1CZ3A

Dihydrofolate reductase from thermotoga maritima
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
164
structure length
164
Chain Sequence
AKVIFVLAMDVSGKIASSVESWSSFEDRKNFRKITTEIGNVVMGRITFEEIGRPLPERLNVVLTRRPKTSNNPSLVFFNGSPADVVKFLEGKGYERVAVIGGKTVFTEFLREKLVDELFVTVEPYVFGKGIPFFDEFEGYFPLKLLEMRRLNERGTLFLKYSVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Thermotoga maritima
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 48
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1999-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1cz3A00
4QHVA 3SR5X 3QLZA 1LY3A 3F0SX 5HT5A 2C2TA 1RX6A 3QLXA 4PTHA 4XT8A 1DREA 3S9UA 4ELGA 3JVXA 4KYAA 1RX2A 1HFQA 3M09A 4EIZA 3UM8A 4XE6X 1DR1A 3VCOA 3M08A 3EEKA 3QG2A 2BLCA 1PDBA 3F8ZA 3TQBA 2HM9A 1J3JA 2P4GA 2CD2A 3QYLA 4M2XA 2W9GA 4TU5X 1KMVA 2O7PA 2FZIA 3FL9A 3NU0A 1RX5A 5JG0X 4KEBA 5U27A 1LY4A 1HFPA 3CSEA 1DRAA 3NXXA 1RF7A 3JWKA 2GD9A 1IA2A 3KFYA 1DYHA 3FRDX 3D84X 3NXRA 1JOLA 3K2HA 3JTWA 3GYFA 2XW7A 2AZNA 4KAKA 3FREX 3FS6A 4QJZD 2BLBA 3NTZA 4LAEX 4KJLA 2C2SA 3K47A 3TQ9A 1S3WA 4M6KA 4QLGA 3JWCA 3DL5A 3F91A 2FZJA 3FL8A 5HF0X 1E26A 4HOGA 4IXED 2LF1A 2B3ZA 4KJJA 3SRQX 5FDAA 5HQYA 5E8QA 3SQYX 1RH3A 2CIGA 4KBNA 2W3MA 3HBBA 2W9SA 3OAFA 1SEJA 5HT4A 3LG4A 1LUDA 1M78A 3KJSA 4H97A 1U71A 4XRBA 5ECXA 5CCCA 1BZFA 1PD9A 5HPBA 3N0HA 3IA4A 3K74A 3QLRA 4NX6A 3Q1HA 1DRBA 2QK8A 2W3WA 3NRRA 1PD8A 3DG8A 4KM2A 1RB3A 1DRHA 4P66A 1BOZA 5HF2X 4OSGA 3I3RA 3JWFA 3FQZA 3TQ8A 3CD2A 2BLAA 3SRSX 5HVEA 3FQOA 3F0VX 4GH8A 3GHCA 4M7VA 4ECKA 4ELHA 4G3MA 4RGCA 3QGTA 4LAGX 1RX1A 3NXVA 1VJ3A 4PSTA 1RD7A 4H95A 4G95A 4ELBA 3FQFA 3QYOA 5CC9A 6DFRA 3F0UX 3FRFX 3HJ3A 3KY8A 4M6JA 3DAUA 3DRCA 4KFJA 2H2QA 4XECX 3TQAA 4CD2A 1DRFA 3ZPGA 2FZHA 3IA5A 4Q67A 3GHVA 2INQA 2HQPA 3OCHA 1RX8A 4I13A 1MVSA 2G6VA 3TD8A 3NXOA 3JSUA 1JUVA 1S3UA 4P3QA 3QLSA 1DYRA 3FQ0A 3EEMA 2KGKA 1J3IA 4KLXA 1RB2A 3NZ6X 1S3VA 3CLBA 3IX9A 2W3VA 1RA2A 5HUIA 3QL3A 4H96A 1RX4A 4FGGA 4IXGX 4NX7A 1DAJA 1DR5A 1OHKA 3FRAX 1RA1A 4P68A 3SRRX 4PDJA 3QLWA 4DFRA 4I1NA 4OR7A 4DPHA 3FRBX 1CD2A 4LEKX 1U72A 4QLEA 3D80A 4XT6A 3NZDA 1IA3A 3NXYA 4DDRA 8DFRA 1M7AA 4KNEA 3FY9X 3IRMA 3SGYA 5EAJA 3DGAA 3FQCA 5DFRA 1RA9A 2OIPA 2ZZAA 4G8ZX 4KM0A 3ZPCA 5HQZA 4PTJA 3SA2A 1ZDRA 3L3RA 4H98A 1D1GA 1DG7A 1TDRA 4KY4A 3R33A 2L28A 4Q6AA 4HOEA 1CZ3A 1OHJA 3NZCX 4KD7A 3F0QX 4KJKA 1DHFA 3F0BX 1DHIA 4LAHX 4XT7A 1DF7A 4X5JA 1U70A 1RA3A 3UM5A 3QLYA 2HXVA 3JWMA 4HOFA 1DR2A 5HSRA 1DYJA 3KJRA 3ROAA 1RE7A 4QJCA 2W9TA 2JYBA 1M79A 3EX8A 3F8YA 1S3YA 2D0KA 1YHOA 5ECCA 2DHFA 3RO9A 3K45A 3SRUX 4FGHA 1MVTA 4X5IA 1IA4A 4M7UA 4DP3A 3DL6A 3F0XX 2W3AA 1RX9A 4X5GA 1DISA 1DG8A 1RG7A 