1DF7A

Dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and methotrexate
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
159
structure length
159
Chain Sequence
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 38
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1999-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1df7A00
5HUIA 4ECKA 5E8QA 4M7UA 4X5IA 2AZNA 3QLZA 1DG8A 1RX1A 2FZHA 1RA1A 3EELA 5HQZA 3K74A 4P3QA 3TQ8A 3KY8A 4PSYA 3JWKA 1DLRA 1DR5A 4QI9A 4IXFX 3SQYX 4HOEA 4DFRA 1PD9A 4ELGA 3K45A 2INQA 4FGHA 4Q67A 1VJ3A 3JWCA 3GHVA 5JG0X 5JA3A 4HOFA 3M08A 2H2QA 3QL0A 4Q6AA 5U26A 3DFRA 1RD7A 4FHBA 2BLAA 1DR2A 1E26A 4QHVA 5FDAA 1DLSA 3F0QX 3M09A 3FL9A 4PSTA 4GH8A 3DATA 1JOLA 2W9SA 3LG4A 4LAGX 4M6KA 2CIGA 3I3RA 1AOEA 2DRCA 1DHIA 5EAJA 4KNEA 4X5GA 3TQAA 4ELFA 3I8AX 2ANQA 4KBNA 3CD2A 4DPHA 1MVSA 3NXVA 3EEKA 1BZFA 3NXTA 1RC4A 4XT5A 4IXGX 4M2XA 3Q1HA 4PDJA 1S3WA 3DRCA 3DL5A 5CCCA 4NX6A 3QLSA 3NTZA 3S3VA 1S3UA 3FRAX 3F8YA 4DDRA 5U27A 4OSGA 1RB2A 4LAEX 2DHFA 2W3MA 5DFRA 3FRFX 1HFRA 3IA4A 3CSEA 1VDRA 3QYOA 4KFJA 3SRWX 1RX9A 4PSSA 3VCOA 3NXRA 4KL9A 3SA2A 3QG2A 1KLKA 3IROA 3UM6A 3L3RA 3NZCX 1MVTA 1M79A 1DYJA 4IXED 4LAHX 3DAUA 2LF1A 1RX5A 4I1NA 2W3WA 1RA3A 4P3RA 3DGAA 4KY8A 4KJLA 4LEKX 4ELEA 1JOMA 1DR4A 3SAIA 4KAKA 1DRHA 2W3VA 4KEBA 1DISA 1RA2A 3HBBA 4XT8A 3EIGA 4RGCA 2BL9A 1LUDA 1M78A 3FQOA 1S3YA 3NZ6X 1LY3A 1OHJA 2GD9A 4KY4A 3FY8X 3NXYA 4KJJA 1ZDRA 3S7AA 1DF7A 3FY9X 3ZPGA 3FQ0A 2C2TA 1DR3A 3GHCA 2HM9A 1DDRA 3GI2A 4DPDA 2W3AA 3RO9A 2FZJA 1JUVA 3UM5A 4QLFA 1YHOA 4XT7A 4NX7A 4QLEA 3NXOA 3EEMA 4KLXA 3FL8A 5ECCA 1DG5A 4FGGA 3EEJA 2OBCA 1RF7A 3K2HA 3GYFA 1AO8A 1RA8A 3SA1A 2FZIA 3RG9A 1DR7A 3CL9A 3OAFA 2G6VA 3TD8A 2D5NA 2P4GA 4HA7A 4H96A 3FQZA 2CD2A 1J3IA 1DAJA 2XW7A 3QYLA 5HF2X 3F91A 1QZFA 4Q0EA 4P66A 4M7VA 1HFPA 1RB3A 3QL3A 4H98A 2C2SA 1DRBA 3EX8A 3QLWA 3R33A 3FRDX 3UM8A 3JWMA 4XRBA 1RA9A 3SRQX 3F0VX 3KJRA 3NZBX 4XT6A 5HPBA 2B3ZA 3SRUX 4G3MA 4QLGA 4XE6X 3GHWA 3SR5X 1RX3A 2W9HA 1SEJA 3TQBA 1RX8A 4KD7A 3JW5A 7DFRA 4EIZA 1DDSA 1DRAA 2W9TA 4I13A 3DG8A 1LY4A 1DYIA 4PTJA 4DP3A 2HXVA 1DR1A 4ELBA 5HF0X 3ZPCA 3TQ9A 3ROAA 3FS6A 3FQFA 3FQVA 1KMVA 3S9UA 3D80A 2W3BA 1CD2A 1PD8A 4M6JA 4OR7A 3QFXA 2OIPA 3IRNA 1U71A 5HVBA 3QLXA 1DIUA 1U72A 4HOGA 4EILA 3IRMA 5HI6A 2QK8A 1PDBA 1CZ3A 3CLBA 5HSRA 3JVXA 1DRFA 3D84X 3NZ9X 1TDRA 3KGYA 5ECXA 4X5HA 3SRRX 4G95A 4CD2A 3FREX 1RX4A 3NZDA 5HQYA 3NXXA 5DXVA 1IA3A 3JSUA 1M7AA 3NRRA 3NZAX 4XECX 4XT4A 1RX7A 3JTWA 2HQPA 5HT5A 3FRBX 4KYAA 2ZZAA 1DYRA 4X5FA 2BLCA 3KFYA 2BLBA 1KMSA 3OCHA 1J3JA 4H95A 1BOZA 1RH3A 2ITHA 1AI9A 4P68A 3IX9A 4X5JA 6DFRA 1HFQA 