1BZFA

Nmr solution structure and dynamics of the complex of lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate, 22 structures
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
162
structure length
162
Chain Sequence
TAFLWAQDRDGLIGKDGHLPWHLPDDLHYFRAQTVGKIMVVGRRTYESFPKRPLPERTNVVLTHQEDYQAQGAVVVHDVAAVFAYAKQHPDQELVIAGGAQIFTAFKDDVDTLLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
pubmed rcsb
molecule tags Oxidoreductase
source organism Lactobacillus casei
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 32
structure length 162
sequence length 162
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1998-10-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1bzfA00
3NZ6X 3CSEA 3QFXA 5HVEA 3EEKA 5HQYA 3KJRA 1RA9A 2G6VA 4KFJA 3LG4A 4QJCA 3F0SX 4QI9A 1DYJA 4KEBA 1RB3A 3IA4A 1DIUA 4LAEX 3FS6A 4PDJA 2P4GA 1E26A 3EEJA 2CD2A 3SRSX 4DPHA 1RA1A 3IX9A 4DPDA 5E8QA 1MVSA 3K47A 4QLEA 3CLBA 2W3AA 5HQZA 1JOMA 1IA2A 2FZIA 3EELA 1IA1A 5HPBA 1DYRA 3JWKA 3GHWA 5HUIA 5HT5A 5HI6A 1KLKA 4IXGX 3ROAA 3TQ9A 4KJKA 1JOLA 1AO8A 4PSSA 4EILA 3KGYA 4EIGA 1RA2A 4PTJA 3QGTA 1SEJA 5ECCA 5U27A 3NTZA 1U72A 3KJSA 3SR5X 1J3JA 3JW3A 1DAJA 1DLSA 4H97A 3F0QX 3FQVA 5JA3A 3E0BA 3GI2A 4P68A 1RC4A 4QLGA 4FGHA 3NZBX 4Q0DA 4KM2A 5ECXA 4GH8A 3IRNA 2FZHA 3UM8A 1U70A 1S3YA 2W9SA 4PTHA 1RX5A 2KGKA 1CZ3A 4P3RA 1LY3A 4P66A 4X5IA 3QLSA 1DR3A 1JUVA 1D1GA 1PD8A 1U71A 5DFRA 3FQZA 4M6LA 4X5HA 3SAIA 1IA3A 1YHOA 3EEMA 4HOEA 1RX7A 1RX3A 3D80A 4KAKA 3FQCA 4QLFA 7DFRA 1KMVA 1DG8A 3M09A 3L3RA 4G8ZX 4ELEA 3D84X 3QL0A 6DFRA 3JWMA 3QLXA 1S3UA 2OIPA 4LEKX 3OAFA 2O7PA 3GYFA 1OHKA 4XECX 5DXVA 3SGYA 2W9GA 1RE7A 1DLRA 3N0HA 1AOEA 3NZ9X 5U26A 3JWFA 4ECKA 3ZPCA 2HQPA 1DR5A 3QG2A 1OHJA 3NRRA 4PSTA 2W3WA 4KY8A 4KNEA 1VDRA 3CL9A 4XT4A 3FRAX 3S9UA 4KJLA 4H95A 2FZJA 3DGAA 2ZZAA 3RO9A 4ELHA 1CD2A 3GHVA 3NXRA 2HXVA 3DRCA 1PD9A 3TQ8A 4RGCA 3JTWA 3NU0A 3QLWA 3FYVX 1AI9A 1HFRA 3QL3A 3IROA 1M79A 3QYOA 4IXFX 1DYIA 2W9HA 2W3VA 3F91A 2GD9A 4OSGA 1DRBA 1M78A 3EIGA 2BL9A 3JSUA 3TQBA 4PSYA 2HM9A 1RA3A 3NXXA 2L28A 3QYLA 1VJ3A 3I3RA 3M08A 1RD7A 2AZNA 3FY8X 3KY8A 3F0XX 3SA1A 1HFPA 1RX9A 4DFRA 1DREA 5CC9A 3DFRA 4HOGA 8DFRA 3QLZA 1DR7A 2BLAA 1MVTA 4XT8A 3DL5A 3EX8A 3IRMA 1DR2A 3TD8A 5HSRA 3RG9A 3JVXA 3Q1HA 3FRBX 1RB2A 2QK8A 4M6JA 4EIZA 3IA5A 4LAGX 3FRFX 3F0BX 3K74A 3FL8A 4XE6X 3NZAX 1KMSA 4HA7A 1RX2A 4X5JA 1BOZA 3SRQX 4IXED 1RX1A 1DDRA 2DHFA 4QJZD 3NXYA 2ANQA 2W9TA 1DR4A 3HJ3A 1DR1A 1DRFA 2XW7A 4XT6A 1IA4A 3QLRA 1DHIA 2DRCA 3HBBA 4KLXA 3OCHA 4I1NA 4FHBA 2B3ZA 4X5GA 3F8ZA 3JW5A 3SQYX 2BLBA 1DHJA 4KY4A 3SRRX 4CD2A 4G3MA 5EAJA 1LUDA 3DAUA 1DRHA 2JYBA 3INVA 1RX8A 3FQ0A 5JG0X 1RG7A 3FQFA 1DHFA 