1RX6A

Dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate and nicotinamide adenine dinucleotide phosphate (reduced form)
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 48
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rx6A00
3DL5A 1MVSA 2W9GA 5HF0X 4CD2A 5HVEA 4Q0EA 3L3RA 3NZ9X 3EX8A 2FZJA 5ECCA 3JTWA 1AI9A 3EELA 1RX4A 4P3RA 4XT4A 4H95A 1E26A 4I1NA 1IA1A 3FRFX 4XE6X 4M7VA 1DR7A 3M08A 1HFPA 1RX3A 3ZPGA 4M6KA 5U26A 1CZ3A 4KEBA 3SRQX 3CD2A 3K45A 3S9UA 2W9HA 4LAEX 4H98A 1RA8A 2ANOA 4QLFA 3FQZA 5HVBA 1RX7A 2DHFA 3KGYA 3CSEA 1OHKA 4KAKA 4EJ1A 4H96A 1D1GA 2W3VA 3QLXA 5JA3A 4FGHA 4ELHA 3F0SX 5ECXA 1BOZA 3SRRX 3I3RA 4Q6AA 1U70A 1DRFA 1PDBA 3UM6A 1RH3A 1RX1A 2XW7A 3KJRA 3HJ3A 1DR6A 4M6LA 2JYBA 2W3MA 3S3VA 3NXXA 1DR5A 2CIGA 4OSGA 3KY8A 4RGCA 4KL9A 3TQBA 1IA3A 3NXYA 4KJJA 4P3QA 2C2TA 3OAFA 4PSTA 3JWCA 4KD7A 1RX6A 4KNEA 1U72A 4PSYA 4XRBA 3NU0A 3IROA 3GI2A 4X5JA 4OR7A 1DYJA 1S3WA 4P68A 1DREA 2OBCA 1RA9A 3EIGA 4DDRA 3R33A 1RC4A 1HFQA 1ZDRA 3RO9A 1RX9A 1M7AA 4QLEA 1J3JA 2KGKA 2W3WA 1AOEA 1DRAA 3GHCA 1DG5A 2BL9A 5JG0X 3DATA 1J3KA 5HQYA 3FL8A 3FS6A 2W9SA 8DFRA 3KJSA 4QI9A 2FZIA 1LY3A 2FZHA 2D0KA 3FYVX 3FYWX 2ANQA 1JOLA 6DFRA 1J3IA 3QLWA 4ELEA 1DDSA 3JVXA 3KFYA 1RB2A 3JWMA 1LY4A 5HUIA 4XECX 3FQFA 4DPHA 4FGGA 1DHIA 3QL3A 3OCHA 4NX6A 3NZAX 3TD8A 2INQA 1LUDA 1RE7A 3SA2A 3EEJA 3EEKA 2BLAA 1SEJA 1JUVA 3TQAA 2P4GA 4G95A 1DR2A 1KLKA 3VCOA 4DP3A 4XT6A 3NXVA 2AZNA 2OIPA 3FREX 3F0VX 2L28A 3IRMA 2CD2A 4HA7A 5CC9A 4KY8A 3JWKA 1DR1A 2HM9A 4XT5A 3NZDA 3D80A 1JOMA 2B3ZA 3UM8A 2D5NA 5HQZA 3SQYX 4X5FA 1DYHA 3NZCX 3SRWX 1DRHA 5HSRA 5FDAA 3F0XX 3N0HA 3SAIA 3NXRA 1RA3A 3FQCA 3JWFA 1DR3A 3QLZA 3JSUA 3FY9X 1QZFA 3EEMA 4LAHX 3JW3A 1DHFA 3NXTA 3QLSA 4X5GA 3NRRA 4PSSA 2GD9A 1RA1A 5EAJA 1DF7A 4G8ZX 1RX8A 3E0BA 4NX7A 4X5IA 3RG9A 5HPBA 1BZFA 3IA4A 2QK8A 3QLYA 3IX9A 4ELBA 2W9TA 5DXVA 3K2HA 1KMSA 3FL9A 3F0UX 7DFRA 3ROAA 3FRBX 1PD8A 1S3YA 2HXVA 4DPDA 3CL9A 2G6VA 3SH2A 3QYLA 3HBBA 1M78A 3SR5X 5U27A 2LF1A 3IRNA 3GYFA 2W3AA 2ITHA 1YHOA 1IA4A 3FQ0A 5E8QA 2C2SA 4KM2A 1AO8A 1DRBA 1MVTA 3NXOA 3TQ8A 3DG8A 4HOFA 1HFRA 5DFRA 3CLBA 5CCCA 3INVA 1RA2A 1DDRA 1DAJA 4KM0A 1IA2A 4ECKA 4XT7A 4IXFX 3SA1A 3NTZA 1S3UA 4TU5X 2HQPA 3F8ZA 1KMVA 1DISA 1DYIA 4FHBA 4M6JA 1M79A 5HSUA 4KJLA 3LG4A 4QJZD 2DRCA 4EILA 1VDRA 2H2QA 1DIUA 2O7PA 5HF2X 4PTHA 3Q1HA 1U71A 4ELGA 3F91A 4EIGA 4KJKA 3K47A 4DFRA 5HT5A 3I8AX 3JW5A 3FRAX 4GH8A 3DRCA 2BLCA 4QJCA 3F0BX 4PDJA 1PD9A 3NZ6X 3QYOA 3QFXA 4KBNA 3QG2A 3D84X 3QLRA 1DLSA 4HOEA 2BLBA 4IXGX 4QHVA 3FQVA 4Q67A 1RG7A 5HT4A 3GHWA 3DFRA 1RF7A 4HOGA 1S3VA 1DHJA 4M7UA 4KFJA 1RX2A 3NZBX 1RD7A 1CD2A 3SGYA 1DG7A 1DYRA 3K74A 4ELFA 1DLRA 3QGTA 1OHJA 1DR4A 4KY4A 1VJ3A 2W3BA 4X5HA 3FRDX 4P66A 3GHVA 3F8YA 1DG8A 3DGAA 3DL6A 4I13A 4XT8A 4HA9A 4QLGA 4KLXA 4G3MA 3TQ9A 3SRUX 3QL0A 4KYAA 3F0QX 3UM5A 3IA5A 4LAGX 4EIZA 4IXED 5HI6A 3FY8X 4LEKX 1RX5A 3M09A 1RB3A 4M2XA 3S7AA 3SRSX 4PTJA 1TDRA 2ZZAA 3DAUA 4H97A 3ZPCA 3FQOA 4Q0DA
