1KMSA

Human dihydrofolate reductase complexed with nadph and 6-([5-quinolylamino]methyl)-2,4-diamino-5-methylpyrido[2,3-d]pyrimidine (sri-9439), a lipophilic antifolate
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
184
structure length
184
Chain Sequence
SLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 55
structure length 184
sequence length 184
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2001-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1kmsA00
3NXRA 3JW5A 5HVBA 1M7AA 3QLZA 5JA3A 5HSRA 4OSGA 5HSUA 1IA3A 1DIUA 2DRCA 4G8ZX 2FZIA 4XT5A 3CLBA 3K47A 3F0UX 3QYLA 4IXFX 3IRNA 1KMSA 3TQAA 3TQ8A 1DRBA 1E26A 1TDRA 4LAEX 3I8AX 3F0BX 5ECCA 4X5HA 1DDRA 3K74A 6DFRA 4H95A 3INVA 3E0BA 3KJRA 3EX8A 3NU0A 5DXVA 5HQZA 1RA9A 4P68A 5HF0X 2ANOA 3KFYA 3K2HA 4M2XA 3NXVA 1RX1A 4Q67A 1BOZA 4LEKX 1RA1A 4PTHA 3RG9A 4TU5X 3SRRX 4ELHA 4XE6X 1RA2A 1RX7A 4XT8A 1DRHA 2HXVA 3NZ6X 5HT4A 4DFRA 3NZCX 1S3UA 2C2TA 1DDSA 1HFPA 3DG8A 4Q0EA 4QI9A 4I13A 4KFJA 4CD2A 3IRMA 3S9UA 4H97A 3F0SX 3FYWX 3FQ0A 2OBCA 4QHVA 5DFRA 3FRFX 4GH8A 2W9HA 1RX9A 3QFXA 3OCHA 2W3VA 3HBBA 3DFRA 1DR2A 3QL0A 4LAGX 2OIPA 3D80A 3Q1HA 3NXXA 3TD8A 3FREX 1PDBA 3GYFA 1RH3A 2GD9A 3JW3A 5ECXA 1J3JA 3SRWX 3JWMA 1KLKA 1DG8A 2G6VA 3UM6A 3LG4A 3SA1A 1AI9A 3N0HA 4KLXA 3JVXA 1MVTA 3GI2A 4PSSA 1DR4A 4QJZD 1RA3A 4LAHX 4P3QA 4ELGA 4X5GA 2W3BA 1RB2A 1LY4A 3SRQX 2B3ZA 1DRAA 3SH2A 4M6JA 3SA2A 3JWCA 5HQYA 1DHFA 2DHFA 1JOLA 4H98A 4FHBA 1DYRA 1DRFA 3FY8X 3NZBX 5CC9A 3FQOA 2P4GA 2C2SA 4KM0A 3JWKA 3QLWA 2W3WA 5FDAA 1DAJA 4G95A 3QGTA 3DATA 4XT6A 3NXYA 2ANQA 1RA8A 1RX4A 1JUVA 4QLGA 4XT4A 1DHIA 5CCCA 1SEJA 1LUDA 1AO8A 1MVSA 3NZ9X 3CSEA 4EJ1A 3EIGA 3SRSX 4HA7A 1RX3A 3QYOA 1U72A 4QLEA 4ELFA 4IXED 3JSUA 1RX8A 4PSTA 2ZZAA 4P66A 3I3RA 3ZPGA 3SQYX 1QZFA 3EEMA 7DFRA 4H96A 2H2QA 3CL9A 3R33A 4M7UA 4KAKA 1DR6A 3QG2A 2W9GA 1BZFA 3FY9X 1CZ3A 3SRUX 3FRBX 3FRAX 3ZPCA 1JOMA 3KGYA 2FZJA 4PTJA 3D84X 3NRRA 4KM2A 4DDRA 3FQCA 4Q0DA 4DPDA 4KEBA 3UM5A 3TQBA 1DR1A 2BL9A 1ZDRA 3EELA 1M78A 4ELBA 5E8QA 3NXTA 1VDRA 2W3MA 1DISA 1KMVA 1DF7A 2BLCA 3DRCA 3L3RA 1PD9A 4OR7A 2W9TA 3F8ZA 3QLXA 3DL6A 4M6KA 3SR5X 1J3IA 3CD2A 4KYAA 2LF1A 4ELEA 2XW7A 4PDJA 1IA4A 1DG5A 3FL8A 3K45A 1OHKA 2AZNA 4XECX 2W3AA 3IX9A 2JYBA 4KNEA 2KGKA 4HA9A 3DGAA 1RB3A 4DPHA 2BLAA 5JG0X 3SAIA 4KD7A 3ROAA 4HOGA 3F0VX 1DLRA 2HM9A 4X5JA 3QLSA 5U26A 3IA5A 4ECKA 3GHWA 3FL9A 4HOFA 4KY4A 2ITHA 3QL3A 5HUIA 3VCOA 4EILA 3KY8A 3QLRA 1LY3A 2D5NA 3FQVA 1D1GA 1OHJA 3EEKA 1J3KA 4KJLA 2CD2A 5HF2X 4DP3A 4X5FA 3S7AA 4M6LA 8DFRA 3FQZA 2BLBA 3GHCA 3M08A 4G3MA 4XT7A 3OAFA 1RF7A 1HFRA 4KY8A 3TQ9A 3F0XX 3EEJA 3NXOA 1RX6A 3NZDA 4FGGA 