC 5FTAA 4W9DB 2C9WC 2P1OA 4AP2A 1T1DA 1S1GA 3ZRCB 3ZKJB 4B95B 4JTDB 4U77A 4N9F5 3OHVA 1LM8C 4CXTA 2P1NA 3WSOB 4CP3A 5BXHA 4W9HH 2R9RB 4UIJA 4YY8A 3ZUNB 5BXDA 2FNJC 5JH5B 2P1MA 2ASTA 4W9JB 1EODA 3V7DA 4BGCA 2A79B 2OVPA 1P22B 3HQIA 3C6OA 3M5BA 4W9KB 1LDKD 1LQBB 3E4UA 3OHUA 5BO4C 4W9CB 4AWJB 5HYWB 3M8VA 1R29A 4BKTB 3M4TA 3OGLA 4W9HB 1NN7A 5IBKA 3DRYA 1VCBB 2E32B 3OGKA 4B9KE 5H7HA 2P1QA 1CS3A 4J8ZA 2IF5A 4W9FB 5DAFA 3KVTA 2ASSA 3DCGB 3I3NA 3ZTCB 3ZNGB 4B9KB 4WQOC 4U2NA 2MA9C 5A6RA 4UYIA 3LUTB 2OVRA 2OVQA 4ZOUA 3DRXA 3L2OA 3LNMB 4HXIA 5DADA 1A68A 2YY9A 4CXIA 1EOEA 3B84A 2VPKA 2P1PA 3HTMA 4I6JC 4U2MA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1FS1 B;  1BUO A;  2NZ0 B;  3C6N A;  4W9L B;  1QDW A;  4BKS B;  3FKC A;  5EUP A;  3HU6 A;  1EOF A;  2E31 B;  2I2R A;  3ZRF B;  5LLI B;  1FS2 B;  3ZTD B;  3MKS A;  1R28 A;  2Q81 A;  2PPI A;  3BIM A;  4JTA B;  2IZV C;  4W9G B;  5A15 A;  1HV2 A;  5H7G A;  4AJY C;  1FQV B;  3OGM A;  1DSX A;  5BXB A;  2VKP A;  2Z8H A;  4CRH A;  3LBZ A;  4APF A;  2IHC A;  1NEX A;  4EOZ A;  1R2B A;  1QDV A;  4W9I B;  5HZG C;  2NN2 A;  3HVE A;  4W9E B;  3HVE B;  4CXJ A;  2JZ3 C;  1EXB E;  3M52 A;  3C6P A;  3DRZ A;  4JTC B;  3GA1 A;  4JGH C;  5FTA A;  4W9D B;  2C9W C;  2P1O A;  4AP2 A;  1T1D A;  1S1G A;  3ZRC B;  3ZKJ B;  4B95 B;  4JTD B;  4U77 A;  4N9F 5;  3OHV A;  1LM8 C;  4CXT A;  2P1N A;  3WSO B;  4CP3 A;  5BXH A;  4W9H H;  2R9R B;  4UIJ A;  3ZUN B;  5BXD A;  2FNJ C;  5JH5 B;  2P1M A;  2AST A;  4W9J B;  1EOD A;  3V7D A;  4BGC A;  2A79 B;  2OVP A;  1P22 B;  3HQI A;  3C6O A;  3M5B A;  4W9K B;  1LDK D;  1LQB B;  3E4U A;  3OHU A;  5BO4 C;  4W9C B;  4AWJ B;  5HYW B;  3M8V A;  1R29 A;  4BKT B;  3M4T A;  3OGL A;  4W9H B;  1NN7 A;  5IBK A;  1VCB B;  2E32 B;  3OGK A;  4B9K E;  5H7H A;  2P1Q A;  1CS3 A;  4J8Z A;  2IF5 A;  4W9F B;  5DAF A;  3KVT A;  2ASS A;  3DCG B;  3I3N A;  3ZTC B;  3ZNG B;  4B9K B;  4WQO C;  4U2N A;  2MA9 C;  5A6R A;  4UYI A;  3LUT B;  2OVR A;  2OVQ A;  4ZOU A;  3L2O A;  3LNM B;  5DAD A;  4HXI A;  1A68 A;  2YY9 A;  4CXI A;  1EOE A;  3B84 A;  2VPK A;  2P1P A;  3HTM A;  4I6J C;  4U2M A; 
#chains in the Genus database with same CATH topology
 1FS1 B;  1BUO A;  4ZGC A;  2NZ0 B;  3C6N A;  4W9L B;  1QDW A;  4BKS B;  3FKC A;  5EUP A;  3HU6 A;  1EOF A;  2E31 B;  2I2R A;  3ZRF B;  5LLI B;  1FS2 B;  3ZTD B;  3MKS A;  1R28 A;  2Q81 A;  2PPI A;  3BIM A;  4JTA B;  2IZV C;  4W9G B;  5A15 A;  1HV2 A;  5H7G A;  4AJY C;  1FQV B;  3OGM A;  1DSX A;  5BXB A;  2VKP A;  2Z8H A;  4CRH A;  3LBZ A;  4APF A;  2IHC A;  1NEX A;  4EOZ A;  1R2B A;  1QDV A;  4W9I B;  5HZG C;  2NN2 A;  3HVE A;  4W9E B;  3HVE B;  4CXJ A;  2JZ3 