1RX2A

Dihydrofolate reductase (e.c.1.5.1.3) complexed with with folate and nicotinamide adenine dinucleotide phosphate (oxidized form)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Escherichia coli
publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rx2A00
3FREX 2W9SA 3QG2A 1RX7A 1RX1A 4X5GA 1DREA 4XRBA 1S3UA 4M7UA 4OR7A 4IXFX 3DFRA 2W9TA 1RX5A 1RX3A 3FY8X 4LAEX 3FQVA 4HA9A 4H96A 4DPHA 1BZFA 3CD2A 3KY8A 2HM9A 3SRUX 3NRRA 3DRCA 2ITHA 4KL9A 4OSGA 5CCCA 4X5IA 2H2QA 3DATA 1DG8A 2HQPA 4G3MA 4QLEA 2ANOA 1DHIA 3NXXA 1CD2A 1DHJA 3QFXA 2W9HA 1DDRA 3VCOA 3D80A 3KFYA 1IA1A 3SRSX 4P68A 1DR6A 5HSUA 1DYIA 2W3AA 5HVBA 4XT4A 2BL9A 5HF0X 3QLZA 4X5JA 4KJLA 3JWCA 3F91A 4KY4A 3UM6A 3F0UX 3NZCX 3F8ZA 3FRDX 4XT5A 2D0KA 4EJ1A 2XW7A 4PSTA 1AO8A 3UM8A 4QJCA 4DPDA 4TU5X 1RA2A 4KJJA 6DFRA 1PD9A 1U71A 1IA3A 3OCHA 3M08A 4KBNA 4H98A 1DRBA 3NZDA 3DL5A 3TQBA 1RX6A 3S3VA 2CIGA 3F0QX 1J3IA 1DR5A 3QL0A 1RX2A 5DXVA 5HT5A 2C2TA 4KNEA 4H95A 3FQCA 5ECCA 4HOFA 3JWKA 3ZPCA 5HPBA 3QLWA 3FQ0A 4P3QA 4GH8A 3ZPGA 4KYAA 3EEJA 3FQFA 4QLGA 2CD2A 1RC4A 1PD8A 3K45A 2FZJA 1DR2A 1M78A 3JWMA 3DG8A 1ZDRA 4H97A 1MVSA 4PDJA 4X5HA 4PTHA 3EELA 2BLAA 1HFRA 3K74A 3LG4A 3QYLA 4M6KA 1DYJA 4RGCA 4IXGX 1TDRA 1RF7A 1JOLA 3FS6A 3JSUA 5HVEA 3SRQX 4P3RA 3NTZA 1DRFA 2INQA 4Q0EA 3QLRA 4DFRA 1HFQA 1RA9A 2OIPA 3FQOA 3GHVA 4NX7A 5E8QA 2C2SA 1RH3A 1VDRA 2AZNA 4M2XA 3JWFA 3NZAX 3I3RA 4ELBA 2W9GA 1DR3A 2G6VA 1SEJA 1YHOA 3L3RA 4G8ZX 3RO9A 3SQYX 5HQYA 1RD7A 4HOEA 1D1GA 4M7VA 2L28A 3GYFA 5FDAA 5HF2X 3NU0A 1IA2A 4KJKA 3D84X 3I8AX 4FGHA 3HBBA 2KGKA 3EEKA 1RX9A 3F0XX 3CSEA 3DL6A 3RG9A 4P66A 4KM0A 4ELGA 3N0HA 5HUIA 3FQZA 3TQ8A 3FL9A 4QLFA 4XT8A 3JW5A 1RX4A 1RX8A 1LY4A 3KJRA 3NXOA 1KMVA 2ZZAA 1J3KA 3KJSA 4KM2A 1RB2A 1J3JA 3IX9A 2QK8A 2FZHA 4KD7A 4EIZA 2HXVA 4ECKA 2DRCA 1RA8A 3SA1A 3TD8A 2BLBA 3GI2A 3SRRX 2DHFA 4QHVA 3R33A 3JTWA 3CLBA 2W3WA 3QLYA 4EILA 3EX8A 1RA3A 4LAHX 3FRBX 1DAJA 4DDRA 5ECXA 3FY9X 3DAUA 4Q67A 3SH2A 3UM5A 3EIGA 1MVTA 3SRWX 2P4GA 4LAGX 3FRFX 5DFRA 2JYBA 3FYWX 4LEKX 3QL3A 4KY8A 7DFRA 8DFRA 3JW3A 2FZIA 3F0BX 1OHKA 1KMSA 1JUVA 3IRMA 5HSRA 1U70A 4KAKA 3QLXA 1AI9A 4ELEA 5HI6A 3SGYA 3FYVX 5HQZA 3F8YA 4QI9A 4KLXA 3ROAA 5CC9A 3EEMA 1RG7A 4HA7A 1M7AA 4X5FA 3S9UA 2LF1A 3F0VX 3K47A 4EIGA 3QGTA 4XT7A 3K2HA 3QYOA 4XECX 4KFJA 3SR5X 1DYRA 4KEBA 3NXTA 5EAJA 5U26A 3TQAA 3NXVA 4NX6A 1LUDA 4G95A 4ELFA 4QJZD 1DG7A 2BLCA 3NXRA 3Q1HA 4FGGA 3SAIA 1BOZA 1S3YA 3IRNA 4I1NA 5JA3A 4Q0DA 3IA5A 4DP3A 3INVA 3DGAA 5HT4A 3E0BA 3S7AA 1DIUA 4IXED 1RE7A 3NZ6X 1LY3A 3CL9A 1DG5A 1DRAA 4PTJA 1DHFA 1DF7A 3OAFA 1RB3A 1S3VA 5U27A 4XE6X 2W3VA 2ANQA 3NZ9X 3IROA 1IA4A 3KGYA 3HJ3A 1DR7A 2OBCA 4HOGA 2W3MA 1JOMA 2B3ZA 1DISA 4I13A 4CD2A 3QLSA 2GD9A 1PDBA 3GHCA 1CZ3A 3TQ9A 2D5NA 2O7PA 1VJ3A 1QZFA 1DR1A 3F0SX 4ELHA 1DLRA 4FHBA 3NXYA 1DYHA 1DR4A 3M09A 3SA2A 4Q6AA 4M6LA 1M79A 1RA1A 3FRAX 3NZBX 1DRHA 3GHWA 1U72A 3IA4A 1HFPA 2W3BA 5JG0X 1DDSA 1OHJA 4PSYA 4M6JA 1AOEA 1KLKA 1S3WA 4XT6A 4PSSA 1DLSA 1E26A 3JVXA 3FL8A
