5H7GA

Crystal structure of the bcl6 btb domain in complex with f1324
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
122
structure length
122
Chain Sequence
SCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
pubmed doi rcsb
molecule tags Transcription/inhibitor
source organism Homo sapiens
molecule keywords B-cell lymphoma 6 protein
total genus 41
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 5h7gA00
4U77A 2R9RB 3LBZA 5H7HA 3GA1A 2E31B 2OVQA 5BXDA 4CP3A 1NEXA 5JH5B 4W9LB 3KVTA 3ZTCB 2JZ3C 3OHVA 2OVPA 4AJYC 3B84A 5IBKA 3MKSA 1S1GA 2VPKA 3BIMA 1P22B 1R28A 4U2MA 1FS1B 4HXIA 2YY9A 4BKSB 4BKTB 3OGKA 4W9GB 2E32B 2NZ0B 2I2RA 5HYWB 3I3NA 1LDKD 3M8VA 4AWJB 3ZUNB 2P1OA 1R29A 4JTDB 1LM8C 4JGHC 4CXTA 2P1QA 2VKPA 3ZRFB 4CXIA 2ASTA 3FKCA 3HVEA 4W9HH 4W9HB 3M5BA 5BO4C 1HV2A 4BGCA 2FNJC 3HVEB 3E4UA 4W9DB 3OHUA 1EOFA 5A6RA 4JTAB 1EXBE 2IHCA 3C6OA 2PPIA 4APFA 4UYIA 3OGLA 4CRHA 5DADA 3HQIA 4U2NA 1NN7A 2P1MA 2IZVC 3ZRCB 4B9KB 3WSOB 2P1PA 2ASSA 5BXBA 4B9KE 1BUOA 4J8ZA 1T1DA 2A79B 1R2BA 2Z8HA 4EOZA 5BXHA 2IF5A 5H7GA 4W9CB 3ZTDB 3ZKJB 4AP2A 3C6NA 3M4TA 4ZOUA 4UIJA 2MA9C 5DAFA 4N9F5 2P1NA 1EODA 1LQBB 1VCBB 3ZNGB 4W9KB 4W9EB 5FTAA 1EOEA 2NN2A 4W9IB 4JTCB 1QDWA 3HTMA 3HU6A 3DCGB 3M52A 1FS2B 3LUTB 4W9JB 3DRZA 1QDVA 3OGMA 1CS3A 4W9FB 3C6PA 3LNMB 4B95B 4WQOC 4CXJA 5HZGC 2Q81A 3L2OA 5EUPA 5LLIB 1FQVB 2C9WC 5A15A 1DSXA 4I6JC 1A68A 3V7DA 2OVRA
chains in the Genus database with same CATH superfamily
4U77A 2R9RB 3LBZA 5H7HA 3GA1A 2E31B 2OVQA 5BXDA 4CP3A 1NEXA 5JH5B 4W9LB 3KVTA 3ZTCB 2JZ3C 3OHVA 2OVPA 4AJYC 3B84A 5IBKA 3MKSA 1S1GA 2VPKA 3BIMA 1P22B 1R28A 4U2MA 1FS1B 4HXIA 2YY9A 3DRYA 4BKSB 4BKTB 3OGKA 4W9GB 4YY8A 2E32B 2NZ0B 2I2RA 5HYWB 3I3NA 1LDKD 3M8VA 4AWJB 3ZUNB 2P1OA 1R29A 3DRXA 4JTDB 1LM8C 4JGHC 4CXTA 2P1QA 2VKPA 3ZRFB 4CXIA 2ASTA 3FKCA 3HVEA 4W9HH 4W9HB 3M5BA 5BO4C 1HV2A 4BGCA 2FNJC 3HVEB 3E4UA 4W9DB 3OHUA 1EOFA 5A6RA 4JTAB 1EXBE 2IHCA 3C6OA 2PPIA 4APFA 4UYIA 3OGLA 4CRHA 5DADA 3HQIA 4U2NA 1NN7A 2P1MA 2IZVC 3ZRCB 4B9KB 3WSOB 2P1PA 2ASSA 5BXBA 4B9KE 