1RA2A

Dihydrofolate reductase complexed with folate and nicotinamide adenine dinucleotide phosphate (oxidized form)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 42
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1ra2A00
3HJ3A 3NXVA 1KMSA 1RX3A 4H97A 3I8AX 3JTWA 3QYOA 1RD7A 3KFYA 3QLWA 4EJ1A 3F0BX 3JSUA 4ECKA 3JWMA 3UM8A 4KY4A 4IXGX 4M6JA 3SA1A 3QG2A 2HM9A 1OHKA 3KGYA 5HUIA 4HOFA 5U27A 1RX8A 4XT4A 1DR2A 3IA5A 1DDSA 2BLAA 3FRAX 3L3RA 3NZCX 1RE7A 2HXVA 3JWFA 3SRRX 2BLBA 3OAFA 5EAJA 3KJSA 3QLYA 4QLEA 4X5IA 1DDRA 1RX9A 3EELA 3QL3A 3R33A 3F8YA 1U72A 4M6KA 3KY8A 3IRMA 1DRHA 4KFJA 1RB3A 1J3IA 1DLRA 4KLXA 5HF2X 3CSEA 4PSYA 4XT8A 4QJCA 4G3MA 3QL0A 1QZFA 5HPBA 5HI6A 1RA9A 4ELBA 4M7VA 1JOMA 3DGAA 3GI2A 8DFRA 2L28A 3FYVX 2OIPA 4KNEA 3UM6A 3D80A 2D5NA 3JVXA 5ECXA 1DHJA 3E0BA 2ZZAA 3KJRA 5HT4A 3F8ZA 4NX7A 3I3RA 1RA2A 3TQ8A 4RGCA 3SA2A 5CCCA 4PTJA 2AZNA 3N0HA 1DR6A 3IA4A 3NZAX 4HOGA 3SQYX 3FQZA 5DFRA 3GHWA 1KLKA 1DISA 4P68A 4OSGA 1RX4A 4HA9A 2W3MA 1J3JA 3QFXA 5HF0X 3QLRA 2XW7A 3NU0A 1D1GA 5JA3A 3EEMA 4KJLA 1HFQA 4ELEA 2W9GA 4XE6X 3DRCA 1RA3A 3FL9A 3S7AA 1BOZA 1JOLA 1DRBA 1DLSA 1U70A 1DYJA 3DL5A 5HVEA 1DR4A 3FQVA 3IROA 4KY8A 3DL6A 4H95A 3NZBX 1DHIA 2P4GA 3JWKA 3JW5A 3ZPCA 1IA3A 4NX6A 1IA2A 2DHFA 2W3BA 1S3VA 1DYHA 5JG0X 3FY8X 4XT7A 4DDRA 3TQ9A 2QK8A 1HFPA 3F0UX 4DP3A 2W9SA 3SGYA 1AI9A 4EILA 4DFRA 5ECCA 5HT5A 3SH2A 3JWCA 5HQYA 1DRAA 1DR3A 1LUDA 3NXOA 3FQ0A 3NXYA 1M78A 1RG7A 1JUVA 4Q0EA 4ELGA 3GHVA 4KEBA 2ITHA 1VDRA 1TDRA 3FL8A 3FREX 4G95A 3F0SX 1DG7A 4X5HA 2W9HA 3S9UA 3FQFA 2DRCA 3NXTA 2D0KA 1CZ3A 3QLZA 3DG8A 1DYRA 4M7UA 1AOEA 5E8QA 1SEJA 3TQBA 4IXFX 2HQPA 1M79A 3GYFA 3VCOA 3OCHA 1MVTA 2ANOA 2GD9A 3QYLA 3FQCA 1LY4A 4FHBA 4KL9A 3RO9A 1U71A 1S3YA 1DIUA 4M6LA 3F91A 4PSSA 4LAHX 2JYBA 5DXVA 7DFRA 4HOEA 1DRFA 1S3WA 5HQZA 3RG9A 4LAEX 3SRSX 2KGKA 1E26A 3GHCA 4PTHA 3D84X 1S3UA 2LF1A 1KMVA 1OHJA 3FRBX 2BL9A 3QLXA 3CLBA 5HSUA 2BLCA 4Q0DA 4H98A 3SR5X 1BZFA 2W3WA 4KJJA 1CD2A 3UM5A 4XT6A 1DHFA 1DR5A 3LG4A 4EIGA 3FQOA 3NXRA 5CC9A 4ELFA 6DFRA 1DREA 3SRWX 3SRUX 1LY3A 4Q6AA 3K45A 1DR7A 2FZHA 2W3AA 4QI9A 2OBCA 2W9TA 5HSRA 3K74A 4KM0A 3K2HA 2C2TA 3FS6A 4IXED 3SAIA 1ZDRA 4LAGX 5FDAA 2ANQA 3ROAA 2B3ZA 1DYIA 4XECX 1RF7A 3DAUA 4KBNA 3Q1HA 3EEKA 2G6VA 1M7AA 3F0QX 4KD7A 2INQA 3QGTA 3EX8A 1YHOA 3FRDX 2O7PA 1IA4A 3K47A 3JW3A 4GH8A 4HA7A 4PDJA 3FYWX 1DR1A 1RA1A 4DPDA 4QJZD 3NXXA 3NZDA 2CD2A 1DF7A 3CL9A 3F0VX 3S3VA 3EIGA 4M2XA 3FRFX 4X5GA 4P3RA 3NTZA 4XT5A 1AO8A 1RX1A 4PSTA 1DG8A 3NZ6X 3SRQX 3DATA 3INVA 1RH3A 4FGHA 3FY9X 4Q67A 4I1NA 3NRRA 3HBBA 4QLFA 1DG5A 2W3VA 3IRNA 3QLSA 3DFRA 4EIZA 1RX2A 3M09A 5HVBA 4KM2A 4P66A 3IX9A 1DAJA 1PD9A 3TQAA 1VJ3A 4FGGA 4XRBA 4KAKA 2H2QA 1RX6A 5U26A 4DPHA 1RB2A 4QHVA 2C2SA 2CIGA 4QLGA 3TD8A 1RX7A 3M08A 4OR7A 4ELHA 1RC4A 4X5JA 3F0XX 1J3KA 4KYAA 4G8ZX 1PD8A 2FZJA 4CD2A 1MVSA 2FZIA 4P3QA 4X5FA 4LEKX 3ZPGA 4I13A 3CD2A 3NZ9X 1RA8A 4KJKA 1IA1A 4TU5X 1HFRA 3EEJA 1RX5A 4H96A 1PDBA