chains in the Genus database with same CATH superfamily
3FREX 2W9SA 3QG2A 1RX7A 1RX1A 4X5GA 1DREA 4XRBA 1S3UA 4M7UA 4OR7A 4IXFX 3DFRA 2W9TA 1RX5A 1RX3A 3FY8X 4LAEX 3FQVA 4HA9A 4H96A 4DPHA 1BZFA 3CD2A 3KY8A 2HM9A 3SRUX 3NRRA 3DRCA 2ITHA 4KL9A 4OSGA 5CCCA 4X5IA 2H2QA 3DATA 1DG8A 2HQPA 4G3MA 4QLEA 2ANOA 1DHIA 3NXXA 1CD2A 1DHJA 3QFXA 2W9HA 1DDRA 3VCOA 3D80A 3KFYA 1IA1A 3SRSX 4P68A 1DR6A 5HSUA 1DYIA 2W3AA 5HVBA 4XT4A 2BL9A 5HF0X 3QLZA 4X5JA 4KJLA 3JWCA 3F91A 4KY4A 3UM6A 3F0UX 3NZCX 3F8ZA 3FRDX 4XT5A 2D0KA 4EJ1A 2XW7A 4PSTA 1AO8A 3UM8A 4QJCA 4DPDA 4TU5X 1RA2A 4KJJA 6DFRA 1PD9A 1U71A 1IA3A 3OCHA 3M08A 4KBNA 4H98A 1DRBA 3NZDA 3DL5A 3TQBA 1RX6A 3S3VA 2CIGA 3F0QX 1J3IA 1DR5A 3QL0A 1RX2A 5DXVA 5HT5A 2C2TA 4KNEA 4H95A 3FQCA 5ECCA 4HOFA 3JWKA 3ZPCA 5HPBA 3QLWA 3FQ0A 4P3QA 4GH8A 3ZPGA 4KYAA 3EEJA 3FQFA 4QLGA 2CD2A 1RC4A 1PD8A 3K45A 2FZJA 1DR2A 1M78A 3JWMA 3DG8A 1ZDRA 4H97A 1MVSA 4PDJA 4X5HA 4PTHA 3EELA 2BLAA 1HFRA 3K74A 3LG4A 3QYLA 4M6KA 1DYJA 4RGCA 4IXGX 1TDRA 1RF7A 1JOLA 3FS6A 3JSUA 5HVEA 3SRQX 4P3RA 3NTZA 1DRFA 2INQA 4Q0EA 3QLRA 4DFRA 1HFQA 1RA9A 2OIPA 3FQOA 3GHVA 4NX7A 5E8QA 2C2SA 1RH3A 1VDRA 2AZNA 4M2XA 3JWFA 3NZAX 3I3RA 4ELBA 2W9GA 1DR3A 2G6VA 1SEJA 1YHOA 3L3RA 4G8ZX 3RO9A 3SQYX 5HQYA 1RD7A 4HOEA 1D1GA 4M7VA 2L28A 3GYFA 5FDAA 5HF2X 3NU0A 1IA2A 4KJKA 3D84X 3I8AX 4FGHA 3HBBA 2KGKA 3EEKA 1RX9A 3F0XX 3CSEA 3DL6A 3RG9A 4P66A 4KM0A 4ELGA 3N0HA 5HUIA 3FQZA 3TQ8A 3FL9A 4QLFA 4XT8A 3JW5A 1RX4A 1RX8A 1LY4A 3KJRA 3NXOA 1KMVA 2ZZAA 1J3KA 3KJSA 4KM2A 1RB2A 1J3JA 3IX9A 2QK8A 2FZHA 4KD7A 4EIZA 2HXVA 4ECKA 2DRCA 1RA8A 3SA1A 3TD8A 2BLBA 3GI2A 3SRRX 2DHFA 4QHVA 3R33A 3JTWA 3CLBA 2W3WA 3QLYA 4EILA 3EX8A 1RA3A 4LAHX 3FRBX 1DAJA 4DDRA 5ECXA 3FY9X 3DAUA 4Q67A 3SH2A 3UM5A 3EIGA 1MVTA 3SRWX 2P4GA 4LAGX 3FRFX 5DFRA 2JYBA 3FYWX 4LEKX 3QL3A 4KY8A 7DFRA 8DFRA 3JW3A 2FZIA 3F0BX 1OHKA 1KMSA 1JUVA 3IRMA 5HSRA 1U70A 4KAKA 3QLXA 1AI9A 4ELEA 5HI6A 3SGYA 3FYVX 5HQZA 3F8YA 4QI9A 4KLXA 3ROAA 5CC9A 3EEMA 1RG7A 4HA7A 1M7AA 4X5FA 3S9UA 2LF1A 3F0VX 3K47A 4EIGA 3QGTA 4XT7A 3K2HA 3QYOA 4XECX 4KFJA 3SR5X 1DYRA 4KEBA 3NXTA 5EAJA 5U26A 3TQAA 3NXVA 4NX6A 1LUDA 4G95A 4ELFA 4QJZD 1DG7A 2BLCA 3NXRA 3Q1HA 4FGGA 3SAIA 1BOZA 1S3YA 3IRNA 4I1NA 5JA3A 4Q0DA 3IA5A 4DP3A 3INVA 