1AOEA

Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 1,3-diamino-7-(1-ethyepropye)-7h-pyrralo-[3,2-f]quinazoline (gw345)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
192
structure length
192
Chain Sequence
MLKPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase
source organism Candida albicans
total genus 56
structure length 192
sequence length 192
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1997-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1aoeA00
3M09A 3M08A 3CLBA 1LY3A 1DG8A 1DRHA 1DHFA 3QGTA 3NXTA 4Q6AA 4HA9A 3F8YA 2LF1A 3NZ6X 4EIZA 3TQ9A 2XW7A 3JWFA 2HXVA 3EEKA 3EELA 4PSTA 4ELEA 1S3UA 2C2TA 3FQFA 4M6KA 5ECXA 4QJCA 3QFXA 2G6VA 3NXOA 3FRFX 1RA8A 4I13A 5HF2X 1DYHA 3IA5A 1DYIA 3K47A 4X5HA 1DISA 3FQCA 4XRBA 2CIGA 3Q1HA 2W3VA 1PD8A 3SQYX 3F0VX 3IA4A 4Q0DA 4LEKX 3QLRA 1CZ3A 5HF0X 3RO9A 3JWKA 1M7AA 3I3RA 4G95A 3IROA 4QJZD 1RB3A 1RB2A 2ANOA 3QLSA 4XT4A 1DHIA 1DR1A 5HQZA 1DYRA 4KEBA 3SRSX 4M6JA 3QLYA 2W9HA 3OAFA 4ELGA 4G3MA 3QLZA 2W3AA 5FDAA 2BLBA 4QI9A 3SH2A 3F0QX 8DFRA 4KJKA 1VJ3A 1OHJA 1RA2A 3CL9A 3NRRA 1RX6A 4ELBA 4ECKA 3UM5A 1AOEA 5HT4A 3EEMA 4KD7A 3RG9A 3QL3A 1IA4A 1DDRA 2CD2A 1E26A 3GYFA 5HSUA 1IA3A 3NZCX 2W3BA 3VCOA 1JUVA 3I8AX 4QLGA 3KY8A 2JYBA 3K2HA 5JA3A 3FL8A 3FQVA 3NXRA 3SRWX 3CD2A 1LUDA 3FREX 1DR6A 1RA3A 2KGKA 1RF7A 2D5NA 3NZAX 4KY8A 5E8QA 4HOGA 4PDJA 1DHJA 3OCHA 3K45A 4HA7A 4KLXA 3SAIA 4DFRA 4LAEX 5HT5A 3DL6A 3SGYA 1VDRA 3SA1A 5HPBA 1DREA 1IA1A 3F91A 1PD9A 3D80A 1KLKA 2W3WA 4Q0EA 4QLFA 2QK8A 2HM9A 3DG8A 3DRCA 4DP3A 3NXXA 4KY4A 1RA1A 5DFRA 5DXVA 3S9UA 3FL9A 1J3IA 4FHBA 4KM2A 4KYAA 3DGAA 6DFRA 4KL9A 3SA2A 1DR5A 3FY8X 3L3RA 4XT8A 1DRFA 4NX7A 4P3QA 3F0UX 3ZPCA 4FGGA 3KGYA 1LY4A 4EILA 1M79A 2OBCA 1RH3A 1S3YA 4XT7A 2B3ZA 1JOLA 1TDRA 1U72A 3FRAX 2H2QA 1RE7A 5HI6A 5U27A 3JW5A 7DFRA 5CCCA 4M7VA 3QYLA 2INQA 4M6LA 3GI2A 1DG7A 4HOEA 3JWCA 1U70A 4P68A 1KMSA 1RX8A 1DR4A 1U71A 1S3VA 3CSEA 2HQPA 4KAKA 4X5IA 3JTWA 1BOZA 1M78A 2BLCA 4H96A 2ZZAA 4EJ1A 1KMVA 2DRCA 3ZPGA 3GHWA 1DR3A 1D1GA 4XT6A 1OHKA 3N0HA 3UM8A 3TQ8A 1YHOA 1HFPA 4X5JA 3DATA 4XT5A 3NXYA 1ZDRA 3TQAA 4H95A 3QLXA 3DFRA 1RX4A 4LAHX 3FYVX 4EIGA 4P3RA 4QHVA 5JG0X 1PDBA 3KJSA 3JWMA 1HFRA 3S7AA 4FGHA 3NZ9X 3FY9X 4PTJA 4ELHA 1QZFA 3F8ZA 1DRAA 2FZIA 1RX5A 4PSYA 2ANQA 3TQBA 1DF7A 4XE6X 1SEJA 4KM0A 4M7UA 4DPHA 3F0XX 4KBNA 3LG4A 4GH8A 2W9GA 3QYOA 3SRUX 4CD2A 1DR7A 3E0BA 3FQZA 4HOFA 3FRBX 5U26A 3INVA 4OR7A 4DDRA 3QL0A 1J3JA 3HBBA 1MVSA 1AO8A 2L28A 1AI9A 4G8ZX 3F0SX 2W9SA 3D84X 3EEJA 3SRRX 5HUIA 1RX9A 1IA2A 3SRQX 1J3KA 3NZDA 3GHCA 3K74A 3QG2A 2AZNA 3FRDX 4H98A 2P4GA 4IXFX 1JOMA 3NU0A 3NTZA 3EIGA 1DLSA 1DRBA 