1DHIA

Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPASLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 45
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1993-10-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1dhiA00
1DRAA 2W3WA 3S7AA 3QLSA 4RGCA 3INVA 4HA9A 4HA7A 3ROAA 1VJ3A 3QGTA 2D0KA 3FRDX 4XT4A 1DRFA 5HT5A 1U70A 3TQBA 1HFQA 2INQA 2HQPA 3FRFX 4KNEA 1DRBA 2BLAA 4X5HA 1BZFA 4H97A 2D5NA 2ZZAA 2BLBA 1RA9A 3JWFA 4EILA 1DLRA 3SA1A 3CD2A 1HFRA 1BOZA 3Q1HA 3DG8A 4FHBA 4DDRA 4PTJA 4KJJA 3GI2A 4HOFA 1DR2A 3K74A 4CD2A 3DAUA 3FL8A 1PD8A 4KYAA 1DRHA 1RB3A 4P66A 1J3IA 4PSTA 4QJCA 3F91A 2W3MA 3RG9A 1IA2A 2HM9A 2JYBA 2W3AA 3SRWX 1IA3A 1DYHA 4IXFX 3NXTA 3KFYA 4EIZA 1YHOA 1DAJA 3FY8X 3SQYX 4X5GA 3NXVA 5HPBA 3F8ZA 1M79A 2XW7A 1DG7A 2LF1A 3GHCA 2BL9A 3QFXA 3FQOA 3NZCX 1U71A 1DHIA 3SH2A 3UM8A 5ECXA 1D1GA 4XE6X 2W3VA 1AOEA 3F8YA 6DFRA 4IXED 3FYVX 3JWCA 3DRCA 3KY8A 4Q0EA 2DHFA 2FZHA 3DATA 2FZIA 2KGKA 3FQVA 3RO9A 4H96A 3GHVA 1AO8A 3DL5A 3FS6A 4ECKA 1KMVA 3NXXA 3QL3A 1ZDRA 1AI9A 1LUDA 4KEBA 3E0BA 3F0BX 3QLRA 5U26A 1S3WA 1DDSA 4DP3A 2CIGA 3FL9A 1JUVA 1PDBA 1JOMA 3SAIA 4KBNA 1U72A 2OBCA 1CD2A 5CC9A 3FYWX 3IROA 1DREA 1MVTA 3IA5A 1DLSA 3QG2A 3NXYA 2W9GA 3JW3A 5DFRA 3JWMA 3FY9X 2L28A 3F0XX 4XRBA 3TQAA 2ANQA 4EJ1A 5HVEA 4KAKA 5HI6A 1RX7A 2O7PA 4KJKA 3QL0A 3FQCA 1RX8A 3SRSX 4ELGA 4PTHA 5JG0X 1S3YA 4I1NA 1DIUA 1JOLA 3K45A 4Q67A 2OIPA 4I13A 4X5FA 4QLEA 3NZAX 5FDAA 3UM5A 3NXOA 1VDRA 3JSUA 3TQ9A 4NX7A 1DR7A 3D84X 3SA2A 4KFJA 1LY3A 4FGHA 3NU0A 3F0QX 3CSEA 4PSSA 2G6VA 1IA4A 4KY4A 4P3RA 1DISA 4HOEA 3JTWA 3IA4A 4LEKX 4XT5A 4PSYA 3FQFA 1RX5A 4KM0A 4P3QA 4M2XA 2AZNA 1J3KA 3F0VX 2B3ZA 3SRUX 4Q0DA 5HT4A 3FQ0A 4M6LA 1DR6A 1RF7A 1RE7A 5U27A 4NX6A 4PDJA 3QLXA 3TD8A 2BLCA 4LAEX 3N0HA 2ANOA 1S3VA 1IA1A 1KMSA 4KL9A 1DHFA 3I3RA 3R33A 5HSUA 3LG4A 4LAHX 3EEMA 4M6JA 2C2SA 3IX9A 1DDRA 4QI9A 4QJZD 4X5JA 3CL9A 1RH3A 3ZPCA 1RA1A 4DPDA 5JA3A 3NTZA 4DPHA 4ELBA 4H95A 3QLZA 3QLWA 1RA2A 4KM2A 3EEJA 1DR1A 1DR4A 4G95A 3HBBA 1TDRA 1QZFA 1SEJA 5HUIA 1M78A 2HXVA 1DG5A 3SRQX 3FRBX 1CZ3A 3FQZA 1S3UA 5HVBA 3EX8A 3JWKA 1RX2A 1DYIA 4XECX 5HSRA 4M6KA 4DFRA 1DYRA 1RA3A 3OAFA 3F0SX 1RA8A 2W9SA 3KGYA 2H2QA 5HQZA 3K2HA 4G3MA 1DG8A 1J3JA 3EEKA 4ELFA 5DXVA 3KJSA 4EIGA 4OR7A 4ELEA 1DYJA 3I8AX 3EELA 3TQ8A 3FRAX 2W3BA 4XT7A 3NZDA 3NZBX 4P68A 7DFRA 3D80A 4XT6A 2W9HA 2QK8A 5E8QA 2ITHA 2CD2A 1PD9A 3K47A 4KJLA 1KLKA 1MVSA 3GHWA 3SR5X 4M7UA 3FREX 1RB2A 3QYOA 3SRRX 8DFRA 4G8ZX 3DGAA 4QHVA 4Q6AA 3NZ6X 3JVXA 4OSGA 3S3VA 3QLYA 2DRCA 1OHKA 3M09A 4QLFA 3KJRA 3M08A 2P4GA 3QYLA 5ECCA 3IRNA 1RD7A 3F0UX 4IXGX 1RX6A 2W9TA 4KD7A 1RX1A 1LY4A 4LAGX 3EIGA 5EAJA 2FZJA 1RG7A 4M7VA 4KLXA 3IRMA 5CCCA 3SGYA 1OHJA 1DR5A 1DR3A 3S9UA 3CLBA 2GD9A 3HJ3A 3DL6A 4XT8A 3UM6A 4ELHA 1RX9A 4QLGA 1RX3A 3L3RA 3VCOA 3NRRA 4FGGA 5HF0X 1E26A 4GH8A 3DFRA 3NZ9X 4KY8A 1RC4A 3JW5A 3GYFA 5HQYA 1HFPA 2C2TA 4TU5X 5HF2X 1DHJA 3OCHA 3NXRA 4H98A 1RX4A 1M7AA 4HOGA 4X5IA 3ZPGA 1DF7A