4ELGA 5CCCA 4XT5A 1DG7A 1DISA 2C2TA 4M7VA 4KL9A 1S3VA 4G95A 5HSUA 2ANOA 2ITHA 4QHVA 4LAHX 4EJ1A 2CIGA 1DDSA 1J3IA 4NX7A 4KJJA 2C2SA 4OR7A 3I8AX 2D0KA 3SA2A 3NZCX 1DG5A 1LY4A 4Q6AA 1QZFA 1M7AA 5HT4A 4FGGA 3FRDX 4KM0A 4XT7A 1DRAA 4KBNA 4DDRA 1BZFA 4I13A 3F0VX 4ELFA 5FDAA 3SH2A 1RA8A 3QLYA 1S3WA 2W3BA 3FQOA 1J3KA 1RX4A 3FY9X 3SRWX 2W3MA 1TDRA 5HF2X 1DF7A 3K2HA 4XRBA 4H98A 3F0UX 1PDBA 2LF1A 3JWCA 3DG8A 4DP3A 1DR6A 3R33A 1DYHA 3S7AA 3CD2A 3NZDA 3DATA 3FYWX 4NX6A 2OBCA 3NXTA 4TU5X 3F8YA 4M2XA 3VCOA 3FREX 4M6KA 1RX6A 3K45A 2D5NA 4Q67A 4Q0EA 1RF7A 3KFYA 3SRUX 3NXOA 4KYAA 2INQA 2H2QA 3DL6A 4HA9A 4KD7A 4X5FA 3UM6A 4HOFA 3GHCA 4H96A 3ZPGA 3UM5A 5HVBA 4P3QA 1ZDRA 1RH3A 4ELBA 2BLCA 4M7UA 1HFQA 3NXVA 3FL9A 3S3VA 5HF0X 3TQAA
chains in the Genus database with same CATH superfamily
3NZ6X 3CSEA 3QFXA 5HVEA 3EEKA 5HQYA 3KJRA 1RA9A 2G6VA 4KFJA 3LG4A 4QJCA 3F0SX 4QI9A 1DYJA 4KEBA 1RB3A 3IA4A 1DIUA 4LAEX 3FS6A 4PDJA 2P4GA 1E26A 3EEJA 2CD2A 3SRSX 4DPHA 1RA1A 3IX9A 4DPDA 5E8QA 1MVSA 3K47A 4QLEA 3CLBA 2W3AA 5HQZA 1JOMA 1IA2A 2FZIA 3EELA 1IA1A 5HPBA 1DYRA 3JWKA 3GHWA 5HUIA 5HT5A 5HI6A 1KLKA 4IXGX 3ROAA 3TQ9A 4KJKA 1JOLA 1AO8A 4PSSA 4EILA 3KGYA 4EIGA 1RA2A 4PTJA 3QGTA 1SEJA 5ECCA 5U27A 3NTZA 1U72A 3KJSA 3SR5X 1J3JA 3JW3A 1DAJA 1DLSA 4H97A 3F0QX 3FQVA 5JA3A 3E0BA 3GI2A 4P68A 1RC4A 4QLGA 4FGHA 3NZBX 4Q0DA 4KM2A 5ECXA 4GH8A 3IRNA 2FZHA 3UM8A 1U70A 1S3YA 2W9SA 4PTHA 1RX5A 2KGKA 1CZ3A 4P3RA 1LY3A 4P66A 4X5IA 3QLSA 1DR3A 1JUVA 1D1GA 1PD8A 1U71A 5DFRA 3FQZA 4M6LA 4X5HA 3SAIA 1IA3A 1YHOA 3EEMA 4HOEA 1RX7A 1RX3A 3D80A 4KAKA 3FQCA 4QLFA 7DFRA 1KMVA 1DG8A 3M09A 3L3RA 4G8ZX 4ELEA 3D84X 3QL0A 6DFRA 3JWMA 3QLXA 1S3UA 2OIPA 4LEKX 3OAFA 2O7PA 3GYFA 1OHKA 4XECX 5DXVA 3SGYA 2W9GA 1RE7A 1DLRA 3N0HA 1AOEA 3NZ9X 5U26A 3JWFA 4ECKA 3ZPCA 2HQPA 1DR5A 3QG2A 1OHJA 3NRRA 4PSTA 2W3WA 4KY8A 4KNEA 1VDRA 3CL9A 4XT4A 3FRAX 3S9UA 4KJLA 4H95A 2FZJA 3DGAA 2ZZAA 3RO9A 4ELHA 1CD2A 3GHVA 3NXRA 2HXVA 3DRCA 1PD9A 3TQ8A 4RGCA 3JTWA 3NU0A 3QLWA 3FYVX 1AI9A 1HFRA 3QL3A 3IROA 1M79A 3QYOA 4IXFX 1DYIA 2W9HA 2W3VA 3F91A 2GD9A 4OSGA 1DRBA 1M78A 3EIGA 2BL9A 3JSUA 3TQBA 4PSYA 2HM9A 1RA3A 3NXXA 2L28A 3QYLA 1VJ3A 3I3RA 3M08A 1RD7A 2AZNA 3FY8X 3KY8A 3F0XX 3SA1A 1HFPA 1RX9A 4DFRA 1DREA 5CC9A 3DFRA 4HOGA 8DFRA 3QLZA 1DR7A 2BLAA 1MVTA 4XT8A 3DL5A 3EX8A 3IRMA 1DR2A 3TD8A 5HSRA 3RG9A 3JVXA 3Q1HA 3FRBX 1RB2A 2QK8A 4M6JA 4EIZA 3IA5A 4LAGX 3FRFX 3F0BX 3K74A 3FL8A 4XE6X 3NZAX 1KMSA 4HA7A 1RX2A 4X5JA 1BOZA 3SRQX 4IXED 1RX1A 1DDRA 2DHFA 4QJZD 3NXYA 2ANQA 2W9TA 1DR4A 3HJ3A 1DR1A 1DRFA 2XW7A 4XT6A 1IA4A 3QLRA 1DHIA 2DRCA 3HBBA 4KLXA 3OCHA 4I1NA 4FHBA 2B3ZA 4X5GA 3F8ZA 3JW5A 3SQYX 2BLBA 1DHJA 4KY4A 