1DR3A 2O7PA 3F91A 3IROA 3UM8A 5HI6A 1S3VA 2L28A 3SGYA 1RX5A 1HFQA 1U70A 3RO9A 4P3RA 4EIGA 4Q6AA 3FYVX 1U71A 4KJKA 2QK8A 4NX7A 4KBNA 1M79A 3HJ3A 2FZHA 2INQA 1IA1A 4M7VA 5HPBA 4EIZA 3FRDX 4KJJA 2CIGA 5HT5A 3S3VA 3DAUA 1RX2A 1S3YA 5U27A 3GHVA 2HQPA 1AOEA 4PSYA 1IA2A 1YHOA 4NX6A 1RC4A 1DG7A 4QLFA 1RD7A 4RGCA 4QJCA 1CD2A 4KL9A 3DL5A 5EAJA 3NZAX 3IA4A 3FS6A 1DYHA 1DR7A 3F8YA 2W9SA 1S3WA 2D0KA 3KJSA 3JTWA 5HVEA 1DYJA 3NTZA 1DREA 1RE7A 3F0QX 1DR5A 4HOEA 4FGHA 4X5IA 3JWFA 1PD8A 3QLYA 1VJ3A 3M09A 1DLSA 4IXGX 4I1NA 3FQFA 1DYIA 1DHJA 4XRBA 1RG7A
chains in the Genus database with same CATH superfamily
3NXRA 3JW5A 5HVBA 1M7AA 3QLZA 5JA3A 5HSRA 4OSGA 5HSUA 1IA3A 1DIUA 2DRCA 4G8ZX 2FZIA 4XT5A 3CLBA 3K47A 3F0UX 3QYLA 4IXFX 3IRNA 1KMSA 3TQAA 3TQ8A 1DRBA 1E26A 1TDRA 4LAEX 3I8AX 3F0BX 5ECCA 4X5HA 1DDRA 3K74A 6DFRA 4H95A 3INVA 3E0BA 3KJRA 3EX8A 3NU0A 5DXVA 5HQZA 1RA9A 4P68A 5HF0X 2ANOA 3KFYA 3K2HA 4M2XA 3NXVA 1RX1A 4Q67A 1BOZA 4LEKX 1RA1A 4PTHA 3RG9A 4TU5X 3SRRX 4ELHA 4XE6X 1RA2A 1RX7A 4XT8A 1DRHA 2HXVA 3NZ6X 5HT4A 4DFRA 3NZCX 1S3UA 2C2TA 1DDSA 1HFPA 3DG8A 4Q0EA 4QI9A 4I13A 4KFJA 4CD2A 3IRMA 3S9UA 4H97A 3F0SX 3FYWX 3FQ0A 2OBCA 4QHVA 5DFRA 3FRFX 4GH8A 2W9HA 1RX9A 3QFXA 3OCHA 2W3VA 3HBBA 3DFRA 1DR2A 3QL0A 4LAGX 2OIPA 3D80A 3Q1HA 3NXXA 3TD8A 3FREX 1PDBA 3GYFA 1RH3A 2GD9A 3JW3A 5ECXA 1J3JA 3SRWX 3JWMA 1KLKA 1DG8A 2G6VA 3UM6A 3LG4A 3SA1A 1AI9A 3N0HA 4KLXA 3JVXA 1MVTA 3GI2A 4PSSA 1DR4A 4QJZD 1RA3A 4LAHX 4P3QA 4ELGA 4X5GA 2W3BA 1RB2A 1LY4A 3SRQX 2B3ZA 1DRAA 3SH2A 4M6JA 3SA2A 3JWCA 5HQYA 1DHFA 2DHFA 1JOLA 4H98A 4FHBA 1DYRA 1DRFA 3FY8X 3NZBX 5CC9A 3FQOA 2P4GA 2C2SA 4KM0A 3JWKA 3QLWA 2W3WA 5FDAA 1DAJA 4G95A 3QGTA 3DATA 4XT6A 3NXYA 2ANQA 1RA8A 1RX4A 1JUVA 4QLGA 4XT4A 1DHIA 5CCCA 1SEJA 1LUDA 1AO8A 1MVSA 3NZ9X 3CSEA 4EJ1A 3EIGA 3SRSX 4HA7A 1RX3A 3QYOA 1U72A 4QLEA 4ELFA 4IXED 3JSUA 1RX8A 4PSTA 2ZZAA 4P66A 3I3RA 3ZPGA 3SQYX 1QZFA 3EEMA 7DFRA 4H96A 2H2QA 3CL9A 3R33A 4M7UA 4KAKA 1DR6A 3QG2A 2W9GA 1BZFA 3FY9X 1CZ3A 3SRUX 3FRBX 3FRAX 3ZPCA 1JOMA 3KGYA 2FZJA 4PTJA 3D84X 3NRRA 4KM2A 4DDRA 3FQCA 4Q0DA 4DPDA 4KEBA 3UM5A 3TQBA 1DR1A 2BL9A 1ZDRA 3EELA 1M78A 4ELBA 5E8QA 3NXTA 1VDRA 2W3MA 1DISA 1KMVA 1DF7A 2BLCA 3DRCA 3L3RA 1PD9A 4OR7A 2W9TA 3F8ZA 3QLXA 3DL6A 4M6KA 3SR5X 1J3IA 3CD2A 4KYAA 2LF1A 4ELEA 2XW7A 4PDJA 1IA4A 1DG5A 3FL8A 3K45A 1OHKA 2AZNA 4XECX 2W3AA 3IX9A 2JYBA 4KNEA 2KGKA 4HA9A 3DGAA 1RB3A 4DPHA 2BLAA 5JG0X 3SAIA 4KD7A 3ROAA 4HOGA 3F0VX 1DLRA 2HM9A 4X5JA 3QLSA 5U26A 3IA5A 4ECKA 3GHWA 3FL9A 4HOFA 4KY4A 2ITHA 3QL3A 5HUIA 3VCOA 4EILA 3KY8A 3QLRA 1LY3A 2D5NA 3FQVA 1D1GA 1OHJA 3EEKA 1J3KA 4KJLA 2CD2A 5HF2X 4DP3A 4X5FA 3S7AA 4M6LA 