5HS3A

Human thymidylate synthase complexed with dump and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
289
structure length
289
Chain Sequence
MPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Thymidylate synthase
total genus 95
structure length 289
sequence length 289
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.1.1.45: Thymidylate synthase.
pdb deposition date 2016-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00303 Thymidylat_synt Thymidylate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase; Chain A Thymidylate synthase/dCMP hydroxymethylase domain 5hs3A00
4DPDA 2G8DA 3BZ0A 4G2OX 4DQ1A 4FOGA 3N5EB 1CI7A 4GD7A 2VF0A 3NRRA 4GYHA 5H38A 2G8XA 1NJBA 1LCBA 3UM8A 1HVYA 3UWLB 1DDUA 5BY6A 1SYNA 1BKOA 4H0UA 1LCEA 4JEFA 3INVA 2FTQA 3UM5A 1BPJA 1JTUA 1TDAA 3ED7A 1EVGA 1JMIA 1JMHA 3HB8A 1AOBA 3EF9A 3BHRA 2FTOX 1F4FA 2TDMA 4Q0DA 5H39A 1QZFA 1KCEA 4O1XA 1F4GA 4FQSA 3CL9A 3IHIA 1I00A 1TLSA 3DG8C 1F4EA 5WRNA 4EB4A 2VETA 2FTNA 3BHLA 3EAWX 2TDDA 1TDCA 4O1XD 3H9KA 1B5EA 1BQ1A 4GEVA 3I3RA 3EDWX 1AJMA 3GG5A 4ISWA 4KYAA 1NCEA 1VZEA 3OB7A 1VZAA 1TSLA 2KCEA 2G89A 1VZCA 2G86A 3IROA 2OIPA 3IRNA 4H1IA 1F28A 4KNZA 1QQQA 3B5BA 3QGTA 1TVVA 1JUTA 2RDAA 3IRMA 1TRGA 1BO8A 3GH2X 3N5EA 4XSEA 1BP0A 1BIDA 1NJEA 1TSXA 4Q0EA 4FOXA 1JU6A 3EHIX 1B5DA 1TVUA 3C0AA 3DL6A 2ONBA 1NJAA 1TJSA 1JG0A 1F4DA 5J7WA 3GH0A 3DL5A 1TLCA 4E5OA 1F4CA 1NJCA 4ISKA 3CLBA 4EINA 1KZIA 4KY8A 4PSGA 4EZ8A 1HW3A 4DP3A 1F4BA 1J3KC 3BFIA 1TSDA 1KZJA 5HS3A 1RTSA 4IQQA 1BKPA 4IQBA 1BDUA 1VZDA 3BYXA 2AAZA 3BGXA 1EV8A 2TSRA 3TMSA 1LCAA 4G6WX 4FGTA 3EBUA 3KJSA 1BP6A 1HW4A 1AXWA 1TSYA 4LRRA 1TSNA 5H3AA 3HJ3A 1TDUA 4O1UA 1BSPA 2A9WA 4IRRA 4DPHA 2RD8B 3IJZA 4XSDA 4EILA 4H0RA 1JMGA 3HBBA 3UWLA 1BSFA 1THYA 1FFLA 1B02A 3EGYX 1JTQA 1JUJA 1VZBA 1FWMA 3K2HA 1TVWA 4FOAA 4KY4A 1TSZA 1AIQA 4UP1A 5FCTA 1NJDA 1TSWA 1BO7A 3KGBA 3QG2A 1J3IC 1TDBA 2G8AA 1YPVA 3IK0A 3KJRA 4ECKA 2TSCA 1EVFA 3C06A 1J3JC 1TSMA 3UM6A 3BNZA 1TSVA 1TYSA 1EV5A 3IK1A 3QJ7A 3N5GA 3EJLA 3DGAC 3B9HA 4F2VA 1B49A 2H2QA 3IX6A 1AN5A 2BBQA 1SEJA 1HZWA 3V8HA 4E28A 1JMFA 4O7UA 1BJGA 1DNAA 2RD8A 1ZPRA 4TMSA 1BQ2A 3JSUA 4XSCA 1TISA 4KPWA