3SRRX 4CD2A 4G3MA 5EAJA 1LUDA 3DAUA 1DRHA 2JYBA 3INVA 1RX8A 3FQ0A 5JG0X 1RG7A 3FQFA 1DHFA 4ELGA 5CCCA 4XT5A 1DG7A 1DISA 2C2TA 4M7VA 4KL9A 1S3VA 4G95A 5HSUA 2ANOA 2ITHA 4QHVA 4LAHX 4EJ1A 2CIGA 1DDSA 1J3IA 4NX7A 4KJJA 2C2SA 4OR7A 3I8AX 2D0KA 3SA2A 3NZCX 1DG5A 1LY4A 4Q6AA 1QZFA 1M7AA 5HT4A 4FGGA 3FRDX 4KM0A 4XT7A 1DRAA 4KBNA 4DDRA 1BZFA 4I13A 3F0VX 4ELFA 5FDAA 3SH2A 1RA8A 3QLYA 1S3WA 2W3BA 3FQOA 1J3KA 1RX4A 3FY9X 3SRWX 2W3MA 1TDRA 5HF2X 1DF7A 3K2HA 4XRBA 4H98A 3F0UX 1PDBA 2LF1A 3JWCA 3DG8A 4DP3A 1DR6A 3R33A 1DYHA 3S7AA 3CD2A 3NZDA 3DATA 3FYWX 4NX6A 2OBCA 3NXTA 4TU5X 3F8YA 4M2XA 3VCOA 3FREX 4M6KA 1RX6A 3K45A 2D5NA 4Q67A 4Q0EA 1RF7A 3KFYA 3SRUX 3NXOA 4KYAA 2INQA 2H2QA 3DL6A 4HA9A 4KD7A 4X5FA 3UM6A 4HOFA 3GHCA 4H96A 3ZPGA 3UM5A 5HVBA 4P3QA 1ZDRA 1RH3A 4ELBA 2BLCA 4M7UA 1HFQA 3NXVA 3FL9A 3S3VA 5HF0X 3TQAA
chains in the Genus database with same CATH topology
3NZ6X 3CSEA 3QFXA 5HVEA 3EEKA 5HQYA 3KJRA 1RA9A 2G6VA 4KFJA 3LG4A 4QJCA 3F0SX 4QI9A 1DYJA 4KEBA 1RB3A 3IA4A 1DIUA 4LAEX 3FS6A 4PDJA 2P4GA 1E26A 3EEJA 2CD2A 3SRSX 4DPHA 1RA1A 3IX9A 4DPDA 5E8QA 1MVSA 3K47A 4QLEA 3CLBA 2W3AA 5HQZA 1JOMA 1IA2A 2FZIA 3EELA 1IA1A 5HPBA 1DYRA 3JWKA 3GHWA 5HUIA 5HT5A 5HI6A 1KLKA 4IXGX 3ROAA 3TQ9A 4KJKA 1JOLA 1AO8A 4PSSA 4EILA 3KGYA 4EIGA 1RA2A 4PTJA 3QGTA 1SEJA 5ECCA 5U27A 3NTZA 1U72A 3KJSA 3SR5X 1J3JA 3JW3A 1DAJA 1DLSA 4H97A 3F0QX 3FQVA 5JA3A 3E0BA 3GI2A 4P68A 1RC4A 4QLGA 4FGHA 3NZBX 4Q0DA 4KM2A 5ECXA 4GH8A 3IRNA 2FZHA 3UM8A 1U70A 1S3YA 2W9SA 4PTHA 1RX5A 2KGKA 1CZ3A 4P3RA 1LY3A 4P66A 4X5IA 3QLSA 1DR3A 1JUVA 1D1GA 1PD8A 1U71A 5DFRA 3FQZA 4M6LA 4X5HA 3SAIA 1IA3A 1YHOA 3EEMA 4HOEA 1RX7A 1RX3A 3D80A 4KAKA 3FQCA 4QLFA 7DFRA 1KMVA 1DG8A 3M09A 3L3RA 4G8ZX 4ELEA 3D84X 3QL0A 6DFRA 3JWMA 3QLXA 1S3UA 2OIPA 4LEKX 3OAFA 2O7PA 3GYFA 1OHKA 4XECX 5DXVA 3SGYA 2W9GA 1RE7A 1DLRA 3N0HA 1AOEA 3NZ9X 5U26A 3JWFA 4ECKA 3ZPCA 2HQPA 1DR5A 3QG2A 1OHJA 3NRRA 4PSTA 2W3WA 4KY8A 4KNEA 1VDRA 3CL9A 4XT4A 3FRAX 3S9UA 4KJLA 4H95A 2FZJA 3DGAA 2ZZAA 3RO9A 4ELHA 1CD2A 3GHVA 3NXRA 2HXVA 3DRCA 1PD9A 3TQ8A 4RGCA 3JTWA 3NU0A 3QLWA 3FYVX 1AI9A 1HFRA 3QL3A 3IROA 1M79A 3QYOA 4IXFX 1DYIA 2W9HA 2W3VA 3F91A 2GD9A 4OSGA 1DRBA 1M78A 3EIGA 2BL9A 3JSUA 3TQBA 4PSYA 2HM9A 1RA3A 3NXXA 2L28A 3QYLA 1VJ3A 3I3RA 3M08A 1RD7A 2AZNA 3FY8X 3KY8A 3F0XX 3SA1A 1HFPA 1RX9A 4DFRA 1DREA 5CC9A 3DFRA 4HOGA 8DFRA 3QLZA 1DR7A 2BLAA 1MVTA 4XT8A 3DL5A 3EX8A 3IRMA 1DR2A 3TD8A 5HSRA 3RG9A 3JVXA 3Q1HA 3FRBX 1RB2A 2QK8A 4M6JA 4EIZA 3IA5A 4LAGX 3FRFX 3F0BX 3K74A 3FL8A 4XE6X 3NZAX 1KMSA 4HA7A 1RX2A 4X5JA 1BOZA 3SRQX 4IXED 1RX1A 1DDRA 2DHFA 4QJZD 3NXYA 2ANQA 2W9TA 1DR4A 3HJ3A 1DR1A 1DRFA 2XW7A 4XT6A 1IA4A 3QLRA 1DHIA 2DRCA 