1BUOA 4J8ZA 1T1DA 2A79B 1R2BA 2Z8HA 4EOZA 5BXHA 2IF5A 5H7GA 4W9CB 3ZTDB 3ZKJB 4AP2A 3C6NA 3M4TA 4ZOUA 4UIJA 2MA9C 5DAFA 4N9F5 2P1NA 1EODA 1LQBB 1VCBB 3ZNGB 4W9KB 4W9EB 5FTAA 1EOEA 2NN2A 4W9IB 4JTCB 1QDWA 3HTMA 3HU6A 3DCGB 3M52A 1FS2B 3LUTB 4W9JB 3DRZA 1QDVA 3OGMA 1CS3A 4W9FB 3C6PA 3LNMB 4B95B 4WQOC 4CXJA 5HZGC 2Q81A 4ZGCA 3L2OA 5EUPA 5LLIB 1FQVB 2C9WC 5A15A 1DSXA 4I6JC 1A68A 3V7DA 2OVRA
chains in the Genus database with same CATH topology
4U77A 2R9RB 3LBZA 5H7HA 3GA1A 2E31B 2OVQA 5BXDA 4CP3A 1NEXA 5JH5B 4W9LB 3KVTA 3ZTCB 2JZ3C 3OHVA 2OVPA 4AJYC 3B84A 5IBKA 3MKSA 1S1GA 2VPKA 3BIMA 1P22B 1R28A 4U2MA 1FS1B 4HXIA 2YY9A 3DRYA 4BKSB 4BKTB 3OGKA 4W9GB 4YY8A 2E32B 2NZ0B 2I2RA 5HYWB 3I3NA 1LDKD 3M8VA 4AWJB 3ZUNB 2P1OA 1R29A 3DRXA 4JTDB 1LM8C 4JGHC 4CXTA 2P1QA 2VKPA 3ZRFB 4CXIA 2ASTA 3FKCA 3HVEA 4W9HH 4W9HB 3M5BA 5BO4C 1HV2A 4BGCA 2FNJC 3HVEB 3E4UA 4W9DB 3OHUA 1EOFA 5A6RA 4JTAB 1EXBE 2IHCA 3C6OA 2PPIA 4APFA 4UYIA 3OGLA 4CRHA 5DADA 3HQIA 4U2NA 1NN7A 2P1MA 2IZVC 3ZRCB 4B9KB 3WSOB 2P1PA 2ASSA 5BXBA 4B9KE 1BUOA 4J8ZA 1T1DA 2A79B 1R2BA 2Z8HA 4EOZA 5BXHA 2IF5A 5H7GA 4W9CB 3ZTDB 3ZKJB 4AP2A 3C6NA 3M4TA 4ZOUA 4UIJA 2MA9C 5DAFA 4N9F5 2P1NA 1EODA 1LQBB 1VCBB 3ZNGB 4W9KB 4W9EB 5FTAA 1EOEA 2NN2A 4W9IB 4JTCB 1QDWA 3HTMA 3HU6A 3DCGB 3M52A 1FS2B 3LUTB 4W9JB 3DRZA 1QDVA 3OGMA 1CS3A 4W9FB 3C6PA 3LNMB 4B95B 4WQOC 4CXJA 5HZGC 2Q81A 4ZGCA 3L2OA 5EUPA 5LLIB 1FQVB 2C9WC 5A15A 1DSXA 4I6JC 1A68A 3V7DA 2OVRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U77 A;  2R9R B;  3LBZ A;  5H7H A;  3GA1 A;  2E31 B;  2OVQ A;  5BXD A;  4CP3 A;  1NEX A;  5JH5 B;  4W9L B;  3KVT A;  3ZTC B;  2JZ3 C;  3OHV A;  2OVP A;  4AJY C;  3B84 A;  5IBK A;  3MKS A;  1S1G A;  2VPK A;  3BIM A;  1P22 B;  1R28 A;  4U2M A;  1FS1 B;  4HXI A;  2YY9 A;  4BKS B;  4BKT B;  3OGK A;  4W9G B;  2E32 B;  2NZ0 B;  2I2R A;  5HYW B;  3I3N A;  1LDK D;  3M8V A;  4AWJ B;  3ZUN B;  2P1O A;  1R29 A;  4JTD B;  1LM8 C;  4JGH C;  4CXT A;  2P1Q A;  2VKP A;  3ZRF B;  4CXI A;  2AST A;  3FKC A;  3HVE A;  4W9H H;  4W9H B;  