1DREA

Dihydrofolate reductase complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (oxidized form)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 43
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-11-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1dreA00
1DDRA 5CC9A 4PSSA 1E26A 4QHVA 1HFRA 5HVBA 4P68A 3DG8A 2BLCA 1PD9A 2W9GA 3DL6A 3DL5A 2L28A 1DR2A 1DRHA 3QLYA 1LY4A 2W3WA 2KGKA 4HA9A 1VDRA 3D80A 4DP3A 1J3KA 3UM6A 4QI9A 3SA1A 1J3JA 3DFRA 1J3IA 4IXED 4DDRA 1LY3A 4KY8A 3JW5A 4KJJA 1RA3A 4M7UA 4EIGA 4FGGA 3Q1HA 4G3MA 4H97A 3NXYA 2OBCA 3EIGA 1PD8A 3QLRA 3TQBA 2D5NA 1DR7A 3F8ZA 1DRBA 4KEBA 4EJ1A 5CCCA 4PDJA 1IA1A 4TU5X 3F8YA 4LAEX 1TDRA 5HT4A 4XT7A 5HT5A 3EELA 3KY8A 4X5FA 3QG2A 4M2XA 3TQAA 3DATA 4EIZA 4KBNA 5HSUA 1U71A 1DYIA 3LG4A 3IROA 3ZPCA 2FZHA 1DDSA 2W9TA 3FRFX 1IA3A 2ANOA 3TQ8A 2C2TA 3M09A 2W9HA 4PSYA 4X5JA 1U72A 3SRUX 4PSTA 4RGCA 1S3UA 3SH2A 3FQFA 1VJ3A 5HQZA 4GH8A 1DG7A 1AO8A 3F0BX 3F0UX 4Q0EA 3K45A 3JVXA 3FL9A 3IA5A 1HFQA 3GHCA 4KD7A 2HXVA 2BLBA 5JA3A 4HOEA 1RB2A 1S3VA 1DYRA 1OHKA 3UM5A 1JOMA 2ANQA 4KM2A 5E8QA 1DLRA 4M6KA 3RO9A 1RA8A 4HOGA 2FZJA 4FHBA 4XRBA 3NZ6X 3S9UA 5HPBA 3NZCX 4ELBA 4HA7A 1HFPA 2QK8A 3S3VA 3NXTA 1OHJA 1D1GA 1DREA 5U26A 1CD2A 3IRNA 4KJLA 3E0BA 5EAJA 3GHWA 1DYJA 3CSEA 3IX9A 5ECCA 3F0VX 3KJSA 1DRFA 3FRBX 1MVSA 3EEKA 1IA2A 1RX7A 2GD9A 1DHIA 4EILA 2FZIA 1RG7A 4ECKA 1RX4A 3SRWX 1DLSA 4M6JA 3SGYA 3CD2A 3HBBA 4ELHA 3INVA 3FRDX 5DFRA 2G6VA 3DAUA 1DR1A 4ELEA 4LAGX 6DFRA 4M6LA 4G8ZX 1CZ3A 3FYVX 3NXRA 3KFYA 3SRSX 5HUIA 2W3VA 1RF7A 3FY8X 7DFRA 1YHOA 8DFRA 4OSGA 2W9SA 3I3RA 4NX7A 3QL0A 3QLXA 4QLEA 3JTWA 2D0KA 3IA4A 5U27A 3SRRX 1DF7A 4H98A 4LEKX 2HQPA 3M08A 1QZFA 2B3ZA 3QLZA 3JWCA 4H96A 2HM9A 1RH3A 2LF1A 3NZ9X 1DIUA 3QFXA 1AI9A 1U70A 3FQZA 3NXOA 4XT4A 1M78A 1IA4A 1JOLA 1RX2A 1KLKA 4KL9A 3K74A 1RD7A 1RA2A 3SQYX 1RX1A 3NU0A 4M7VA 3QGTA 3RG9A 1DISA 3EEJA 4G95A 3ROAA 3CL9A 4XECX 3UM8A 3GHVA 1M7AA 1KMSA 3K2HA 3SAIA 1BZFA 2ZZAA 3ZPGA 5DXVA 1RX8A 3F0QX 2CIGA 3FL8A 3N0HA 3S7AA 3SR5X 3F0SX 2INQA 3F91A 1PDBA 2W3BA 3F0XX 5JG0X 5HQYA 4QJCA 1JUVA 3NZAX 3SRQX 2W3AA 4X5HA 3FQCA 3NZBX 5HF2X 5HVEA 1M79A 3DGAA 4KFJA 4Q67A 4Q6AA 1SEJA 3EEMA 4LAHX 1DYHA 3SA2A 3VCOA 2DHFA 4X5GA 4KYAA 4DPHA 3GI2A 3FYWX 4KY4A 3D84X 1RX6A 3KGYA 4XT5A 2H2QA 2ITHA 4I13A 4CD2A 5HI6A 3QL3A 4QLGA 5ECXA 3JW3A 1DRAA 1RB3A 3NRRA 4X5IA 1DR5A 2BL9A 4OR7A 3FQ0A 3R33A 4DFRA 1RA9A 4HOFA 3NZDA 4IXGX 1DR6A 2O7PA 4KNEA 1DR4A 4P66A 2C2SA 5FDAA 4H95A 1MVTA 1RA1A 1RC4A 3TQ9A 3DRCA 1S3YA 4P3QA 4XE6X 4KM0A 2P4GA 3FS6A 1DG5A 1BOZA 3EX8A 1DHFA 5HSRA 1DG8A 1RX3A 3JWKA 3I8AX 4QJZD 4ELGA 3HJ3A 2XW7A 2DRCA 4ELFA 3QLWA 4KJKA 1DR3A 2W3MA 1AOEA 3QLSA 3FQOA 3OAFA 4XT6A 4P3RA 4XT8A 3CLBA 1DAJA 2AZNA 1RE7A 4IXFX 3L3RA 4DPDA 1S3WA 1KMVA 4KAKA 2OIPA 2CD2A 3NXVA 1ZDRA 1LUDA 3OCHA 3JWMA 1DHJA 3FRAX 3NXXA 4QLFA 4KLXA 4PTJA 5HF0X 4FGHA 4PTHA 3FQVA 1RX9A 3TD8A 3NTZA 4Q0DA 2BLAA 3JSUA 3GYFA 1RX5A 3QYLA 3KJRA 4I1NA 4NX6A 3QYOA 3JWFA 3K47A 3FY9X 2JYBA 3FREX 3IRMA