chains in the Genus database with same CATH superfamily
1DRAA 2W3WA 3S7AA 3QLSA 4RGCA 3INVA 4HA9A 4HA7A 3ROAA 1VJ3A 3QGTA 2D0KA 3FRDX 4XT4A 1DRFA 5HT5A 1U70A 3TQBA 1HFQA 2INQA 2HQPA 3FRFX 4KNEA 1DRBA 2BLAA 4X5HA 1BZFA 4H97A 2D5NA 2ZZAA 2BLBA 1RA9A 3JWFA 4EILA 1DLRA 3SA1A 3CD2A 1HFRA 1BOZA 3Q1HA 3DG8A 4FHBA 4DDRA 4PTJA 4KJJA 3GI2A 4HOFA 1DR2A 3K74A 4CD2A 3DAUA 3FL8A 1PD8A 4KYAA 1DRHA 1RB3A 4P66A 1J3IA 4PSTA 4QJCA 3F91A 2W3MA 3RG9A 1IA2A 2HM9A 2JYBA 2W3AA 3SRWX 1IA3A 1DYHA 4IXFX 3NXTA 3KFYA 4EIZA 1YHOA 1DAJA 3FY8X 3SQYX 4X5GA 3NXVA 5HPBA 3F8ZA 1M79A 2XW7A 1DG7A 2LF1A 3GHCA 2BL9A 3QFXA 3FQOA 3NZCX 1U71A 1DHIA 3SH2A 3UM8A 5ECXA 1D1GA 4XE6X 2W3VA 1AOEA 3F8YA 6DFRA 4IXED 3FYVX 3JWCA 3DRCA 3KY8A 4Q0EA 2DHFA 2FZHA 3DATA 2FZIA 2KGKA 3FQVA 3RO9A 4H96A 3GHVA 1AO8A 3DL5A 3FS6A 4ECKA 1KMVA 3NXXA 3QL3A 1ZDRA 1AI9A 1LUDA 4KEBA 3E0BA 3F0BX 3QLRA 5U26A 1S3WA 1DDSA 4DP3A 2CIGA 3FL9A 1JUVA 1PDBA 1JOMA 3SAIA 4KBNA 1U72A 2OBCA 1CD2A 5CC9A 3FYWX 3IROA 1DREA 1MVTA 3IA5A 1DLSA 3QG2A 3NXYA 2W9GA 3JW3A 5DFRA 3JWMA 3FY9X 2L28A 3F0XX 4XRBA 3TQAA 2ANQA 4EJ1A 5HVEA 4KAKA 5HI6A 1RX7A 2O7PA 4KJKA 3QL0A 3FQCA 1RX8A 3SRSX 4ELGA 4PTHA 5JG0X 1S3YA 4I1NA 1DIUA 1JOLA 3K45A 4Q67A 2OIPA 4I13A 4X5FA 4QLEA 3NZAX 5FDAA 3UM5A 3NXOA 1VDRA 3JSUA 3TQ9A 4NX7A 1DR7A 3D84X 3SA2A 4KFJA 1LY3A 4FGHA 3NU0A 3F0QX 3CSEA 4PSSA 2G6VA 1IA4A 4KY4A 4P3RA 1DISA 4HOEA 3JTWA 3IA4A 4LEKX 4XT5A 4PSYA 3FQFA 1RX5A 4KM0A 4P3QA 4M2XA 2AZNA 1J3KA 3F0VX 2B3ZA 3SRUX 4Q0DA 5HT4A 3FQ0A 4M6LA 1DR6A 1RF7A 1RE7A 5U27A 4NX6A 4PDJA 3QLXA 3TD8A 2BLCA 4LAEX 3N0HA 2ANOA 1S3VA 1IA1A 1KMSA 4KL9A 1DHFA 3I3RA 3R33A 5HSUA 3LG4A 4LAHX 3EEMA 4M6JA 2C2SA 3IX9A 1DDRA 4QI9A 4QJZD 4X5JA 3CL9A 1RH3A 3ZPCA 1RA1A 4DPDA 5JA3A 3NTZA 4DPHA 4ELBA 4H95A 3QLZA 3QLWA 1RA2A 4KM2A 3EEJA 1DR1A 1DR4A 4G95A 3HBBA 1TDRA 1QZFA 1SEJA 5HUIA 1M78A 2HXVA 1DG5A 3SRQX 3FRBX 1CZ3A 3FQZA 1S3UA 5HVBA 3EX8A 3JWKA 1RX2A 1DYIA 4XECX 5HSRA 4M6KA 4DFRA 1DYRA 1RA3A 3OAFA 3F0SX 1RA8A 2W9SA 3KGYA 2H2QA 5HQZA 3K2HA 4G3MA 1DG8A 1J3JA 3EEKA 4ELFA 5DXVA 3KJSA 4EIGA 4OR7A 4ELEA 1DYJA 3I8AX 3EELA 3TQ8A 3FRAX 2W3BA 4XT7A 3NZDA 3NZBX 4P68A 7DFRA 3D80A 4XT6A 2W9HA 2QK8A 5E8QA 2ITHA 2CD2A 1PD9A 3K47A 4KJLA 1KLKA 1MVSA 3GHWA 3SR5X 4M7UA 3FREX 1RB2A 3QYOA 3SRRX 8DFRA 4G8ZX 