3DGAA 5HT4A 3E0BA 3S7AA 1DIUA 4IXED 1RE7A 3NZ6X 1LY3A 3CL9A 1DG5A 1DRAA 4PTJA 1DHFA 1DF7A 3OAFA 1RB3A 1S3VA 5U27A 4XE6X 2W3VA 2ANQA 3NZ9X 3IROA 1IA4A 3KGYA 3HJ3A 1DR7A 2OBCA 4HOGA 2W3MA 1JOMA 2B3ZA 1DISA 4I13A 4CD2A 3QLSA 2GD9A 1PDBA 3GHCA 1CZ3A 3TQ9A 2D5NA 2O7PA 1VJ3A 1QZFA 1DR1A 3F0SX 4ELHA 1DLRA 4FHBA 3NXYA 1DYHA 1DR4A 3M09A 3SA2A 4Q6AA 4M6LA 1M79A 1RA1A 3FRAX 3NZBX 1DRHA 3GHWA 1U72A 3IA4A 1HFPA 2W3BA 5JG0X 1DDSA 1OHJA 4PSYA 4M6JA 1AOEA 1KLKA 1S3WA 4XT6A 4PSSA 1DLSA 1E26A 3JVXA 3FL8A
chains in the Genus database with same CATH topology
3FREX 2W9SA 3QG2A 1RX7A 1RX1A 4X5GA 1DREA 4XRBA 1S3UA 4M7UA 4OR7A 4IXFX 3DFRA 2W9TA 1RX5A 1RX3A 3FY8X 4LAEX 3FQVA 4HA9A 4H96A 4DPHA 1BZFA 3CD2A 3KY8A 2HM9A 3SRUX 3NRRA 3DRCA 2ITHA 4KL9A 4OSGA 5CCCA 4X5IA 2H2QA 3DATA 1DG8A 2HQPA 4G3MA 4QLEA 2ANOA 1DHIA 3NXXA 1CD2A 1DHJA 3QFXA 2W9HA 1DDRA 3VCOA 3D80A 3KFYA 1IA1A 3SRSX 4P68A 1DR6A 5HSUA 1DYIA 2W3AA 5HVBA 4XT4A 2BL9A 5HF0X 3QLZA 4X5JA 4KJLA 3JWCA 3F91A 4KY4A 3UM6A 3F0UX 3NZCX 3F8ZA 3FRDX 4XT5A 2D0KA 4EJ1A 2XW7A 4PSTA 1AO8A 3UM8A 4QJCA 4DPDA 4TU5X 1RA2A 4KJJA 6DFRA 1PD9A 1U71A 1IA3A 3OCHA 3M08A 4KBNA 4H98A 1DRBA 3NZDA 3DL5A 3TQBA 1RX6A 3S3VA 2CIGA 3F0QX 1J3IA 1DR5A 3QL0A 1RX2A 5DXVA 5HT5A 2C2TA 4KNEA 4H95A 3FQCA 5ECCA 4HOFA 3JWKA 3ZPCA 5HPBA 3QLWA 3FQ0A 4P3QA 4GH8A 3ZPGA 4KYAA 3EEJA 3FQFA 4QLGA 2CD2A 1RC4A 1PD8A 3K45A 2FZJA 1DR2A 1M78A 3JWMA 3DG8A 1ZDRA 4H97A 1MVSA 4PDJA 4X5HA 4PTHA 3EELA 2BLAA 1HFRA 3K74A 3LG4A 3QYLA 4M6KA 1DYJA 4RGCA 4IXGX 1TDRA 1RF7A 1JOLA 3FS6A 3JSUA 5HVEA 3SRQX 4P3RA 3NTZA 1DRFA 2INQA 4Q0EA 3QLRA 4DFRA 1HFQA 1RA9A 2OIPA 3FQOA 3GHVA 4NX7A 5E8QA 2C2SA 1RH3A 1VDRA 2AZNA 4M2XA 3JWFA 3NZAX 3I3RA 4ELBA 2W9GA 1DR3A 2G6VA 1SEJA 1YHOA 3L3RA 4G8ZX 3RO9A 3SQYX 5HQYA 1RD7A 4HOEA 1D1GA 4M7VA 2L28A 3GYFA 5FDAA 5HF2X 3NU0A 1IA2A 4KJKA 3D84X 3I8AX 4FGHA 3HBBA 2KGKA 3EEKA 1RX9A 3F0XX 3CSEA 3DL6A 3RG9A 4P66A 4KM0A 4ELGA 3N0HA 5HUIA 3FQZA 3TQ8A 3FL9A 4QLFA 4XT8A 3JW5A 1RX4A 1RX8A 1LY4A 3KJRA 3NXOA 1KMVA 2ZZAA 1J3KA 3KJSA 4KM2A 1RB2A 1J3JA 3IX9A 2QK8A 2FZHA 4KD7A 4EIZA 2HXVA 4ECKA 2DRCA 1RA8A 3SA1A 3TD8A 2BLBA 3GI2A 3SRRX 2DHFA 4QHVA 3R33A 3JTWA 3CLBA 2W3WA 3QLYA 4EILA 3EX8A 1RA3A 4LAHX 3FRBX 1DAJA 4DDRA 5ECXA 3FY9X 3DAUA 4Q67A 3SH2A 3UM5A 3EIGA 1MVTA 3SRWX 2P4GA 4LAGX 3FRFX 5DFRA 2JYBA 3FYWX 4LEKX 3QL3A 4KY8A 7DFRA 8DFRA 3JW3A 2FZIA 3F0BX 1OHKA 1KMSA 1JUVA 3IRMA 5HSRA 1U70A 4KAKA 3QLXA 1AI9A 4ELEA 5HI6A 3SGYA 3FYVX 5HQZA 3F8YA 4QI9A 4KLXA 3ROAA 5CC9A 3EEMA 1RG7A 4HA7A 1M7AA 4X5FA 3S9UA 2LF1A 3F0VX 3K47A 4EIGA 3QGTA 4XT7A 3K2HA 3QYOA 4XECX 4KFJA 3SR5X 1DYRA 4KEBA 3NXTA 5EAJA 5U26A 