chains in the Genus database with same CATH superfamily
4DPDA 2G8DA 3BZ0A 4G2OX 4DQ1A 4FOGA 3N5EB 1CI7A 4GD7A 2VF0A 3NRRA 4GYHA 5H38A 2G8XA 1NJBA 1LCBA 3UM8A 1HVYA 3UWLB 1DDUA 5BY6A 1SYNA 1BKOA 4H0UA 1LCEA 4JEFA 3INVA 2FTQA 3UM5A 1BPJA 1JTUA 1TDAA 3ED7A 1EVGA 1JMIA 1JMHA 3HB8A 1AOBA 3EF9A 3BHRA 2FTOX 1F4FA 2TDMA 4Q0DA 5H39A 1QZFA 1KCEA 4O1XA 1F4GA 4FQSA 3CL9A 3IHIA 1I00A 1TLSA 3DG8C 1F4EA 5WRNA 4EB4A 2VETA 2FTNA 3BHLA 3EAWX 2TDDA 1TDCA 4O1XD 3H9KA 1B5EA 1BQ1A 4GEVA 3I3RA 3EDWX 1AJMA 3GG5A 4ISWA 4KYAA 1NCEA 1VZEA 3OB7A 1VZAA 1TSLA 2KCEA 2G89A 1VZCA 2G86A 3IROA 2OIPA 3IRNA 4H1IA 1F28A 4KNZA 1QQQA 3B5BA 3QGTA 1TVVA 1JUTA 2RDAA 3IRMA 1TRGA 1BO8A 3GH2X 3N5EA 4XSEA 1BP0A 1BIDA 1NJEA 1TSXA 4Q0EA 4FOXA 1JU6A 3EHIX 1B5DA 1TVUA 3C0AA 3DL6A 2ONBA 1NJAA 1TJSA 1JG0A 1F4DA 5J7WA 3GH0A 3DL5A 1TLCA 4E5OA 1F4CA 1NJCA 4ISKA 3CLBA 4EINA 1KZIA 4KY8A 4PSGA 4EZ8A 1HW3A 4DP3A 1F4BA 1J3KC 3BFIA 1TSDA 1KZJA 5HS3A 1RTSA 4IQQA 1BKPA 4IQBA 1BDUA 1VZDA 3BYXA 2AAZA 3BGXA 1EV8A 2TSRA 3TMSA 1LCAA 4G6WX 4FGTA 3EBUA 3KJSA 1BP6A 1HW4A 1AXWA 1TSYA 4LRRA 1TSNA 5H3AA 3HJ3A 1TDUA 4O1UA 1BSPA 2A9WA 4IRRA 4DPHA 2RD8B 3IJZA 4XSDA 4EILA 4H0RA 1JMGA 3HBBA 3UWLA 1BSFA 1THYA 1FFLA 1B02A 3EGYX 1JTQA 1JUJA 1VZBA 1FWMA 3K2HA 1TVWA 4FOAA 4KY4A 1TSZA 1AIQA 4UP1A 5FCTA 1NJDA 1TSWA 1BO7A 3KGBA 3QG2A 1J3IC 1TDBA 2G8AA 1YPVA 3IK0A 3KJRA 4ECKA 2TSCA 1EVFA 3C06A 1J3JC 1TSMA 3UM6A 3BNZA 1TSVA 1TYSA 1EV5A 3IK1A 3QJ7A 3N5GA 3EJLA 3DGAC 3B9HA 4F2VA 1B49A 2H2QA 3IX6A 1AN5A 2BBQA 1SEJA 1HZWA 3V8HA 4E28A 1JMFA 4O7UA 1BJGA 1DNAA 2RD8A 1ZPRA 4TMSA 1BQ2A 3JSUA 4XSCA 1TISA 4KPWA
chains in the Genus database with same CATH topology
4DPDA 2G8DA 3BZ0A 4G2OX 4DQ1A 4FOGA 3N5EB 1CI7A 4GD7A 2VF0A 3NRRA 4GYHA 5H38A 2G8XA 1NJBA 1LCBA 3UM8A 1HVYA 3UWLB 1DDUA 5BY6A 1SYNA 1BKOA 4H0UA 1LCEA 4JEFA 3INVA 2FTQA 3UM5A 1BPJA 1JTUA 1TDAA 3ED7A 1EVGA 1JMIA 1JMHA 3HB8A 1AOBA 3EF9A 3BHRA 2FTOX 1F4FA 2TDMA 4Q0DA 5H39A 1QZFA 1KCEA 4O1XA 1F4GA 4FQSA 3CL9A 3IHIA 1I00A 1TLSA 3DG8C 1F4EA 5WRNA 4EB4A 2VETA 