1DHJA 4G8ZX 1OHKA 4HA9A 1S3VA 4TU5X 3FQCA 4H97A 3NU0A 3INVA 3HJ3A 1J3KA 3DL6A 1DREA 1RG7A 1DHFA 5CC9A 4KM2A 3QLYA 3FYWX 2D0KA 4M6LA 4KJKA 2W9GA 4EIGA 2JYBA 3F0BX 3F0XX 3K47A 4QJZD 1RX6A 2O7PA 3F8ZA 3IA5A 3JW3A 4QJCA 3JWFA 4PTHA 1DR6A 5HSUA 3QLRA 3FYVX 8DFRA 3E0BA 1U70A 4EJ1A 3KJSA 2KGKA 3SGYA 1DG7A 1RE7A 2ANOA 1IA1A 1DYHA 4Q0DA 2L28A 3N0HA 3SRSX 4ELHA 3SH2A 3QGTA 1IA4A 3F0SX 1RX2A 1IA2A 5HT4A 5HVEA 4KM0A 3F0UX 1D1GA
chains in the Genus database with same CATH superfamily
5HUIA 4ECKA 5E8QA 4M7UA 4X5IA 2AZNA 3QLZA 1DG8A 1RX1A 2FZHA 1RA1A 3EELA 5HQZA 3K74A 4P3QA 3TQ8A 3KY8A 4PSYA 3JWKA 1DLRA 1DR5A 4QI9A 4IXFX 3SQYX 4HOEA 4DFRA 1PD9A 4ELGA 3K45A 2INQA 4FGHA 4Q67A 1VJ3A 3JWCA 3GHVA 5JG0X 5JA3A 4HOFA 3M08A 2H2QA 3QL0A 4Q6AA 5U26A 3DFRA 1RD7A 4FHBA 2BLAA 1DR2A 1E26A 4QHVA 5FDAA 1DLSA 3F0QX 3M09A 3FL9A 4PSTA 4GH8A 3DATA 1JOLA 2W9SA 3LG4A 4LAGX 4M6KA 2CIGA 3I3RA 1AOEA 2DRCA 1DHIA 5EAJA 4KNEA 4X5GA 3TQAA 4ELFA 3I8AX 2ANQA 4KBNA 3CD2A 4DPHA 1MVSA 3NXVA 3EEKA 1BZFA 3NXTA 1RC4A 4XT5A 4IXGX 4M2XA 3Q1HA 4PDJA 1S3WA 3DRCA 3DL5A 5CCCA 4NX6A 3QLSA 3NTZA 3S3VA 1S3UA 3FRAX 3F8YA 4DDRA 5U27A 4OSGA 1RB2A 4LAEX 2DHFA 2W3MA 5DFRA 3FRFX 1HFRA 3IA4A 3CSEA 1VDRA 3QYOA 4KFJA 3SRWX 1RX9A 4PSSA 3VCOA 3NXRA 4KL9A 3SA2A 3QG2A 1KLKA 3IROA 3UM6A 3L3RA 3NZCX 1MVTA 1M79A 1DYJA 4IXED 4LAHX 3DAUA 2LF1A 1RX5A 4I1NA 2W3WA 1RA3A 4P3RA 3DGAA 4KY8A 4KJLA 4LEKX 4ELEA 1JOMA 1DR4A 3SAIA 4KAKA 1DRHA 2W3VA 4KEBA 1DISA 1RA2A 3HBBA 4XT8A 3EIGA 4RGCA 2BL9A 1LUDA 1M78A 3FQOA 1S3YA 3NZ6X 1LY3A 1OHJA 2GD9A 4KY4A 3FY8X 3NXYA 4KJJA 1ZDRA 3S7AA 1DF7A 3FY9X 3ZPGA 3FQ0A 2C2TA 1DR3A 3GHCA 2HM9A 1DDRA 3GI2A 4DPDA 2W3AA 3RO9A 2FZJA 1JUVA 3UM5A 4QLFA 1YHOA 4XT7A 4NX7A 4QLEA 3NXOA 3EEMA 4KLXA 3FL8A 5ECCA 1DG5A 4FGGA 3EEJA 2OBCA 1RF7A 3K2HA 3GYFA 1AO8A 1RA8A 3SA1A 2FZIA 3RG9A 1DR7A 3CL9A 3OAFA 2G6VA 3TD8A 2D5NA 2P4GA 4HA7A 4H96A 3FQZA 2CD2A 1J3IA 1DAJA 2XW7A 3QYLA 5HF2X 3F91A 1QZFA 4Q0EA 4P66A 4M7VA 1HFPA 1RB3A 3QL3A 4H98A 2C2SA 1DRBA 3EX8A 3QLWA 3R33A 3FRDX 3UM8A 3JWMA 4XRBA 1RA9A 3SRQX 3F0VX 3KJRA 3NZBX 4XT6A 5HPBA 2B3ZA 3SRUX 4G3MA 4QLGA 4XE6X 3GHWA 3SR5X 1RX3A 2W9HA 1SEJA 3TQBA 1RX8A 4KD7A 3JW5A 7DFRA 4EIZA 1DDSA 1DRAA 2W9TA 4I13A 3DG8A 1LY4A 1DYIA 4PTJA 4DP3A 2HXVA 1DR1A 4ELBA 5HF0X 3ZPCA 3TQ9A 3ROAA 3FS6A 3FQFA 3FQVA 1KMVA 3S9UA 3D80A 2W3BA 1CD2A 1PD8A 4M6JA 4OR7A 3QFXA 2OIPA 3IRNA 1U71A 5HVBA 3QLXA 1DIUA 1U72A 4HOGA 4EILA 3IRMA 5HI6A 2QK8A 1PDBA 1CZ3A 3CLBA 5HSRA 3JVXA 1DRFA 3D84X 3NZ9X 1TDRA 3KGYA 5ECXA 4X5HA 3SRRX 4G95A 4CD2A 3FREX 1RX4A 3NZDA 5HQYA 3NXXA 5DXVA 1IA3A 3JSUA 1M7AA 3NRRA 3NZAX 4XECX 4XT4A 1RX7A 3JTWA 2HQPA 5HT5A 