chains in the Genus database with same CATH superfamily
1DDRA 5CC9A 4PSSA 1E26A 4QHVA 1HFRA 5HVBA 4P68A 3DG8A 2BLCA 1PD9A 2W9GA 3DL6A 3DL5A 2L28A 1DR2A 1DRHA 3QLYA 1LY4A 2W3WA 2KGKA 4HA9A 1VDRA 3D80A 4DP3A 1J3KA 3UM6A 4QI9A 3SA1A 1J3JA 3DFRA 1J3IA 4IXED 4DDRA 1LY3A 4KY8A 3JW5A 4KJJA 1RA3A 4M7UA 4EIGA 4FGGA 3Q1HA 4G3MA 4H97A 3NXYA 2OBCA 3EIGA 1PD8A 3QLRA 3TQBA 2D5NA 1DR7A 3F8ZA 1DRBA 4KEBA 4EJ1A 5CCCA 4PDJA 1IA1A 4TU5X 3F8YA 4LAEX 1TDRA 5HT4A 4XT7A 5HT5A 3EELA 3KY8A 4X5FA 3QG2A 4M2XA 3TQAA 3DATA 4EIZA 4KBNA 5HSUA 1U71A 1DYIA 3LG4A 3IROA 3ZPCA 2FZHA 1DDSA 2W9TA 3FRFX 1IA3A 2ANOA 3TQ8A 2C2TA 3M09A 2W9HA 4PSYA 4X5JA 1U72A 3SRUX 4PSTA 4RGCA 1S3UA 3SH2A 3FQFA 1VJ3A 5HQZA 4GH8A 1DG7A 1AO8A 3F0BX 3F0UX 4Q0EA 3K45A 3JVXA 3FL9A 3IA5A 1HFQA 3GHCA 4KD7A 2HXVA 2BLBA 5JA3A 4HOEA 1RB2A 1S3VA 1DYRA 1OHKA 3UM5A 1JOMA 2ANQA 4KM2A 5E8QA 1DLRA 4M6KA 3RO9A 1RA8A 4HOGA 2FZJA 4FHBA 4XRBA 3NZ6X 3S9UA 5HPBA 3NZCX 4ELBA 4HA7A 1HFPA 2QK8A 3S3VA 3NXTA 1OHJA 1D1GA 1DREA 5U26A 1CD2A 3IRNA 4KJLA 3E0BA 5EAJA 3GHWA 1DYJA 3CSEA 3IX9A 5ECCA 3F0VX 3KJSA 1DRFA 3FRBX 1MVSA 3EEKA 1IA2A 1RX7A 2GD9A 1DHIA 4EILA 2FZIA 1RG7A 4ECKA 1RX4A 3SRWX 1DLSA 4M6JA 3SGYA 3CD2A 3HBBA 4ELHA 3INVA 3FRDX 5DFRA 2G6VA 3DAUA 1DR1A 4ELEA 4LAGX 6DFRA 4M6LA 4G8ZX 1CZ3A 3FYVX 3NXRA 3KFYA 3SRSX 5HUIA 2W3VA 1RF7A 3FY8X 7DFRA 1YHOA 8DFRA 4OSGA 2W9SA 3I3RA 4NX7A 3QL0A 3QLXA 4QLEA 3JTWA 2D0KA 3IA4A 5U27A 3SRRX 1DF7A 4H98A 4LEKX 2HQPA 3M08A 1QZFA 2B3ZA 3QLZA 3JWCA 4H96A 2HM9A 1RH3A 2LF1A 3NZ9X 1DIUA 3QFXA 1AI9A 1U70A 3FQZA 3NXOA 4XT4A 1M78A 1IA4A 1JOLA 1RX2A 1KLKA 4KL9A 3K74A 1RD7A 1RA2A 3SQYX 1RX1A 3NU0A 4M7VA 3QGTA 3RG9A 1DISA 3EEJA 4G95A 3ROAA 3CL9A 4XECX 3UM8A 3GHVA 1M7AA 1KMSA 3K2HA 3SAIA 1BZFA 2ZZAA 3ZPGA 5DXVA 1RX8A 3F0QX 2CIGA 3FL8A 3N0HA 3S7AA 3SR5X 3F0SX 2INQA 3F91A 1PDBA 2W3BA 3F0XX 5JG0X 5HQYA 4QJCA 1JUVA 3NZAX 3SRQX 2W3AA 4X5HA 3FQCA 3NZBX 5HF2X 5HVEA 1M79A 3DGAA 4KFJA 4Q67A 4Q6AA 1SEJA 3EEMA 4LAHX 1DYHA 3SA2A 3VCOA 2DHFA 4X5GA 4KYAA 4DPHA 3GI2A 3FYWX 4KY4A 3D84X 1RX6A 3KGYA 4XT5A 2H2QA 2ITHA 4I13A 4CD2A 5HI6A 3QL3A 4QLGA 5ECXA 3JW3A 1DRAA 1RB3A 3NRRA 4X5IA 1DR5A 2BL9A 4OR7A 3FQ0A 3R33A 4DFRA 1RA9A 4HOFA 3NZDA 4IXGX 1DR6A 2O7PA 4KNEA 1DR4A 4P66A 2C2SA 5FDAA 4H95A 