1DRFA

Crystal structure of human dihydrofolate reductase complexed with folate
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human dihydrofolate reductase complexed with folate.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase (ch-nh(d)-nad or nadp(a))
source organism Homo sapiens
total genus 51
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1990-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1drfA00
1AO8A 1CD2A 4HOEA 3GHWA 1AI9A 2G6VA 4H96A 4KNEA 3K74A 3ZPGA 3GYFA 4KYAA 4EIGA 1RC4A 4QJCA 3TQ8A 4XE6X 3DAUA 3FYVX 3SA1A 5ECXA 3S3VA 3SR5X 1DAJA 1DLRA 1VJ3A 3FQCA 2DHFA 3QLXA 3FRFX 1IA4A 4HA9A 1DYJA 3GHCA 3RG9A 3M09A 3GI2A 1RX1A 2LF1A 1DR2A 4KJKA 3FY8X 5U26A 3NZCX 5HF2X 3NRRA 2W3AA 4P3QA 1DR7A 2W9TA 3FQZA 4HOFA 1DR4A 1U70A 4PSTA 1DDRA 4XT7A 5HT4A 1CZ3A 1JUVA 2ZZAA 4TU5X 4H97A 5CCCA 3UM8A 2W3WA 1RA3A 3SH2A 2O7PA 2FZIA 2JYBA 3JWKA 4OR7A 6DFRA 4KFJA 3QYOA 4M6JA 3QL0A 1M79A 1RA8A 4FHBA 5DFRA 1DRHA 3NXXA 1VDRA 1BZFA 4FGHA 3NXTA 5HSUA 1RX2A 4X5HA 4IXGX 1RX9A 4LAHX 3DATA 3IX9A 2ANOA 3JVXA 3TQAA 3EEKA 3QL3A 4NX7A 4RGCA 5HVEA 3KGYA 1DG5A 3F91A 2FZJA 3RO9A 4PTHA 3EEJA 1JOLA 3F0VX 1S3YA 3K45A 4ELHA 3IROA 1QZFA 1RA2A 3CSEA 4H98A 1M78A 1RB3A 4KM0A 2HXVA 4LAGX 1RH3A 2B3ZA 3NU0A 2FZHA 1MVSA 3TQBA 2HQPA 1HFQA 2AZNA 1HFRA 3OCHA 4P68A 5HT5A 5HQYA 2C2TA 4KAKA 1J3JA 5HPBA 5HUIA 1M7AA 3R33A 3LG4A 3NXRA 1DR5A 1RE7A 3QLYA 1DR3A 3QYLA 3I3RA 4XT8A 3SRQX 1ZDRA 4ELEA 4KLXA 1U71A 3NZBX 3FREX 1DHFA 3FY9X 4XT4A 3JTWA 1JOMA 4M7UA 3F0SX 8DFRA 3JWMA 1DLSA 3NXOA 3FL9A 3UM5A 4QHVA 1HFPA 2INQA 4PSSA 4IXED 3EEMA 3SRUX 1RD7A 3ROAA 1LY4A 1DRBA 3N0HA 4XT5A 1KMSA 4DPHA 3E0BA 3IRNA 3F0QX 3DGAA 1KLKA 3EX8A 1DYIA 3F0XX 3KJSA 5HQZA 2W9GA 1DHJA 2P4GA 3QLSA 3TD8A 3K2HA 1RF7A 3JWFA 1DIUA 4EILA 1RA9A 1OHKA 2W9HA 3GHVA 3SAIA 1DREA 2C2SA 4LAEX 4ELGA 1BOZA 1RX8A 1LY3A 2OIPA 3CLBA 3JW5A 4KBNA 4KY8A 4HA7A 4QJZD 1TDRA 2BLCA 3FYWX 1DHIA 1S3WA 3EELA 2BLAA 3FQVA 3NXVA 1S3VA 3FQOA 5JA3A 3F0BX 3CL9A 2ANQA 4P66A 4PDJA 1DYHA 4DDRA 4G8ZX 1SEJA 4QLFA 4DFRA 1PDBA 3DL5A 1YHOA 4Q0DA 3NZ9X 3QLZA 2W9SA 4FGGA 4P3RA 4M2XA 2W3MA 2H2QA 4ECKA 3SA2A 1RB2A 5HSRA 3QLWA 1DR1A 3INVA 1PD8A 2W3VA 3JWCA 1IA3A 1J3IA 4DP3A 3ZPCA 1OHJA 2W3BA 3DFRA 3KFYA 4X5IA 3TQ9A 1DYRA 1DF7A 4KD7A 5U27A 3DG8A 2CD2A 3EIGA 4GH8A 2XW7A 3SRWX 3Q1HA 3HJ3A 3SRSX 4PSYA 4XECX 1DG7A 3F8ZA 3FL8A 1LUDA 4QLGA 5FDAA 4Q67A 5HVBA 3IA5A 1RX3A 3NZ6X 5JG0X 1RA1A 4CD2A 3NXYA 4M6KA 3S9UA 3VCOA 3FRAX 5HI6A 2HM9A 2BLBA 4XRBA 3FS6A 4QI9A 3QG2A 3SQYX 2GD9A 4EJ1A 1IA1A 4KM2A 7DFRA 2QK8A 1MVTA 1RX6A 3KJRA 3NZAX 3NZDA 2D0KA 4I1NA 3FQ0A 5HF0X 4OSGA 1DG8A 1RG7A 3FQFA 3UM6A 4KL9A 4I13A 