3TQAA 3NXVA 4NX6A 1LUDA 4G95A 4ELFA 4QJZD 1DG7A 2BLCA 3NXRA 3Q1HA 4FGGA 3SAIA 1BOZA 1S3YA 3IRNA 4I1NA 5JA3A 4Q0DA 3IA5A 4DP3A 3INVA 3DGAA 5HT4A 3E0BA 3S7AA 1DIUA 4IXED 1RE7A 3NZ6X 1LY3A 3CL9A 1DG5A 1DRAA 4PTJA 1DHFA 1DF7A 3OAFA 1RB3A 1S3VA 5U27A 4XE6X 2W3VA 2ANQA 3NZ9X 3IROA 1IA4A 3KGYA 3HJ3A 1DR7A 2OBCA 4HOGA 2W3MA 1JOMA 2B3ZA 1DISA 4I13A 4CD2A 3QLSA 2GD9A 1PDBA 3GHCA 1CZ3A 3TQ9A 2D5NA 2O7PA 1VJ3A 1QZFA 1DR1A 3F0SX 4ELHA 1DLRA 4FHBA 3NXYA 1DYHA 1DR4A 3M09A 3SA2A 4Q6AA 4M6LA 1M79A 1RA1A 3FRAX 3NZBX 1DRHA 3GHWA 1U72A 3IA4A 1HFPA 2W3BA 5JG0X 1DDSA 1OHJA 4PSYA 4M6JA 1AOEA 1KLKA 1S3WA 4XT6A 4PSSA 1DLSA 1E26A 3JVXA 3FL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FRE X;  2W9S A;  3QG2 A;  1RX7 A;  1RX1 A;  4X5G A;  1DRE A;  4XRB A;  1S3U A;  4M7U A;  4OR7 A;  4IXF X;  3DFR A;  2W9T A;  1RX5 A;  1RX3 A;  3FY8 X;  4LAE X;  3FQV A;  4HA9 A;  4H96 A;  4DPH A;  1BZF A;  3CD2 A;  3KY8 A;  2HM9 A;  3SRU X;  3NRR A;  3DRC A;  2ITH A;  4KL9 A;  4OSG A;  5CCC A;  4X5I A;  2H2Q A;  3DAT A;  1DG8 A;  2HQP A;  4G3M A;  4QLE A;  2ANO A;  1DHI A;  3NXX A;  1CD2 A;  1DHJ A;  3QFX A;  2W9H A;  1DDR A;  3VCO A;  3D80 A;  3KFY A;  1IA1 A;  3SRS X;  4P68 A;  1DR6 A;  5HSU A;  1DYI A;  2W3A A;  5HVB A;  4XT4 A;  2BL9 A;  5HF0 X;  3QLZ A;  4X5J A;  4KJL A;  3JWC A;  3F91 A;  4KY4 A;  3UM6 A;  3F0U X;  3NZC X;  3F8Z A;  3FRD X;  4XT5 A;  2D0K A;  4EJ1 A;  2XW7 A;  4PST A;  1AO8 A;  3UM8 A;  4QJC A;  4DPD A;  4TU5 X;  1RA2 A;  4KJJ A;  6DFR A;  1PD9 A;  1U71 A;  1IA3 A;  3OCH A;  3M08 A;  4KBN A;  4H98 A;  1DRB A;  3NZD A;  3DL5 A;  3TQB A;  1RX6 A;  3S3V A;  2CIG A;  3F0Q X;  1J3I A;  1DR5 A;  3QL0 A;  1RX2 A;  5DXV A;  5HT5 A;  2C2T A;  4KNE A;  4H95 A;  3FQC A;  5ECC A;  4HOF A;  3JWK A;  3ZPC A;  5HPB A;  3QLW A;  3FQ0 A;  4P3Q A;  4GH8 A;  3ZPG A;  4KYA A;  3EEJ A;  3FQF A;  4QLG A;  2CD2 A;  1RC4 A;  1PD8 A;  3K45 A;  2FZJ A;  1DR2 A;  1M78 A;  3JWM A;  3DG8 A;  1ZDR A;  4H97 A;  1MVS A;  4PDJ A;  4X5H A;  4PTH A;  3EEL A;  2BLA A;  1HFR A;  3K74 A;  3LG4 A;  3QYL A;  4M6K A;  1DYJ A;  4RGC A;  4IXG X;  1TDR A;  1RF7 A;  1JOL A;  3FS6 A;  3JSU A;  5HVE A;  3SRQ X;  4P3R A;  3NTZ A;  1DRF A;  2INQ A;  4Q0E A;  3QLR A;  4DFR A;  1HFQ A;  1RA9 A;  2OIP A;  3FQO A;  3GHV A;  4NX7 A;  5E8Q A;  2C2S A;  1RH3 A;  1VDR A;  2AZN A;  4M2X A;  3JWF A;  3NZA X;  3I3R A;  4ELB A;  2W9G A;  1DR3 A;  2G6V A;  1SEJ A;  1YHO A;  3L3R A;  4G8Z X;  3RO9 A;  3SQY X;  5HQY A;  1RD7 A;  4HOE A;  1D1G A;  4M7V A;  2L28 A;  3GYF A;  5FDA A;  5HF2 X;  3NU0 A;  1IA2 A;  4KJK A;  3D84 X;  3I8A X;  4FGH