1MVTA 1RA1A 1RC4A 3TQ9A 3DRCA 1S3YA 4P3QA 4XE6X 4KM0A 2P4GA 3FS6A 1DG5A 1BOZA 3EX8A 1DHFA 5HSRA 1DG8A 1RX3A 3JWKA 3I8AX 4QJZD 4ELGA 3HJ3A 2XW7A 2DRCA 4ELFA 3QLWA 4KJKA 1DR3A 2W3MA 1AOEA 3QLSA 3FQOA 3OAFA 4XT6A 4P3RA 4XT8A 3CLBA 1DAJA 2AZNA 1RE7A 4IXFX 3L3RA 4DPDA 1S3WA 1KMVA 4KAKA 2OIPA 2CD2A 3NXVA 1ZDRA 1LUDA 3OCHA 3JWMA 1DHJA 3FRAX 3NXXA 4QLFA 4KLXA 4PTJA 5HF0X 4FGHA 4PTHA 3FQVA 1RX9A 3TD8A 3NTZA 4Q0DA 2BLAA 3JSUA 3GYFA 1RX5A 3QYLA 3KJRA 4I1NA 4NX6A 3QYOA 3JWFA 3K47A 3FY9X 2JYBA 3FREX 3IRMA
chains in the Genus database with same CATH topology
1DDRA 5CC9A 4PSSA 1E26A 4QHVA 1HFRA 5HVBA 4P68A 3DG8A 2BLCA 1PD9A 2W9GA 3DL6A 3DL5A 2L28A 1DR2A 1DRHA 3QLYA 1LY4A 2W3WA 2KGKA 4HA9A 1VDRA 3D80A 4DP3A 1J3KA 3UM6A 4QI9A 3SA1A 1J3JA 3DFRA 1J3IA 4IXED 4DDRA 1LY3A 4KY8A 3JW5A 4KJJA 1RA3A 4M7UA 4EIGA 4FGGA 3Q1HA 4G3MA 4H97A 3NXYA 2OBCA 3EIGA 1PD8A 3QLRA 3TQBA 2D5NA 1DR7A 3F8ZA 1DRBA 4KEBA 4EJ1A 5CCCA 4PDJA 1IA1A 4TU5X 3F8YA 4LAEX 1TDRA 5HT4A 4XT7A 5HT5A 3EELA 3KY8A 4X5FA 3QG2A 4M2XA 3TQAA 3DATA 4EIZA 4KBNA 5HSUA 1U71A 1DYIA 3LG4A 3IROA 3ZPCA 2FZHA 1DDSA 2W9TA 3FRFX 1IA3A 2ANOA 3TQ8A 2C2TA 3M09A 2W9HA 4PSYA 4X5JA 1U72A 3SRUX 4PSTA 4RGCA 1S3UA 3SH2A 3FQFA 1VJ3A 5HQZA 4GH8A 1DG7A 1AO8A 3F0BX 3F0UX 4Q0EA 3K45A 3JVXA 3FL9A 3IA5A 1HFQA 3GHCA 4KD7A 2HXVA 2BLBA 5JA3A 4HOEA 1RB2A 1S3VA 1DYRA 1OHKA 3UM5A 1JOMA 2ANQA 4KM2A 5E8QA 1DLRA 4M6KA 3RO9A 1RA8A 4HOGA 2FZJA 4FHBA 4XRBA 3NZ6X 3S9UA 5HPBA 3NZCX 4ELBA 4HA7A 1HFPA 2QK8A 3S3VA 3NXTA 1OHJA 1D1GA 1DREA 5U26A 1CD2A 3IRNA 4KJLA 3E0BA 5EAJA 3GHWA 1DYJA 3CSEA 3IX9A 5ECCA 3F0VX 3KJSA 1DRFA 3FRBX 1MVSA 3EEKA 1IA2A 1RX7A 2GD9A 1DHIA 4EILA 2FZIA 1RG7A 4ECKA 1RX4A 3SRWX 1DLSA 4M6JA 3SGYA 3CD2A 3HBBA 4ELHA 3INVA 3FRDX 5DFRA 2G6VA 3DAUA 1DR1A 4ELEA 4LAGX 6DFRA 4M6LA 4G8ZX 1CZ3A 3FYVX 3NXRA 3KFYA 3SRSX 5HUIA 2W3VA 1RF7A 3FY8X 7DFRA 1YHOA 8DFRA 4OSGA 2W9SA 3I3RA 4NX7A 3QL0A 3QLXA 4QLEA 3JTWA 2D0KA 3IA4A 5U27A 3SRRX 1DF7A 4H98A 4LEKX 2HQPA 3M08A 1QZFA 2B3ZA 3QLZA 3JWCA 4H96A 2HM9A 1RH3A 2LF1A 3NZ9X 1DIUA 3QFXA 1AI9A 1U70A 3FQZA 3NXOA 4XT4A 1M78A 1IA4A 1JOLA 1RX2A 1KLKA 4KL9A 3K74A 1RD7A 1RA2A 3SQYX 1RX1A 3NU0A 4M7VA 3QGTA 3RG9A 1DISA 3EEJA 4G95A 3ROAA 3CL9A 4XECX 3UM8A 3GHVA 1M7AA 1KMSA 3K2HA 3SAIA 1BZFA 2ZZAA 3ZPGA 5DXVA 1RX8A 3F0QX 2CIGA 3FL8A 3N0HA 3S7AA 3SR5X 3F0SX 2INQA 3F91A 1PDBA 2W3BA 3F0XX 5JG0X 5HQYA 4QJCA 1JUVA 3NZAX 3SRQX 2W3AA 4X5HA 3FQCA 3NZBX 5HF2X 5HVEA 1M79A 3DGAA 4KFJA 4Q67A 4Q6AA 1SEJA 3EEMA 4LAHX 1DYHA 3SA2A 3VCOA 2DHFA 4X5GA 4KYAA 4DPHA 3GI2A 3FYWX 4KY4A 3D84X 1RX6A 3KGYA 4XT5A 2H2QA 2ITHA 4I13A 4CD2A 5HI6A 3QL3A 4QLGA 5ECXA 3JW3A 