chains in the Genus database with same CATH superfamily
3DL5A 1MVSA 2W9GA 5HF0X 4CD2A 5HVEA 4Q0EA 3L3RA 3NZ9X 3EX8A 2FZJA 5ECCA 3JTWA 1AI9A 3EELA 1RX4A 4P3RA 4XT4A 4H95A 1E26A 4I1NA 1IA1A 3FRFX 4XE6X 4M7VA 1DR7A 3M08A 1HFPA 1RX3A 3ZPGA 4M6KA 5U26A 1CZ3A 4KEBA 3SRQX 3CD2A 3K45A 3S9UA 2W9HA 4LAEX 4H98A 1RA8A 2ANOA 4QLFA 3FQZA 5HVBA 1RX7A 2DHFA 3KGYA 3CSEA 1OHKA 4KAKA 4EJ1A 4H96A 1D1GA 2W3VA 3QLXA 5JA3A 4FGHA 4ELHA 3F0SX 5ECXA 1BOZA 3SRRX 3I3RA 4Q6AA 1U70A 1DRFA 1PDBA 3UM6A 1RH3A 1RX1A 2XW7A 3KJRA 3HJ3A 1DR6A 4M6LA 2JYBA 2W3MA 3S3VA 3NXXA 1DR5A 2CIGA 4OSGA 3KY8A 4RGCA 4KL9A 3TQBA 1IA3A 3NXYA 4KJJA 4P3QA 2C2TA 3OAFA 4PSTA 3JWCA 4KD7A 1RX6A 4KNEA 1U72A 4PSYA 4XRBA 3NU0A 3IROA 3GI2A 4X5JA 4OR7A 1DYJA 1S3WA 4P68A 1DREA 2OBCA 1RA9A 3EIGA 4DDRA 3R33A 1RC4A 1HFQA 1ZDRA 3RO9A 1RX9A 1M7AA 4QLEA 1J3JA 2KGKA 2W3WA 1AOEA 1DRAA 3GHCA 1DG5A 2BL9A 5JG0X 3DATA 1J3KA 5HQYA 3FL8A 3FS6A 2W9SA 8DFRA 3KJSA 4QI9A 2FZIA 1LY3A 2FZHA 2D0KA 3FYVX 3FYWX 2ANQA 1JOLA 6DFRA 1J3IA 3QLWA 4ELEA 1DDSA 3JVXA 3KFYA 1RB2A 3JWMA 1LY4A 5HUIA 4XECX 3FQFA 4DPHA 4FGGA 1DHIA 3QL3A 3OCHA 4NX6A 3NZAX 3TD8A 2INQA 1LUDA 1RE7A 3SA2A 3EEJA 3EEKA 2BLAA 1SEJA 1JUVA 3TQAA 2P4GA 4G95A 1DR2A 1KLKA 3VCOA 4DP3A 4XT6A 3NXVA 2AZNA 2OIPA 3FREX 3F0VX 2L28A 3IRMA 2CD2A 4HA7A 5CC9A 4KY8A 3JWKA 1DR1A 2HM9A 4XT5A 3NZDA 3D80A 1JOMA 2B3ZA 3UM8A 2D5NA 5HQZA 3SQYX 4X5FA 1DYHA 3NZCX 3SRWX 1DRHA 5HSRA 5FDAA 3F0XX 3N0HA 3SAIA 3NXRA 1RA3A 3FQCA 3JWFA 1DR3A 3QLZA 3JSUA 3FY9X 1QZFA 3EEMA 4LAHX 3JW3A 1DHFA 3NXTA 3QLSA 4X5GA 3NRRA 4PSSA 2GD9A 1RA1A 5EAJA 1DF7A 4G8ZX 1RX8A 3E0BA 4NX7A 4X5IA 3RG9A 5HPBA 1BZFA 3IA4A 2QK8A 3QLYA 3IX9A 4ELBA 2W9TA 5DXVA 3K2HA 1KMSA 3FL9A 3F0UX 7DFRA 3ROAA 3FRBX 1PD8A 1S3YA 2HXVA 4DPDA 3CL9A 2G6VA 3SH2A 3QYLA 3HBBA 1M78A 3SR5X 5U27A 2LF1A 3IRNA 3GYFA 2W3AA 2ITHA 1YHOA 1IA4A 3FQ0A 5E8QA 2C2SA 4KM2A 1AO8A 1DRBA 1MVTA 3NXOA 3TQ8A 3DG8A 4HOFA 1HFRA 5DFRA 3CLBA 5CCCA 3INVA 1RA2A 1DDRA 1DAJA 4KM0A 1IA2A 4ECKA 4XT7A 4IXFX 3SA1A 3NTZA 1S3UA 4TU5X 2HQPA 3F8ZA 1KMVA 1DISA 1DYIA 4FHBA 4M6JA 1M79A 5HSUA 4KJLA 3LG4A 4QJZD 2DRCA 4EILA 1VDRA 2H2QA 1DIUA 2O7PA 5HF2X 4PTHA 3Q1HA 1U71A 4ELGA 3F91A 4EIGA 4KJKA 3K47A 4DFRA 5HT5A 3I8AX 3JW5A 3FRAX 4GH8A 3DRCA 2BLCA 4QJCA 3F0BX 4PDJA 1PD9A 