A;  3HBB A;  2KGK A;  3EEK A;  1RX9 A;  3F0X X;  3CSE A;  3DL6 A;  3RG9 A;  4P66 A;  4KM0 A;  4ELG A;  3N0H A;  5HUI A;  3FQZ A;  3TQ8 A;  3FL9 A;  4QLF A;  4XT8 A;  3JW5 A;  1RX4 A;  1RX8 A;  1LY4 A;  3KJR A;  3NXO A;  1KMV A;  2ZZA A;  1J3K A;  3KJS A;  4KM2 A;  1RB2 A;  1J3J A;  3IX9 A;  2QK8 A;  2FZH A;  4KD7 A;  4EIZ A;  2HXV A;  4ECK A;  2DRC A;  1RA8 A;  3SA1 A;  3TD8 A;  2BLB A;  3GI2 A;  3SRR X;  2DHF A;  4QHV A;  3R33 A;  3JTW A;  3CLB A;  2W3W A;  3QLY A;  4EIL A;  3EX8 A;  1RA3 A;  4LAH X;  3FRB X;  1DAJ A;  4DDR A;  5ECX A;  3FY9 X;  3DAU A;  4Q67 A;  3SH2 A;  3UM5 A;  3EIG A;  1MVT A;  3SRW X;  2P4G A;  4LAG X;  3FRF X;  5DFR A;  2JYB A;  3FYW X;  4LEK X;  3QL3 A;  4KY8 A;  7DFR A;  8DFR A;  3JW3 A;  2FZI A;  3F0B X;  1OHK A;  1KMS A;  1JUV A;  3IRM A;  5HSR A;  1U70 A;  4KAK A;  3QLX A;  1AI9 A;  4ELE A;  5HI6 A;  3SGY A;  3FYV X;  5HQZ A;  3F8Y A;  4QI9 A;  4KLX A;  3ROA A;  5CC9 A;  3EEM A;  1RG7 A;  4HA7 A;  1M7A A;  4X5F A;  3S9U A;  2LF1 A;  3F0V X;  3K47 A;  4EIG A;  3QGT A;  4XT7 A;  3K2H A;  3QYO A;  4XEC X;  4KFJ A;  3SR5 X;  1DYR A;  4KEB A;  3NXT A;  5EAJ A;  5U26 A;  3TQA A;  3NXV A;  4NX6 A;  1LUD A;  4G95 A;  4ELF A;  4QJZ D;  1DG7 A;  2BLC A;  3NXR A;  3Q1H A;  4FGG A;  3SAI A;  1BOZ A;  1S3Y A;  3IRN A;  4I1N A;  5JA3 A;  4Q0D A;  3IA5 A;  4DP3 A;  3INV A;  3DGA A;  5HT4 A;  3E0B A;  3S7A A;  1DIU A;  4IXE D;  1RE7 A;  3NZ6 X;  1LY3 A;  3CL9 A;  1DG5 A;  1DRA A;  4PTJ A;  1DHF A;  1DF7 A;  3OAF A;  1RB3 A;  1S3V A;  5U27 A;  4XE6 X;  2W3V A;  2ANQ A;  3NZ9 X;  3IRO A;  1IA4 A;  3KGY A;  3HJ3 A;  1DR7 A;  2OBC A;  4HOG A;  2W3M A;  1JOM A;  2B3Z A;  1DIS A;  4I13 A;  4CD2 A;  3QLS A;  2GD9 A;  1PDB A;  3GHC A;  1CZ3 A;  3TQ9 A;  2D5N A;  2O7P A;  1VJ3 A;  1QZF A;  1DR1 A;  3F0S X;  4ELH A;  1DLR A;  4FHB A;  3NXY A;  1DYH A;  1DR4 A;  3M09 A;  3SA2 A;  4Q6A A;  4M6L A;  1M79 A;  1RA1 A;  3FRA X;  3NZB X;  1DRH A;  3GHW A;  1U72 A;  3IA4 A;  1HFP A;  2W3B A;  5JG0 X;  1DDS A;  1OHJ A;  4PSY A;  4M6J A;  1AOE A;  1KLK A;  1S3W A;  4XT6 A;  4PSS A;  1DLS A;  1E26 A;  3JVX A;  3FL8 A; 
#chains in the Genus database with same CATH topology
 3FRE X;  2W9S A;  3QG2 A;  1RX7 A;  1RX1 A;  4X5G A;  1DRE A;  4XRB A;  1S3U A;  4M7U A;  4OR7 A;  4IXF X;  3DFR A;  2W9T A;  1RX5 A;  1RX3 A;  3FY8 X;  4LAE X;  3FQV A;  4HA9 A;  4H96 A;  4DPH A;  1BZF A;  3CD2 A;  3KY8 A;  2HM9 A;  3SRU X;  3NRR A;  3DRC A;  2ITH A;  4KL9 A;  4OSG A;  5CCC A;  4X5I A;  2H2Q A;  3DAT A;  1DG8 A;  2HQP A;  4G3M A;  4QLE A;  2ANO A;  1DHI A;  3NXX A;  1CD2 A;  1DHJ A;  3QFX A;  2W9H A;  1DDR A;  3VCO A;  3D80 A;  3KFY A;  1IA1 A;  3SRS X;  4P68 A;  1DR6 A;  5HSU A;  1DYI A;  2W3A A;  5HVB A;  4XT4 A;  2BL9 A;  5HF0 X;  3QLZ A;  4X5J A;  4KJL A;  3JWC A;  3F91 A;  4KY4 A;  3UM6 A;  3F0U X;  3NZC X;  3F8Z A;  3FRD X;  4XT5 A;  2D0K A;  4EJ1 A;  2XW7 A;  4PST A;  1AO8 A;  3UM8 A;  4QJC A;  4DPD A;  4TU5 X;  1RA2 A;  4KJJ A;  6DFR A;  1PD9 A;  1U71 A;  1IA3 A;  3OCH A;  3M08 A;  4KBN A;  4H98 A;  1DRB A;  3NZD A;  3DL5 A;  3TQB A;  1RX6 A;  3S3V A;  2CIG A;  3F0Q X;  1J3I A;  1DR5 A;  3QL0 A;  1RX2 A;  5DXV A;  5HT5 A;  2C2T A;  4KNE A;  4H95 A;  3FQC A;  5ECC A;  4HOF A;  3JWK A;  3ZPC A;  5HPB A;  3QLW A;  3FQ0 A;  4P3Q A;  4GH8 A;  3ZPG A;  4KYA A;  3EEJ A;  3FQF A;  4QLG A;  2CD2 A;  1RC4 A;  1PD8 A;  3K45 A;  2FZJ A;  1DR2 A;  1M78 A;  3JWM A;  3DG8 A;  1ZDR A;  4H97 A;  1MVS A;  4PDJ A;  4X5H A;  4PTH A;  3EEL A;  2BLA A;  1HFR A;  3K74 A;  3LG4 A;  3QYL A;  4M6K A;  1DYJ A;  4RGC A;  4IXG X;  1TDR A;  1RF7 A;  1JOL A;  3FS6 A;  3JSU A;  5HVE A;  3SRQ X;  4P3R A;  3NTZ A;  1DRF A;  2INQ A;  4Q0E A;  3QLR A;  4DFR A;  1HFQ A;  1RA9 A;  2OIP A;  3FQO A;  3GHV A;  4NX7 A;  5E8Q A;  2C2S A;  1RH3 A;  1VDR A;  2AZN A;  4M2X A;  3JWF A;  3NZA X;  3I3R A;  4ELB A;  2W9G A;  1DR3 A;  2G6V A;  1SEJ A;  1YHO A;  3L3R A;  4G8Z X;  3RO9 A;  3SQY X;  5HQY A;  1RD7 A;  4HOE A;  1D1G A;  4M7V A;  2L28 A;  3GYF A;  5FDA A;  5HF2 X;  3NU0 A;  1IA2 A;  4KJK A;  3D84 X;  3I8A X;  4FGH A;  3HBB A;  2KGK A;  3EEK A;  1RX9 A;  3F0X X;  3CSE A;  3DL6 A;  3RG9 A;  4P66 A;  4KM0 A;  4ELG A;  3N0H A;  5HUI A;  3FQZ A;  3TQ8 A;  3FL9 A;  4QLF A;  4XT8 A;  3JW5 A;  1RX4 A;  1RX8 A;  1LY4 A;  3KJR A;  3NXO A;  1KMV A;  2ZZA A;  1J3K A;  3KJS A;  4KM2 A;  1RB2 A;  1J3J A;  3IX9 A;  2QK8 A;  2FZH A;  4KD7 A;  4EIZ A;  2HXV A;  4ECK A;  2DRC A;  1RA8 A;  3SA1 A;  3TD8 A;  2BLB A;  3GI2 A;  3SRR X;  2DHF A;  4QHV A;  3R33 A;  3JTW A;  3CLB A;  2W3W A;  3QLY A;  4EIL A;  3EX8 A;  1RA3 A;  4LAH X;  3FRB X;  1DAJ A;  4DDR A;  5ECX A;  3FY9 X;  3DAU A;  4Q67 A;  3SH2 A;  3UM5 A;  3EIG A;  1MVT A;  3SRW X;  2P4G A;  4LAG X;  3FRF X;  5DFR A;  2JYB A;  3FYW X;  4LEK X;  3QL3 A;  4KY8 A;  7DFR A;  8DFR A;  3JW3 A;  2FZI A;  3F0B X;  1OHK A;  1KMS A;  1JUV A;  3IRM A;  5HSR A;  1U70 A;  4KAK A;  3QLX A;  1AI9 A;  4ELE A;  5HI6 A;  3SGY A;  3FYV X;  5HQZ A;  3F8Y A;  4QI9 A;  4KLX A;  3ROA A;  5CC9 A;  3EEM A;  1RG7 A;  4HA7 A;  1M7A A;  4X5F A;  3S9U A;  2LF1 A;  3F0V X;  3K47 A;  4EIG A;  3QGT A;  4XT7 A;  3K2H A;  3QYO A;  4XEC X;  4KFJ A;  3SR5 X;  1DYR