1DRAA 1RB3A 3NRRA 4X5IA 1DR5A 2BL9A 4OR7A 3FQ0A 3R33A 4DFRA 1RA9A 4HOFA 3NZDA 4IXGX 1DR6A 2O7PA 4KNEA 1DR4A 4P66A 2C2SA 5FDAA 4H95A 1MVTA 1RA1A 1RC4A 3TQ9A 3DRCA 1S3YA 4P3QA 4XE6X 4KM0A 2P4GA 3FS6A 1DG5A 1BOZA 3EX8A 1DHFA 5HSRA 1DG8A 1RX3A 3JWKA 3I8AX 4QJZD 4ELGA 3HJ3A 2XW7A 2DRCA 4ELFA 3QLWA 4KJKA 1DR3A 2W3MA 1AOEA 3QLSA 3FQOA 3OAFA 4XT6A 4P3RA 4XT8A 3CLBA 1DAJA 2AZNA 1RE7A 4IXFX 3L3RA 4DPDA 1S3WA 1KMVA 4KAKA 2OIPA 2CD2A 3NXVA 1ZDRA 1LUDA 3OCHA 3JWMA 1DHJA 3FRAX 3NXXA 4QLFA 4KLXA 4PTJA 5HF0X 4FGHA 4PTHA 3FQVA 1RX9A 3TD8A 3NTZA 4Q0DA 2BLAA 3JSUA 3GYFA 1RX5A 3QYLA 3KJRA 4I1NA 4NX6A 3QYOA 3JWFA 3K47A 3FY9X 2JYBA 3FREX 3IRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DDR A;  5CC9 A;  4PSS A;  1E26 A;  4QHV A;  1HFR A;  5HVB A;  4P68 A;  3DG8 A;  2BLC A;  1PD9 A;  2W9G A;  3DL6 A;  3DL5 A;  2L28 A;  1DR2 A;  1DRH A;  3QLY A;  1LY4 A;  2W3W A;  2KGK A;  4HA9 A;  1VDR A;  3D80 A;  4DP3 A;  1J3K A;  3UM6 A;  4QI9 A;  3SA1 A;  1J3J A;  3DFR A;  1J3I A;  4IXE D;  4DDR A;  1LY3 A;  4KY8 A;  3JW5 A;  4KJJ A;  1RA3 A;  4M7U A;  4EIG A;  4FGG A;  3Q1H A;  4G3M A;  4H97 A;  3NXY A;  2OBC A;  3EIG A;  1PD8 A;  3QLR A;  3TQB A;  2D5N A;  1DR7 A;  3F8Z A;  1DRB A;  4KEB A;  4EJ1 A;  5CCC A;  4PDJ A;  1IA1 A;  4TU5 X;  3F8Y A;  4LAE X;  1TDR A;  5HT4 A;  4XT7 A;  5HT5 A;  3EEL A;  3KY8 A;  4X5F A;  3QG2 A;  4M2X A;  3TQA A;  3DAT A;  4EIZ A;  4KBN A;  5HSU A;  1U71 A;  1DYI A;  3LG4 A;  3IRO A;  3ZPC A;  2FZH A;  1DDS A;  2W9T A;  3FRF X;  1IA3 A;  2ANO A;  3TQ8 A;  2C2T A;  3M09 A;  2W9H A;  4PSY A;  4X5J A;  1U72 A;  3SRU X;  4PST A;  4RGC A;  1S3U A;  3SH2 A;  3FQF A;  1VJ3 A;  5HQZ A;  4GH8 A;  1DG7 A;  1AO8 A;  3F0B X;  3F0U X;  4Q0E A;  3K45 A;  3JVX A;  3FL9 A;  3IA5 A;  1HFQ A;  3GHC A;  4KD7 A;  2HXV A;  2BLB A;  5JA3 A;  4HOE A;  1RB2 A;  1S3V A;  1DYR A;  1OHK A;  3UM5 A;  1JOM A;  2ANQ A;  4KM2 A;  5E8Q A;  1DLR A;  4M6K A;  3RO9 A;  1RA8 A;  4HOG A;  2FZJ A;  4FHB A;  4XRB A;  3NZ6 X;  3S9U A;  5HPB A;  3NZC X;  4ELB A;  4HA7 A;  1HFP A;  2QK8 A;  3S3V A;  3NXT A;  1OHJ A;  1D1G A;  1DRE A;  5U26 A;  1CD2 A;  3IRN A;  4KJL A;  3E0B A;  5EAJ A;  3GHW A;  1DYJ A;  3CSE A;  3IX9 A;  5ECC A;  3F0V X;  3KJS A;  1DRF A;  3FRB X;  1MVS A;  3EEK A;  1IA2 A;  1RX7 A;  2GD9 A;  1DHI A;  4EIL A;  2FZI A;  1RG7 A;  4ECK A;  1RX4 A;  3SRW X;  1DLS A;  4M6J A;  3SGY A;  3CD2 A;  3HBB A;  4ELH A;  3INV A;  3FRD X;  5DFR A;  2G6V A;  3DAU A;  1DR1 A;  4ELE A;  4LAG X;  6DFR A;  4M6L A;  4G8Z X;  1CZ3 A;  3FYV X;  3NXR A;  3KFY A;  3SRS X;  5HUI A;  2W3V A;  1RF7 A;  3FY8 X;  