3DGAA 4QHVA 4Q6AA 3NZ6X 3JVXA 4OSGA 3S3VA 3QLYA 2DRCA 1OHKA 3M09A 4QLFA 3KJRA 3M08A 2P4GA 3QYLA 5ECCA 3IRNA 1RD7A 3F0UX 4IXGX 1RX6A 2W9TA 4KD7A 1RX1A 1LY4A 4LAGX 3EIGA 5EAJA 2FZJA 1RG7A 4M7VA 4KLXA 3IRMA 5CCCA 3SGYA 1OHJA 1DR5A 1DR3A 3S9UA 3CLBA 2GD9A 3HJ3A 3DL6A 4XT8A 3UM6A 4ELHA 1RX9A 4QLGA 1RX3A 3L3RA 3VCOA 3NRRA 4FGGA 5HF0X 1E26A 4GH8A 3DFRA 3NZ9X 4KY8A 1RC4A 3JW5A 3GYFA 5HQYA 1HFPA 2C2TA 4TU5X 5HF2X 1DHJA 3OCHA 3NXRA 4H98A 1RX4A 1M7AA 4HOGA 4X5IA 3ZPGA 1DF7A
chains in the Genus database with same CATH topology
1DRAA 2W3WA 3S7AA 3QLSA 4RGCA 3INVA 4HA9A 4HA7A 3ROAA 1VJ3A 3QGTA 2D0KA 3FRDX 4XT4A 1DRFA 5HT5A 1U70A 3TQBA 1HFQA 2INQA 2HQPA 3FRFX 4KNEA 1DRBA 2BLAA 4X5HA 1BZFA 4H97A 2D5NA 2ZZAA 2BLBA 1RA9A 3JWFA 4EILA 1DLRA 3SA1A 3CD2A 1HFRA 1BOZA 3Q1HA 3DG8A 4FHBA 4DDRA 4PTJA 4KJJA 3GI2A 4HOFA 1DR2A 3K74A 4CD2A 3DAUA 3FL8A 1PD8A 4KYAA 1DRHA 1RB3A 4P66A 1J3IA 4PSTA 4QJCA 3F91A 2W3MA 3RG9A 1IA2A 2HM9A 2JYBA 2W3AA 3SRWX 1IA3A 1DYHA 4IXFX 3NXTA 3KFYA 4EIZA 1YHOA 1DAJA 3FY8X 3SQYX 4X5GA 3NXVA 5HPBA 3F8ZA 1M79A 2XW7A 1DG7A 2LF1A 3GHCA 2BL9A 3QFXA 3FQOA 3NZCX 1U71A 1DHIA 3SH2A 3UM8A 5ECXA 1D1GA 4XE6X 2W3VA 1AOEA 3F8YA 6DFRA 4IXED 3FYVX 3JWCA 3DRCA 3KY8A 4Q0EA 2DHFA 2FZHA 3DATA 2FZIA 2KGKA 3FQVA 3RO9A 4H96A 3GHVA 1AO8A 3DL5A 3FS6A 4ECKA 1KMVA 3NXXA 3QL3A 1ZDRA 1AI9A 1LUDA 4KEBA 3E0BA 3F0BX 3QLRA 5U26A 1S3WA 1DDSA 4DP3A 2CIGA 3FL9A 1JUVA 1PDBA 1JOMA 3SAIA 4KBNA 1U72A 2OBCA 1CD2A 5CC9A 3FYWX 3IROA 1DREA 1MVTA 3IA5A 1DLSA 3QG2A 3NXYA 2W9GA 3JW3A 5DFRA 3JWMA 3FY9X 2L28A 3F0XX 4XRBA 3TQAA 2ANQA 4EJ1A 5HVEA 4KAKA 5HI6A 1RX7A 2O7PA 4KJKA 3QL0A 3FQCA 1RX8A 3SRSX 4ELGA 4PTHA 5JG0X 1S3YA 4I1NA 1DIUA 1JOLA 3K45A 4Q67A 2OIPA 4I13A 4X5FA 4QLEA 3NZAX 5FDAA 3UM5A 3NXOA 1VDRA 3JSUA 3TQ9A 4NX7A 1DR7A 3D84X 3SA2A 4KFJA 1LY3A 4FGHA 3NU0A 3F0QX 3CSEA 4PSSA 2G6VA 1IA4A 4KY4A 4P3RA 1DISA 4HOEA 3JTWA 3IA4A 4LEKX 4XT5A 4PSYA 3FQFA 1RX5A 4KM0A 4P3QA 4M2XA 2AZNA 1J3KA 3F0VX 2B3ZA 3SRUX 4Q0DA 5HT4A 3FQ0A 4M6LA 1DR6A 1RF7A 1RE7A 5U27A 4NX6A 4PDJA 3QLXA 3TD8A 2BLCA 4LAEX 3N0HA 2ANOA 1S3VA 1IA1A 1KMSA 4KL9A 1DHFA 3I3RA 3R33A 5HSUA 3LG4A 4LAHX 3EEMA 4M6JA 2C2SA 3IX9A 1DDRA 4QI9A 4QJZD 4X5JA 3CL9A 1RH3A 3ZPCA 1RA1A 4DPDA 5JA3A 3NTZA 4DPHA 4ELBA 4H95A 3QLZA 3QLWA 1RA2A 4KM2A 3EEJA 1DR1A 1DR4A 4G95A 3HBBA 1TDRA 1QZFA 1SEJA 5HUIA 1M78A 2HXVA 1DG5A 3SRQX 3FRBX 1CZ3A 3FQZA 1S3UA 5HVBA 3EX8A 3JWKA 1RX2A 1DYIA 4XECX 5HSRA 4M6KA 4DFRA 1DYRA 1RA3A 3OAFA 3F0SX 1RA8A 2W9SA 3KGYA 2H2QA 5HQZA 3K2HA 4G3MA 1DG8A 1J3JA 3EEKA 4ELFA 5DXVA 3KJSA 4EIGA 4OR7A 4ELEA 1DYJA 3I8AX 3EELA 3TQ8A 3FRAX 2W3BA 4XT7A 3NZDA 3NZBX 