3FRBX 4KYAA 2ZZAA 1DYRA 4X5FA 2BLCA 3KFYA 2BLBA 1KMSA 3OCHA 1J3JA 4H95A 1BOZA 1RH3A 2ITHA 1AI9A 4P68A 3IX9A 4X5JA 6DFRA 1HFQA 1DHJA 4G8ZX 1OHKA 4HA9A 1S3VA 4TU5X 3FQCA 4H97A 3NU0A 3INVA 3HJ3A 1J3KA 3DL6A 1DREA 1RG7A 1DHFA 5CC9A 4KM2A 3QLYA 3FYWX 2D0KA 4M6LA 4KJKA 2W9GA 4EIGA 2JYBA 3F0BX 3F0XX 3K47A 4QJZD 1RX6A 2O7PA 3F8ZA 3IA5A 3JW3A 4QJCA 3JWFA 4PTHA 1DR6A 5HSUA 3QLRA 3FYVX 8DFRA 3E0BA 1U70A 4EJ1A 3KJSA 2KGKA 3SGYA 1DG7A 1RE7A 2ANOA 1IA1A 1DYHA 4Q0DA 2L28A 3N0HA 3SRSX 4ELHA 3SH2A 3QGTA 1IA4A 3F0SX 1RX2A 1IA2A 5HT4A 5HVEA 4KM0A 3F0UX 1D1GA
chains in the Genus database with same CATH topology
5HUIA 4ECKA 5E8QA 4M7UA 4X5IA 2AZNA 3QLZA 1DG8A 1RX1A 2FZHA 1RA1A 3EELA 5HQZA 3K74A 4P3QA 3TQ8A 3KY8A 4PSYA 3JWKA 1DLRA 1DR5A 4QI9A 4IXFX 3SQYX 4HOEA 4DFRA 1PD9A 4ELGA 3K45A 2INQA 4FGHA 4Q67A 1VJ3A 3JWCA 3GHVA 5JG0X 5JA3A 4HOFA 3M08A 2H2QA 3QL0A 4Q6AA 5U26A 3DFRA 1RD7A 4FHBA 2BLAA 1DR2A 1E26A 4QHVA 5FDAA 1DLSA 3F0QX 3M09A 3FL9A 4PSTA 4GH8A 3DATA 1JOLA 2W9SA 3LG4A 4LAGX 4M6KA 2CIGA 3I3RA 1AOEA 2DRCA 1DHIA 5EAJA 4KNEA 4X5GA 3TQAA 4ELFA 3I8AX 2ANQA 4KBNA 3CD2A 4DPHA 1MVSA 3NXVA 3EEKA 1BZFA 3NXTA 1RC4A 4XT5A 4IXGX 4M2XA 3Q1HA 4PDJA 1S3WA 3DRCA 3DL5A 5CCCA 4NX6A 3QLSA 3NTZA 3S3VA 1S3UA 3FRAX 3F8YA 4DDRA 5U27A 4OSGA 1RB2A 4LAEX 2DHFA 2W3MA 5DFRA 3FRFX 1HFRA 3IA4A 3CSEA 1VDRA 3QYOA 4KFJA 3SRWX 1RX9A 4PSSA 3VCOA 3NXRA 4KL9A 3SA2A 3QG2A 1KLKA 3IROA 3UM6A 3L3RA 3NZCX 1MVTA 1M79A 1DYJA 4IXED 4LAHX 3DAUA 2LF1A 1RX5A 4I1NA 2W3WA 1RA3A 4P3RA 3DGAA 4KY8A 4KJLA 4LEKX 4ELEA 1JOMA 1DR4A 3SAIA 4KAKA 1DRHA 2W3VA 4KEBA 1DISA 1RA2A 3HBBA 4XT8A 3EIGA 4RGCA 2BL9A 1LUDA 1M78A 3FQOA 1S3YA 3NZ6X 1LY3A 1OHJA 2GD9A 4KY4A 3FY8X 3NXYA 4KJJA 1ZDRA 3S7AA 1DF7A 3FY9X 3ZPGA 3FQ0A 2C2TA 1DR3A 3GHCA 2HM9A 1DDRA 3GI2A 4DPDA 2W3AA 3RO9A 2FZJA 1JUVA 3UM5A 4QLFA 1YHOA 4XT7A 4NX7A 4QLEA 3NXOA 3EEMA 4KLXA 3FL8A 5ECCA 1DG5A 4FGGA 3EEJA 2OBCA 1RF7A 3K2HA 3GYFA 1AO8A 1RA8A 3SA1A 2FZIA 3RG9A 1DR7A 3CL9A 3OAFA 2G6VA 3TD8A 2D5NA 2P4GA 4HA7A 4H96A 3FQZA 2CD2A 1J3IA 1DAJA 2XW7A 3QYLA 5HF2X 3F91A 1QZFA 4Q0EA 4P66A 4M7VA 1HFPA 1RB3A 3QL3A 4H98A 2C2SA 1DRBA 3EX8A 3QLWA 3R33A 3FRDX 3UM8A 3JWMA 4XRBA 1RA9A 3SRQX 3F0VX 3KJRA 3NZBX 4XT6A 5HPBA 2B3ZA 3SRUX 4G3MA 4QLGA 4XE6X 3GHWA 3SR5X 1RX3A 2W9HA 1SEJA 3TQBA 1RX8A 4KD7A 3JW5A 7DFRA 4EIZA 1DDSA 1DRAA 2W9TA 4I13A 3DG8A 1LY4A 1DYIA 4PTJA 4DP3A 2HXVA 1DR1A 4ELBA 5HF0X 3ZPCA 3TQ9A 3ROAA 3FS6A 3FQFA 3FQVA 1KMVA 3S9UA 3D80A 2W3BA 1CD2A 1PD8A 4M6JA 4OR7A 3QFXA 2OIPA 3IRNA 1U71A 5HVBA 3QLXA 1DIUA 1U72A 4HOGA 4EILA 3IRMA 5HI6A 2QK8A 1PDBA 1CZ3A 3CLBA 5HSRA 3JVXA 1DRFA 3D84X 3NZ9X 1TDRA 3KGYA 5ECXA 