3D84X 1RX4A 1KMVA 1DRAA 4KJLA 3JW3A 4KY4A 4DPDA 4M6LA 4X5JA 3DRCA 3IA4A 3I8AX 4G95A 3F0UX 5ECCA 3QFXA 4EIZA 3JSUA 3OAFA 1AOEA 1RX5A 4KJJA 2OBCA 2L28A 3L3RA 1S3UA 3F8YA 3QLRA 4XT6A 3IRMA 4IXFX 4ELBA 1DR6A 3SRRX 5CC9A 2D5NA 4H95A 3D80A 1RX7A 2KGKA 4NX6A 5DXVA 1DDSA 3S7AA 4Q0EA 4G3MA 3SGYA 4KEBA 1J3KA 4X5GA 1DISA 5EAJA 4Q6AA 3HBBA 3DL6A 3QGTA 3FRDX 3NTZA 1PD9A 4M7VA 1U72A 4X5FA 4QLEA 2BL9A 1IA2A 1DRFA 3K47A 4ELFA 3CD2A 3FRBX 2ITHA 2CIGA 4LEKX 4HOGA 1E26A 4PTJA 1D1GA 3KY8A 3M08A 5E8QA 2DRCA
chains in the Genus database with same CATH superfamily
1AO8A 1CD2A 4HOEA 3GHWA 1AI9A 2G6VA 4H96A 4KNEA 3K74A 3ZPGA 3GYFA 4KYAA 4EIGA 1RC4A 4QJCA 3TQ8A 4XE6X 3DAUA 3FYVX 3SA1A 5ECXA 3S3VA 3SR5X 1DAJA 1DLRA 1VJ3A 3FQCA 2DHFA 3QLXA 3FRFX 1IA4A 4HA9A 1DYJA 3GHCA 3RG9A 3M09A 3GI2A 1RX1A 2LF1A 1DR2A 4KJKA 3FY8X 5U26A 3NZCX 5HF2X 3NRRA 2W3AA 4P3QA 1DR7A 2W9TA 3FQZA 4HOFA 1DR4A 1U70A 4PSTA 1DDRA 4XT7A 5HT4A 1CZ3A 1JUVA 2ZZAA 4TU5X 4H97A 5CCCA 3UM8A 2W3WA 1RA3A 3SH2A 2O7PA 2FZIA 2JYBA 3JWKA 4OR7A 6DFRA 4KFJA 3QYOA 4M6JA 3QL0A 1M79A 1RA8A 4FHBA 5DFRA 1DRHA 3NXXA 1VDRA 1BZFA 4FGHA 3NXTA 5HSUA 1RX2A 4X5HA 4IXGX 1RX9A 4LAHX 3DATA 3IX9A 2ANOA 3JVXA 3TQAA 3EEKA 3QL3A 4NX7A 4RGCA 5HVEA 3KGYA 1DG5A 3F91A 2FZJA 3RO9A 4PTHA 3EEJA 1JOLA 3F0VX 1S3YA 3K45A 4ELHA 3IROA 1QZFA 1RA2A 3CSEA 4H98A 1M78A 1RB3A 4KM0A 2HXVA 4LAGX 1RH3A 2B3ZA 3NU0A 2FZHA 1MVSA 3TQBA 2HQPA 1HFQA 2AZNA 1HFRA 3OCHA 4P68A 5HT5A 5HQYA 2C2TA 4KAKA 1J3JA 5HPBA 5HUIA 1M7AA 3R33A 3LG4A 3NXRA 1DR5A 1RE7A 3QLYA 1DR3A 3QYLA 3I3RA 4XT8A 3SRQX 1ZDRA 4ELEA 4KLXA 1U71A 3NZBX 3FREX 1DHFA 3FY9X 4XT4A 3JTWA 1JOMA 4M7UA 3F0SX 8DFRA 3JWMA 1DLSA 3NXOA 3FL9A 3UM5A 4QHVA 1HFPA 2INQA 4PSSA 4IXED 3EEMA 3SRUX 1RD7A 3ROAA 1LY4A 1DRBA 3N0HA 4XT5A 1KMSA 4DPHA 3E0BA 3IRNA 3F0QX 3DGAA 1KLKA 3EX8A 1DYIA 3F0XX 3KJSA 5HQZA 2W9GA 1DHJA 2P4GA 3QLSA 3TD8A 3K2HA 1RF7A 3JWFA 1DIUA 4EILA 1RA9A 1OHKA 2W9HA 3GHVA 3SAIA 1DREA 2C2SA 4LAEX 4ELGA 1BOZA 1RX8A 1LY3A 2OIPA 3CLBA 3JW5A 4KBNA 4KY8A 4HA7A 4QJZD 1TDRA 2BLCA 3FYWX 1DHIA 1S3WA 3EELA 2BLAA 3FQVA 3NXVA 1S3VA 3FQOA 5JA3A 3F0BX 3CL9A 2ANQA 4P66A 4PDJA 1DYHA 4DDRA 4G8ZX 1SEJA 4QLFA 4DFRA 1PDBA 3DL5A 1YHOA 4Q0DA 3NZ9X 3QLZA 2W9SA 4FGGA 4P3RA 4M2XA 2W3MA 2H2QA 4ECKA 3SA2A 1RB2A 5HSRA 3QLWA 1DR1A 3INVA 1PD8A 2W3VA 3JWCA 1IA3A 1J3IA 4DP3A 3ZPCA 1OHJA 2W3BA 3DFRA 3KFYA 4X5IA 3TQ9A 1DYRA 1DF7A 4KD7A 5U27A 3DG8A 2CD2A 3EIGA 4GH8A 2XW7A 3SRWX 3Q1HA 3HJ3A 3SRSX 4PSYA 4XECX 1DG7A 3F8ZA 3FL8A 1LUDA 4QLGA 5FDAA 4Q67A 5HVBA 3IA5A 1RX3A 3NZ6X 5JG0X 1RA1A 4CD2A 3NXYA 4M6KA 3S9UA 3VCOA 3FRAX 5HI6A 2HM9A 2BLBA 4XRBA 3FS6A 4QI9A 3QG2A 3SQYX 2GD9A 4EJ1A 