7DFR A;  1YHO A;  8DFR A;  4OSG A;  2W9S A;  3I3R A;  4NX7 A;  3QL0 A;  3QLX A;  4QLE A;  3JTW A;  2D0K A;  3IA4 A;  5U27 A;  3SRR X;  1DF7 A;  4H98 A;  4LEK X;  2HQP A;  3M08 A;  1QZF A;  2B3Z A;  3QLZ A;  3JWC A;  4H96 A;  2HM9 A;  1RH3 A;  2LF1 A;  3NZ9 X;  1DIU A;  3QFX A;  1AI9 A;  1U70 A;  3FQZ A;  3NXO A;  4XT4 A;  1M78 A;  1IA4 A;  1JOL A;  1RX2 A;  1KLK A;  4KL9 A;  3K74 A;  1RD7 A;  1RA2 A;  3SQY X;  1RX1 A;  3NU0 A;  4M7V A;  3QGT A;  3RG9 A;  1DIS A;  3EEJ A;  4G95 A;  3ROA A;  3CL9 A;  4XEC X;  3UM8 A;  3GHV A;  1M7A A;  1KMS A;  3K2H A;  3SAI A;  1BZF A;  2ZZA A;  3ZPG A;  5DXV A;  1RX8 A;  3F0Q X;  2CIG A;  3FL8 A;  3N0H A;  3S7A A;  3SR5 X;  3F0S X;  2INQ A;  3F91 A;  1PDB A;  2W3B A;  3F0X X;  5JG0 X;  5HQY A;  4QJC A;  1JUV A;  3NZA X;  3SRQ X;  2W3A A;  4X5H A;  3FQC A;  3NZB X;  5HF2 X;  5HVE A;  1M79 A;  3DGA A;  4KFJ A;  4Q67 A;  4Q6A A;  1SEJ A;  3EEM A;  4LAH X;  1DYH A;  3SA2 A;  3VCO A;  2DHF A;  4X5G A;  4KYA A;  4DPH A;  3GI2 A;  3FYW X;  4KY4 A;  3D84 X;  1RX6 A;  3KGY A;  4XT5 A;  2H2Q A;  2ITH A;  4I13 A;  4CD2 A;  5HI6 A;  3QL3 A;  4QLG A;  5ECX A;  3JW3 A;  1DRA A;  1RB3 A;  3NRR A;  4X5I A;  1DR5 A;  2BL9 A;  4OR7 A;  3FQ0 A;  3R33 A;  4DFR A;  1RA9 A;  4HOF A;  3NZD A;  4IXG X;  1DR6 A;  2O7P A;  4KNE A;  1DR4 A;  4P66 A;  2C2S A;  5FDA A;  4H95 A;  1MVT A;  1RA1 A;  1RC4 A;  3TQ9 A;  3DRC A;  1S3Y A;  4P3Q A;  4XE6 X;  4KM0 A;  2P4G A;  3FS6 A;  1DG5 A;  1BOZ A;  3EX8 A;  1DHF A;  5HSR A;  1DG8 A;  1RX3 A;  3JWK A;  3I8A X;  4QJZ D;  4ELG A;  3HJ3 A;  2XW7 A;  2DRC A;  4ELF A;  3QLW A;  4KJK A;  1DR3 A;  2W3M A;  1AOE A;  3QLS A;  3FQO A;  3OAF A;  4XT6 A;  4P3R A;  4XT8 A;  3CLB A;  1DAJ A;  2AZN A;  1RE7 A;  4IXF X;  3L3R A;  4DPD A;  1S3W A;  1KMV A;  4KAK A;  2OIP A;  2CD2 A;  3NXV A;  1ZDR A;  1LUD A;  3OCH A;  3JWM A;  1DHJ A;  3FRA X;  3NXX A;  4QLF A;  4KLX A;  4PTJ A;  5HF0 X;  4FGH A;  4PTH A;  3FQV A;  1RX9 A;  3TD8 A;  3NTZ A;  4Q0D A;  2BLA A;  3JSU A;  3GYF A;  1RX5 A;  3QYL A;  3KJR A;  4I1N A;  4NX6 A;  3QYO A;  3JWF A;  3K47 A;  3FY9 X;  2JYB A;  3FRE X;  3IRM A; 
#chains in the Genus database with same CATH topology
 1DDR A;  5CC9 A;  4PSS A;  1E26 A;  4QHV A;  1HFR A;  5HVB A;  4P68 A;  3DG8 A;  2BLC A;  1PD9 A;  2W9G A;  3DL6 A;  3DL5 A;  2L28 A;  1DR2 A;  1DRH A;  3QLY A;  1LY4 A;  2W3W A;  2KGK A;  4HA9 A;  1VDR A;  3D80 A;  4DP3 A;  1J3K A;  3UM6 A;  4QI9 A;  3SA1 A;  1J3J A;  3DFR A;  1J3I A;  4IXE D;  4DDR A;  1LY3 A;  4KY8 A;  3JW5 A;  4KJJ A;  1RA3 A;  4M7U A;  4EIG A;  4FGG A;  3Q1H A;  4G3M A;  