4X5HA 3SRRX 4G95A 4CD2A 3FREX 1RX4A 3NZDA 5HQYA 3NXXA 5DXVA 1IA3A 3JSUA 1M7AA 3NRRA 3NZAX 4XECX 4XT4A 1RX7A 3JTWA 2HQPA 5HT5A 3FRBX 4KYAA 2ZZAA 1DYRA 4X5FA 2BLCA 3KFYA 2BLBA 1KMSA 3OCHA 1J3JA 4H95A 1BOZA 1RH3A 2ITHA 1AI9A 4P68A 3IX9A 4X5JA 6DFRA 1HFQA 1DHJA 4G8ZX 1OHKA 4HA9A 1S3VA 4TU5X 3FQCA 4H97A 3NU0A 3INVA 3HJ3A 1J3KA 3DL6A 1DREA 1RG7A 1DHFA 5CC9A 4KM2A 3QLYA 3FYWX 2D0KA 4M6LA 4KJKA 2W9GA 4EIGA 2JYBA 3F0BX 3F0XX 3K47A 4QJZD 1RX6A 2O7PA 3F8ZA 3IA5A 3JW3A 4QJCA 3JWFA 4PTHA 1DR6A 5HSUA 3QLRA 3FYVX 8DFRA 3E0BA 1U70A 4EJ1A 3KJSA 2KGKA 3SGYA 1DG7A 1RE7A 2ANOA 1IA1A 1DYHA 4Q0DA 2L28A 3N0HA 3SRSX 4ELHA 3SH2A 3QGTA 1IA4A 3F0SX 1RX2A 1IA2A 5HT4A 5HVEA 4KM0A 3F0UX 1D1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HUI A;  4ECK A;  5E8Q A;  4M7U A;  4X5I A;  2AZN A;  3QLZ A;  1DG8 A;  1RX1 A;  2FZH A;  1RA1 A;  3EEL A;  5HQZ A;  3K74 A;  4P3Q A;  3TQ8 A;  3KY8 A;  4PSY A;  3JWK A;  1DLR A;  1DR5 A;  4QI9 A;  4IXF X;  3SQY X;  4HOE A;  4DFR A;  1PD9 A;  4ELG A;  3K45 A;  2INQ A;  4FGH A;  4Q67 A;  1VJ3 A;  3JWC A;  3GHV A;  5JG0 X;  5JA3 A;  4HOF A;  3M08 A;  2H2Q A;  3QL0 A;  4Q6A A;  5U26 A;  3DFR A;  1RD7 A;  4FHB A;  2BLA A;  1DR2 A;  1E26 A;  4QHV A;  5FDA A;  1DLS A;  3F0Q X;  3M09 A;  3FL9 A;  4PST A;  4GH8 A;  3DAT A;  1JOL A;  2W9S A;  3LG4 A;  4LAG X;  4M6K A;  2CIG A;  3I3R A;  1AOE A;  2DRC A;  1DHI A;  5EAJ A;  4KNE A;  4X5G A;  3TQA A;  4ELF A;  3I8A X;  2ANQ A;  4KBN A;  3CD2 A;  4DPH A;  1MVS A;  3NXV A;  3EEK A;  1BZF A;  3NXT A;  1RC4 A;  4XT5 A;  4IXG X;  4M2X A;  3Q1H A;  4PDJ A;  1S3W A;  3DRC A;  3DL5 A;  5CCC A;  4NX6 A;  3QLS A;  3NTZ A;  3S3V A;  1S3U A;  3FRA X;  3F8Y A;  4DDR A;  5U27 A;  4OSG A;  1RB2 A;  4LAE X;  2DHF A;  2W3M A;  5DFR A;  3FRF X;  1HFR A;  3IA4 A;  3CSE A;  1VDR A;  3QYO A;  4KFJ A;  3SRW X;  1RX9 A;  4PSS A;  3VCO A;  3NXR A;  4KL9 A;  3SA2 A;  3QG2 A;  1KLK A;  3IRO A;  3UM6 A;  3L3R A;  3NZC X;  1MVT A;  1M79 A;  1DYJ A;  4IXE D;  4LAH X;  3DAU A;  2LF1 A;  1RX5 A;  4I1N A;  2W3W A;  1RA3 A;  4P3R A;  3DGA A;  4KY8 A;  4KJL A;  4LEK X;  4ELE A;  1JOM A;  1DR4 A;  3SAI A;  4KAK A;  1DRH A;  2W3V A;  4KEB A;  1DIS A;  1RA2 A;  3HBB A;  4XT8 A;  3EIG A;  4RGC A;  2BL9 A;  1LUD A;  1M78 A;  3FQO A;  1S3Y A;  3NZ6 X;  1LY3 A;  1OHJ A;  2GD9 A;  4KY4 A;  3FY8 X;  3NXY A;  4KJJ A;  1ZDR A;  3S7A A;  1DF7 A;  3FY9 X;  3ZPG A;  3FQ0 A;  2C2T A;  1DR3 A;  3GHC A;  2HM9 A;  1DDR A;  3GI2 A;  4DPD A;  2W3A A;  3RO9 A;  2FZJ A;  1JUV A;  3UM5 A;  4QLF A;  1YHO A;  4XT7 A;  4NX7 A;  4QLE A;  3NXO A;  3EEM A;  4KLX A;  3FL8 A;  5ECC A;  