1DDSA

Molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Escherichia coli
publication title The effect of denaturants on protein structure.
pubmed rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 41
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1995-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1ddsA00
1TDRA 2KGKA 4G8ZX 3NZBX 1DRBA 1VJ3A 1DG5A 3M08A 4M6LA 4EIGA 5JA3A 3F0XX 4XT8A 3F8ZA 2JYBA 3NTZA 3Q1HA 3QYLA 3NRRA 4ELEA 3NZDA 7DFRA 3IRMA 2W3WA 1CZ3A 4KEBA 3QFXA 1DR7A 1LY3A 1MVSA 4XRBA 3FREX 1RF7A 3DRCA 3DGAA 3RG9A 3NZ9X 3OAFA 4KAKA 1BOZA 4X5HA 1DLSA 5DXVA 2OBCA 4P68A 4KD7A 2BLBA 3SAIA 4M7UA 4QJZD 3CSEA 3M09A 1U72A 4I1NA 3ZPCA 3QG2A 1S3WA 4TU5X 1DYIA 4Q0EA 4PTHA 3EEJA 1DF7A 5HF0X 4PDJA 4FGHA 4NX6A 3DATA 3EIGA 4I13A 4XECX 4G3MA 3NXRA 3NU0A 3SH2A 3F0VX 1M7AA 6DFRA 4H96A 3ROAA 4KL9A 2INQA 3IX9A 3FS6A 3CD2A 1KMSA 2XW7A 3JW5A 4OR7A 3NZAX 2ANOA 3SGYA 3NXXA 3GYFA 1DIUA 1PDBA 2D0KA 3FYVX 4KLXA 4LAHX 1DYHA 4HOGA 4P3RA 2H2QA 1JOMA 3R33A 4KJLA 1RX8A 8DFRA 5U26A 2L28A 3F0UX 4DP3A 3CL9A 3S3VA 3KFYA 3QLXA 4PSYA 3SA2A 2BLCA 3FQZA 3SA1A 2ANQA 3DG8A 5HVBA 2CIGA 1OHJA 4XT7A 3NZCX 1RX2A 3TQ8A 5HQYA 4H97A 1DHIA 1RA1A 4HA7A 3I8AX 2LF1A 3HBBA 4EJ1A 4KM0A 1DHFA 3K45A 3TD8A 3GI2A 3QL0A 2BL9A 1DR5A 2DHFA 4XT5A 1IA2A 5E8QA 1PD8A 1U70A 1RB3A 4QLFA 2W3MA 4X5FA 4ELGA 4IXFX 3JSUA 3K47A 4PSTA 1DR2A 5U27A 2GD9A 3SR5X 2ITHA 4LEKX 1J3IA 2CD2A 3SRWX 1JUVA 3GHVA 3VCOA 4M2XA 1M79A 4XT4A 1RX7A 1LY4A 1J3JA 3QYOA 1S3YA 1DRAA 1RA2A 3NZ6X 4KBNA 4QJCA 3FY9X 1RA8A 2O7PA 1DLRA 1RX6A 3KJRA 2W3VA 4LAGX 1DG8A 3FRAX 4HOFA 2W3BA 1RX1A 3EEMA 2FZJA 3OCHA 5HPBA 3CLBA 1RX4A 4ECKA 1PD9A 5ECXA 1HFRA 4NX7A 4FGGA 3FYWX 4KJJA 1DYRA 1ZDRA 1J3KA 4X5JA 5HVEA 1RX3A 1RH3A 3SRQX 4KY4A 1AOEA 4QI9A 1AO8A 5HI6A 1DHJA 3JTWA 5HUIA 4DFRA 3FQFA 3IROA 4EILA 4QLEA 3E0BA 4KJKA 3HJ3A 3QL3A 3F91A 5JG0X 4LAEX 3F0QX 3FQVA 4PTJA 3FRBX 3K74A 3QLSA 3SRSX 5HT5A 4X5GA 4G95A 3QGTA 1RX9A 4ELHA 4P66A 1D1GA 3JVXA 3IA5A 3D84X 2AZNA 3FY8X 5CCCA 3JWMA 2D5NA 3QLRA 3F8YA 1YHOA 1M78A 2FZHA 1DR4A 2G6VA 1DYJA 3LG4A 3FQOA 1DR6A 3QLZA 4IXED 4QLGA 3FRDX 1RA3A 3ZPGA 3K2HA 3DFRA 4DPHA 4KNEA 3DL6A 3INVA 1SEJA 4KYAA 3JWFA 1S3VA 4H95A 2W9TA 4Q0DA 3UM5A 1IA1A 1RB2A 2B3ZA 5ECCA 3IRNA 4ELFA 3N0HA 3QLYA 5HT4A 2FZIA 3NXYA 1AI9A 1IA3A 4Q6AA 1DDRA 3IA4A 1RE7A 1RX5A 4EIZA 4Q67A 4KM2A 1RA9A 4X5IA 1DG7A 1DRHA 3EX8A 2W9GA 2DRCA 1MVTA 3UM6A 5HSRA 4OSGA 4XT6A 1S3UA 3DAUA 2BLAA 3KGYA 5HQZA 3FQ0A 1U71A 4DPDA 3QLWA 4M6KA 2QK8A 1DR1A 4H98A 3FRFX 4IXGX 4P3QA 1DISA 1VDRA 4M6JA 3F0BX 3TQAA 3GHWA 1LUDA 1DDSA 1RG7A 1QZFA 1OHKA 2HQPA 3JWCA 2OIPA 3FL9A 4RGCA 1KLKA 4HOEA 