4P68A 7DFRA 3D80A 4XT6A 2W9HA 2QK8A 5E8QA 2ITHA 2CD2A 1PD9A 3K47A 4KJLA 1KLKA 1MVSA 3GHWA 3SR5X 4M7UA 3FREX 1RB2A 3QYOA 3SRRX 8DFRA 4G8ZX 3DGAA 4QHVA 4Q6AA 3NZ6X 3JVXA 4OSGA 3S3VA 3QLYA 2DRCA 1OHKA 3M09A 4QLFA 3KJRA 3M08A 2P4GA 3QYLA 5ECCA 3IRNA 1RD7A 3F0UX 4IXGX 1RX6A 2W9TA 4KD7A 1RX1A 1LY4A 4LAGX 3EIGA 5EAJA 2FZJA 1RG7A 4M7VA 4KLXA 3IRMA 5CCCA 3SGYA 1OHJA 1DR5A 1DR3A 3S9UA 3CLBA 2GD9A 3HJ3A 3DL6A 4XT8A 3UM6A 4ELHA 1RX9A 4QLGA 1RX3A 3L3RA 3VCOA 3NRRA 4FGGA 5HF0X 1E26A 4GH8A 3DFRA 3NZ9X 4KY8A 1RC4A 3JW5A 3GYFA 5HQYA 1HFPA 2C2TA 4TU5X 5HF2X 1DHJA 3OCHA 3NXRA 4H98A 1RX4A 1M7AA 4HOGA 4X5IA 3ZPGA 1DF7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DRA A;  2W3W A;  3S7A A;  3QLS A;  4RGC A;  3INV A;  4HA9 A;  4HA7 A;  3ROA A;  1VJ3 A;  3QGT A;  2D0K A;  3FRD X;  4XT4 A;  1DRF A;  5HT5 A;  1U70 A;  3TQB A;  1HFQ A;  2INQ A;  2HQP A;  3FRF X;  4KNE A;  1DRB A;  2BLA A;  4X5H A;  1BZF A;  4H97 A;  2D5N A;  2ZZA A;  2BLB A;  1RA9 A;  3JWF A;  4EIL A;  1DLR A;  3SA1 A;  3CD2 A;  1HFR A;  1BOZ A;  3Q1H A;  3DG8 A;  4FHB A;  4DDR A;  4PTJ A;  4KJJ A;  3GI2 A;  4HOF A;  1DR2 A;  3K74 A;  4CD2 A;  3DAU A;  3FL8 A;  1PD8 A;  4KYA A;  1DRH A;  1RB3 A;  4P66 A;  1J3I A;  4PST A;  4QJC A;  3F91 A;  2W3M A;  3RG9 A;  1IA2 A;  2HM9 A;  2JYB A;  2W3A A;  3SRW X;  1IA3 A;  1DYH A;  4IXF X;  3NXT A;  3KFY A;  4EIZ A;  1YHO A;  1DAJ A;  3FY8 X;  3SQY X;  4X5G A;  3NXV A;  5HPB A;  3F8Z A;  1M79 A;  2XW7 A;  1DG7 A;  2LF1 A;  3GHC A;  2BL9 A;  3QFX A;  3FQO A;  3NZC X;  1U71 A;  1DHI A;  3SH2 A;  3UM8 A;  5ECX A;  1D1G A;  4XE6 X;  2W3V A;  1AOE A;  3F8Y A;  6DFR A;  4IXE D;  3FYV X;  3JWC A;  3DRC A;  3KY8 A;  4Q0E A;  2DHF A;  2FZH A;  3DAT A;  2FZI A;  2KGK A;  3FQV A;  3RO9 A;  4H96 A;  3GHV A;  1AO8 A;  3DL5 A;  3FS6 A;  4ECK A;  1KMV A;  3NXX A;  3QL3 A;  1ZDR A;  1AI9 A;  1LUD A;  4KEB A;  3E0B A;  3F0B X;  3QLR A;  5U26 A;  1S3W A;  1DDS A;  4DP3 A;  2CIG A;  3FL9 A;  1JUV A;  1PDB A;  1JOM A;  3SAI A;  4KBN A;  1U72 A;  2OBC A;  1CD2 A;  5CC9 A;  3FYW X;  3IRO A;  1DRE A;  1MVT A;  3IA5 A;  1DLS A;  3QG2 A;  3NXY A;  2W9G A;  3JW3 A;  5DFR A;  3JWM A;  3FY9 X;  2L28 A;  3F0X X;  4XRB A;  3TQA A;  2ANQ A;  4EJ1 A;  5HVE A;  4KAK A;  5HI6 A;  1RX7 A;  2O7P A;  4KJK A;  3QL0 A;  3FQC A;  1RX8 A;  3SRS X;  4ELG A;  4PTH A;  5JG0 X;  1S3Y A;  4I1N A;  1DIU A;  1JOL A;  3K45 A;  4Q67 A;  2OIP A;  4I13 A;  4X5F A;  4QLE A;  3NZA X;  5FDA A;  3UM5 A;  3NXO A;  1VDR A;  3JSU A;  3TQ9 A;  4NX7 A;  1DR7 A;  3D84 X;  3SA2 A;  4KFJ A;  1LY3 A;  4FGH A;  3NU0 A;  3F0Q X;  3CSE A;  