3NZ6X 3QYOA 3QFXA 4KBNA 3QG2A 3D84X 3QLRA 1DLSA 4HOEA 2BLBA 4IXGX 4QHVA 3FQVA 4Q67A 1RG7A 5HT4A 3GHWA 3DFRA 1RF7A 4HOGA 1S3VA 1DHJA 4M7UA 4KFJA 1RX2A 3NZBX 1RD7A 1CD2A 3SGYA 1DG7A 1DYRA 3K74A 4ELFA 1DLRA 3QGTA 1OHJA 1DR4A 4KY4A 1VJ3A 2W3BA 4X5HA 3FRDX 4P66A 3GHVA 3F8YA 1DG8A 3DGAA 3DL6A 4I13A 4XT8A 4HA9A 4QLGA 4KLXA 4G3MA 3TQ9A 3SRUX 3QL0A 4KYAA 3F0QX 3UM5A 3IA5A 4LAGX 4EIZA 4IXED 5HI6A 3FY8X 4LEKX 1RX5A 3M09A 1RB3A 4M2XA 3S7AA 3SRSX 4PTJA 1TDRA 2ZZAA 3DAUA 4H97A 3ZPCA 3FQOA 4Q0DA
chains in the Genus database with same CATH topology
3DL5A 1MVSA 2W9GA 5HF0X 4CD2A 5HVEA 4Q0EA 3L3RA 3NZ9X 3EX8A 2FZJA 5ECCA 3JTWA 1AI9A 3EELA 1RX4A 4P3RA 4XT4A 4H95A 1E26A 4I1NA 1IA1A 3FRFX 4XE6X 4M7VA 1DR7A 3M08A 1HFPA 1RX3A 3ZPGA 4M6KA 5U26A 1CZ3A 4KEBA 3SRQX 3CD2A 3K45A 3S9UA 2W9HA 4LAEX 4H98A 1RA8A 2ANOA 4QLFA 3FQZA 5HVBA 1RX7A 2DHFA 3KGYA 3CSEA 1OHKA 4KAKA 4EJ1A 4H96A 1D1GA 2W3VA 3QLXA 5JA3A 4FGHA 4ELHA 3F0SX 5ECXA 1BOZA 3SRRX 3I3RA 4Q6AA 1U70A 1DRFA 1PDBA 3UM6A 1RH3A 1RX1A 2XW7A 3KJRA 3HJ3A 1DR6A 4M6LA 2JYBA 2W3MA 3S3VA 3NXXA 1DR5A 2CIGA 4OSGA 3KY8A 4RGCA 4KL9A 3TQBA 1IA3A 3NXYA 4KJJA 4P3QA 2C2TA 3OAFA 4PSTA 3JWCA 4KD7A 1RX6A 4KNEA 1U72A 4PSYA 4XRBA 3NU0A 3IROA 3GI2A 4X5JA 4OR7A 1DYJA 1S3WA 4P68A 1DREA 2OBCA 1RA9A 3EIGA 4DDRA 3R33A 1RC4A 1HFQA 1ZDRA 3RO9A 1RX9A 1M7AA 4QLEA 1J3JA 2KGKA 2W3WA 1AOEA 1DRAA 3GHCA 1DG5A 2BL9A 5JG0X 3DATA 1J3KA 5HQYA 3FL8A 3FS6A 2W9SA 8DFRA 3KJSA 4QI9A 2FZIA 1LY3A 2FZHA 2D0KA 3FYVX 3FYWX 2ANQA 1JOLA 6DFRA 1J3IA 3QLWA 4ELEA 1DDSA 3JVXA 3KFYA 1RB2A 3JWMA 1LY4A 5HUIA 4XECX 3FQFA 4DPHA 4FGGA 1DHIA 3QL3A 3OCHA 4NX6A 3NZAX 3TD8A 2INQA 1LUDA 1RE7A 3SA2A 3EEJA 3EEKA 2BLAA 1SEJA 1JUVA 3TQAA 2P4GA 4G95A 1DR2A 1KLKA 3VCOA 4DP3A 4XT6A 3NXVA 2AZNA 2OIPA 3FREX 3F0VX 2L28A 3IRMA 2CD2A 4HA7A 5CC9A 4KY8A 3JWKA 1DR1A 2HM9A 4XT5A 3NZDA 3D80A 1JOMA 2B3ZA 3UM8A 2D5NA 5HQZA 3SQYX 4X5FA 1DYHA 3NZCX 3SRWX 1DRHA 5HSRA 5FDAA 3F0XX 3N0HA 3SAIA 3NXRA 1RA3A 3FQCA 3JWFA 1DR3A 3QLZA 3JSUA 3FY9X 1QZFA 3EEMA 4LAHX 3JW3A 1DHFA 3NXTA 3QLSA 4X5GA 3NRRA 4PSSA 2GD9A 1RA1A 5EAJA 1DF7A 4G8ZX 1RX8A 3E0BA 4NX7A 4X5IA 3RG9A 5HPBA 1BZFA 3IA4A 2QK8A 3QLYA 3IX9A 4ELBA 2W9TA 5DXVA 3K2HA 1KMSA 3FL9A 3F0UX 7DFRA 3ROAA 3FRBX 1PD8A 1S3YA 2HXVA 4DPDA 3CL9A 2G6VA 3SH2A 3QYLA 3HBBA 1M78A 3SR5X 5U27A 2LF1A 3IRNA 3GYFA 2W3AA 2ITHA 1YHOA 1IA4A 3FQ0A 5E8QA 2C2SA 4KM2A 1AO8A 1DRBA 1MVTA 3NXOA 3TQ8A 3DG8A 4HOFA 1HFRA 5DFRA 3CLBA 5CCCA 3INVA 1RA2A 1DDRA 1DAJA 4KM0A 1IA2A 4ECKA 4XT7A 4IXFX 3SA1A 3NTZA 1S3UA 4TU5X 2HQPA 3F8ZA 1KMVA 1DISA 1DYIA 4FHBA 4M6JA 1M79A 5HSUA 4KJLA 3LG4A 4QJZD 2DRCA 4EILA 1VDRA 