2C2TA 1RD7A 4KFJA 1HFPA 3KY8A 3S9UA 3SRUX 1KMVA 5EAJA 2P4GA 4M7VA 1DREA 3F0SX 2ZZAA 4QHVA 3FQCA 5CC9A 3JW3A 3NXOA 3NXTA 4CD2A 1E26A 1CD2A 3L3RA 3TQ9A 2W9HA 3I3RA 2C2SA 3DL5A 1RC4A 5FDAA 3D80A 4FHBA 5HSUA 3S7AA 1DR3A 2W3AA 1HFQA 5DFRA 3JWKA 4GH8A 3UM8A 1IA4A 3EELA 1BZFA 3NXVA 4KY8A 1DAJA 4DDRA 3KJSA 2W9SA 4XE6X 2HXVA 3GHCA 5HF2X 4PSSA 1DRFA 4ELBA 2HM9A 3FL8A 3SRRX 1JOLA 4HA9A 3RO9A 3TQBA 3SQYX 3EEKA
chains in the Genus database with same CATH superfamily
1TDRA 2KGKA 4G8ZX 3NZBX 1DRBA 1VJ3A 1DG5A 3M08A 4M6LA 4EIGA 5JA3A 3F0XX 4XT8A 3F8ZA 2JYBA 3NTZA 3Q1HA 3QYLA 3NRRA 4ELEA 3NZDA 7DFRA 3IRMA 2W3WA 1CZ3A 4KEBA 3QFXA 1DR7A 1LY3A 1MVSA 4XRBA 3FREX 1RF7A 3DRCA 3DGAA 3RG9A 3NZ9X 3OAFA 4KAKA 1BOZA 4X5HA 1DLSA 5DXVA 2OBCA 4P68A 4KD7A 2BLBA 3SAIA 4M7UA 4QJZD 3CSEA 3M09A 1U72A 4I1NA 3ZPCA 3QG2A 1S3WA 4TU5X 1DYIA 4Q0EA 4PTHA 3EEJA 1DF7A 5HF0X 4PDJA 4FGHA 4NX6A 3DATA 3EIGA 4I13A 4XECX 4G3MA 3NXRA 3NU0A 3SH2A 3F0VX 1M7AA 6DFRA 4H96A 3ROAA 4KL9A 2INQA 3IX9A 3FS6A 3CD2A 1KMSA 2XW7A 3JW5A 4OR7A 3NZAX 2ANOA 3SGYA 3NXXA 3GYFA 1DIUA 1PDBA 2D0KA 3FYVX 4KLXA 4LAHX 1DYHA 4HOGA 4P3RA 2H2QA 1JOMA 3R33A 4KJLA 1RX8A 8DFRA 5U26A 2L28A 3F0UX 4DP3A 3CL9A 3S3VA 3KFYA 3QLXA 4PSYA 3SA2A 2BLCA 3FQZA 3SA1A 2ANQA 3DG8A 5HVBA 2CIGA 1OHJA 4XT7A 3NZCX 1RX2A 3TQ8A 5HQYA 4H97A 1DHIA 1RA1A 4HA7A 3I8AX 2LF1A 3HBBA 4EJ1A 4KM0A 1DHFA 3K45A 3TD8A 3GI2A 3QL0A 2BL9A 1DR5A 2DHFA 4XT5A 1IA2A 5E8QA 1PD8A 1U70A 1RB3A 4QLFA 2W3MA 4X5FA 4ELGA 4IXFX 3JSUA 3K47A 4PSTA 1DR2A 5U27A 2GD9A 3SR5X 2ITHA 4LEKX 1J3IA 2CD2A 3SRWX 1JUVA 3GHVA 3VCOA 4M2XA 1M79A 4XT4A 1RX7A 1LY4A 1J3JA 3QYOA 1S3YA 1DRAA 1RA2A 3NZ6X 4KBNA 4QJCA 3FY9X 1RA8A 2O7PA 1DLRA 1RX6A 3KJRA 2W3VA 4LAGX 1DG8A 3FRAX 4HOFA 2W3BA 1RX1A 3EEMA 2FZJA 3OCHA 5HPBA 3CLBA 1RX4A 4ECKA 1PD9A 5ECXA 1HFRA 4NX7A 4FGGA 3FYWX 4KJJA 1DYRA 1ZDRA 1J3KA 4X5JA 5HVEA 1RX3A 1RH3A 3SRQX 4KY4A 1AOEA 4QI9A 1AO8A 5HI6A 1DHJA 3JTWA 5HUIA 4DFRA 3FQFA 3IROA 4EILA 4QLEA 3E0BA 4KJKA 3HJ3A 3QL3A 3F91A 5JG0X 4LAEX 3F0QX 3FQVA 4PTJA 3FRBX 3K74A 3QLSA 3SRSX 5HT5A 4X5GA 4G95A 3QGTA 1RX9A 4ELHA 4P66A 1D1GA 3JVXA 3IA5A 3D84X 2AZNA 3FY8X 5CCCA 3JWMA 2D5NA 3QLRA 3F8YA 1YHOA 1M78A 2FZHA 1DR4A 2G6VA 1DYJA 3LG4A 3FQOA 1DR6A 3QLZA 4IXED 4QLGA 3FRDX 1RA3A 3ZPGA 3K2HA 3DFRA 4DPHA 4KNEA 3DL6A 3INVA 1SEJA 4KYAA 3JWFA 1S3VA 4H95A 2W9TA 4Q0DA 3UM5A 1IA1A 1RB2A 2B3ZA 5ECCA 3IRNA 4ELFA 3N0HA 3QLYA 5HT4A 2FZIA 3NXYA 1AI9A 1IA3A 4Q6AA 1DDRA 3IA4A 1RE7A 1RX5A 4EIZA 4Q67A 4KM2A 1RA9A 4X5IA 1DG7A 1DRHA 3EX8A 2W9GA 2DRCA 1MVTA 3UM6A 5HSRA 4OSGA 4XT6A 1S3UA 3DAUA 2BLAA 3KGYA 5HQZA 3FQ0A 1U71A 4DPDA 3QLWA 4M6KA 2QK8A 1DR1A 