1IA1A 4KM2A 7DFRA 2QK8A 1MVTA 1RX6A 3KJRA 3NZAX 3NZDA 2D0KA 4I1NA 3FQ0A 5HF0X 4OSGA 1DG8A 1RG7A 3FQFA 3UM6A 4KL9A 4I13A 3D84X 1RX4A 1KMVA 1DRAA 4KJLA 3JW3A 4KY4A 4DPDA 4M6LA 4X5JA 3DRCA 3IA4A 3I8AX 4G95A 3F0UX 5ECCA 3QFXA 4EIZA 3JSUA 3OAFA 1AOEA 1RX5A 4KJJA 2OBCA 2L28A 3L3RA 1S3UA 3F8YA 3QLRA 4XT6A 3IRMA 4IXFX 4ELBA 1DR6A 3SRRX 5CC9A 2D5NA 4H95A 3D80A 1RX7A 2KGKA 4NX6A 5DXVA 1DDSA 3S7AA 4Q0EA 4G3MA 3SGYA 4KEBA 1J3KA 4X5GA 1DISA 5EAJA 4Q6AA 3HBBA 3DL6A 3QGTA 3FRDX 3NTZA 1PD9A 4M7VA 1U72A 4X5FA 4QLEA 2BL9A 1IA2A 1DRFA 3K47A 4ELFA 3CD2A 3FRBX 2ITHA 2CIGA 4LEKX 4HOGA 1E26A 4PTJA 1D1GA 3KY8A 3M08A 5E8QA 2DRCA
chains in the Genus database with same CATH topology
1AO8A 1CD2A 4HOEA 3GHWA 1AI9A 2G6VA 4H96A 4KNEA 3K74A 3ZPGA 3GYFA 4KYAA 4EIGA 1RC4A 4QJCA 3TQ8A 4XE6X 3DAUA 3FYVX 3SA1A 5ECXA 3S3VA 3SR5X 1DAJA 1DLRA 1VJ3A 3FQCA 2DHFA 3QLXA 3FRFX 1IA4A 4HA9A 1DYJA 3GHCA 3RG9A 3M09A 3GI2A 1RX1A 2LF1A 1DR2A 4KJKA 3FY8X 5U26A 3NZCX 5HF2X 3NRRA 2W3AA 4P3QA 1DR7A 2W9TA 3FQZA 4HOFA 1DR4A 1U70A 4PSTA 1DDRA 4XT7A 5HT4A 1CZ3A 1JUVA 2ZZAA 4TU5X 4H97A 5CCCA 3UM8A 2W3WA 1RA3A 3SH2A 2O7PA 2FZIA 2JYBA 3JWKA 4OR7A 6DFRA 4KFJA 3QYOA 4M6JA 3QL0A 1M79A 1RA8A 4FHBA 5DFRA 1DRHA 3NXXA 1VDRA 1BZFA 4FGHA 3NXTA 5HSUA 1RX2A 4X5HA 4IXGX 1RX9A 4LAHX 3DATA 3IX9A 2ANOA 3JVXA 3TQAA 3EEKA 3QL3A 4NX7A 4RGCA 5HVEA 3KGYA 1DG5A 3F91A 2FZJA 3RO9A 4PTHA 3EEJA 1JOLA 3F0VX 1S3YA 3K45A 4ELHA 3IROA 1QZFA 1RA2A 3CSEA 4H98A 1M78A 1RB3A 4KM0A 2HXVA 4LAGX 1RH3A 2B3ZA 3NU0A 2FZHA 1MVSA 3TQBA 2HQPA 1HFQA 2AZNA 1HFRA 3OCHA 4P68A 5HT5A 5HQYA 2C2TA 4KAKA 1J3JA 5HPBA 5HUIA 1M7AA 3R33A 3LG4A 3NXRA 1DR5A 1RE7A 3QLYA 1DR3A 3QYLA 3I3RA 4XT8A 3SRQX 1ZDRA 4ELEA 4KLXA 1U71A 3NZBX 3FREX 1DHFA 3FY9X 4XT4A 3JTWA 1JOMA 4M7UA 3F0SX 8DFRA 3JWMA 1DLSA 3NXOA 3FL9A 3UM5A 4QHVA 1HFPA 2INQA 4PSSA 4IXED 3EEMA 3SRUX 1RD7A 3ROAA 1LY4A 1DRBA 3N0HA 4XT5A 1KMSA 4DPHA 3E0BA 3IRNA 3F0QX 3DGAA 1KLKA 3EX8A 1DYIA 3F0XX 3KJSA 5HQZA 2W9GA 1DHJA 2P4GA 3QLSA 3TD8A 3K2HA 1RF7A 3JWFA 1DIUA 4EILA 1RA9A 1OHKA 2W9HA 3GHVA 3SAIA 1DREA 2C2SA 4LAEX 4ELGA 1BOZA 1RX8A 1LY3A 2OIPA 3CLBA 3JW5A 4KBNA 4KY8A 4HA7A 4QJZD 1TDRA 2BLCA 3FYWX 1DHIA 1S3WA 3EELA 2BLAA 3FQVA 3NXVA 1S3VA 3FQOA 5JA3A 3F0BX 3CL9A 2ANQA 4P66A 4PDJA 1DYHA 4DDRA 4G8ZX 1SEJA 4QLFA 4DFRA 1PDBA 3DL5A 1YHOA 4Q0DA 3NZ9X 3QLZA 2W9SA 4FGGA 4P3RA 4M2XA 2W3MA 2H2QA 4ECKA 3SA2A 1RB2A 5HSRA 3QLWA 1DR1A 3INVA 1PD8A 2W3VA 3JWCA 1IA3A 1J3IA 4DP3A 3ZPCA 1OHJA 2W3BA 3DFRA 3KFYA 4X5IA 3TQ9A 1DYRA 1DF7A 4KD7A 5U27A 3DG8A 2CD2A 3EIGA 4GH8A 2XW7A 3SRWX 3Q1HA 3HJ3A 3SRSX 4PSYA 4XECX 1DG7A 3F8ZA 3FL8A 1LUDA 4QLGA 5FDAA 4Q67A 5HVBA 3IA5A 1RX3A 