2H2QA 1DIUA 2O7PA 5HF2X 4PTHA 3Q1HA 1U71A 4ELGA 3F91A 4EIGA 4KJKA 3K47A 4DFRA 5HT5A 3I8AX 3JW5A 3FRAX 4GH8A 3DRCA 2BLCA 4QJCA 3F0BX 4PDJA 1PD9A 3NZ6X 3QYOA 3QFXA 4KBNA 3QG2A 3D84X 3QLRA 1DLSA 4HOEA 2BLBA 4IXGX 4QHVA 3FQVA 4Q67A 1RG7A 5HT4A 3GHWA 3DFRA 1RF7A 4HOGA 1S3VA 1DHJA 4M7UA 4KFJA 1RX2A 3NZBX 1RD7A 1CD2A 3SGYA 1DG7A 1DYRA 3K74A 4ELFA 1DLRA 3QGTA 1OHJA 1DR4A 4KY4A 1VJ3A 2W3BA 4X5HA 3FRDX 4P66A 3GHVA 3F8YA 1DG8A 3DGAA 3DL6A 4I13A 4XT8A 4HA9A 4QLGA 4KLXA 4G3MA 3TQ9A 3SRUX 3QL0A 4KYAA 3F0QX 3UM5A 3IA5A 4LAGX 4EIZA 4IXED 5HI6A 3FY8X 4LEKX 1RX5A 3M09A 1RB3A 4M2XA 3S7AA 3SRSX 4PTJA 1TDRA 2ZZAA 3DAUA 4H97A 3ZPCA 3FQOA 4Q0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DL5 A;  1MVS A;  2W9G A;  5HF0 X;  4CD2 A;  5HVE A;  4Q0E A;  3L3R A;  3NZ9 X;  3EX8 A;  2FZJ A;  5ECC A;  3JTW A;  1AI9 A;  3EEL A;  1RX4 A;  4P3R A;  4XT4 A;  4H95 A;  1E26 A;  4I1N A;  1IA1 A;  3FRF X;  4XE6 X;  4M7V A;  1DR7 A;  3M08 A;  1HFP A;  1RX3 A;  3ZPG A;  4M6K A;  5U26 A;  1CZ3 A;  4KEB A;  3SRQ X;  3CD2 A;  3K45 A;  3S9U A;  2W9H A;  4LAE X;  4H98 A;  1RA8 A;  2ANO A;  4QLF A;  3FQZ A;  5HVB A;  1RX7 A;  2DHF A;  3KGY A;  3CSE A;  1OHK A;  4KAK A;  4EJ1 A;  4H96 A;  1D1G A;  2W3V A;  3QLX A;  5JA3 A;  4FGH A;  4ELH A;  3F0S X;  5ECX A;  1BOZ A;  3SRR X;  3I3R A;  4Q6A A;  1U70 A;  1DRF A;  1PDB A;  3UM6 A;  1RH3 A;  1RX1 A;  2XW7 A;  3KJR A;  3HJ3 A;  1DR6 A;  4M6L A;  2JYB A;  2W3M A;  3S3V A;  3NXX A;  1DR5 A;  2CIG A;  4OSG A;  3KY8 A;  4RGC A;  4KL9 A;  3TQB A;  1IA3 A;  3NXY A;  4KJJ A;  4P3Q A;  2C2T A;  3OAF A;  4PST A;  3JWC A;  4KD7 A;  1RX6 A;  4KNE A;  1U72 A;  4PSY A;  4XRB A;  3NU0 A;  3IRO A;  3GI2 A;  4X5J A;  4OR7 A;  1DYJ A;  1S3W A;  4P68 A;  1DRE A;  2OBC A;  1RA9 A;  3EIG A;  4DDR A;  3R33 A;  1RC4 A;  1HFQ A;  1ZDR A;  3RO9 A;  1RX9 A;  1M7A A;  4QLE A;  1J3J A;  2KGK A;  2W3W A;  1AOE A;  1DRA A;  3GHC A;  1DG5 A;  2BL9 A;  5JG0 X;  3DAT A;  1J3K A;  5HQY A;  3FL8 A;  3FS6 A;  2W9S A;  8DFR A;  3KJS A;  4QI9 A;  2FZI A;  1LY3 A;  2FZH A;  2D0K A;  3FYV X;  3FYW X;  2ANQ A;  1JOL A;  6DFR A;  1J3I A;  3QLW A;  4ELE A;  1DDS A;  3JVX A;  3KFY A;  1RB2 A;  3JWM A;  1LY4 A;  5HUI A;  4XEC X;  3FQF A;  4DPH A;  4FGG A;  1DHI A;  3QL3 A;  3OCH A;  4NX6 A;  3NZA X;  3TD8 A;  2INQ A;  1LUD A;  1RE7 A;  3SA2 A;  3EEJ A;  3EEK A;  2BLA A;  1SEJ A;  1JUV A;  3TQA A;  2P4G A;  4G95 A;  1DR2 A;  1KLK A;  3VCO A;  4DP3 A;  4XT6 A;  3NXV A;  2AZN A;  2OIP A;  3FRE X;  3F0V X;  2L28 A;  3IRM A;  2CD2 A;  4HA7 A;  5CC9 A;  4KY8 A;  3JWK A;  1DR1 A;  2HM9 A;  4XT5 A;  