8DFRA 3FQZA 2BLBA 3GHCA 3M08A 4G3MA 4XT7A 3OAFA 1RF7A 1HFRA 4KY8A 3TQ9A 3F0XX 3EEJA 3NXOA 1RX6A 3NZDA 4FGGA 1DR3A 2O7PA 3F91A 3IROA 3UM8A 5HI6A 1S3VA 2L28A 3SGYA 1RX5A 1HFQA 1U70A 3RO9A 4P3RA 4EIGA 4Q6AA 3FYVX 1U71A 4KJKA 2QK8A 4NX7A 4KBNA 1M79A 3HJ3A 2FZHA 2INQA 1IA1A 4M7VA 5HPBA 4EIZA 3FRDX 4KJJA 2CIGA 5HT5A 3S3VA 3DAUA 1RX2A 1S3YA 5U27A 3GHVA 2HQPA 1AOEA 4PSYA 1IA2A 1YHOA 4NX6A 1RC4A 1DG7A 4QLFA 1RD7A 4RGCA 4QJCA 1CD2A 4KL9A 3DL5A 5EAJA 3NZAX 3IA4A 3FS6A 1DYHA 1DR7A 3F8YA 2W9SA 1S3WA 2D0KA 3KJSA 3JTWA 5HVEA 1DYJA 3NTZA 1DREA 1RE7A 3F0QX 1DR5A 4HOEA 4FGHA 4X5IA 3JWFA 1PD8A 3QLYA 1VJ3A 3M09A 1DLSA 4IXGX 4I1NA 3FQFA 1DYIA 1DHJA 4XRBA 1RG7A
chains in the Genus database with same CATH topology
3NXRA 3JW5A 5HVBA 1M7AA 3QLZA 5JA3A 5HSRA 4OSGA 5HSUA 1IA3A 1DIUA 2DRCA 4G8ZX 2FZIA 4XT5A 3CLBA 3K47A 3F0UX 3QYLA 4IXFX 3IRNA 1KMSA 3TQAA 3TQ8A 1DRBA 1E26A 1TDRA 4LAEX 3I8AX 3F0BX 5ECCA 4X5HA 1DDRA 3K74A 6DFRA 4H95A 3INVA 3E0BA 3KJRA 3EX8A 3NU0A 5DXVA 5HQZA 1RA9A 4P68A 5HF0X 2ANOA 3KFYA 3K2HA 4M2XA 3NXVA 1RX1A 4Q67A 1BOZA 4LEKX 1RA1A 4PTHA 3RG9A 4TU5X 3SRRX 4ELHA 4XE6X 1RA2A 1RX7A 4XT8A 1DRHA 2HXVA 3NZ6X 5HT4A 4DFRA 3NZCX 1S3UA 2C2TA 1DDSA 1HFPA 3DG8A 4Q0EA 4QI9A 4I13A 4KFJA 4CD2A 3IRMA 3S9UA 4H97A 3F0SX 3FYWX 3FQ0A 2OBCA 4QHVA 5DFRA 3FRFX 4GH8A 2W9HA 1RX9A 3QFXA 3OCHA 2W3VA 3HBBA 3DFRA 1DR2A 3QL0A 4LAGX 2OIPA 3D80A 3Q1HA 3NXXA 3TD8A 3FREX 1PDBA 3GYFA 1RH3A 2GD9A 3JW3A 5ECXA 1J3JA 3SRWX 3JWMA 1KLKA 1DG8A 2G6VA 3UM6A 3LG4A 3SA1A 1AI9A 3N0HA 4KLXA 3JVXA 1MVTA 3GI2A 4PSSA 1DR4A 4QJZD 1RA3A 4LAHX 4P3QA 4ELGA 4X5GA 2W3BA 1RB2A 1LY4A 3SRQX 2B3ZA 1DRAA 3SH2A 4M6JA 3SA2A 3JWCA 5HQYA 1DHFA 2DHFA 1JOLA 4H98A 4FHBA 1DYRA 1DRFA 3FY8X 3NZBX 5CC9A 3FQOA 2P4GA 2C2SA 4KM0A 3JWKA 3QLWA 2W3WA 5FDAA 1DAJA 4G95A 3QGTA 3DATA 4XT6A 3NXYA 2ANQA 1RA8A 1RX4A 1JUVA 4QLGA 4XT4A 1DHIA 5CCCA 1SEJA 1LUDA 1AO8A 1MVSA 3NZ9X 3CSEA 4EJ1A 3EIGA 3SRSX 4HA7A 1RX3A 3QYOA 1U72A 4QLEA 4ELFA 4IXED 3JSUA 1RX8A 4PSTA 2ZZAA 4P66A 3I3RA 3ZPGA 3SQYX 1QZFA 3EEMA 7DFRA 4H96A 2H2QA 3CL9A 3R33A 4M7UA 4KAKA 1DR6A 3QG2A 2W9GA 1BZFA 3FY9X 1CZ3A 3SRUX 3FRBX 3FRAX 3ZPCA 1JOMA 3KGYA 2FZJA 4PTJA 3D84X 3NRRA 4KM2A 4DDRA 3FQCA 4Q0DA 4DPDA 4KEBA 3UM5A 3TQBA 1DR1A 2BL9A 1ZDRA 3EELA 1M78A 4ELBA 5E8QA 3NXTA 1VDRA 2W3MA 1DISA 1KMVA 1DF7A 2BLCA 3DRCA 3L3RA 1PD9A 4OR7A 2W9TA 3F8ZA 3QLXA 3DL6A 4M6KA 3SR5X 1J3IA 3CD2A 4KYAA 2LF1A 4ELEA 2XW7A 4PDJA 1IA4A 1DG5A 3FL8A 3K45A 1OHKA 2AZNA 4XECX 2W3AA 3IX9A 2JYBA 4KNEA 2KGKA 4HA9A 3DGAA 1RB3A 4DPHA 2BLAA 5JG0X 3SAIA 4KD7A 3ROAA 4HOGA 3F0VX 1DLRA 2HM9A 4X5JA 3QLSA 5U26A 3IA5A 4ECKA 3GHWA 3FL9A 4HOFA 4KY4A 2ITHA 3QL3A 5HUIA 