2FTNA 3BHLA 3EAWX 2TDDA 1TDCA 4O1XD 3H9KA 1B5EA 1BQ1A 4GEVA 3I3RA 3EDWX 1AJMA 3GG5A 4ISWA 4KYAA 1NCEA 1VZEA 3OB7A 1VZAA 1TSLA 2KCEA 2G89A 1VZCA 2G86A 3IROA 2OIPA 3IRNA 4H1IA 1F28A 4KNZA 1QQQA 3B5BA 3QGTA 1TVVA 1JUTA 2RDAA 3IRMA 1TRGA 1BO8A 3GH2X 3N5EA 4XSEA 1BP0A 1BIDA 1NJEA 1TSXA 4Q0EA 4FOXA 1JU6A 3EHIX 1B5DA 1TVUA 3C0AA 3DL6A 2ONBA 1NJAA 1TJSA 1JG0A 1F4DA 5J7WA 3GH0A 3DL5A 1TLCA 4E5OA 1F4CA 1NJCA 4ISKA 3CLBA 4EINA 1KZIA 4KY8A 4PSGA 4EZ8A 1HW3A 4DP3A 1F4BA 1J3KC 3BFIA 1TSDA 1KZJA 5HS3A 1RTSA 4IQQA 1BKPA 4IQBA 1BDUA 1VZDA 3BYXA 2AAZA 3BGXA 1EV8A 2TSRA 3TMSA 1LCAA 4G6WX 4FGTA 3EBUA 3KJSA 1BP6A 1HW4A 1AXWA 1TSYA 4LRRA 1TSNA 5H3AA 3HJ3A 1TDUA 4O1UA 1BSPA 2A9WA 4IRRA 4DPHA 2RD8B 3IJZA 4XSDA 4EILA 4H0RA 1JMGA 3HBBA 3UWLA 1BSFA 1THYA 1FFLA 1B02A 3EGYX 1JTQA 1JUJA 1VZBA 1FWMA 3K2HA 1TVWA 4FOAA 4KY4A 1TSZA 1AIQA 4UP1A 5FCTA 1NJDA 1TSWA 1BO7A 3KGBA 3QG2A 1J3IC 1TDBA 2G8AA 1YPVA 3IK0A 3KJRA 4ECKA 2TSCA 1EVFA 3C06A 1J3JC 1TSMA 3UM6A 3BNZA 1TSVA 1TYSA 1EV5A 3IK1A 3QJ7A 3N5GA 3EJLA 3DGAC 3B9HA 4F2VA 1B49A 2H2QA 3IX6A 1AN5A 2BBQA 1SEJA 1HZWA 3V8HA 4E28A 1JMFA 4O7UA 1BJGA 1DNAA 2RD8A 1ZPRA 4TMSA 1BQ2A 3JSUA 4XSCA 1TISA 4KPWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DPD A;  2G8D A;  3BZ0 A;  4G2O X;  4DQ1 A;  4FOG A;  3N5E B;  1CI7 A;  4GD7 A;  2VF0 A;  3NRR A;  4GYH A;  5H38 A;  2G8X A;  1NJB A;  1LCB A;  3UM8 A;  1HVY A;  3UWL B;  1DDU A;  5BY6 A;  1SYN A;  1BKO A;  4H0U A;  1LCE A;  4JEF A;  3INV A;  2FTQ A;  3UM5 A;  1BPJ A;  1JTU A;  1TDA A;  3ED7 A;  1EVG A;  1JMI A;  1JMH A;  3HB8 A;  1AOB A;  3EF9 A;  3BHR A;  2FTO X;  1F4F A;  2TDM A;  4Q0D A;  5H39 A;  1QZF A;  1KCE A;  4O1X A;  1F4G A;  4FQS A;  3CL9 A;  3IHI A;  1I00 A;  1TLS A;  3DG8 C;  1F4E A;  5WRN A;  4EB4 A;  2VET A;  2FTN A;  3BHL A;  3EAW X;  2TDD A;  1TDC A;  4O1X D;  3H9K A;  1B5E A;  1BQ1 A;  4GEV A;  3I3R A;  3EDW X;  1AJM A;  3GG5 A;  4ISW A;  4KYA A;  1NCE A;  1VZE A;  3OB7 A;  1VZA A;  1TSL A;  2KCE A;  2G89 A;  1VZC A;  2G86 A;  3IRO A;  2OIP A;  3IRN A;  4H1I A;  1F28 A;  4KNZ A;  1QQQ A;  3B5B A;  3QGT A;  