4PSS A;  2G6V A;  1IA4 A;  4KY4 A;  4P3R A;  1DIS A;  4HOE A;  3JTW A;  3IA4 A;  4LEK X;  4XT5 A;  4PSY A;  3FQF A;  1RX5 A;  4KM0 A;  4P3Q A;  4M2X A;  2AZN A;  1J3K A;  3F0V X;  2B3Z A;  3SRU X;  4Q0D A;  5HT4 A;  3FQ0 A;  4M6L A;  1DR6 A;  1RF7 A;  1RE7 A;  5U27 A;  4NX6 A;  4PDJ A;  3QLX A;  3TD8 A;  2BLC A;  4LAE X;  3N0H A;  2ANO A;  1S3V A;  1IA1 A;  1KMS A;  4KL9 A;  1DHF A;  3I3R A;  3R33 A;  5HSU A;  3LG4 A;  4LAH X;  3EEM A;  4M6J A;  2C2S A;  3IX9 A;  1DDR A;  4QI9 A;  4QJZ D;  4X5J A;  3CL9 A;  1RH3 A;  3ZPC A;  1RA1 A;  4DPD A;  5JA3 A;  3NTZ A;  4DPH A;  4ELB A;  4H95 A;  3QLZ A;  3QLW A;  1RA2 A;  4KM2 A;  3EEJ A;  1DR1 A;  1DR4 A;  4G95 A;  3HBB A;  1TDR A;  1QZF A;  1SEJ A;  5HUI A;  1M78 A;  2HXV A;  1DG5 A;  3SRQ X;  3FRB X;  1CZ3 A;  3FQZ A;  1S3U A;  5HVB A;  3EX8 A;  3JWK A;  1RX2 A;  1DYI A;  4XEC X;  5HSR A;  4M6K A;  4DFR A;  1DYR A;  1RA3 A;  3OAF A;  3F0S X;  1RA8 A;  2W9S A;  3KGY A;  2H2Q A;  5HQZ A;  3K2H A;  4G3M A;  1DG8 A;  1J3J A;  3EEK A;  4ELF A;  5DXV A;  3KJS A;  4EIG A;  4OR7 A;  4ELE A;  1DYJ A;  3I8A X;  3EEL A;  3TQ8 A;  3FRA X;  2W3B A;  4XT7 A;  3NZD A;  3NZB X;  4P68 A;  7DFR A;  3D80 A;  4XT6 A;  2W9H A;  2QK8 A;  5E8Q A;  2ITH A;  2CD2 A;  1PD9 A;  3K47 A;  4KJL A;  1KLK A;  1MVS A;  3GHW A;  3SR5 X;  4M7U A;  3FRE X;  1RB2 A;  3QYO A;  3SRR X;  8DFR A;  4G8Z X;  3DGA A;  4QHV A;  4Q6A A;  3NZ6 X;  3JVX A;  4OSG A;  3S3V A;  3QLY A;  2DRC A;  1OHK A;  3M09 A;  4QLF A;  3KJR A;  3M08 A;  2P4G A;  3QYL A;  5ECC A;  3IRN A;  1RD7 A;  3F0U X;  4IXG X;  1RX6 A;  2W9T A;  4KD7 A;  1RX1 A;  1LY4 A;  4LAG X;  3EIG A;  5EAJ A;  2FZJ A;  1RG7 A;  4M7V A;  4KLX A;  3IRM A;  5CCC A;  3SGY A;  1OHJ A;  1DR5 A;  1DR3 A;  3S9U A;  3CLB A;  2GD9 A;  3HJ3 A;  3DL6 A;  4XT8 A;  3UM6 A;  4ELH A;  1RX9 A;  4QLG A;  1RX3 A;  3L3R A;  3VCO A;  3NRR A;  4FGG A;  5HF0 X;  1E26 A;  4GH8 A;  3DFR A;  3NZ9 X;  4KY8 A;  1RC4 A;  3JW5 A;  3GYF A;  5HQY A;  1HFP A;  2C2T A;  4TU5 X;  5HF2 X;  1DHJ A;  3OCH A;  3NXR A;  4H98 A;  1RX4 A;  1M7A A;  4HOG A;  4X5I A;  3ZPG A;  1DF7 A; 
#chains in the Genus database with same CATH topology
 1DRA A;  2W3W A;  3S7A A;  3QLS A;  4RGC A;  3INV A;  4HA9 A;  4HA7 A;  3ROA A;  1VJ3 A;  3QGT A;  2D0K A;  3FRD X;  4XT4 A;  1DRF A;  5HT5 A;  1U70 A;  3TQB A;  1HFQ A;  2INQ A;  2HQP A;  3FRF X;  4KNE A;  1DRB A;  2BLA A;  4X5H A;  1BZF A;  4H97 A;  2D5N A;  2ZZA A;  2BLB A;  1RA9 A;  3JWF A;  4EIL A;  1DLR A;  3SA1 A;  3CD2 A;  1HFR A;  1BOZ A;  3Q1H A;  3DG8 A;  4FHB A;  4DDR A;  4PTJ A;  4KJJ A;  3GI2 