3VCOA 4EILA 3KY8A 3QLRA 1LY3A 2D5NA 3FQVA 1D1GA 1OHJA 3EEKA 1J3KA 4KJLA 2CD2A 5HF2X 4DP3A 4X5FA 3S7AA 4M6LA 8DFRA 3FQZA 2BLBA 3GHCA 3M08A 4G3MA 4XT7A 3OAFA 1RF7A 1HFRA 4KY8A 3TQ9A 3F0XX 3EEJA 3NXOA 1RX6A 3NZDA 4FGGA 1DR3A 2O7PA 3F91A 3IROA 3UM8A 5HI6A 1S3VA 2L28A 3SGYA 1RX5A 1HFQA 1U70A 3RO9A 4P3RA 4EIGA 4Q6AA 3FYVX 1U71A 4KJKA 2QK8A 4NX7A 4KBNA 1M79A 3HJ3A 2FZHA 2INQA 1IA1A 4M7VA 5HPBA 4EIZA 3FRDX 4KJJA 2CIGA 5HT5A 3S3VA 3DAUA 1RX2A 1S3YA 5U27A 3GHVA 2HQPA 1AOEA 4PSYA 1IA2A 1YHOA 4NX6A 1RC4A 1DG7A 4QLFA 1RD7A 4RGCA 4QJCA 1CD2A 4KL9A 3DL5A 5EAJA 3NZAX 3IA4A 3FS6A 1DYHA 1DR7A 3F8YA 2W9SA 1S3WA 2D0KA 3KJSA 3JTWA 5HVEA 1DYJA 3NTZA 1DREA 1RE7A 3F0QX 1DR5A 4HOEA 4FGHA 4X5IA 3JWFA 1PD8A 3QLYA 1VJ3A 3M09A 1DLSA 4IXGX 4I1NA 3FQFA 1DYIA 1DHJA 4XRBA 1RG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NXR A;  3JW5 A;  5HVB A;  1M7A A;  3QLZ A;  5JA3 A;  5HSR A;  4OSG A;  5HSU A;  1IA3 A;  1DIU A;  2DRC A;  4G8Z X;  2FZI A;  4XT5 A;  3CLB A;  3K47 A;  3F0U X;  3QYL A;  4IXF X;  3IRN A;  1KMS A;  3TQA A;  3TQ8 A;  1DRB A;  1E26 A;  1TDR A;  4LAE X;  3I8A X;  3F0B X;  5ECC A;  4X5H A;  1DDR A;  3K74 A;  6DFR A;  4H95 A;  3INV A;  3E0B A;  3KJR A;  3EX8 A;  3NU0 A;  5DXV A;  5HQZ A;  1RA9 A;  4P68 A;  5HF0 X;  2ANO A;  3KFY A;  3K2H A;  4M2X A;  3NXV A;  1RX1 A;  4Q67 A;  1BOZ A;  4LEK X;  1RA1 A;  4PTH A;  3RG9 A;  4TU5 X;  3SRR X;  4ELH A;  4XE6 X;  1RA2 A;  1RX7 A;  4XT8 A;  1DRH A;  2HXV A;  3NZ6 X;  5HT4 A;  4DFR A;  3NZC X;  1S3U A;  2C2T A;  1DDS A;  1HFP A;  3DG8 A;  4Q0E A;  4QI9 A;  4I13 A;  4KFJ A;  4CD2 A;  3IRM A;  3S9U A;  4H97 A;  3F0S X;  3FYW X;  3FQ0 A;  2OBC A;  4QHV A;  5DFR A;  3FRF X;  4GH8 A;  2W9H A;  1RX9 A;  3QFX A;  3OCH A;  2W3V A;  3HBB A;  3DFR A;  1DR2 A;  3QL0 A;  4LAG X;  2OIP A;  3D80 A;  3Q1H A;  3NXX A;  3TD8 A;  3FRE X;  1PDB A;  3GYF A;  1RH3 A;  2GD9 A;  3JW3 A;  5ECX A;  1J3J A;  3SRW X;  3JWM A;  1KLK A;  1DG8 A;  2G6V A;  3UM6 A;  3LG4 A;  3SA1 A;  1AI9 A;  3N0H A;  4KLX A;  3JVX A;  1MVT A;  3GI2 A;  4PSS A;  1DR4 A;  4QJZ D;  1RA3 A;  4LAH X;  4P3Q A;  4ELG A;  4X5G A;  2W3B A;  1RB2 A;  1LY4 A;  3SRQ X;  2B3Z A;  1DRA A;  3SH2 A;  4M6J A;  3SA2 A;  3JWC A;  5HQY A;  1DHF A;  2DHF A;  1JOL A;  4H98 A;  4FHB A;  1DYR A;  1DRF A;  3FY8 X;  3NZB X;  5CC9 A;  3FQO A;  2P4G A;  2C2S A;  4KM0 A;  3JWK A;  3QLW A;  2W3W A;  5FDA A;  1DAJ A;  4G95 A;  3QGT A;  3DAT A;  4XT6 A;  3NXY A;  2ANQ A;  1RA8 A;  1RX4 A;  1JUV A;  4QLG A;  4XT4 A;  1DHI A;  5CCC A;  1SEJ A;  1LUD A;  1AO8 A;  1MVS A;  3NZ9 X;  3CSE A;  4EJ1 A;  3EIG A;  3SRS X;  4HA7 A;  1RX3 A;  3QYO