4H98A 3FRFX 4IXGX 4P3QA 1DISA 1VDRA 4M6JA 3F0BX 3TQAA 3GHWA 1LUDA 1DDSA 1RG7A 1QZFA 1OHKA 2HQPA 3JWCA 2OIPA 3FL9A 4RGCA 1KLKA 4HOEA 2C2TA 1RD7A 4KFJA 1HFPA 3KY8A 3S9UA 3SRUX 1KMVA 5EAJA 2P4GA 4M7VA 1DREA 3F0SX 2ZZAA 4QHVA 3FQCA 5CC9A 3JW3A 3NXOA 3NXTA 4CD2A 1E26A 1CD2A 3L3RA 3TQ9A 2W9HA 3I3RA 2C2SA 3DL5A 1RC4A 5FDAA 3D80A 4FHBA 5HSUA 3S7AA 1DR3A 2W3AA 1HFQA 5DFRA 3JWKA 4GH8A 3UM8A 1IA4A 3EELA 1BZFA 3NXVA 4KY8A 1DAJA 4DDRA 3KJSA 2W9SA 4XE6X 2HXVA 3GHCA 5HF2X 4PSSA 1DRFA 4ELBA 2HM9A 3FL8A 3SRRX 1JOLA 4HA9A 3RO9A 3TQBA 3SQYX 3EEKA
chains in the Genus database with same CATH topology
1TDRA 2KGKA 4G8ZX 3NZBX 1DRBA 1VJ3A 1DG5A 3M08A 4M6LA 4EIGA 5JA3A 3F0XX 4XT8A 3F8ZA 2JYBA 3NTZA 3Q1HA 3QYLA 3NRRA 4ELEA 3NZDA 7DFRA 3IRMA 2W3WA 1CZ3A 4KEBA 3QFXA 1DR7A 1LY3A 1MVSA 4XRBA 3FREX 1RF7A 3DRCA 3DGAA 3RG9A 3NZ9X 3OAFA 4KAKA 1BOZA 4X5HA 1DLSA 5DXVA 2OBCA 4P68A 4KD7A 2BLBA 3SAIA 4M7UA 4QJZD 3CSEA 3M09A 1U72A 4I1NA 3ZPCA 3QG2A 1S3WA 4TU5X 1DYIA 4Q0EA 4PTHA 3EEJA 1DF7A 5HF0X 4PDJA 4FGHA 4NX6A 3DATA 3EIGA 4I13A 4XECX 4G3MA 3NXRA 3NU0A 3SH2A 3F0VX 1M7AA 6DFRA 4H96A 3ROAA 4KL9A 2INQA 3IX9A 3FS6A 3CD2A 1KMSA 2XW7A 3JW5A 4OR7A 3NZAX 2ANOA 3SGYA 3NXXA 3GYFA 1DIUA 1PDBA 2D0KA 3FYVX 4KLXA 4LAHX 1DYHA 4HOGA 4P3RA 2H2QA 1JOMA 3R33A 4KJLA 1RX8A 8DFRA 5U26A 2L28A 3F0UX 4DP3A 3CL9A 3S3VA 3KFYA 3QLXA 4PSYA 3SA2A 2BLCA 3FQZA 3SA1A 2ANQA 3DG8A 5HVBA 2CIGA 1OHJA 4XT7A 3NZCX 1RX2A 3TQ8A 5HQYA 4H97A 1DHIA 1RA1A 4HA7A 3I8AX 2LF1A 3HBBA 4EJ1A 4KM0A 1DHFA 3K45A 3TD8A 3GI2A 3QL0A 2BL9A 1DR5A 2DHFA 4XT5A 1IA2A 5E8QA 1PD8A 1U70A 1RB3A 4QLFA 2W3MA 4X5FA 4ELGA 4IXFX 3JSUA 3K47A 4PSTA 1DR2A 5U27A 2GD9A 3SR5X 2ITHA 4LEKX 1J3IA 2CD2A 3SRWX 1JUVA 3GHVA 3VCOA 4M2XA 1M79A 4XT4A 1RX7A 1LY4A 1J3JA 3QYOA 1S3YA 1DRAA 1RA2A 3NZ6X 4KBNA 4QJCA 3FY9X 1RA8A 2O7PA 1DLRA 1RX6A 3KJRA 2W3VA 4LAGX 1DG8A 3FRAX 4HOFA 2W3BA 1RX1A 3EEMA 2FZJA 3OCHA 5HPBA 3CLBA 1RX4A 4ECKA 1PD9A 5ECXA 1HFRA 4NX7A 4FGGA 3FYWX 4KJJA 1DYRA 1ZDRA 1J3KA 4X5JA 5HVEA 1RX3A 1RH3A 3SRQX 4KY4A 1AOEA 4QI9A 1AO8A 5HI6A 1DHJA 3JTWA 5HUIA 4DFRA 3FQFA 3IROA 4EILA 4QLEA 3E0BA 4KJKA 3HJ3A 3QL3A 3F91A 5JG0X 4LAEX 3F0QX 3FQVA 4PTJA 3FRBX 3K74A 3QLSA 3SRSX 5HT5A 4X5GA 4G95A 3QGTA 1RX9A 4ELHA 4P66A 1D1GA 3JVXA 3IA5A 3D84X 2AZNA 3FY8X 5CCCA 3JWMA 2D5NA 3QLRA 3F8YA 1YHOA 1M78A 2FZHA 1DR4A 2G6VA 1DYJA 3LG4A 3FQOA 1DR6A 3QLZA 4IXED 4QLGA 3FRDX 1RA3A 3ZPGA 3K2HA 3DFRA 4DPHA 4KNEA 3DL6A 3INVA 1SEJA 4KYAA 3JWFA 1S3VA 4H95A 2W9TA 4Q0DA 3UM5A 1IA1A 1RB2A 2B3ZA 5ECCA 3IRNA 4ELFA 3N0HA 3QLYA 5HT4A 2FZIA 3NXYA 1AI9A 1IA3A 4Q6AA 1DDRA 3IA4A 1RE7A 1RX5A 4EIZA 4Q67A 4KM2A 1RA9A 4X5IA 1DG7A 