3SH2A 3DATA 2BL9A 3JW5A 3RG9A 3SA1A 4Q0EA 3SRWX 1DR4A 5DXVA 3SAIA 3FYWX 3GI2A 3FY8X 4EIGA 3UM6A 3IRNA 4PSSA 1DR3A 1DHJA 2W3BA 4EILA 3DFRA 3S7AA 3NXTA 3QFXA 4HA9A 4PSYA 5HVBA 1RC4A 1DDSA 2OBCA 1AOEA 4DPDA 4XT5A 2W9HA 1AO8A 4P3RA 1IA1A 3FQVA 4Q0DA 3EEJA 4QLFA 4IXFX 1KMSA 1DG5A 1DIUA 2ANOA 3NZBX 3S3VA 3EIGA 4KY8A 4XT4A 3NZAX 2ITHA 1RA8A 1RX7A 2DRCA 3NZ9X 3CL9A 5JA3A 1DDRA 5HSUA 1DYIA 1J3KA 2D5NA 1RX3A 1JOMA 1HFRA 4ELEA 3QL0A 1DR6A 4FHBA 1VDRA 5U26A 1DLSA 4X5FA 1DR7A 3I8AX 4HA7A 7DFRA 1DLRA 4KL9A 4X5HA 1AI9A 3GHWA 3JW3A 3IROA 4M6LA 1KLKA 4QI9A 3INVA 3FYVX 4ELFA 5HI6A 1QZFA 3EELA 4EJ1A 2ANQA 3KGYA 3E0BA
chains in the Genus database with same CATH superfamily
4QHVA 3SR5X 3QLZA 1LY3A 3F0SX 5HT5A 2C2TA 1RX6A 3QLXA 4PTHA 4XT8A 1DREA 3S9UA 4ELGA 3JVXA 4KYAA 1RX2A 1HFQA 3M09A 4EIZA 3UM8A 4XE6X 1DR1A 3VCOA 3M08A 3EEKA 3QG2A 2BLCA 1PDBA 3F8ZA 3TQBA 2HM9A 1J3JA 2P4GA 2CD2A 3QYLA 4M2XA 2W9GA 4TU5X 1KMVA 2O7PA 2FZIA 3FL9A 3NU0A 1RX5A 5JG0X 4KEBA 5U27A 1LY4A 1HFPA 3CSEA 1DRAA 3NXXA 1RF7A 3JWKA 2GD9A 1IA2A 3KFYA 1DYHA 3FRDX 3D84X 3NXRA 1JOLA 3K2HA 3JTWA 3GYFA 2XW7A 2AZNA 4KAKA 3FREX 3FS6A 4QJZD 2BLBA 3NTZA 4LAEX 4KJLA 2C2SA 3K47A 3TQ9A 1S3WA 4M6KA 4QLGA 3JWCA 3DL5A 3F91A 2FZJA 3FL8A 5HF0X 1E26A 4HOGA 4IXED 2LF1A 2B3ZA 4KJJA 3SRQX 5FDAA 5HQYA 5E8QA 3SQYX 1RH3A 2CIGA 4KBNA 2W3MA 3HBBA 2W9SA 3OAFA 1SEJA 5HT4A 3LG4A 1LUDA 1M78A 3KJSA 4H97A 1U71A 4XRBA 5ECXA 5CCCA 1BZFA 1PD9A 5HPBA 3N0HA 3IA4A 3K74A 3QLRA 4NX6A 3Q1HA 1DRBA 2QK8A 2W3WA 3NRRA 1PD8A 3DG8A 4KM2A 1RB3A 1DRHA 4P66A 1BOZA 5HF2X 4OSGA 3I3RA 3JWFA 3FQZA 3TQ8A 3CD2A 2BLAA 3SRSX 5HVEA 3FQOA 3F0VX 4GH8A 3GHCA 4M7VA 4ECKA 4ELHA 4G3MA 4RGCA 3QGTA 4LAGX 1RX1A 3NXVA 1VJ3A 4PSTA 1RD7A 4H95A 4G95A 4ELBA 3FQFA 3QYOA 5CC9A 6DFRA 3F0UX 3FRFX 3HJ3A 3KY8A 4M6JA 3DAUA 3DRCA 4KFJA 2H2QA 4XECX 3TQAA 4CD2A 1DRFA 3ZPGA 2FZHA 3IA5A 4Q67A 3GHVA 2INQA 2HQPA 3OCHA 1RX8A 4I13A 1MVSA 2G6VA 3TD8A 3NXOA 3JSUA 1JUVA 1S3UA 4P3QA 3QLSA 1DYRA 3FQ0A 3EEMA 2KGKA 1J3IA 4KLXA 1RB2A 3NZ6X 1S3VA 3CLBA 3IX9A 2W3VA 1RA2A 5HUIA 3QL3A 4H96A 1RX4A 4FGGA 4IXGX 4NX7A 1DAJA 1DR5A 1OHKA 3FRAX 1RA1A 4P68A 3SRRX 4PDJA 3QLWA 4DFRA 4I1NA 4OR7A 4DPHA 3FRBX 1CD2A 4LEKX 1U72A 4QLEA 3D80A 4XT6A 3NZDA 1IA3A 3NXYA 4DDRA 8DFRA 1M7AA 4KNEA 3FY9X 3IRMA 3SGYA 5EAJA 3DGAA 3FQCA 5DFRA 1RA9A 2OIPA 2ZZAA 4G8ZX 4KM0A 3ZPCA 5HQZA 4PTJA 3SA2A 1ZDRA 3L3RA 4H98A 1D1GA 1DG7A 1TDRA 4KY4A 3R33A 2L28A 4Q6AA 4HOEA 1CZ3A 1OHJA 3NZCX 4KD7A 3F0QX 4KJKA 1DHFA 3F0BX 1DHIA 4LAHX 4XT7A 1DF7A 4X5JA 1U70A 1RA3A 3UM5A 3QLYA 2HXVA 3JWMA 4HOFA 1DR2A 5HSRA 1DYJA 3KJRA 3ROAA 1RE7A 4QJCA 2W9TA 2JYBA 1M79A 3EX8A 3F8YA 1S3YA 2D0KA 1YHOA 5ECCA 2DHFA 