3HBBA 4KLXA 3OCHA 4I1NA 4FHBA 2B3ZA 4X5GA 3F8ZA 3JW5A 3SQYX 2BLBA 1DHJA 4KY4A 3SRRX 4CD2A 4G3MA 5EAJA 1LUDA 3DAUA 1DRHA 2JYBA 3INVA 1RX8A 3FQ0A 5JG0X 1RG7A 3FQFA 1DHFA 4ELGA 5CCCA 4XT5A 1DG7A 1DISA 2C2TA 4M7VA 4KL9A 1S3VA 4G95A 5HSUA 2ANOA 2ITHA 4QHVA 4LAHX 4EJ1A 2CIGA 1DDSA 1J3IA 4NX7A 4KJJA 2C2SA 4OR7A 3I8AX 2D0KA 3SA2A 3NZCX 1DG5A 1LY4A 4Q6AA 1QZFA 1M7AA 5HT4A 4FGGA 3FRDX 4KM0A 4XT7A 1DRAA 4KBNA 4DDRA 1BZFA 4I13A 3F0VX 4ELFA 5FDAA 3SH2A 1RA8A 3QLYA 1S3WA 2W3BA 3FQOA 1J3KA 1RX4A 3FY9X 3SRWX 2W3MA 1TDRA 5HF2X 1DF7A 3K2HA 4XRBA 4H98A 3F0UX 1PDBA 2LF1A 3JWCA 3DG8A 4DP3A 1DR6A 3R33A 1DYHA 3S7AA 3CD2A 3NZDA 3DATA 3FYWX 4NX6A 2OBCA 3NXTA 4TU5X 3F8YA 4M2XA 3VCOA 3FREX 4M6KA 1RX6A 3K45A 2D5NA 4Q67A 4Q0EA 1RF7A 3KFYA 3SRUX 3NXOA 4KYAA 2INQA 2H2QA 3DL6A 4HA9A 4KD7A 4X5FA 3UM6A 4HOFA 3GHCA 4H96A 3ZPGA 3UM5A 5HVBA 4P3QA 1ZDRA 1RH3A 4ELBA 2BLCA 4M7UA 1HFQA 3NXVA 3FL9A 3S3VA 5HF0X 3TQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZ6 X;  3CSE A;  3QFX A;  5HVE A;  3EEK A;  5HQY A;  3KJR A;  1RA9 A;  2G6V A;  4KFJ A;  3LG4 A;  4QJC A;  3F0S X;  4QI9 A;  1DYJ A;  4KEB A;  1RB3 A;  3IA4 A;  1DIU A;  4LAE X;  3FS6 A;  4PDJ A;  2P4G A;  1E26 A;  3EEJ A;  2CD2 A;  3SRS X;  4DPH A;  1RA1 A;  3IX9 A;  4DPD A;  5E8Q A;  1MVS A;  3K47 A;  4QLE A;  3CLB A;  2W3A A;  5HQZ A;  1JOM A;  1IA2 A;  2FZI A;  3EEL A;  1IA1 A;  5HPB A;  1DYR A;  3JWK A;  3GHW A;  5HUI A;  5HT5 A;  5HI6 A;  1KLK A;  4IXG X;  3ROA A;  3TQ9 A;  4KJK A;  1JOL A;  1AO8 A;  4PSS A;  4EIL A;  3KGY A;  4EIG A;  1RA2 A;  4PTJ A;  3QGT A;  1SEJ A;  5ECC A;  5U27 A;  3NTZ A;  1U72 A;  3KJS A;  3SR5 X;  1J3J A;  3JW3 A;  1DAJ A;  1DLS A;  4H97 A;  3F0Q X;  3FQV A;  5JA3 A;  3E0B A;  3GI2 A;  4P68 A;  1RC4 A;  4QLG A;  4FGH A;  3NZB X;  4Q0D A;  4KM2 A;  5ECX A;  4GH8 A;  3IRN A;  2FZH A;  3UM8 A;  1U70 A;  1S3Y A;  2W9S A;  4PTH A;  1RX5 A;  2KGK A;  1CZ3 A;  4P3R A;  1LY3 A;  4P66 A;  4X5I A;  3QLS A;  1DR3 A;  1JUV A;  1D1G A;  1PD8 A;  1U71 A;  5DFR A;  3FQZ A;  4M6L A;  4X5H A;  3SAI A;  1IA3 A;  1YHO A;  3EEM A;  4HOE A;  1RX7 A;  1RX3 A;  3D80 A;  4KAK A;  3FQC A;  4QLF A;  7DFR A;  1KMV A;  1DG8 A;  3M09 A;  3L3R A;  4G8Z X;  4ELE A;  3D84 X;  3QL0 A;  6DFR A;  3JWM A;  3QLX A;  1S3U A;  2OIP A;  4LEK X;  3OAF A;  2O7P A;  3GYF A;  1OHK A;  4XEC X;  5DXV A;  3SGY A;  2W9G A;  1RE7 A;  1DLR A;  3N0H A;  1AOE A;  3NZ9 X;  5U26 A;  3JWF A;  4ECK A;  3ZPC A;  2HQP A;  1DR5 A;  3QG2 A;  1OHJ A;  3NRR A;  4PST A;  2W3W A;  4KY8 A;  4KNE A;  1VDR A;  3CL9 A;  4XT4 A;  3FRA X;  3S9U A;  4KJL A;  4H95 A;  2FZJ A;  3DGA A;  2ZZA A;  3RO9 A;  4ELH A;  1CD2 A;  3GHV A;  