1DG5 A;  4FGG A;  3EEJ A;  2OBC A;  1RF7 A;  3K2H A;  3GYF A;  1AO8 A;  1RA8 A;  3SA1 A;  2FZI A;  3RG9 A;  1DR7 A;  3CL9 A;  3OAF A;  2G6V A;  3TD8 A;  2D5N A;  2P4G A;  4HA7 A;  4H96 A;  3FQZ A;  2CD2 A;  1J3I A;  1DAJ A;  2XW7 A;  3QYL A;  5HF2 X;  3F91 A;  1QZF A;  4Q0E A;  4P66 A;  4M7V A;  1HFP A;  1RB3 A;  3QL3 A;  4H98 A;  2C2S A;  1DRB A;  3EX8 A;  3QLW A;  3R33 A;  3FRD X;  3UM8 A;  3JWM A;  4XRB A;  1RA9 A;  3SRQ X;  3F0V X;  3KJR A;  3NZB X;  4XT6 A;  5HPB A;  2B3Z A;  3SRU X;  4G3M A;  4QLG A;  4XE6 X;  3GHW A;  3SR5 X;  1RX3 A;  2W9H A;  1SEJ A;  3TQB A;  1RX8 A;  4KD7 A;  3JW5 A;  7DFR A;  4EIZ A;  1DDS A;  1DRA A;  2W9T A;  4I13 A;  3DG8 A;  1LY4 A;  1DYI A;  4PTJ A;  4DP3 A;  2HXV A;  1DR1 A;  4ELB A;  5HF0 X;  3ZPC A;  3TQ9 A;  3ROA A;  3FS6 A;  3FQF A;  3FQV A;  1KMV A;  3S9U A;  3D80 A;  2W3B A;  1CD2 A;  1PD8 A;  4M6J A;  4OR7 A;  3QFX A;  2OIP A;  3IRN A;  1U71 A;  5HVB A;  3QLX A;  1DIU A;  1U72 A;  4HOG A;  4EIL A;  3IRM A;  5HI6 A;  2QK8 A;  1PDB A;  1CZ3 A;  3CLB A;  5HSR A;  3JVX A;  1DRF A;  3D84 X;  3NZ9 X;  1TDR A;  3KGY A;  5ECX A;  4X5H A;  3SRR X;  4G95 A;  4CD2 A;  3FRE X;  1RX4 A;  3NZD A;  5HQY A;  3NXX A;  5DXV A;  1IA3 A;  3JSU A;  1M7A A;  3NRR A;  3NZA X;  4XEC X;  4XT4 A;  1RX7 A;  3JTW A;  2HQP A;  5HT5 A;  3FRB X;  4KYA A;  2ZZA A;  1DYR A;  4X5F A;  2BLC A;  3KFY A;  2BLB A;  1KMS A;  3OCH A;  1J3J A;  4H95 A;  1BOZ A;  1RH3 A;  2ITH A;  1AI9 A;  4P68 A;  3IX9 A;  4X5J A;  6DFR A;  1HFQ A;  1DHJ A;  4G8Z X;  1OHK A;  4HA9 A;  1S3V A;  4TU5 X;  3FQC A;  4H97 A;  3NU0 A;  3INV A;  3HJ3 A;  1J3K A;  3DL6 A;  1DRE A;  1RG7 A;  1DHF A;  5CC9 A;  4KM2 A;  3QLY A;  3FYW X;  2D0K A;  4M6L A;  4KJK A;  2W9G A;  4EIG A;  2JYB A;  3F0B X;  3F0X X;  3K47 A;  4QJZ D;  1RX6 A;  2O7P A;  3F8Z A;  3IA5 A;  3JW3 A;  4QJC A;  3JWF A;  4PTH A;  1DR6 A;  5HSU A;  3QLR A;  3FYV X;  8DFR A;  3E0B A;  1U70 A;  4EJ1 A;  3KJS A;  2KGK A;  3SGY A;  1DG7 A;  1RE7 A;  2ANO A;  1IA1 A;  1DYH A;  4Q0D A;  2L28 A;  3N0H A;  3SRS X;  4ELH A;  3SH2 A;  3QGT A;  1IA4 A;  3F0S X;  1RX2 A;  1IA2 A;  5HT4 A;  5HVE A;  4KM0 A;  3F0U X;  1D1G A; 
#chains in the Genus database with same CATH topology