4I1NA 5HQYA 4IXED 1RX2A 3TD8A 4IXGX 3S3VA 2FZHA 2DHFA 3FQOA 2OIPA 4KJLA 4P66A 2O7PA 1DAJA 3JSUA 1MVTA 3IRNA 4OSGA 4H97A 2C2SA 4XECX 4RGCA 3IRMA 1RC4A 3EX8A 1DLRA 3FS6A 3DL5A 3F0BX 4M2XA 4Q67A 1HFQA 3R33A 5EAJA 2BLAA 2GD9A 2ITHA 2W9TA 4PSSA 3JVXA 3KJRA 2W3MA 4X5FA 3ROAA 2BL9A 3KFYA 3FYWX 1RX7A 1RX1A 3UM6A 5HSRA 4LAGX 3DAUA 4X5GA 1CD2A 1DYJA 5ECCA 1BZFA 2FZJA 1DR2A 3NZBX 1RG7A 3QLWA 5HVEA 3HJ3A 4PTHA 3FQ0A 4KJJA 5CC9A 1RX3A 1DIUA 1RA9A 3SR5X 3NXVA 1DG5A 4DPDA 4TU5X 2D0KA 5HVBA 1S3WA 4NX6A 4ELFA 1DDSA 3JW3A 1RD7A 4KFJA 4QLEA 3IX9A 4KNEA 3GHVA
chains in the Genus database with same CATH superfamily
3M09A 3M08A 3CLBA 1LY3A 1DG8A 1DRHA 1DHFA 3QGTA 3NXTA 4Q6AA 4HA9A 3F8YA 2LF1A 3NZ6X 4EIZA 3TQ9A 2XW7A 3JWFA 2HXVA 3EEKA 3EELA 4PSTA 4ELEA 1S3UA 2C2TA 3FQFA 4M6KA 5ECXA 4QJCA 3QFXA 2G6VA 3NXOA 3FRFX 1RA8A 4I13A 5HF2X 1DYHA 3IA5A 1DYIA 3K47A 4X5HA 1DISA 3FQCA 4XRBA 2CIGA 3Q1HA 2W3VA 1PD8A 3SQYX 3F0VX 3IA4A 4Q0DA 4LEKX 3QLRA 1CZ3A 5HF0X 3RO9A 3JWKA 1M7AA 3I3RA 4G95A 3IROA 4QJZD 1RB3A 1RB2A 2ANOA 3QLSA 4XT4A 1DHIA 1DR1A 5HQZA 1DYRA 4KEBA 3SRSX 4M6JA 3QLYA 2W9HA 3OAFA 4ELGA 4G3MA 3QLZA 2W3AA 5FDAA 2BLBA 4QI9A 3SH2A 3F0QX 8DFRA 4KJKA 1VJ3A 1OHJA 1RA2A 3CL9A 3NRRA 1RX6A 4ELBA 4ECKA 3UM5A 1AOEA 5HT4A 3EEMA 4KD7A 3RG9A 3QL3A 1IA4A 1DDRA 2CD2A 1E26A 3GYFA 5HSUA 1IA3A 3NZCX 2W3BA 3VCOA 1JUVA 3I8AX 4QLGA 3KY8A 2JYBA 3K2HA 5JA3A 3FL8A 3FQVA 3NXRA 3SRWX 3CD2A 1LUDA 3FREX 1DR6A 1RA3A 2KGKA 1RF7A 2D5NA 3NZAX 4KY8A 5E8QA 4HOGA 4PDJA 1DHJA 3OCHA 3K45A 4HA7A 4KLXA 3SAIA 4DFRA 4LAEX 5HT5A 3DL6A 3SGYA 1VDRA 3SA1A 5HPBA 1DREA 1IA1A 3F91A 1PD9A 3D80A 1KLKA 2W3WA 4Q0EA 4QLFA 2QK8A 2HM9A 3DG8A 3DRCA 4DP3A 3NXXA 4KY4A 1RA1A 5DFRA 5DXVA 3S9UA 3FL9A 1J3IA 4FHBA 4KM2A 4KYAA 3DGAA 6DFRA 4KL9A 3SA2A 1DR5A 3FY8X 3L3RA 4XT8A 1DRFA 4NX7A 4P3QA 3F0UX 3ZPCA 4FGGA 3KGYA 1LY4A 4EILA 1M79A 2OBCA 1RH3A 1S3YA 4XT7A 2B3ZA 1JOLA 1TDRA 1U72A 3FRAX 2H2QA 1RE7A 5HI6A 5U27A 3JW5A 7DFRA 5CCCA 4M7VA 3QYLA 2INQA 4M6LA 3GI2A 1DG7A 4HOEA 3JWCA 1U70A 4P68A 1KMSA 1RX8A 1DR4A 1U71A 1S3VA 3CSEA 2HQPA 4KAKA 4X5IA 3JTWA 1BOZA 1M78A 2BLCA 4H96A 2ZZAA 4EJ1A 1KMVA 2DRCA 3ZPGA 3GHWA 1DR3A 1D1GA 4XT6A 1OHKA 3N0HA 3UM8A 3TQ8A 1YHOA 1HFPA 4X5JA 3DATA 4XT5A 3NXYA 1ZDRA 3TQAA 4H95A 3QLXA 3DFRA 1RX4A 4LAHX 3FYVX 4EIGA 4P3RA 4QHVA 5JG0X 1PDBA 3KJSA 3JWMA 1HFRA 3S7AA 4FGHA 3NZ9X 3FY9X 4PTJA 4ELHA 1QZFA 3F8ZA 1DRAA 2FZIA 1RX5A 4PSYA 2ANQA 3TQBA 1DF7A 4XE6X 1SEJA 4KM0A 4M7UA 4DPHA 3F0XX 4KBNA 3LG4A 4GH8A 2W9GA 3QYOA 3SRUX 4CD2A 1DR7A 3E0BA 3FQZA 4HOFA 3FRBX 5U26A 3INVA 4OR7A 4DDRA 3QL0A 1J3JA 3HBBA 1MVSA 1AO8A 2L28A 1AI9A 4G8ZX 3F0SX 2W9SA 3D84X 3EEJA 3SRRX 5HUIA 1RX9A 