3NXR A;  2HXV A;  3DRC A;  1PD9 A;  3TQ8 A;  4RGC A;  3JTW A;  3NU0 A;  3QLW A;  3FYV X;  1AI9 A;  1HFR A;  3QL3 A;  3IRO A;  1M79 A;  3QYO A;  4IXF X;  1DYI A;  2W9H A;  2W3V A;  3F91 A;  2GD9 A;  4OSG A;  1DRB A;  1M78 A;  3EIG A;  2BL9 A;  3JSU A;  3TQB A;  4PSY A;  2HM9 A;  1RA3 A;  3NXX A;  2L28 A;  3QYL A;  1VJ3 A;  3I3R A;  3M08 A;  1RD7 A;  2AZN A;  3FY8 X;  3KY8 A;  3F0X X;  3SA1 A;  1HFP A;  1RX9 A;  4DFR A;  1DRE A;  5CC9 A;  3DFR A;  4HOG A;  8DFR A;  3QLZ A;  1DR7 A;  2BLA A;  1MVT A;  4XT8 A;  3DL5 A;  3EX8 A;  3IRM A;  1DR2 A;  3TD8 A;  5HSR A;  3RG9 A;  3JVX A;  3Q1H A;  3FRB X;  1RB2 A;  2QK8 A;  4M6J A;  4EIZ A;  3IA5 A;  4LAG X;  3FRF X;  3F0B X;  3K74 A;  3FL8 A;  4XE6 X;  3NZA X;  1KMS A;  4HA7 A;  1RX2 A;  4X5J A;  1BOZ A;  3SRQ X;  4IXE D;  1RX1 A;  1DDR A;  2DHF A;  4QJZ D;  3NXY A;  2ANQ A;  2W9T A;  1DR4 A;  3HJ3 A;  1DR1 A;  1DRF A;  2XW7 A;  4XT6 A;  1IA4 A;  3QLR A;  1DHI A;  2DRC A;  3HBB A;  4KLX A;  3OCH A;  4I1N A;  4FHB A;  2B3Z A;  4X5G A;  3F8Z A;  3JW5 A;  3SQY X;  2BLB A;  1DHJ A;  4KY4 A;  3SRR X;  4CD2 A;  4G3M A;  5EAJ A;  1LUD A;  3DAU A;  1DRH A;  2JYB A;  3INV A;  1RX8 A;  3FQ0 A;  5JG0 X;  1RG7 A;  3FQF A;  1DHF A;  4ELG A;  5CCC A;  4XT5 A;  1DG7 A;  1DIS A;  2C2T A;  4M7V A;  4KL9 A;  1S3V A;  4G95 A;  5HSU A;  2ANO A;  2ITH A;  4QHV A;  4LAH X;  4EJ1 A;  2CIG A;  1DDS A;  1J3I A;  4NX7 A;  4KJJ A;  2C2S A;  4OR7 A;  3I8A X;  2D0K A;  3SA2 A;  3NZC X;  1DG5 A;  1LY4 A;  4Q6A A;  1QZF A;  1M7A A;  5HT4 A;  4FGG A;  3FRD X;  4KM0 A;  4XT7 A;  1DRA A;  4KBN A;  4DDR A;  1BZF A;  4I13 A;  3F0V X;  4ELF A;  5FDA A;  3SH2 A;  1RA8 A;  3QLY A;  1S3W A;  2W3B A;  3FQO A;  1J3K A;  1RX4 A;  3FY9 X;  3SRW X;  2W3M A;  1TDR A;  5HF2 X;  1DF7 A;  3K2H A;  4XRB A;  4H98 A;  3F0U X;  1PDB A;  2LF1 A;  3JWC A;  3DG8 A;  4DP3 A;  1DR6 A;  3R33 A;  1DYH A;  3S7A A;  3CD2 A;  3NZD A;  3DAT A;  3FYW X;  4NX6 A;  2OBC A;  3NXT A;  4TU5 X;  3F8Y A;  4M2X A;  3VCO A;  3FRE X;  4M6K A;  1RX6 A;  3K45 A;  2D5N A;  4Q67 A;  4Q0E A;  1RF7 A;  3KFY A;  3SRU X;  3NXO A;  4KYA A;  2INQ A;  2H2Q A;  3DL6 A;  4HA9 A;  4KD7 A;  4X5F A;  3UM6 A;  4HOF A;  3GHC A;  4H96 A;  3ZPG A;  3UM5 A;  5HVB A;  4P3Q A;  1ZDR A;  1RH3 A;  4ELB A;  2BLC A;  4M7U A;  1HFQ A;  3NXV A;  3FL9 A;  3S3V A;  5HF0 X;  3TQA A; 
#chains in the Genus database with same CATH topology