3NZ6X 5JG0X 1RA1A 4CD2A 3NXYA 4M6KA 3S9UA 3VCOA 3FRAX 5HI6A 2HM9A 2BLBA 4XRBA 3FS6A 4QI9A 3QG2A 3SQYX 2GD9A 4EJ1A 1IA1A 4KM2A 7DFRA 2QK8A 1MVTA 1RX6A 3KJRA 3NZAX 3NZDA 2D0KA 4I1NA 3FQ0A 5HF0X 4OSGA 1DG8A 1RG7A 3FQFA 3UM6A 4KL9A 4I13A 3D84X 1RX4A 1KMVA 1DRAA 4KJLA 3JW3A 4KY4A 4DPDA 4M6LA 4X5JA 3DRCA 3IA4A 3I8AX 4G95A 3F0UX 5ECCA 3QFXA 4EIZA 3JSUA 3OAFA 1AOEA 1RX5A 4KJJA 2OBCA 2L28A 3L3RA 1S3UA 3F8YA 3QLRA 4XT6A 3IRMA 4IXFX 4ELBA 1DR6A 3SRRX 5CC9A 2D5NA 4H95A 3D80A 1RX7A 2KGKA 4NX6A 5DXVA 1DDSA 3S7AA 4Q0EA 4G3MA 3SGYA 4KEBA 1J3KA 4X5GA 1DISA 5EAJA 4Q6AA 3HBBA 3DL6A 3QGTA 3FRDX 3NTZA 1PD9A 4M7VA 1U72A 4X5FA 4QLEA 2BL9A 1IA2A 1DRFA 3K47A 4ELFA 3CD2A 3FRBX 2ITHA 2CIGA 4LEKX 4HOGA 1E26A 4PTJA 1D1GA 3KY8A 3M08A 5E8QA 2DRCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AO8 A;  1CD2 A;  4HOE A;  3GHW A;  1AI9 A;  2G6V A;  4H96 A;  4KNE A;  3K74 A;  3ZPG A;  3GYF A;  4KYA A;  4EIG A;  1RC4 A;  4QJC A;  3TQ8 A;  4XE6 X;  3DAU A;  3FYV X;  3SA1 A;  5ECX A;  3S3V A;  3SR5 X;  1DAJ A;  1DLR A;  1VJ3 A;  3FQC A;  2DHF A;  3QLX A;  3FRF X;  1IA4 A;  4HA9 A;  1DYJ A;  3GHC A;  3RG9 A;  3M09 A;  3GI2 A;  1RX1 A;  2LF1 A;  1DR2 A;  4KJK A;  3FY8 X;  5U26 A;  3NZC X;  5HF2 X;  3NRR A;  2W3A A;  4P3Q A;  1DR7 A;  2W9T A;  3FQZ A;  4HOF A;  1DR4 A;  1U70 A;  4PST A;  1DDR A;  4XT7 A;  5HT4 A;  1CZ3 A;  1JUV A;  2ZZA A;  4TU5 X;  4H97 A;  5CCC A;  3UM8 A;  2W3W A;  1RA3 A;  3SH2 A;  2O7P A;  2FZI A;  2JYB A;  3JWK A;  4OR7 A;  6DFR A;  4KFJ A;  3QYO A;  4M6J A;  3QL0 A;  1M79 A;  1RA8 A;  4FHB A;  5DFR A;  1DRH A;  3NXX A;  1VDR A;  1BZF A;  4FGH A;  3NXT A;  5HSU A;  1RX2 A;  4X5H A;  4IXG X;  1RX9 A;  4LAH X;  3DAT A;  3IX9 A;  2ANO A;  3JVX A;  3TQA A;  3EEK A;  3QL3 A;  4NX7 A;  4RGC A;  5HVE A;  3KGY A;  1DG5 A;  3F91 A;  2FZJ A;  3RO9 A;  4PTH A;  3EEJ A;  1JOL A;  3F0V X;  1S3Y A;  3K45 A;  4ELH A;  3IRO A;  1QZF A;  1RA2 A;  3CSE A;  4H98 A;  1M78 A;  1RB3 A;  4KM0 A;  2HXV A;  4LAG X;  1RH3 A;  2B3Z A;  3NU0 A;  2FZH A;  1MVS A;  3TQB A;  2HQP A;  1HFQ A;  2AZN A;  1HFR A;  3OCH A;  4P68 A;  5HT5 A;  5HQY A;  2C2T A;  4KAK A;  1J3J A;  5HPB A;  5HUI A;  1M7A A;  3R33 A;  3LG4 A;  3NXR A;  1DR5 A;  1RE7 A;  3QLY A;  1DR3 A;  3QYL A;  3I3R A;  4XT8 A;  3SRQ X;  1ZDR A;  4ELE A;  4KLX A;  1U71 A;  3NZB X;  3FRE X;  1DHF A;  3FY9 X;  4XT4 A;  3JTW A;  1JOM A;  4M7U A;  3F0S X;  8DFR A;  3JWM A;  1DLS A;  3NXO A;  3FL9 A;  3UM5 A;  4QHV A;  1HFP A;  2INQ A;  4PSS A;  4IXE D;  3EEM A;  3SRU X;  1RD7 A;  3ROA A;  1LY4 A;  1DRB A;  3N0H A;  4XT5 A;  1KMS A;  4DPH A;  3E0B A;  3IRN A;  3F0Q X;  3DGA