3M5B A;  5BO4 C;  1HV2 A;  4BGC A;  2FNJ C;  3HVE B;  3E4U A;  4W9D B;  3OHU A;  1EOF A;  5A6R A;  4JTA B;  1EXB E;  2IHC A;  3C6O A;  2PPI A;  4APF A;  4UYI A;  3OGL A;  4CRH A;  5DAD A;  3HQI A;  4U2N A;  1NN7 A;  2P1M A;  2IZV C;  3ZRC B;  4B9K B;  3WSO B;  2P1P A;  2ASS A;  5BXB A;  4B9K E;  1BUO A;  4J8Z A;  1T1D A;  2A79 B;  1R2B A;  2Z8H A;  4EOZ A;  5BXH A;  2IF5 A;  5H7G A;  4W9C B;  3ZTD B;  3ZKJ B;  4AP2 A;  3C6N A;  3M4T A;  4ZOU A;  4UIJ A;  2MA9 C;  5DAF A;  4N9F 5;  2P1N A;  1EOD A;  1LQB B;  1VCB B;  3ZNG B;  4W9K B;  4W9E B;  5FTA A;  1EOE A;  2NN2 A;  4W9I B;  4JTC B;  1QDW A;  3HTM A;  3HU6 A;  3DCG B;  3M52 A;  1FS2 B;  3LUT B;  4W9J B;  3DRZ A;  1QDV A;  3OGM A;  1CS3 A;  4W9F B;  3C6P A;  3LNM B;  4B95 B;  4WQO C;  4CXJ A;  5HZG C;  2Q81 A;  3L2O A;  5EUP A;  5LLI B;  1FQV B;  2C9W C;  5A15 A;  1DSX A;  4I6J C;  1A68 A;  3V7D A;  2OVR A; 
#chains in the Genus database with same CATH topology
 4U77 A;  2R9R B;  3LBZ A;  5H7H A;  3GA1 A;  2E31 B;  2OVQ A;  5BXD A;  4CP3 A;  1NEX A;  5JH5 B;  4W9L B;  3KVT A;  3ZTC B;  2JZ3 C;  3OHV A;  2OVP A;  4AJY C;  3B84 A;  5IBK A;  3MKS A;  1S1G A;  2VPK A;  3BIM A;  1P22 B;  1R28 A;  4U2M A;  1FS1 B;  4HXI A;  2YY9 A;  3DRY A;  4BKS B;  4BKT B;  3OGK A;  4W9G B;  4YY8 A;  2E32 B;  2NZ0 B;  2I2R A;  5HYW B;  3I3N A;  1LDK D;  3M8V A;  4AWJ B;  3ZUN B;  2P1O A;  1R29 A;  3DRX A;  4JTD B;  1LM8 C;  4JGH C;  4CXT A;  2P1Q A;  2VKP A;  3ZRF B;  4CXI A;  2AST A;  3FKC A;  3HVE A;  4W9H H;  4W9H B;  3M5B A;  5BO4 C;  1HV2 A;  4BGC A;  2FNJ C;  3HVE B;  3E4U A;  4W9D B;  3OHU A;  1EOF A;  5A6R A;  4JTA B;  1EXB E;  2IHC A;  3C6O A;  2PPI A;  4APF A;  4UYI A;  3OGL A;  4CRH A;  5DAD A;  3HQI A;  4U2N A;  1NN7 A;  2P1M A;  2IZV C;  3ZRC B;  4B9K B;  3WSO B;  2P1P A;  2ASS A;  5BXB A;  4B9K E;  1BUO A;  4J8Z A;  1T1D A;  2A79 B;  1R2B A;  2Z8H A;  4EOZ A;  5BXH A;  2IF5 A;  5H7G A;  4W9C B;  3ZTD B;  3ZKJ B;  4AP2 A;  3C6N A;  3M4T A;  4ZOU A;  4UIJ A;  2MA9 C;  5DAF A;  4N9F 5;  2P1N A;  