 5HUI A;  4ECK A;  5E8Q A;  4M7U A;  4X5I A;  2AZN A;  3QLZ A;  1DG8 A;  1RX1 A;  2FZH A;  1RA1 A;  3EEL A;  5HQZ A;  3K74 A;  4P3Q A;  3TQ8 A;  3KY8 A;  4PSY A;  3JWK A;  1DLR A;  1DR5 A;  4QI9 A;  4IXF X;  3SQY X;  4HOE A;  4DFR A;  1PD9 A;  4ELG A;  3K45 A;  2INQ A;  4FGH A;  4Q67 A;  1VJ3 A;  3JWC A;  3GHV A;  5JG0 X;  5JA3 A;  4HOF A;  3M08 A;  2H2Q A;  3QL0 A;  4Q6A A;  5U26 A;  3DFR A;  1RD7 A;  4FHB A;  2BLA A;  1DR2 A;  1E26 A;  4QHV A;  5FDA A;  1DLS A;  3F0Q X;  3M09 A;  3FL9 A;  4PST A;  4GH8 A;  3DAT A;  1JOL A;  2W9S A;  3LG4 A;  4LAG X;  4M6K A;  2CIG A;  3I3R A;  1AOE A;  2DRC A;  1DHI A;  5EAJ A;  4KNE A;  4X5G A;  3TQA A;  4ELF A;  3I8A X;  2ANQ A;  4KBN A;  3CD2 A;  4DPH A;  1MVS A;  3NXV A;  3EEK A;  1BZF A;  3NXT A;  1RC4 A;  4XT5 A;  4IXG X;  4M2X A;  3Q1H A;  4PDJ A;  1S3W A;  3DRC A;  3DL5 A;  5CCC A;  4NX6 A;  3QLS A;  3NTZ A;  3S3V A;  1S3U A;  3FRA X;  3F8Y A;  4DDR A;  5U27 A;  4OSG A;  1RB2 A;  4LAE X;  2DHF A;  2W3M A;  5DFR A;  3FRF X;  1HFR A;  3IA4 A;  3CSE A;  1VDR A;  3QYO A;  4KFJ A;  3SRW X;  1RX9 A;  4PSS A;  3VCO A;  3NXR A;  4KL9 A;  3SA2 A;  3QG2 A;  1KLK A;  3IRO A;  3UM6 A;  3L3R A;  3NZC X;  1MVT A;  1M79 A;  1DYJ A;  4IXE D;  4LAH X;  3DAU A;  2LF1 A;  1RX5 A;  4I1N A;  2W3W A;  1RA3 A;  4P3R A;  3DGA A;  4KY8 A;  4KJL A;  4LEK X;  4ELE A;  1JOM A;  1DR4 A;  3SAI A;  4KAK A;  1DRH A;  2W3V A;  4KEB A;  1DIS A;  1RA2 A;  3HBB A;  4XT8 A;  3EIG A;  4RGC A;  2BL9 A;  1LUD A;  1M78 A;  3FQO A;  1S3Y A;  3NZ6 X;  1LY3 A;  1OHJ A;  2GD9 A;  4KY4 A;  3FY8 X;  3NXY A;  4KJJ A;  1ZDR A;  3S7A A;  1DF7 A;  3FY9 X;  3ZPG A;  3FQ0 A;  2C2T A;  1DR3 A;  3GHC A;  2HM9 A;  1DDR A;  3GI2 A;  4DPD A;  2W3A A;  3RO9 A;  2FZJ A;  1JUV A;  3UM5 A;  4QLF A;  1YHO A;  4XT7 A;  4NX7 A;  4QLE A;  3NXO A;  3EEM A;  4KLX A;  3FL8 A;  5ECC A;  1DG5 A;  4FGG A;  3EEJ A;  2OBC A;  1RF7 A;  3K2H A;  3GYF A;  1AO8 A;  1RA8 A;  3SA1 A;  2FZI A;  3RG9 A;  1DR7 A;  3CL9 A;  3OAF A;  2G6V A;  3TD8 A;  2D5N A;  2P4G A;  4HA7 A;  4H96 A;  3FQZ A;  2CD2 A;  1J3I A;  1DAJ A;  2XW7 A;  3QYL A;  5HF2 X;  3F91 A;  1QZF A;  4Q0E A;  4P66 A;  4M7V A;  1HFP A;  1RB3 A;  3QL3 A;  4H98 A;  2C2S A;  1DRB A;  3EX8 A;  3QLW A;  3R33 A;  3FRD X;  3UM8 A;  3JWM A;  4XRB A;  1RA9 A;  3SRQ X;  3F0V X;  3KJR A;  3NZB X;  4XT6 A;  5HPB A;  2B3Z A;  3SRU X;  4G3M A;  4QLG A;  4XE6 X;  3GHW A;  3SR5 X;  1RX3 A;  2W9H A;  1SEJ A;  3TQB A;  1RX8 A;  4KD7 A;  3JW5 A;  7DFR A;  4EIZ A;  1DDS A;  1DRA A;  2W9T A;  4I13 A;  3DG8 A;  1LY4 A;  1DYI A;  4PTJ A;  4DP3 A;  2HXV A;  1DR1 A;  4ELB A;  5HF0 X;  3ZPC A;  3TQ9 A;  3ROA A;  3FS6 A;  3FQF A;  3FQV A;  1KMV A;  3S9U A;  3D80 A;  2W3B A;  1CD2 A;  1PD8 A;  4M6J A;  4OR7 A;  3QFX A;  2OIP A;  3IRN A;  1U71 A;  5HVB A;  3QLX A;  1DIU A;  1U72 A;  4HOG A;  4EIL A;  3IRM A;  5HI6 A;  2QK8 A;  1PDB A;  1CZ3 A;  3CLB A;  5HSR A;  3JVX A;  1DRF A;  3D84 X;  3NZ9 X;  1TDR A;  3KGY A;  5ECX A;  4X5H A;  3SRR X;  4G95 A;  4CD2 A;  3FRE X;  1RX4 A;  3NZD A;  5HQY A;  3NXX A;  5DXV A;  1IA3 A;  3JSU A;  1M7A A;  3NRR A;  3NZA X;  4XEC X;  4XT4 A;  1RX7 A;  3JTW A;  2HQP A;  5HT5 A;  3FRB X;  4KYA A;  2ZZA A;  1DYR A;  4X5F A;  2BLC A;  3KFY A;  2BLB A;  1KMS A;  3OCH A;  1J3J A;  4H95 A;  1BOZ A;  1RH3 A;  2ITH A;  1AI9 A;  4P68 A;  3IX9 A;  4X5J A;  6DFR A;  1HFQ A;  1DHJ A;  4G8Z X;  1OHK A;  4HA9 A;  1S3V A;  4TU5 X;  3FQC A;  4H97 A;  3NU0 A;  3INV A;  3HJ3 A;  1J3K A;  3DL6 A;  1DRE A;  1RG7 A;  1DHF A;  5CC9 A;  4KM2 A;  3QLY A;  3FYW X;  2D0K A;  4M6L A;  4KJK A;  2W9G A;  4EIG A;  2JYB A;  3F0B X;  3F0X X;  3K47 A;  4QJZ D;  1RX6 A;  2O7P A;  3F8Z A;  3IA5 A;  3JW3 A;  4QJC A;  3JWF A;  4PTH A;  1DR6 A;  5HSU A;  3QLR A;  3FYV X;  8DFR A;  3E0B A;  1U70 A;  4EJ1 A;  3KJS A;  2KGK A;  3SGY A;  1DG7 A;  1RE7 A;  2ANO A;  1IA1 A;  1DYH A;  4Q0D A;  2L28 A;  3N0H A;  3SRS X;  4ELH A;  3SH2 A;  3QGT A;  1IA4 A;  3F0S X;  1RX2 A;  1IA2 A;  5HT4 A;  5HVE A;  4KM0 A;  3F0U X;  1D1G A; 
#chains in the Genus database with same CATH homology
 5HUI A;  4ECK A;  5E8Q A;  4M7U A;  4X5I A;  2AZN A;  3QLZ A;  1DG8 A;  1RX1 A;  2FZH A;  1RA1 A;  3EEL A;  5HQZ A;  3K74 A;  4P3Q A;  3TQ8 A;  3KY8 A;  4PSY A;  3JWK A;  1DLR A;  1DR5 A;  4QI9 A;  4IXF X;  3SQY X;  4HOE A;  4DFR A;  1PD9 A;  4ELG A;  3K45 A;  2INQ A;  4FGH A;  4Q67 A;  1VJ3 A;  3JWC A;  3GHV A;  5JG0 X;  5JA3 A;  4HOF A;  3M08 A;  2H2Q A;  3QL0 A;  4Q6A A;  5U26 A;  3DFR A;  1RD7 A;  4FHB A;  2BLA A;  1DR2 A;  1E26 A;  4QHV A;  5FDA A;  1DLS A;  3F0Q X;  3M09 A;  3FL9 A;  4PST A;  4GH8 A;  3DAT A;  1JOL A;  2W9S A;  3LG4 A;  4LAG X;  4M6K A;  2CIG A;  3I3R A;  1AOE A;  2DRC A;  1DHI A;  5EAJ A;  4KNE A;  4X5G A;  3TQA A;  4ELF A;  3I8A X;  2ANQ A;  4KBN A;  3CD2 A;  4DPH A;  1MVS A;  3NXV A;  3EEK A;  1BZF A;  3NXT A;  1RC4 A;  4XT5 A;  4IXG X;  4M2X A;  3Q1H A;  4PDJ A;  1S3W A;  3DRC A;  3DL5 A;  5CCC A;  4NX6 A;  3QLS A;  3NTZ A;  3S3V A;  1S3U A;  3FRA X;  3F8Y A;  4DDR A;  5U27 A;  4OSG A;  1RB2 A;  4LAE X;  2DHF A;  2W3M A;  5DFR A;  3FRF X;  1HFR A;  3IA4 A;  3CSE A;  1VDR A;  3QYO A;  4KFJ A;  3SRW X;  1RX9 A;  4PSS A;  3VCO A;  3NXR A;  4KL9 A;  3SA2 A;  3QG2 A;  1KLK A;  3IRO A;  3UM6 A;  3L3R A;  3NZC X;  1MVT A;  1M79 A;  1DYJ A;  4IXE D;  4LAH X;  3DAU A;  2LF1 A;  1RX5 A;  4I1N A;  2W3W A;  1RA3 A;  4P3R A;  3DGA A;  4KY8 A;  4KJL A;  4LEK X;  4ELE A;  1JOM A;  1DR4 A;  3SAI A;  4KAK A;  1DRH A;  2W3V A;  4KEB A;  1DIS A;  1RA2 A;  3HBB A;  4XT8 A;  3EIG A;  4RGC A;  2BL9 A;  1LUD A;  1M78 A;  3FQO A;  1S3Y A;  