A;  4HOF A;  1DR2 A;  3K74 A;  4CD2 A;  3DAU A;  3FL8 A;  1PD8 A;  4KYA A;  1DRH A;  1RB3 A;  4P66 A;  1J3I A;  4PST A;  4QJC A;  3F91 A;  2W3M A;  3RG9 A;  1IA2 A;  2HM9 A;  2JYB A;  2W3A A;  3SRW X;  1IA3 A;  1DYH A;  4IXF X;  3NXT A;  3KFY A;  4EIZ A;  1YHO A;  1DAJ A;  3FY8 X;  3SQY X;  4X5G A;  3NXV A;  5HPB A;  3F8Z A;  1M79 A;  2XW7 A;  1DG7 A;  2LF1 A;  3GHC A;  2BL9 A;  3QFX A;  3FQO A;  3NZC X;  1U71 A;  1DHI A;  3SH2 A;  3UM8 A;  5ECX A;  1D1G A;  4XE6 X;  2W3V A;  1AOE A;  3F8Y A;  6DFR A;  4IXE D;  3FYV X;  3JWC A;  3DRC A;  3KY8 A;  4Q0E A;  2DHF A;  2FZH A;  3DAT A;  2FZI A;  2KGK A;  3FQV A;  3RO9 A;  4H96 A;  3GHV A;  1AO8 A;  3DL5 A;  3FS6 A;  4ECK A;  1KMV A;  3NXX A;  3QL3 A;  1ZDR A;  1AI9 A;  1LUD A;  4KEB A;  3E0B A;  3F0B X;  3QLR A;  5U26 A;  1S3W A;  1DDS A;  4DP3 A;  2CIG A;  3FL9 A;  1JUV A;  1PDB A;  1JOM A;  3SAI A;  4KBN A;  1U72 A;  2OBC A;  1CD2 A;  5CC9 A;  3FYW X;  3IRO A;  1DRE A;  1MVT A;  3IA5 A;  1DLS A;  3QG2 A;  3NXY A;  2W9G A;  3JW3 A;  5DFR A;  3JWM A;  3FY9 X;  2L28 A;  3F0X X;  4XRB A;  3TQA A;  2ANQ A;  4EJ1 A;  5HVE A;  4KAK A;  5HI6 A;  1RX7 A;  2O7P A;  4KJK A;  3QL0 A;  3FQC A;  1RX8 A;  3SRS X;  4ELG A;  4PTH A;  5JG0 X;  1S3Y A;  4I1N A;  1DIU A;  1JOL A;  3K45 A;  4Q67 A;  2OIP A;  4I13 A;  4X5F A;  4QLE A;  3NZA X;  5FDA A;  3UM5 A;  3NXO A;  1VDR A;  3JSU A;  3TQ9 A;  4NX7 A;  1DR7 A;  3D84 X;  3SA2 A;  4KFJ A;  1LY3 A;  4FGH A;  3NU0 A;  3F0Q X;  3CSE A;  4PSS A;  2G6V A;  1IA4 A;  4KY4 A;  4P3R A;  1DIS A;  4HOE A;  3JTW A;  3IA4 A;  4LEK X;  4XT5 A;  4PSY A;  3FQF A;  1RX5 A;  4KM0 A;  4P3Q A;  4M2X A;  2AZN A;  1J3K A;  3F0V X;  2B3Z A;  3SRU X;  4Q0D A;  5HT4 A;  3FQ0 A;  4M6L A;  1DR6 A;  1RF7 A;  1RE7 A;  5U27 A;  4NX6 A;  4PDJ A;  3QLX A;  3TD8 A;  2BLC A;  4LAE X;  3N0H A;  2ANO A;  1S3V A;  1IA1 A;  1KMS A;  4KL9 A;  1DHF A;  3I3R A;  3R33 A;  5HSU A;  3LG4 A;  4LAH X;  3EEM A;  4M6J A;  2C2S A;  3IX9 A;  1DDR A;  4QI9 A;  4QJZ D;  4X5J A;  3CL9 A;  1RH3 A;  3ZPC A;  1RA1 A;  4DPD A;  5JA3 A;  3NTZ A;  4DPH A;  4ELB A;  4H95 A;  3QLZ A;  3QLW A;  1RA2 A;  4KM2 A;  3EEJ A;  1DR1 A;  1DR4 A;  4G95 A;  3HBB A;  1TDR A;  1QZF A;  1SEJ A;  5HUI A;  1M78 A;  2HXV A;  1DG5 A;  3SRQ X;  3FRB X;  1CZ3 A;  3FQZ A;  1S3U A;  5HVB A;  3EX8 A;  3JWK A;  1RX2 A;  1DYI A;  4XEC X;  5HSR A;  4M6K A;  4DFR A;  1DYR A;  1RA3 A;  3OAF A;  3F0S X;  1RA8 A;  2W9S A;  3KGY A;  2H2Q A;  5HQZ A;  3K2H A;  4G3M A;  1DG8 A;  1J3J A;  3EEK A;  4ELF A;  5DXV A;  3KJS A;  4EIG A;  4OR7 A;  4ELE A;  1DYJ A;  3I8A X;  3EEL