1TVV A;  1JUT A;  2RDA A;  3IRM A;  1TRG A;  1BO8 A;  3GH2 X;  3N5E A;  4XSE A;  1BP0 A;  1BID A;  1NJE A;  1TSX A;  4Q0E A;  4FOX A;  1JU6 A;  3EHI X;  1B5D A;  1TVU A;  3C0A A;  3DL6 A;  2ONB A;  1NJA A;  1TJS A;  1JG0 A;  1F4D A;  5J7W A;  3GH0 A;  3DL5 A;  1TLC A;  4E5O A;  1F4C A;  1NJC A;  4ISK A;  3CLB A;  4EIN A;  1KZI A;  4KY8 A;  4PSG A;  4EZ8 A;  1HW3 A;  4DP3 A;  1F4B A;  1J3K C;  3BFI A;  1TSD A;  1KZJ A;  5HS3 A;  1RTS A;  4IQQ A;  1BKP A;  4IQB A;  1BDU A;  1VZD A;  3BYX A;  2AAZ A;  3BGX A;  1EV8 A;  2TSR A;  3TMS A;  1LCA A;  4G6W X;  4FGT A;  3EBU A;  3KJS A;  1BP6 A;  1HW4 A;  1AXW A;  1TSY A;  4LRR A;  1TSN A;  5H3A A;  3HJ3 A;  1TDU A;  4O1U A;  1BSP A;  2A9W A;  4IRR A;  4DPH A;  2RD8 B;  3IJZ A;  4XSD A;  4EIL A;  4H0R A;  1JMG A;  3HBB A;  3UWL A;  1BSF A;  1THY A;  1FFL A;  1B02 A;  3EGY X;  1JTQ A;  1JUJ A;  1VZB A;  1FWM A;  3K2H A;  1TVW A;  4FOA A;  4KY4 A;  1TSZ A;  1AIQ A;  4UP1 A;  5FCT A;  1NJD A;  1TSW A;  1BO7 A;  3KGB A;  3QG2 A;  1J3I C;  1TDB A;  2G8A A;  1YPV A;  3IK0 A;  3KJR A;  4ECK A;  2TSC A;  1EVF A;  3C06 A;  1J3J C;  1TSM A;  3UM6 A;  3BNZ A;  1TSV A;  1TYS A;  1EV5 A;  3IK1 A;  3QJ7 A;  3N5G A;  3EJL A;  3DGA C;  3B9H A;  4F2V A;  1B49 A;  2H2Q A;  3IX6 A;  1AN5 A;  2BBQ A;  1SEJ A;  1HZW A;  3V8H A;  4E28 A;  1JMF A;  4O7U A;  1BJG A;  1DNA A;  2RD8 A;  1ZPR A;  4TMS A;  1BQ2 A;  3JSU A;  4XSC A;  1TIS A;  4KPW A; 
#chains in the Genus database with same CATH topology
 4DPD A;  2G8D A;  3BZ0 A;  4G2O X;  4DQ1 A;  4FOG A;  3N5E B;  1CI7 A;  4GD7 A;  2VF0 A;  3NRR A;  4GYH A;  5H38 A;  2G8X A;  1NJB A;  1LCB A;  3UM8 A;  1HVY A;  3UWL B;  1DDU A;  5BY6 A;  1SYN A;  1BKO A;  4H0U A;  1LCE A;  4JEF A;  3INV A;  2FTQ A;  3UM5 A;  1BPJ A;  1JTU A;  1TDA A;  3ED7 A;  1EVG A;  1JMI A;  1JMH A;  3HB8 A;  1AOB A;  3EF9 A;  3BHR A;  2FTO X;  1F4F A;  2TDM A;  4Q0D A;  5H39 A;  1QZF A;  1KCE A;  4O1X A;  1F4G A;  4FQS A;  3CL9 A;  3IHI A;  1I00 A;  1TLS A;  3DG8 C;  1F4E A;  5WRN A;  4EB4 A;  2VET A;  2FTN A;  3BHL A;  3EAW X;  2TDD A;  1TDC