4H97 A;  3NXY A;  2OBC A;  3EIG A;  1PD8 A;  3QLR A;  3TQB A;  2D5N A;  1DR7 A;  3F8Z A;  1DRB A;  4KEB A;  4EJ1 A;  5CCC A;  4PDJ A;  1IA1 A;  4TU5 X;  3F8Y A;  4LAE X;  1TDR A;  5HT4 A;  4XT7 A;  5HT5 A;  3EEL A;  3KY8 A;  4X5F A;  3QG2 A;  4M2X A;  3TQA A;  3DAT A;  4EIZ A;  4KBN A;  5HSU A;  1U71 A;  1DYI A;  3LG4 A;  3IRO A;  3ZPC A;  2FZH A;  1DDS A;  2W9T A;  3FRF X;  1IA3 A;  2ANO A;  3TQ8 A;  2C2T A;  3M09 A;  2W9H A;  4PSY A;  4X5J A;  1U72 A;  3SRU X;  4PST A;  4RGC A;  1S3U A;  3SH2 A;  3FQF A;  1VJ3 A;  5HQZ A;  4GH8 A;  1DG7 A;  1AO8 A;  3F0B X;  3F0U X;  4Q0E A;  3K45 A;  3JVX A;  3FL9 A;  3IA5 A;  1HFQ A;  3GHC A;  4KD7 A;  2HXV A;  2BLB A;  5JA3 A;  4HOE A;  1RB2 A;  1S3V A;  1DYR A;  1OHK A;  3UM5 A;  1JOM A;  2ANQ A;  4KM2 A;  5E8Q A;  1DLR A;  4M6K A;  3RO9 A;  1RA8 A;  4HOG A;  2FZJ A;  4FHB A;  4XRB A;  3NZ6 X;  3S9U A;  5HPB A;  3NZC X;  4ELB A;  4HA7 A;  1HFP A;  2QK8 A;  3S3V A;  3NXT A;  1OHJ A;  1D1G A;  1DRE A;  5U26 A;  1CD2 A;  3IRN A;  4KJL A;  3E0B A;  5EAJ A;  3GHW A;  1DYJ A;  3CSE A;  3IX9 A;  5ECC A;  3F0V X;  3KJS A;  1DRF A;  3FRB X;  1MVS A;  3EEK A;  1IA2 A;  1RX7 A;  2GD9 A;  1DHI A;  4EIL A;  2FZI A;  1RG7 A;  4ECK A;  1RX4 A;  3SRW X;  1DLS A;  4M6J A;  3SGY A;  3CD2 A;  3HBB A;  4ELH A;  3INV A;  3FRD X;  5DFR A;  2G6V A;  3DAU A;  1DR1 A;  4ELE A;  4LAG X;  6DFR A;  4M6L A;  4G8Z X;  1CZ3 A;  3FYV X;  3NXR A;  3KFY A;  3SRS X;  5HUI A;  2W3V A;  1RF7 A;  3FY8 X;  7DFR A;  1YHO A;  8DFR A;  4OSG A;  2W9S A;  3I3R A;  4NX7 A;  3QL0 A;  3QLX A;  4QLE A;  3JTW A;  2D0K A;  3IA4 A;  5U27 A;  3SRR X;  1DF7 A;  4H98 A;  4LEK X;  2HQP A;  3M08 A;  1QZF A;  2B3Z A;  3QLZ A;  3JWC A;  4H96 A;  2HM9 A;  1RH3 A;  2LF1 A;  3NZ9 X;  1DIU A;  3QFX A;  1AI9 A;  1U70 A;  3FQZ A;  3NXO A;  4XT4 A;  1M78 A;  1IA4 A;  1JOL A;  1RX2 A;  1KLK A;  4KL9 A;  3K74 A;  1RD7 A;  1RA2 A;  3SQY X;  1RX1 A;  3NU0 A;  4M7V A;  3QGT A;  3RG9 A;  1DIS A;  3EEJ A;  4G95 A;  3ROA A;  3CL9 A;  4XEC X;  3UM8 A;  3GHV A;  1M7A A;  1KMS A;  3K2H A;  3SAI A;  1BZF A;  2ZZA A;  3ZPG A;  5DXV A;  1RX8 A;  3F0Q X;  2CIG A;  3FL8 A;  3N0H A;  3S7A A;  3SR5 X;  3F0S X;  2INQ A;  3F91 A;  1PDB A;  2W3B A;  3F0X X;  5JG0 X;  5HQY A;  4QJC A;  1JUV A;  3NZA X;  3SRQ X;  2W3A A;  4X5H A;  3FQC A;  3NZB X;  5HF2 X;  5HVE A;  1M79 A;  3DGA A;  4KFJ A;  4Q67 A;  4Q6A A;  1SEJ A;  3EEM A;  4LAH X;  1DYH A;  3SA2 A;  3VCO A;  2DHF A;  4X5G A;  4KYA A;  4DPH A;  3GI2 A;  3FYW X;  4KY4 A;  3D84 X;  1RX6 A;  3KGY A;  4XT5 A;  2H2Q A;  2ITH A;  4I13 A;  4CD2 A;  5HI6 A;  3QL3 