A;  3TQ8 A;  3FRA X;  2W3B A;  4XT7 A;  3NZD A;  3NZB X;  4P68 A;  7DFR A;  3D80 A;  4XT6 A;  2W9H A;  2QK8 A;  5E8Q A;  2ITH A;  2CD2 A;  1PD9 A;  3K47 A;  4KJL A;  1KLK A;  1MVS A;  3GHW A;  3SR5 X;  4M7U A;  3FRE X;  1RB2 A;  3QYO A;  3SRR X;  8DFR A;  4G8Z X;  3DGA A;  4QHV A;  4Q6A A;  3NZ6 X;  3JVX A;  4OSG A;  3S3V A;  3QLY A;  2DRC A;  1OHK A;  3M09 A;  4QLF A;  3KJR A;  3M08 A;  2P4G A;  3QYL A;  5ECC A;  3IRN A;  1RD7 A;  3F0U X;  4IXG X;  1RX6 A;  2W9T A;  4KD7 A;  1RX1 A;  1LY4 A;  4LAG X;  3EIG A;  5EAJ A;  2FZJ A;  1RG7 A;  4M7V A;  4KLX A;  3IRM A;  5CCC A;  3SGY A;  1OHJ A;  1DR5 A;  1DR3 A;  3S9U A;  3CLB A;  2GD9 A;  3HJ3 A;  3DL6 A;  4XT8 A;  3UM6 A;  4ELH A;  1RX9 A;  4QLG A;  1RX3 A;  3L3R A;  3VCO A;  3NRR A;  4FGG A;  5HF0 X;  1E26 A;  4GH8 A;  3DFR A;  3NZ9 X;  4KY8 A;  1RC4 A;  3JW5 A;  3GYF A;  5HQY A;  1HFP A;  2C2T A;  4TU5 X;  5HF2 X;  1DHJ A;  3OCH A;  3NXR A;  4H98 A;  1RX4 A;  1M7A A;  4HOG A;  4X5I A;  3ZPG A;  1DF7 A; 
#chains in the Genus database with same CATH homology
 1DRA A;  2W3W A;  3S7A A;  3QLS A;  4RGC A;  3INV A;  4HA9 A;  4HA7 A;  3ROA A;  1VJ3 A;  3QGT A;  2D0K A;  3FRD X;  4XT4 A;  1DRF A;  5HT5 A;  1U70 A;  3TQB A;  1HFQ A;  2INQ A;  2HQP A;  3FRF X;  4KNE A;  1DRB A;  2BLA A;  4X5H A;  1BZF A;  4H97 A;  2D5N A;  2ZZA A;  2BLB A;  1RA9 A;  3JWF A;  4EIL A;  1DLR A;  3SA1 A;  3CD2 A;  1HFR A;  1BOZ A;  3Q1H A;  3DG8 A;  4FHB A;  4DDR A;  4PTJ A;  4KJJ A;  3GI2 A;  4HOF A;  1DR2 A;  3K74 A;  4CD2 A;  3DAU A;  3FL8 A;  1PD8 A;  4KYA A;  1DRH A;  1RB3 A;  4P66 A;  1J3I A;  4PST A;  4QJC A;  3F91 A;  2W3M A;  3RG9 A;  1IA2 A;  2HM9 A;  2JYB A;  2W3A A;  3SRW X;  1IA3 A;  1DYH A;  4IXF X;  3NXT A;  3KFY A;  4EIZ A;  1YHO A;  1DAJ A;  3FY8 X;  3SQY X;  4X5G A;  3NXV A;  5HPB A;  3F8Z A;  1M79 A;  2XW7 A;  1DG7 A;  2LF1 A;  3GHC A;  2BL9 A;  3QFX A;  3FQO A;  3NZC X;  1U71 A;  1DHI A;  3SH2 A;  3UM8 A;  5ECX A;  1D1G A;  4XE6 X;  2W3V A;  1AOE A;  3F8Y A;  6DFR A;  4IXE D;  3FYV X;  3JWC A;  3DRC A;  3KY8 A;  4Q0E A;  2DHF A;  2FZH A;  3DAT A;  2FZI A;  2KGK A;  3FQV A;  3RO9 A;  4H96 A;  3GHV A;  1AO8 A;  3DL5 A;  3FS6 A;  4ECK A;  1KMV A;  3NXX A;  3QL3 A;  1ZDR A;  1AI9 A;  1LUD A;  4KEB A;  3E0B A;  3F0B X;  3QLR A;  5U26 A;  1S3W A;  1DDS A;  4DP3 A;  2CIG A;  3FL9 A;  1JUV A;  1PDB A;  1JOM A;  3SAI A;  4KBN A;  1U72 A;  2OBC A;  1CD2 A;  5CC9 A;  3FYW X;  3IRO A;  1DRE A;  1MVT A;  3IA5 A;  1DLS A;  3QG2 A;  3NXY A;  2W9G A;  3JW3 A;  5DFR A;  3JWM A;  3FY9 X;  2L28 A;  3F0X X;  4XRB A;  3TQA A;  2ANQ A;  4EJ1 