A;  1KLK A;  3EX8 A;  1DYI A;  3F0X X;  3KJS A;  5HQZ A;  2W9G A;  1DHJ A;  2P4G A;  3QLS A;  3TD8 A;  3K2H A;  1RF7 A;  3JWF A;  1DIU A;  4EIL A;  1RA9 A;  1OHK A;  2W9H A;  3GHV A;  3SAI A;  1DRE A;  2C2S A;  4LAE X;  4ELG A;  1BOZ A;  1RX8 A;  1LY3 A;  2OIP A;  3CLB A;  3JW5 A;  4KBN A;  4KY8 A;  4HA7 A;  4QJZ D;  1TDR A;  2BLC A;  3FYW X;  1DHI A;  1S3W A;  3EEL A;  2BLA A;  3FQV A;  3NXV A;  1S3V A;  3FQO A;  5JA3 A;  3F0B X;  3CL9 A;  2ANQ A;  4P66 A;  4PDJ A;  1DYH A;  4DDR A;  4G8Z X;  1SEJ A;  4QLF A;  4DFR A;  1PDB A;  3DL5 A;  1YHO A;  4Q0D A;  3NZ9 X;  3QLZ A;  2W9S A;  4FGG A;  4P3R A;  4M2X A;  2W3M A;  2H2Q A;  4ECK A;  3SA2 A;  1RB2 A;  5HSR A;  3QLW A;  1DR1 A;  3INV A;  1PD8 A;  2W3V A;  3JWC A;  1IA3 A;  1J3I A;  4DP3 A;  3ZPC A;  1OHJ A;  2W3B A;  3DFR A;  3KFY A;  4X5I A;  3TQ9 A;  1DYR A;  1DF7 A;  4KD7 A;  5U27 A;  3DG8 A;  2CD2 A;  3EIG A;  4GH8 A;  2XW7 A;  3SRW X;  3Q1H A;  3HJ3 A;  3SRS X;  4PSY A;  4XEC X;  1DG7 A;  3F8Z A;  3FL8 A;  1LUD A;  4QLG A;  5FDA A;  4Q67 A;  5HVB A;  3IA5 A;  1RX3 A;  3NZ6 X;  5JG0 X;  1RA1 A;  4CD2 A;  3NXY A;  4M6K A;  3S9U A;  3VCO A;  3FRA X;  5HI6 A;  2HM9 A;  2BLB A;  4XRB A;  3FS6 A;  4QI9 A;  3QG2 A;  3SQY X;  2GD9 A;  4EJ1 A;  1IA1 A;  4KM2 A;  7DFR A;  2QK8 A;  1MVT A;  1RX6 A;  3KJR A;  3NZA X;  3NZD A;  2D0K A;  4I1N A;  3FQ0 A;  5HF0 X;  4OSG A;  1DG8 A;  1RG7 A;  3FQF A;  3UM6 A;  4KL9 A;  4I13 A;  3D84 X;  1RX4 A;  1KMV A;  1DRA A;  4KJL A;  3JW3 A;  4KY4 A;  4DPD A;  4M6L A;  4X5J A;  3DRC A;  3IA4 A;  3I8A X;  4G95 A;  3F0U X;  5ECC A;  3QFX A;  4EIZ A;  3JSU A;  3OAF A;  1AOE A;  1RX5 A;  4KJJ A;  2OBC A;  2L28 A;  3L3R A;  1S3U A;  3F8Y A;  3QLR A;  4XT6 A;  3IRM A;  4IXF X;  4ELB A;  1DR6 A;  3SRR X;  5CC9 A;  2D5N A;  4H95 A;  3D80 A;  1RX7 A;  2KGK A;  4NX6 A;  5DXV A;  1DDS A;  3S7A A;  4Q0E A;  4G3M A;  3SGY A;  4KEB A;  1J3K A;  4X5G A;  1DIS A;  5EAJ A;  4Q6A A;  3HBB A;  3DL6 A;  3QGT A;  3FRD X;  3NTZ A;  1PD9 A;  4M7V A;  1U72 A;  4X5F A;  4QLE A;  2BL9 A;  1IA2 A;  1DRF A;  3K47 A;  4ELF A;  3CD2 A;  3FRB X;  2ITH A;  2CIG A;  4LEK X;  4HOG A;  1E26 A;  4PTJ A;  1D1G A;  3KY8 A;  3M08 A;  5E8Q A;  2DRC A; 
#chains in the Genus database with same CATH topology