chains in the Genus database with same CATH superfamily
3HJ3A 3NXVA 1KMSA 1RX3A 4H97A 3I8AX 3JTWA 3QYOA 1RD7A 3KFYA 3QLWA 4EJ1A 3F0BX 3JSUA 4ECKA 3JWMA 3UM8A 4KY4A 4IXGX 4M6JA 3SA1A 3QG2A 2HM9A 1OHKA 3KGYA 5HUIA 4HOFA 5U27A 1RX8A 4XT4A 1DR2A 3IA5A 1DDSA 2BLAA 3FRAX 3L3RA 3NZCX 1RE7A 2HXVA 3JWFA 3SRRX 2BLBA 3OAFA 5EAJA 3KJSA 3QLYA 4QLEA 4X5IA 1DDRA 1RX9A 3EELA 3QL3A 3R33A 3F8YA 1U72A 4M6KA 3KY8A 3IRMA 1DRHA 4KFJA 1RB3A 1J3IA 1DLRA 4KLXA 5HF2X 3CSEA 4PSYA 4XT8A 4QJCA 4G3MA 3QL0A 1QZFA 5HPBA 5HI6A 1RA9A 4ELBA 4M7VA 1JOMA 3DGAA 3GI2A 8DFRA 2L28A 3FYVX 2OIPA 4KNEA 3UM6A 3D80A 2D5NA 3JVXA 5ECXA 1DHJA 3E0BA 2ZZAA 3KJRA 5HT4A 3F8ZA 4NX7A 3I3RA 1RA2A 3TQ8A 4RGCA 3SA2A 5CCCA 4PTJA 2AZNA 3N0HA 1DR6A 3IA4A 3NZAX 4HOGA 3SQYX 3FQZA 5DFRA 3GHWA 1KLKA 1DISA 4P68A 4OSGA 1RX4A 4HA9A 2W3MA 1J3JA 3QFXA 5HF0X 3QLRA 2XW7A 3NU0A 1D1GA 5JA3A 3EEMA 4KJLA 1HFQA 4ELEA 2W9GA 4XE6X 3DRCA 1RA3A 3FL9A 3S7AA 1BOZA 1JOLA 1DRBA 1DLSA 1U70A 1DYJA 3DL5A 5HVEA 1DR4A 3FQVA 3IROA 4KY8A 3DL6A 4H95A 3NZBX 1DHIA 2P4GA 3JWKA 3JW5A 3ZPCA 1IA3A 4NX6A 1IA2A 2DHFA 2W3BA 1S3VA 1DYHA 5JG0X 3FY8X 4XT7A 4DDRA 3TQ9A 2QK8A 1HFPA 3F0UX 4DP3A 2W9SA 3SGYA 1AI9A 4EILA 4DFRA 5ECCA 5HT5A 3SH2A 3JWCA 5HQYA 1DRAA 1DR3A 1LUDA 3NXOA 3FQ0A 3NXYA 1M78A 1RG7A 1JUVA 4Q0EA 4ELGA 3GHVA 4KEBA 2ITHA 1VDRA 1TDRA 3FL8A 3FREX 4G95A 3F0SX 1DG7A 4X5HA 2W9HA 3S9UA 3FQFA 2DRCA 3NXTA 2D0KA 1CZ3A 3QLZA 3DG8A 1DYRA 4M7UA 1AOEA 5E8QA 1SEJA 3TQBA 4IXFX 2HQPA 1M79A 3GYFA 3VCOA 3OCHA 1MVTA 2ANOA 2GD9A 3QYLA 3FQCA 1LY4A 4FHBA 4KL9A 3RO9A 1U71A 1S3YA 1DIUA 4M6LA 3F91A 4PSSA 4LAHX 2JYBA 5DXVA 7DFRA 4HOEA 1DRFA 1S3WA 5HQZA 3RG9A 4LAEX 3SRSX 2KGKA 1E26A 3GHCA 4PTHA 3D84X 1S3UA 2LF1A 1KMVA 1OHJA 3FRBX 2BL9A 3QLXA 3CLBA 5HSUA 2BLCA 4Q0DA 4H98A 3SR5X 1BZFA 2W3WA 4KJJA 1CD2A 3UM5A 4XT6A 1DHFA 1DR5A 3LG4A 4EIGA 3FQOA 3NXRA 5CC9A 4ELFA 6DFRA 1DREA 3SRWX 3SRUX 1LY3A 4Q6AA 3K45A 1DR7A 2FZHA 2W3AA 4QI9A 2OBCA 2W9TA 5HSRA 3K74A 4KM0A 3K2HA 2C2TA 3FS6A 4IXED 3SAIA 1ZDRA 4LAGX 5FDAA 2ANQA 3ROAA 2B3ZA 1DYIA 4XECX 1RF7A 3DAUA 4KBNA 3Q1HA 3EEKA 2G6VA 1M7AA 3F0QX 4KD7A 2INQA 3QGTA 3EX8A 1YHOA 3FRDX 2O7PA 1IA4A 3K47A 3JW3A 4GH8A 4HA7A 4PDJA 3FYWX 1DR1A 1RA1A 4DPDA 4QJZD 3NXXA 3NZDA 2CD2A 1DF7A 3CL9A 3F0VX 3S3VA 3EIGA 4M2XA 3FRFX 4X5GA 4P3RA 3NTZA 4XT5A 1AO8A 1RX1A 4PSTA 1DG8A 3NZ6X 3SRQX 3DATA 3INVA 1RH3A 4FGHA 3FY9X 4Q67A 4I1NA 3NRRA 3HBBA 4QLFA 1DG5A 2W3VA 3IRNA 3QLSA 3DFRA 4EIZA 1RX2A 3M09A 5HVBA 4KM2A 4P66A 3IX9A 1DAJA 1PD9A 3TQAA 1VJ3A 4FGGA 4XRBA 4KAKA 2H2QA 1RX6A 5U26A 4DPHA 1RB2A 4QHVA 2C2SA 2CIGA 4QLGA 3TD8A 1RX7A 3M08A 4OR7A 4ELHA 1RC4A 4X5JA 3F0XX 1J3KA 4KYAA 4G8ZX 1PD8A 2FZJA 4CD2A 1MVSA 2FZIA 4P3QA 4X5FA 4LEKX 3ZPGA 4I13A 3CD2A 3NZ9X 1RA8A 4KJKA 1IA1A 4TU5X 1HFRA 3EEJA 1RX5A 4H96A 1PDBA
chains in the Genus database with same CATH topology
3HJ3A 3NXVA 1KMSA 1RX3A 4H97A 3I8AX 3JTWA 3QYOA 1RD7A 3KFYA 3QLWA 4EJ1A 3F0BX 3JSUA 4ECKA 3JWMA 3UM8A 4KY4A 4IXGX 4M6JA 3SA1A 3QG2A 2HM9A 1OHKA 3KGYA 5HUIA 4HOFA 5U27A 1RX8A 4XT4A 1DR2A 3IA5A 1DDSA 2BLAA 3FRAX 3L3RA 3NZCX 1RE7A 2HXVA 3JWFA 3SRRX 2BLBA 3OAFA 5EAJA 3KJSA 3QLYA 4QLEA 4X5IA 1DDRA 1RX9A 3EELA 3QL3A 3R33A 3F8YA 1U72A 4M6KA 3KY8A 3IRMA 1DRHA 4KFJA 1RB3A 1J3IA 1DLRA 4KLXA 5HF2X 3CSEA 4PSYA 4XT8A 4QJCA 4G3MA 3QL0A 1QZFA 5HPBA 5HI6A 1RA9A 4ELBA 4M7VA 1JOMA 3DGAA 3GI2A 8DFRA 2L28A 3FYVX 2OIPA 4KNEA 3UM6A 3D80A 2D5NA 3JVXA 5ECXA 1DHJA 3E0BA 2ZZAA 3KJRA 5HT4A 3F8ZA 4NX7A 3I3RA 1RA2A 3TQ8A 4RGCA 3SA2A 5CCCA 4PTJA 2AZNA 3N0HA 1DR6A 3IA4A 3NZAX 4HOGA 3SQYX 3FQZA 5DFRA 3GHWA 1KLKA 1DISA 4P68A 4OSGA 1RX4A 4HA9A 2W3MA 1J3JA 3QFXA 5HF0X 3QLRA 2XW7A 3NU0A 1D1GA 5JA3A 3EEMA 4KJLA 1HFQA 4ELEA 2W9GA 4XE6X 3DRCA 1RA3A 3FL9A 3S7AA 1BOZA 1JOLA 1DRBA 1DLSA 1U70A 1DYJA 3DL5A 5HVEA 1DR4A 3FQVA 3IROA 4KY8A 3DL6A 4H95A 3NZBX 1DHIA 2P4GA 3JWKA 3JW5A 3ZPCA 1IA3A 4NX6A 1IA2A 2DHFA 2W3BA 1S3VA 1DYHA 5JG0X 3FY8X 4XT7A 4DDRA 3TQ9A 2QK8A 1HFPA 3F0UX 4DP3A 2W9SA 3SGYA 1AI9A 4EILA 4DFRA 5ECCA 5HT5A 3SH2A 3JWCA 5HQYA 1DRAA 1DR3A 1LUDA 3NXOA 3FQ0A 3NXYA 1M78A 1RG7A 1JUVA 4Q0EA 4ELGA 3GHVA 4KEBA 2ITHA 1VDRA 1TDRA 3FL8A 3FREX 4G95A 3F0SX 1DG7A 4X5HA 2W9HA 3S9UA 3FQFA 2DRCA 3NXTA 2D0KA 1CZ3A 3QLZA 3DG8A 1DYRA 4M7UA 1AOEA 5E8QA 1SEJA 3TQBA 4IXFX 2HQPA 1M79A 3GYFA 3VCOA 3OCHA 1MVTA 2ANOA 2GD9A 3QYLA 3FQCA 1LY4A 4FHBA 4KL9A 3RO9A 1U71A 1S3YA 1DIUA 4M6LA 3F91A 4PSSA 4LAHX 2JYBA 5DXVA 7DFRA 4HOEA 1DRFA 1S3WA 5HQZA 3RG9A 4LAEX 3SRSX 2KGKA 1E26A 3GHCA 4PTHA 3D84X 1S3UA 2LF1A 1KMVA 1OHJA 3FRBX 2BL9A 3QLXA 3CLBA 5HSUA 2BLCA 4Q0DA 4H98A 3SR5X 1BZFA 2W3WA 4KJJA 1CD2A 3UM5A 4XT6A 1DHFA 1DR5A 3LG4A 4EIGA 3FQOA 3NXRA 5CC9A 4ELFA 6DFRA 1DREA 3SRWX 3SRUX 1LY3A 4Q6AA 3K45A 1DR7A 2FZHA 2W3AA 4QI9A 2OBCA 2W9TA 5HSRA 3K74A 4KM0A 3K2HA 2C2TA 3FS6A 4IXED 3SAIA 1ZDRA 4LAGX 5FDAA 2ANQA 3ROAA 2B3ZA 1DYIA 4XECX 1RF7A 3DAUA 4KBNA 3Q1HA 3EEKA 2G6VA 1M7AA 3F0QX 4KD7A 2INQA 3QGTA 3EX8A 1YHOA 3FRDX 2O7PA 1IA4A 3K47A 3JW3A 4GH8A 4HA7A 4PDJA 3FYWX 1DR1A 1RA1A 4DPDA 4QJZD 3NXXA 3NZDA 2CD2A 1DF7A 3CL9A 3F0VX 3S3VA 3EIGA 4M2XA 3FRFX 4X5GA 4P3RA 3NTZA 4XT5A 1AO8A 1RX1A 4PSTA 1DG8A 3NZ6X 3SRQX 3DATA 3INVA 1RH3A 4FGHA 3FY9X 4Q67A 4I1NA 3NRRA 3HBBA 4QLFA 1DG5A 2W3VA 3IRNA 3QLSA 3DFRA 4EIZA 1RX2A 3M09A 5HVBA 4KM2A 4P66A 3IX9A 1DAJA 1PD9A 3TQAA 1VJ3A 4FGGA 4XRBA 4KAKA 2H2QA 1RX6A 5U26A 4DPHA 1RB2A 4QHVA 2C2SA 2CIGA 4QLGA 3TD8A 1RX7A 3M08A 4OR7A 4ELHA 1RC4A 4X5JA 3F0XX 1J3KA 4KYAA 4G8ZX 1PD8A 2FZJA 4CD2A 1MVSA 2FZIA 4P3QA 4X5FA 4LEKX 3ZPGA 4I13A 3CD2A 3NZ9X 1RA8A 4KJKA 1IA1A 4TU5X 1HFRA 3EEJA 1RX5A 4H96A 1PDBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3HJ3 A;  3NXV A;  1KMS A;  1RX3 A;  4H97 A;  3I8A X;  3JTW A;  3QYO A;  1RD7 A;  3KFY A;  3QLW A;  4EJ1 A;  3F0B X;  3JSU A;  4ECK A;  3JWM A;  3UM8 A;  4KY4 A;  4IXG X;  4M6J A;  3SA1 A;  3QG2 A;  2HM9 A;  1OHK A;  3KGY A;  5HUI A;  4HOF A;  5U27 A;  1RX8 A;  4XT4 A;  1DR2 A;  3IA5 A;  1DDS A;  2BLA A;  3FRA X;  3L3R A;  3NZC X;  1RE7 A;  2HXV A;  3JWF A;  3SRR X;  2BLB A;  3OAF A;  5EAJ A;  3KJS A;  3QLY A;  4QLE A;  4X5I A;  1DDR A;  1RX9 A;  3EEL A;  3QL3 A;  3R33 A;  3F8Y A;  1U72 A;  4M6K A;  3KY8 A;  3IRM A;  1DRH A;  4KFJ A;  1RB3 A;  1J3I A;  1DLR A;  4KLX A;  5HF2 X;  3CSE A;  4PSY A;  4XT8 A;  4QJC A;  4G3M A;  3QL0 A;  1QZF A;  5HPB A;  5HI6 A;  1RA9 A;  4ELB A;  4M7V A;  1JOM A;  3DGA A;  3GI2 A;  8DFR A;  2L28 A;  3FYV X;  2OIP A;  4KNE A;  3UM6 A;  3D80 A;  2D5N A;  3JVX A;  5ECX A;  1DHJ A;  3E0B A;  2ZZA A;  3KJR A;  5HT4 A;  3F8Z A;  4NX7 A;  3I3R A;  1RA2 A;  3TQ8 A;  4RGC A;  3SA2 A;  5CCC A;  4PTJ A;  2AZN A;  3N0H A;  1DR6 A;  3IA4 A;  3NZA X;  4HOG A;  3SQY X;  3FQZ A;  5DFR A;  3GHW A;  1KLK A;  1DIS A;  4P68 A;  4OSG A;  1RX4 A;  4HA9 A;  2W3M A;  1J3J A;  3QFX A;  5HF0 X;  3QLR A;  2XW7 A;  3NU0 A;  1D1G A;  5JA3 A;  3EEM A;  4KJL A;  1HFQ A;  4ELE A;  2W9G A;  4XE6 X;  3DRC A;  1RA3 A;  3FL9 A;  3S7A A;  1BOZ A;  1JOL A;  1DRB A;  1DLS A;  1U70 A;  1DYJ A;  3DL5 A;  5HVE A;  1DR4 A;  3FQV A;  3IRO A;  4KY8 A;  3DL6 A;  4H95 A;  3NZB X;  1DHI A;  2P4G A;  3JWK A;  3JW5 A;  3ZPC A;  1IA3 A;  4NX6 A;  1IA2 A;  2DHF A;  2W3B A;  1S3V A;  1DYH A;  5JG0 X;  3FY8 X;  4XT7 A;  4DDR A;  3TQ9 A;  2QK8 A;  1HFP A;  3F0U X;  4DP3 A;  2W9S A;  3SGY A;  1AI9 A;  4EIL A;  4DFR A;  5ECC A;  5HT5 A;  3SH2 A;  3JWC A;  5HQY A;  1DRA A;  1DR3 A;  1LUD A;  3NXO A;  3FQ0 A;  3NXY A;  1M78 A;  1RG7 A;  1JUV A;  4Q0E A;  4ELG A;  3GHV A;  4KEB A;  2ITH A;  1VDR A;  1TDR A;  3FL8 A;  3FRE X;  4G95 A;  3F0S X;  1DG7 A;  4X5H A;  2W9H A;  3S9U A;  3FQF A;  2DRC A;  3NXT A;  2D0K A;  1CZ3 A;  3QLZ A;  3DG8 A;  1DYR A;  4M7U A;  1AOE A;  5E8Q A;  1SEJ A;  3TQB A;  4IXF X;  2HQP A;  1M79 A;  3GYF A;  3VCO A;  3OCH A;  1MVT A;  2ANO A;  2GD9 A;  3QYL A;  3FQC A;  1LY4 A;  4FHB A;  4KL9 A;  3RO9 A;  1U71 A;  1S3Y A;  1DIU A;  4M6L A;  3F91 A;  4PSS A;  4LAH X;  2JYB A;  5DXV A;  7DFR A;  4HOE A;  1DRF A;  1S3W A;  5HQZ A;  3RG9 A;  4LAE X;  3SRS X;  2KGK A;  1E26 A;  3GHC A;  4PTH A;  3D84 X;  1S3U A;  2LF1 A;  1KMV A;  1OHJ A;  3FRB X;  2BL9 A;  3QLX A;  3CLB A;  5HSU A;  2BLC A;  4Q0D A;  4H98 A;  3SR5 X;  1BZF A;  2W3W A;  4KJJ A;  1CD2 A;  3UM5 A;  4XT6 A;  1DHF A;  1DR5 A;  3LG4 A;  4EIG A;  3FQO A;  3NXR A;  5CC9 A;  4ELF A;  6DFR A;  1DRE A;  3SRW X;  3SRU X;  1LY3 A;  4Q6A A;  3K45 A;  1DR7 A;  2FZH A;  2W3A A;  4QI9 A;  2OBC A;  2W9T A;  5HSR A;  3K74 A;  4KM0 A;  3K2H A;  2C2T A;  3FS6 A;  4IXE D;  3SAI A;  1ZDR A;  4LAG X;  5FDA A;  2ANQ A;  3ROA A;  2B3Z A;  1DYI A;  4XEC X;  1RF7 A;  3DAU A;  4KBN A;  3Q1H A;  3EEK A;  2G6V A;  1M7A A;  3F0Q X;  4KD7 A;  2INQ A;  3QGT A;  3EX8 A;  1YHO A;  3FRD X;  2O7P A;  1IA4 A;  3K47 A;  3JW3 A;  4GH8 A;  4HA7 A;  4PDJ A;  3FYW X;  1DR1 A;  1RA1 A;  4DPD A;  4QJZ D;  3NXX A;  3NZD A;  2CD2 A;  1DF7 A;  3CL9 A;  3F0V X;  3S3V A;  3EIG A;  4M2X A;  3FRF X;  4X5G A;  4P3R A;  3NTZ A;  4XT5 A;  1AO8 A;  1RX1 A;  4PST A;  1DG8 A;  3NZ6 X;  3SRQ X;  3DAT A;  3INV A;  1RH3 A;  4FGH A;  3FY9 X;  4Q67 A;  4I1N A;  3NRR A;  3HBB A;  4QLF A;  1DG5 A;  2W3V A;  3IRN A;  3QLS A;  3DFR A;  4EIZ A;  1RX2 A;  3M09 A;  5HVB A;  4KM2 A;  4P66 A;  3IX9 A;  1DAJ A;  1PD9 A;  3TQA A;  1VJ3 A;  4FGG A;  4XRB A;  4KAK A;  2H2Q A;  1RX6 A;  5U26 A;  4DPH A;  1RB2 A;  4QHV A;  2C2S A;  2CIG A;  4QLG A;  3TD8 A;  1RX7 A;  3M08 A;  4OR7 A;  4ELH A;  1RC4 A;  4X5J A;  3F0X X;  1J3K A;  4KYA A;  4G8Z X;  1PD8 A;  2FZJ A;  4CD2 A;  1MVS A;  2FZI A;  4P3Q A;  4X5F A;  4LEK X;  3ZPG A;  4I13 A;  3CD2 A;  3NZ9 X;  1RA8 A;  4KJK A;  1IA1 A;  4TU5 X;  1HFR A;  3EEJ A;  1RX5 A;  4H96 A;  1PDB A; 
#chains in the Genus database with same CATH topology
 3HJ3 A;  3NXV A;  1KMS A;  1RX3 A;  4H97 A;  3I8A X;  3JTW A;  3QYO A;  1RD7 A;  3KFY A;  3QLW A;  4EJ1 A;  3F0B X;  3JSU A;  4ECK A;  3JWM A;  3UM8 A;  4KY4 A;  4IXG X;  4M6J A;  3SA1 A;  3QG2 A;  2HM9 A;  1OHK A;  3KGY A;  5HUI A;  4HOF A;  5U27 A;  1RX8 A;  4XT4 A;  1DR2 A;  3IA5 A;  1DDS A;  2BLA A;  3FRA X;  3L3R A;  3NZC X;  1RE7 A;  2HXV A;  3JWF A;  3SRR X;  2BLB A;  3OAF A;  5EAJ A;  3KJS A;  3QLY A;  4QLE A;  4X5I A;  1DDR A;  1RX9 A;  3EEL A;  3QL3 A;  3R33 A;  3F8Y A;  1U72 A;  4M6K A;  3KY8 A;  3IRM A;  1DRH A;  4KFJ A;  1RB3 A;  1J3I A;  1DLR A;  4KLX A;  5HF2 X;  3CSE A;  4PSY A;  4XT8 A;  4QJC A;  4G3M A;  3QL0 A;  1QZF A;  5HPB A;  5HI6 A;  1RA9 A;  4ELB A;  4M7V A;  1JOM A;  3DGA A;  3GI2 A;  8DFR A;  2L28 A;  3FYV X;  2OIP A;  4KNE A;  3UM6 A;  3D80 A;  2D5N A;  3JVX A;  5ECX A;  1DHJ A;  3E0B A;  2ZZA A;  3KJR A;  5HT4 A;  3F8Z A;  4NX7 A;  3I3R A;  1RA2 A;  3TQ8 A;  4RGC A;  3SA2 A;  5CCC A;  4PTJ A;  2AZN A;  3N0H A;  1DR6 A;  3IA4 A;  3NZA X;  4HOG A;  3SQY X;  3FQZ A;  5DFR A;  3GHW A;  1KLK A;  1DIS A;  4P68 A;  4OSG A;  1RX4 A;  4HA9 A;  2W3M A;  1J3J A;  3QFX A;  5HF0 X;  3QLR A;  2XW7 A;  3NU0 A;  1D1G A;  5JA3 A;  3EEM A;  4KJL A;  1HFQ A;  4ELE A;  2W9G A;  4XE6 X;  3DRC A;  1RA3 A;  3FL9 A;  3S7A A;  1BOZ A;  1JOL A;  1DRB A;  1DLS A;  1U70 A;  1DYJ A;  3DL5 A;  5HVE A;  1DR4 A;  3FQV A;  3IRO A;  4KY8 A;  3DL6 A;  4H95 A;  3NZB X;  1DHI A;  2P4G A;  3JWK A;  3JW5 A;  3ZPC A;  1IA3 A;  4NX6 A;  1IA2 A;  2DHF A;  2W3B A;  1S3V A;  1DYH A;  5JG0 X;  3FY8 X;  4XT7 A;  4DDR A;  3TQ9 A;  2QK8 A;  1HFP A;  3F0U X;  4DP3 A;  2W9S A;  3SGY A;  1AI9 A;  4EIL A;  4DFR A;  5ECC A;  5HT5 A;  3SH2 A;  3JWC A;  5HQY A;  1DRA A;  1DR3 A;  1LUD A;  3NXO A;  3FQ0 A;  3NXY A;  1M78 A;  1RG7 A;  1JUV A;  4Q0E A;  4ELG A;  3GHV A;  4KEB A;  2ITH A;  1VDR A;  1TDR A;  3FL8 A;  3FRE X;  4G95 A;  3F0S X;  1DG7 A;  4X5H A;  2W9H A;  3S9U A;  3FQF A;  2DRC A;  3NXT A;  2D0K A;  1CZ3 A;  3QLZ A;  3DG8 A;  1DYR A;  4M7U A;  1AOE A;  5E8Q A;  1SEJ A;  3TQB A;  4IXF X;  2HQP A;  1M79 A;  3GYF A;  3VCO A;  3OCH A;  1MVT A;  2ANO A;  2GD9 A;  3QYL A;  3FQC A;  1LY4 A;  4FHB A;  4KL9 A;  3RO9 A;  1U71 A;  1S3Y A;  1DIU A;  4M6L A;  3F91 A;  4PSS A;  4LAH X;  2JYB A;  5DXV A;  7DFR A;  4HOE A;  1DRF A;  1S3W A;  5HQZ A;  3RG9 A;  4LAE X;  3SRS X;  2KGK A;  1E26 A;  3GHC A;  4PTH A;  3D84 X;  1S3U A;  2LF1 A;  1KMV A;  1OHJ A;  3FRB X;  2BL9 A;  3QLX A;  3CLB A;  5HSU A;  2BLC A;  4Q0D A;  4H98 A;  3SR5 X;  1BZF A;  2W3W A;  4KJJ A;  1CD2 A;  3UM5 A;  4XT6 A;  1DHF A;  1DR5 A;  3LG4 A;  4EIG A;  3FQO A;  3NXR A;  5CC9 A;  4ELF A;  6DFR A;  1DRE A;  3SRW X;  3SRU X;  1LY3 A;  4Q6A A;  3K45 A;  1DR7 A;  2FZH A;  2W3A A;  4QI9 A;  2OBC A;  2W9T A;  5HSR A;  3K74 A;  4KM0 A;  3K2H A;  2C2T A;  3FS6 A;  4IXE D;  3SAI A;  1ZDR A;  4LAG X;  5FDA A;  2ANQ A;  3ROA A;  2B3Z A;  1DYI A;  4XEC X;  1RF7 A;  3DAU A;  4KBN A;  3Q1H A;  3EEK A;  2G6V A;  1M7A A;  3F0Q X;  4KD7 A;  2INQ A;  3QGT A;  3EX8 A;  1YHO A;  3FRD X;  2O7P A;  1IA4 A;  3K47 A;  3JW3 A;  4GH8 A;  4HA7 A;  4PDJ A;  3FYW X;  1DR1 A;  1RA1 A;  4DPD A;  4QJZ D;  3NXX A;  3NZD A;  2CD2 A;  1DF7 A;  3CL9 A;  3F0V X;  3S3V A;  3EIG A;  4M2X A;  3FRF X;  4X5G A;  4P3R A;  3NTZ A;  4XT5 A;  1AO8 A;  1RX1 A;  4PST A;  1DG8 A;  3NZ6 X;  3SRQ X;  3DAT A;  3INV A;  1RH3 A;  4FGH A;  3FY9 X;  4Q67 A;  4I1N A;  3NRR A;  3HBB A;  4QLF A;  1DG5 A;  2W3V A;  3IRN A;  3QLS A;  3DFR A;  4EIZ A;  1RX2 A;  3M09 A;  5HVB A;  4KM2 A;  4P66 A;  3IX9 A;  1DAJ A;  1PD9 A;  3TQA A;  1VJ3 A;  4FGG A;  4XRB A;  4KAK A;  2H2Q A;  1RX6 A;  5U26 A;  4DPH A;  1RB2 A;  4QHV A;  2C2S A;  2CIG A;  4QLG A;  3TD8 A;  1RX7 A;  3M08 A;  4OR7 A;  4ELH A;  1RC4 A;  4X5J A;  3F0X X;  1J3K A;  4KYA A;  4G8Z X;  1PD8 A;  2FZJ A;  4CD2 A;  1MVS A;  2FZI A;  4P3Q A;  4X5F A;  4LEK X;  3ZPG A;  4I13 A;  3CD2 A;  3NZ9 X;  1RA8 A;  4KJK A;  1IA1 A;  4TU5 X;  1HFR A;  3EEJ A;  1RX5 A;  4H96 A;  1PDB A; 
#chains in the Genus database with same CATH homology
 3HJ3 A;  3NXV A;  1KMS A;  1RX3 A;  4H97 A;  3I8A X;  3JTW A;  3QYO A;  1RD7 A;  3KFY A;  3QLW A;  4EJ1 A;  3F0B X;  3JSU A;  4ECK A;  3JWM A;  3UM8 A;  4KY4 A;  4IXG X;  4M6J A;  3SA1 A;  3QG2 A;  2HM9 A;  1OHK A;  3KGY A;  5HUI A;  4HOF A;  5U27 A;  1RX8 A;  4XT4 A;  1DR2 A;  3IA5 A;  1DDS A;  2BLA A;  3FRA X;  3L3R A;  3NZC X;  1RE7 A;  2HXV A;  3JWF A;  3SRR X;  2BLB A;  3OAF A;  5EAJ A;  3KJS A;  3QLY A;  4QLE A;  4X5I A;  1DDR A;  1RX9 A;  3EEL A;  3QL3 A;  3R33 A;  3F8Y A;  1U72 A;  4M6K A;  3KY8 A;  3IRM A;  1DRH A;  4KFJ A;  1RB3 A;  1J3I A;  1DLR A;  4KLX A;  5HF2 X;  3CSE A;  4PSY A;  4XT8 A;  4QJC A;  4G3M A;  3QL0 A;  1QZF A;  5HPB A;  5HI6 A;  1RA9 A;  4ELB A;  4M7V A;  1JOM A;  3DGA A;  3GI2 A;  8DFR A;  2L28 A;  3FYV X;  2OIP A;  4KNE A;  3UM6 A;  3D80 A;  2D5N A;  3JVX A;  5ECX A;  1DHJ A;  3E0B A;  2ZZA A;  3KJR A;  5HT4 A;  3F8Z A;  4NX7 A;  3I3R A;  1RA2 A;  3TQ8 A;  4RGC A;  3SA2 A;  5CCC A;  4PTJ A;  2AZN A;  3N0H A;  1DR6 A;  3IA4 A;  3NZA X;  4HOG A;  3SQY X;  3FQZ A;  5DFR A;  3GHW A;  1KLK A;  1DIS A;  4P68 A;  4OSG A;  1RX4 A;  4HA9 A;  2W3M A;  1J3J A;  3QFX A;  5HF0 X;  3QLR A;  2XW7 A;  3NU0 A;  1D1G A;  5JA3 A;  3EEM A;  4KJL A;  1HFQ A;  4ELE A;  2W9G A;  4XE6 X;  3DRC A;  1RA3 A;  3FL9 A;  3S7A A;  1BOZ A;  1JOL A;  1DRB A;  1DLS A;  1U70 A;  1DYJ A;  3DL5 A;  5HVE A;  1DR4 A;  3FQV A;  3IRO A;  4KY8 A;  3DL6 A;  4H95 A;  3NZB X;  1DHI A;  2P4G A;  3JWK A;  3JW5 A;  3ZPC A;  1IA3 A;  4NX6 A;  1IA2 A;  2DHF A;  2W3B A;  1S3V