A;  4KEB A;  3NXT A;  5EAJ A;  5U26 A;  3TQA A;  3NXV A;  4NX6 A;  1LUD A;  4G95 A;  4ELF A;  4QJZ D;  1DG7 A;  2BLC A;  3NXR A;  3Q1H A;  4FGG A;  3SAI A;  1BOZ A;  1S3Y A;  3IRN A;  4I1N A;  5JA3 A;  4Q0D A;  3IA5 A;  4DP3 A;  3INV A;  3DGA A;  5HT4 A;  3E0B A;  3S7A A;  1DIU A;  4IXE D;  1RE7 A;  3NZ6 X;  1LY3 A;  3CL9 A;  1DG5 A;  1DRA A;  4PTJ A;  1DHF A;  1DF7 A;  3OAF A;  1RB3 A;  1S3V A;  5U27 A;  4XE6 X;  2W3V A;  2ANQ A;  3NZ9 X;  3IRO A;  1IA4 A;  3KGY A;  3HJ3 A;  1DR7 A;  2OBC A;  4HOG A;  2W3M A;  1JOM A;  2B3Z A;  1DIS A;  4I13 A;  4CD2 A;  3QLS A;  2GD9 A;  1PDB A;  3GHC A;  1CZ3 A;  3TQ9 A;  2D5N A;  2O7P A;  1VJ3 A;  1QZF A;  1DR1 A;  3F0S X;  4ELH A;  1DLR A;  4FHB A;  3NXY A;  1DYH A;  1DR4 A;  3M09 A;  3SA2 A;  4Q6A A;  4M6L A;  1M79 A;  1RA1 A;  3FRA X;  3NZB X;  1DRH A;  3GHW A;  1U72 A;  3IA4 A;  1HFP A;  2W3B A;  5JG0 X;  1DDS A;  1OHJ A;  4PSY A;  4M6J A;  1AOE A;  1KLK A;  1S3W A;  4XT6 A;  4PSS A;  1DLS A;  1E26 A;  3JVX A;  3FL8 A; 
#chains in the Genus database with same CATH homology
 3FRE X;  2W9S A;  3QG2 A;  1RX7 A;  1RX1 A;  4X5G A;  1DRE A;  4XRB A;  1S3U A;  4M7U A;  4OR7 A;  4IXF X;  3DFR A;  2W9T A;  1RX5 A;  1RX3 A;  3FY8 X;  4LAE X;  3FQV A;  4HA9 A;  4H96 A;  4DPH A;  1BZF A;  3CD2 A;  3KY8 A;  2HM9 A;  3SRU X;  3NRR A;  3DRC A;  2ITH A;  4KL9 A;  4OSG A;  5CCC A;  4X5I A;  2H2Q A;  3DAT A;  1DG8 A;  2HQP A;  4G3M A;  4QLE A;  2ANO A;  1DHI A;  3NXX A;  1CD2 A;  1DHJ A;  3QFX A;  2W9H A;  1DDR A;  3VCO A;  3D80 A;  3KFY A;  1IA1 A;  3SRS X;  4P68 A;  1DR6 A;  5HSU A;  1DYI A;  2W3A A;  5HVB A;  4XT4 A;  2BL9 A;  5HF0 X;  3QLZ A;  4X5J A;  4KJL A;  3JWC A;  3F91 A;  4KY4 A;  3UM6 A;  3F0U X;  3NZC X;  3F8Z A;  3FRD X;  4XT5 A;  2D0K A;  4EJ1 A;  2XW7 A;  4PST A;  1AO8 A;  3UM8 A;  4QJC A;  4DPD A;  4TU5 X;  1RA2 A;  4KJJ A;  6DFR A;  1PD9 A;  1U71 A;  1IA3 A;  3OCH A;  3M08 A;  4KBN A;  4H98 A;  1DRB A;  3NZD A;  3DL5 A;  3TQB A;  1RX6 A;  3S3V A;  2CIG A;  3F0Q X;  1J3I A;  1DR5 A;  3QL0 A;  1RX2 A;  5DXV A;  5HT5 A;  2C2T A;  4KNE A;  4H95 A;  3FQC A;  5ECC A;  4HOF A;  3JWK A;  3ZPC A;  5HPB A;  3QLW A;  3FQ0 A;  4P3Q A;  4GH8 A;  3ZPG A;  4KYA A;  3EEJ A;  3FQF A;  4QLG A;  2CD2 A;  1RC4 A;  1PD8 A;  3K45 A;  2FZJ A;  1DR2 A;  1M78 A;  3JWM A;  3DG8 A;  1ZDR A;  4H97 A;  1MVS A;  4PDJ A;  4X5H A;  4PTH A;  3EEL A;  2BLA A;  1HFR A;  3K74 A;  3LG4 A;  3QYL A;  4M6K A;  1DYJ A;  4RGC A;  4IXG X;  1TDR A;  1RF7 A;  1JOL A;  3FS6 A;  3JSU A;  5HVE A;  3SRQ X;  4P3R A;  3NTZ A;  1DRF A;  2INQ A;  4Q0E A;  3QLR A;  4DFR A;  