1DRHA 3EX8A 2W9GA 2DRCA 1MVTA 3UM6A 5HSRA 4OSGA 4XT6A 1S3UA 3DAUA 2BLAA 3KGYA 5HQZA 3FQ0A 1U71A 4DPDA 3QLWA 4M6KA 2QK8A 1DR1A 4H98A 3FRFX 4IXGX 4P3QA 1DISA 1VDRA 4M6JA 3F0BX 3TQAA 3GHWA 1LUDA 1DDSA 1RG7A 1QZFA 1OHKA 2HQPA 3JWCA 2OIPA 3FL9A 4RGCA 1KLKA 4HOEA 2C2TA 1RD7A 4KFJA 1HFPA 3KY8A 3S9UA 3SRUX 1KMVA 5EAJA 2P4GA 4M7VA 1DREA 3F0SX 2ZZAA 4QHVA 3FQCA 5CC9A 3JW3A 3NXOA 3NXTA 4CD2A 1E26A 1CD2A 3L3RA 3TQ9A 2W9HA 3I3RA 2C2SA 3DL5A 1RC4A 5FDAA 3D80A 4FHBA 5HSUA 3S7AA 1DR3A 2W3AA 1HFQA 5DFRA 3JWKA 4GH8A 3UM8A 1IA4A 3EELA 1BZFA 3NXVA 4KY8A 1DAJA 4DDRA 3KJSA 2W9SA 4XE6X 2HXVA 3GHCA 5HF2X 4PSSA 1DRFA 4ELBA 2HM9A 3FL8A 3SRRX 1JOLA 4HA9A 3RO9A 3TQBA 3SQYX 3EEKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TDR A;  2KGK A;  4G8Z X;  3NZB X;  1DRB A;  1VJ3 A;  1DG5 A;  3M08 A;  4M6L A;  4EIG A;  5JA3 A;  3F0X X;  4XT8 A;  3F8Z A;  2JYB A;  3NTZ A;  3Q1H A;  3QYL A;  3NRR A;  4ELE A;  3NZD A;  7DFR A;  3IRM A;  2W3W A;  1CZ3 A;  4KEB A;  3QFX A;  1DR7 A;  1LY3 A;  1MVS A;  4XRB A;  3FRE X;  1RF7 A;  3DRC A;  3DGA A;  3RG9 A;  3NZ9 X;  3OAF A;  4KAK A;  1BOZ A;  4X5H A;  1DLS A;  5DXV A;  2OBC A;  4P68 A;  4KD7 A;  2BLB A;  3SAI A;  4M7U A;  4QJZ D;  3CSE A;  3M09 A;  1U72 A;  4I1N A;  3ZPC A;  3QG2 A;  1S3W A;  4TU5 X;  1DYI A;  4Q0E A;  4PTH A;  3EEJ A;  1DF7 A;  5HF0 X;  4PDJ A;  4FGH A;  4NX6 A;  3DAT A;  3EIG A;  4I13 A;  4XEC X;  4G3M A;  3NXR A;  3NU0 A;  3SH2 A;  3F0V X;  1M7A A;  6DFR A;  4H96 A;  3ROA A;  4KL9 A;  2INQ A;  3IX9 A;  3FS6 A;  3CD2 A;  1KMS A;  2XW7 A;  3JW5 A;  4OR7 A;  3NZA X;  2ANO A;  3SGY A;  3NXX A;  3GYF A;  1DIU A;  1PDB A;  2D0K A;  3FYV X;  4KLX A;  4LAH X;  1DYH A;  4HOG A;  4P3R A;  2H2Q A;  1JOM A;  3R33 A;  4KJL A;  1RX8 A;  8DFR A;  5U26 A;  2L28 A;  3F0U X;  4DP3 A;  3CL9 A;  3S3V A;  3KFY A;  3QLX A;  4PSY A;  3SA2 A;  2BLC A;  3FQZ A;  3SA1 A;  2ANQ A;  3DG8 A;  5HVB A;  2CIG A;  1OHJ A;  4XT7 A;  3NZC X;  1RX2 A;  3TQ8 A;  5HQY A;  4H97 A;  1DHI A;  1RA1 A;  4HA7 A;  3I8A X;  2LF1 A;  3HBB A;  4EJ1 A;  4KM0 A;  1DHF A;  3K45 A;  3TD8 A;  3GI2 A;  3QL0 A;  2BL9 A;  1DR5 A;  2DHF A;  4XT5 A;  1IA2 A;  5E8Q A;  1PD8 A;  1U70 A;  1RB3 A;  4QLF A;  2W3M A;  4X5F A;  4ELG A;  4IXF X;  3JSU A;  3K47 A;  4PST A;  1DR2 A;  5U27 A;  2GD9 A;  3SR5 X;  2ITH A;  4LEK X;  1J3I A;  2CD2 A;  3SRW X;  1JUV A;  3GHV A;  3VCO A;  4M2X A;  1M79 A;  4XT4 A;  1RX7 A;  1LY4 A;  1J3J A;  3QYO A;  1S3Y A;  1DRA A;  1RA2 A;  3NZ6 X;  4KBN A;  4QJC A;  3FY9 X;  1RA8 A;  2O7P A;  1DLR A;  1RX6 A;  3KJR A;  2W3V A;  4LAG X;  1DG8 A;  3FRA X;  4HOF A;  2W3B A;  