3RO9A 3K45A 3SRUX 4FGHA 1MVTA 4X5IA 1IA4A 4M7UA 4DP3A 3DL6A 3F0XX 2W3AA 1RX9A 4X5GA 1DISA 1DG8A 1RG7A 3SH2A 3DATA 2BL9A 3JW5A 3RG9A 3SA1A 4Q0EA 3SRWX 1DR4A 5DXVA 3SAIA 3FYWX 3GI2A 3FY8X 4EIGA 3UM6A 3IRNA 4PSSA 1DR3A 1DHJA 2W3BA 4EILA 3DFRA 3S7AA 3NXTA 3QFXA 4HA9A 4PSYA 5HVBA 1RC4A 1DDSA 2OBCA 1AOEA 4DPDA 4XT5A 2W9HA 1AO8A 4P3RA 1IA1A 3FQVA 4Q0DA 3EEJA 4QLFA 4IXFX 1KMSA 1DG5A 1DIUA 2ANOA 3NZBX 3S3VA 3EIGA 4KY8A 4XT4A 3NZAX 2ITHA 1RA8A 1RX7A 2DRCA 3NZ9X 3CL9A 5JA3A 1DDRA 5HSUA 1DYIA 1J3KA 2D5NA 1RX3A 1JOMA 1HFRA 4ELEA 3QL0A 1DR6A 4FHBA 1VDRA 5U26A 1DLSA 4X5FA 1DR7A 3I8AX 4HA7A 7DFRA 1DLRA 4KL9A 4X5HA 1AI9A 3GHWA 3JW3A 3IROA 4M6LA 1KLKA 4QI9A 3INVA 3FYVX 4ELFA 5HI6A 1QZFA 3EELA 4EJ1A 2ANQA 3KGYA 3E0BA
chains in the Genus database with same CATH topology
4QHVA 3SR5X 3QLZA 1LY3A 3F0SX 5HT5A 2C2TA 1RX6A 3QLXA 4PTHA 4XT8A 1DREA 3S9UA 4ELGA 3JVXA 4KYAA 1RX2A 1HFQA 3M09A 4EIZA 3UM8A 4XE6X 1DR1A 3VCOA 3M08A 3EEKA 3QG2A 2BLCA 1PDBA 3F8ZA 3TQBA 2HM9A 1J3JA 2P4GA 2CD2A 3QYLA 4M2XA 2W9GA 4TU5X 1KMVA 2O7PA 2FZIA 3FL9A 3NU0A 1RX5A 5JG0X 4KEBA 5U27A 1LY4A 1HFPA 3CSEA 1DRAA 3NXXA 1RF7A 3JWKA 2GD9A 1IA2A 3KFYA 1DYHA 3FRDX 3D84X 3NXRA 1JOLA 3K2HA 3JTWA 3GYFA 2XW7A 2AZNA 4KAKA 3FREX 3FS6A 4QJZD 2BLBA 3NTZA 4LAEX 4KJLA 2C2SA 3K47A 3TQ9A 1S3WA 4M6KA 4QLGA 3JWCA 3DL5A 3F91A 2FZJA 3FL8A 5HF0X 1E26A 4HOGA 4IXED 2LF1A 2B3ZA 4KJJA 3SRQX 5FDAA 5HQYA 5E8QA 3SQYX 1RH3A 2CIGA 4KBNA 2W3MA 3HBBA 2W9SA 3OAFA 1SEJA 5HT4A 3LG4A 1LUDA 1M78A 3KJSA 4H97A 1U71A 4XRBA 5ECXA 5CCCA 1BZFA 1PD9A 5HPBA 3N0HA 3IA4A 3K74A 3QLRA 4NX6A 3Q1HA 1DRBA 2QK8A 2W3WA 3NRRA 1PD8A 3DG8A 4KM2A 1RB3A 1DRHA 4P66A 1BOZA 5HF2X 4OSGA 3I3RA 3JWFA 3FQZA 3TQ8A 3CD2A 2BLAA 3SRSX 5HVEA 3FQOA 3F0VX 4GH8A 3GHCA 4M7VA 4ECKA 4ELHA 4G3MA 4RGCA 3QGTA 4LAGX 1RX1A 3NXVA 1VJ3A 4PSTA 1RD7A 4H95A 4G95A 4ELBA 3FQFA 3QYOA 5CC9A 6DFRA 3F0UX 3FRFX 3HJ3A 3KY8A 4M6JA 3DAUA 3DRCA 4KFJA 2H2QA 4XECX 3TQAA 4CD2A 1DRFA 3ZPGA 2FZHA 3IA5A 4Q67A 3GHVA 2INQA 2HQPA 3OCHA 1RX8A 4I13A 1MVSA 2G6VA 3TD8A 3NXOA 3JSUA 1JUVA 1S3UA 4P3QA 3QLSA 1DYRA 3FQ0A 3EEMA 2KGKA 1J3IA 4KLXA 1RB2A 3NZ6X 1S3VA 3CLBA 3IX9A 2W3VA 1RA2A 5HUIA 3QL3A 4H96A 1RX4A 4FGGA 4IXGX 4NX7A 1DAJA 1DR5A 1OHKA 3FRAX 1RA1A 4P68A 3SRRX 4PDJA 3QLWA 4DFRA 4I1NA 4OR7A 4DPHA 3FRBX 1CD2A 4LEKX 1U72A 4QLEA 3D80A 4XT6A 3NZDA 1IA3A 3NXYA 4DDRA 8DFRA 1M7AA 4KNEA 3FY9X 3IRMA 3SGYA 5EAJA 3DGAA 3FQCA 5DFRA 1RA9A 2OIPA 2ZZAA 4G8ZX 4KM0A 3ZPCA 5HQZA 4PTJA 3SA2A 1ZDRA 3L3RA 4H98A 1D1GA 1DG7A 1TDRA 4KY4A 3R33A 2L28A 4Q6AA 4HOEA 1CZ3A 1OHJA 3NZCX 4KD7A 3F0QX 4KJKA 1DHFA 3F0BX 1DHIA 4LAHX 4XT7A 1DF7A 4X5JA 1U70A 1RA3A 3UM5A 3QLYA 2HXVA 3JWMA 4HOFA 1DR2A 