 1AO8 A;  1CD2 A;  4HOE A;  3GHW A;  1AI9 A;  2G6V A;  4H96 A;  4KNE A;  3K74 A;  3ZPG A;  3GYF A;  4KYA A;  4EIG A;  1RC4 A;  4QJC A;  3TQ8 A;  4XE6 X;  3DAU A;  3FYV X;  3SA1 A;  5ECX A;  3S3V A;  3SR5 X;  1DAJ A;  1DLR A;  1VJ3 A;  3FQC A;  2DHF A;  3QLX A;  3FRF X;  1IA4 A;  4HA9 A;  1DYJ A;  3GHC A;  3RG9 A;  3M09 A;  3GI2 A;  1RX1 A;  2LF1 A;  1DR2 A;  4KJK A;  3FY8 X;  5U26 A;  3NZC X;  5HF2 X;  3NRR A;  2W3A A;  4P3Q A;  1DR7 A;  2W9T A;  3FQZ A;  4HOF A;  1DR4 A;  1U70 A;  4PST A;  1DDR A;  4XT7 A;  5HT4 A;  1CZ3 A;  1JUV A;  2ZZA A;  4TU5 X;  4H97 A;  5CCC A;  3UM8 A;  2W3W A;  1RA3 A;  3SH2 A;  2O7P A;  2FZI A;  2JYB A;  3JWK A;  4OR7 A;  6DFR A;  4KFJ A;  3QYO A;  4M6J A;  3QL0 A;  1M79 A;  1RA8 A;  4FHB A;  5DFR A;  1DRH A;  3NXX A;  1VDR A;  1BZF A;  4FGH A;  3NXT A;  5HSU A;  1RX2 A;  4X5H A;  4IXG X;  1RX9 A;  4LAH X;  3DAT A;  3IX9 A;  2ANO A;  3JVX A;  3TQA A;  3EEK A;  3QL3 A;  4NX7 A;  4RGC A;  5HVE A;  3KGY A;  1DG5 A;  3F91 A;  2FZJ A;  3RO9 A;  4PTH A;  3EEJ A;  1JOL A;  3F0V X;  1S3Y A;  3K45 A;  4ELH A;  3IRO A;  1QZF A;  1RA2 A;  3CSE A;  4H98 A;  1M78 A;  1RB3 A;  4KM0 A;  2HXV A;  4LAG X;  1RH3 A;  2B3Z A;  3NU0 A;  2FZH A;  1MVS A;  3TQB A;  2HQP A;  1HFQ A;  2AZN A;  1HFR A;  3OCH A;  4P68 A;  5HT5 A;  5HQY A;  2C2T A;  4KAK A;  1J3J A;  5HPB A;  5HUI A;  1M7A A;  3R33 A;  3LG4 A;  3NXR A;  1DR5 A;  1RE7 A;  3QLY A;  1DR3 A;  3QYL A;  3I3R A;  4XT8 A;  3SRQ X;  1ZDR A;  4ELE A;  4KLX A;  1U71 A;  3NZB X;  3FRE X;  1DHF A;  3FY9 X;  4XT4 A;  3JTW A;  1JOM A;  4M7U A;  3F0S X;  8DFR A;  3JWM A;  1DLS A;  3NXO A;  3FL9 A;  3UM5 A;  4QHV A;  1HFP A;  2INQ A;  4PSS A;  4IXE D;  3EEM A;  3SRU X;  1RD7 A;  3ROA A;  1LY4 A;  1DRB A;  3N0H A;  4XT5 A;  1KMS A;  4DPH A;  3E0B A;  3IRN A;  3F0Q X;  3DGA A;  1KLK A;  3EX8 A;  1DYI A;  3F0X X;  3KJS A;  5HQZ A;  2W9G A;  1DHJ A;  2P4G A;  3QLS A;  3TD8 A;  3K2H A;  1RF7 A;  3JWF A;  1DIU A;  4EIL A;  1RA9 A;  1OHK A;  2W9H A;  3GHV A;  3SAI A;  1DRE A;  2C2S A;  4LAE X;  4ELG A;  1BOZ A;  1RX8 A;  1LY3 A;  2OIP A;  3CLB A;  3JW5 A;  4KBN A;  4KY8 A;  4HA7 A;  4QJZ D;  1TDR A;  2BLC A;  3FYW X;  1DHI A;  1S3W A;  3EEL A;  2BLA A;  3FQV A;  3NXV A;  1S3V A;  3FQO A;  5JA3 A;  3F0B X;  3CL9 A;  2ANQ A;  4P66 A;  4PDJ A;  1DYH A;  4DDR A;  4G8Z X;  1SEJ A;  4QLF A;  4DFR A;  1PDB A;  3DL5 A;  1YHO A;  4Q0D A;  3NZ9 X;  3QLZ A;  2W9S A;  4FGG A;  4P3R A;  4M2X A;  2W3M A;  2H2Q A;  4ECK A;  3SA2 A;  1RB2 A;  5HSR A;  3QLW A;  1DR1 A;  3INV A;  1PD8 A;  2W3V A;  3JWC A;  1IA3 A;  1J3I A;  4DP3 A;  3ZPC A;  1OHJ A;  2W3B A;  3DFR A;  3KFY A;  4X5I A;  3TQ9 A;  1DYR A;  1DF7 A;  4KD7 A;  5U27 A;  3DG8 A;  2CD2 A;  3EIG A;  4GH8 A;  2XW7 A;  3SRW X;  3Q1H A;  3HJ3 A;  3SRS X;  4PSY A;  4XEC X;  1DG7 A;  3F8Z A;  3FL8 A;  1LUD A;  4QLG A;  5FDA A;  4Q67 A;  5HVB A;  3IA5 A;  1RX3 A;  3NZ6 X;  5JG0 X;  1RA1 A;  4CD2 A;  3NXY A;  4M6K A;  3S9U A;  3VCO A;  3FRA