 3NZ6 X;  3CSE A;  3QFX A;  5HVE A;  3EEK A;  5HQY A;  3KJR A;  1RA9 A;  2G6V A;  4KFJ A;  3LG4 A;  4QJC A;  3F0S X;  4QI9 A;  1DYJ A;  4KEB A;  1RB3 A;  3IA4 A;  1DIU A;  4LAE X;  3FS6 A;  4PDJ A;  2P4G A;  1E26 A;  3EEJ A;  2CD2 A;  3SRS X;  4DPH A;  1RA1 A;  3IX9 A;  4DPD A;  5E8Q A;  1MVS A;  3K47 A;  4QLE A;  3CLB A;  2W3A A;  5HQZ A;  1JOM A;  1IA2 A;  2FZI A;  3EEL A;  1IA1 A;  5HPB A;  1DYR A;  3JWK A;  3GHW A;  5HUI A;  5HT5 A;  5HI6 A;  1KLK A;  4IXG X;  3ROA A;  3TQ9 A;  4KJK A;  1JOL A;  1AO8 A;  4PSS A;  4EIL A;  3KGY A;  4EIG A;  1RA2 A;  4PTJ A;  3QGT A;  1SEJ A;  5ECC A;  5U27 A;  3NTZ A;  1U72 A;  3KJS A;  3SR5 X;  1J3J A;  3JW3 A;  1DAJ A;  1DLS A;  4H97 A;  3F0Q X;  3FQV A;  5JA3 A;  3E0B A;  3GI2 A;  4P68 A;  1RC4 A;  4QLG A;  4FGH A;  3NZB X;  4Q0D A;  4KM2 A;  5ECX A;  4GH8 A;  3IRN A;  2FZH A;  3UM8 A;  1U70 A;  1S3Y A;  2W9S A;  4PTH A;  1RX5 A;  2KGK A;  1CZ3 A;  4P3R A;  1LY3 A;  4P66 A;  4X5I A;  3QLS A;  1DR3 A;  1JUV A;  1D1G A;  1PD8 A;  1U71 A;  5DFR A;  3FQZ A;  4M6L A;  4X5H A;  3SAI A;  1IA3 A;  1YHO A;  3EEM A;  4HOE A;  1RX7 A;  1RX3 A;  3D80 A;  4KAK A;  3FQC A;  4QLF A;  7DFR A;  1KMV A;  1DG8 A;  3M09 A;  3L3R A;  4G8Z X;  4ELE A;  3D84 X;  3QL0 A;  6DFR A;  3JWM A;  3QLX A;  1S3U A;  2OIP A;  4LEK X;  3OAF A;  2O7P A;  3GYF A;  1OHK A;  4XEC X;  5DXV A;  3SGY A;  2W9G A;  1RE7 A;  1DLR A;  3N0H A;  1AOE A;  3NZ9 X;  5U26 A;  3JWF A;  4ECK A;  3ZPC A;  2HQP A;  1DR5 A;  3QG2 A;  1OHJ A;  3NRR A;  4PST A;  2W3W A;  4KY8 A;  4KNE A;  1VDR A;  3CL9 A;  4XT4 A;  3FRA X;  3S9U A;  4KJL A;  4H95 A;  2FZJ A;  3DGA A;  2ZZA A;  3RO9 A;  4ELH A;  1CD2 A;  3GHV A;  3NXR A;  2HXV A;  3DRC A;  1PD9 A;  3TQ8 A;  4RGC A;  3JTW A;  3NU0 A;  3QLW A;  3FYV X;  1AI9 A;  1HFR A;  3QL3 A;  3IRO A;  1M79 A;  3QYO A;  4IXF X;  1DYI A;  2W9H A;  2W3V A;  3F91 A;  2GD9 A;  4OSG A;  1DRB A;  1M78 A;  3EIG A;  2BL9 A;  3JSU A;  3TQB A;  4PSY A;  2HM9 A;  1RA3 A;  3NXX A;  2L28 A;  3QYL A;  1VJ3 A;  3I3R A;  3M08 A;  1RD7 A;  2AZN A;  3FY8 X;  3KY8 A;  3F0X X;  3SA1 A;  1HFP A;  1RX9 A;  4DFR A;  1DRE A;  5CC9 A;  3DFR A;  4HOG A;  8DFR A;  3QLZ A;  1DR7 A;  2BLA A;  1MVT A;  4XT8 A;  3DL5 A;  3EX8 A;  3IRM A;  1DR2 A;  3TD8 A;  5HSR A;  3RG9 A;  3JVX A;  3Q1H A;  3FRB X;  1RB2 A;  2QK8 A;  4M6J A;  4EIZ A;  3IA5 A;  4LAG X;  3FRF X;  3F0B X;  3K74 A;  3FL8 A;  4XE6 X;  3NZA X;  1KMS A;  4HA7 A;  1RX2 A;  4X5J A;  1BOZ A;  3SRQ X;  4IXE D;  1RX1 A;  1DDR A;  2DHF A;  4QJZ D;  3NXY A;  2ANQ A;  2W9T A;  1DR4 A;  3HJ3 A;  1DR1 A;  1DRF A;  2XW7 A;  4XT6 A;  1IA4 A;  3QLR A;  1DHI A;  2DRC A;  3HBB A;  4KLX A;  3OCH A;  4I1N A;  4FHB A;  2B3Z A;  4X5G A;  3F8Z A;  3JW5 A;  3SQY X;  2BLB A;  1DHJ A;  4KY4 A;  3SRR X;  4CD2 A;  4G3M A;  5EAJ A;  1LUD A;  3DAU A;  1DRH A;  2JYB A;  3INV A;  1RX8 A;  3FQ0 A;  5JG0 X;  1RG7 A;  3FQF A;  1DHF A;  