5HSRA 1DYJA 3KJRA 3ROAA 1RE7A 4QJCA 2W9TA 2JYBA 1M79A 3EX8A 3F8YA 1S3YA 2D0KA 1YHOA 5ECCA 2DHFA 3RO9A 3K45A 3SRUX 4FGHA 1MVTA 4X5IA 1IA4A 4M7UA 4DP3A 3DL6A 3F0XX 2W3AA 1RX9A 4X5GA 1DISA 1DG8A 1RG7A 3SH2A 3DATA 2BL9A 3JW5A 3RG9A 3SA1A 4Q0EA 3SRWX 1DR4A 5DXVA 3SAIA 3FYWX 3GI2A 3FY8X 4EIGA 3UM6A 3IRNA 4PSSA 1DR3A 1DHJA 2W3BA 4EILA 3DFRA 3S7AA 3NXTA 3QFXA 4HA9A 4PSYA 5HVBA 1RC4A 1DDSA 2OBCA 1AOEA 4DPDA 4XT5A 2W9HA 1AO8A 4P3RA 1IA1A 3FQVA 4Q0DA 3EEJA 4QLFA 4IXFX 1KMSA 1DG5A 1DIUA 2ANOA 3NZBX 3S3VA 3EIGA 4KY8A 4XT4A 3NZAX 2ITHA 1RA8A 1RX7A 2DRCA 3NZ9X 3CL9A 5JA3A 1DDRA 5HSUA 1DYIA 1J3KA 2D5NA 1RX3A 1JOMA 1HFRA 4ELEA 3QL0A 1DR6A 4FHBA 1VDRA 5U26A 1DLSA 4X5FA 1DR7A 3I8AX 4HA7A 7DFRA 1DLRA 4KL9A 4X5HA 1AI9A 3GHWA 3JW3A 3IROA 4M6LA 1KLKA 4QI9A 3INVA 3FYVX 4ELFA 5HI6A 1QZFA 3EELA 4EJ1A 2ANQA 3KGYA 3E0BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QHV A;  3SR5 X;  3QLZ A;  1LY3 A;  3F0S X;  5HT5 A;  2C2T A;  1RX6 A;  3QLX A;  4PTH A;  4XT8 A;  1DRE A;  3S9U A;  4ELG A;  3JVX A;  4KYA A;  1RX2 A;  1HFQ A;  3M09 A;  4EIZ A;  3UM8 A;  4XE6 X;  1DR1 A;  3VCO A;  3M08 A;  3EEK A;  3QG2 A;  2BLC A;  1PDB A;  3F8Z A;  3TQB A;  2HM9 A;  1J3J A;  2P4G A;  2CD2 A;  3QYL A;  4M2X A;  2W9G A;  4TU5 X;  1KMV A;  2O7P A;  2FZI A;  3FL9 A;  3NU0 A;  1RX5 A;  5JG0 X;  4KEB A;  5U27 A;  1LY4 A;  1HFP A;  3CSE A;  1DRA A;  3NXX A;  1RF7 A;  3JWK A;  2GD9 A;  1IA2 A;  3KFY A;  1DYH A;  3FRD X;  3D84 X;  3NXR A;  1JOL A;  3K2H A;  3JTW A;  3GYF A;  2XW7 A;  2AZN A;  4KAK A;  3FRE X;  3FS6 A;  4QJZ D;  2BLB A;  3NTZ A;  4LAE X;  4KJL A;  2C2S A;  3K47 A;  3TQ9 A;  1S3W A;  4M6K A;  4QLG A;  3JWC A;  3DL5 A;  3F91 A;  2FZJ A;  3FL8 A;  5HF0 X;  1E26 A;  4HOG A;  4IXE D;  2LF1 A;  2B3Z A;  4KJJ A;  3SRQ X;  5FDA A;  5HQY A;  5E8Q A;  3SQY X;  1RH3 A;  2CIG A;  4KBN A;  2W3M A;  3HBB A;  2W9S A;  3OAF A;  1SEJ A;  5HT4 A;  3LG4 A;  1LUD A;  1M78 A;  3KJS A;  4H97 A;  1U71 A;  4XRB A;  5ECX A;  5CCC A;  1BZF A;  1PD9 A;  5HPB A;  3N0H A;  3IA4 A;  3K74 A;  3QLR A;  4NX6 A;  3Q1H A;  1DRB A;  2QK8 A;  2W3W A;  3NRR A;  1PD8 A;  3DG8 A;  4KM2 A;  1RB3 A;  1DRH A;  4P66 A;  1BOZ A;  5HF2 X;  4OSG A;  3I3R A;  3JWF A;  3FQZ A;  3TQ8 A;  3CD2 A;  2BLA A;  3SRS X;  5HVE A;  3FQO A;  3F0V X;  4GH8 A;  3GHC A;  4M7V A;  4ECK A;  4ELH A;  4G3M A;  4RGC A;  3QGT A;  4LAG X;  1RX1 A;  3NXV A;  1VJ3 A;  4PST A;  1RD7 A;  4H95 A;  4G95 A;  4ELB A;  3FQF A;  3QYO A;  5CC9 A;  6DFR A;  3F0U X;  3FRF X;  3HJ3 A;  3KY8 A;  4M6J A;  3DAU A;  3DRC A;  4KFJ A;  2H2Q A;  4XEC X;  3TQA A;  4CD2 A;  1DRF A;  3ZPG A;  2FZH A;  3IA5 A;  4Q67 A;  