A;  5HVE A;  4KAK A;  5HI6 A;  1RX7 A;  2O7P A;  4KJK A;  3QL0 A;  3FQC A;  1RX8 A;  3SRS X;  4ELG A;  4PTH A;  5JG0 X;  1S3Y A;  4I1N A;  1DIU A;  1JOL A;  3K45 A;  4Q67 A;  2OIP A;  4I13 A;  4X5F A;  4QLE A;  3NZA X;  5FDA A;  3UM5 A;  3NXO A;  1VDR A;  3JSU A;  3TQ9 A;  4NX7 A;  1DR7 A;  3D84 X;  3SA2 A;  4KFJ A;  1LY3 A;  4FGH A;  3NU0 A;  3F0Q X;  3CSE A;  4PSS A;  2G6V A;  1IA4 A;  4KY4 A;  4P3R A;  1DIS A;  4HOE A;  3JTW A;  3IA4 A;  4LEK X;  4XT5 A;  4PSY A;  3FQF A;  1RX5 A;  4KM0 A;  4P3Q A;  4M2X A;  2AZN A;  1J3K A;  3F0V X;  2B3Z A;  3SRU X;  4Q0D A;  5HT4 A;  3FQ0 A;  4M6L A;  1DR6 A;  1RF7 A;  1RE7 A;  5U27 A;  4NX6 A;  4PDJ A;  3QLX A;  3TD8 A;  2BLC A;  4LAE X;  3N0H A;  2ANO A;  1S3V A;  1IA1 A;  1KMS A;  4KL9 A;  1DHF A;  3I3R A;  3R33 A;  5HSU A;  3LG4 A;  4LAH X;  3EEM A;  4M6J A;  2C2S A;  3IX9 A;  1DDR A;  4QI9 A;  4QJZ D;  4X5J A;  3CL9 A;  1RH3 A;  3ZPC A;  1RA1 A;  4DPD A;  5JA3 A;  3NTZ A;  4DPH A;  4ELB A;  4H95 A;  3QLZ A;  3QLW A;  1RA2 A;  4KM2 A;  3EEJ A;  1DR1 A;  1DR4 A;  4G95 A;  3HBB A;  1TDR A;  1QZF A;  1SEJ A;  5HUI A;  1M78 A;  2HXV A;  1DG5 A;  3SRQ X;  3FRB X;  1CZ3 A;  3FQZ A;  1S3U A;  5HVB A;  3EX8 A;  3JWK A;  1RX2 A;  1DYI A;  4XEC X;  5HSR A;  4M6K A;  4DFR A;  1DYR A;  1RA3 A;  3OAF A;  3F0S X;  1RA8 A;  2W9S A;  3KGY A;  2H2Q A;  5HQZ A;  3K2H A;  4G3M A;  1DG8 A;  1J3J A;  3EEK A;  4ELF A;  5DXV A;  3KJS A;  4EIG A;  4OR7 A;  4ELE A;  1DYJ A;  3I8A X;  3EEL A;  3TQ8 A;  3FRA X;  2W3B A;  4XT7 A;  3NZD A;  3NZB X;  4P68 A;  7DFR A;  3D80 A;  4XT6 A;  2W9H A;  2QK8 A;  5E8Q A;  2ITH A;  2CD2 A;  1PD9 A;  3K47 A;  4KJL A;  1KLK A;  1MVS A;  3GHW A;  3SR5 X;  4M7U A;  3FRE X;  1RB2 A;  3QYO A;  3SRR X;  8DFR A;  4G8Z X;  3DGA A;  4QHV A;  4Q6A A;  3NZ6 X;  3JVX A;  4OSG A;  3S3V A;  3QLY A;  2DRC A;  1OHK A;  3M09 A;  4QLF A;  3KJR A;  3M08 A;  2P4G A;  3QYL A;  5ECC A;  3IRN A;  1RD7 A;  3F0U X;  4IXG X;  1RX6 A;  2W9T A;  4KD7 A;  1RX1 A;  1LY4 A;  4LAG X;  3EIG A;  5EAJ A;  2FZJ A;  1RG7 A;  4M7V A;  4KLX A;  3IRM A;  5CCC A;  3SGY A;  1OHJ A;  1DR5 A;  1DR3 A;  3S9U A;  3CLB A;  2GD9 A;  3HJ3 A;  3DL6 A;  4XT8 A;  3UM6 A;  4ELH A;  1RX9 A;  4QLG A;  1RX3 A;  3L3R A;  3VCO A;  3NRR A;  4FGG A;  5HF0 X;  1E26 A;  4GH8 A;  3DFR A;  3NZ9 X;  4KY8 A;  1RC4 A;  3JW5 A;  3GYF A;  5HQY A;  1HFP A;  2C2T A;  4TU5 X;  5HF2 X;  1DHJ A;  3OCH A;  3NXR A;  4H98 A;  1RX4 A;  1M7A A;  4HOG A;  4X5I A;  3ZPG A;  1DF7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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