1IA2A 3SRQX 1J3KA 3NZDA 3GHCA 3K74A 3QG2A 2AZNA 3FRDX 4H98A 2P4GA 4IXFX 1JOMA 3NU0A 3NTZA 3EIGA 1DLSA 1DRBA 4I1NA 5HQYA 4IXED 1RX2A 3TD8A 4IXGX 3S3VA 2FZHA 2DHFA 3FQOA 2OIPA 4KJLA 4P66A 2O7PA 1DAJA 3JSUA 1MVTA 3IRNA 4OSGA 4H97A 2C2SA 4XECX 4RGCA 3IRMA 1RC4A 3EX8A 1DLRA 3FS6A 3DL5A 3F0BX 4M2XA 4Q67A 1HFQA 3R33A 5EAJA 2BLAA 2GD9A 2ITHA 2W9TA 4PSSA 3JVXA 3KJRA 2W3MA 4X5FA 3ROAA 2BL9A 3KFYA 3FYWX 1RX7A 1RX1A 3UM6A 5HSRA 4LAGX 3DAUA 4X5GA 1CD2A 1DYJA 5ECCA 1BZFA 2FZJA 1DR2A 3NZBX 1RG7A 3QLWA 5HVEA 3HJ3A 4PTHA 3FQ0A 4KJJA 5CC9A 1RX3A 1DIUA 1RA9A 3SR5X 3NXVA 1DG5A 4DPDA 4TU5X 2D0KA 5HVBA 1S3WA 4NX6A 4ELFA 1DDSA 3JW3A 1RD7A 4KFJA 4QLEA 3IX9A 4KNEA 3GHVA
chains in the Genus database with same CATH topology
3M09A 3M08A 3CLBA 1LY3A 1DG8A 1DRHA 1DHFA 3QGTA 3NXTA 4Q6AA 4HA9A 3F8YA 2LF1A 3NZ6X 4EIZA 3TQ9A 2XW7A 3JWFA 2HXVA 3EEKA 3EELA 4PSTA 4ELEA 1S3UA 2C2TA 3FQFA 4M6KA 5ECXA 4QJCA 3QFXA 2G6VA 3NXOA 3FRFX 1RA8A 4I13A 5HF2X 1DYHA 3IA5A 1DYIA 3K47A 4X5HA 1DISA 3FQCA 4XRBA 2CIGA 3Q1HA 2W3VA 1PD8A 3SQYX 3F0VX 3IA4A 4Q0DA 4LEKX 3QLRA 1CZ3A 5HF0X 3RO9A 3JWKA 1M7AA 3I3RA 4G95A 3IROA 4QJZD 1RB3A 1RB2A 2ANOA 3QLSA 4XT4A 1DHIA 1DR1A 5HQZA 1DYRA 4KEBA 3SRSX 4M6JA 3QLYA 2W9HA 3OAFA 4ELGA 4G3MA 3QLZA 2W3AA 5FDAA 2BLBA 4QI9A 3SH2A 3F0QX 8DFRA 4KJKA 1VJ3A 1OHJA 1RA2A 3CL9A 3NRRA 1RX6A 4ELBA 4ECKA 3UM5A 1AOEA 5HT4A 3EEMA 4KD7A 3RG9A 3QL3A 1IA4A 1DDRA 2CD2A 1E26A 3GYFA 5HSUA 1IA3A 3NZCX 2W3BA 3VCOA 1JUVA 3I8AX 4QLGA 3KY8A 2JYBA 3K2HA 5JA3A 3FL8A 3FQVA 3NXRA 3SRWX 3CD2A 1LUDA 3FREX 1DR6A 1RA3A 2KGKA 1RF7A 2D5NA 3NZAX 4KY8A 5E8QA 4HOGA 4PDJA 1DHJA 3OCHA 3K45A 4HA7A 4KLXA 3SAIA 4DFRA 4LAEX 5HT5A 3DL6A 3SGYA 1VDRA 3SA1A 5HPBA 1DREA 1IA1A 3F91A 1PD9A 3D80A 1KLKA 2W3WA 4Q0EA 4QLFA 2QK8A 2HM9A 3DG8A 3DRCA 4DP3A 3NXXA 4KY4A 1RA1A 5DFRA 5DXVA 3S9UA 3FL9A 1J3IA 4FHBA 4KM2A 4KYAA 3DGAA 6DFRA 4KL9A 3SA2A 1DR5A 3FY8X 3L3RA 4XT8A 1DRFA 4NX7A 4P3QA 3F0UX 3ZPCA 4FGGA 3KGYA 1LY4A 4EILA 1M79A 2OBCA 1RH3A 1S3YA 4XT7A 2B3ZA 1JOLA 1TDRA 1U72A 3FRAX 2H2QA 1RE7A 5HI6A 5U27A 3JW5A 7DFRA 5CCCA 4M7VA 3QYLA 2INQA 4M6LA 3GI2A 1DG7A 4HOEA 3JWCA 1U70A 4P68A 1KMSA 1RX8A 1DR4A 1U71A 1S3VA 3CSEA 2HQPA 4KAKA 4X5IA 3JTWA 1BOZA 1M78A 2BLCA 4H96A 2ZZAA 4EJ1A 1KMVA 2DRCA 3ZPGA 3GHWA 1DR3A 1D1GA 4XT6A 1OHKA 3N0HA 3UM8A 3TQ8A 1YHOA 1HFPA 4X5JA 3DATA 4XT5A 3NXYA 1ZDRA 3TQAA 4H95A 3QLXA 3DFRA 1RX4A 4LAHX 3FYVX 4EIGA 4P3RA 4QHVA 5JG0X 1PDBA 3KJSA 3JWMA 1HFRA 3S7AA 4FGHA 3NZ9X 3FY9X 4PTJA 4ELHA 1QZFA 3F8ZA 1DRAA 2FZIA 1RX5A 4PSYA 2ANQA 3TQBA 1DF7A 4XE6X 1SEJA 4KM0A 4M7UA 4DPHA 3F0XX 4KBNA 3LG4A 4GH8A 2W9GA 3QYOA 3SRUX 4CD2A 1DR7A 3E0BA 3FQZA 4HOFA 3FRBX 5U26A 