3NZD A;  3D80 A;  1JOM A;  2B3Z A;  3UM8 A;  2D5N A;  5HQZ A;  3SQY X;  4X5F A;  1DYH A;  3NZC X;  3SRW X;  1DRH A;  5HSR A;  5FDA A;  3F0X X;  3N0H A;  3SAI A;  3NXR A;  1RA3 A;  3FQC A;  3JWF A;  1DR3 A;  3QLZ A;  3JSU A;  3FY9 X;  1QZF A;  3EEM A;  4LAH X;  3JW3 A;  1DHF A;  3NXT A;  3QLS A;  4X5G A;  3NRR A;  4PSS A;  2GD9 A;  1RA1 A;  5EAJ A;  1DF7 A;  4G8Z X;  1RX8 A;  3E0B A;  4NX7 A;  4X5I A;  3RG9 A;  5HPB A;  1BZF A;  3IA4 A;  2QK8 A;  3QLY A;  3IX9 A;  4ELB A;  2W9T A;  5DXV A;  3K2H A;  1KMS A;  3FL9 A;  3F0U X;  7DFR A;  3ROA A;  3FRB X;  1PD8 A;  1S3Y A;  2HXV A;  4DPD A;  3CL9 A;  2G6V A;  3SH2 A;  3QYL A;  3HBB A;  1M78 A;  3SR5 X;  5U27 A;  2LF1 A;  3IRN A;  3GYF A;  2W3A A;  2ITH A;  1YHO A;  1IA4 A;  3FQ0 A;  5E8Q A;  2C2S A;  4KM2 A;  1AO8 A;  1DRB A;  1MVT A;  3NXO A;  3TQ8 A;  3DG8 A;  4HOF A;  1HFR A;  5DFR A;  3CLB A;  5CCC A;  3INV A;  1RA2 A;  1DDR A;  1DAJ A;  4KM0 A;  1IA2 A;  4ECK A;  4XT7 A;  4IXF X;  3SA1 A;  3NTZ A;  1S3U A;  4TU5 X;  2HQP A;  3F8Z A;  1KMV A;  1DIS A;  1DYI A;  4FHB A;  4M6J A;  1M79 A;  5HSU A;  4KJL A;  3LG4 A;  4QJZ D;  2DRC A;  4EIL A;  1VDR A;  2H2Q A;  1DIU A;  2O7P A;  5HF2 X;  4PTH A;  3Q1H A;  1U71 A;  4ELG A;  3F91 A;  4EIG A;  4KJK A;  3K47 A;  4DFR A;  5HT5 A;  3I8A X;  3JW5 A;  3FRA X;  4GH8 A;  3DRC A;  2BLC A;  4QJC A;  3F0B X;  4PDJ A;  1PD9 A;  3NZ6 X;  3QYO A;  3QFX A;  4KBN A;  3QG2 A;  3D84 X;  3QLR A;  1DLS A;  4HOE A;  2BLB A;  4IXG X;  4QHV A;  3FQV A;  4Q67 A;  1RG7 A;  5HT4 A;  3GHW A;  3DFR A;  1RF7 A;  4HOG A;  1S3V A;  1DHJ A;  4M7U A;  4KFJ A;  1RX2 A;  3NZB X;  1RD7 A;  1CD2 A;  3SGY A;  1DG7 A;  1DYR A;  3K74 A;  4ELF A;  1DLR A;  3QGT A;  1OHJ A;  1DR4 A;  4KY4 A;  1VJ3 A;  2W3B A;  4X5H A;  3FRD X;  4P66 A;  3GHV A;  3F8Y A;  1DG8 A;  3DGA A;  3DL6 A;  4I13 A;  4XT8 A;  4HA9 A;  4QLG A;  4KLX A;  4G3M A;  3TQ9 A;  3SRU X;  3QL0 A;  4KYA A;  3F0Q X;  3UM5 A;  3IA5 A;  4LAG X;  4EIZ A;  4IXE D;  5HI6 A;  3FY8 X;  4LEK X;  1RX5 A;  3M09 A;  1RB3 A;  4M2X A;  3S7A A;  3SRS X;  4PTJ A;  1TDR A;  2ZZA A;  3DAU A;  4H97 A;  3ZPC A;  3FQO A;  4Q0D A; 
#chains in the Genus database with same CATH topology
 3DL5 A;  1MVS A;  2W9G A;  5HF0 X;  4CD2 A;  5HVE A;  4Q0E A;  3L3R A;  3NZ9 X;  3EX8 A;  2FZJ A;  5ECC A;  3JTW A;  1AI9 A;  3EEL A;  1RX4 A;  4P3R A;  4XT4 A;  4H95 A;  1E26 A;  4I1N A;  1IA1 A;  3FRF X;  4XE6 X;  4M7V A;  1DR7 A;  3M08 A;  1HFP A;  1RX3 A;  3ZPG A;  4M6K A;  5U26 A;  1CZ3 A;  4KEB A;  3SRQ X;  3CD2 A;  3K45 A;  3S9U A;  2W9H A;  4LAE X;  4H98 A;  1RA8 A;  