3GHV A;  2INQ A;  2HQP A;  3OCH A;  1RX8 A;  4I13 A;  1MVS A;  2G6V A;  3TD8 A;  3NXO A;  3JSU A;  1JUV A;  1S3U A;  4P3Q A;  3QLS A;  1DYR A;  3FQ0 A;  3EEM A;  2KGK A;  1J3I A;  4KLX A;  1RB2 A;  3NZ6 X;  1S3V A;  3CLB A;  3IX9 A;  2W3V A;  1RA2 A;  5HUI A;  3QL3 A;  4H96 A;  1RX4 A;  4FGG A;  4IXG X;  4NX7 A;  1DAJ A;  1DR5 A;  1OHK A;  3FRA X;  1RA1 A;  4P68 A;  3SRR X;  4PDJ A;  3QLW A;  4DFR A;  4I1N A;  4OR7 A;  4DPH A;  3FRB X;  1CD2 A;  4LEK X;  1U72 A;  4QLE A;  3D80 A;  4XT6 A;  3NZD A;  1IA3 A;  3NXY A;  4DDR A;  8DFR A;  1M7A A;  4KNE A;  3FY9 X;  3IRM A;  3SGY A;  5EAJ A;  3DGA A;  3FQC A;  5DFR A;  1RA9 A;  2OIP A;  2ZZA A;  4G8Z X;  4KM0 A;  3ZPC A;  5HQZ A;  4PTJ A;  3SA2 A;  1ZDR A;  3L3R A;  4H98 A;  1D1G A;  1DG7 A;  1TDR A;  4KY4 A;  3R33 A;  2L28 A;  4Q6A A;  4HOE A;  1CZ3 A;  1OHJ A;  3NZC X;  4KD7 A;  3F0Q X;  4KJK A;  1DHF A;  3F0B X;  1DHI A;  4LAH X;  4XT7 A;  1DF7 A;  4X5J A;  1U70 A;  1RA3 A;  3UM5 A;  3QLY A;  2HXV A;  3JWM A;  4HOF A;  1DR2 A;  5HSR A;  1DYJ A;  3KJR A;  3ROA A;  1RE7 A;  4QJC A;  2W9T A;  2JYB A;  1M79 A;  3EX8 A;  3F8Y A;  1S3Y A;  2D0K A;  1YHO A;  5ECC A;  2DHF A;  3RO9 A;  3K45 A;  3SRU X;  4FGH A;  1MVT A;  4X5I A;  1IA4 A;  4M7U A;  4DP3 A;  3DL6 A;  3F0X X;  2W3A A;  1RX9 A;  4X5G A;  1DIS A;  1DG8 A;  1RG7 A;  3SH2 A;  3DAT A;  2BL9 A;  3JW5 A;  3RG9 A;  3SA1 A;  4Q0E A;  3SRW X;  1DR4 A;  5DXV A;  3SAI A;  3FYW X;  3GI2 A;  3FY8 X;  4EIG A;  3UM6 A;  3IRN A;  4PSS A;  1DR3 A;  1DHJ A;  2W3B A;  4EIL A;  3DFR A;  3S7A A;  3NXT A;  3QFX A;  4HA9 A;  4PSY A;  5HVB A;  1RC4 A;  1DDS A;  2OBC A;  1AOE A;  4DPD A;  4XT5 A;  2W9H A;  1AO8 A;  4P3R A;  1IA1 A;  3FQV A;  4Q0D A;  3EEJ A;  4QLF A;  4IXF X;  1KMS A;  1DG5 A;  1DIU A;  2ANO A;  3NZB X;  3S3V A;  3EIG A;  4KY8 A;  4XT4 A;  3NZA X;  2ITH A;  1RA8 A;  1RX7 A;  2DRC A;  3NZ9 X;  3CL9 A;  5JA3 A;  1DDR A;  5HSU A;  1DYI A;  1J3K A;  2D5N A;  1RX3 A;  1JOM A;  1HFR A;  4ELE A;  3QL0 A;  1DR6 A;  4FHB A;  1VDR A;  5U26 A;  1DLS A;  4X5F A;  1DR7 A;  3I8A X;  4HA7 A;  7DFR A;  1DLR A;  4KL9 A;  4X5H A;  1AI9 A;  3GHW A;  3JW3 A;  3IRO A;  4M6L A;  1KLK A;  4QI9 A;  3INV A;  3FYV X;  4ELF A;  5HI6 A;  1QZF A;  3EEL A;  4EJ1 A;  2ANQ A;  3KGY A;  3E0B A; 
#chains in the Genus database with same CATH topology