1HFQ A;  1RA9 A;  2OIP A;  3FQO A;  3GHV A;  4NX7 A;  5E8Q A;  2C2S A;  1RH3 A;  1VDR A;  2AZN A;  4M2X A;  3JWF A;  3NZA X;  3I3R A;  4ELB A;  2W9G A;  1DR3 A;  2G6V A;  1SEJ A;  1YHO A;  3L3R A;  4G8Z X;  3RO9 A;  3SQY X;  5HQY A;  1RD7 A;  4HOE A;  1D1G A;  4M7V A;  2L28 A;  3GYF A;  5FDA A;  5HF2 X;  3NU0 A;  1IA2 A;  4KJK A;  3D84 X;  3I8A X;  4FGH A;  3HBB A;  2KGK A;  3EEK A;  1RX9 A;  3F0X X;  3CSE A;  3DL6 A;  3RG9 A;  4P66 A;  4KM0 A;  4ELG A;  3N0H A;  5HUI A;  3FQZ A;  3TQ8 A;  3FL9 A;  4QLF A;  4XT8 A;  3JW5 A;  1RX4 A;  1RX8 A;  1LY4 A;  3KJR A;  3NXO A;  1KMV A;  2ZZA A;  1J3K A;  3KJS A;  4KM2 A;  1RB2 A;  1J3J A;  3IX9 A;  2QK8 A;  2FZH A;  4KD7 A;  4EIZ A;  2HXV A;  4ECK A;  2DRC A;  1RA8 A;  3SA1 A;  3TD8 A;  2BLB A;  3GI2 A;  3SRR X;  2DHF A;  4QHV A;  3R33 A;  3JTW A;  3CLB A;  2W3W A;  3QLY A;  4EIL A;  3EX8 A;  1RA3 A;  4LAH X;  3FRB X;  1DAJ A;  4DDR A;  5ECX A;  3FY9 X;  3DAU A;  4Q67 A;  3SH2 A;  3UM5 A;  3EIG A;  1MVT A;  3SRW X;  2P4G A;  4LAG X;  3FRF X;  5DFR A;  2JYB A;  3FYW X;  4LEK X;  3QL3 A;  4KY8 A;  7DFR A;  8DFR A;  3JW3 A;  2FZI A;  3F0B X;  1OHK A;  1KMS A;  1JUV A;  3IRM A;  5HSR A;  1U70 A;  4KAK A;  3QLX A;  1AI9 A;  4ELE A;  5HI6 A;  3SGY A;  3FYV X;  5HQZ A;  3F8Y A;  4QI9 A;  4KLX A;  3ROA A;  5CC9 A;  3EEM A;  1RG7 A;  4HA7 A;  1M7A A;  4X5F A;  3S9U A;  2LF1 A;  3F0V X;  3K47 A;  4EIG A;  3QGT A;  4XT7 A;  3K2H A;  3QYO A;  4XEC X;  4KFJ A;  3SR5 X;  1DYR A;  4KEB A;  3NXT A;  5EAJ A;  5U26 A;  3TQA A;  3NXV A;  4NX6 A;  1LUD A;  4G95 A;  4ELF A;  4QJZ D;  1DG7 A;  2BLC A;  3NXR A;  3Q1H A;  4FGG A;  3SAI A;  1BOZ A;  1S3Y A;  3IRN A;  4I1N A;  5JA3 A;  4Q0D A;  3IA5 A;  4DP3 A;  3INV A;  3DGA A;  5HT4 A;  3E0B A;  3S7A A;  1DIU A;  4IXE D;  1RE7 A;  3NZ6 X;  1LY3 A;  3CL9 A;  1DG5 A;  1DRA A;  4PTJ A;  1DHF A;  1DF7 A;  3OAF A;  1RB3 A;  1S3V A;  5U27 A;  4XE6 X;  2W3V A;  2ANQ A;  3NZ9 X;  3IRO A;  1IA4 A;  3KGY A;  3HJ3 A;  1DR7 A;  2OBC A;  4HOG A;  2W3M A;  1JOM A;  2B3Z A;  1DIS A;  4I13 A;  4CD2 A;  3QLS A;  2GD9 A;  1PDB A;  3GHC A;  1CZ3 A;  3TQ9 A;  2D5N A;  2O7P A;  1VJ3 A;  1QZF A;  1DR1 A;  3F0S X;  4ELH A;  1DLR A;  4FHB A;  3NXY A;  1DYH A;  1DR4 A;  3M09 A;  3SA2 A;  4Q6A A;  4M6L A;  1M79 A;  1RA1 A;  3FRA X;  3NZB X;  1DRH A;  3GHW A;  1U72 A;  3IA4 A;  1HFP A;  2W3B A;  5JG0 X;  1DDS A;  1OHJ A;  4PSY A;  4M6J A;  1AOE A;  1KLK A;  1S3W A;  4XT6 A;  4PSS A;  1DLS A;  1E26 A;  3JVX A;  3FL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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