4ELG A;  5CCC A;  4XT5 A;  1DG7 A;  1DIS A;  2C2T A;  4M7V A;  4KL9 A;  1S3V A;  4G95 A;  5HSU A;  2ANO A;  2ITH A;  4QHV A;  4LAH X;  4EJ1 A;  2CIG A;  1DDS A;  1J3I A;  4NX7 A;  4KJJ A;  2C2S A;  4OR7 A;  3I8A X;  2D0K A;  3SA2 A;  3NZC X;  1DG5 A;  1LY4 A;  4Q6A A;  1QZF A;  1M7A A;  5HT4 A;  4FGG A;  3FRD X;  4KM0 A;  4XT7 A;  1DRA A;  4KBN A;  4DDR A;  1BZF A;  4I13 A;  3F0V X;  4ELF A;  5FDA A;  3SH2 A;  1RA8 A;  3QLY A;  1S3W A;  2W3B A;  3FQO A;  1J3K A;  1RX4 A;  3FY9 X;  3SRW X;  2W3M A;  1TDR A;  5HF2 X;  1DF7 A;  3K2H A;  4XRB A;  4H98 A;  3F0U X;  1PDB A;  2LF1 A;  3JWC A;  3DG8 A;  4DP3 A;  1DR6 A;  3R33 A;  1DYH A;  3S7A A;  3CD2 A;  3NZD A;  3DAT A;  3FYW X;  4NX6 A;  2OBC A;  3NXT A;  4TU5 X;  3F8Y A;  4M2X A;  3VCO A;  3FRE X;  4M6K A;  1RX6 A;  3K45 A;  2D5N A;  4Q67 A;  4Q0E A;  1RF7 A;  3KFY A;  3SRU X;  3NXO A;  4KYA A;  2INQ A;  2H2Q A;  3DL6 A;  4HA9 A;  4KD7 A;  4X5F A;  3UM6 A;  4HOF A;  3GHC A;  4H96 A;  3ZPG A;  3UM5 A;  5HVB A;  4P3Q A;  1ZDR A;  1RH3 A;  4ELB A;  2BLC A;  4M7U A;  1HFQ A;  3NXV A;  3FL9 A;  3S3V A;  5HF0 X;  3TQA A; 
#chains in the Genus database with same CATH homology
 3NZ6 X;  3CSE A;  3QFX A;  5HVE A;  3EEK A;  5HQY A;  3KJR A;  1RA9 A;  2G6V A;  4KFJ A;  3LG4 A;  4QJC A;  3F0S X;  4QI9 A;  1DYJ A;  4KEB A;  1RB3 A;  3IA4 A;  1DIU A;  4LAE X;  3FS6 A;  4PDJ A;  2P4G A;  1E26 A;  3EEJ A;  2CD2 A;  3SRS X;  4DPH A;  1RA1 A;  3IX9 A;  4DPD A;  5E8Q A;  1MVS A;  3K47 A;  4QLE A;  3CLB A;  2W3A A;  5HQZ A;  1JOM A;  1IA2 A;  2FZI A;  3EEL A;  1IA1 A;  5HPB A;  1DYR A;  3JWK A;  3GHW A;  5HUI A;  5HT5 A;  5HI6 A;  1KLK A;  4IXG X;  3ROA A;  3TQ9 A;  4KJK A;  1JOL A;  1AO8 A;  4PSS A;  4EIL A;  3KGY A;  4EIG A;  1RA2 A;  4PTJ A;  3QGT A;  1SEJ A;  5ECC A;  5U27 A;  3NTZ A;  1U72 A;  3KJS A;  3SR5 X;  1J3J A;  3JW3 A;  1DAJ A;  1DLS A;  4H97 A;  3F0Q X;  3FQV A;  5JA3 A;  3E0B A;  3GI2 A;  4P68 A;  1RC4 A;  4QLG A;  4FGH A;  3NZB X;  4Q0D A;  4KM2 A;  5ECX A;  4GH8 A;  3IRN A;  2FZH A;  3UM8 A;  1U70 A;  1S3Y A;  2W9S A;  4PTH A;  1RX5 A;  2KGK A;  1CZ3 A;  4P3R A;  1LY3 A;  4P66 A;  4X5I A;  3QLS A;  1DR3 A;  1JUV A;  1D1G A;  1PD8 A;  1U71 A;  5DFR A;  3FQZ A;  4M6L A;  4X5H A;  3SAI A;  1IA3 A;  1YHO A;  3EEM A;  4HOE A;  1RX7 A;  1RX3 A;  3D80 A;  4KAK A;  3FQC A;  4QLF A;  7DFR A;  1KMV A;  1DG8 A;  3M09 A;  3L3R A;  4G8Z X;  4ELE A;  3D84 X;  3QL0 A;  6DFR A;  3JWM A;  3QLX A;  1S3U A;  2OIP A;  4LEK X;  3OAF A;  2O7P A;  3GYF A;  1OHK A;  4XEC X;  5DXV A;  3SGY A;  2W9G A;  1RE7 A;  1DLR A;  3N0H A;  1AOE A;  3NZ9 X;  5U26 A;  3JWF A;  4ECK A;  3ZPC A;  2HQP A;  