3NZ6 X;  1LY3 A;  1OHJ A;  2GD9 A;  4KY4 A;  3FY8 X;  3NXY A;  4KJJ A;  1ZDR A;  3S7A A;  1DF7 A;  3FY9 X;  3ZPG A;  3FQ0 A;  2C2T A;  1DR3 A;  3GHC A;  2HM9 A;  1DDR A;  3GI2 A;  4DPD A;  2W3A A;  3RO9 A;  2FZJ A;  1JUV A;  3UM5 A;  4QLF A;  1YHO A;  4XT7 A;  4NX7 A;  4QLE A;  3NXO A;  3EEM A;  4KLX A;  3FL8 A;  5ECC A;  1DG5 A;  4FGG A;  3EEJ A;  2OBC A;  1RF7 A;  3K2H A;  3GYF A;  1AO8 A;  1RA8 A;  3SA1 A;  2FZI A;  3RG9 A;  1DR7 A;  3CL9 A;  3OAF A;  2G6V A;  3TD8 A;  2D5N A;  2P4G A;  4HA7 A;  4H96 A;  3FQZ A;  2CD2 A;  1J3I A;  1DAJ A;  2XW7 A;  3QYL A;  5HF2 X;  3F91 A;  1QZF A;  4Q0E A;  4P66 A;  4M7V A;  1HFP A;  1RB3 A;  3QL3 A;  4H98 A;  2C2S A;  1DRB A;  3EX8 A;  3QLW A;  3R33 A;  3FRD X;  3UM8 A;  3JWM A;  4XRB A;  1RA9 A;  3SRQ X;  3F0V X;  3KJR A;  3NZB X;  4XT6 A;  5HPB A;  2B3Z A;  3SRU X;  4G3M A;  4QLG A;  4XE6 X;  3GHW A;  3SR5 X;  1RX3 A;  2W9H A;  1SEJ A;  3TQB A;  1RX8 A;  4KD7 A;  3JW5 A;  7DFR A;  4EIZ A;  1DDS A;  1DRA A;  2W9T A;  4I13 A;  3DG8 A;  1LY4 A;  1DYI A;  4PTJ A;  4DP3 A;  2HXV A;  1DR1 A;  4ELB A;  5HF0 X;  3ZPC A;  3TQ9 A;  3ROA A;  3FS6 A;  3FQF A;  3FQV A;  1KMV A;  3S9U A;  3D80 A;  2W3B A;  1CD2 A;  1PD8 A;  4M6J A;  4OR7 A;  3QFX A;  2OIP A;  3IRN A;  1U71 A;  5HVB A;  3QLX A;  1DIU A;  1U72 A;  4HOG A;  4EIL A;  3IRM A;  5HI6 A;  2QK8 A;  1PDB A;  1CZ3 A;  3CLB A;  5HSR A;  3JVX A;  1DRF A;  3D84 X;  3NZ9 X;  1TDR A;  3KGY A;  5ECX A;  4X5H A;  3SRR X;  4G95 A;  4CD2 A;  3FRE X;  1RX4 A;  3NZD A;  5HQY A;  3NXX A;  5DXV A;  1IA3 A;  3JSU A;  1M7A A;  3NRR A;  3NZA X;  4XEC X;  4XT4 A;  1RX7 A;  3JTW A;  2HQP A;  5HT5 A;  3FRB X;  4KYA A;  2ZZA A;  1DYR A;  4X5F A;  2BLC A;  3KFY A;  2BLB A;  1KMS A;  3OCH A;  1J3J A;  4H95 A;  1BOZ A;  1RH3 A;  2ITH A;  1AI9 A;  4P68 A;  3IX9 A;  4X5J A;  6DFR A;  1HFQ A;  1DHJ A;  4G8Z X;  1OHK A;  4HA9 A;  1S3V A;  4TU5 X;  3FQC A;  4H97 A;  3NU0 A;  3INV A;  3HJ3 A;  1J3K A;  3DL6 A;  1DRE A;  1RG7 A;  1DHF A;  5CC9 A;  4KM2 A;  3QLY A;  3FYW X;  2D0K A;  4M6L A;  4KJK A;  2W9G A;  4EIG A;  2JYB A;  3F0B X;  3F0X X;  3K47 A;  4QJZ D;  1RX6 A;  2O7P A;  3F8Z A;  3IA5 A;  3JW3 A;  4QJC A;  3JWF A;  4PTH A;  1DR6 A;  5HSU A;  3QLR A;  3FYV X;  8DFR A;  3E0B A;  1U70 A;  4EJ1 A;  3KJS A;  2KGK A;  3SGY A;  1DG7 A;  1RE7 A;  2ANO A;  1IA1 A;  1DYH A;  4Q0D A;  2L28 A;  3N0H A;  3SRS X;  4ELH A;  3SH2 A;  3QGT A;  1IA4 A;  3F0S X;  1RX2 A;  1IA2 A;  5HT4 A;  5HVE A;  4KM0 A;  3F0U X;  1D1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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