A;  1U72 A;  4QLE A;  4ELF A;  4IXE D;  3JSU A;  1RX8 A;  4PST A;  2ZZA A;  4P66 A;  3I3R A;  3ZPG A;  3SQY X;  1QZF A;  3EEM A;  7DFR A;  4H96 A;  2H2Q A;  3CL9 A;  3R33 A;  4M7U A;  4KAK A;  1DR6 A;  3QG2 A;  2W9G A;  1BZF A;  3FY9 X;  1CZ3 A;  3SRU X;  3FRB X;  3FRA X;  3ZPC A;  1JOM A;  3KGY A;  2FZJ A;  4PTJ A;  3D84 X;  3NRR A;  4KM2 A;  4DDR A;  3FQC A;  4Q0D A;  4DPD A;  4KEB A;  3UM5 A;  3TQB A;  1DR1 A;  2BL9 A;  1ZDR A;  3EEL A;  1M78 A;  4ELB A;  5E8Q A;  3NXT A;  1VDR A;  2W3M A;  1DIS A;  1KMV A;  1DF7 A;  2BLC A;  3DRC A;  3L3R A;  1PD9 A;  4OR7 A;  2W9T A;  3F8Z A;  3QLX A;  3DL6 A;  4M6K A;  3SR5 X;  1J3I A;  3CD2 A;  4KYA A;  2LF1 A;  4ELE A;  2XW7 A;  4PDJ A;  1IA4 A;  1DG5 A;  3FL8 A;  3K45 A;  1OHK A;  2AZN A;  4XEC X;  2W3A A;  3IX9 A;  2JYB A;  4KNE A;  2KGK A;  4HA9 A;  3DGA A;  1RB3 A;  4DPH A;  2BLA A;  5JG0 X;  3SAI A;  4KD7 A;  3ROA A;  4HOG A;  3F0V X;  1DLR A;  2HM9 A;  4X5J A;  3QLS A;  5U26 A;  3IA5 A;  4ECK A;  3GHW A;  3FL9 A;  4HOF A;  4KY4 A;  2ITH A;  3QL3 A;  5HUI A;  3VCO A;  4EIL A;  3KY8 A;  3QLR A;  1LY3 A;  2D5N A;  3FQV A;  1D1G A;  1OHJ A;  3EEK A;  1J3K A;  4KJL A;  2CD2 A;  5HF2 X;  4DP3 A;  4X5F A;  3S7A A;  4M6L A;  8DFR A;  3FQZ A;  2BLB A;  3GHC A;  3M08 A;  4G3M A;  4XT7 A;  3OAF A;  1RF7 A;  1HFR A;  4KY8 A;  3TQ9 A;  3F0X X;  3EEJ A;  3NXO A;  1RX6 A;  3NZD A;  4FGG A;  1DR3 A;  2O7P A;  3F91 A;  3IRO A;  3UM8 A;  5HI6 A;  1S3V A;  2L28 A;  3SGY A;  1RX5 A;  1HFQ A;  1U70 A;  3RO9 A;  4P3R A;  4EIG A;  4Q6A A;  3FYV X;  1U71 A;  4KJK A;  2QK8 A;  4NX7 A;  4KBN A;  1M79 A;  3HJ3 A;  2FZH A;  2INQ A;  1IA1 A;  4M7V A;  5HPB A;  4EIZ A;  3FRD X;  4KJJ A;  2CIG A;  5HT5 A;  3S3V A;  3DAU A;  1RX2 A;  1S3Y A;  5U27 A;  3GHV A;  2HQP A;  1AOE A;  4PSY A;  1IA2 A;  1YHO A;  4NX6 A;  1RC4 A;  1DG7 A;  4QLF A;  1RD7 A;  4RGC A;  4QJC A;  1CD2 A;  4KL9 A;  3DL5 A;  5EAJ A;  3NZA X;  3IA4 A;  3FS6 A;  1DYH A;  1DR7 A;  3F8Y A;  2W9S A;  1S3W A;  2D0K A;  3KJS A;  3JTW A;  5HVE A;  1DYJ A;  3NTZ A;  1DRE A;  1RE7 A;  3F0Q X;  1DR5 A;  4HOE A;  4FGH A;  4X5I A;  3JWF A;  1PD8 A;  3QLY A;  1VJ3 A;  3M09 A;  1DLS A;  4IXG X;  4I1N A;  3FQF A;  1DYI A;  1DHJ A;  4XRB A;  1RG7 A; 
#chains in the Genus database with same CATH topology