A;  4O1X D;  3H9K A;  1B5E A;  1BQ1 A;  4GEV A;  3I3R A;  3EDW X;  1AJM A;  3GG5 A;  4ISW A;  4KYA A;  1NCE A;  1VZE A;  3OB7 A;  1VZA A;  1TSL A;  2KCE A;  2G89 A;  1VZC A;  2G86 A;  3IRO A;  2OIP A;  3IRN A;  4H1I A;  1F28 A;  4KNZ A;  1QQQ A;  3B5B A;  3QGT A;  1TVV A;  1JUT A;  2RDA A;  3IRM A;  1TRG A;  1BO8 A;  3GH2 X;  3N5E A;  4XSE A;  1BP0 A;  1BID A;  1NJE A;  1TSX A;  4Q0E A;  4FOX A;  1JU6 A;  3EHI X;  1B5D A;  1TVU A;  3C0A A;  3DL6 A;  2ONB A;  1NJA A;  1TJS A;  1JG0 A;  1F4D A;  5J7W A;  3GH0 A;  3DL5 A;  1TLC A;  4E5O A;  1F4C A;  1NJC A;  4ISK A;  3CLB A;  4EIN A;  1KZI A;  4KY8 A;  4PSG A;  4EZ8 A;  1HW3 A;  4DP3 A;  1F4B A;  1J3K C;  3BFI A;  1TSD A;  1KZJ A;  5HS3 A;  1RTS A;  4IQQ A;  1BKP A;  4IQB A;  1BDU A;  1VZD A;  3BYX A;  2AAZ A;  3BGX A;  1EV8 A;  2TSR A;  3TMS A;  1LCA A;  4G6W X;  4FGT A;  3EBU A;  3KJS A;  1BP6 A;  1HW4 A;  1AXW A;  1TSY A;  4LRR A;  1TSN A;  5H3A A;  3HJ3 A;  1TDU A;  4O1U A;  1BSP A;  2A9W A;  4IRR A;  4DPH A;  2RD8 B;  3IJZ A;  4XSD A;  4EIL A;  4H0R A;  1JMG A;  3HBB A;  3UWL A;  1BSF A;  1THY A;  1FFL A;  1B02 A;  3EGY X;  1JTQ A;  1JUJ A;  1VZB A;  1FWM A;  3K2H A;  1TVW A;  4FOA A;  4KY4 A;  1TSZ A;  1AIQ A;  4UP1 A;  5FCT A;  1NJD A;  1TSW A;  1BO7 A;  3KGB A;  3QG2 A;  1J3I C;  1TDB A;  2G8A A;  1YPV A;  3IK0 A;  3KJR A;  4ECK A;  2TSC A;  1EVF A;  3C06 A;  1J3J C;  1TSM A;  3UM6 A;  3BNZ A;  1TSV A;  1TYS A;  1EV5 A;  3IK1 A;  3QJ7 A;  3N5G A;  3EJL A;  3DGA C;  3B9H A;  4F2V A;  1B49 A;  2H2Q A;  3IX6 A;  1AN5 A;  2BBQ A;  1SEJ A;  1HZW A;  3V8H A;  4E28 A;  1JMF A;  4O7U A;  1BJG A;  1DNA A;  2RD8 A;  1ZPR A;  4TMS A;  1BQ2 A;  3JSU A;  4XSC A;  1TIS A;  4KPW A; 
#chains in the Genus database with same CATH homology
 4DPD A;  2G8D A;  3BZ0 A;  4G2O X;  4DQ1 A;  4FOG A;  3N5E B;  1CI7 A;  4GD7 A;  2VF0 A;  3NRR A;  4GYH A;  5H38 A;  2G8X A;  1NJB A;  1LCB A;  3UM8 A;  1HVY A;  3UWL B;  1DDU A;  5BY6 A;  1SYN A;  1BKO A;  4H0U A;  1LCE A;  4JEF A;  3INV A;  2FTQ A;  3UM5 A;  1BPJ A;  1JTU A;  1TDA A;  3ED7 A;  1EVG A;  1JMI