C;  1EXB E;  3M52 A;  3C6P A;  3DRZ A;  4JTC B;  3GA1 A;  4JGH C;  5FTA A;  4W9D B;  2C9W C;  2P1O A;  4AP2 A;  1T1D A;  1S1G A;  3ZRC B;  3ZKJ B;  4B95 B;  4JTD B;  4U77 A;  4N9F 5;  3OHV A;  1LM8 C;  4CXT A;  2P1N A;  3WSO B;  4CP3 A;  5BXH A;  4W9H H;  2R9R B;  4UIJ A;  4YY8 A;  3ZUN B;  5BXD A;  2FNJ C;  5JH5 B;  2P1M A;  2AST A;  4W9J B;  1EOD A;  3V7D A;  4BGC A;  2A79 B;  2OVP A;  1P22 B;  3HQI A;  3C6O A;  3M5B A;  4W9K B;  1LDK D;  1LQB B;  3E4U A;  3OHU A;  5BO4 C;  4W9C B;  4AWJ B;  5HYW B;  3M8V A;  1R29 A;  4BKT B;  3M4T A;  3OGL A;  4W9H B;  1NN7 A;  5IBK A;  3DRY A;  1VCB B;  2E32 B;  3OGK A;  4B9K E;  5H7H A;  2P1Q A;  1CS3 A;  4J8Z A;  2IF5 A;  4W9F B;  5DAF A;  3KVT A;  2ASS A;  3DCG B;  3I3N A;  3ZTC B;  3ZNG B;  4B9K B;  4WQO C;  4U2N A;  2MA9 C;  5A6R A;  4UYI A;  3LUT B;  2OVR A;  2OVQ A;  4ZOU A;  3DRX A;  3L2O A;  3LNM B;  4HXI A;  5DAD A;  1A68 A;  2YY9 A;  4CXI A;  1EOE A;  3B84 A;  2VPK A;  2P1P A;  3HTM A;  4I6J C;  4U2M A; 
#chains in the Genus database with same CATH homology
 1FS1 B;  1BUO A;  4ZGC A;  2NZ0 B;  3C6N A;  4W9L B;  1QDW A;  4BKS B;  3FKC A;  5EUP A;  3HU6 A;  1EOF A;  2E31 B;  2I2R A;  3ZRF B;  5LLI B;  1FS2 B;  3ZTD B;  3MKS A;  1R28 A;  2Q81 A;  2PPI A;  3BIM A;  4JTA B;  2IZV C;  4W9G B;  5A15 A;  1HV2 A;  5H7G A;  4AJY C;  1FQV B;  3OGM A;  1DSX A;  5BXB A;  2VKP A;  2Z8H A;  4CRH A;  3LBZ A;  4APF A;  2IHC A;  1NEX A;  4EOZ A;  1R2B A;  1QDV A;  4W9I B;  5HZG C;  2NN2 A;  3HVE A;  4W9E B;  3HVE B;  4CXJ A;  2JZ3 C;  1EXB E;  3M52 A;  3C6P A;  3DRZ A;  4JTC B;  3GA1 A;  4JGH C;  5FTA A;  4W9D B;  2C9W C;  2P1O A;  4AP2 A;  1T1D A;  1S1G A;  3ZRC B;  3ZKJ B;  4B95 B;  4JTD B;  4U77 A;  4N9F 5;  3OHV A;  1LM8 C;  4CXT A;  2P1N A;  3WSO B;  4CP3 A;  5BXH A;  4W9H H;  2R9R B;  4UIJ A;  4YY8 A;  3ZUN B;  5BXD A;  2FNJ C;  5JH5 B;  2P1M A;  2AST A;  4W9J B;  1EOD A;  3V7D A;  4BGC A;  2A79 B;  2OVP A;  1P22 B;  3HQI A;  3C6O A;  3M5B A;  4W9K B;  1LDK D;  1LQB B;  3E4U A;  3OHU A;  5BO4 C;  4W9C B;  4AWJ B;  5HYW B;  3M8V A;  1R29 A;  4BKT B;  3M4T A;  3OGL A;  4W9H B;  1NN7 A;  5IBK A;  3DRY A;  1VCB B;  2E32 B;  3OGK A;  4B9K E;  5H7H A;  2P1Q A;  1CS3 A;  4J8Z A;  2IF5 A;  4W9F B;  5DAF A;  3KVT A;  2ASS A;  3DCG B;  3I3N A;  3ZTC B;  3ZNG B;  4B9K B;  4WQO C;  4U2N A;  2MA9 C;  5A6R A;  4UYI A;  3LUT B;  2OVR A;  2OVQ A;  4ZOU A;  3DRX A;  3L2O A;  3LNM B;  4HXI A;  5DAD A;  1A68 A;  2YY9 A;  4CXI A;  1EOE A;  3B84 A;  2VPK A;  2P1P A;  3HTM A;  4I6J C;  4U2M A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5DADA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations