1RC4A

Dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and nicotinamide adenine dinucleotide phosphate (oxidized form)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 40
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rc4A00
4EIGA 1DG5A 2W9TA 3SRQX 4I13A 1J3JA 1BOZA 1SEJA 1DISA 4GH8A 3F0VX 4XT6A 3CL9A 3JWCA 4P66A 3F0QX 1IA4A 3NU0A 3Q1HA 3JWKA 3FS6A 1DLSA 2W9SA 3EEMA 1RX4A 1PD9A 3KY8A 1S3WA 3FYVX 3NXXA 2CIGA 1KMVA 4QJCA 2QK8A 1DG8A 1U70A 3IRMA 1RC4A 3NRRA 4ELFA 1DG7A 1VJ3A 4I1NA 3IX9A 4CD2A 3K47A 1DYJA 4KL9A 4RGCA 4LEKX 1RA9A 3QL3A 1RH3A 1BZFA 4HOEA 1HFRA 1DRAA 3D80A 1RA8A 3GHVA 3SRRX 2P4GA 4H97A 3RG9A 3DATA 3S3VA 5U26A 1RX6A 4ELGA 3QFXA 4ELBA 3FL9A 4EILA 2C2SA 4H96A 3DRCA 3FQVA 2BLBA 1U71A 2W3WA 4X5IA 3GHCA 3NZ9X 4P68A 4H95A 1RX1A 3NZBX 3NXTA 3JSUA 2W9GA 4FGHA 1DLRA 4ELEA 4KYAA 3FREX 3KJRA 4M2XA 4M6JA 1DYRA 2C2TA 4IXFX 3NZ6X 3HJ3A 4X5GA 5HF2X 5HQYA 3JW3A 4LAHX 4QLGA 3R33A 2DRCA 2FZIA 1PD8A 4QHVA 3CLBA 1AI9A 1M78A 3TQBA 1DRBA 5HI6A 3SA2A 3JWFA 3QLZA 3TD8A 4EJ1A 4M6LA 1DR5A 1DHFA 1E26A 3SR5X 3TQ8A 1DR3A 1KMSA 4M7UA 2W9HA 3OAFA 4M6KA 3JW5A 5HSUA 4XT5A 2W3AA 3IRNA 1RX7A 5HPBA 4HA7A 4XT7A 1KLKA 1CD2A 4PSYA 3UM6A 3QGTA 1RB2A 3SQYX 5JG0X 4H98A 1S3YA 1DHJA 5FDAA 3I8AX 3IROA 3JTWA 1YHOA 3SGYA 5DXVA 4PDJA 1U72A 4KJLA 1M79A 4Q0EA 2XW7A 1JOMA 3IA5A 4HOFA 2B3ZA 4IXGX 2ITHA 5HVEA 3NXYA 1RA1A 1M7AA 3EEKA 5HT4A 1IA3A 4KY4A 1RX9A 1DRHA 3DL6A 3SAIA 4FHBA 3FY8X 3ZPGA 3SA1A 3ZPCA 3D84X 3NXVA 2ANQA 1ZDRA 3DFRA 4PSTA 1JUVA 2HM9A 1TDRA 4X5JA 3FL8A 3FY9X 4M7VA 5HQZA 5DFRA 4KM0A 3F91A 4KBNA 1PDBA 4XT4A 2D5NA 3QYOA 1RX8A 3INVA 4DP3A 1S3UA 1RG7A 2H2QA 3QYLA 1OHKA 4QLFA 3N0HA 3TQAA 3ROAA 5ECXA 5E8QA 2BL9A 4Q67A 3FQ0A 4KFJA 3K74A 4P3RA 3SRWX 1LY4A 4KAKA 3NZCX 6DFRA 5HT5A 2HQPA 1LUDA 1JOLA 3SH2A 4XT8A 1DDSA 1RE7A 5CCCA 3GYFA 1RA3A 3FRFX 1DR4A 4OSGA 3DL5A 4XE6X 1D1GA 3FRDX 1RD7A 4DDRA 1S3VA 2BLCA 2L28A 4QJZD 3F0UX 1HFPA 3FQZA 3DGAA 3VCOA 2FZHA 4Q6AA 1AOEA 3JWMA 4PTJA 2DHFA 4DFRA 2FZJA 3QLXA 2KGKA 1DHIA 3FQCA 3M09A 5HUIA 4KLXA 3QL0A 2JYBA 3GI2A 4ELHA 1RX5A 3K2HA 3NXOA 3QG2A 4PSSA 2W3BA 4Q0DA 4G3MA 3CSEA 3NTZA 2D0KA 5EAJA 2INQA 5U27A 3KFYA 3EELA 4KJKA 1DREA 1IA2A 1RX3A 1J3IA 3RO9A 3UM8A 4NX6A 7DFRA 3I3RA 4KNEA 3L3RA 3QLRA 2AZNA 3DG8A 3LG4A 1J3KA 3M08A 3S7AA 4HOGA 3TQ9A 1DR1A 5ECCA 3QLYA 4LAGX 4DPHA 4QI9A 4KEBA 4TU5X 3IA4A 2O7PA 4OR7A 2BLAA 2OIPA 4X5HA 1LY3A 1RB3A 4ECKA 4XECX 3QLSA 3F8YA 2G6VA 1IA1A 1HFQA 4IXED 1RA2A 3F0BX 5HF0X 1MVSA 4XRBA 3KJSA 3SRSX 1DR7A 3JVXA 2OBCA 3E0BA 5JA3A 1DF7A 4HA9A 1QZFA 1RX2A 1DYIA 3K45A 4G8ZX 1DYHA 2ANOA 2CD2A 1MVTA 2LF1A 4PTHA 4FGGA 3F0XX 4P3QA 3NXRA 3QLWA 2ZZAA 4KJJA 1OHJA 4LAEX 4DPDA 3FRAX 3UM5A 4NX7A 3FQFA 3GHWA 3DAUA 1VDRA 1AO8A 2W3VA 3KGYA 4EIZA 2W3MA 1DR2A 8DFRA 3FYWX 2HXVA 3NZAX 5HSRA 1CZ3A 3EIGA 3HBBA 3S9UA 1DAJA 3CD2A 3FQOA 3NZDA 1DRFA 1RF7A 2GD9A 4G95A 4X5FA 3EEJA 4QLEA 3F0SX 1DDRA 4KD7A 4KM2A 3FRBX 3EX8A 1DIUA 4KY8A 5CC9A 5HVBA 3OCHA 3SRUX 1DR6A 3F8ZA
chains in the Genus database with same CATH superfamily
4EIGA 1DG5A 2W9TA 3SRQX 4I13A 1J3JA 1BOZA 1SEJA 1DISA 4GH8A 3F0VX 4XT6A 3CL9A 3JWCA 4P66A 3F0QX 1IA4A 3NU0A 3Q1HA 3JWKA 3FS6A 1DLSA 2W9SA 3EEMA 1RX4A 1PD9A 3KY8A 1S3WA 3FYVX 3NXXA 2CIGA 1KMVA 4QJCA 2QK8A 1DG8A 1U70A 3IRMA 1RC4A 3NRRA 4ELFA 1DG7A 1VJ3A 4I1NA 3IX9A 4CD2A 3K47A 1DYJA 4KL9A 4RGCA 4LEKX 1RA9A 3QL3A 1RH3A 1BZFA 4HOEA 1HFRA 1DRAA 3D80A 1RA8A 3GHVA 3SRRX 2P4GA 4H97A 3RG9A 3DATA 3S3VA 5U26A 1RX6A 4ELGA 3QFXA 4ELBA 3FL9A 4EILA 2C2SA 4H96A 3DRCA 3FQVA 2BLBA 1U71A 2W3WA 4X5IA 3GHCA 3NZ9X 4P68A 4H95A 1RX1A 3NZBX 3NXTA 3JSUA 2W9GA 4FGHA 1DLRA 4ELEA 4KYAA 3FREX 3KJRA 4M2XA 4M6JA 1DYRA 2C2TA 4IXFX 3NZ6X 3HJ3A 4X5GA 5HF2X 5HQYA 3JW3A 4LAHX 4QLGA 3R33A 2DRCA 2FZIA 1PD8A 4QHVA 3CLBA 1AI9A 1M78A 3TQBA 1DRBA 5HI6A 3SA2A 3JWFA 3QLZA 3TD8A 4EJ1A 4M6LA 1DR5A 1DHFA 1E26A 3SR5X 3TQ8A 1DR3A 1KMSA 4M7UA 2W9HA 3OAFA 4M6KA 3JW5A 5HSUA 4XT5A 2W3AA 3IRNA 1RX7A 5HPBA 4HA7A 4XT7A 1KLKA 1CD2A 4PSYA 3UM6A 3QGTA 1RB2A 3SQYX 5JG0X 4H98A 1S3YA 1DHJA 5FDAA 3I8AX 3IROA 3JTWA 1YHOA 3SGYA 5DXVA 4PDJA 1U72A 4KJLA 1M79A 4Q0EA 2XW7A 1JOMA 3IA5A 4HOFA 2B3ZA 4IXGX 2ITHA 5HVEA 3NXYA 1RA1A 1M7AA 3EEKA 5HT4A 1IA3A 4KY4A 1RX9A 1DRHA 3DL6A 3SAIA 4FHBA 3FY8X 3ZPGA 3SA1A 3ZPCA 3D84X 3NXVA 2ANQA 1ZDRA 3DFRA 4PSTA 1JUVA 2HM9A 1TDRA 4X5JA 3FL8A 3FY9X 4M7VA 5HQZA 5DFRA 4KM0A 3F91A 4KBNA 1PDBA 4XT4A 2D5NA 3QYOA 1RX8A 3INVA 4DP3A 1S3UA 1RG7A 2H2QA 3QYLA 1OHKA 4QLFA 3N0HA 3TQAA 3ROAA 5ECXA 5E8QA 2BL9A 4Q67A 3FQ0A 4KFJA 3K74A 4P3RA 3SRWX 1LY4A 4KAKA 3NZCX 6DFRA 5HT5A 2HQPA 1LUDA 1JOLA 3SH2A 4XT8A 1DDSA 1RE7A 5CCCA 3GYFA 1RA3A 3FRFX 1DR4A 4OSGA 3DL5A 4XE6X 1D1GA 3FRDX 1RD7A 4DDRA 1S3VA 2BLCA 2L28A 4QJZD 3F0UX 1HFPA 3FQZA 3DGAA 3VCOA 2FZHA 4Q6AA 1AOEA 3JWMA 4PTJA 2DHFA 4DFRA 2FZJA 3QLXA 2KGKA 1DHIA 3FQCA 3M09A 5HUIA 4KLXA 3QL0A 2JYBA 3GI2A 4ELHA 1RX5A 3K2HA 3NXOA 3QG2A 4PSSA 2W3BA 4Q0DA 4G3MA 3CSEA 3NTZA 2D0KA 5EAJA 2INQA 5U27A 3KFYA 3EELA 4KJKA 1DREA 1IA2A 1RX3A 1J3IA 3RO9A 3UM8A 4NX6A 7DFRA 3I3RA 4KNEA 3L3RA 3QLRA 2AZNA 3DG8A 3LG4A 1J3KA 3M08A 3S7AA 4HOGA 3TQ9A 1DR1A 5ECCA 3QLYA 4LAGX 4DPHA 4QI9A 4KEBA 4TU5X 3IA4A 2O7PA 4OR7A 2BLAA 2OIPA 4X5HA 1LY3A 1RB3A 4ECKA 4XECX 3QLSA 3F8YA 2G6VA 1IA1A 1HFQA 4IXED 1RA2A 3F0BX 5HF0X 1MVSA 4XRBA 3KJSA 3SRSX 1DR7A 3JVXA 2OBCA 3E0BA 5JA3A 1DF7A 4HA9A 1QZFA 1RX2A 1DYIA 3K45A 4G8ZX 1DYHA 2ANOA 2CD2A 1MVTA 2LF1A 4PTHA 4FGGA 3F0XX 4P3QA 3NXRA 3QLWA 2ZZAA 4KJJA 1OHJA 4LAEX 4DPDA 3FRAX 3UM5A 4NX7A 3FQFA 3GHWA 3DAUA 1VDRA 1AO8A 2W3VA 3KGYA 4EIZA 2W3MA 1DR2A 8DFRA 3FYWX 2HXVA 3NZAX 5HSRA 1CZ3A 3EIGA 3HBBA 3S9UA 1DAJA 3CD2A 3FQOA 3NZDA 1DRFA 1RF7A 2GD9A 4G95A 4X5FA 3EEJA 4QLEA 3F0SX 1DDRA 4KD7A 4KM2A 3FRBX 3EX8A 1DIUA 4KY8A 5CC9A 5HVBA 3OCHA 3SRUX 1DR6A 3F8ZA
chains in the Genus database with same CATH topology
4EIGA 1DG5A 2W9TA 3SRQX 4I13A 1J3JA 1BOZA 1SEJA 1DISA 4GH8A 3F0VX 4XT6A 3CL9A 3JWCA 4P66A 3F0QX 1IA4A 3NU0A 3Q1HA 3JWKA 3FS6A 1DLSA 2W9SA 3EEMA 1RX4A 1PD9A 3KY8A 1S3WA 3FYVX 3NXXA 2CIGA 1KMVA 4QJCA 2QK8A 1DG8A 1U70A 3IRMA 1RC4A 3NRRA 4ELFA 1DG7A 1VJ3A 4I1NA 3IX9A 4CD2A 3K47A 1DYJA 4KL9A 4RGCA 4LEKX 1RA9A 3QL3A 1RH3A 1BZFA 4HOEA 1HFRA 1DRAA 3D80A 1RA8A 3GHVA 3SRRX 2P4GA 4H97A 3RG9A 3DATA 3S3VA 5U26A 1RX6A 4ELGA 3QFXA 4ELBA 3FL9A 4EILA 2C2SA 4H96A 3DRCA 3FQVA 2BLBA 1U71A 2W3WA 4X5IA 3GHCA 3NZ9X 4P68A 4H95A 1RX1A 3NZBX 3NXTA 3JSUA 2W9GA 4FGHA 1DLRA 4ELEA 4KYAA 3FREX 3KJRA 4M2XA 4M6JA 1DYRA 2C2TA 4IXFX 3NZ6X 3HJ3A 4X5GA 5HF2X 5HQYA 3JW3A 4LAHX 4QLGA 3R33A 2DRCA 2FZIA 1PD8A 4QHVA 3CLBA 1AI9A 1M78A 3TQBA 1DRBA 5HI6A 3SA2A 3JWFA 3QLZA 3TD8A 4EJ1A 4M6LA 1DR5A 1DHFA 1E26A 3SR5X 3TQ8A 1DR3A 1KMSA 4M7UA 2W9HA 3OAFA 4M6KA 3JW5A 5HSUA 4XT5A 2W3AA 3IRNA 1RX7A 5HPBA 4HA7A 4XT7A 1KLKA 1CD2A 4PSYA 3UM6A 3QGTA 1RB2A 3SQYX 5JG0X 4H98A 1S3YA 1DHJA 5FDAA 3I8AX 3IROA 3JTWA 1YHOA 3SGYA 5DXVA 4PDJA 1U72A 4KJLA 1M79A 4Q0EA 2XW7A 1JOMA 3IA5A 4HOFA 2B3ZA 4IXGX 2ITHA 5HVEA 3NXYA 1RA1A 1M7AA 3EEKA 5HT4A 1IA3A 4KY4A 1RX9A 1DRHA 3DL6A 3SAIA 4FHBA 3FY8X 3ZPGA 3SA1A 3ZPCA 3D84X 3NXVA 2ANQA 1ZDRA 3DFRA 4PSTA 1JUVA 2HM9A 1TDRA 4X5JA 3FL8A 3FY9X 4M7VA 5HQZA 5DFRA 4KM0A 3F91A 4KBNA 1PDBA 4XT4A 2D5NA 3QYOA 1RX8A 3INVA 4DP3A 1S3UA 1RG7A 2H2QA 3QYLA 1OHKA 4QLFA 3N0HA 3TQAA 3ROAA 5ECXA 5E8QA 2BL9A 4Q67A 3FQ0A 4KFJA 3K74A 4P3RA 3SRWX 1LY4A 4KAKA 3NZCX 6DFRA 5HT5A 2HQPA 1LUDA 1JOLA 3SH2A 4XT8A 1DDSA 1RE7A 5CCCA 3GYFA 1RA3A 3FRFX 1DR4A 4OSGA 3DL5A 4XE6X 1D1GA 3FRDX 1RD7A 4DDRA 1S3VA 2BLCA 2L28A 4QJZD 3F0UX 1HFPA 3FQZA 3DGAA 3VCOA 2FZHA 4Q6AA 1AOEA 3JWMA 4PTJA 2DHFA 4DFRA 2FZJA 3QLXA 2KGKA 1DHIA 3FQCA 3M09A 5HUIA 4KLXA 3QL0A 2JYBA 3GI2A 4ELHA 1RX5A 3K2HA 3NXOA 3QG2A 4PSSA 2W3BA 4Q0DA 4G3MA 3CSEA 3NTZA 2D0KA 5EAJA 2INQA 5U27A 3KFYA 3EELA 4KJKA 1DREA 1IA2A 1RX3A 1J3IA 3RO9A 3UM8A 4NX6A 7DFRA 3I3RA 4KNEA 3L3RA 3QLRA 2AZNA 3DG8A 3LG4A 1J3KA 3M08A 3S7AA 4HOGA 3TQ9A 1DR1A 5ECCA 3QLYA 4LAGX 4DPHA 4QI9A 4KEBA 4TU5X 3IA4A 2O7PA 4OR7A 2BLAA 2OIPA 4X5HA 1LY3A 1RB3A 4ECKA 4XECX 3QLSA 3F8YA 2G6VA 1IA1A 1HFQA 4IXED 1RA2A 3F0BX 5HF0X 1MVSA 4XRBA 3KJSA 3SRSX 1DR7A 3JVXA 2OBCA 3E0BA 5JA3A 1DF7A 4HA9A 1QZFA 1RX2A 1DYIA 3K45A 4G8ZX 1DYHA 2ANOA 2CD2A 1MVTA 2LF1A 4PTHA 4FGGA 3F0XX 4P3QA 3NXRA 3QLWA 2ZZAA 4KJJA 1OHJA 4LAEX 4DPDA 3FRAX 3UM5A 4NX7A 3FQFA 3GHWA 3DAUA 1VDRA 1AO8A 2W3VA 3KGYA 4EIZA 2W3MA 1DR2A 8DFRA 3FYWX 2HXVA 3NZAX 5HSRA 1CZ3A 3EIGA 3HBBA 3S9UA 1DAJA 3CD2A 3FQOA 3NZDA 1DRFA 1RF7A 2GD9A 4G95A 4X5FA 3EEJA 4QLEA 3F0SX 1DDRA 4KD7A 4KM2A 3FRBX 3EX8A 1DIUA 4KY8A 5CC9A 5HVBA 3OCHA 3SRUX 1DR6A 3F8ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EIG A;  1DG5 A;  2W9T A;  3SRQ X;  4I13 A;  1J3J A;  1BOZ A;  1SEJ A;  1DIS A;  4GH8 A;  3F0V X;  4XT6 A;  3CL9 A;  3JWC A;  4P66 A;  3F0Q X;  1IA4 A;  3NU0 A;  3Q1H A;  3JWK A;  3FS6 A;  1DLS A;  2W9S A;  3EEM A;  1RX4 A;  1PD9 A;  3KY8 A;  1S3W A;  3FYV X;  3NXX A;  2CIG A;  1KMV A;  4QJC A;  2QK8 A;  1DG8 A;  1U70 A;  3IRM A;  1RC4 A;  3NRR A;  4ELF A;  1DG7 A;  1VJ3 A;  4I1N A;  3IX9 A;  4CD2 A;  3K47 A;  1DYJ A;  4KL9 A;  4RGC A;  4LEK X;  1RA9 A;  3QL3 A;  1RH3 A;  1BZF A;  4HOE A;  1HFR A;  1DRA A;  3D80 A;  1RA8 A;  3GHV A;  3SRR X;  2P4G A;  4H97 A;  3RG9 A;  3DAT A;  3S3V A;  5U26 A;  1RX6 A;  4ELG A;  3QFX A;  4ELB A;  3FL9 A;  4EIL A;  2C2S A;  4H96 A;  3DRC A;  3FQV A;  2BLB A;  1U71 A;  2W3W A;  4X5I A;  3GHC A;  3NZ9 X;  4P68 A;  4H95 A;  1RX1 A;  3NZB X;  3NXT A;  3JSU A;  2W9G A;  4FGH A;  1DLR A;  4ELE A;  4KYA A;  3FRE X;  3KJR A;  4M2X A;  4M6J A;  1DYR A;  2C2T A;  4IXF X;  3NZ6 X;  3HJ3 A;  4X5G A;  5HF2 X;  5HQY A;  3JW3 A;  4LAH X;  4QLG A;  3R33 A;  2DRC A;  2FZI A;  1PD8 A;  4QHV A;  3CLB A;  1AI9 A;  1M78 A;  3TQB A;  1DRB A;  5HI6 A;  3SA2 A;  3JWF A;  3QLZ A;  3TD8 A;  4EJ1 A;  4M6L A;  1DR5 A;  1DHF A;  1E26 A;  3SR5 X;  3TQ8 A;  1DR3 A;  1KMS A;  4M7U A;  2W9H A;  3OAF A;  4M6K A;  3JW5 A;  5HSU A;  4XT5 A;  2W3A A;  3IRN A;  1RX7 A;  5HPB A;  4HA7 A;  4XT7 A;  1KLK A;  1CD2 A;  4PSY A;  3UM6 A;  3QGT A;  1RB2 A;  3SQY X;  5JG0 X;  4H98 A;  1S3Y A;  1DHJ A;  5FDA A;  3I8A X;  3IRO A;  3JTW A;  1YHO A;  3SGY A;  5DXV A;  4PDJ A;  1U72 A;  4KJL A;  1M79 A;  4Q0E A;  2XW7 A;  1JOM A;  3IA5 A;  4HOF A;  2B3Z A;  4IXG X;  2ITH A;  5HVE A;  3NXY A;  1RA1 A;  1M7A A;  3EEK A;  5HT4 A;  1IA3 A;  4KY4 A;  1RX9 A;  1DRH A;  3DL6 A;  3SAI A;  4FHB A;  3FY8 X;  3ZPG A;  3SA1 A;  3ZPC A;  3D84 X;  3NXV A;  2ANQ A;  1ZDR A;  3DFR A;  4PST A;  1JUV A;  2HM9 A;  1TDR A;  4X5J A;  3FL8 A;  3FY9 X;  4M7V A;  5HQZ A;  5DFR A;  4KM0 A;  3F91 A;  4KBN A;  1PDB A;  4XT4 A;  2D5N A;  3QYO A;  1RX8 A;  3INV A;  4DP3 A;  1S3U A;  1RG7 A;  2H2Q A;  3QYL A;  1OHK A;  4QLF A;  3N0H A;  3TQA A;  3ROA A;  5ECX A;  5E8Q A;  2BL9 A;  4Q67 A;  3FQ0 A;  4KFJ A;  3K74 A;  4P3R A;  3SRW X;  1LY4 A;  4KAK A;  3NZC X;  6DFR A;  5HT5 A;  2HQP A;  1LUD A;  1JOL A;  3SH2 A;  4XT8 A;  1DDS A;  1RE7 A;  5CCC A;  3GYF A;  1RA3 A;  3FRF X;  1DR4 A;  4OSG A;  3DL5 A;  4XE6 X;  1D1G A;  3FRD X;  1RD7 A;  4DDR A;  1S3V A;  2BLC A;  2L28 A;  4QJZ D;  3F0U X;  1HFP A;  3FQZ A;  3DGA A;  3VCO A;  2FZH A;  4Q6A A;  1AOE A;  3JWM A;  4PTJ A;  2DHF A;  4DFR A;  2FZJ A;  3QLX A;  2KGK A;  1DHI A;  3FQC A;  3M09 A;  5HUI A;  4KLX A;  3QL0 A;  2JYB A;  3GI2 A;  4ELH A;  1RX5 A;  3K2H A;  3NXO A;  3QG2 A;  4PSS A;  2W3B A;  4Q0D A;  4G3M A;  3CSE A;  3NTZ A;  2D0K A;  5EAJ A;  2INQ A;  5U27 A;  3KFY A;  3EEL A;  4KJK A;  1DRE A;  1IA2 A;  1RX3 A;  1J3I A;  3RO9 A;  3UM8 A;  4NX6 A;  7DFR A;  3I3R A;  4KNE A;  3L3R A;  3QLR A;  2AZN A;  3DG8 A;  3LG4 A;  1J3K A;  3M08 A;  3S7A A;  4HOG A;  3TQ9 A;  1DR1 A;  5ECC A;  3QLY A;  4LAG X;  4DPH A;  4QI9 A;  4KEB A;  4TU5 X;  3IA4 A;  2O7P A;  4OR7 A;  2BLA A;  2OIP A;  4X5H A;  1LY3 A;  1RB3 A;  4ECK A;  4XEC X;  3QLS A;  3F8Y A;  2G6V A;  1IA1 A;  1HFQ A;  4IXE D;  1RA2 A;  3F0B X;  5HF0 X;  1MVS A;  4XRB A;  3KJS A;  3SRS X;  1DR7 A;  3JVX A;  2OBC A;  3E0B A;  5JA3 A;  1DF7 A;  4HA9 A;  1QZF A;  1RX2 A;  1DYI A;  3K45 A;  4G8Z X;  1DYH A;  2ANO A;  2CD2 A;  1MVT A;  2LF1 A;  4PTH A;  4FGG A;  3F0X X;  4P3Q A;  3NXR A;  3QLW A;  2ZZA A;  4KJJ A;  1OHJ A;  4LAE X;  4DPD A;  3FRA X;  3UM5 A;  4NX7 A;  3FQF A;  3GHW A;  3DAU A;  1VDR A;  1AO8 A;  2W3V A;  3KGY A;  4EIZ A;  2W3M A;  1DR2 A;  8DFR A;  3FYW X;  2HXV A;  3NZA X;  5HSR A;  1CZ3 A;  3EIG A;  3HBB A;  3S9U A;  1DAJ A;  3CD2 A;  3FQO A;  3NZD A;  1DRF A;  1RF7 A;  2GD9 A;  4G95 A;  4X5F A;  3EEJ A;  4QLE A;  3F0S X;  1DDR A;  4KD7 A;  4KM2 A;  3FRB X;  3EX8 A;  1DIU A;  4KY8 A;  5CC9 A;  5HVB A;  3OCH A;  3SRU X;  1DR6 A;  3F8Z A; 
#chains in the Genus database with same CATH topology
 4EIG A;  1DG5 A;  2W9T A;  3SRQ X;  4I13 A;  1J3J A;  1BOZ A;  1SEJ A;  1DIS A;  4GH8 A;  3F0V X;  4XT6 A;  3CL9 A;  3JWC A;  4P66 A;  3F0Q X;  1IA4 A;  3NU0 A;  3Q1H A;  3JWK A;  3FS6 A;  1DLS A;  2W9S A;  3EEM A;  1RX4 A;  1PD9 A;  3KY8 A;  1S3W A;  3FYV X;  3NXX A;  2CIG A;  1KMV A;  4QJC A;  2QK8 A;  1DG8 A;  1U70 A;  3IRM A;  1RC4 A;  3NRR A;  4ELF A;  1DG7 A;  1VJ3 A;  4I1N A;  3IX9 A;  4CD2 A;  3K47 A;  1DYJ A;  4KL9 A;  4RGC A;  4LEK X;  1RA9 A;  3QL3 A;  1RH3 A;  1BZF A;  4HOE A;  1HFR A;  1DRA A;  3D80 A;  1RA8 A;  3GHV A;  3SRR X;  2P4G A;  4H97 A;  3RG9 A;  3DAT A;  3S3V A;  5U26 A;  1RX6 A;  4ELG A;  3QFX A;  4ELB A;  3FL9 A;  4EIL A;  2C2S A;  4H96 A;  3DRC A;  3FQV A;  2BLB A;  1U71 A;  2W3W A;  4X5I A;  3GHC A;  3NZ9 X;  4P68 A;  4H95 A;  1RX1 A;  3NZB X;  3NXT A;  3JSU A;  2W9G A;  4FGH A;  1DLR A;  4ELE A;  4KYA A;  3FRE X;  3KJR A;  4M2X A;  4M6J A;  1DYR A;  2C2T A;  4IXF X;  3NZ6 X;  3HJ3 A;  4X5G A;  5HF2 X;  5HQY A;  3JW3 A;  4LAH X;  4QLG A;  3R33 A;  2DRC A;  2FZI A;  1PD8 A;  4QHV A;  3CLB A;  1AI9 A;  1M78 A;  3TQB A;  1DRB A;  5HI6 A;  3SA2 A;  3JWF A;  3QLZ A;  3TD8 A;  4EJ1 A;  4M6L A;  1DR5 A;  1DHF A;  1E26 A;  3SR5 X;  3TQ8 A;  1DR3 A;  1KMS A;  4M7U A;  2W9H A;  3OAF A;  4M6K A;  3JW5 A;  5HSU A;  4XT5 A;  2W3A A;  3IRN A;  1RX7 A;  5HPB A;  4HA7 A;  4XT7 A;  1KLK A;  1CD2 A;  4PSY A;  3UM6 A;  3QGT A;  1RB2 A;  3SQY X;  5JG0 X;  4H98 A;  1S3Y A;  1DHJ A;  5FDA A;  3I8A X;  3IRO A;  3JTW A;  1YHO A;  3SGY A;  5DXV A;  4PDJ A;  1U72 A;  4KJL A;  1M79 A;  4Q0E A;  2XW7 A;  1JOM A;  3IA5 A;  4HOF A;  2B3Z A;  4IXG X;  2ITH A;  5HVE A;  3NXY A;  1RA1 A;  1M7A A;  3EEK A;  5HT4 A;  1IA3 A;  4KY4 A;  1RX9 A;  1DRH A;  3DL6 A;  3SAI A;  4FHB A;  3FY8 X;  3ZPG A;  3SA1 A;  3ZPC A;  3D84 X;  3NXV A;  2ANQ A;  1ZDR A;  3DFR A;  4PST A;  1JUV A;  2HM9 A;  1TDR A;  4X5J A;  3FL8 A;  3FY9 X;  4M7V A;  5HQZ A;  5DFR A;  4KM0 A;  3F91 A;  4KBN A;  1PDB A;  4XT4 A;  2D5N A;  3QYO A;  1RX8 A;  3INV A;  4DP3 A;  1S3U A;  1RG7 A;  2H2Q A;  3QYL A;  1OHK A;  4QLF A;  3N0H A;  3TQA A;  3ROA A;  5ECX A;  5E8Q A;  2BL9 A;  4Q67 A;  3FQ0 A;  4KFJ A;  3K74 A;  4P3R A;  3SRW X;  1LY4 A;  4KAK A;  3NZC X;  6DFR A;  5HT5 A;  2HQP A;  1LUD A;  1JOL A;  3SH2 A;  4XT8 A;  1DDS A;  1RE7 A;  5CCC A;  3GYF A;  1RA3 A;  3FRF X;  1DR4 A;  4OSG A;  3DL5 A;  4XE6 X;  1D1G A;  3FRD X;  1RD7 A;  4DDR A;  1S3V A;  2BLC A;  2L28 A;  4QJZ D;  3F0U X;  1HFP A;  3FQZ A;  3DGA A;  3VCO A;  2FZH A;  4Q6A A;  1AOE A;  3JWM A;  4PTJ A;  2DHF A;  4DFR A;  2FZJ A;  3QLX A;  2KGK A;  1DHI A;  3FQC A;  3M09 A;  5HUI A;  4KLX A;  3QL0 A;  2JYB A;  3GI2 A;  4ELH A;  1RX5 A;  3K2H A;  3NXO A;  3QG2 A;  4PSS A;  2W3B A;  4Q0D A;  4G3M A;  3CSE A;  3NTZ A;  2D0K A;  5EAJ A;  2INQ A;  5U27 A;  3KFY A;  3EEL A;  4KJK A;  1DRE A;  1IA2 A;  1RX3 A;  1J3I A;  3RO9 A;  3UM8 A;  4NX6 A;  7DFR A;  3I3R A;  4KNE A;  3L3R A;  3QLR A;  2AZN A;  3DG8 A;  3LG4 A;  1J3K A;  3M08 A;  3S7A A;  4HOG A;  3TQ9 A;  1DR1 A;  5ECC A;  3QLY A;  4LAG X;  4DPH A;  4QI9 A;  4KEB A;  4TU5 X;  3IA4 A;  2O7P A;  4OR7 A;  2BLA A;  2OIP A;  4X5H A;  1LY3 A;  1RB3 A;  4ECK A;  4XEC X;  3QLS A;  3F8Y A;  2G6V A;  1IA1 A;  1HFQ A;  4IXE D;  1RA2 A;  3F0B X;  5HF0 X;  1MVS A;  4XRB A;  3KJS A;  3SRS X;  1DR7 A;  3JVX A;  2OBC A;  3E0B A;  5JA3 A;  1DF7 A;  4HA9 A;  1QZF A;  1RX2 A;  1DYI A;  3K45 A;  4G8Z X;  1DYH A;  2ANO A;  2CD2 A;  1MVT A;  2LF1 A;  4PTH A;  4FGG A;  3F0X X;  4P3Q A;  3NXR A;  3QLW A;  2ZZA A;  4KJJ A;  1OHJ A;  4LAE X;  4DPD A;  3FRA X;  3UM5 A;  4NX7 A;  3FQF A;  3GHW A;  3DAU A;  1VDR A;  1AO8 A;  2W3V A;  3KGY A;  4EIZ A;  2W3M A;  1DR2 A;  8DFR A;  3FYW X;  2HXV A;  3NZA X;  5HSR A;  1CZ3 A;  3EIG A;  3HBB A;  3S9U A;  1DAJ A;  3CD2 A;  3FQO A;  3NZD A;  1DRF A;  1RF7 A;  2GD9 A;  4G95 A;  4X5F A;  3EEJ A;  4QLE A;  3F0S X;  1DDR A;  4KD7 A;  4KM2 A;  3FRB X;  3EX8 A;  1DIU A;  4KY8 A;  5CC9 A;  5HVB A;  3OCH A;  3SRU X;  1DR6 A;  3F8Z A; 
#chains in the Genus database with same CATH homology
 4EIG A;  1DG5 A;  2W9T A;  3SRQ X;  4I13 A;  1J3J A;  1BOZ A;  1SEJ A;  1DIS A;  4GH8 A;  3F0V X;  4XT6 A;  3CL9 A;  3JWC A;  4P66 A;  3F0Q X;  1IA4 A;  3NU0 A;  3Q1H A;  3JWK A;  3FS6 A;  1DLS A;  2W9S A;  3EEM A;  1RX4 A;  1PD9 A;  3KY8 A;  1S3W A;  3FYV X;  3NXX A;  2CIG A;  1KMV A;  4QJC A;  2QK8 A;  1DG8 A;  1U70 A;  3IRM A;  1RC4 A;  3NRR A;  4ELF A;  1DG7 A;  1VJ3 A;  4I1N A;  3IX9 A;  4CD2 A;  3K47 A;  1DYJ A;  4KL9 A;  4RGC A;  4LEK X;  1RA9 A;  3QL3 A;  1RH3 A;  1BZF A;  4HOE A;  1HFR A;  1DRA A;  3D80 A;  1RA8 A;  3GHV A;  3SRR X;  2P4G A;  4H97 A;  3RG9 A;  3DAT A;  3S3V A;  5U26 A;  1RX6 A;  4ELG A;  3QFX A;  4ELB A;  3FL9 A;  4EIL A;  2C2S A;  4H96 A;  3DRC A;  3FQV A;  2BLB A;  1U71 A;  2W3W A;  4X5I A;  3GHC A;  3NZ9 X;  4P68 A;  4H95 A;  1RX1 A;  3NZB X;  3NXT A;  3JSU A;  2W9G A;  4FGH A;  1DLR A;  4ELE A;  4KYA A;  3FRE X;  3KJR A;  4M2X A;  4M6J A;  1DYR A;  2C2T A;  4IXF X;  3NZ6 X;  3HJ3 A;  4X5G A;  5HF2 X;  5HQY A;  3JW3 A;  4LAH X;  4QLG A;  3R33 A;  2DRC A;  2FZI A;  1PD8 A;  4QHV A;  3CLB A;  1AI9 A;  1M78 A;  3TQB A;  1DRB A;  5HI6 A;  3SA2 A;  3JWF A;  3QLZ A;  3TD8 A;  4EJ1 A;  4M6L A;  1DR5 A;  1DHF A;  1E26 A;  3SR5 X;  3TQ8 A;  1DR3 A;  1KMS A;  4M7U A;  2W9H A;  3OAF A;  4M6K A;  3JW5 A;  5HSU A;  4XT5 A;  2W3A A;  3IRN A;  1RX7 A;  5HPB A;  4HA7 A;  4XT7 A;  1KLK A;  1CD2 A;  4PSY A;  3UM6 A;  3QGT A;  1RB2 A;  3SQY X;  5JG0 X;  4H98 A;  1S3Y A;  1DHJ A;  5FDA A;  3I8A X;  3IRO A;  3JTW A;  1YHO A;  3SGY A;  5DXV A;  4PDJ A;  1U72 A;  4KJL A;  1M79 A;  4Q0E A;  2XW7 A;  1JOM A;  3IA5 A;  4HOF A;  2B3Z A;  4IXG X;  2ITH A;  5HVE A;  3NXY A;  1RA1 A;  1M7A A;  3EEK A;  5HT4 A;  1IA3 A;  4KY4 A;  1RX9 A;  1DRH A;  3DL6 A;  3SAI A;  4FHB A;  3FY8 X;  3ZPG A;  3SA1 A;  3ZPC A;  3D84 X;  3NXV A;  2ANQ A;  1ZDR A;  3DFR A;  4PST A;  1JUV A;  2HM9 A;  1TDR A;  4X5J A;  3FL8 A;  3FY9 X;  4M7V A;  5HQZ A;  5DFR A;  4KM0 A;  3F91 A;  4KBN A;  1PDB A;  4XT4 A;  2D5N A;  3QYO A;  1RX8 A;  3INV A;  4DP3 A;  1S3U A;  1RG7 A;  2H2Q A;  3QYL A;  1OHK A;  4QLF A;  3N0H A;  3TQA A;  3ROA A;  5ECX A;  5E8Q A;  2BL9 A;  4Q67 A;  3FQ0 A;  4KFJ A;  3K74 A;  4P3R A;  3SRW X;  1LY4 A;  4KAK A;  3NZC X;  6DFR A;  5HT5 A;  2HQP A;  1LUD A;  1JOL A;  3SH2 A;  4XT8 A;  1DDS A;  1RE7 A;  5CCC A;  3GYF A;  1RA3 A;  3FRF X;  1DR4 A;  4OSG A;  3DL5 A;  4XE6 X;  1D1G A;  3FRD X;  1RD7 A;  4DDR A;  1S3V A;  2BLC A;  2L28 A;  4QJZ D;  3F0U X;  1HFP A;  3FQZ A;  3DGA A;  3VCO A;  2FZH A;  4Q6A A;  1AOE A;  3JWM A;  4PTJ A;  2DHF A;  4DFR A;  2FZJ A;  3QLX A;  2KGK A;  1DHI A;  3FQC A;  3M09 A;  5HUI A;  4KLX A;  3QL0 A;  2JYB A;  3GI2 A;  4ELH A;  1RX5 A;  3K2H A;  3NXO A;  3QG2 A;  4PSS A;  2W3B A;  4Q0D A;  4G3M A;  3CSE A;  3NTZ A;  2D0K A;  5EAJ A;  2INQ A;  5U27 A;  3KFY A;  3EEL A;  4KJK A;  1DRE A;  1IA2 A;  1RX3 A;  1J3I A;  3RO9 A;  3UM8 A;  4NX6 A;  7DFR A;  3I3R A;  4KNE A;  3L3R A;  3QLR A;  2AZN A;  3DG8 A;  3LG4 A;  1J3K A;  3M08 A;  3S7A A;  4HOG A;  3TQ9 A;  1DR1 A;  5ECC A;  3QLY A;  4LAG X;  4DPH A;  4QI9 A;  4KEB A;  4TU5 X;  3IA4 A;  2O7P A;  4OR7 A;  2BLA A;  2OIP A;  4X5H A;  1LY3 A;  1RB3 A;  4ECK A;  4XEC X;  3QLS A;  3F8Y A;  2G6V A;  1IA1 A;  1HFQ A;  4IXE D;  1RA2 A;  3F0B X;  5HF0 X;  1MVS A;  4XRB A;  3KJS A;  3SRS X;  1DR7 A;  3JVX A;  2OBC A;  3E0B A;  5JA3 A;  1DF7 A;  4HA9 A;  1QZF A;  1RX2 A;  1DYI A;  3K45 A;  4G8Z X;  1DYH A;  2ANO A;  2CD2 A;  1MVT A;  2LF1 A;  4PTH A;  4FGG A;  3F0X X;  4P3Q A;  3NXR A;  3QLW A;  2ZZA A;  4KJJ A;  1OHJ A;  4LAE X;  4DPD A;  3FRA X;  3UM5 A;  4NX7 A;  3FQF A;  3GHW A;  3DAU A;  1VDR A;  1AO8 A;  2W3V A;  3KGY A;  4EIZ A;  2W3M A;  1DR2 A;  8DFR A;  3FYW X;  2HXV A;  3NZA X;  5HSR A;  1CZ3 A;  3EIG A;  3HBB A;  3S9U A;  1DAJ A;  3CD2 A;  3FQO A;  3NZD A;  1DRF A;  1RF7 A;  2GD9 A;  4G95 A;  4X5F A;  3EEJ A;  4QLE A;  3F0S X;  1DDR A;  4KD7 A;  4KM2 A;  3FRB X;  3EX8 A;  1DIU A;  4KY8 A;  5CC9 A;  5HVB A;  3OCH A;  3SRU X;  1DR6 A;  3F8Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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