X;  5HI6 A;  2HM9 A;  2BLB A;  4XRB A;  3FS6 A;  4QI9 A;  3QG2 A;  3SQY X;  2GD9 A;  4EJ1 A;  1IA1 A;  4KM2 A;  7DFR A;  2QK8 A;  1MVT A;  1RX6 A;  3KJR A;  3NZA X;  3NZD A;  2D0K A;  4I1N A;  3FQ0 A;  5HF0 X;  4OSG A;  1DG8 A;  1RG7 A;  3FQF A;  3UM6 A;  4KL9 A;  4I13 A;  3D84 X;  1RX4 A;  1KMV A;  1DRA A;  4KJL A;  3JW3 A;  4KY4 A;  4DPD A;  4M6L A;  4X5J A;  3DRC A;  3IA4 A;  3I8A X;  4G95 A;  3F0U X;  5ECC A;  3QFX A;  4EIZ A;  3JSU A;  3OAF A;  1AOE A;  1RX5 A;  4KJJ A;  2OBC A;  2L28 A;  3L3R A;  1S3U A;  3F8Y A;  3QLR A;  4XT6 A;  3IRM A;  4IXF X;  4ELB A;  1DR6 A;  3SRR X;  5CC9 A;  2D5N A;  4H95 A;  3D80 A;  1RX7 A;  2KGK A;  4NX6 A;  5DXV A;  1DDS A;  3S7A A;  4Q0E A;  4G3M A;  3SGY A;  4KEB A;  1J3K A;  4X5G A;  1DIS A;  5EAJ A;  4Q6A A;  3HBB A;  3DL6 A;  3QGT A;  3FRD X;  3NTZ A;  1PD9 A;  4M7V A;  1U72 A;  4X5F A;  4QLE A;  2BL9 A;  1IA2 A;  1DRF A;  3K47 A;  4ELF A;  3CD2 A;  3FRB X;  2ITH A;  2CIG A;  4LEK X;  4HOG A;  1E26 A;  4PTJ A;  1D1G A;  3KY8 A;  3M08 A;  5E8Q A;  2DRC A; 
#chains in the Genus database with same CATH homology
 1AO8 A;  1CD2 A;  4HOE A;  3GHW A;  1AI9 A;  2G6V A;  4H96 A;  4KNE A;  3K74 A;  3ZPG A;  3GYF A;  4KYA A;  4EIG A;  1RC4 A;  4QJC A;  3TQ8 A;  4XE6 X;  3DAU A;  3FYV X;  3SA1 A;  5ECX A;  3S3V A;  3SR5 X;  1DAJ A;  1DLR A;  1VJ3 A;  3FQC A;  2DHF A;  3QLX A;  3FRF X;  1IA4 A;  4HA9 A;  1DYJ A;  3GHC A;  3RG9 A;  3M09 A;  3GI2 A;  1RX1 A;  2LF1 A;  1DR2 A;  4KJK A;  3FY8 X;  5U26 A;  3NZC X;  5HF2 X;  3NRR A;  2W3A A;  4P3Q A;  1DR7 A;  2W9T A;  3FQZ A;  4HOF A;  1DR4 A;  1U70 A;  4PST A;  1DDR A;  4XT7 A;  5HT4 A;  1CZ3 A;  1JUV A;  2ZZA A;  4TU5 X;  4H97 A;  5CCC A;  3UM8 A;  2W3W A;  1RA3 A;  3SH2 A;  2O7P A;  2FZI A;  2JYB A;  3JWK A;  4OR7 A;  6DFR A;  4KFJ A;  3QYO A;  4M6J A;  3QL0 A;  1M79 A;  1RA8 A;  4FHB A;  5DFR A;  1DRH A;  3NXX A;  1VDR A;  1BZF A;  4FGH A;  3NXT A;  5HSU A;  1RX2 A;  4X5H A;  4IXG X;  1RX9 A;  4LAH X;  3DAT A;  3IX9 A;  2ANO A;  3JVX A;  3TQA A;  3EEK A;  3QL3 A;  4NX7 A;  4RGC A;  5HVE A;  3KGY A;  1DG5 A;  3F91 A;  2FZJ A;  3RO9 A;  4PTH A;  3EEJ A;  1JOL A;  3F0V X;  1S3Y A;  3K45 A;  4ELH A;  3IRO A;  1QZF A;  1RA2 A;  3CSE A;  4H98 A;  1M78 A;  1RB3 A;  4KM0 A;  2HXV A;  4LAG X;  1RH3 A;  2B3Z A;  3NU0 A;  2FZH A;  1MVS A;  3TQB A;  2HQP A;  1HFQ A;  2AZN A;  1HFR A;  3OCH A;  4P68 A;  5HT5 A;  5HQY A;  2C2T A;  4KAK A;  1J3J A;  5HPB A;  5HUI A;  1M7A A;  3R33 A;  3LG4 A;  3NXR A;  1DR5 A;  1RE7 A;  3QLY A;  1DR3 A;  3QYL A;  3I3R A;  4XT8 A;  3SRQ X;  1ZDR A;  4ELE A;  4KLX A;  1U71 A;  3NZB