1RX1 A;  3EEM A;  2FZJ A;  3OCH A;  5HPB A;  3CLB A;  1RX4 A;  4ECK A;  1PD9 A;  5ECX A;  1HFR A;  4NX7 A;  4FGG A;  3FYW X;  4KJJ A;  1DYR A;  1ZDR A;  1J3K A;  4X5J A;  5HVE A;  1RX3 A;  1RH3 A;  3SRQ X;  4KY4 A;  1AOE A;  4QI9 A;  1AO8 A;  5HI6 A;  1DHJ A;  3JTW A;  5HUI A;  4DFR A;  3FQF A;  3IRO A;  4EIL A;  4QLE A;  3E0B A;  4KJK A;  3HJ3 A;  3QL3 A;  3F91 A;  5JG0 X;  4LAE X;  3F0Q X;  3FQV A;  4PTJ A;  3FRB X;  3K74 A;  3QLS A;  3SRS X;  5HT5 A;  4X5G A;  4G95 A;  3QGT A;  1RX9 A;  4ELH A;  4P66 A;  1D1G A;  3JVX A;  3IA5 A;  3D84 X;  2AZN A;  3FY8 X;  5CCC A;  3JWM A;  2D5N A;  3QLR A;  3F8Y A;  1YHO A;  1M78 A;  2FZH A;  1DR4 A;  2G6V A;  1DYJ A;  3LG4 A;  3FQO A;  1DR6 A;  3QLZ A;  4IXE D;  4QLG A;  3FRD X;  1RA3 A;  3ZPG A;  3K2H A;  3DFR A;  4DPH A;  4KNE A;  3DL6 A;  3INV A;  1SEJ A;  4KYA A;  3JWF A;  1S3V A;  4H95 A;  2W9T A;  4Q0D A;  3UM5 A;  1IA1 A;  1RB2 A;  2B3Z A;  5ECC A;  3IRN A;  4ELF A;  3N0H A;  3QLY A;  5HT4 A;  2FZI A;  3NXY A;  1AI9 A;  1IA3 A;  4Q6A A;  1DDR A;  3IA4 A;  1RE7 A;  1RX5 A;  4EIZ A;  4Q67 A;  4KM2 A;  1RA9 A;  4X5I A;  1DG7 A;  1DRH A;  3EX8 A;  2W9G A;  2DRC A;  1MVT A;  3UM6 A;  5HSR A;  4OSG A;  4XT6 A;  1S3U A;  3DAU A;  2BLA A;  3KGY A;  5HQZ A;  3FQ0 A;  1U71 A;  4DPD A;  3QLW A;  4M6K A;  2QK8 A;  1DR1 A;  4H98 A;  3FRF X;  4IXG X;  4P3Q A;  1DIS A;  1VDR A;  4M6J A;  3F0B X;  3TQA A;  3GHW A;  1LUD A;  1DDS A;  1RG7 A;  1QZF A;  1OHK A;  2HQP A;  3JWC A;  2OIP A;  3FL9 A;  4RGC A;  1KLK A;  4HOE A;  2C2T A;  1RD7 A;  4KFJ A;  1HFP A;  3KY8 A;  3S9U A;  3SRU X;  1KMV A;  5EAJ A;  2P4G A;  4M7V A;  1DRE A;  3F0S X;  2ZZA A;  4QHV A;  3FQC A;  5CC9 A;  3JW3 A;  3NXO A;  3NXT A;  4CD2 A;  1E26 A;  1CD2 A;  3L3R A;  3TQ9 A;  2W9H A;  3I3R A;  2C2S A;  3DL5 A;  1RC4 A;  5FDA A;  3D80 A;  4FHB A;  5HSU A;  3S7A A;  1DR3 A;  2W3A A;  1HFQ A;  5DFR A;  3JWK A;  4GH8 A;  3UM8 A;  1IA4 A;  3EEL A;  1BZF A;  3NXV A;  4KY8 A;  1DAJ A;  4DDR A;  3KJS A;  2W9S A;  4XE6 X;  2HXV A;  3GHC A;  5HF2 X;  4PSS A;  1DRF A;  4ELB A;  2HM9 A;  3FL8 A;  3SRR X;  1JOL A;  4HA9 A;  3RO9 A;  3TQB A;  3SQY X;  3EEK A; 
#chains in the Genus database with same CATH topology
 1TDR A;  2KGK A;  4G8Z X;  3NZB X;  1DRB A;  1VJ3 A;  1DG5 A;  3M08 A;  4M6L A;  4EIG A;  5JA3 A;  3F0X X;  4XT8 A;  3F8Z A;  2JYB A;  3NTZ A;  3Q1H A;  3QYL A;  3NRR A;  4ELE A;  3NZD A;  7DFR A;  3IRM A;  2W3W A;  1CZ3 A;  4KEB A;  3QFX A;  1DR7 A;  1LY3 A;  1MVS A;  4XRB A;  3FRE X;  1RF7 A;  3DRC A;  3DGA A;  3RG9 A;  3NZ9 X;  3OAF A;  4KAK A;  1BOZ A;  4X5H A;  1DLS A;  