2ANO A;  4QLF A;  3FQZ A;  5HVB A;  1RX7 A;  2DHF A;  3KGY A;  3CSE A;  1OHK A;  4KAK A;  4EJ1 A;  4H96 A;  1D1G A;  2W3V A;  3QLX A;  5JA3 A;  4FGH A;  4ELH A;  3F0S X;  5ECX A;  1BOZ A;  3SRR X;  3I3R A;  4Q6A A;  1U70 A;  1DRF A;  1PDB A;  3UM6 A;  1RH3 A;  1RX1 A;  2XW7 A;  3KJR A;  3HJ3 A;  1DR6 A;  4M6L A;  2JYB A;  2W3M A;  3S3V A;  3NXX A;  1DR5 A;  2CIG A;  4OSG A;  3KY8 A;  4RGC A;  4KL9 A;  3TQB A;  1IA3 A;  3NXY A;  4KJJ A;  4P3Q A;  2C2T A;  3OAF A;  4PST A;  3JWC A;  4KD7 A;  1RX6 A;  4KNE A;  1U72 A;  4PSY A;  4XRB A;  3NU0 A;  3IRO A;  3GI2 A;  4X5J A;  4OR7 A;  1DYJ A;  1S3W A;  4P68 A;  1DRE A;  2OBC A;  1RA9 A;  3EIG A;  4DDR A;  3R33 A;  1RC4 A;  1HFQ A;  1ZDR A;  3RO9 A;  1RX9 A;  1M7A A;  4QLE A;  1J3J A;  2KGK A;  2W3W A;  1AOE A;  1DRA A;  3GHC A;  1DG5 A;  2BL9 A;  5JG0 X;  3DAT A;  1J3K A;  5HQY A;  3FL8 A;  3FS6 A;  2W9S A;  8DFR A;  3KJS A;  4QI9 A;  2FZI A;  1LY3 A;  2FZH A;  2D0K A;  3FYV X;  3FYW X;  2ANQ A;  1JOL A;  6DFR A;  1J3I A;  3QLW A;  4ELE A;  1DDS A;  3JVX A;  3KFY A;  1RB2 A;  3JWM A;  1LY4 A;  5HUI A;  4XEC X;  3FQF A;  4DPH A;  4FGG A;  1DHI A;  3QL3 A;  3OCH A;  4NX6 A;  3NZA X;  3TD8 A;  2INQ A;  1LUD A;  1RE7 A;  3SA2 A;  3EEJ A;  3EEK A;  2BLA A;  1SEJ A;  1JUV A;  3TQA A;  2P4G A;  4G95 A;  1DR2 A;  1KLK A;  3VCO A;  4DP3 A;  4XT6 A;  3NXV A;  2AZN A;  2OIP A;  3FRE X;  3F0V X;  2L28 A;  3IRM A;  2CD2 A;  4HA7 A;  5CC9 A;  4KY8 A;  3JWK A;  1DR1 A;  2HM9 A;  4XT5 A;  3NZD A;  3D80 A;  1JOM A;  2B3Z A;  3UM8 A;  2D5N A;  5HQZ A;  3SQY X;  4X5F A;  1DYH A;  3NZC X;  3SRW X;  1DRH A;  5HSR A;  5FDA A;  3F0X X;  3N0H A;  3SAI A;  3NXR A;  1RA3 A;  3FQC A;  3JWF A;  1DR3 A;  3QLZ A;  3JSU A;  3FY9 X;  1QZF A;  3EEM A;  4LAH X;  3JW3 A;  1DHF A;  3NXT A;  3QLS A;  4X5G A;  3NRR A;  4PSS A;  2GD9 A;  1RA1 A;  5EAJ A;  1DF7 A;  4G8Z X;  1RX8 A;  3E0B A;  4NX7 A;  4X5I A;  3RG9 A;  5HPB A;  1BZF A;  3IA4 A;  2QK8 A;  3QLY A;  3IX9 A;  4ELB A;  2W9T A;  5DXV A;  3K2H A;  1KMS A;  3FL9 A;  3F0U X;  7DFR A;  3ROA A;  3FRB X;  1PD8 A;  1S3Y A;  2HXV A;  4DPD A;  3CL9 A;  2G6V A;  3SH2 A;  3QYL A;  3HBB A;  1M78 A;  3SR5 X;  5U27 A;  2LF1 A;  3IRN A;  3GYF A;  2W3A A;  2ITH A;  1YHO A;  1IA4 A;  3FQ0 A;  5E8Q A;  2C2S A;  4KM2 A;  1AO8 A;  1DRB A;  1MVT A;  3NXO A;  3TQ8 A;  3DG8 A;  4HOF A;  1HFR A;  5DFR A;  3CLB A;  5CCC A;  3INV A;  1RA2 A;  1DDR A;  1DAJ A;  4KM0 A;  1IA2 A;  4ECK A;  4XT7 A;  4IXF X;  3SA1 A;  3NTZ A;  1S3U A;  4TU5 X;  2HQP A;  3F8Z A;  1KMV A;  1DIS A;  1DYI A;  4FHB A;  4M6J A;  1M79 A;  5HSU