X;  3FRE X;  1DHF A;  3FY9 X;  4XT4 A;  3JTW A;  1JOM A;  4M7U A;  3F0S X;  8DFR A;  3JWM A;  1DLS A;  3NXO A;  3FL9 A;  3UM5 A;  4QHV A;  1HFP A;  2INQ A;  4PSS A;  4IXE D;  3EEM A;  3SRU X;  1RD7 A;  3ROA A;  1LY4 A;  1DRB A;  3N0H A;  4XT5 A;  1KMS A;  4DPH A;  3E0B A;  3IRN A;  3F0Q X;  3DGA A;  1KLK A;  3EX8 A;  1DYI A;  3F0X X;  3KJS A;  5HQZ A;  2W9G A;  1DHJ A;  2P4G A;  3QLS A;  3TD8 A;  3K2H A;  1RF7 A;  3JWF A;  1DIU A;  4EIL A;  1RA9 A;  1OHK A;  2W9H A;  3GHV A;  3SAI A;  1DRE A;  2C2S A;  4LAE X;  4ELG A;  1BOZ A;  1RX8 A;  1LY3 A;  2OIP A;  3CLB A;  3JW5 A;  4KBN A;  4KY8 A;  4HA7 A;  4QJZ D;  1TDR A;  2BLC A;  3FYW X;  1DHI A;  1S3W A;  3EEL A;  2BLA A;  3FQV A;  3NXV A;  1S3V A;  3FQO A;  5JA3 A;  3F0B X;  3CL9 A;  2ANQ A;  4P66 A;  4PDJ A;  1DYH A;  4DDR A;  4G8Z X;  1SEJ A;  4QLF A;  4DFR A;  1PDB A;  3DL5 A;  1YHO A;  4Q0D A;  3NZ9 X;  3QLZ A;  2W9S A;  4FGG A;  4P3R A;  4M2X A;  2W3M A;  2H2Q A;  4ECK A;  3SA2 A;  1RB2 A;  5HSR A;  3QLW A;  1DR1 A;  3INV A;  1PD8 A;  2W3V A;  3JWC A;  1IA3 A;  1J3I A;  4DP3 A;  3ZPC A;  1OHJ A;  2W3B A;  3DFR A;  3KFY A;  4X5I A;  3TQ9 A;  1DYR A;  1DF7 A;  4KD7 A;  5U27 A;  3DG8 A;  2CD2 A;  3EIG A;  4GH8 A;  2XW7 A;  3SRW X;  3Q1H A;  3HJ3 A;  3SRS X;  4PSY A;  4XEC X;  1DG7 A;  3F8Z A;  3FL8 A;  1LUD A;  4QLG A;  5FDA A;  4Q67 A;  5HVB A;  3IA5 A;  1RX3 A;  3NZ6 X;  5JG0 X;  1RA1 A;  4CD2 A;  3NXY A;  4M6K A;  3S9U A;  3VCO A;  3FRA X;  5HI6 A;  2HM9 A;  2BLB A;  4XRB A;  3FS6 A;  4QI9 A;  3QG2 A;  3SQY X;  2GD9 A;  4EJ1 A;  1IA1 A;  4KM2 A;  7DFR A;  2QK8 A;  1MVT A;  1RX6 A;  3KJR A;  3NZA X;  3NZD A;  2D0K A;  4I1N A;  3FQ0 A;  5HF0 X;  4OSG A;  1DG8 A;  1RG7 A;  3FQF A;  3UM6 A;  4KL9 A;  4I13 A;  3D84 X;  1RX4 A;  1KMV A;  1DRA A;  4KJL A;  3JW3 A;  4KY4 A;  4DPD A;  4M6L A;  4X5J A;  3DRC A;  3IA4 A;  3I8A X;  4G95 A;  3F0U X;  5ECC A;  3QFX A;  4EIZ A;  3JSU A;  3OAF A;  1AOE A;  1RX5 A;  4KJJ A;  2OBC A;  2L28 A;  3L3R A;  1S3U A;  3F8Y A;  3QLR A;  4XT6 A;  3IRM A;  4IXF X;  4ELB A;  1DR6 A;  3SRR X;  5CC9 A;  2D5N A;  4H95 A;  3D80 A;  1RX7 A;  2KGK A;  4NX6 A;  5DXV A;  1DDS A;  3S7A A;  4Q0E A;  4G3M A;  3SGY A;  4KEB A;  1J3K A;  4X5G A;  1DIS A;  5EAJ A;  4Q6A A;  3HBB A;  3DL6 A;  3QGT A;  3FRD X;  3NTZ A;  1PD9 A;  4M7V A;  1U72 A;  4X5F A;  4QLE A;  2BL9 A;  1IA2 A;  1DRF A;  3K47 A;  4ELF A;  3CD2 A;  3FRB X;  2ITH A;  2CIG A;  4LEK X;  4HOG A;  1E26 A;  4PTJ A;  1D1G A;  3KY8 A;  3M08 A;  5E8Q A;  2DRC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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