 4QHV A;  3SR5 X;  3QLZ A;  1LY3 A;  3F0S X;  5HT5 A;  2C2T A;  1RX6 A;  3QLX A;  4PTH A;  4XT8 A;  1DRE A;  3S9U A;  4ELG A;  3JVX A;  4KYA A;  1RX2 A;  1HFQ A;  3M09 A;  4EIZ A;  3UM8 A;  4XE6 X;  1DR1 A;  3VCO A;  3M08 A;  3EEK A;  3QG2 A;  2BLC A;  1PDB A;  3F8Z A;  3TQB A;  2HM9 A;  1J3J A;  2P4G A;  2CD2 A;  3QYL A;  4M2X A;  2W9G A;  4TU5 X;  1KMV A;  2O7P A;  2FZI A;  3FL9 A;  3NU0 A;  1RX5 A;  5JG0 X;  4KEB A;  5U27 A;  1LY4 A;  1HFP A;  3CSE A;  1DRA A;  3NXX A;  1RF7 A;  3JWK A;  2GD9 A;  1IA2 A;  3KFY A;  1DYH A;  3FRD X;  3D84 X;  3NXR A;  1JOL A;  3K2H A;  3JTW A;  3GYF A;  2XW7 A;  2AZN A;  4KAK A;  3FRE X;  3FS6 A;  4QJZ D;  2BLB A;  3NTZ A;  4LAE X;  4KJL A;  2C2S A;  3K47 A;  3TQ9 A;  1S3W A;  4M6K A;  4QLG A;  3JWC A;  3DL5 A;  3F91 A;  2FZJ A;  3FL8 A;  5HF0 X;  1E26 A;  4HOG A;  4IXE D;  2LF1 A;  2B3Z A;  4KJJ A;  3SRQ X;  5FDA A;  5HQY A;  5E8Q A;  3SQY X;  1RH3 A;  2CIG A;  4KBN A;  2W3M A;  3HBB A;  2W9S A;  3OAF A;  1SEJ A;  5HT4 A;  3LG4 A;  1LUD A;  1M78 A;  3KJS A;  4H97 A;  1U71 A;  4XRB A;  5ECX A;  5CCC A;  1BZF A;  1PD9 A;  5HPB A;  3N0H A;  3IA4 A;  3K74 A;  3QLR A;  4NX6 A;  3Q1H A;  1DRB A;  2QK8 A;  2W3W A;  3NRR A;  1PD8 A;  3DG8 A;  4KM2 A;  1RB3 A;  1DRH A;  4P66 A;  1BOZ A;  5HF2 X;  4OSG A;  3I3R A;  3JWF A;  3FQZ A;  3TQ8 A;  3CD2 A;  2BLA A;  3SRS X;  5HVE A;  3FQO A;  3F0V X;  4GH8 A;  3GHC A;  4M7V A;  4ECK A;  4ELH A;  4G3M A;  4RGC A;  3QGT A;  4LAG X;  1RX1 A;  3NXV A;  1VJ3 A;  4PST A;  1RD7 A;  4H95 A;  4G95 A;  4ELB A;  3FQF A;  3QYO A;  5CC9 A;  6DFR A;  3F0U X;  3FRF X;  3HJ3 A;  3KY8 A;  4M6J A;  3DAU A;  3DRC A;  4KFJ A;  2H2Q A;  4XEC X;  3TQA A;  4CD2 A;  1DRF A;  3ZPG A;  2FZH A;  3IA5 A;  4Q67 A;  3GHV A;  2INQ A;  2HQP A;  3OCH A;  1RX8 A;  4I13 A;  1MVS A;  2G6V A;  3TD8 A;  3NXO A;  3JSU A;  1JUV A;  1S3U A;  4P3Q A;  3QLS A;  1DYR A;  3FQ0 A;  3EEM A;  2KGK A;  1J3I A;  4KLX A;  1RB2 A;  3NZ6 X;  1S3V A;  3CLB A;  3IX9 A;  2W3V A;  1RA2 A;  5HUI A;  3QL3 A;  4H96 A;  1RX4 A;  4FGG A;  4IXG X;  4NX7 A;  1DAJ A;  1DR5 A;  1OHK A;  3FRA X;  1RA1 A;  4P68 A;  3SRR X;  4PDJ A;  3QLW A;  4DFR A;  4I1N A;  4OR7 A;  4DPH A;  3FRB X;  1CD2 A;  4LEK X;  1U72 A;  4QLE A;  3D80 A;  4XT6 A;  3NZD A;  1IA3 A;  3NXY A;  4DDR A;  8DFR A;  1M7A A;  4KNE A;  3FY9 X;  3IRM A;  3SGY A;  5EAJ A;  3DGA A;  3FQC A;  5DFR A;  1RA9 A;  2OIP A;  2ZZA A;  4G8Z X;  4KM0 A;  3ZPC A;  5HQZ A;  4PTJ A;  3SA2 A;  1ZDR A;  3L3R A;  4H98 A;  1D1G A;  1DG7 A;  1TDR A;  4KY4 A;  3R33 A;  2L28 A;  4Q6A A;  4HOE A;  1CZ3 A;  1OHJ A;  3NZC X;  4KD7 A;  3F0Q X;  4KJK A;  1DHF A;  3F0B X;  1DHI A;  4LAH X;  4XT7 A;  1DF7 A;  4X5J A;  1U70 A;  1RA3 A;  3UM5 A;  3QLY A;  2HXV A;  3JWM A;  4HOF A;  1DR2 A;  5HSR A;  1DYJ A;  3KJR A;  3ROA A;  1RE7 A;  4QJC A;  2W9T A;  2JYB A;  1M79 A;  3EX8 A;  3F8Y A;  1S3Y A;  2D0K A;  1YHO A;  5ECC A;  2DHF A;  3RO9 A;  3K45 