5DXV A;  2OBC A;  4P68 A;  4KD7 A;  2BLB A;  3SAI A;  4M7U A;  4QJZ D;  3CSE A;  3M09 A;  1U72 A;  4I1N A;  3ZPC A;  3QG2 A;  1S3W A;  4TU5 X;  1DYI A;  4Q0E A;  4PTH A;  3EEJ A;  1DF7 A;  5HF0 X;  4PDJ A;  4FGH A;  4NX6 A;  3DAT A;  3EIG A;  4I13 A;  4XEC X;  4G3M A;  3NXR A;  3NU0 A;  3SH2 A;  3F0V X;  1M7A A;  6DFR A;  4H96 A;  3ROA A;  4KL9 A;  2INQ A;  3IX9 A;  3FS6 A;  3CD2 A;  1KMS A;  2XW7 A;  3JW5 A;  4OR7 A;  3NZA X;  2ANO A;  3SGY A;  3NXX A;  3GYF A;  1DIU A;  1PDB A;  2D0K A;  3FYV X;  4KLX A;  4LAH X;  1DYH A;  4HOG A;  4P3R A;  2H2Q A;  1JOM A;  3R33 A;  4KJL A;  1RX8 A;  8DFR A;  5U26 A;  2L28 A;  3F0U X;  4DP3 A;  3CL9 A;  3S3V A;  3KFY A;  3QLX A;  4PSY A;  3SA2 A;  2BLC A;  3FQZ A;  3SA1 A;  2ANQ A;  3DG8 A;  5HVB A;  2CIG A;  1OHJ A;  4XT7 A;  3NZC X;  1RX2 A;  3TQ8 A;  5HQY A;  4H97 A;  1DHI A;  1RA1 A;  4HA7 A;  3I8A X;  2LF1 A;  3HBB A;  4EJ1 A;  4KM0 A;  1DHF A;  3K45 A;  3TD8 A;  3GI2 A;  3QL0 A;  2BL9 A;  1DR5 A;  2DHF A;  4XT5 A;  1IA2 A;  5E8Q A;  1PD8 A;  1U70 A;  1RB3 A;  4QLF A;  2W3M A;  4X5F A;  4ELG A;  4IXF X;  3JSU A;  3K47 A;  4PST A;  1DR2 A;  5U27 A;  2GD9 A;  3SR5 X;  2ITH A;  4LEK X;  1J3I A;  2CD2 A;  3SRW X;  1JUV A;  3GHV A;  3VCO A;  4M2X A;  1M79 A;  4XT4 A;  1RX7 A;  1LY4 A;  1J3J A;  3QYO A;  1S3Y A;  1DRA A;  1RA2 A;  3NZ6 X;  4KBN A;  4QJC A;  3FY9 X;  1RA8 A;  2O7P A;  1DLR A;  1RX6 A;  3KJR A;  2W3V A;  4LAG X;  1DG8 A;  3FRA X;  4HOF A;  2W3B A;  1RX1 A;  3EEM A;  2FZJ A;  3OCH A;  5HPB A;  3CLB A;  1RX4 A;  4ECK A;  1PD9 A;  5ECX A;  1HFR A;  4NX7 A;  4FGG A;  3FYW X;  4KJJ A;  1DYR A;  1ZDR A;  1J3K A;  4X5J A;  5HVE A;  1RX3 A;  1RH3 A;  3SRQ X;  4KY4 A;  1AOE A;  4QI9 A;  1AO8 A;  5HI6 A;  1DHJ A;  3JTW A;  5HUI A;  4DFR A;  3FQF A;  3IRO A;  4EIL A;  4QLE A;  3E0B A;  4KJK A;  3HJ3 A;  3QL3 A;  3F91 A;  5JG0 X;  4LAE X;  3F0Q X;  3FQV A;  4PTJ A;  3FRB X;  3K74 A;  3QLS A;  3SRS X;  5HT5 A;  4X5G A;  4G95 A;  3QGT A;  1RX9 A;  4ELH A;  4P66 A;  1D1G A;  3JVX A;  3IA5 A;  3D84 X;  2AZN A;  3FY8 X;  5CCC A;  3JWM A;  2D5N A;  3QLR A;  3F8Y A;  1YHO A;  1M78 A;  2FZH A;  1DR4 A;  2G6V A;  1DYJ A;  3LG4 A;  3FQO A;  1DR6 A;  3QLZ A;  4IXE D;  4QLG A;  3FRD X;  1RA3 A;  3ZPG A;  3K2H A;  3DFR A;  4DPH A;  4KNE A;  3DL6 A;  3INV A;  1SEJ A;  4KYA A;  3JWF A;  1S3V A;  4H95 A;  2W9T A;  4Q0D A;  3UM5 A;  1IA1 A;  1RB2 A;  2B3Z A;  5ECC A;  3IRN A;  4ELF A;  3N0H A;  3QLY A;  5HT4 A;  2FZI A;  3NXY A;  1AI9 A;  1IA3 A;  4Q6A A;  1DDR A;  3IA4 A;  1RE7 A;  1RX5 A;  4EIZ A;  4Q67 A;  4KM2 A;  1RA9 A;  4X5I A;  1DG7 A;  