 3NXR A;  3JW5 A;  5HVB A;  1M7A A;  3QLZ A;  5JA3 A;  5HSR A;  4OSG A;  5HSU A;  1IA3 A;  1DIU A;  2DRC A;  4G8Z X;  2FZI A;  4XT5 A;  3CLB A;  3K47 A;  3F0U X;  3QYL A;  4IXF X;  3IRN A;  1KMS A;  3TQA A;  3TQ8 A;  1DRB A;  1E26 A;  1TDR A;  4LAE X;  3I8A X;  3F0B X;  5ECC A;  4X5H A;  1DDR A;  3K74 A;  6DFR A;  4H95 A;  3INV A;  3E0B A;  3KJR A;  3EX8 A;  3NU0 A;  5DXV A;  5HQZ A;  1RA9 A;  4P68 A;  5HF0 X;  2ANO A;  3KFY A;  3K2H A;  4M2X A;  3NXV A;  1RX1 A;  4Q67 A;  1BOZ A;  4LEK X;  1RA1 A;  4PTH A;  3RG9 A;  4TU5 X;  3SRR X;  4ELH A;  4XE6 X;  1RA2 A;  1RX7 A;  4XT8 A;  1DRH A;  2HXV A;  3NZ6 X;  5HT4 A;  4DFR A;  3NZC X;  1S3U A;  2C2T A;  1DDS A;  1HFP A;  3DG8 A;  4Q0E A;  4QI9 A;  4I13 A;  4KFJ A;  4CD2 A;  3IRM A;  3S9U A;  4H97 A;  3F0S X;  3FYW X;  3FQ0 A;  2OBC A;  4QHV A;  5DFR A;  3FRF X;  4GH8 A;  2W9H A;  1RX9 A;  3QFX A;  3OCH A;  2W3V A;  3HBB A;  3DFR A;  1DR2 A;  3QL0 A;  4LAG X;  2OIP A;  3D80 A;  3Q1H A;  3NXX A;  3TD8 A;  3FRE X;  1PDB A;  3GYF A;  1RH3 A;  2GD9 A;  3JW3 A;  5ECX A;  1J3J A;  3SRW X;  3JWM A;  1KLK A;  1DG8 A;  2G6V A;  3UM6 A;  3LG4 A;  3SA1 A;  1AI9 A;  3N0H A;  4KLX A;  3JVX A;  1MVT A;  3GI2 A;  4PSS A;  1DR4 A;  4QJZ D;  1RA3 A;  4LAH X;  4P3Q A;  4ELG A;  4X5G A;  2W3B A;  1RB2 A;  1LY4 A;  3SRQ X;  2B3Z A;  1DRA A;  3SH2 A;  4M6J A;  3SA2 A;  3JWC A;  5HQY A;  1DHF A;  2DHF A;  1JOL A;  4H98 A;  4FHB A;  1DYR A;  1DRF A;  3FY8 X;  3NZB X;  5CC9 A;  3FQO A;  2P4G A;  2C2S A;  4KM0 A;  3JWK A;  3QLW A;  2W3W A;  5FDA A;  1DAJ A;  4G95 A;  3QGT A;  3DAT A;  4XT6 A;  3NXY A;  2ANQ A;  1RA8 A;  1RX4 A;  1JUV A;  4QLG A;  4XT4 A;  1DHI A;  5CCC A;  1SEJ A;  1LUD A;  1AO8 A;  1MVS A;  3NZ9 X;  3CSE A;  4EJ1 A;  3EIG A;  3SRS X;  4HA7 A;  1RX3 A;  3QYO A;  1U72 A;  4QLE A;  4ELF A;  4IXE D;  3JSU A;  1RX8 A;  4PST A;  2ZZA A;  4P66 A;  3I3R A;  3ZPG A;  3SQY X;  1QZF A;  3EEM A;  7DFR A;  4H96 A;  2H2Q A;  3CL9 A;  3R33 A;  4M7U A;  4KAK A;  1DR6 A;  3QG2 A;  2W9G A;  1BZF A;  3FY9 X;  1CZ3 A;  3SRU X;  3FRB X;  3FRA X;  3ZPC A;  1JOM A;  3KGY A;  2FZJ A;  4PTJ A;  3D84 X;  3NRR A;  4KM2 A;  4DDR A;  3FQC A;  4Q0D A;  4DPD A;  4KEB A;  3UM5 A;  3TQB A;  1DR1 A;  2BL9 A;  1ZDR A;  3EEL A;  1M78 A;  4ELB A;  5E8Q A;  3NXT A;  1VDR A;  2W3M A;  1DIS A;  1KMV A;  1DF7 A;  2BLC A;  3DRC A;  3L3R A;  1PD9 A;  4OR7 A;  2W9T A;  3F8Z A;  3QLX A;  3DL6 A;  4M6K A;  3SR5 X;  1J3I A;  3CD2 A;  4KYA A;  2LF1 A;  4ELE A;  2XW7 A;  4PDJ A;  1IA4 A;  1DG5 A;  3FL8 A;  3K45 A;  1OHK A;  2AZN A;  4XEC X;  2W3A A;  3IX9 A;  2JYB A;  4KNE A;  2KGK A;  4HA9 A;  3DGA A;  1RB3 A;  4DPH A;  2BLA A;  5JG0 X;  3SAI A;  4KD7 A;  3ROA A;  4HOG A;  3F0V X;  1DLR A;  2HM9 A;  4X5J A;  3QLS A;  5U26 A;  3IA5 A;  4ECK A;  3GHW A;  3FL9 A;  4HOF A;  4KY4 A;  2ITH A;  3QL3 A;  5HUI A;  3VCO A;  4EIL A;  3KY8 A;  3QLR A;  1LY3 A;  2D5N A;  3FQV A;  1D1G A;  1OHJ A;  3EEK A;  1J3K A;  4KJL A;  