A;  4KJL A;  3LG4 A;  4QJZ D;  2DRC A;  4EIL A;  1VDR A;  2H2Q A;  1DIU A;  2O7P A;  5HF2 X;  4PTH A;  3Q1H A;  1U71 A;  4ELG A;  3F91 A;  4EIG A;  4KJK A;  3K47 A;  4DFR A;  5HT5 A;  3I8A X;  3JW5 A;  3FRA X;  4GH8 A;  3DRC A;  2BLC A;  4QJC A;  3F0B X;  4PDJ A;  1PD9 A;  3NZ6 X;  3QYO A;  3QFX A;  4KBN A;  3QG2 A;  3D84 X;  3QLR A;  1DLS A;  4HOE A;  2BLB A;  4IXG X;  4QHV A;  3FQV A;  4Q67 A;  1RG7 A;  5HT4 A;  3GHW A;  3DFR A;  1RF7 A;  4HOG A;  1S3V A;  1DHJ A;  4M7U A;  4KFJ A;  1RX2 A;  3NZB X;  1RD7 A;  1CD2 A;  3SGY A;  1DG7 A;  1DYR A;  3K74 A;  4ELF A;  1DLR A;  3QGT A;  1OHJ A;  1DR4 A;  4KY4 A;  1VJ3 A;  2W3B A;  4X5H A;  3FRD X;  4P66 A;  3GHV A;  3F8Y A;  1DG8 A;  3DGA A;  3DL6 A;  4I13 A;  4XT8 A;  4HA9 A;  4QLG A;  4KLX A;  4G3M A;  3TQ9 A;  3SRU X;  3QL0 A;  4KYA A;  3F0Q X;  3UM5 A;  3IA5 A;  4LAG X;  4EIZ A;  4IXE D;  5HI6 A;  3FY8 X;  4LEK X;  1RX5 A;  3M09 A;  1RB3 A;  4M2X A;  3S7A A;  3SRS X;  4PTJ A;  1TDR A;  2ZZA A;  3DAU A;  4H97 A;  3ZPC A;  3FQO A;  4Q0D A; 
#chains in the Genus database with same CATH homology
 3DL5 A;  1MVS A;  2W9G A;  5HF0 X;  4CD2 A;  5HVE A;  4Q0E A;  3L3R A;  3NZ9 X;  3EX8 A;  2FZJ A;  5ECC A;  3JTW A;  1AI9 A;  3EEL A;  1RX4 A;  4P3R A;  4XT4 A;  4H95 A;  1E26 A;  4I1N A;  1IA1 A;  3FRF X;  4XE6 X;  4M7V A;  1DR7 A;  3M08 A;  1HFP A;  1RX3 A;  3ZPG A;  4M6K A;  5U26 A;  1CZ3 A;  4KEB A;  3SRQ X;  3CD2 A;  3K45 A;  3S9U A;  2W9H A;  4LAE X;  4H98 A;  1RA8 A;  2ANO A;  4QLF A;  3FQZ A;  5HVB A;  1RX7 A;  2DHF A;  3KGY A;  3CSE A;  1OHK A;  4KAK A;  4EJ1 A;  4H96 A;  1D1G A;  2W3V A;  3QLX A;  5JA3 A;  4FGH A;  4ELH A;  3F0S X;  5ECX A;  1BOZ A;  3SRR X;  3I3R A;  4Q6A A;  1U70 A;  1DRF A;  1PDB A;  3UM6 A;  1RH3 A;  1RX1 A;  2XW7 A;  3KJR A;  3HJ3 A;  1DR6 A;  4M6L A;  2JYB A;  2W3M A;  3S3V A;  3NXX A;  1DR5 A;  2CIG A;  4OSG A;  3KY8 A;  4RGC A;  4KL9 A;  3TQB A;  1IA3 A;  3NXY A;  4KJJ A;  4P3Q A;  2C2T A;  3OAF A;  4PST A;  3JWC A;  4KD7 A;  1RX6 A;  4KNE A;  1U72 A;  4PSY A;  4XRB A;  3NU0 A;  3IRO A;  3GI2 A;  4X5J A;  4OR7 A;  1DYJ A;  1S3W A;  4P68 A;  1DRE A;  2OBC A;  1RA9 A;  3EIG A;  4DDR A;  3R33 A;  1RC4 A;  1HFQ A;  1ZDR A;  3RO9 A;  1RX9 A;  1M7A A;  4QLE A;  1J3J A;  2KGK A;  2W3W A;  1AOE A;  1DRA A;  3GHC A;  1DG5 A;  2BL9 A;  5JG0 X;  3DAT A;  1J3K A;  5HQY A;  3FL8 A;  3FS6 A;  2W9S A;  8DFR A;  3KJS A;  4QI9 A;  2FZI A;  1LY3 A;  2FZH A;  2D0K A;  3FYV X;  3FYW X;  2ANQ A;  1JOL A;  6DFR A;  1J3I A;  3QLW A;  4ELE A;  1DDS A;  3JVX A;  3KFY A;  1RB2 A;  3JWM A;  1LY4 A;  5HUI