A;  3SRU X;  4FGH A;  1MVT A;  4X5I A;  1IA4 A;  4M7U A;  4DP3 A;  3DL6 A;  3F0X X;  2W3A A;  1RX9 A;  4X5G A;  1DIS A;  1DG8 A;  1RG7 A;  3SH2 A;  3DAT A;  2BL9 A;  3JW5 A;  3RG9 A;  3SA1 A;  4Q0E A;  3SRW X;  1DR4 A;  5DXV A;  3SAI A;  3FYW X;  3GI2 A;  3FY8 X;  4EIG A;  3UM6 A;  3IRN A;  4PSS A;  1DR3 A;  1DHJ A;  2W3B A;  4EIL A;  3DFR A;  3S7A A;  3NXT A;  3QFX A;  4HA9 A;  4PSY A;  5HVB A;  1RC4 A;  1DDS A;  2OBC A;  1AOE A;  4DPD A;  4XT5 A;  2W9H A;  1AO8 A;  4P3R A;  1IA1 A;  3FQV A;  4Q0D A;  3EEJ A;  4QLF A;  4IXF X;  1KMS A;  1DG5 A;  1DIU A;  2ANO A;  3NZB X;  3S3V A;  3EIG A;  4KY8 A;  4XT4 A;  3NZA X;  2ITH A;  1RA8 A;  1RX7 A;  2DRC A;  3NZ9 X;  3CL9 A;  5JA3 A;  1DDR A;  5HSU A;  1DYI A;  1J3K A;  2D5N A;  1RX3 A;  1JOM A;  1HFR A;  4ELE A;  3QL0 A;  1DR6 A;  4FHB A;  1VDR A;  5U26 A;  1DLS A;  4X5F A;  1DR7 A;  3I8A X;  4HA7 A;  7DFR A;  1DLR A;  4KL9 A;  4X5H A;  1AI9 A;  3GHW A;  3JW3 A;  3IRO A;  4M6L A;  1KLK A;  4QI9 A;  3INV A;  3FYV X;  4ELF A;  5HI6 A;  1QZF A;  3EEL A;  4EJ1 A;  2ANQ A;  3KGY A;  3E0B A; 
#chains in the Genus database with same CATH homology
 4QHV A;  3SR5 X;  3QLZ A;  1LY3 A;  3F0S X;  5HT5 A;  2C2T A;  1RX6 A;  3QLX A;  4PTH A;  4XT8 A;  1DRE A;  3S9U A;  4ELG A;  3JVX A;  4KYA A;  1RX2 A;  1HFQ A;  3M09 A;  4EIZ A;  3UM8 A;  4XE6 X;  1DR1 A;  3VCO A;  3M08 A;  3EEK A;  3QG2 A;  2BLC A;  1PDB A;  3F8Z A;  3TQB A;  2HM9 A;  1J3J A;  2P4G A;  2CD2 A;  3QYL A;  4M2X A;  2W9G A;  4TU5 X;  1KMV A;  2O7P A;  2FZI A;  3FL9 A;  3NU0 A;  1RX5 A;  5JG0 X;  4KEB A;  5U27 A;  1LY4 A;  1HFP A;  3CSE A;  1DRA A;  3NXX A;  1RF7 A;  3JWK A;  2GD9 A;  1IA2 A;  3KFY A;  1DYH A;  3FRD X;  3D84 X;  3NXR A;  1JOL A;  3K2H A;  3JTW A;  3GYF A;  2XW7 A;  2AZN A;  4KAK A;  3FRE X;  3FS6 A;  4QJZ D;  2BLB A;  3NTZ A;  4LAE X;  4KJL A;  2C2S A;  3K47 A;  3TQ9 A;  1S3W A;  4M6K A;  4QLG A;  3JWC A;  3DL5 A;  3F91 A;  2FZJ A;  3FL8 A;  5HF0 X;  1E26 A;  4HOG A;  4IXE D;  2LF1 A;  2B3Z A;  4KJJ A;  3SRQ X;  5FDA A;  5HQY A;  5E8Q A;  3SQY X;  1RH3 A;  2CIG A;  4KBN A;  2W3M A;  3HBB A;  2W9S A;  3OAF A;  1SEJ A;  5HT4 A;  3LG4 A;  1LUD A;  1M78 A;  3KJS A;  4H97 A;  1U71 A;  4XRB A;  5ECX A;  5CCC A;  1BZF A;  1PD9 A;  5HPB A;  3N0H A;  3IA4 A;  3K74 A;  3QLR A;  4NX6 A;  3Q1H A;  1DRB A;  2QK8 A;  2W3W A;  3NRR A;  1PD8 A;  3DG8 A;  4KM2 A;  1RB3 A;  1DRH A;  4P66 A;  1BOZ A;  5HF2 X;  4OSG A;  3I3R A;  3JWF A;  3FQZ A;  3TQ8 A;  3CD2 A;  2BLA A;  3SRS X;  5HVE A;  3FQO A;  3F0V X;  4GH8 A;  3GHC A;  4M7V A;  4ECK A;  4ELH A;  4G3M A;  4RGC A;  3QGT A;  4LAG X;  1RX1 A;  3NXV A;  