1DR5 A;  3QG2 A;  1OHJ A;  3NRR A;  4PST A;  2W3W A;  4KY8 A;  4KNE A;  1VDR A;  3CL9 A;  4XT4 A;  3FRA X;  3S9U A;  4KJL A;  4H95 A;  2FZJ A;  3DGA A;  2ZZA A;  3RO9 A;  4ELH A;  1CD2 A;  3GHV A;  3NXR A;  2HXV A;  3DRC A;  1PD9 A;  3TQ8 A;  4RGC A;  3JTW A;  3NU0 A;  3QLW A;  3FYV X;  1AI9 A;  1HFR A;  3QL3 A;  3IRO A;  1M79 A;  3QYO A;  4IXF X;  1DYI A;  2W9H A;  2W3V A;  3F91 A;  2GD9 A;  4OSG A;  1DRB A;  1M78 A;  3EIG A;  2BL9 A;  3JSU A;  3TQB A;  4PSY A;  2HM9 A;  1RA3 A;  3NXX A;  2L28 A;  3QYL A;  1VJ3 A;  3I3R A;  3M08 A;  1RD7 A;  2AZN A;  3FY8 X;  3KY8 A;  3F0X X;  3SA1 A;  1HFP A;  1RX9 A;  4DFR A;  1DRE A;  5CC9 A;  3DFR A;  4HOG A;  8DFR A;  3QLZ A;  1DR7 A;  2BLA A;  1MVT A;  4XT8 A;  3DL5 A;  3EX8 A;  3IRM A;  1DR2 A;  3TD8 A;  5HSR A;  3RG9 A;  3JVX A;  3Q1H A;  3FRB X;  1RB2 A;  2QK8 A;  4M6J A;  4EIZ A;  3IA5 A;  4LAG X;  3FRF X;  3F0B X;  3K74 A;  3FL8 A;  4XE6 X;  3NZA X;  1KMS A;  4HA7 A;  1RX2 A;  4X5J A;  1BOZ A;  3SRQ X;  4IXE D;  1RX1 A;  1DDR A;  2DHF A;  4QJZ D;  3NXY A;  2ANQ A;  2W9T A;  1DR4 A;  3HJ3 A;  1DR1 A;  1DRF A;  2XW7 A;  4XT6 A;  1IA4 A;  3QLR A;  1DHI A;  2DRC A;  3HBB A;  4KLX A;  3OCH A;  4I1N A;  4FHB A;  2B3Z A;  4X5G A;  3F8Z A;  3JW5 A;  3SQY X;  2BLB A;  1DHJ A;  4KY4 A;  3SRR X;  4CD2 A;  4G3M A;  5EAJ A;  1LUD A;  3DAU A;  1DRH A;  2JYB A;  3INV A;  1RX8 A;  3FQ0 A;  5JG0 X;  1RG7 A;  3FQF A;  1DHF A;  4ELG A;  5CCC A;  4XT5 A;  1DG7 A;  1DIS A;  2C2T A;  4M7V A;  4KL9 A;  1S3V A;  4G95 A;  5HSU A;  2ANO A;  2ITH A;  4QHV A;  4LAH X;  4EJ1 A;  2CIG A;  1DDS A;  1J3I A;  4NX7 A;  4KJJ A;  2C2S A;  4OR7 A;  3I8A X;  2D0K A;  3SA2 A;  3NZC X;  1DG5 A;  1LY4 A;  4Q6A A;  1QZF A;  1M7A A;  5HT4 A;  4FGG A;  3FRD X;  4KM0 A;  4XT7 A;  1DRA A;  4KBN A;  4DDR A;  1BZF A;  4I13 A;  3F0V X;  4ELF A;  5FDA A;  3SH2 A;  1RA8 A;  3QLY A;  1S3W A;  2W3B A;  3FQO A;  1J3K A;  1RX4 A;  3FY9 X;  3SRW X;  2W3M A;  1TDR A;  5HF2 X;  1DF7 A;  3K2H A;  4XRB A;  4H98 A;  3F0U X;  1PDB A;  2LF1 A;  3JWC A;  3DG8 A;  4DP3 A;  1DR6 A;  3R33 A;  1DYH A;  3S7A A;  3CD2 A;  3NZD A;  3DAT A;  3FYW X;  4NX6 A;  2OBC A;  3NXT A;  4TU5 X;  3F8Y A;  4M2X A;  3VCO A;  3FRE X;  4M6K A;  1RX6 A;  3K45 A;  2D5N A;  4Q67 A;  4Q0E A;  1RF7 A;  3KFY A;  3SRU X;  3NXO A;  4KYA A;  2INQ A;  2H2Q A;  3DL6 A;  4HA9 A;  4KD7 A;  4X5F A;  3UM6 A;  4HOF A;  3GHC A;  4H96 A;  3ZPG A;  3UM5 A;  5HVB A;  4P3Q A;  1ZDR A;  1RH3 A;  4ELB A;  2BLC A;  4M7U A;  1HFQ A;  3NXV A;  3FL9 A;  3S3V A;  5HF0 X;  3TQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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