A;  1JMH A;  3HB8 A;  1AOB A;  3EF9 A;  3BHR A;  2FTO X;  1F4F A;  2TDM A;  4Q0D A;  5H39 A;  1QZF A;  1KCE A;  4O1X A;  1F4G A;  4FQS A;  3CL9 A;  3IHI A;  1I00 A;  1TLS A;  3DG8 C;  1F4E A;  5WRN A;  4EB4 A;  2VET A;  2FTN A;  3BHL A;  3EAW X;  2TDD A;  1TDC A;  4O1X D;  3H9K A;  1B5E A;  1BQ1 A;  4GEV A;  3I3R A;  3EDW X;  1AJM A;  3GG5 A;  4ISW A;  4KYA A;  1NCE A;  1VZE A;  3OB7 A;  1VZA A;  1TSL A;  2KCE A;  2G89 A;  1VZC A;  2G86 A;  3IRO A;  2OIP A;  3IRN A;  4H1I A;  1F28 A;  4KNZ A;  1QQQ A;  3B5B A;  3QGT A;  1TVV A;  1JUT A;  2RDA A;  3IRM A;  1TRG A;  1BO8 A;  3GH2 X;  3N5E A;  4XSE A;  1BP0 A;  1BID A;  1NJE A;  1TSX A;  4Q0E A;  4FOX A;  1JU6 A;  3EHI X;  1B5D A;  1TVU A;  3C0A A;  3DL6 A;  2ONB A;  1NJA A;  1TJS A;  1JG0 A;  1F4D A;  5J7W A;  3GH0 A;  3DL5 A;  1TLC A;  4E5O A;  1F4C A;  1NJC A;  4ISK A;  3CLB A;  4EIN A;  1KZI A;  4KY8 A;  4PSG A;  4EZ8 A;  1HW3 A;  4DP3 A;  1F4B A;  1J3K C;  3BFI A;  1TSD A;  1KZJ A;  5HS3 A;  1RTS A;  4IQQ A;  1BKP A;  4IQB A;  1BDU A;  1VZD A;  3BYX A;  2AAZ A;  3BGX A;  1EV8 A;  2TSR A;  3TMS A;  1LCA A;  4G6W X;  4FGT A;  3EBU A;  3KJS A;  1BP6 A;  1HW4 A;  1AXW A;  1TSY A;  4LRR A;  1TSN A;  5H3A A;  3HJ3 A;  1TDU A;  4O1U A;  1BSP A;  2A9W A;  4IRR A;  4DPH A;  2RD8 B;  3IJZ A;  4XSD A;  4EIL A;  4H0R A;  1JMG A;  3HBB A;  3UWL A;  1BSF A;  1THY A;  1FFL A;  1B02 A;  3EGY X;  1JTQ A;  1JUJ A;  1VZB A;  1FWM A;  3K2H A;  1TVW A;  4FOA A;  4KY4 A;  1TSZ A;  1AIQ A;  4UP1 A;  5FCT A;  1NJD A;  1TSW A;  1BO7 A;  3KGB A;  3QG2 A;  1J3I C;  1TDB A;  2G8A A;  1YPV A;  3IK0 A;  3KJR A;  4ECK A;  2TSC A;  1EVF A;  3C06 A;  1J3J C;  1TSM A;  3UM6 A;  3BNZ A;  1TSV A;  1TYS A;  1EV5 A;  3IK1 A;  3QJ7 A;  3N5G A;  3EJL A;  3DGA C;  3B9H A;  4F2V A;  1B49 A;  2H2Q A;  3IX6 A;  1AN5 A;  2BBQ A;  1SEJ A;  1HZW A;  3V8H A;  4E28 A;  1JMF A;  4O7U A;  1BJG A;  1DNA A;  2RD8 A;  1ZPR A;  4TMS A;  1BQ2 A;  3JSU A;  4XSC A;  1TIS A;  4KPW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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