A;  4QLG A;  5ECX A;  3JW3 A;  1DRA A;  1RB3 A;  3NRR A;  4X5I A;  1DR5 A;  2BL9 A;  4OR7 A;  3FQ0 A;  3R33 A;  4DFR A;  1RA9 A;  4HOF A;  3NZD A;  4IXG X;  1DR6 A;  2O7P A;  4KNE A;  1DR4 A;  4P66 A;  2C2S A;  5FDA A;  4H95 A;  1MVT A;  1RA1 A;  1RC4 A;  3TQ9 A;  3DRC A;  1S3Y A;  4P3Q A;  4XE6 X;  4KM0 A;  2P4G A;  3FS6 A;  1DG5 A;  1BOZ A;  3EX8 A;  1DHF A;  5HSR A;  1DG8 A;  1RX3 A;  3JWK A;  3I8A X;  4QJZ D;  4ELG A;  3HJ3 A;  2XW7 A;  2DRC A;  4ELF A;  3QLW A;  4KJK A;  1DR3 A;  2W3M A;  1AOE A;  3QLS A;  3FQO A;  3OAF A;  4XT6 A;  4P3R A;  4XT8 A;  3CLB A;  1DAJ A;  2AZN A;  1RE7 A;  4IXF X;  3L3R A;  4DPD A;  1S3W A;  1KMV A;  4KAK A;  2OIP A;  2CD2 A;  3NXV A;  1ZDR A;  1LUD A;  3OCH A;  3JWM A;  1DHJ A;  3FRA X;  3NXX A;  4QLF A;  4KLX A;  4PTJ A;  5HF0 X;  4FGH A;  4PTH A;  3FQV A;  1RX9 A;  3TD8 A;  3NTZ A;  4Q0D A;  2BLA A;  3JSU A;  3GYF A;  1RX5 A;  3QYL A;  3KJR A;  4I1N A;  4NX6 A;  3QYO A;  3JWF A;  3K47 A;  3FY9 X;  2JYB A;  3FRE X;  3IRM A; 
#chains in the Genus database with same CATH homology
 1DDR A;  5CC9 A;  4PSS A;  1E26 A;  4QHV A;  1HFR A;  5HVB A;  4P68 A;  3DG8 A;  2BLC A;  1PD9 A;  2W9G A;  3DL6 A;  3DL5 A;  2L28 A;  1DR2 A;  1DRH A;  3QLY A;  1LY4 A;  2W3W A;  2KGK A;  4HA9 A;  1VDR A;  3D80 A;  4DP3 A;  1J3K A;  3UM6 A;  4QI9 A;  3SA1 A;  1J3J A;  3DFR A;  1J3I A;  4IXE D;  4DDR A;  1LY3 A;  4KY8 A;  3JW5 A;  4KJJ A;  1RA3 A;  4M7U A;  4EIG A;  4FGG A;  3Q1H A;  4G3M A;  4H97 A;  3NXY A;  2OBC A;  3EIG A;  1PD8 A;  3QLR A;  3TQB A;  2D5N A;  1DR7 A;  3F8Z A;  1DRB A;  4KEB A;  4EJ1 A;  5CCC A;  4PDJ A;  1IA1 A;  4TU5 X;  3F8Y A;  4LAE X;  1TDR A;  5HT4 A;  4XT7 A;  5HT5 A;  3EEL A;  3KY8 A;  4X5F A;  3QG2 A;  4M2X A;  3TQA A;  3DAT A;  4EIZ A;  4KBN A;  5HSU A;  1U71 A;  1DYI A;  3LG4 A;  3IRO A;  3ZPC A;  2FZH A;  1DDS A;  2W9T A;  3FRF X;  1IA3 A;  2ANO A;  3TQ8 A;  2C2T A;  3M09 A;  2W9H A;  4PSY A;  4X5J A;  1U72 A;  3SRU X;  4PST A;  4RGC A;  1S3U A;  3SH2 A;  3FQF A;  1VJ3 A;  5HQZ A;  4GH8 A;  1DG7 A;  1AO8 A;  3F0B X;  3F0U X;  4Q0E A;  3K45 A;  3JVX A;  3FL9 A;  3IA5 A;  1HFQ A;  3GHC A;  4KD7 A;  2HXV A;  2BLB A;  5JA3 A;  4HOE A;  1RB2 A;  1S3V A;  1DYR A;  1OHK A;  3UM5 A;  1JOM A;  2ANQ A;  4KM2 A;  5E8Q A;  1DLR A;  4M6K A;  3RO9 A;  1RA8 A;  4HOG A;  2FZJ A;  4FHB A;  4XRB A;  3NZ6 X;  3S9U A;  5HPB A;  3NZC X;  4ELB A;  4HA7 A;  1HFP A;  2QK8 A;  3S3V A;  3NXT A;  1OHJ A;  1D1G A;  1DRE A;  5U26 A;  1CD2 A;  3IRN A;  4KJL A;  3E0B A;  5EAJ A;  3GHW A;  1DYJ A;  3CSE A;  3IX9 A;  5ECC A;  3F0V X;  3KJS A;  1DRF A;  