1VJ3 A;  4PST A;  1RD7 A;  4H95 A;  4G95 A;  4ELB A;  3FQF A;  3QYO A;  5CC9 A;  6DFR A;  3F0U X;  3FRF X;  3HJ3 A;  3KY8 A;  4M6J A;  3DAU A;  3DRC A;  4KFJ A;  2H2Q A;  4XEC X;  3TQA A;  4CD2 A;  1DRF A;  3ZPG A;  2FZH A;  3IA5 A;  4Q67 A;  3GHV A;  2INQ A;  2HQP A;  3OCH A;  1RX8 A;  4I13 A;  1MVS A;  2G6V A;  3TD8 A;  3NXO A;  3JSU A;  1JUV A;  1S3U A;  4P3Q A;  3QLS A;  1DYR A;  3FQ0 A;  3EEM A;  2KGK A;  1J3I A;  4KLX A;  1RB2 A;  3NZ6 X;  1S3V A;  3CLB A;  3IX9 A;  2W3V A;  1RA2 A;  5HUI A;  3QL3 A;  4H96 A;  1RX4 A;  4FGG A;  4IXG X;  4NX7 A;  1DAJ A;  1DR5 A;  1OHK A;  3FRA X;  1RA1 A;  4P68 A;  3SRR X;  4PDJ A;  3QLW A;  4DFR A;  4I1N A;  4OR7 A;  4DPH A;  3FRB X;  1CD2 A;  4LEK X;  1U72 A;  4QLE A;  3D80 A;  4XT6 A;  3NZD A;  1IA3 A;  3NXY A;  4DDR A;  8DFR A;  1M7A A;  4KNE A;  3FY9 X;  3IRM A;  3SGY A;  5EAJ A;  3DGA A;  3FQC A;  5DFR A;  1RA9 A;  2OIP A;  2ZZA A;  4G8Z X;  4KM0 A;  3ZPC A;  5HQZ A;  4PTJ A;  3SA2 A;  1ZDR A;  3L3R A;  4H98 A;  1D1G A;  1DG7 A;  1TDR A;  4KY4 A;  3R33 A;  2L28 A;  4Q6A A;  4HOE A;  1CZ3 A;  1OHJ A;  3NZC X;  4KD7 A;  3F0Q X;  4KJK A;  1DHF A;  3F0B X;  1DHI A;  4LAH X;  4XT7 A;  1DF7 A;  4X5J A;  1U70 A;  1RA3 A;  3UM5 A;  3QLY A;  2HXV A;  3JWM A;  4HOF A;  1DR2 A;  5HSR A;  1DYJ A;  3KJR A;  3ROA A;  1RE7 A;  4QJC A;  2W9T A;  2JYB A;  1M79 A;  3EX8 A;  3F8Y A;  1S3Y A;  2D0K A;  1YHO A;  5ECC A;  2DHF A;  3RO9 A;  3K45 A;  3SRU X;  4FGH A;  1MVT A;  4X5I A;  1IA4 A;  4M7U A;  4DP3 A;  3DL6 A;  3F0X X;  2W3A A;  1RX9 A;  4X5G A;  1DIS A;  1DG8 A;  1RG7 A;  3SH2 A;  3DAT A;  2BL9 A;  3JW5 A;  3RG9 A;  3SA1 A;  4Q0E A;  3SRW X;  1DR4 A;  5DXV A;  3SAI A;  3FYW X;  3GI2 A;  3FY8 X;  4EIG A;  3UM6 A;  3IRN A;  4PSS A;  1DR3 A;  1DHJ A;  2W3B A;  4EIL A;  3DFR A;  3S7A A;  3NXT A;  3QFX A;  4HA9 A;  4PSY A;  5HVB A;  1RC4 A;  1DDS A;  2OBC A;  1AOE A;  4DPD A;  4XT5 A;  2W9H A;  1AO8 A;  4P3R A;  1IA1 A;  3FQV A;  4Q0D A;  3EEJ A;  4QLF A;  4IXF X;  1KMS A;  1DG5 A;  1DIU A;  2ANO A;  3NZB X;  3S3V A;  3EIG A;  4KY8 A;  4XT4 A;  3NZA X;  2ITH A;  1RA8 A;  1RX7 A;  2DRC A;  3NZ9 X;  3CL9 A;  5JA3 A;  1DDR A;  5HSU A;  1DYI A;  1J3K A;  2D5N A;  1RX3 A;  1JOM A;  1HFR A;  4ELE A;  3QL0 A;  1DR6 A;  4FHB A;  1VDR A;  5U26 A;  1DLS A;  4X5F A;  1DR7 A;  3I8A X;  4HA7 A;  7DFR A;  1DLR A;  4KL9 A;  4X5H A;  1AI9 A;  3GHW A;  3JW3 A;  3IRO A;  4M6L A;  1KLK A;  4QI9 A;  3INV A;  3FYV X;  4ELF A;  5HI6 A;  1QZF A;  3EEL A;  4EJ1 A;  2ANQ A;  3KGY A;  3E0B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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