3INVA 4OR7A 4DDRA 3QL0A 1J3JA 3HBBA 1MVSA 1AO8A 2L28A 1AI9A 4G8ZX 3F0SX 2W9SA 3D84X 3EEJA 3SRRX 5HUIA 1RX9A 1IA2A 3SRQX 1J3KA 3NZDA 3GHCA 3K74A 3QG2A 2AZNA 3FRDX 4H98A 2P4GA 4IXFX 1JOMA 3NU0A 3NTZA 3EIGA 1DLSA 1DRBA 4I1NA 5HQYA 4IXED 1RX2A 3TD8A 4IXGX 3S3VA 2FZHA 2DHFA 3FQOA 2OIPA 4KJLA 4P66A 2O7PA 1DAJA 3JSUA 1MVTA 3IRNA 4OSGA 4H97A 2C2SA 4XECX 4RGCA 3IRMA 1RC4A 3EX8A 1DLRA 3FS6A 3DL5A 3F0BX 4M2XA 4Q67A 1HFQA 3R33A 5EAJA 2BLAA 2GD9A 2ITHA 2W9TA 4PSSA 3JVXA 3KJRA 2W3MA 4X5FA 3ROAA 2BL9A 3KFYA 3FYWX 1RX7A 1RX1A 3UM6A 5HSRA 4LAGX 3DAUA 4X5GA 1CD2A 1DYJA 5ECCA 1BZFA 2FZJA 1DR2A 3NZBX 1RG7A 3QLWA 5HVEA 3HJ3A 4PTHA 3FQ0A 4KJJA 5CC9A 1RX3A 1DIUA 1RA9A 3SR5X 3NXVA 1DG5A 4DPDA 4TU5X 2D0KA 5HVBA 1S3WA 4NX6A 4ELFA 1DDSA 3JW3A 1RD7A 4KFJA 4QLEA 3IX9A 4KNEA 3GHVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M09 A;  3M08 A;  3CLB A;  1LY3 A;  1DG8 A;  1DRH A;  1DHF A;  3QGT A;  3NXT A;  4Q6A A;  4HA9 A;  3F8Y A;  2LF1 A;  3NZ6 X;  4EIZ A;  3TQ9 A;  2XW7 A;  3JWF A;  2HXV A;  3EEK A;  3EEL A;  4PST A;  4ELE A;  1S3U A;  2C2T A;  3FQF A;  4M6K A;  5ECX A;  4QJC A;  3QFX A;  2G6V A;  3NXO A;  3FRF X;  1RA8 A;  4I13 A;  5HF2 X;  1DYH A;  3IA5 A;  1DYI A;  3K47 A;  4X5H A;  1DIS A;  3FQC A;  4XRB A;  2CIG A;  3Q1H A;  2W3V A;  1PD8 A;  3SQY X;  3F0V X;  3IA4 A;  4Q0D A;  4LEK X;  3QLR A;  1CZ3 A;  5HF0 X;  3RO9 A;  3JWK A;  1M7A A;  3I3R A;  4G95 A;  3IRO A;  4QJZ D;  1RB3 A;  1RB2 A;  2ANO A;  3QLS A;  4XT4 A;  1DHI A;  1DR1 A;  5HQZ A;  1DYR A;  4KEB A;  3SRS X;  4M6J A;  3QLY A;  2W9H A;  3OAF A;  4ELG A;  4G3M A;  3QLZ A;  2W3A A;  5FDA A;  2BLB A;  4QI9 A;  3SH2 A;  3F0Q X;  8DFR A;  4KJK A;  1VJ3 A;  1OHJ A;  1RA2 A;  3CL9 A;  3NRR A;  1RX6 A;  4ELB A;  4ECK A;  3UM5 A;  1AOE A;  5HT4 A;  3EEM A;  4KD7 A;  3RG9 A;  3QL3 A;  1IA4 A;  1DDR A;  2CD2 A;  1E26 A;  3GYF A;  5HSU A;  1IA3 A;  3NZC X;  2W3B A;  3VCO A;  1JUV A;  3I8A X;  4QLG A;  3KY8 A;  2JYB A;  3K2H A;  5JA3 A;  3FL8 A;  3FQV A;  3NXR A;  3SRW X;  3CD2 A;  1LUD A;  3FRE X;  1DR6 A;  1RA3 A;  2KGK A;  1RF7 A;  2D5N A;  3NZA X;  4KY8 A;  5E8Q A;  4HOG A;  4PDJ A;  1DHJ A;  3OCH A;  3K45 A;  4HA7 A;  4KLX A;  3SAI A;  4DFR A;  4LAE X;  5HT5 A;  3DL6 A;  3SGY A;  1VDR A;  3SA1 A;  5HPB A;  1DRE A;  1IA1 A;  3F91 A;  1PD9 A;  3D80 A;  1KLK A;  2W3W A;  4Q0E A;  4QLF A;  2QK8 A;  2HM9 A;  3DG8 A;  3DRC A;  4DP3 A;  3NXX A;  4KY4 A;  1RA1 A;  5DFR A;  5DXV A;  3S9U A;  3FL9 A;  1J3I A;  4FHB A;  4KM2 A;  4KYA A;  3DGA A;  6DFR A;  4KL9 A;  3SA2 A;  1DR5 A;  3FY8 X;  3L3R A;  4XT8 A;  1DRF A;  4NX7 A;  4P3Q A;  3F0U X;  3ZPC A;  4FGG A;  