A;  1DYH A;  5JG0 X;  3FY8 X;  4XT7 A;  4DDR A;  3TQ9 A;  2QK8 A;  1HFP A;  3F0U X;  4DP3 A;  2W9S A;  3SGY A;  1AI9 A;  4EIL A;  4DFR A;  5ECC A;  5HT5 A;  3SH2 A;  3JWC A;  5HQY A;  1DRA A;  1DR3 A;  1LUD A;  3NXO A;  3FQ0 A;  3NXY A;  1M78 A;  1RG7 A;  1JUV A;  4Q0E A;  4ELG A;  3GHV A;  4KEB A;  2ITH A;  1VDR A;  1TDR A;  3FL8 A;  3FRE X;  4G95 A;  3F0S X;  1DG7 A;  4X5H A;  2W9H A;  3S9U A;  3FQF A;  2DRC A;  3NXT A;  2D0K A;  1CZ3 A;  3QLZ A;  3DG8 A;  1DYR A;  4M7U A;  1AOE A;  5E8Q A;  1SEJ A;  3TQB A;  4IXF X;  2HQP A;  1M79 A;  3GYF A;  3VCO A;  3OCH A;  1MVT A;  2ANO A;  2GD9 A;  3QYL A;  3FQC A;  1LY4 A;  4FHB A;  4KL9 A;  3RO9 A;  1U71 A;  1S3Y A;  1DIU A;  4M6L A;  3F91 A;  4PSS A;  4LAH X;  2JYB A;  5DXV A;  7DFR A;  4HOE A;  1DRF A;  1S3W A;  5HQZ A;  3RG9 A;  4LAE X;  3SRS X;  2KGK A;  1E26 A;  3GHC A;  4PTH A;  3D84 X;  1S3U A;  2LF1 A;  1KMV A;  1OHJ A;  3FRB X;  2BL9 A;  3QLX A;  3CLB A;  5HSU A;  2BLC A;  4Q0D A;  4H98 A;  3SR5 X;  1BZF A;  2W3W A;  4KJJ A;  1CD2 A;  3UM5 A;  4XT6 A;  1DHF A;  1DR5 A;  3LG4 A;  4EIG A;  3FQO A;  3NXR A;  5CC9 A;  4ELF A;  6DFR A;  1DRE A;  3SRW X;  3SRU X;  1LY3 A;  4Q6A A;  3K45 A;  1DR7 A;  2FZH A;  2W3A A;  4QI9 A;  2OBC A;  2W9T A;  5HSR A;  3K74 A;  4KM0 A;  3K2H A;  2C2T A;  3FS6 A;  4IXE D;  3SAI A;  1ZDR A;  4LAG X;  5FDA A;  2ANQ A;  3ROA A;  2B3Z A;  1DYI A;  4XEC X;  1RF7 A;  3DAU A;  4KBN A;  3Q1H A;  3EEK A;  2G6V A;  1M7A A;  3F0Q X;  4KD7 A;  2INQ A;  3QGT A;  3EX8 A;  1YHO A;  3FRD X;  2O7P A;  1IA4 A;  3K47 A;  3JW3 A;  4GH8 A;  4HA7 A;  4PDJ A;  3FYW X;  1DR1 A;  1RA1 A;  4DPD A;  4QJZ D;  3NXX A;  3NZD A;  2CD2 A;  1DF7 A;  3CL9 A;  3F0V X;  3S3V A;  3EIG A;  4M2X A;  3FRF X;  4X5G A;  4P3R A;  3NTZ A;  4XT5 A;  1AO8 A;  1RX1 A;  4PST A;  1DG8 A;  3NZ6 X;  3SRQ X;  3DAT A;  3INV A;  1RH3 A;  4FGH A;  3FY9 X;  4Q67 A;  4I1N A;  3NRR A;  3HBB A;  4QLF A;  1DG5 A;  2W3V A;  3IRN A;  3QLS A;  3DFR A;  4EIZ A;  1RX2 A;  3M09 A;  5HVB A;  4KM2 A;  4P66 A;  3IX9 A;  1DAJ A;  1PD9 A;  3TQA A;  1VJ3 A;  4FGG A;  4XRB A;  4KAK A;  2H2Q A;  1RX6 A;  5U26 A;  4DPH A;  1RB2 A;  4QHV A;  2C2S A;  2CIG A;  4QLG A;  3TD8 A;  1RX7 A;  3M08 A;  4OR7 A;  4ELH A;  1RC4 A;  4X5J A;  3F0X X;  1J3K A;  4KYA A;  4G8Z X;  1PD8 A;  2FZJ A;  4CD2 A;  1MVS A;  2FZI A;  4P3Q A;  4X5F A;  4LEK X;  3ZPG A;  4I13 A;  3CD2 A;  3NZ9 X;  1RA8 A;  4KJK A;  1IA1 A;  4TU5 X;  1HFR A;  3EEJ A;  1RX5 A;  4H96 A;  1PDB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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