2CD2 A;  5HF2 X;  4DP3 A;  4X5F A;  3S7A A;  4M6L A;  8DFR A;  3FQZ A;  2BLB A;  3GHC A;  3M08 A;  4G3M A;  4XT7 A;  3OAF A;  1RF7 A;  1HFR A;  4KY8 A;  3TQ9 A;  3F0X X;  3EEJ A;  3NXO A;  1RX6 A;  3NZD A;  4FGG A;  1DR3 A;  2O7P A;  3F91 A;  3IRO A;  3UM8 A;  5HI6 A;  1S3V A;  2L28 A;  3SGY A;  1RX5 A;  1HFQ A;  1U70 A;  3RO9 A;  4P3R A;  4EIG A;  4Q6A A;  3FYV X;  1U71 A;  4KJK A;  2QK8 A;  4NX7 A;  4KBN A;  1M79 A;  3HJ3 A;  2FZH A;  2INQ A;  1IA1 A;  4M7V A;  5HPB A;  4EIZ A;  3FRD X;  4KJJ A;  2CIG A;  5HT5 A;  3S3V A;  3DAU A;  1RX2 A;  1S3Y A;  5U27 A;  3GHV A;  2HQP A;  1AOE A;  4PSY A;  1IA2 A;  1YHO A;  4NX6 A;  1RC4 A;  1DG7 A;  4QLF A;  1RD7 A;  4RGC A;  4QJC A;  1CD2 A;  4KL9 A;  3DL5 A;  5EAJ A;  3NZA X;  3IA4 A;  3FS6 A;  1DYH A;  1DR7 A;  3F8Y A;  2W9S A;  1S3W A;  2D0K A;  3KJS A;  3JTW A;  5HVE A;  1DYJ A;  3NTZ A;  1DRE A;  1RE7 A;  3F0Q X;  1DR5 A;  4HOE A;  4FGH A;  4X5I A;  3JWF A;  1PD8 A;  3QLY A;  1VJ3 A;  3M09 A;  1DLS A;  4IXG X;  4I1N A;  3FQF A;  1DYI A;  1DHJ A;  4XRB A;  1RG7 A; 
#chains in the Genus database with same CATH homology
 3NXR A;  3JW5 A;  5HVB A;  1M7A A;  3QLZ A;  5JA3 A;  5HSR A;  4OSG A;  5HSU A;  1IA3 A;  1DIU A;  2DRC A;  4G8Z X;  2FZI A;  4XT5 A;  3CLB A;  3K47 A;  3F0U X;  3QYL A;  4IXF X;  3IRN A;  1KMS A;  3TQA A;  3TQ8 A;  1DRB A;  1E26 A;  1TDR A;  4LAE X;  3I8A X;  3F0B X;  5ECC A;  4X5H A;  1DDR A;  3K74 A;  6DFR A;  4H95 A;  3INV A;  3E0B A;  3KJR A;  3EX8 A;  3NU0 A;  5DXV A;  5HQZ A;  1RA9 A;  4P68 A;  5HF0 X;  2ANO A;  3KFY A;  3K2H A;  4M2X A;  3NXV A;  1RX1 A;  4Q67 A;  1BOZ A;  4LEK X;  1RA1 A;  4PTH A;  3RG9 A;  4TU5 X;  3SRR X;  4ELH A;  4XE6 X;  1RA2 A;  1RX7 A;  4XT8 A;  1DRH A;  2HXV A;  3NZ6 X;  5HT4 A;  4DFR A;  3NZC X;  1S3U A;  2C2T A;  1DDS A;  1HFP A;  3DG8 A;  4Q0E A;  4QI9 A;  4I13 A;  4KFJ A;  4CD2 A;  3IRM A;  3S9U A;  4H97 A;  3F0S X;  3FYW X;  3FQ0 A;  2OBC A;  4QHV A;  5DFR A;  3FRF X;  4GH8 A;  2W9H A;  1RX9 A;  3QFX A;  3OCH A;  2W3V A;  3HBB A;  3DFR A;  1DR2 A;  3QL0 A;  4LAG X;  2OIP A;  3D80 A;  3Q1H A;  3NXX A;  3TD8 A;  3FRE X;  1PDB A;  3GYF A;  1RH3 A;  2GD9 A;  3JW3 A;  5ECX A;  1J3J A;  3SRW X;  3JWM A;  1KLK A;  1DG8 A;  2G6V A;  3UM6 A;  3LG4 A;  3SA1 A;  1AI9 A;  3N0H A;  4KLX A;  3JVX A;  1MVT A;  3GI2 A;  4PSS A;  1DR4 A;  4QJZ D;  1RA3 A;  4LAH X;  4P3Q A;  4ELG A;  4X5G A;  2W3B A;  1RB2 A;  1LY4 A;  3SRQ X;  2B3Z A;  1DRA A;  3SH2 A;  4M6J A;  3SA2 A;  3JWC A;  5HQY A;  1DHF A;  2DHF A;  1JOL A;  4H98 A;  4FHB A;  1DYR A;  1DRF A;  3FY8 X;  3NZB X;  5CC9 A;  3FQO A;  2P4G A;  2C2S A;  