3KGY A;  1LY4 A;  4EIL A;  1M79 A;  2OBC A;  1RH3 A;  1S3Y A;  4XT7 A;  2B3Z A;  1JOL A;  1TDR A;  1U72 A;  3FRA X;  2H2Q A;  1RE7 A;  5HI6 A;  5U27 A;  3JW5 A;  7DFR A;  5CCC A;  4M7V A;  3QYL A;  2INQ A;  4M6L A;  3GI2 A;  1DG7 A;  4HOE A;  3JWC A;  1U70 A;  4P68 A;  1KMS A;  1RX8 A;  1DR4 A;  1U71 A;  1S3V A;  3CSE A;  2HQP A;  4KAK A;  4X5I A;  3JTW A;  1BOZ A;  1M78 A;  2BLC A;  4H96 A;  2ZZA A;  4EJ1 A;  1KMV A;  2DRC A;  3ZPG A;  3GHW A;  1DR3 A;  1D1G A;  4XT6 A;  1OHK A;  3N0H A;  3UM8 A;  3TQ8 A;  1YHO A;  1HFP A;  4X5J A;  3DAT A;  4XT5 A;  3NXY A;  1ZDR A;  3TQA A;  4H95 A;  3QLX A;  3DFR A;  1RX4 A;  4LAH X;  3FYV X;  4EIG A;  4P3R A;  4QHV A;  5JG0 X;  1PDB A;  3KJS A;  3JWM A;  1HFR A;  3S7A A;  4FGH A;  3NZ9 X;  3FY9 X;  4PTJ A;  4ELH A;  1QZF A;  3F8Z A;  1DRA A;  2FZI A;  1RX5 A;  4PSY A;  2ANQ A;  3TQB A;  1DF7 A;  4XE6 X;  1SEJ A;  4KM0 A;  4M7U A;  4DPH A;  3F0X X;  4KBN A;  3LG4 A;  4GH8 A;  2W9G A;  3QYO A;  3SRU X;  4CD2 A;  1DR7 A;  3E0B A;  3FQZ A;  4HOF A;  3FRB X;  5U26 A;  3INV A;  4OR7 A;  4DDR A;  3QL0 A;  1J3J A;  3HBB A;  1MVS A;  1AO8 A;  2L28 A;  1AI9 A;  4G8Z X;  3F0S X;  2W9S A;  3D84 X;  3EEJ A;  3SRR X;  5HUI A;  1RX9 A;  1IA2 A;  3SRQ X;  1J3K A;  3NZD A;  3GHC A;  3K74 A;  3QG2 A;  2AZN A;  3FRD X;  4H98 A;  2P4G A;  4IXF X;  1JOM A;  3NU0 A;  3NTZ A;  3EIG A;  1DLS A;  1DRB A;  4I1N A;  5HQY A;  4IXE D;  1RX2 A;  3TD8 A;  4IXG X;  3S3V A;  2FZH A;  2DHF A;  3FQO A;  2OIP A;  4KJL A;  4P66 A;  2O7P A;  1DAJ A;  3JSU A;  1MVT A;  3IRN A;  4OSG A;  4H97 A;  2C2S A;  4XEC X;  4RGC A;  3IRM A;  1RC4 A;  3EX8 A;  1DLR A;  3FS6 A;  3DL5 A;  3F0B X;  4M2X A;  4Q67 A;  1HFQ A;  3R33 A;  5EAJ A;  2BLA A;  2GD9 A;  2ITH A;  2W9T A;  4PSS A;  3JVX A;  3KJR A;  2W3M A;  4X5F A;  3ROA A;  2BL9 A;  3KFY A;  3FYW X;  1RX7 A;  1RX1 A;  3UM6 A;  5HSR A;  4LAG X;  3DAU A;  4X5G A;  1CD2 A;  1DYJ A;  5ECC A;  1BZF A;  2FZJ A;  1DR2 A;  3NZB X;  1RG7 A;  3QLW A;  5HVE A;  3HJ3 A;  4PTH A;  3FQ0 A;  4KJJ A;  5CC9 A;  1RX3 A;  1DIU A;  1RA9 A;  3SR5 X;  3NXV A;  1DG5 A;  4DPD A;  4TU5 X;  2D0K A;  5HVB A;  1S3W A;  4NX6 A;  4ELF A;  1DDS A;  3JW3 A;  1RD7 A;  4KFJ A;  4QLE A;  3IX9 A;  4KNE A;  3GHV A; 
#chains in the Genus database with same CATH topology