1EOD A;  1LQB B;  1VCB B;  3ZNG B;  4W9K B;  4W9E B;  5FTA A;  1EOE A;  2NN2 A;  4W9I B;  4JTC B;  1QDW A;  3HTM A;  3HU6 A;  3DCG B;  3M52 A;  1FS2 B;  3LUT B;  4W9J B;  3DRZ A;  1QDV A;  3OGM A;  1CS3 A;  4W9F B;  3C6P A;  3LNM B;  4B95 B;  4WQO C;  4CXJ A;  5HZG C;  2Q81 A;  4ZGC A;  3L2O A;  5EUP A;  5LLI B;  1FQV B;  2C9W C;  5A15 A;  1DSX A;  4I6J C;  1A68 A;  3V7D A;  2OVR A; 
#chains in the Genus database with same CATH homology
 4U77 A;  2R9R B;  3LBZ A;  5H7H A;  3GA1 A;  2E31 B;  2OVQ A;  5BXD A;  4CP3 A;  1NEX A;  5JH5 B;  4W9L B;  3KVT A;  3ZTC B;  2JZ3 C;  3OHV A;  2OVP A;  4AJY C;  3B84 A;  5IBK A;  3MKS A;  1S1G A;  2VPK A;  3BIM A;  1P22 B;  1R28 A;  4U2M A;  1FS1 B;  4HXI A;  2YY9 A;  3DRY A;  4BKS B;  4BKT B;  3OGK A;  4W9G B;  4YY8 A;  2E32 B;  2NZ0 B;  2I2R A;  5HYW B;  3I3N A;  1LDK D;  3M8V A;  4AWJ B;  3ZUN B;  2P1O A;  1R29 A;  3DRX A;  4JTD B;  1LM8 C;  4JGH C;  4CXT A;  2P1Q A;  2VKP A;  3ZRF B;  4CXI A;  2AST A;  3FKC A;  3HVE A;  4W9H H;  4W9H B;  3M5B A;  5BO4 C;  1HV2 A;  4BGC A;  2FNJ C;  3HVE B;  3E4U A;  4W9D B;  3OHU A;  1EOF A;  5A6R A;  4JTA B;  1EXB E;  2IHC A;  3C6O A;  2PPI A;  4APF A;  4UYI A;  3OGL A;  4CRH A;  5DAD A;  3HQI A;  4U2N A;  1NN7 A;  2P1M A;  2IZV C;  3ZRC B;  4B9K B;  3WSO B;  2P1P A;  2ASS A;  5BXB A;  4B9K E;  1BUO A;  4J8Z A;  1T1D A;  2A79 B;  1R2B A;  2Z8H A;  4EOZ A;  5BXH A;  2IF5 A;  5H7G A;  4W9C B;  3ZTD B;  3ZKJ B;  4AP2 A;  3C6N A;  3M4T A;  4ZOU A;  4UIJ A;  2MA9 C;  5DAF A;  4N9F 5;  2P1N A;  1EOD A;  1LQB B;  1VCB B;  3ZNG B;  4W9K B;  4W9E B;  5FTA A;  1EOE A;  2NN2 A;  4W9I B;  4JTC B;  1QDW A;  3HTM A;  3HU6 A;  3DCG B;  3M52 A;  1FS2 B;  3LUT B;  4W9J B;  3DRZ A;  1QDV A;  3OGM A;  1CS3 A;  4W9F B;  3C6P A;  3LNM B;  4B95 B;  4WQO C;  4CXJ A;  5HZG C;  2Q81 A;  4ZGC A;  3L2O A;  5EUP A;  5LLI B;  1FQV B;  2C9W C;  5A15 A;  1DSX A;  4I6J C;  1A68 A;  3V7D A;  2OVR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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