3FRB X;  1MVS A;  3EEK A;  1IA2 A;  1RX7 A;  2GD9 A;  1DHI A;  4EIL A;  2FZI A;  1RG7 A;  4ECK A;  1RX4 A;  3SRW X;  1DLS A;  4M6J A;  3SGY A;  3CD2 A;  3HBB A;  4ELH A;  3INV A;  3FRD X;  5DFR A;  2G6V A;  3DAU A;  1DR1 A;  4ELE A;  4LAG X;  6DFR A;  4M6L A;  4G8Z X;  1CZ3 A;  3FYV X;  3NXR A;  3KFY A;  3SRS X;  5HUI A;  2W3V A;  1RF7 A;  3FY8 X;  7DFR A;  1YHO A;  8DFR A;  4OSG A;  2W9S A;  3I3R A;  4NX7 A;  3QL0 A;  3QLX A;  4QLE A;  3JTW A;  2D0K A;  3IA4 A;  5U27 A;  3SRR X;  1DF7 A;  4H98 A;  4LEK X;  2HQP A;  3M08 A;  1QZF A;  2B3Z A;  3QLZ A;  3JWC A;  4H96 A;  2HM9 A;  1RH3 A;  2LF1 A;  3NZ9 X;  1DIU A;  3QFX A;  1AI9 A;  1U70 A;  3FQZ A;  3NXO A;  4XT4 A;  1M78 A;  1IA4 A;  1JOL A;  1RX2 A;  1KLK A;  4KL9 A;  3K74 A;  1RD7 A;  1RA2 A;  3SQY X;  1RX1 A;  3NU0 A;  4M7V A;  3QGT A;  3RG9 A;  1DIS A;  3EEJ A;  4G95 A;  3ROA A;  3CL9 A;  4XEC X;  3UM8 A;  3GHV A;  1M7A A;  1KMS A;  3K2H A;  3SAI A;  1BZF A;  2ZZA A;  3ZPG A;  5DXV A;  1RX8 A;  3F0Q X;  2CIG A;  3FL8 A;  3N0H A;  3S7A A;  3SR5 X;  3F0S X;  2INQ A;  3F91 A;  1PDB A;  2W3B A;  3F0X X;  5JG0 X;  5HQY A;  4QJC A;  1JUV A;  3NZA X;  3SRQ X;  2W3A A;  4X5H A;  3FQC A;  3NZB X;  5HF2 X;  5HVE A;  1M79 A;  3DGA A;  4KFJ A;  4Q67 A;  4Q6A A;  1SEJ A;  3EEM A;  4LAH X;  1DYH A;  3SA2 A;  3VCO A;  2DHF A;  4X5G A;  4KYA A;  4DPH A;  3GI2 A;  3FYW X;  4KY4 A;  3D84 X;  1RX6 A;  3KGY A;  4XT5 A;  2H2Q A;  2ITH A;  4I13 A;  4CD2 A;  5HI6 A;  3QL3 A;  4QLG A;  5ECX A;  3JW3 A;  1DRA A;  1RB3 A;  3NRR A;  4X5I A;  1DR5 A;  2BL9 A;  4OR7 A;  3FQ0 A;  3R33 A;  4DFR A;  1RA9 A;  4HOF A;  3NZD A;  4IXG X;  1DR6 A;  2O7P A;  4KNE A;  1DR4 A;  4P66 A;  2C2S A;  5FDA A;  4H95 A;  1MVT A;  1RA1 A;  1RC4 A;  3TQ9 A;  3DRC A;  1S3Y A;  4P3Q A;  4XE6 X;  4KM0 A;  2P4G A;  3FS6 A;  1DG5 A;  1BOZ A;  3EX8 A;  1DHF A;  5HSR A;  1DG8 A;  1RX3 A;  3JWK A;  3I8A X;  4QJZ D;  4ELG A;  3HJ3 A;  2XW7 A;  2DRC A;  4ELF A;  3QLW A;  4KJK A;  1DR3 A;  2W3M A;  1AOE A;  3QLS A;  3FQO A;  3OAF A;  4XT6 A;  4P3R A;  4XT8 A;  3CLB A;  1DAJ A;  2AZN A;  1RE7 A;  4IXF X;  3L3R A;  4DPD A;  1S3W A;  1KMV A;  4KAK A;  2OIP A;  2CD2 A;  3NXV A;  1ZDR A;  1LUD A;  3OCH A;  3JWM A;  1DHJ A;  3FRA X;  3NXX A;  4QLF A;  4KLX A;  4PTJ A;  5HF0 X;  4FGH A;  4PTH A;  3FQV A;  1RX9 A;  3TD8 A;  3NTZ A;  4Q0D A;  2BLA A;  3JSU A;  3GYF A;  1RX5 A;  3QYL A;  3KJR A;  4I1N A;  4NX6 A;  3QYO A;  3JWF A;  3K47 A;  3FY9 X;  2JYB A;  3FRE X;  3IRM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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