 3M09 A;  3M08 A;  3CLB A;  1LY3 A;  1DG8 A;  1DRH A;  1DHF A;  3QGT A;  3NXT A;  4Q6A A;  4HA9 A;  3F8Y A;  2LF1 A;  3NZ6 X;  4EIZ A;  3TQ9 A;  2XW7 A;  3JWF A;  2HXV A;  3EEK A;  3EEL A;  4PST A;  4ELE A;  1S3U A;  2C2T A;  3FQF A;  4M6K A;  5ECX A;  4QJC A;  3QFX A;  2G6V A;  3NXO A;  3FRF X;  1RA8 A;  4I13 A;  5HF2 X;  1DYH A;  3IA5 A;  1DYI A;  3K47 A;  4X5H A;  1DIS A;  3FQC A;  4XRB A;  2CIG A;  3Q1H A;  2W3V A;  1PD8 A;  3SQY X;  3F0V X;  3IA4 A;  4Q0D A;  4LEK X;  3QLR A;  1CZ3 A;  5HF0 X;  3RO9 A;  3JWK A;  1M7A A;  3I3R A;  4G95 A;  3IRO A;  4QJZ D;  1RB3 A;  1RB2 A;  2ANO A;  3QLS A;  4XT4 A;  1DHI A;  1DR1 A;  5HQZ A;  1DYR A;  4KEB A;  3SRS X;  4M6J A;  3QLY A;  2W9H A;  3OAF A;  4ELG A;  4G3M A;  3QLZ A;  2W3A A;  5FDA A;  2BLB A;  4QI9 A;  3SH2 A;  3F0Q X;  8DFR A;  4KJK A;  1VJ3 A;  1OHJ A;  1RA2 A;  3CL9 A;  3NRR A;  1RX6 A;  4ELB A;  4ECK A;  3UM5 A;  1AOE A;  5HT4 A;  3EEM A;  4KD7 A;  3RG9 A;  3QL3 A;  1IA4 A;  1DDR A;  2CD2 A;  1E26 A;  3GYF A;  5HSU A;  1IA3 A;  3NZC X;  2W3B A;  3VCO A;  1JUV A;  3I8A X;  4QLG A;  3KY8 A;  2JYB A;  3K2H A;  5JA3 A;  3FL8 A;  3FQV A;  3NXR A;  3SRW X;  3CD2 A;  1LUD A;  3FRE X;  1DR6 A;  1RA3 A;  2KGK A;  1RF7 A;  2D5N A;  3NZA X;  4KY8 A;  5E8Q A;  4HOG A;  4PDJ A;  1DHJ A;  3OCH A;  3K45 A;  4HA7 A;  4KLX A;  3SAI A;  4DFR A;  4LAE X;  5HT5 A;  3DL6 A;  3SGY A;  1VDR A;  3SA1 A;  5HPB A;  1DRE A;  1IA1 A;  3F91 A;  1PD9 A;  3D80 A;  1KLK A;  2W3W A;  4Q0E A;  4QLF A;  2QK8 A;  2HM9 A;  3DG8 A;  3DRC A;  4DP3 A;  3NXX A;  4KY4 A;  1RA1 A;  5DFR A;  5DXV A;  3S9U A;  3FL9 A;  1J3I A;  4FHB A;  4KM2 A;  4KYA A;  3DGA A;  6DFR A;  4KL9 A;  3SA2 A;  1DR5 A;  3FY8 X;  3L3R A;  4XT8 A;  1DRF A;  4NX7 A;  4P3Q A;  3F0U X;  3ZPC A;  4FGG A;  3KGY A;  1LY4 A;  4EIL A;  1M79 A;  2OBC A;  1RH3 A;  1S3Y A;  4XT7 A;  2B3Z A;  1JOL A;  1TDR A;  1U72 A;  3FRA X;  2H2Q A;  1RE7 A;  5HI6 A;  5U27 A;  3JW5 A;  7DFR A;  5CCC A;  4M7V A;  3QYL A;  2INQ A;  4M6L A;  3GI2 A;  1DG7 A;  4HOE A;  3JWC A;  1U70 A;  4P68 A;  1KMS A;  1RX8 A;  1DR4 A;  1U71 A;  1S3V A;  3CSE A;  2HQP A;  4KAK A;  4X5I A;  3JTW A;  1BOZ A;  1M78 A;  2BLC A;  4H96 A;  2ZZA A;  4EJ1 A;  1KMV A;  2DRC A;  3ZPG A;  3GHW A;  1DR3 A;  1D1G A;  4XT6 A;  1OHK A;  3N0H A;  3UM8 A;  3TQ8 A;  1YHO A;  1HFP A;  4X5J A;  3DAT A;  4XT5 A;  3NXY A;  1ZDR A;  3TQA A;  4H95 A;  3QLX A;  3DFR A;  1RX4 A;  4LAH X;  3FYV X;  4EIG A;  4P3R A;  4QHV A;  5JG0 X;  1PDB A;  3KJS A;  3JWM A;  1HFR A;  3S7A A;  4FGH A;  3NZ9 X;  3FY9 X;  4PTJ A;  4ELH A;  1QZF A;  3F8Z A;  1DRA A;  2FZI A;  1RX5 A;  4PSY A;  2ANQ A;  3TQB A;  1DF7 A;  4XE6 X;  1SEJ A;  4KM0 A;  4M7U A;  4DPH A;  3F0X X;  4KBN A;  3LG4 A;  4GH8 A;  2W9G A;  3QYO A;  3SRU X;  4CD2 A;  1DR7 A;  3E0B A;  3FQZ A;  4HOF A;  3FRB X;  5U26 A;  3INV A;  4OR7 A;  4DDR A;  3QL0 A;  1J3J A;  3HBB A;  1MVS A;  1AO8 A;  2L28 A;  1AI9 A;  4G8Z X;  3F0S X;  2W9S