1DRH A;  3EX8 A;  2W9G A;  2DRC A;  1MVT A;  3UM6 A;  5HSR A;  4OSG A;  4XT6 A;  1S3U A;  3DAU A;  2BLA A;  3KGY A;  5HQZ A;  3FQ0 A;  1U71 A;  4DPD A;  3QLW A;  4M6K A;  2QK8 A;  1DR1 A;  4H98 A;  3FRF X;  4IXG X;  4P3Q A;  1DIS A;  1VDR A;  4M6J A;  3F0B X;  3TQA A;  3GHW A;  1LUD A;  1DDS A;  1RG7 A;  1QZF A;  1OHK A;  2HQP A;  3JWC A;  2OIP A;  3FL9 A;  4RGC A;  1KLK A;  4HOE A;  2C2T A;  1RD7 A;  4KFJ A;  1HFP A;  3KY8 A;  3S9U A;  3SRU X;  1KMV A;  5EAJ A;  2P4G A;  4M7V A;  1DRE A;  3F0S X;  2ZZA A;  4QHV A;  3FQC A;  5CC9 A;  3JW3 A;  3NXO A;  3NXT A;  4CD2 A;  1E26 A;  1CD2 A;  3L3R A;  3TQ9 A;  2W9H A;  3I3R A;  2C2S A;  3DL5 A;  1RC4 A;  5FDA A;  3D80 A;  4FHB A;  5HSU A;  3S7A A;  1DR3 A;  2W3A A;  1HFQ A;  5DFR A;  3JWK A;  4GH8 A;  3UM8 A;  1IA4 A;  3EEL A;  1BZF A;  3NXV A;  4KY8 A;  1DAJ A;  4DDR A;  3KJS A;  2W9S A;  4XE6 X;  2HXV A;  3GHC A;  5HF2 X;  4PSS A;  1DRF A;  4ELB A;  2HM9 A;  3FL8 A;  3SRR X;  1JOL A;  4HA9 A;  3RO9 A;  3TQB A;  3SQY X;  3EEK A; 
#chains in the Genus database with same CATH homology
 1TDR A;  2KGK A;  4G8Z X;  3NZB X;  1DRB A;  1VJ3 A;  1DG5 A;  3M08 A;  4M6L A;  4EIG A;  5JA3 A;  3F0X X;  4XT8 A;  3F8Z A;  2JYB A;  3NTZ A;  3Q1H A;  3QYL A;  3NRR A;  4ELE A;  3NZD A;  7DFR A;  3IRM A;  2W3W A;  1CZ3 A;  4KEB A;  3QFX A;  1DR7 A;  1LY3 A;  1MVS A;  4XRB A;  3FRE X;  1RF7 A;  3DRC A;  3DGA A;  3RG9 A;  3NZ9 X;  3OAF A;  4KAK A;  1BOZ A;  4X5H A;  1DLS A;  5DXV A;  2OBC A;  4P68 A;  4KD7 A;  2BLB A;  3SAI A;  4M7U A;  4QJZ D;  3CSE A;  3M09 A;  1U72 A;  4I1N A;  3ZPC A;  3QG2 A;  1S3W A;  4TU5 X;  1DYI A;  4Q0E A;  4PTH A;  3EEJ A;  1DF7 A;  5HF0 X;  4PDJ A;  4FGH A;  4NX6 A;  3DAT A;  3EIG A;  4I13 A;  4XEC X;  4G3M A;  3NXR A;  3NU0 A;  3SH2 A;  3F0V X;  1M7A A;  6DFR A;  4H96 A;  3ROA A;  4KL9 A;  2INQ A;  3IX9 A;  3FS6 A;  3CD2 A;  1KMS A;  2XW7 A;  3JW5 A;  4OR7 A;  3NZA X;  2ANO A;  3SGY A;  3NXX A;  3GYF A;  1DIU A;  1PDB A;  2D0K A;  3FYV X;  4KLX A;  4LAH X;  1DYH A;  4HOG A;  4P3R A;  2H2Q A;  1JOM A;  3R33 A;  4KJL A;  1RX8 A;  8DFR A;  5U26 A;  2L28 A;  3F0U X;  4DP3 A;  3CL9 A;  3S3V A;  3KFY A;  3QLX A;  4PSY A;  3SA2 A;  2BLC A;  3FQZ A;  3SA1 A;  2ANQ A;  3DG8 A;  5HVB A;  2CIG A;  1OHJ A;  4XT7 A;  3NZC X;  1RX2 A;  3TQ8 A;  5HQY A;  4H97 A;  1DHI A;  1RA1 A;  4HA7 A;  3I8A X;  2LF1 A;  3HBB A;  4EJ1 A;  4KM0 A;  1DHF A;  3K45 A;  3TD8 A;  3GI2 A;  3QL0 A;  2BL9 A;  1DR5 A;  2DHF A;  4XT5 A;  1IA2 A;  5E8Q A;  1PD8 A;  1U70 A;  1RB3 A;  4QLF A;  2W3M A;  4X5F A;  4ELG A;  4IXF X;  3JSU A;  3K47 A;  4PST A;  