4KM0 A;  3JWK A;  3QLW A;  2W3W A;  5FDA A;  1DAJ A;  4G95 A;  3QGT A;  3DAT A;  4XT6 A;  3NXY A;  2ANQ A;  1RA8 A;  1RX4 A;  1JUV A;  4QLG A;  4XT4 A;  1DHI A;  5CCC A;  1SEJ A;  1LUD A;  1AO8 A;  1MVS A;  3NZ9 X;  3CSE A;  4EJ1 A;  3EIG A;  3SRS X;  4HA7 A;  1RX3 A;  3QYO A;  1U72 A;  4QLE A;  4ELF A;  4IXE D;  3JSU A;  1RX8 A;  4PST A;  2ZZA A;  4P66 A;  3I3R A;  3ZPG A;  3SQY X;  1QZF A;  3EEM A;  7DFR A;  4H96 A;  2H2Q A;  3CL9 A;  3R33 A;  4M7U A;  4KAK A;  1DR6 A;  3QG2 A;  2W9G A;  1BZF A;  3FY9 X;  1CZ3 A;  3SRU X;  3FRB X;  3FRA X;  3ZPC A;  1JOM A;  3KGY A;  2FZJ A;  4PTJ A;  3D84 X;  3NRR A;  4KM2 A;  4DDR A;  3FQC A;  4Q0D A;  4DPD A;  4KEB A;  3UM5 A;  3TQB A;  1DR1 A;  2BL9 A;  1ZDR A;  3EEL A;  1M78 A;  4ELB A;  5E8Q A;  3NXT A;  1VDR A;  2W3M A;  1DIS A;  1KMV A;  1DF7 A;  2BLC A;  3DRC A;  3L3R A;  1PD9 A;  4OR7 A;  2W9T A;  3F8Z A;  3QLX A;  3DL6 A;  4M6K A;  3SR5 X;  1J3I A;  3CD2 A;  4KYA A;  2LF1 A;  4ELE A;  2XW7 A;  4PDJ A;  1IA4 A;  1DG5 A;  3FL8 A;  3K45 A;  1OHK A;  2AZN A;  4XEC X;  2W3A A;  3IX9 A;  2JYB A;  4KNE A;  2KGK A;  4HA9 A;  3DGA A;  1RB3 A;  4DPH A;  2BLA A;  5JG0 X;  3SAI A;  4KD7 A;  3ROA A;  4HOG A;  3F0V X;  1DLR A;  2HM9 A;  4X5J A;  3QLS A;  5U26 A;  3IA5 A;  4ECK A;  3GHW A;  3FL9 A;  4HOF A;  4KY4 A;  2ITH A;  3QL3 A;  5HUI A;  3VCO A;  4EIL A;  3KY8 A;  3QLR A;  1LY3 A;  2D5N A;  3FQV A;  1D1G A;  1OHJ A;  3EEK A;  1J3K A;  4KJL A;  2CD2 A;  5HF2 X;  4DP3 A;  4X5F A;  3S7A A;  4M6L A;  8DFR A;  3FQZ A;  2BLB A;  3GHC A;  3M08 A;  4G3M A;  4XT7 A;  3OAF A;  1RF7 A;  1HFR A;  4KY8 A;  3TQ9 A;  3F0X X;  3EEJ A;  3NXO A;  1RX6 A;  3NZD A;  4FGG A;  1DR3 A;  2O7P A;  3F91 A;  3IRO A;  3UM8 A;  5HI6 A;  1S3V A;  2L28 A;  3SGY A;  1RX5 A;  1HFQ A;  1U70 A;  3RO9 A;  4P3R A;  4EIG A;  4Q6A A;  3FYV X;  1U71 A;  4KJK A;  2QK8 A;  4NX7 A;  4KBN A;  1M79 A;  3HJ3 A;  2FZH A;  2INQ A;  1IA1 A;  4M7V A;  5HPB A;  4EIZ A;  3FRD X;  4KJJ A;  2CIG A;  5HT5 A;  3S3V A;  3DAU A;  1RX2 A;  1S3Y A;  5U27 A;  3GHV A;  2HQP A;  1AOE A;  4PSY A;  1IA2 A;  1YHO A;  4NX6 A;  1RC4 A;  1DG7 A;  4QLF A;  1RD7 A;  4RGC A;  4QJC A;  1CD2 A;  4KL9 A;  3DL5 A;  5EAJ A;  3NZA X;  3IA4 A;  3FS6 A;  1DYH A;  1DR7 A;  3F8Y A;  2W9S A;  1S3W A;  2D0K A;  3KJS A;  3JTW A;  5HVE A;  1DYJ A;  3NTZ A;  1DRE A;  1RE7 A;  3F0Q X;  1DR5 A;  4HOE A;  4FGH A;  4X5I A;  3JWF A;  1PD8 A;  3QLY A;  1VJ3 A;  3M09 A;  1DLS A;  4IXG X;  4I1N A;  3FQF A;  1DYI A;  1DHJ A;  4XRB A;  1RG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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