A;  3D84 X;  3EEJ A;  3SRR X;  5HUI A;  1RX9 A;  1IA2 A;  3SRQ X;  1J3K A;  3NZD A;  3GHC A;  3K74 A;  3QG2 A;  2AZN A;  3FRD X;  4H98 A;  2P4G A;  4IXF X;  1JOM A;  3NU0 A;  3NTZ A;  3EIG A;  1DLS A;  1DRB A;  4I1N A;  5HQY A;  4IXE D;  1RX2 A;  3TD8 A;  4IXG X;  3S3V A;  2FZH A;  2DHF A;  3FQO A;  2OIP A;  4KJL A;  4P66 A;  2O7P A;  1DAJ A;  3JSU A;  1MVT A;  3IRN A;  4OSG A;  4H97 A;  2C2S A;  4XEC X;  4RGC A;  3IRM A;  1RC4 A;  3EX8 A;  1DLR A;  3FS6 A;  3DL5 A;  3F0B X;  4M2X A;  4Q67 A;  1HFQ A;  3R33 A;  5EAJ A;  2BLA A;  2GD9 A;  2ITH A;  2W9T A;  4PSS A;  3JVX A;  3KJR A;  2W3M A;  4X5F A;  3ROA A;  2BL9 A;  3KFY A;  3FYW X;  1RX7 A;  1RX1 A;  3UM6 A;  5HSR A;  4LAG X;  3DAU A;  4X5G A;  1CD2 A;  1DYJ A;  5ECC A;  1BZF A;  2FZJ A;  1DR2 A;  3NZB X;  1RG7 A;  3QLW A;  5HVE A;  3HJ3 A;  4PTH A;  3FQ0 A;  4KJJ A;  5CC9 A;  1RX3 A;  1DIU A;  1RA9 A;  3SR5 X;  3NXV A;  1DG5 A;  4DPD A;  4TU5 X;  2D0K A;  5HVB A;  1S3W A;  4NX6 A;  4ELF A;  1DDS A;  3JW3 A;  1RD7 A;  4KFJ A;  4QLE A;  3IX9 A;  4KNE A;  3GHV A; 
#chains in the Genus database with same CATH homology
 3M09 A;  3M08 A;  3CLB A;  1LY3 A;  1DG8 A;  1DRH A;  1DHF A;  3QGT A;  3NXT A;  4Q6A A;  4HA9 A;  3F8Y A;  2LF1 A;  3NZ6 X;  4EIZ A;  3TQ9 A;  2XW7 A;  3JWF A;  2HXV A;  3EEK A;  3EEL A;  4PST A;  4ELE A;  1S3U A;  2C2T A;  3FQF A;  4M6K A;  5ECX A;  4QJC A;  3QFX A;  2G6V A;  3NXO A;  3FRF X;  1RA8 A;  4I13 A;  5HF2 X;  1DYH A;  3IA5 A;  1DYI A;  3K47 A;  4X5H A;  1DIS A;  3FQC A;  4XRB A;  2CIG A;  3Q1H A;  2W3V A;  1PD8 A;  3SQY X;  3F0V X;  3IA4 A;  4Q0D A;  4LEK X;  3QLR A;  1CZ3 A;  5HF0 X;  3RO9 A;  3JWK A;  1M7A A;  3I3R A;  4G95 A;  3IRO A;  4QJZ D;  1RB3 A;  1RB2 A;  2ANO A;  3QLS A;  4XT4 A;  1DHI A;  1DR1 A;  5HQZ A;  1DYR A;  4KEB A;  3SRS X;  4M6J A;  3QLY A;  2W9H A;  3OAF A;  4ELG A;  4G3M A;  3QLZ A;  2W3A A;  5FDA A;  2BLB A;  4QI9 A;  3SH2 A;  3F0Q X;  8DFR A;  4KJK A;  1VJ3 A;  1OHJ A;  1RA2 A;  3CL9 A;  3NRR A;  1RX6 A;  4ELB A;  4ECK A;  3UM5 A;  1AOE A;  5HT4 A;  3EEM A;  4KD7 A;  3RG9 A;  3QL3 A;  1IA4 A;  1DDR A;  2CD2 A;  1E26 A;  3GYF A;  5HSU A;  1IA3 A;  3NZC X;  2W3B A;  3VCO A;  1JUV A;  3I8A X;  4QLG A;  3KY8 A;  2JYB A;  3K2H A;  5JA3 A;  3FL8 A;  3FQV A;  3NXR A;  3SRW X;  3CD2 A;  1LUD A;  3FRE X;  1DR6 A;  1RA3 A;  2KGK A;  1RF7 A;  2D5N A;  3NZA X;  4KY8 A;  5E8Q A;  4HOG A;  4PDJ A;  1DHJ A;  3OCH A;  3K45 A;  4HA7 A;  4KLX A;  3SAI A;  4DFR A;  4LAE X;  5HT5 A;  3DL6 A;  3SGY A;  1VDR A;  3SA1 A;  5HPB A;  1DRE A;  1IA1 A;  3F91 A;  1PD9 A;  3D80 A;  1KLK A;  2W3W A;  4Q0E A;  4QLF A;  