1DR2 A;  5U27 A;  2GD9 A;  3SR5 X;  2ITH A;  4LEK X;  1J3I A;  2CD2 A;  3SRW X;  1JUV A;  3GHV A;  3VCO A;  4M2X A;  1M79 A;  4XT4 A;  1RX7 A;  1LY4 A;  1J3J A;  3QYO A;  1S3Y A;  1DRA A;  1RA2 A;  3NZ6 X;  4KBN A;  4QJC A;  3FY9 X;  1RA8 A;  2O7P A;  1DLR A;  1RX6 A;  3KJR A;  2W3V A;  4LAG X;  1DG8 A;  3FRA X;  4HOF A;  2W3B A;  1RX1 A;  3EEM A;  2FZJ A;  3OCH A;  5HPB A;  3CLB A;  1RX4 A;  4ECK A;  1PD9 A;  5ECX A;  1HFR A;  4NX7 A;  4FGG A;  3FYW X;  4KJJ A;  1DYR A;  1ZDR A;  1J3K A;  4X5J A;  5HVE A;  1RX3 A;  1RH3 A;  3SRQ X;  4KY4 A;  1AOE A;  4QI9 A;  1AO8 A;  5HI6 A;  1DHJ A;  3JTW A;  5HUI A;  4DFR A;  3FQF A;  3IRO A;  4EIL A;  4QLE A;  3E0B A;  4KJK A;  3HJ3 A;  3QL3 A;  3F91 A;  5JG0 X;  4LAE X;  3F0Q X;  3FQV A;  4PTJ A;  3FRB X;  3K74 A;  3QLS A;  3SRS X;  5HT5 A;  4X5G A;  4G95 A;  3QGT A;  1RX9 A;  4ELH A;  4P66 A;  1D1G A;  3JVX A;  3IA5 A;  3D84 X;  2AZN A;  3FY8 X;  5CCC A;  3JWM A;  2D5N A;  3QLR A;  3F8Y A;  1YHO A;  1M78 A;  2FZH A;  1DR4 A;  2G6V A;  1DYJ A;  3LG4 A;  3FQO A;  1DR6 A;  3QLZ A;  4IXE D;  4QLG A;  3FRD X;  1RA3 A;  3ZPG A;  3K2H A;  3DFR A;  4DPH A;  4KNE A;  3DL6 A;  3INV A;  1SEJ A;  4KYA A;  3JWF A;  1S3V A;  4H95 A;  2W9T A;  4Q0D A;  3UM5 A;  1IA1 A;  1RB2 A;  2B3Z A;  5ECC A;  3IRN A;  4ELF A;  3N0H A;  3QLY A;  5HT4 A;  2FZI A;  3NXY A;  1AI9 A;  1IA3 A;  4Q6A A;  1DDR A;  3IA4 A;  1RE7 A;  1RX5 A;  4EIZ A;  4Q67 A;  4KM2 A;  1RA9 A;  4X5I A;  1DG7 A;  1DRH A;  3EX8 A;  2W9G A;  2DRC A;  1MVT A;  3UM6 A;  5HSR A;  4OSG A;  4XT6 A;  1S3U A;  3DAU A;  2BLA A;  3KGY A;  5HQZ A;  3FQ0 A;  1U71 A;  4DPD A;  3QLW A;  4M6K A;  2QK8 A;  1DR1 A;  4H98 A;  3FRF X;  4IXG X;  4P3Q A;  1DIS A;  1VDR A;  4M6J A;  3F0B X;  3TQA A;  3GHW A;  1LUD A;  1DDS A;  1RG7 A;  1QZF A;  1OHK A;  2HQP A;  3JWC A;  2OIP A;  3FL9 A;  4RGC A;  1KLK A;  4HOE A;  2C2T A;  1RD7 A;  4KFJ A;  1HFP A;  3KY8 A;  3S9U A;  3SRU X;  1KMV A;  5EAJ A;  2P4G A;  4M7V A;  1DRE A;  3F0S X;  2ZZA A;  4QHV A;  3FQC A;  5CC9 A;  3JW3 A;  3NXO A;  3NXT A;  4CD2 A;  1E26 A;  1CD2 A;  3L3R A;  3TQ9 A;  2W9H A;  3I3R A;  2C2S A;  3DL5 A;  1RC4 A;  5FDA A;  3D80 A;  4FHB A;  5HSU A;  3S7A A;  1DR3 A;  2W3A A;  1HFQ A;  5DFR A;  3JWK A;  4GH8 A;  3UM8 A;  1IA4 A;  3EEL A;  1BZF A;  3NXV A;  4KY8 A;  1DAJ A;  4DDR A;  3KJS A;  2W9S A;  4XE6 X;  2HXV A;  3GHC A;  5HF2 X;  4PSS A;  1DRF A;  4ELB A;  2HM9 A;  3FL8 A;  3SRR X;  1JOL A;  4HA9 A;  3RO9 A;  3TQB A;  3SQY X;  3EEK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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