A;  4XEC X;  3FQF A;  4DPH A;  4FGG A;  1DHI A;  3QL3 A;  3OCH A;  4NX6 A;  3NZA X;  3TD8 A;  2INQ A;  1LUD A;  1RE7 A;  3SA2 A;  3EEJ A;  3EEK A;  2BLA A;  1SEJ A;  1JUV A;  3TQA A;  2P4G A;  4G95 A;  1DR2 A;  1KLK A;  3VCO A;  4DP3 A;  4XT6 A;  3NXV A;  2AZN A;  2OIP A;  3FRE X;  3F0V X;  2L28 A;  3IRM A;  2CD2 A;  4HA7 A;  5CC9 A;  4KY8 A;  3JWK A;  1DR1 A;  2HM9 A;  4XT5 A;  3NZD A;  3D80 A;  1JOM A;  2B3Z A;  3UM8 A;  2D5N A;  5HQZ A;  3SQY X;  4X5F A;  1DYH A;  3NZC X;  3SRW X;  1DRH A;  5HSR A;  5FDA A;  3F0X X;  3N0H A;  3SAI A;  3NXR A;  1RA3 A;  3FQC A;  3JWF A;  1DR3 A;  3QLZ A;  3JSU A;  3FY9 X;  1QZF A;  3EEM A;  4LAH X;  3JW3 A;  1DHF A;  3NXT A;  3QLS A;  4X5G A;  3NRR A;  4PSS A;  2GD9 A;  1RA1 A;  5EAJ A;  1DF7 A;  4G8Z X;  1RX8 A;  3E0B A;  4NX7 A;  4X5I A;  3RG9 A;  5HPB A;  1BZF A;  3IA4 A;  2QK8 A;  3QLY A;  3IX9 A;  4ELB A;  2W9T A;  5DXV A;  3K2H A;  1KMS A;  3FL9 A;  3F0U X;  7DFR A;  3ROA A;  3FRB X;  1PD8 A;  1S3Y A;  2HXV A;  4DPD A;  3CL9 A;  2G6V A;  3SH2 A;  3QYL A;  3HBB A;  1M78 A;  3SR5 X;  5U27 A;  2LF1 A;  3IRN A;  3GYF A;  2W3A A;  2ITH A;  1YHO A;  1IA4 A;  3FQ0 A;  5E8Q A;  2C2S A;  4KM2 A;  1AO8 A;  1DRB A;  1MVT A;  3NXO A;  3TQ8 A;  3DG8 A;  4HOF A;  1HFR A;  5DFR A;  3CLB A;  5CCC A;  3INV A;  1RA2 A;  1DDR A;  1DAJ A;  4KM0 A;  1IA2 A;  4ECK A;  4XT7 A;  4IXF X;  3SA1 A;  3NTZ A;  1S3U A;  4TU5 X;  2HQP A;  3F8Z A;  1KMV A;  1DIS A;  1DYI A;  4FHB A;  4M6J A;  1M79 A;  5HSU A;  4KJL A;  3LG4 A;  4QJZ D;  2DRC A;  4EIL A;  1VDR A;  2H2Q A;  1DIU A;  2O7P A;  5HF2 X;  4PTH A;  3Q1H A;  1U71 A;  4ELG A;  3F91 A;  4EIG A;  4KJK A;  3K47 A;  4DFR A;  5HT5 A;  3I8A X;  3JW5 A;  3FRA X;  4GH8 A;  3DRC A;  2BLC A;  4QJC A;  3F0B X;  4PDJ A;  1PD9 A;  3NZ6 X;  3QYO A;  3QFX A;  4KBN A;  3QG2 A;  3D84 X;  3QLR A;  1DLS A;  4HOE A;  2BLB A;  4IXG X;  4QHV A;  3FQV A;  4Q67 A;  1RG7 A;  5HT4 A;  3GHW A;  3DFR A;  1RF7 A;  4HOG A;  1S3V A;  1DHJ A;  4M7U A;  4KFJ A;  1RX2 A;  3NZB X;  1RD7 A;  1CD2 A;  3SGY A;  1DG7 A;  1DYR A;  3K74 A;  4ELF A;  1DLR A;  3QGT A;  1OHJ A;  1DR4 A;  4KY4 A;  1VJ3 A;  2W3B A;  4X5H A;  3FRD X;  4P66 A;  3GHV A;  3F8Y A;  1DG8 A;  3DGA A;  3DL6 A;  4I13 A;  4XT8 A;  4HA9 A;  4QLG A;  4KLX A;  4G3M A;  3TQ9 A;  3SRU X;  3QL0 A;  4KYA A;  3F0Q X;  3UM5 A;  3IA5 A;  4LAG X;  4EIZ A;  4IXE D;  5HI6 A;  3FY8 X;  4LEK X;  1RX5 A;  3M09 A;  1RB3 A;  4M2X A;  3S7A A;  3SRS X;  4PTJ A;  1TDR A;  2ZZA A;  3DAU A;  4H97 A;  3ZPC A;  3FQO A;  4Q0D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...