2QK8 A;  2HM9 A;  3DG8 A;  3DRC A;  4DP3 A;  3NXX A;  4KY4 A;  1RA1 A;  5DFR A;  5DXV A;  3S9U A;  3FL9 A;  1J3I A;  4FHB A;  4KM2 A;  4KYA A;  3DGA A;  6DFR A;  4KL9 A;  3SA2 A;  1DR5 A;  3FY8 X;  3L3R A;  4XT8 A;  1DRF A;  4NX7 A;  4P3Q A;  3F0U X;  3ZPC A;  4FGG A;  3KGY A;  1LY4 A;  4EIL A;  1M79 A;  2OBC A;  1RH3 A;  1S3Y A;  4XT7 A;  2B3Z A;  1JOL A;  1TDR A;  1U72 A;  3FRA X;  2H2Q A;  1RE7 A;  5HI6 A;  5U27 A;  3JW5 A;  7DFR A;  5CCC A;  4M7V A;  3QYL A;  2INQ A;  4M6L A;  3GI2 A;  1DG7 A;  4HOE A;  3JWC A;  1U70 A;  4P68 A;  1KMS A;  1RX8 A;  1DR4 A;  1U71 A;  1S3V A;  3CSE A;  2HQP A;  4KAK A;  4X5I A;  3JTW A;  1BOZ A;  1M78 A;  2BLC A;  4H96 A;  2ZZA A;  4EJ1 A;  1KMV A;  2DRC A;  3ZPG A;  3GHW A;  1DR3 A;  1D1G A;  4XT6 A;  1OHK A;  3N0H A;  3UM8 A;  3TQ8 A;  1YHO A;  1HFP A;  4X5J A;  3DAT A;  4XT5 A;  3NXY A;  1ZDR A;  3TQA A;  4H95 A;  3QLX A;  3DFR A;  1RX4 A;  4LAH X;  3FYV X;  4EIG A;  4P3R A;  4QHV A;  5JG0 X;  1PDB A;  3KJS A;  3JWM A;  1HFR A;  3S7A A;  4FGH A;  3NZ9 X;  3FY9 X;  4PTJ A;  4ELH A;  1QZF A;  3F8Z A;  1DRA A;  2FZI A;  1RX5 A;  4PSY A;  2ANQ A;  3TQB A;  1DF7 A;  4XE6 X;  1SEJ A;  4KM0 A;  4M7U A;  4DPH A;  3F0X X;  4KBN A;  3LG4 A;  4GH8 A;  2W9G A;  3QYO A;  3SRU X;  4CD2 A;  1DR7 A;  3E0B A;  3FQZ A;  4HOF A;  3FRB X;  5U26 A;  3INV A;  4OR7 A;  4DDR A;  3QL0 A;  1J3J A;  3HBB A;  1MVS A;  1AO8 A;  2L28 A;  1AI9 A;  4G8Z X;  3F0S X;  2W9S A;  3D84 X;  3EEJ A;  3SRR X;  5HUI A;  1RX9 A;  1IA2 A;  3SRQ X;  1J3K A;  3NZD A;  3GHC A;  3K74 A;  3QG2 A;  2AZN A;  3FRD X;  4H98 A;  2P4G A;  4IXF X;  1JOM A;  3NU0 A;  3NTZ A;  3EIG A;  1DLS A;  1DRB A;  4I1N A;  5HQY A;  4IXE D;  1RX2 A;  3TD8 A;  4IXG X;  3S3V A;  2FZH A;  2DHF A;  3FQO A;  2OIP A;  4KJL A;  4P66 A;  2O7P A;  1DAJ A;  3JSU A;  1MVT A;  3IRN A;  4OSG A;  4H97 A;  2C2S A;  4XEC X;  4RGC A;  3IRM A;  1RC4 A;  3EX8 A;  1DLR A;  3FS6 A;  3DL5 A;  3F0B X;  4M2X A;  4Q67 A;  1HFQ A;  3R33 A;  5EAJ A;  2BLA A;  2GD9 A;  2ITH A;  2W9T A;  4PSS A;  3JVX A;  3KJR A;  2W3M A;  4X5F A;  3ROA A;  2BL9 A;  3KFY A;  3FYW X;  1RX7 A;  1RX1 A;  3UM6 A;  5HSR A;  4LAG X;  3DAU A;  4X5G A;  1CD2 A;  1DYJ A;  5ECC A;  1BZF A;  2FZJ A;  1DR2 A;  3NZB X;  1RG7 A;  3QLW A;  5HVE A;  3HJ3 A;  4PTH A;  3FQ0 A;  4KJJ A;  5CC9 A;  1RX3 A;  1DIU A;  1RA9 A;  3SR5 X;  3NXV A;  1DG5 A;  4DPD A;  4TU5 X;  2D0K A;  5HVB A;  1S3W A;  4NX6 A;  4ELF A;  1DDS A;  3JW3 A;  1RD7 A;  4KFJ A;  4QLE A;  3IX9 A;  4KNE A;  3GHV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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